Motif ID: GGCAGUG
Z-value: 0.851

Mature miRNA associated with seed GGCAGUG:
Name | miRBase Accession |
---|---|
hsa-miR-34a-5p | MIMAT0000255 |
hsa-miR-34c-5p | MIMAT0000686 |
hsa-miR-449a | MIMAT0001541 |
hsa-miR-449b-5p | MIMAT0003327 |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 137 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.7 | GO:2000097 | chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
0.4 | 1.6 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
0.0 | 1.3 | GO:0060325 | face morphogenesis(GO:0060325) |
0.2 | 1.2 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) |
0.0 | 1.2 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
0.2 | 1.1 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
0.2 | 1.1 | GO:2000669 | positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669) |
0.3 | 1.0 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
0.1 | 1.0 | GO:0007028 | cytoplasm organization(GO:0007028) |
0.3 | 0.9 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
0.1 | 0.9 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
0.1 | 0.9 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
0.1 | 0.8 | GO:0097338 | response to clozapine(GO:0097338) |
0.1 | 0.8 | GO:0051561 | positive regulation of mitochondrial calcium ion concentration(GO:0051561) |
0.2 | 0.7 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
0.2 | 0.7 | GO:0046035 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
0.1 | 0.7 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.2 | 0.6 | GO:0044805 | late nucleophagy(GO:0044805) |
0.1 | 0.6 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.1 | 0.6 | GO:0090170 | regulation of Golgi inheritance(GO:0090170) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 60 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 2.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.0 | 2.0 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
0.1 | 1.2 | GO:0033643 | host cell part(GO:0033643) |
0.0 | 1.1 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.1 | 1.0 | GO:0033010 | paranodal junction(GO:0033010) |
0.0 | 0.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.1 | 0.8 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
0.1 | 0.8 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
0.1 | 0.8 | GO:0016600 | flotillin complex(GO:0016600) |
0.0 | 0.8 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.0 | 0.8 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.8 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.0 | 0.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.7 | GO:0031526 | brush border membrane(GO:0031526) |
0.2 | 0.6 | GO:1990032 | parallel fiber(GO:1990032) |
0.2 | 0.6 | GO:0030934 | anchoring collagen complex(GO:0030934) |
0.0 | 0.6 | GO:0005640 | nuclear outer membrane(GO:0005640) |
0.0 | 0.6 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
0.1 | 0.5 | GO:0005826 | actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513) |
0.1 | 0.5 | GO:0070695 | FHF complex(GO:0070695) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 90 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 3.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.1 | 1.2 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.3 | 1.0 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.0 | 0.9 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.8 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.0 | 0.8 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.8 | GO:0038191 | neuropilin binding(GO:0038191) |
0.0 | 0.8 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
0.1 | 0.7 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.1 | 0.7 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
0.0 | 0.7 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
0.0 | 0.7 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
0.0 | 0.7 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.0 | 0.7 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 0.7 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.2 | 0.6 | GO:0098770 | FBXO family protein binding(GO:0098770) |
0.2 | 0.6 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
0.1 | 0.6 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.1 | 0.6 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
0.1 | 0.6 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
Gene overrepresentation in C2:CP category:
Showing 1 to 18 of 18 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 2.7 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 2.0 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.0 | 1.5 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 1.1 | PID_RET_PATHWAY | Signaling events regulated by Ret tyrosine kinase |
0.0 | 1.1 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
0.0 | 0.9 | PID_IL3_PATHWAY | IL3-mediated signaling events |
0.0 | 0.9 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.7 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
0.0 | 0.7 | PID_IL2_STAT5_PATHWAY | IL2 signaling events mediated by STAT5 |
0.0 | 0.7 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 0.6 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.0 | 0.6 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
0.0 | 0.6 | NABA_COLLAGENS | Genes encoding collagen proteins |
0.0 | 0.5 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.0 | 0.4 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.0 | 0.4 | PID_S1P_S1P4_PATHWAY | S1P4 pathway |
0.0 | 0.2 | PID_PDGFRA_PATHWAY | PDGFR-alpha signaling pathway |
0.0 | 0.1 | ST_STAT3_PATHWAY | STAT3 Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 25 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.8 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.0 | 1.5 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
0.1 | 1.3 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.0 | 1.0 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.9 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.8 | REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 0.7 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
0.0 | 0.7 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 0.6 | REACTOME_RAF_MAP_KINASE_CASCADE | Genes involved in RAF/MAP kinase cascade |
0.0 | 0.6 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | Genes involved in Signaling by constitutively active EGFR |
0.0 | 0.6 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
0.0 | 0.6 | REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
0.0 | 0.6 | REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
0.0 | 0.5 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.0 | 0.5 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.5 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
0.0 | 0.4 | REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
0.0 | 0.4 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.0 | 0.4 | REACTOME_PYRUVATE_METABOLISM | Genes involved in Pyruvate metabolism |
0.0 | 0.4 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |