Motif ID: GFI1B

Z-value: 0.549


Transcription factors associated with GFI1B:

Gene SymbolEntrez IDGene Name
GFI1B ENSG00000165702.8 GFI1B

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GFI1Bhg19_v2_chr9_+_135854091_135854159-0.271.9e-01Click!


Activity profile for motif GFI1B.

activity profile for motif GFI1B


Sorted Z-values histogram for motif GFI1B

Sorted Z-values for motif GFI1B



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_-_43916296 1.639 ENST00000398352.3
 RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr21_-_43916433 1.155 ENST00000291536.3
 RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr15_+_71228826 1.149 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
 LRRC49




leucine rich repeat containing 49




chr20_+_56725952 1.066 ENST00000371168.3
 C20orf85
chromosome 20 open reading frame 85
chr19_+_41620335 1.008 ENST00000331105.2
 CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr5_-_137475071 0.962 ENST00000265191.2
 NME5
NME/NM23 family member 5
chr18_+_77905894 0.830 ENST00000589574.1
ENST00000588226.1
ENST00000585422.1
 AC139100.2


Uncharacterized protein


chr17_-_19281203 0.827 ENST00000487415.2
 B9D1
B9 protein domain 1
chr3_-_158450231 0.792 ENST00000479756.1
 RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr11_+_71791849 0.773 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
 LRTOMT




leucine rich transmembrane and O-methyltransferase domain containing




chr4_+_15471489 0.763 ENST00000424120.1
ENST00000413206.1
ENST00000438599.2
ENST00000511544.1
ENST00000512702.1
ENST00000507954.1
ENST00000515124.1
ENST00000503292.1
ENST00000503658.1
 CC2D2A








coiled-coil and C2 domain containing 2A








chr11_+_111385497 0.758 ENST00000375618.4
ENST00000529167.1
ENST00000332814.6
 C11orf88


chromosome 11 open reading frame 88


chr3_-_158450475 0.739 ENST00000237696.5
 RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr11_+_71791693 0.669 ENST00000289488.2
ENST00000447974.1
 LRTOMT

leucine rich transmembrane and O-methyltransferase domain containing

chr4_+_39184024 0.663 ENST00000399820.3
ENST00000509560.1
ENST00000512112.1
ENST00000288634.7
ENST00000506503.1
 WDR19




WD repeat domain 19




chr11_+_101785727 0.659 ENST00000263468.8
 KIAA1377
KIAA1377
chr11_+_71791803 0.618 ENST00000539271.1
 LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr14_-_106069247 0.580 ENST00000479229.1
 RP11-731F5.1
RP11-731F5.1
chr5_+_36608422 0.580 ENST00000381918.3
 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr7_-_6007070 0.541 ENST00000337579.3
 RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 69 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 GO:0035082 axoneme assembly(GO:0035082)
0.1 2.3 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 1.0 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.8 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.8 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.8 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.8 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.2 0.7 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.6 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 0.6 GO:0006537 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.5 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.5 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0097186 amelogenesis(GO:0097186)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.3 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.3 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.8 GO:0072687 meiotic spindle(GO:0072687)
0.1 1.9 GO:0036038 MKS complex(GO:0036038)
0.1 0.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:0097386 glial cell projection(GO:0097386)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 1.1 GO:0070330 aromatase activity(GO:0070330)
0.0 1.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.5 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.3 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.3 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.2 GO:0043199 sulfate binding(GO:0043199)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID_ALK2_PATHWAY ALK2 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 1.1 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.7 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol