Motif ID: GCUGGUG

Z-value: 0.375


Mature miRNA associated with seed GCUGGUG:

NamemiRBase Accession
hsa-miR-138-5p MIMAT0000430



Activity profile for motif GCUGGUG.

activity profile for motif GCUGGUG


Sorted Z-values histogram for motif GCUGGUG

Sorted Z-values for motif GCUGGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUGGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_160473996 0.846 ENST00000498165.1
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr15_-_68498376 0.661 ENST00000540479.1
ENST00000395465.3
CALML4

calmodulin-like 4

chr4_-_23891693 0.616 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr19_-_14316980 0.481 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr20_+_42086525 0.474 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr19_+_13135386 0.471 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX


nuclear factor I/X (CCAAT-binding transcription factor)


chr3_-_13009168 0.431 ENST00000273221.4
IQSEC1
IQ motif and Sec7 domain 1
chr20_+_54933971 0.416 ENST00000371384.3
ENST00000437418.1
FAM210B

family with sequence similarity 210, member B

chr6_+_39760783 0.389 ENST00000398904.2
ENST00000538976.1
DAAM2

dishevelled associated activator of morphogenesis 2

chr1_+_61547894 0.372 ENST00000403491.3
NFIA
nuclear factor I/A
chr9_+_17579084 0.367 ENST00000380607.4
SH3GL2
SH3-domain GRB2-like 2
chr16_+_69599861 0.350 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr4_+_41362796 0.348 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1




LIM and calponin homology domains 1




chr7_+_90225796 0.343 ENST00000380050.3
CDK14
cyclin-dependent kinase 14
chr19_+_51815102 0.341 ENST00000270642.8
IGLON5
IgLON family member 5
chr5_+_167718604 0.338 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr5_+_139175380 0.322 ENST00000274710.3
PSD2
pleckstrin and Sec7 domain containing 2
chr3_-_114790179 0.318 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_210406121 0.313 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr10_+_72164135 0.305 ENST00000373218.4
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr16_+_58549378 0.289 ENST00000310682.2
ENST00000394266.4
ENST00000219315.4
SETD6


SET domain containing 6


chr18_-_53255766 0.281 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4




transcription factor 4




chr2_+_10183651 0.276 ENST00000305883.1
KLF11
Kruppel-like factor 11
chr14_-_25519095 0.264 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6



syntaxin binding protein 6 (amisyn)



chr20_+_36531499 0.261 ENST00000373458.3
ENST00000373461.4
ENST00000373459.4
VSTM2L


V-set and transmembrane domain containing 2 like


chr2_+_86947296 0.256 ENST00000283632.4
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_-_213403565 0.252 ENST00000342788.4
ENST00000436443.1
ERBB4

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

chr18_+_67956135 0.249 ENST00000397942.3
SOCS6
suppressor of cytokine signaling 6
chrX_+_9431324 0.246 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr15_-_43877062 0.245 ENST00000381885.1
ENST00000396923.3
PPIP5K1

diphosphoinositol pentakisphosphate kinase 1

chr16_-_87525651 0.243 ENST00000268616.4
ZCCHC14
zinc finger, CCHC domain containing 14
chr15_-_48470558 0.240 ENST00000324324.7
MYEF2
myelin expression factor 2
chr7_-_103629963 0.239 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN


reelin


chr12_+_113495492 0.234 ENST00000257600.3
DTX1
deltex homolog 1 (Drosophila)
chr4_-_2264015 0.223 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr1_+_27719148 0.216 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr9_-_130679257 0.214 ENST00000361444.3
ENST00000335791.5
ENST00000343609.2
ST6GALNAC4


ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4


chr11_-_130184555 0.209 ENST00000525842.1
ZBTB44
zinc finger and BTB domain containing 44
chr1_+_114472222 0.205 ENST00000369558.1
ENST00000369561.4
HIPK1

homeodomain interacting protein kinase 1

chr11_+_58939965 0.204 ENST00000227451.3
DTX4
deltex homolog 4 (Drosophila)
chr20_-_4982132 0.202 ENST00000338244.1
ENST00000424750.2
SLC23A2

solute carrier family 23 (ascorbic acid transporter), member 2

chr2_+_26915584 0.194 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr3_-_53080047 0.194 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1



Scm-like with four mbt domains 1



chr12_+_111843749 0.194 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr11_+_100558384 0.193 ENST00000524892.2
ENST00000298815.8
ARHGAP42

Rho GTPase activating protein 42

chr6_+_41514078 0.185 ENST00000373063.3
ENST00000373060.1
FOXP4

forkhead box P4

chr15_-_74988281 0.184 ENST00000566828.1
ENST00000563009.1
ENST00000568176.1
ENST00000566243.1
ENST00000566219.1
ENST00000426797.3
ENST00000566119.1
ENST00000315127.4
EDC3







enhancer of mRNA decapping 3







chr22_-_44894178 0.181 ENST00000341255.3
LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr9_-_95896550 0.180 ENST00000375446.4
NINJ1
ninjurin 1
chr1_+_180601139 0.180 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr7_-_152133059 0.172 ENST00000262189.6
ENST00000355193.2
KMT2C

lysine (K)-specific methyltransferase 2C

chr20_-_3996036 0.171 ENST00000336095.6
RNF24
ring finger protein 24
chr5_-_176057365 0.170 ENST00000310112.3
SNCB
synuclein, beta
chr8_+_62200509 0.167 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1


clavesin 1


chr20_+_33292068 0.166 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2


tumor protein p53 inducible nuclear protein 2


chr11_-_67980744 0.164 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
SUV420H1


suppressor of variegation 4-20 homolog 1 (Drosophila)


chr2_+_14772810 0.164 ENST00000295092.2
ENST00000331243.4
FAM84A

family with sequence similarity 84, member A

chr11_-_75062730 0.163 ENST00000420843.2
ENST00000360025.3
ARRB1

arrestin, beta 1

chr10_+_76586348 0.157 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B


K(lysine) acetyltransferase 6B


chr15_-_68521996 0.156 ENST00000418702.2
ENST00000565471.1
ENST00000564752.1
ENST00000566347.1
ENST00000249806.5
ENST00000562767.1
CLN6




RP11-315D16.2
ceroid-lipofuscinosis, neuronal 6, late infantile, variant




Uncharacterized protein
chr10_-_73533255 0.155 ENST00000394957.3
C10orf54
chromosome 10 open reading frame 54
chr6_+_4021554 0.150 ENST00000337659.6
PRPF4B
pre-mRNA processing factor 4B
chr20_+_32077880 0.150 ENST00000342704.6
ENST00000375279.2
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr10_+_180987 0.145 ENST00000381591.1
ZMYND11
zinc finger, MYND-type containing 11
chr7_+_128864848 0.144 ENST00000325006.3
ENST00000446544.2
AHCYL2

adenosylhomocysteinase-like 2

chr17_+_7608511 0.140 ENST00000226091.2
EFNB3
ephrin-B3
chr6_+_158957431 0.139 ENST00000367090.3
TMEM181
transmembrane protein 181
chr17_+_35294075 0.136 ENST00000254457.5
LHX1
LIM homeobox 1
chr2_-_160472952 0.134 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B



bromodomain adjacent to zinc finger domain, 2B



chr10_+_69644404 0.134 ENST00000212015.6
SIRT1
sirtuin 1
chr17_-_9929581 0.132 ENST00000437099.2
ENST00000396115.2
GAS7

growth arrest-specific 7

chr1_+_9294822 0.132 ENST00000377403.2
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr10_+_102295616 0.132 ENST00000299163.6
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr11_-_47600320 0.132 ENST00000525720.1
ENST00000531067.1
ENST00000533290.1
ENST00000529499.1
ENST00000529946.1
ENST00000526005.1
ENST00000395288.2
ENST00000534239.1
KBTBD4







kelch repeat and BTB (POZ) domain containing 4







chr19_+_47421933 0.131 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr4_+_184826418 0.129 ENST00000308497.4
ENST00000438269.1
STOX2

storkhead box 2

chr15_+_44719394 0.125 ENST00000260327.4
ENST00000396780.1
CTDSPL2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2

chr7_+_8008418 0.125 ENST00000223145.5
GLCCI1
glucocorticoid induced transcript 1
chr6_+_41888926 0.124 ENST00000230340.4
BYSL
bystin-like
chr4_-_140098339 0.124 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr19_+_56652686 0.123 ENST00000592949.1
ZNF444
zinc finger protein 444
chr15_-_75744014 0.123 ENST00000394947.3
ENST00000565264.1
SIN3A

SIN3 transcription regulator family member A

chr17_-_43568062 0.120 ENST00000421073.2
ENST00000584420.1
ENST00000589780.1
ENST00000430334.3
PLEKHM1



pleckstrin homology domain containing, family M (with RUN domain) member 1



chr18_+_46065393 0.120 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr5_-_90679145 0.120 ENST00000265138.3
ARRDC3
arrestin domain containing 3
chr20_+_43991668 0.118 ENST00000243918.5
ENST00000426004.1
SYS1

SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr2_-_178483694 0.118 ENST00000355689.5
TTC30A
tetratricopeptide repeat domain 30A
chr12_-_30848914 0.116 ENST00000256079.4
IPO8
importin 8
chr5_+_49961727 0.115 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
PARP8


poly (ADP-ribose) polymerase family, member 8


chr11_-_94964354 0.115 ENST00000536441.1
SESN3
sestrin 3
chr5_-_73937244 0.110 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ENC1


ectodermal-neural cortex 1 (with BTB domain)


chr3_-_171178157 0.107 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK




TRAF2 and NCK interacting kinase




chr2_+_148602058 0.107 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
ACVR2A


activin A receptor, type IIA


chr9_+_100615536 0.106 ENST00000375123.3
FOXE1
forkhead box E1 (thyroid transcription factor 2)
chr22_-_50746027 0.106 ENST00000425954.1
ENST00000449103.1
PLXNB2

plexin B2

chr2_-_97535708 0.106 ENST00000305476.5
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr2_+_208394616 0.104 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1


cAMP responsive element binding protein 1


chr6_-_100912785 0.104 ENST00000369208.3
SIM1
single-minded family bHLH transcription factor 1
chr5_-_74162605 0.104 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A


family with sequence similarity 169, member A


chr9_+_129677039 0.102 ENST00000259351.5
ENST00000424082.2
ENST00000394022.3
ENST00000394011.3
ENST00000319107.4
RALGPS1




Ral GEF with PH domain and SH3 binding motif 1




chrX_+_69664706 0.101 ENST00000194900.4
ENST00000374360.3
DLG3

discs, large homolog 3 (Drosophila)

chr1_-_23886285 0.101 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr9_-_33264676 0.100 ENST00000472232.3
ENST00000379704.2
BAG1

BCL2-associated athanogene

chr15_+_52043758 0.100 ENST00000249700.4
ENST00000539962.2
TMOD2

tropomodulin 2 (neuronal)

chr11_+_66234216 0.100 ENST00000349459.6
ENST00000320740.7
ENST00000524466.1
ENST00000526296.1
PELI3



pellino E3 ubiquitin protein ligase family member 3



chr5_-_56247935 0.099 ENST00000381199.3
ENST00000381226.3
ENST00000381213.3
MIER3


mesoderm induction early response 1, family member 3


chrX_+_152599604 0.099 ENST00000370251.3
ENST00000421401.3
ZNF275

zinc finger protein 275

chr13_+_111365602 0.099 ENST00000333219.7
ING1
inhibitor of growth family, member 1
chr16_+_68344981 0.096 ENST00000441236.1
ENST00000348497.4
ENST00000339507.5
PRMT7


protein arginine methyltransferase 7


chr20_+_32581452 0.096 ENST00000375114.3
ENST00000448364.1
RALY

RALY heterogeneous nuclear ribonucleoprotein

chr1_-_211752073 0.095 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr3_-_33481835 0.093 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr13_-_101327028 0.093 ENST00000328767.5
ENST00000342624.5
ENST00000376234.3
ENST00000423847.1
TMTC4



transmembrane and tetratricopeptide repeat containing 4



chr17_+_72983674 0.092 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chr5_+_175792459 0.092 ENST00000310389.5
ARL10
ADP-ribosylation factor-like 10
chr17_+_36861735 0.091 ENST00000378137.5
ENST00000325718.7
MLLT6

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6

chr17_-_73775839 0.089 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B




H3 histone, family 3B (H3.3B)




chr5_-_114880533 0.088 ENST00000274457.3
FEM1C
fem-1 homolog c (C. elegans)
chr16_+_67876180 0.087 ENST00000303596.1
THAP11
THAP domain containing 11
chr15_+_49170083 0.085 ENST00000530028.2
EID1
EP300 interacting inhibitor of differentiation 1
chr2_-_26101374 0.085 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr2_+_24714729 0.085 ENST00000406961.1
ENST00000405141.1
NCOA1

nuclear receptor coactivator 1

chr5_-_94620239 0.084 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr17_+_2240775 0.084 ENST00000268989.3
ENST00000426855.2
SGSM2

small G protein signaling modulator 2

chr22_-_38240412 0.082 ENST00000215941.4
ANKRD54
ankyrin repeat domain 54
chr13_+_77564795 0.082 ENST00000377453.3
CLN5
ceroid-lipofuscinosis, neuronal 5
chr1_-_31712401 0.081 ENST00000373736.2
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr2_-_240322643 0.081 ENST00000345617.3
HDAC4
histone deacetylase 4
chr13_-_107220455 0.079 ENST00000400198.3
ARGLU1
arginine and glutamate rich 1
chr2_-_153574480 0.076 ENST00000410080.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr4_+_52709229 0.076 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCUN1D4


DCN1, defective in cullin neddylation 1, domain containing 4


chr7_-_72936531 0.075 ENST00000339594.4
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr7_-_30029367 0.074 ENST00000242059.5
SCRN1
secernin 1
chr20_+_10199468 0.073 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chr5_-_44388899 0.072 ENST00000264664.4
FGF10
fibroblast growth factor 10
chr6_+_147525541 0.071 ENST00000367481.3
ENST00000546097.1
STXBP5

syntaxin binding protein 5 (tomosyn)

chr14_+_71374122 0.069 ENST00000304743.2
ENST00000238570.5
PCNX

pecanex homolog (Drosophila)

chr15_+_52311398 0.069 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chrX_-_102531717 0.068 ENST00000372680.1
TCEAL5
transcription elongation factor A (SII)-like 5
chr8_-_116681221 0.068 ENST00000395715.3
TRPS1
trichorhinophalangeal syndrome I
chr7_-_149194843 0.067 ENST00000458143.2
ENST00000340622.3
ZNF746

zinc finger protein 746

chr11_-_46142948 0.067 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr7_+_94285637 0.067 ENST00000482108.1
ENST00000488574.1
PEG10

paternally expressed 10

chr11_-_129062093 0.066 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr1_-_110052302 0.066 ENST00000369864.4
ENST00000369862.1
AMIGO1

adhesion molecule with Ig-like domain 1

chr12_+_122516626 0.065 ENST00000319080.7
MLXIP
MLX interacting protein
chr15_+_92396920 0.063 ENST00000318445.6
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr17_-_6459768 0.062 ENST00000421306.3
PITPNM3
PITPNM family member 3
chr5_+_149109825 0.062 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B


peroxisome proliferator-activated receptor gamma, coactivator 1 beta


chr11_-_77532050 0.061 ENST00000308488.6
RSF1
remodeling and spacing factor 1
chr10_-_65225722 0.061 ENST00000399251.1
JMJD1C
jumonji domain containing 1C
chr19_+_10123925 0.059 ENST00000591589.1
ENST00000171214.1
RDH8

retinol dehydrogenase 8 (all-trans)

chr12_-_92539614 0.059 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr16_-_29910365 0.059 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
SEZ6L2



seizure related 6 homolog (mouse)-like 2



chr3_-_79068594 0.058 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr9_-_127905736 0.057 ENST00000336505.6
ENST00000373549.4
SCAI

suppressor of cancer cell invasion

chr17_+_33448593 0.057 ENST00000158009.5
FNDC8
fibronectin type III domain containing 8
chr17_-_78450398 0.055 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr16_-_57318566 0.055 ENST00000569059.1
ENST00000219207.5
PLLP

plasmolipin

chr12_+_69864129 0.054 ENST00000547219.1
ENST00000299293.2
ENST00000549921.1
ENST00000550316.1
ENST00000548154.1
ENST00000547414.1
ENST00000550389.1
ENST00000550937.1
ENST00000549092.1
ENST00000550169.1
FRS2









fibroblast growth factor receptor substrate 2









chr6_+_158733692 0.054 ENST00000367094.2
ENST00000367097.3
TULP4

tubby like protein 4

chr6_+_87865262 0.054 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr12_-_48499591 0.054 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1



SUMO1/sentrin specific peptidase 1



chr10_-_72043432 0.053 ENST00000277942.6
NPFFR1
neuropeptide FF receptor 1
chr15_+_57210818 0.053 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12




transcription factor 12




chr16_-_18937726 0.053 ENST00000389467.3
ENST00000446231.2
SMG1

SMG1 phosphatidylinositol 3-kinase-related kinase

chr17_-_27916621 0.053 ENST00000225394.3
GIT1
G protein-coupled receptor kinase interacting ArfGAP 1
chr22_+_41697520 0.053 ENST00000352645.4
ZC3H7B
zinc finger CCCH-type containing 7B
chr11_+_33278811 0.053 ENST00000303296.4
ENST00000379016.3
HIPK3

homeodomain interacting protein kinase 3

chr2_-_100721178 0.051 ENST00000409236.2
AFF3
AF4/FMR2 family, member 3
chr22_-_41864662 0.051 ENST00000216252.3
PHF5A
PHD finger protein 5A
chr8_-_145559943 0.050 ENST00000332135.4
SCRT1
scratch family zinc finger 1
chr3_+_138066539 0.049 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr22_+_40573921 0.049 ENST00000454349.2
ENST00000335727.9
TNRC6B

trinucleotide repeat containing 6B

chr6_+_136172820 0.049 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr16_+_50187556 0.048 ENST00000561678.1
ENST00000357464.3
PAPD5

PAP associated domain containing 5

chr11_+_68228186 0.047 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
PPP6R3












protein phosphatase 6, regulatory subunit 3












chr5_-_115910630 0.047 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr20_-_40247133 0.046 ENST00000373233.3
ENST00000309279.7
CHD6

chromodomain helicase DNA binding protein 6

chr3_+_38495333 0.046 ENST00000352511.4
ACVR2B
activin A receptor, type IIB
chr9_-_37576226 0.045 ENST00000432825.2
FBXO10
F-box protein 10
chr20_-_982904 0.045 ENST00000217260.4
ENST00000400634.2
RSPO4

R-spondin 4

chr1_+_22889953 0.045 ENST00000374644.4
ENST00000166244.3
ENST00000538803.1
EPHA8


EPH receptor A8


chr17_+_38219063 0.044 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
THRA


thyroid hormone receptor, alpha


chr3_-_136471204 0.044 ENST00000480733.1
ENST00000383202.2
ENST00000236698.5
ENST00000434713.2
STAG1



stromal antigen 1



chr17_-_58603568 0.044 ENST00000083182.3
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr9_+_115249100 0.043 ENST00000337530.6
ENST00000374244.3
ENST00000536272.1
KIAA1958


KIAA1958


chr15_-_79237433 0.042 ENST00000220166.5
CTSH
cathepsin H
chr2_+_231729615 0.042 ENST00000326427.6
ENST00000335005.6
ENST00000326407.6
ITM2C


integral membrane protein 2C


chr10_+_25463951 0.042 ENST00000376351.3
GPR158
G protein-coupled receptor 158
chr3_+_93781728 0.040 ENST00000314622.4
NSUN3
NOP2/Sun domain family, member 3
chr1_+_26438289 0.040 ENST00000374271.4
ENST00000374269.1
PDIK1L

PDLIM1 interacting kinase 1 like

chr19_+_3880581 0.040 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ATCAY


ataxia, cerebellar, Cayman type


chr9_+_108456800 0.040 ENST00000434214.1
ENST00000374692.3
TMEM38B

transmembrane protein 38B

chr6_-_46293378 0.039 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr12_-_498620 0.039 ENST00000399788.2
ENST00000382815.4
KDM5A

lysine (K)-specific demethylase 5A

chr2_+_48010221 0.038 ENST00000234420.5
MSH6
mutS homolog 6
chr1_-_155211017 0.038 ENST00000536770.1
ENST00000368373.3
GBA

glucosidase, beta, acid

chr1_-_224033596 0.036 ENST00000391878.2
ENST00000343537.7
TP53BP2

tumor protein p53 binding protein, 2

chr1_+_110693103 0.036 ENST00000331565.4
SLC6A17
solute carrier family 6 (neutral amino acid transporter), member 17

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.4 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.3 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 0.1 GO:0071335 fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) submandibular salivary gland formation(GO:0060661) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 0.2 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.5 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.0 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.0 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.0 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956) negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.0 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0060033 anatomical structure regression(GO:0060033)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 0.3 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0017057 glucose-6-phosphate dehydrogenase activity(GO:0004345) 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME_REGULATION_OF_KIT_SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels