Motif ID: GATA5

Z-value: 0.519


Transcription factors associated with GATA5:

Gene SymbolEntrez IDGene Name
GATA5 ENSG00000130700.6 GATA5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GATA5hg19_v2_chr20_-_61051026_61051057-0.472.0e-02Click!


Activity profile for motif GATA5.

activity profile for motif GATA5


Sorted Z-values histogram for motif GATA5

Sorted Z-values for motif GATA5



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_110723134 2.090 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr4_-_110723194 2.036 ENST00000394635.3
CFI
complement factor I
chr4_-_110723335 1.906 ENST00000394634.2
CFI
complement factor I
chr10_+_118187379 1.300 ENST00000369230.3
PNLIPRP3
pancreatic lipase-related protein 3
chr4_+_72897521 1.288 ENST00000308744.6
ENST00000344413.5
NPFFR2

neuropeptide FF receptor 2

chr17_+_1633755 0.992 ENST00000545662.1
WDR81
WD repeat domain 81
chr6_-_32557610 0.887 ENST00000360004.5
HLA-DRB1
major histocompatibility complex, class II, DR beta 1
chr1_+_79115503 0.877 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44


interferon-induced protein 44


chr8_+_40010989 0.692 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr1_+_104159999 0.609 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr5_+_140227048 0.606 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr6_+_31916733 0.557 ENST00000483004.1
CFB
complement factor B
chr5_+_140261703 0.477 ENST00000409494.1
ENST00000289272.2
PCDHA13

protocadherin alpha 13

chr10_+_7745232 0.443 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr6_+_42018614 0.442 ENST00000465926.1
ENST00000482432.1
TAF8

TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa

chr1_-_108743471 0.436 ENST00000569674.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr10_+_7745303 0.398 ENST00000429820.1
ENST00000379587.4
ITIH2

inter-alpha-trypsin inhibitor heavy chain 2

chr19_-_52133588 0.380 ENST00000570106.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr6_-_32908765 0.376 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr1_+_86934526 0.356 ENST00000394711.1
CLCA1
chloride channel accessory 1
chr7_-_123197733 0.346 ENST00000470123.1
ENST00000471770.1
NDUFA5

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5

chr10_+_103911926 0.337 ENST00000605788.1
ENST00000405356.1
NOLC1

nucleolar and coiled-body phosphoprotein 1

chr7_+_134331550 0.328 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
BPGM


2,3-bisphosphoglycerate mutase


chr6_+_32709119 0.317 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr6_-_52710893 0.316 ENST00000284562.2
GSTA5
glutathione S-transferase alpha 5
chr9_+_91933407 0.315 ENST00000375807.3
ENST00000339901.4
SECISBP2

SECIS binding protein 2

chr4_+_110834033 0.311 ENST00000509793.1
ENST00000265171.5
EGF

epidermal growth factor

chr11_-_33891362 0.305 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr18_+_48918368 0.299 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1




RP11-267C16.1




chr2_+_69201705 0.288 ENST00000377938.2
GKN1
gastrokine 1
chr15_+_41245160 0.283 ENST00000444189.2
ENST00000446533.3
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr15_+_66874502 0.276 ENST00000558797.1
RP11-321F6.1
HCG2003567; Uncharacterized protein
chr17_-_39203519 0.266 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chr6_+_126102292 0.257 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr2_-_109605663 0.248 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR


ectodysplasin A receptor


chr5_+_140602904 0.245 ENST00000515856.2
ENST00000239449.4
PCDHB14

protocadherin beta 14

chr16_+_67927147 0.228 ENST00000291041.5
PSKH1
protein serine kinase H1
chr9_-_70490107 0.228 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5




COBW domain containing 5




chr8_+_20831460 0.222 ENST00000522604.1
RP11-421P23.1
RP11-421P23.1
chrX_+_105192423 0.220 ENST00000540278.1
NRK
Nik related kinase
chr19_+_35820064 0.214 ENST00000341773.6
ENST00000600131.1
ENST00000270311.6
ENST00000595780.1
ENST00000597916.1
ENST00000593867.1
ENST00000600424.1
ENST00000599811.1
ENST00000536635.2
ENST00000085219.5
ENST00000544992.2
ENST00000419549.2
CD22











CD22 molecule











chr20_+_44258165 0.213 ENST00000372643.3
WFDC10A
WAP four-disulfide core domain 10A
chrX_-_65253506 0.208 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr10_-_93669233 0.201 ENST00000311575.5
FGFBP3
fibroblast growth factor binding protein 3
chr13_+_27844464 0.194 ENST00000241463.4
RASL11A
RAS-like, family 11, member A
chr6_-_154677900 0.193 ENST00000265198.4
ENST00000520261.1
IPCEF1

interaction protein for cytohesin exchange factors 1

chr10_+_53806501 0.185 ENST00000373975.2
PRKG1
protein kinase, cGMP-dependent, type I
chr11_-_61734599 0.183 ENST00000532601.1
FTH1
ferritin, heavy polypeptide 1
chr12_+_101988627 0.178 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1








myosin binding protein C, slow type








chr4_-_70518941 0.174 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1

UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus

UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr16_-_33647696 0.171 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9

Uncharacterized protein

chr16_+_56485402 0.170 ENST00000566157.1
ENST00000562150.1
ENST00000561646.1
ENST00000568397.1
OGFOD1



2-oxoglutarate and iron-dependent oxygenase domain containing 1



chr17_-_72772462 0.169 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9







N-acetyltransferase 9 (GCN5-related, putative)







chr6_+_131571535 0.168 ENST00000474850.2
AKAP7
A kinase (PRKA) anchor protein 7
chr5_+_179125368 0.165 ENST00000502296.1
ENST00000504734.1
ENST00000415618.2
CANX


calnexin


chr13_+_77522632 0.165 ENST00000377462.1
IRG1
immunoresponsive 1 homolog (mouse)
chr3_+_169755715 0.164 ENST00000355897.5
GPR160
G protein-coupled receptor 160
chr1_-_157014865 0.160 ENST00000361409.2
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
chr20_+_32254286 0.157 ENST00000330271.4
ACTL10
actin-like 10
chr12_-_54582655 0.154 ENST00000504338.1
ENST00000514685.1
ENST00000504797.1
ENST00000513838.1
ENST00000505128.1
ENST00000337581.3
ENST00000503306.1
ENST00000243112.5
ENST00000514196.1
ENST00000506169.1
ENST00000507904.1
ENST00000508394.2
SMUG1











single-strand-selective monofunctional uracil-DNA glycosylase 1











chr2_+_191792376 0.151 ENST00000409428.1
ENST00000409215.1
GLS

glutaminase

chr16_+_25228242 0.150 ENST00000219660.5
AQP8
aquaporin 8
chr1_+_171454639 0.148 ENST00000392078.3
ENST00000426496.2
PRRC2C

proline-rich coiled-coil 2C

chr1_+_207277590 0.147 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr6_+_31783291 0.145 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
HSPA1A


heat shock 70kDa protein 1A


chr11_-_11747257 0.143 ENST00000601641.1
AC131935.1
AC131935.1
chr8_+_38065104 0.143 ENST00000521311.1
BAG4
BCL2-associated athanogene 4
chr2_+_216974020 0.140 ENST00000392132.2
ENST00000417391.1
XRCC5

X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

chr15_-_20193370 0.140 ENST00000558565.2
IGHV3OR15-7
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr11_+_118754475 0.135 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chrX_-_72097698 0.133 ENST00000373530.1
DMRTC1
DMRT-like family C1
chrX_+_52235228 0.133 ENST00000518075.1
XAGE1B
X antigen family, member 1B
chr5_+_179125907 0.132 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
CANX








calnexin








chr3_+_141144963 0.129 ENST00000510726.1
ZBTB38
zinc finger and BTB domain containing 38
chr12_-_9102549 0.129 ENST00000000412.3
M6PR
mannose-6-phosphate receptor (cation dependent)
chr3_+_108541545 0.129 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr2_+_102615416 0.126 ENST00000393414.2
IL1R2
interleukin 1 receptor, type II
chr3_+_108541608 0.125 ENST00000426646.1
TRAT1
T cell receptor associated transmembrane adaptor 1
chr13_-_46756351 0.124 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_+_57881740 0.120 ENST00000262027.5
ENST00000315473.5
MARS

methionyl-tRNA synthetase

chr19_-_14992264 0.120 ENST00000327462.2
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr3_+_141144954 0.120 ENST00000441582.2
ENST00000321464.5
ZBTB38

zinc finger and BTB domain containing 38

chrX_+_1734051 0.116 ENST00000381229.4
ENST00000381233.3
ASMT

acetylserotonin O-methyltransferase

chr11_+_114310164 0.116 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
REXO2


RNA exonuclease 2


chr12_+_75874580 0.114 ENST00000456650.3
GLIPR1
GLI pathogenesis-related 1
chr6_-_29395509 0.113 ENST00000377147.2
OR11A1
olfactory receptor, family 11, subfamily A, member 1
chr20_-_29994007 0.111 ENST00000376314.2
DEFB121
defensin, beta 121
chr1_-_160681593 0.110 ENST00000368045.3
ENST00000368046.3
CD48

CD48 molecule

chr17_+_45908974 0.110 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chrX_+_1733876 0.107 ENST00000381241.3
ASMT
acetylserotonin O-methyltransferase
chr19_-_56110859 0.106 ENST00000221665.3
ENST00000592585.1
FIZ1

FLT3-interacting zinc finger 1

chr1_+_171454659 0.105 ENST00000367742.3
ENST00000338920.4
PRRC2C

proline-rich coiled-coil 2C

chr1_-_203274418 0.103 ENST00000457348.1
RP11-134P9.1
long intergenic non-protein coding RNA 1136
chr1_+_57320437 0.102 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr8_-_18666360 0.102 ENST00000286485.8
PSD3
pleckstrin and Sec7 domain containing 3
chr16_-_28503357 0.101 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3







ceroid-lipofuscinosis, neuronal 3







chr10_+_43916052 0.099 ENST00000442526.2
RP11-517P14.2
RP11-517P14.2
chr9_-_35650900 0.099 ENST00000259608.3
SIT1
signaling threshold regulating transmembrane adaptor 1
chr16_-_87466740 0.097 ENST00000561928.1
ZCCHC14
zinc finger, CCHC domain containing 14
chr2_+_102928009 0.093 ENST00000404917.2
ENST00000447231.1
IL1RL1

interleukin 1 receptor-like 1

chr14_-_45252031 0.091 ENST00000556405.1
RP11-398E10.1
RP11-398E10.1
chr20_+_22034809 0.091 ENST00000449427.1
RP11-125P18.1
RP11-125P18.1
chr3_-_156878540 0.089 ENST00000461804.1
CCNL1
cyclin L1
chr5_-_158526693 0.089 ENST00000380654.4
EBF1
early B-cell factor 1
chrM_+_10053 0.087 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr6_-_33290580 0.087 ENST00000446511.1
ENST00000446403.1
ENST00000414083.2
ENST00000266000.6
ENST00000374542.5
DAXX




death-domain associated protein




chr6_-_86099898 0.087 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chr5_+_140753444 0.085 ENST00000517434.1
PCDHGA6
protocadherin gamma subfamily A, 6
chr8_+_132952112 0.085 ENST00000520362.1
ENST00000519656.1
EFR3A

EFR3 homolog A (S. cerevisiae)

chr22_+_17956618 0.083 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr11_+_114310102 0.078 ENST00000265881.5
REXO2
RNA exonuclease 2
chr1_+_150229554 0.078 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr1_-_182921119 0.077 ENST00000423786.1
SHCBP1L
SHC SH2-domain binding protein 1-like
chr9_-_6645628 0.075 ENST00000321612.6
GLDC
glycine dehydrogenase (decarboxylating)
chr16_-_69373396 0.075 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8


component of oligomeric golgi complex 8


chr12_-_9268707 0.074 ENST00000318602.7
A2M
alpha-2-macroglobulin
chr19_-_14889349 0.073 ENST00000315576.3
ENST00000392967.2
ENST00000346057.1
ENST00000353876.1
ENST00000353005.1
EMR2




egf-like module containing, mucin-like, hormone receptor-like 2




chr10_-_114206649 0.070 ENST00000369404.3
ENST00000369405.3
ZDHHC6

zinc finger, DHHC-type containing 6

chr13_-_107214291 0.067 ENST00000375926.1
ARGLU1
arginine and glutamate rich 1
chr10_+_15085936 0.067 ENST00000378217.3
OLAH
oleoyl-ACP hydrolase
chr10_+_35484053 0.067 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
CREM



cAMP responsive element modulator



chr1_+_156123318 0.066 ENST00000368285.3
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_+_31366536 0.065 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr3_+_184080387 0.064 ENST00000455712.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr11_+_18433840 0.064 ENST00000541669.1
ENST00000280704.4
LDHC

lactate dehydrogenase C

chrX_-_13338518 0.064 ENST00000380622.2
ATXN3L
ataxin 3-like
chr6_-_117150198 0.063 ENST00000310357.3
ENST00000368549.3
ENST00000530250.1
GPRC6A


G protein-coupled receptor, family C, group 6, member A


chr16_+_77224732 0.062 ENST00000569610.1
ENST00000248248.3
ENST00000567291.1
ENST00000320859.6
ENST00000563612.1
ENST00000563279.1
MON1B





MON1 secretory trafficking family member B





chr3_+_46283916 0.061 ENST00000395940.2
CCR3
chemokine (C-C motif) receptor 3
chrX_+_30260054 0.060 ENST00000378982.2
MAGEB4
melanoma antigen family B, 4
chr11_+_57308979 0.060 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr14_-_24553834 0.060 ENST00000397002.2
NRL
neural retina leucine zipper
chrM_+_10758 0.060 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr20_-_44207965 0.059 ENST00000357199.4
ENST00000289953.2
WFDC8

WAP four-disulfide core domain 8

chr17_+_41323204 0.059 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
NBR1



neighbor of BRCA1 gene 1



chrX_+_30261847 0.059 ENST00000378981.3
ENST00000397550.1
MAGEB1

melanoma antigen family B, 1

chr2_-_47143160 0.058 ENST00000409800.1
ENST00000409218.1
MCFD2

multiple coagulation factor deficiency 2

chr10_+_15085895 0.057 ENST00000378228.3
OLAH
oleoyl-ACP hydrolase
chr3_+_46283863 0.057 ENST00000545097.1
ENST00000541018.1
CCR3

chemokine (C-C motif) receptor 3

chr9_-_123239632 0.054 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr3_+_57881966 0.053 ENST00000495364.1
SLMAP
sarcolemma associated protein
chr2_+_166150541 0.052 ENST00000283256.6
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr15_-_54025300 0.050 ENST00000559418.1
WDR72
WD repeat domain 72
chr10_+_60028818 0.050 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr8_+_9046503 0.047 ENST00000512942.2
RP11-10A14.5
RP11-10A14.5
chr3_-_182817297 0.047 ENST00000539926.1
ENST00000476176.1
MCCC1

methylcrotonoyl-CoA carboxylase 1 (alpha)

chr5_-_150537279 0.046 ENST00000517486.1
ENST00000377751.5
ENST00000356496.5
ENST00000521512.1
ENST00000517757.1
ENST00000354546.5
ANXA6





annexin A6





chr2_+_102927962 0.046 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1

IL18R1
interleukin 1 receptor-like 1

interleukin 18 receptor 1
chr12_+_62860581 0.044 ENST00000393632.2
ENST00000393630.3
ENST00000280379.6
ENST00000546600.1
ENST00000552738.1
ENST00000393629.2
ENST00000552115.1
MON2






MON2 homolog (S. cerevisiae)






chr7_-_34978980 0.042 ENST00000428054.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr6_-_135271260 0.040 ENST00000265605.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr20_-_61885826 0.040 ENST00000370316.3
NKAIN4
Na+/K+ transporting ATPase interacting 4
chr3_+_193310918 0.039 ENST00000361908.3
ENST00000392438.3
ENST00000361510.2
ENST00000361715.2
ENST00000361828.2
ENST00000361150.2
OPA1





optic atrophy 1 (autosomal dominant)





chr19_-_14952689 0.038 ENST00000248058.1
OR7A10
olfactory receptor, family 7, subfamily A, member 10
chr6_-_135271219 0.038 ENST00000367847.2
ENST00000367845.2
ALDH8A1

aldehyde dehydrogenase 8 family, member A1

chr2_-_136594740 0.037 ENST00000264162.2
LCT
lactase
chr1_-_158656488 0.036 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr2_+_201997676 0.036 ENST00000462763.1
ENST00000479953.2
CFLAR

CASP8 and FADD-like apoptosis regulator

chr7_+_16793160 0.036 ENST00000262067.4
TSPAN13
tetraspanin 13
chr4_-_100575781 0.036 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr16_+_31366455 0.033 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chrX_+_11777671 0.033 ENST00000380693.3
ENST00000380692.2
MSL3

male-specific lethal 3 homolog (Drosophila)

chr14_-_82000140 0.032 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L


sel-1 suppressor of lin-12-like (C. elegans)


chr12_-_57882577 0.031 ENST00000393797.2
ARHGAP9
Rho GTPase activating protein 9
chr5_+_38445641 0.031 ENST00000397210.3
ENST00000506135.1
ENST00000508131.1
EGFLAM


EGF-like, fibronectin type III and laminin G domains


chr2_+_96331830 0.030 ENST00000425887.2
AC008268.1
AC008268.1
chr18_-_5419797 0.030 ENST00000542146.1
ENST00000427684.2
EPB41L3

erythrocyte membrane protein band 4.1-like 3

chr15_-_22082822 0.029 ENST00000439682.1
POTEB
POTE ankyrin domain family, member B
chr17_-_61996160 0.029 ENST00000458650.2
ENST00000351388.4
ENST00000323322.5
GH1


growth hormone 1


chr17_+_36908984 0.029 ENST00000225426.4
ENST00000579088.1
PSMB3

proteasome (prosome, macropain) subunit, beta type, 3

chr3_-_108476231 0.029 ENST00000295755.6
RETNLB
resistin like beta
chr8_-_7243080 0.029 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr3_+_44916098 0.027 ENST00000296125.4
TGM4
transglutaminase 4
chr15_-_21071643 0.025 ENST00000454856.4
POTEB2
POTE ankyrin domain family, member B2
chr13_+_107029084 0.025 ENST00000444865.1
LINC00460
long intergenic non-protein coding RNA 460
chr2_-_106013400 0.024 ENST00000409807.1
FHL2
four and a half LIM domains 2
chr12_-_102455902 0.024 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr1_-_11918988 0.022 ENST00000376468.3
NPPB
natriuretic peptide B
chr12_-_102455846 0.021 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr8_-_97247759 0.021 ENST00000518406.1
ENST00000523920.1
ENST00000287022.5
UQCRB


ubiquinol-cytochrome c reductase binding protein


chr19_+_42580274 0.020 ENST00000359044.4
ZNF574
zinc finger protein 574
chr8_-_6875778 0.020 ENST00000327857.2
ENST00000535841.1
DEFA3
DEFA1B
defensin, alpha 3, neutrophil-specific
defensin, alpha 1B
chr8_-_6837602 0.020 ENST00000382692.2
DEFA1
defensin, alpha 1
chr3_+_155860751 0.019 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr10_-_49482907 0.018 ENST00000374201.3
ENST00000407470.4
FRMPD2

FERM and PDZ domain containing 2

chr12_-_45270077 0.018 ENST00000551601.1
ENST00000549027.1
ENST00000452445.2
NELL2


NEL-like 2 (chicken)


chr5_-_58652788 0.018 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_121461097 0.018 ENST00000527934.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr6_-_55739542 0.017 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chr14_-_106781017 0.015 ENST00000390612.2
IGHV4-28
immunoglobulin heavy variable 4-28
chr5_-_75919217 0.014 ENST00000504899.1
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr3_+_178276488 0.013 ENST00000432997.1
ENST00000455865.1
KCNMB2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr18_+_13611763 0.013 ENST00000585931.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr1_-_27481401 0.012 ENST00000263980.3
SLC9A1
solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
chr12_-_45270151 0.012 ENST00000429094.2
NELL2
NEL-like 2 (chicken)
chr11_-_124180733 0.011 ENST00000357821.2
OR8D1
olfactory receptor, family 8, subfamily D, member 1
chr12_-_45269430 0.011 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr17_+_53344945 0.009 ENST00000575345.1
HLF
hepatic leukemia factor
chr2_-_40006289 0.008 ENST00000260619.6
ENST00000454352.2
THUMPD2

THUMP domain containing 2

chr2_-_209054709 0.005 ENST00000449053.1
ENST00000451346.1
ENST00000341287.4
C2orf80


chromosome 2 open reading frame 80



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.1 0.7 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.2 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.3 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 6.7 GO:0030449 regulation of complement activation(GO:0030449)
0.0 1.3 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.4 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:2001252 positive regulation of chromosome organization(GO:2001252)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.0 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016160 amylase activity(GO:0016160)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 6.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.2 GO:0031628 opioid receptor binding(GO:0031628)
0.0 1.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.3 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 1.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0016296 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 ST_G_ALPHA_S_PATHWAY G alpha s Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.7 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 0.6 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.1 REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME_CALNEXIN_CALRETICULIN_CYCLE Genes involved in Calnexin/calreticulin cycle