Motif ID: FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
Z-value: 0.959
Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
FOXD1 | ENSG00000251493.2 | FOXD1 |
FOXG1 | ENSG00000176165.7 | FOXG1 |
FOXO1 | ENSG00000150907.6 | FOXO1 |
FOXO6 | ENSG00000204060.4 | FOXO6 |
FOXP1 | ENSG00000114861.14 | FOXP1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
FOXP1 | hg19_v2_chr3_-_71632894_71632909 | -0.19 | 3.8e-01 | Click! |
FOXG1 | hg19_v2_chr14_+_29236269_29236287, hg19_v2_chr14_+_29234870_29235050 | 0.15 | 4.8e-01 | Click! |
FOXO6 | hg19_v2_chr1_+_41827594_41827594 | -0.07 | 7.3e-01 | Click! |
FOXO1 | hg19_v2_chr13_-_41240717_41240735 | -0.03 | 8.7e-01 | Click! |
FOXD1 | hg19_v2_chr5_-_72744336_72744359 | 0.03 | 8.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.7 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
0.5 | 1.4 | GO:0035623 | regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623) |
0.4 | 5.4 | GO:0033227 | dsRNA transport(GO:0033227) |
0.4 | 1.4 | GO:0006210 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
0.3 | 1.0 | GO:0033242 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
0.3 | 1.0 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
0.3 | 2.0 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
0.3 | 0.7 | GO:0097325 | melanocyte proliferation(GO:0097325) |
0.3 | 1.9 | GO:0001712 | ectodermal cell fate commitment(GO:0001712) |
0.3 | 1.6 | GO:0030070 | insulin processing(GO:0030070) |
0.3 | 1.3 | GO:0044501 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
0.3 | 1.5 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.3 | 1.2 | GO:0010157 | response to chlorate(GO:0010157) |
0.3 | 1.2 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.3 | 0.9 | GO:0002276 | basophil activation involved in immune response(GO:0002276) |
0.3 | 1.4 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
0.3 | 0.8 | GO:0045658 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
0.2 | 1.7 | GO:0097338 | response to clozapine(GO:0097338) |
0.2 | 1.1 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
0.2 | 0.6 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
0.2 | 0.6 | GO:0072186 | metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) |
0.2 | 0.6 | GO:0090294 | nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250) |
0.2 | 1.8 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.2 | 1.1 | GO:1904721 | negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
0.2 | 0.6 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
0.2 | 3.4 | GO:0090179 | planar cell polarity pathway involved in neural tube closure(GO:0090179) |
0.2 | 0.7 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
0.2 | 1.0 | GO:0006196 | AMP catabolic process(GO:0006196) |
0.2 | 0.5 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
0.2 | 1.7 | GO:0097167 | circadian regulation of translation(GO:0097167) |
0.2 | 2.9 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.2 | 0.8 | GO:0032455 | nerve growth factor processing(GO:0032455) |
0.2 | 1.6 | GO:0098734 | macromolecule depalmitoylation(GO:0098734) |
0.2 | 0.6 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
0.2 | 0.5 | GO:1904298 | positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317) |
0.1 | 0.1 | GO:0060734 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) |
0.1 | 0.4 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
0.1 | 0.8 | GO:0060005 | vestibular reflex(GO:0060005) |
0.1 | 1.0 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
0.1 | 1.1 | GO:0044254 | multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) |
0.1 | 0.7 | GO:0061146 | Peyer's patch morphogenesis(GO:0061146) |
0.1 | 1.2 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
0.1 | 0.6 | GO:0048861 | leukemia inhibitory factor signaling pathway(GO:0048861) |
0.1 | 0.5 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
0.1 | 0.1 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
0.1 | 1.7 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.1 | 0.4 | GO:1902869 | commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) regulation of amacrine cell differentiation(GO:1902869) |
0.1 | 0.5 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
0.1 | 1.7 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
0.1 | 0.7 | GO:0090131 | mesenchyme migration(GO:0090131) |
0.1 | 0.4 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
0.1 | 0.8 | GO:0071461 | cellular response to redox state(GO:0071461) |
0.1 | 0.3 | GO:2000910 | negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910) |
0.1 | 2.7 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
0.1 | 0.3 | GO:0007518 | myoblast fate determination(GO:0007518) |
0.1 | 0.5 | GO:1904016 | response to Thyroglobulin triiodothyronine(GO:1904016) |
0.1 | 0.6 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
0.1 | 0.4 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.1 | 0.3 | GO:0030037 | actin filament reorganization involved in cell cycle(GO:0030037) |
0.1 | 0.3 | GO:0099552 | trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) |
0.1 | 2.4 | GO:0035855 | megakaryocyte development(GO:0035855) |
0.1 | 0.5 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
0.1 | 0.2 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
0.1 | 1.0 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
0.1 | 0.5 | GO:0009597 | detection of virus(GO:0009597) |
0.1 | 0.8 | GO:0021759 | globus pallidus development(GO:0021759) |
0.1 | 0.5 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.1 | 0.9 | GO:0034392 | negative regulation of smooth muscle cell apoptotic process(GO:0034392) |
0.1 | 0.2 | GO:1901876 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
0.1 | 0.3 | GO:0015917 | aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) regulation of high-density lipoprotein particle assembly(GO:0090107) |
0.1 | 0.4 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
0.1 | 0.1 | GO:0014034 | neural crest cell fate commitment(GO:0014034) |
0.1 | 0.2 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
0.1 | 0.2 | GO:1900108 | negative regulation of nodal signaling pathway(GO:1900108) |
0.1 | 0.2 | GO:2000974 | inhibition of neuroepithelial cell differentiation(GO:0002085) trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974) |
0.1 | 0.3 | GO:0014878 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) |
0.1 | 1.7 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
0.1 | 0.7 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
0.1 | 0.5 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.1 | 0.4 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
0.1 | 0.2 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
0.1 | 1.2 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
0.1 | 1.0 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.1 | 0.5 | GO:0002667 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
0.1 | 0.2 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
0.1 | 0.2 | GO:1901207 | regulation of heart looping(GO:1901207) |
0.1 | 0.1 | GO:0010159 | specification of organ position(GO:0010159) |
0.1 | 0.3 | GO:0035864 | response to potassium ion(GO:0035864) |
0.1 | 0.4 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 2.9 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
0.1 | 0.8 | GO:0035878 | nail development(GO:0035878) |
0.1 | 0.4 | GO:0036486 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) |
0.1 | 0.5 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.1 | 0.3 | GO:0033078 | extrathymic T cell differentiation(GO:0033078) |
0.1 | 1.6 | GO:0048268 | clathrin coat assembly(GO:0048268) |
0.1 | 0.3 | GO:0014028 | notochord formation(GO:0014028) |
0.1 | 0.2 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
0.1 | 0.2 | GO:0071676 | negative regulation of mononuclear cell migration(GO:0071676) |
0.1 | 0.5 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.0 | 0.4 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.0 | 0.2 | GO:0021590 | cerebellum maturation(GO:0021590) cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699) |
0.0 | 0.2 | GO:0018032 | protein amidation(GO:0018032) |
0.0 | 0.3 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
0.0 | 0.8 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
0.0 | 0.2 | GO:0045084 | positive regulation of interleukin-12 biosynthetic process(GO:0045084) |
0.0 | 0.4 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 0.7 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
0.0 | 0.3 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
0.0 | 0.3 | GO:0030805 | regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
0.0 | 0.1 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
0.0 | 0.5 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.2 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
0.0 | 1.1 | GO:0032060 | bleb assembly(GO:0032060) |
0.0 | 0.5 | GO:0030202 | heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210) |
0.0 | 0.1 | GO:0051919 | positive regulation of fibrinolysis(GO:0051919) |
0.0 | 0.2 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
0.0 | 0.3 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
0.0 | 0.1 | GO:0008050 | female courtship behavior(GO:0008050) |
0.0 | 0.3 | GO:0042996 | regulation of Golgi to plasma membrane protein transport(GO:0042996) |
0.0 | 0.2 | GO:0070995 | NADPH oxidation(GO:0070995) |
0.0 | 0.4 | GO:0071763 | nuclear membrane organization(GO:0071763) |
0.0 | 0.2 | GO:1903961 | positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961) |
0.0 | 0.4 | GO:0032782 | bile acid secretion(GO:0032782) |
0.0 | 0.3 | GO:0098501 | polynucleotide dephosphorylation(GO:0098501) |
0.0 | 0.1 | GO:0070352 | positive regulation of white fat cell proliferation(GO:0070352) |
0.0 | 0.3 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
0.0 | 0.3 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
0.0 | 0.3 | GO:0070294 | renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294) |
0.0 | 0.2 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
0.0 | 0.2 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
0.0 | 0.2 | GO:0001692 | histamine metabolic process(GO:0001692) |
0.0 | 1.1 | GO:0042994 | cytoplasmic sequestering of transcription factor(GO:0042994) |
0.0 | 0.2 | GO:0002159 | desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603) |
0.0 | 0.2 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
0.0 | 0.2 | GO:0070885 | negative regulation of calcineurin-NFAT signaling cascade(GO:0070885) |
0.0 | 0.6 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
0.0 | 0.7 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
0.0 | 0.3 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
0.0 | 2.7 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
0.0 | 1.0 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
0.0 | 0.2 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.0 | 0.6 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
0.0 | 0.9 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
0.0 | 0.1 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
0.0 | 0.7 | GO:0007039 | protein catabolic process in the vacuole(GO:0007039) |
0.0 | 0.3 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.0 | 0.1 | GO:0002514 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
0.0 | 0.1 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
0.0 | 0.5 | GO:0033561 | regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436) |
0.0 | 0.3 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
0.0 | 0.1 | GO:0000415 | negative regulation of histone H3-K36 methylation(GO:0000415) |
0.0 | 0.5 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
0.0 | 0.1 | GO:0035063 | nuclear speck organization(GO:0035063) |
0.0 | 0.1 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
0.0 | 1.5 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
0.0 | 0.1 | GO:0098886 | modification of dendritic spine(GO:0098886) |
0.0 | 0.2 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
0.0 | 0.3 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
0.0 | 0.7 | GO:0042730 | fibrinolysis(GO:0042730) |
0.0 | 0.2 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
0.0 | 0.3 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
0.0 | 0.1 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
0.0 | 0.8 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.0 | 0.2 | GO:1903760 | regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) |
0.0 | 0.2 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.0 | 1.4 | GO:0051646 | mitochondrion localization(GO:0051646) |
0.0 | 0.1 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
0.0 | 0.2 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.2 | GO:0006552 | leucine catabolic process(GO:0006552) |
0.0 | 0.1 | GO:0060266 | negative regulation of respiratory burst involved in inflammatory response(GO:0060266) |
0.0 | 0.1 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
0.0 | 2.3 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
0.0 | 0.1 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.0 | 0.1 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
0.0 | 0.6 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
0.0 | 0.1 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
0.0 | 0.5 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
0.0 | 0.1 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
0.0 | 0.6 | GO:0001569 | patterning of blood vessels(GO:0001569) |
0.0 | 0.0 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
0.0 | 0.1 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
0.0 | 0.1 | GO:0032416 | negative regulation of sodium:proton antiporter activity(GO:0032416) |
0.0 | 0.6 | GO:0002076 | osteoblast development(GO:0002076) |
0.0 | 0.2 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.2 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.0 | 0.1 | GO:0044245 | polysaccharide digestion(GO:0044245) |
0.0 | 0.2 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
0.0 | 0.4 | GO:0031061 | negative regulation of histone methylation(GO:0031061) |
0.0 | 0.2 | GO:0007172 | signal complex assembly(GO:0007172) netrin-activated signaling pathway(GO:0038007) |
0.0 | 0.2 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
0.0 | 0.9 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
0.0 | 0.1 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
0.0 | 0.1 | GO:0044791 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
0.0 | 0.2 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
0.0 | 0.3 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.0 | 0.3 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
0.0 | 0.2 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
0.0 | 0.3 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.0 | 0.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
0.0 | 0.5 | GO:0072600 | establishment of protein localization to Golgi(GO:0072600) |
0.0 | 0.1 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.0 | 0.2 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
0.0 | 0.0 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
0.0 | 1.1 | GO:0016266 | O-glycan processing(GO:0016266) |
0.0 | 0.3 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
0.0 | 0.0 | GO:0060353 | regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355) |
0.0 | 0.2 | GO:0036315 | cellular response to sterol(GO:0036315) |
0.0 | 0.3 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.0 | 0.3 | GO:0006853 | carnitine shuttle(GO:0006853) |
0.0 | 0.1 | GO:0070649 | polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649) |
0.0 | 0.1 | GO:0035553 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
0.0 | 0.1 | GO:0010728 | regulation of hydrogen peroxide biosynthetic process(GO:0010728) |
0.0 | 0.1 | GO:0043970 | histone H3-K9 acetylation(GO:0043970) |
0.0 | 0.1 | GO:2000543 | primitive streak formation(GO:0090009) positive regulation of gastrulation(GO:2000543) |
0.0 | 0.1 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
0.0 | 0.1 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
0.0 | 0.0 | GO:0035947 | regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) cellular response to cold(GO:0070417) |
0.0 | 0.1 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
0.0 | 0.2 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
0.0 | 0.2 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
0.0 | 0.1 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
0.0 | 0.6 | GO:0048008 | platelet-derived growth factor receptor signaling pathway(GO:0048008) |
0.0 | 0.1 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
0.0 | 0.7 | GO:0015914 | phospholipid transport(GO:0015914) |
0.0 | 0.0 | GO:0019427 | acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542) |
0.0 | 0.0 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
0.0 | 0.1 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
0.0 | 0.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
0.0 | 0.1 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
0.0 | 0.1 | GO:0003025 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564) |
0.0 | 0.3 | GO:0006582 | melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) |
0.0 | 0.1 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.0 | 0.2 | GO:0035774 | positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
0.2 | 0.7 | GO:0097629 | extrinsic component of omegasome membrane(GO:0097629) |
0.2 | 0.9 | GO:0035838 | growing cell tip(GO:0035838) |
0.2 | 3.0 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.2 | 2.4 | GO:0031209 | SCAR complex(GO:0031209) |
0.2 | 1.2 | GO:0044294 | dendritic growth cone(GO:0044294) |
0.1 | 1.2 | GO:0035976 | AP1 complex(GO:0035976) |
0.1 | 0.4 | GO:1990923 | PET complex(GO:1990923) |
0.1 | 1.4 | GO:0097427 | microtubule bundle(GO:0097427) |
0.1 | 0.6 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
0.1 | 0.5 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
0.1 | 0.3 | GO:0019034 | viral replication complex(GO:0019034) |
0.1 | 1.8 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 1.1 | GO:0030478 | actin cap(GO:0030478) |
0.1 | 0.3 | GO:0031251 | PAN complex(GO:0031251) |
0.1 | 2.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.1 | 0.7 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.1 | 0.7 | GO:0071438 | invadopodium membrane(GO:0071438) |
0.1 | 0.4 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.1 | 0.2 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
0.1 | 0.2 | GO:0030658 | transport vesicle membrane(GO:0030658) |
0.1 | 1.9 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.1 | 1.8 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.1 | 0.2 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.0 | 0.3 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
0.0 | 0.5 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.0 | 0.5 | GO:0032426 | stereocilium tip(GO:0032426) |
0.0 | 2.3 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 0.1 | GO:0070939 | Dsl1p complex(GO:0070939) |
0.0 | 0.1 | GO:0097444 | spine apparatus(GO:0097444) |
0.0 | 0.2 | GO:1990130 | Iml1 complex(GO:1990130) |
0.0 | 0.6 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
0.0 | 0.5 | GO:0035253 | ciliary rootlet(GO:0035253) |
0.0 | 1.0 | GO:0097228 | sperm principal piece(GO:0097228) |
0.0 | 0.3 | GO:0036157 | outer dynein arm(GO:0036157) |
0.0 | 0.1 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
0.0 | 1.5 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 0.1 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
0.0 | 1.1 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.0 | 0.8 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.0 | 0.3 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.0 | 0.6 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.0 | 0.3 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.0 | 0.1 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
0.0 | 0.3 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.0 | 0.2 | GO:0005610 | laminin-5 complex(GO:0005610) |
0.0 | 0.1 | GO:0098855 | HCN channel complex(GO:0098855) |
0.0 | 0.2 | GO:0014802 | terminal cisterna(GO:0014802) |
0.0 | 0.5 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.0 | 0.1 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
0.0 | 0.2 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
0.0 | 0.1 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
0.0 | 0.3 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
0.0 | 0.3 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 0.3 | GO:0071437 | invadopodium(GO:0071437) |
0.0 | 0.2 | GO:0043219 | lateral loop(GO:0043219) |
0.0 | 2.2 | GO:0070821 | tertiary granule membrane(GO:0070821) |
0.0 | 0.1 | GO:0032173 | septin ring(GO:0005940) septin collar(GO:0032173) |
0.0 | 0.1 | GO:0061700 | Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700) |
0.0 | 0.1 | GO:0071817 | MMXD complex(GO:0071817) |
0.0 | 0.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.0 | 0.4 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.0 | 0.3 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
0.0 | 2.0 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 7.7 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
0.0 | 0.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 1.1 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
0.0 | 2.5 | GO:0055037 | recycling endosome(GO:0055037) |
0.0 | 0.3 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.0 | 0.5 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 4.5 | GO:0010008 | endosome membrane(GO:0010008) |
0.0 | 0.5 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
0.0 | 0.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
0.0 | 0.3 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.0 | 0.2 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
0.0 | 0.1 | GO:0031519 | PcG protein complex(GO:0031519) |
0.0 | 0.2 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 0.5 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 1.4 | GO:0043202 | lysosomal lumen(GO:0043202) |
0.0 | 0.2 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
0.0 | 0.4 | GO:0005921 | gap junction(GO:0005921) |
0.0 | 0.1 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
0.0 | 0.5 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 0.0 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.0 | 0.3 | GO:0032982 | myosin filament(GO:0032982) |
0.0 | 0.3 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
0.0 | 0.1 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.0 | 1.9 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 5.4 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
0.8 | 2.4 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.5 | 1.4 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
0.3 | 1.0 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
0.3 | 0.8 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.2 | 2.7 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
0.2 | 0.9 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
0.2 | 0.6 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
0.2 | 1.7 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.2 | 1.9 | GO:0008142 | oxysterol binding(GO:0008142) |
0.2 | 0.6 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) |
0.2 | 1.2 | GO:0005119 | smoothened binding(GO:0005119) |
0.2 | 1.2 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.2 | 0.6 | GO:1902122 | chenodeoxycholic acid binding(GO:1902122) |
0.2 | 1.1 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
0.2 | 1.6 | GO:0043426 | MRF binding(GO:0043426) |
0.2 | 1.6 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
0.1 | 0.7 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.1 | 0.5 | GO:0090079 | translation repressor activity, nucleic acid binding(GO:0000900) translation repressor activity(GO:0030371) translation regulator activity(GO:0045182) translation regulator activity, nucleic acid binding(GO:0090079) |
0.1 | 1.4 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.1 | 1.0 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
0.1 | 1.9 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
0.1 | 1.2 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.1 | 1.2 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
0.1 | 0.6 | GO:0042289 | MHC class II protein binding(GO:0042289) |
0.1 | 0.5 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
0.1 | 0.4 | GO:0034584 | piRNA binding(GO:0034584) |
0.1 | 0.4 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
0.1 | 0.5 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.1 | 1.7 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.1 | 3.0 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.1 | 0.7 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
0.1 | 0.5 | GO:0004992 | platelet activating factor receptor activity(GO:0004992) |
0.1 | 0.3 | GO:0050528 | acyloxyacyl hydrolase activity(GO:0050528) |
0.1 | 1.5 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.1 | 0.5 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.1 | 0.3 | GO:0016749 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
0.1 | 0.3 | GO:0098518 | polynucleotide phosphatase activity(GO:0098518) |
0.1 | 0.3 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
0.1 | 0.2 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.1 | 0.3 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
0.1 | 2.1 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.1 | 0.5 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
0.1 | 0.3 | GO:0004949 | cannabinoid receptor activity(GO:0004949) |
0.1 | 0.4 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 1.4 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
0.1 | 0.4 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
0.1 | 0.2 | GO:0008267 | poly-glutamine tract binding(GO:0008267) |
0.1 | 0.5 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.1 | 0.2 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
0.1 | 1.0 | GO:0015643 | toxic substance binding(GO:0015643) |
0.1 | 0.3 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
0.1 | 2.2 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
0.1 | 1.7 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.1 | 0.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.1 | 0.3 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
0.1 | 0.2 | GO:0004938 | alpha2-adrenergic receptor activity(GO:0004938) |
0.1 | 0.8 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
0.0 | 1.4 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
0.0 | 0.2 | GO:0001632 | leukotriene B4 receptor activity(GO:0001632) |
0.0 | 1.5 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 0.2 | GO:0004504 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
0.0 | 0.4 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 0.4 | GO:0043208 | glycosphingolipid binding(GO:0043208) |
0.0 | 6.0 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 0.4 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
0.0 | 0.4 | GO:0015321 | sodium-dependent phosphate transmembrane transporter activity(GO:0015321) |
0.0 | 1.2 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
0.0 | 0.3 | GO:0034046 | poly(G) binding(GO:0034046) |
0.0 | 0.2 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
0.0 | 0.2 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
0.0 | 0.7 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
0.0 | 0.2 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.0 | 1.0 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
0.0 | 0.5 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.0 | 3.1 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
0.0 | 0.1 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
0.0 | 0.5 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
0.0 | 0.7 | GO:0048156 | tau protein binding(GO:0048156) |
0.0 | 0.3 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
0.0 | 0.7 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 1.1 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.0 | 0.9 | GO:0016805 | dipeptidase activity(GO:0016805) |
0.0 | 0.3 | GO:0071253 | connexin binding(GO:0071253) |
0.0 | 0.1 | GO:0016160 | amylase activity(GO:0016160) |
0.0 | 2.3 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
0.0 | 0.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
0.0 | 0.3 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
0.0 | 1.2 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
0.0 | 1.4 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.0 | 0.1 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.0 | 0.3 | GO:0008607 | AMP-activated protein kinase activity(GO:0004679) phosphorylase kinase regulator activity(GO:0008607) |
0.0 | 0.1 | GO:0008513 | acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375) |
0.0 | 0.2 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
0.0 | 0.1 | GO:0004307 | diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307) |
0.0 | 0.1 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
0.0 | 0.3 | GO:0031432 | titin binding(GO:0031432) |
0.0 | 0.3 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
0.0 | 0.1 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.0 | 0.3 | GO:0031702 | angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702) |
0.0 | 2.4 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.0 | 0.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.2 | GO:0016015 | morphogen activity(GO:0016015) |
0.0 | 0.1 | GO:0052593 | tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596) |
0.0 | 0.1 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.0 | 0.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
0.0 | 0.2 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
0.0 | 0.7 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.0 | 0.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.2 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.0 | 0.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.0 | 0.5 | GO:0005521 | lamin binding(GO:0005521) |
0.0 | 1.0 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.0 | 0.8 | GO:0030331 | estrogen receptor binding(GO:0030331) |
0.0 | 0.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.3 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 3.3 | GO:0017137 | Rab GTPase binding(GO:0017137) |
0.0 | 0.2 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.0 | GO:0036134 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
0.0 | 0.6 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 0.1 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
0.0 | 0.3 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.1 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
0.0 | 0.2 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.0 | GO:0004961 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
0.0 | 0.3 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
0.0 | 0.4 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
0.0 | 0.0 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
0.0 | 0.2 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 0.1 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
0.0 | 1.0 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
0.0 | 0.3 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 0.1 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
0.0 | 0.2 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
0.0 | 0.3 | GO:0017160 | Ral GTPase binding(GO:0017160) |
0.0 | 0.2 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
0.0 | 0.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.0 | 0.2 | GO:0034185 | apolipoprotein binding(GO:0034185) |
0.0 | 0.0 | GO:0055077 | gap junction hemi-channel activity(GO:0055077) |
0.0 | 0.1 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 0.2 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
0.0 | 0.1 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.0 | 0.3 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 1.0 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
0.0 | 0.3 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
0.0 | 1.9 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.0 | 0.1 | GO:0004075 | biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374) |
0.0 | 0.4 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 0.3 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
0.0 | 0.1 | GO:0004905 | type I interferon receptor activity(GO:0004905) |
0.0 | 0.2 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
0.0 | 0.1 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
0.0 | 0.4 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
0.0 | 0.7 | GO:0005044 | scavenger receptor activity(GO:0005044) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.8 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.1 | 5.3 | PID_INSULIN_PATHWAY | Insulin Pathway |
0.1 | 1.5 | PID_HEDGEHOG_2PATHWAY | Signaling events mediated by the Hedgehog family |
0.1 | 3.2 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 2.9 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
0.0 | 1.7 | PID_IL3_PATHWAY | IL3-mediated signaling events |
0.0 | 0.8 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
0.0 | 2.2 | PID_SYNDECAN_1_PATHWAY | Syndecan-1-mediated signaling events |
0.0 | 1.2 | PID_RXR_VDR_PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
0.0 | 1.9 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.7 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 3.2 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 1.5 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 0.3 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 1.4 | PID_FOXO_PATHWAY | FoxO family signaling |
0.0 | 0.2 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 1.3 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.0 | 1.2 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
0.0 | 0.5 | PID_P38_ALPHA_BETA_PATHWAY | Regulation of p38-alpha and p38-beta |
0.0 | 0.5 | PID_IGF1_PATHWAY | IGF1 pathway |
0.0 | 0.5 | PID_IL27_PATHWAY | IL27-mediated signaling events |
0.0 | 2.4 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
0.0 | 1.1 | PID_NOTCH_PATHWAY | Notch signaling pathway |
0.0 | 1.1 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.0 | 0.9 | PID_TAP63_PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 0.2 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.0 | 0.6 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.0 | 1.3 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 3.9 | NABA_ECM_REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.0 | 0.4 | PID_MET_PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
0.0 | 1.4 | PID_SMAD2_3NUCLEAR_PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 1.6 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
0.0 | 0.2 | PID_UPA_UPAR_PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.0 | 0.1 | PID_ER_NONGENOMIC_PATHWAY | Plasma membrane estrogen receptor signaling |
0.0 | 0.3 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.4 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.1 | 1.9 | REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
0.1 | 3.8 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
0.1 | 1.3 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
0.1 | 3.4 | REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
0.1 | 1.2 | REACTOME_IL_7_SIGNALING | Genes involved in Interleukin-7 signaling |
0.1 | 1.6 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
0.1 | 1.3 | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | Genes involved in Signalling to p38 via RIT and RIN |
0.0 | 1.3 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 1.4 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 0.9 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.0 | 0.5 | REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
0.0 | 0.0 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
0.0 | 1.0 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.0 | 0.6 | REACTOME_STEROID_HORMONES | Genes involved in Steroid hormones |
0.0 | 2.3 | REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
0.0 | 1.6 | REACTOME_PI3K_AKT_ACTIVATION | Genes involved in PI3K/AKT activation |
0.0 | 0.4 | REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
0.0 | 0.5 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
0.0 | 0.5 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
0.0 | 1.3 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.7 | REACTOME_METABOLISM_OF_PORPHYRINS | Genes involved in Metabolism of porphyrins |
0.0 | 0.7 | REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
0.0 | 0.9 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
0.0 | 0.4 | REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
0.0 | 0.3 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
0.0 | 2.0 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
0.0 | 0.3 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
0.0 | 0.5 | REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | Genes involved in Other semaphorin interactions |
0.0 | 0.7 | REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
0.0 | 0.4 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
0.0 | 0.5 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
0.0 | 0.3 | REACTOME_IL_2_SIGNALING | Genes involved in Interleukin-2 signaling |
0.0 | 1.1 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.7 | REACTOME_LIPOPROTEIN_METABOLISM | Genes involved in Lipoprotein metabolism |
0.0 | 0.1 | REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
0.0 | 1.6 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.0 | 0.2 | REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM | Genes involved in Abacavir transport and metabolism |
0.0 | 0.2 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
0.0 | 0.5 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.2 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 0.4 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.0 | 0.2 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |