Motif ID: FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 0.959


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXP1hg19_v2_chr3_-_71632894_71632909-0.193.8e-01Click!
FOXG1hg19_v2_chr14_+_29236269_29236287,
hg19_v2_chr14_+_29234870_29235050
0.154.8e-01Click!
FOXO6hg19_v2_chr1_+_41827594_41827594-0.077.3e-01Click!
FOXO1hg19_v2_chr13_-_41240717_41240735-0.038.7e-01Click!
FOXD1hg19_v2_chr5_-_72744336_727443590.038.8e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_116654376 7.200 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr2_-_165424973 3.945 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr1_+_152486950 2.834 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr11_+_117049910 2.703 ENST00000431081.2
ENST00000524842.1
SIDT2

SID1 transmembrane family, member 2

chr1_-_201096312 2.252 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr18_+_3449330 1.887 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr17_-_8059638 1.777 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1


period circadian clock 1


chr12_+_96588279 1.777 ENST00000552142.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr15_-_60884706 1.678 ENST00000449337.2
RORA
RAR-related orphan receptor A
chr6_+_101847105 1.666 ENST00000369137.3
ENST00000318991.6
GRIK2

glutamate receptor, ionotropic, kainate 2

chr10_-_101841588 1.616 ENST00000370418.3
CPN1
carboxypeptidase N, polypeptide 1
chr1_-_27816556 1.606 ENST00000536657.1
WASF2
WAS protein family, member 2
chrX_-_106960285 1.588 ENST00000503515.1
ENST00000372397.2
TSC22D3

TSC22 domain family, member 3

chr12_+_13349650 1.527 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1



epithelial membrane protein 1



chr5_+_78532003 1.520 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr19_-_45909585 1.462 ENST00000593226.1
ENST00000418234.2
PPP1R13L

protein phosphatase 1, regulatory subunit 13 like

chr9_-_84303269 1.409 ENST00000418319.1
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr11_-_34535297 1.360 ENST00000532417.1
ELF5
E74-like factor 5 (ets domain transcription factor)
chr1_-_45956800 1.360 ENST00000538496.1
TESK2
testis-specific kinase 2
chr11_+_117049445 1.353 ENST00000324225.4
ENST00000532960.1
SIDT2

SID1 transmembrane family, member 2

chr15_-_70994612 1.310 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA


uveal autoantigen with coiled-coil domains and ankyrin repeats


chr11_+_117049854 1.299 ENST00000278951.7
SIDT2
SID1 transmembrane family, member 2
chr8_+_70404996 1.192 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chr1_+_24645865 1.151 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_24645807 1.139 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr14_+_24583836 1.127 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DCAF11








DDB1 and CUL4 associated factor 11








chr1_+_24646002 1.122 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr3_+_188889737 1.095 ENST00000345063.3
TPRG1
tumor protein p63 regulated 1
chrX_+_135251783 1.078 ENST00000394153.2
FHL1
four and a half LIM domains 1
chrX_+_135251835 1.073 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr7_+_106809406 1.068 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1



HMG-box transcription factor 1



chr11_+_10476851 1.047 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr11_+_33061543 1.043 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1


t-complex 11, testis-specific-like 1


chr6_+_74405501 1.043 ENST00000437994.2
ENST00000422508.2
CD109

CD109 molecule

chr15_-_34629922 1.042 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
SLC12A6



solute carrier family 12 (potassium/chloride transporter), member 6



chr1_+_203651937 1.039 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr11_-_111781610 1.035 ENST00000525823.1
CRYAB
crystallin, alpha B
chr11_-_111781454 1.035 ENST00000533280.1
CRYAB
crystallin, alpha B
chr6_+_74405804 1.029 ENST00000287097.5
CD109
CD109 molecule
chr10_+_111985713 1.014 ENST00000239007.7
MXI1
MAX interactor 1, dimerization protein
chr18_+_28898052 1.012 ENST00000257192.4
DSG1
desmoglein 1
chr9_-_98269699 1.010 ENST00000429896.2
PTCH1
patched 1
chr15_-_34630234 1.006 ENST00000558667.1
ENST00000561120.1
ENST00000559236.1
ENST00000397702.2
SLC12A6



solute carrier family 12 (potassium/chloride transporter), member 6



chr2_-_190044480 0.991 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr4_-_152149033 0.976 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr19_+_12902289 0.951 ENST00000302754.4
JUNB
jun B proto-oncogene
chr14_+_24584508 0.930 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11




DDB1 and CUL4 associated factor 11




chr11_-_111781554 0.911 ENST00000526167.1
ENST00000528961.1
CRYAB

crystallin, alpha B

chr1_+_84630367 0.897 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_151778630 0.890 ENST00000368820.3
LINGO4
leucine rich repeat and Ig domain containing 4
chr7_-_140624499 0.885 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr11_+_34654011 0.878 ENST00000531794.1
EHF
ets homologous factor
chr10_+_99400443 0.874 ENST00000370631.3
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr6_+_32121908 0.852 ENST00000375143.2
ENST00000424499.1
PPT2

palmitoyl-protein thioesterase 2

chr12_-_52779433 0.833 ENST00000257951.3
KRT84
keratin 84
chr10_-_21435488 0.832 ENST00000534331.1
ENST00000529198.1
ENST00000377118.4
C10orf113


chromosome 10 open reading frame 113


chr2_-_134326009 0.821 ENST00000409261.1
ENST00000409213.1
NCKAP5

NCK-associated protein 5

chr5_+_72251857 0.819 ENST00000507345.2
ENST00000512348.1
ENST00000287761.6
FCHO2


FCH domain only 2


chr14_-_36988882 0.812 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr6_+_32121789 0.811 ENST00000437001.2
ENST00000375137.2
PPT2

palmitoyl-protein thioesterase 2

chr12_-_92539614 0.809 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr8_+_126442563 0.808 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr20_+_2082494 0.795 ENST00000246032.3
STK35
serine/threonine kinase 35
chr14_-_74551096 0.792 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr6_-_159466042 0.792 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chr4_+_15376165 0.792 ENST00000382383.3
ENST00000429690.1
C1QTNF7

C1q and tumor necrosis factor related protein 7

chr2_+_70142232 0.785 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr1_-_27816641 0.785 ENST00000430629.2
WASF2
WAS protein family, member 2
chr22_-_31688431 0.776 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr6_-_27880174 0.767 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr5_+_72251793 0.761 ENST00000430046.2
ENST00000341845.6
FCHO2

FCH domain only 2

chr17_+_58755184 0.759 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3


breast carcinoma amplified sequence 3


chr16_+_4421841 0.752 ENST00000304735.3
VASN
vasorin
chr6_+_139094657 0.746 ENST00000332797.6
CCDC28A
coiled-coil domain containing 28A
chrX_+_37865804 0.730 ENST00000297875.2
ENST00000357972.5
SYTL5

synaptotagmin-like 5

chr14_-_24584138 0.717 ENST00000558280.1
ENST00000561028.1
NRL

neural retina leucine zipper

chr10_-_45474237 0.714 ENST00000448778.1
ENST00000298295.3
C10orf10

chromosome 10 open reading frame 10

chr10_-_103578182 0.711 ENST00000439817.1
MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr1_-_45956822 0.707 ENST00000372086.3
ENST00000341771.6
TESK2

testis-specific kinase 2

chr19_+_50380917 0.698 ENST00000535102.2
TBC1D17
TBC1 domain family, member 17
chr20_+_52105495 0.697 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr5_-_150460539 0.688 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1



TNFAIP3 interacting protein 1



chr8_+_26150628 0.677 ENST00000523925.1
ENST00000315985.7
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr16_-_30107491 0.673 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
YPEL3



yippee-like 3 (Drosophila)



chr15_-_34610962 0.672 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr7_+_129906660 0.669 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr12_+_96588143 0.669 ENST00000228741.3
ENST00000547249.1
ELK3

ELK3, ETS-domain protein (SRF accessory protein 2)

chr16_+_86612112 0.665 ENST00000320241.3
FOXL1
forkhead box L1
chr12_+_121416340 0.653 ENST00000257555.6
ENST00000400024.2
HNF1A

HNF1 homeobox A

chrX_-_15619076 0.652 ENST00000252519.3
ACE2
angiotensin I converting enzyme 2
chr1_+_209878182 0.649 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr2_+_132479948 0.649 ENST00000355171.4
C2orf27A
chromosome 2 open reading frame 27A
chr11_-_85780853 0.643 ENST00000531930.1
ENST00000528398.1
PICALM

phosphatidylinositol binding clathrin assembly protein

chr4_+_187148556 0.643 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1



kallikrein B, plasma (Fletcher factor) 1



chr4_-_21950356 0.638 ENST00000447367.2
ENST00000382152.2
KCNIP4

Kv channel interacting protein 4

chr14_-_74551172 0.630 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chrX_+_70316005 0.621 ENST00000374259.3
FOXO4
forkhead box O4
chr1_+_84630645 0.618 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_+_50380682 0.614 ENST00000221543.5
TBC1D17
TBC1 domain family, member 17
chr12_+_121416489 0.613 ENST00000541395.1
ENST00000544413.1
HNF1A

HNF1 homeobox A

chr5_-_38557561 0.612 ENST00000511561.1
LIFR
leukemia inhibitory factor receptor alpha
chr1_+_145438469 0.605 ENST00000369317.4
TXNIP
thioredoxin interacting protein
chr5_-_146435694 0.597 ENST00000356826.3
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr17_-_64225508 0.596 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chrX_+_135252050 0.592 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chr12_-_56352368 0.591 ENST00000549404.1
PMEL
premelanosome protein
chr5_-_150460914 0.588 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr11_-_34535332 0.588 ENST00000257832.2
ENST00000429939.2
ELF5

E74-like factor 5 (ets domain transcription factor)

chr20_+_306177 0.585 ENST00000544632.1
SOX12
SRY (sex determining region Y)-box 12
chr8_-_8318847 0.581 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr5_-_146435501 0.580 ENST00000336640.6
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr22_-_31688381 0.578 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr15_-_70387120 0.575 ENST00000539550.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr12_-_772901 0.574 ENST00000305108.4
NINJ2
ninjurin 2
chr3_-_48956818 0.569 ENST00000408959.2
ARIH2OS
ariadne homolog 2 opposite strand
chr12_-_71031185 0.569 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB


protein tyrosine phosphatase, receptor type, B


chr5_-_146435572 0.567 ENST00000394414.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr1_+_174933899 0.550 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr8_-_124553437 0.540 ENST00000517956.1
ENST00000443022.2
FBXO32

F-box protein 32

chr2_-_214016314 0.537 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr9_+_75229616 0.535 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr2_-_71454185 0.526 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr8_-_40755333 0.522 ENST00000297737.6
ENST00000315769.7
ZMAT4

zinc finger, matrin-type 4

chr4_-_116034979 0.514 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr20_-_43150601 0.513 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
SERINC3


serine incorporator 3


chr4_-_164534657 0.507 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr17_-_46035187 0.506 ENST00000300557.2
PRR15L
proline rich 15-like
chr3_+_178866199 0.506 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr9_+_135457530 0.503 ENST00000263610.2
BARHL1
BarH-like homeobox 1
chr12_+_6881678 0.489 ENST00000441671.2
ENST00000203629.2
LAG3

lymphocyte-activation gene 3

chr11_+_63606373 0.487 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2




MAP/microtubule affinity-regulating kinase 2




chr20_-_1309809 0.486 ENST00000360779.3
SDCBP2
syndecan binding protein (syntenin) 2
chr18_+_60382672 0.483 ENST00000400316.4
ENST00000262719.5
PHLPP1

PH domain and leucine rich repeat protein phosphatase 1

chr9_-_136933615 0.478 ENST00000371834.2
BRD3
bromodomain containing 3
chr4_+_86525299 0.474 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr2_+_175260451 0.474 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
SCRN3



secernin 3



chr2_-_160472952 0.470 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B



bromodomain adjacent to zinc finger domain, 2B



chr8_-_71316021 0.466 ENST00000452400.2
NCOA2
nuclear receptor coactivator 2
chr11_+_63606477 0.466 ENST00000508192.1
ENST00000361128.5
MARK2

MAP/microtubule affinity-regulating kinase 2

chr1_+_20512568 0.465 ENST00000375099.3
UBXN10
UBX domain protein 10
chr12_-_71031220 0.462 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr9_+_134165063 0.461 ENST00000372264.3
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr7_-_81399355 0.457 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_-_28503693 0.456 ENST00000373857.3
PTAFR
platelet-activating factor receptor
chr1_-_168106536 0.452 ENST00000537209.1
ENST00000361697.2
ENST00000546300.1
ENST00000367835.1
GPR161



G protein-coupled receptor 161



chr10_-_103578162 0.448 ENST00000361464.3
ENST00000357797.5
ENST00000370094.3
MGEA5


meningioma expressed antigen 5 (hyaluronidase)


chr21_-_19775973 0.442 ENST00000284885.3
TMPRSS15
transmembrane protease, serine 15
chr9_+_78505554 0.441 ENST00000545128.1
PCSK5
proprotein convertase subtilisin/kexin type 5
chr16_-_30122717 0.441 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr7_-_81399411 0.440 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_121944491 0.439 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1


FEZ family zinc finger 1


chr2_+_158114051 0.439 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr1_-_115259337 0.437 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr10_+_30722866 0.435 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr5_-_159846399 0.433 ENST00000297151.4
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr7_+_143701022 0.432 ENST00000408922.2
OR6B1
olfactory receptor, family 6, subfamily B, member 1
chr12_+_50135327 0.431 ENST00000549966.1
ENST00000547832.1
ENST00000547187.1
ENST00000548894.1
ENST00000546914.1
ENST00000552699.1
ENST00000267115.5
TMBIM6






transmembrane BAX inhibitor motif containing 6






chr8_+_52730143 0.430 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr12_+_131438443 0.424 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr1_+_110527308 0.424 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr4_-_111119804 0.424 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr18_+_56530136 0.418 ENST00000591083.1
ZNF532
zinc finger protein 532
chr5_-_64920115 0.417 ENST00000381018.3
ENST00000274327.7
TRIM23

tripartite motif containing 23

chr2_-_175260368 0.416 ENST00000342016.3
ENST00000362053.5
CIR1

corepressor interacting with RBPJ, 1

chr17_-_36358166 0.414 ENST00000537432.1
TBC1D3
TBC1 domain family, member 3
chr10_+_95848824 0.413 ENST00000371385.3
ENST00000371375.1
PLCE1

phospholipase C, epsilon 1

chr17_+_65374075 0.413 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr6_-_33168391 0.411 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB


retinoid X receptor, beta


chr11_+_63606558 0.411 ENST00000350490.7
ENST00000502399.3
MARK2

MAP/microtubule affinity-regulating kinase 2

chrX_-_19688475 0.406 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr1_+_161136180 0.405 ENST00000352210.5
ENST00000367999.4
ENST00000544598.1
ENST00000535223.1
ENST00000432542.2
PPOX




protoporphyrinogen oxidase




chr1_-_152131703 0.404 ENST00000316073.3
RPTN
repetin
chr22_-_38902300 0.404 ENST00000403230.1
DDX17
DEAD (Asp-Glu-Ala-Asp) box helicase 17
chr6_+_125540951 0.403 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr2_+_70142189 0.402 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr20_+_62795827 0.400 ENST00000328439.1
ENST00000536311.1
MYT1

myelin transcription factor 1

chr12_+_50135351 0.396 ENST00000549445.1
ENST00000550951.1
ENST00000549385.1
ENST00000548713.1
ENST00000548201.1
TMBIM6




transmembrane BAX inhibitor motif containing 6




chr14_-_21493649 0.392 ENST00000553442.1
ENST00000555869.1
ENST00000556457.1
ENST00000397844.2
ENST00000554415.1
NDRG2




NDRG family member 2




chr2_+_175260514 0.392 ENST00000424069.1
ENST00000427038.1
SCRN3

secernin 3

chr19_-_38743878 0.390 ENST00000587515.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr4_-_143227088 0.388 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr10_-_90751038 0.385 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2


actin, alpha 2, smooth muscle, aorta


chr1_-_152297679 0.381 ENST00000368799.1
FLG
filaggrin
chr11_-_72504681 0.381 ENST00000538536.1
ENST00000543304.1
ENST00000540587.1
ENST00000334805.6
STARD10



StAR-related lipid transfer (START) domain containing 10



chr8_-_28243934 0.378 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395


zinc finger protein 395


chr14_-_73493784 0.376 ENST00000553891.1
ZFYVE1
zinc finger, FYVE domain containing 1
chr6_-_159466136 0.376 ENST00000367066.3
ENST00000326965.6
TAGAP

T-cell activation RhoGTPase activating protein

chr4_-_123377880 0.374 ENST00000226730.4
IL2
interleukin 2
chr1_+_152956549 0.373 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr12_+_93096619 0.370 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr17_+_72427477 0.369 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr2_-_177502659 0.368 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr6_-_30043539 0.367 ENST00000376751.3
ENST00000244360.6
RNF39

ring finger protein 39

chr6_+_108977520 0.363 ENST00000540898.1
FOXO3
forkhead box O3
chr5_-_131132614 0.362 ENST00000307968.7
ENST00000307954.8
FNIP1

folliculin interacting protein 1

chr8_-_134309823 0.362 ENST00000414097.2
NDRG1
N-myc downstream regulated 1
chr6_-_117150198 0.362 ENST00000310357.3
ENST00000368549.3
ENST00000530250.1
GPRC6A


G protein-coupled receptor, family C, group 6, member A


chr12_+_93096759 0.361 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr11_+_71249071 0.359 ENST00000398534.3
KRTAP5-8
keratin associated protein 5-8
chr4_-_186696425 0.358 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2


sorbin and SH3 domain containing 2



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.5 1.4 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.4 5.4 GO:0033227 dsRNA transport(GO:0033227)
0.4 1.4 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.3 1.0 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.3 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 2.0 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 0.7 GO:0097325 melanocyte proliferation(GO:0097325)
0.3 1.9 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.3 1.6 GO:0030070 insulin processing(GO:0030070)
0.3 1.3 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 1.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 1.2 GO:0010157 response to chlorate(GO:0010157)
0.3 1.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 0.9 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.3 1.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 0.8 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 1.7 GO:0097338 response to clozapine(GO:0097338)
0.2 1.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 0.6 GO:0072186 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.2 0.6 GO:0090294 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 1.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2 0.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.2 3.4 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.2 0.7 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.2 1.0 GO:0006196 AMP catabolic process(GO:0006196)
0.2 0.5 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 1.7 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 2.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 0.8 GO:0032455 nerve growth factor processing(GO:0032455)
0.2 1.6 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.2 0.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 0.5 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1 0.4 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.8 GO:0060005 vestibular reflex(GO:0060005)
0.1 1.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.1 GO:0044254 multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.1 0.7 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.1 1.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.6 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.1 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 1.7 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.4 GO:1902869 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) regulation of amacrine cell differentiation(GO:1902869)
0.1 0.5 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 1.7 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.7 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.8 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.3 GO:2000910 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.1 2.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.5 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.1 0.6 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 2.4 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 1.0 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.5 GO:0009597 detection of virus(GO:0009597)
0.1 0.8 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.9 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.2 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.3 GO:0015917 aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.2 GO:2000974 inhibition of neuroepithelial cell differentiation(GO:0002085) trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.3 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 1.7 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 0.7 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 1.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 1.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.5 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.1 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.2 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.1 GO:0010159 specification of organ position(GO:0010159)
0.1 0.3 GO:0035864 response to potassium ion(GO:0035864)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 2.9 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.1 0.8 GO:0035878 nail development(GO:0035878)
0.1 0.4 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 0.5 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.3 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 1.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.3 GO:0014028 notochord formation(GO:0014028)
0.1 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0021590 cerebellum maturation(GO:0021590) cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.8 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.3 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 1.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.5 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.3 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:1903961 positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961)
0.0 0.4 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.3 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.1 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.0 1.1 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159) endothelial cell-cell adhesion(GO:0071603)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.7 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 2.7 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 1.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.7 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.5 GO:0033561 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.0 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 1.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.2 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.7 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 1.4 GO:0051646 mitochondrion localization(GO:0051646)
0.0 0.1 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 2.3 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.6 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416)
0.0 0.6 GO:0002076 osteoblast development(GO:0002076)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.4 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172) netrin-activated signaling pathway(GO:0038007)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.5 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 1.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.0 GO:0060353 regulation of cell adhesion molecule production(GO:0060353) positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.2 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0070649 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.1 GO:0043970 histone H3-K9 acetylation(GO:0043970)
0.0 0.1 GO:2000543 primitive streak formation(GO:0090009) positive regulation of gastrulation(GO:2000543)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.0 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) cellular response to cold(GO:0070417)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.6 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.0 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.0 0.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.3 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.2 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 0.9 GO:0035838 growing cell tip(GO:0035838)
0.2 3.0 GO:0097512 cardiac myofibril(GO:0097512)
0.2 2.4 GO:0031209 SCAR complex(GO:0031209)
0.2 1.2 GO:0044294 dendritic growth cone(GO:0044294)
0.1 1.2 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:1990923 PET complex(GO:1990923)
0.1 1.4 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.5 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.3 GO:0019034 viral replication complex(GO:0019034)
0.1 1.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.1 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 2.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.7 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.2 GO:0030658 transport vesicle membrane(GO:0030658)
0.1 1.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 2.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 1.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 1.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0043219 lateral loop(GO:0043219)
0.0 2.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.1 GO:0061700 Seh1-associated complex(GO:0035859) GATOR2 complex(GO:0061700)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 7.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.1 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 2.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 4.5 GO:0010008 endosome membrane(GO:0010008)
0.0 0.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 1.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.8 2.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 1.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 1.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.3 0.8 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.2 2.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 0.9 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.2 0.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 1.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.9 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.6 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 1.2 GO:0005119 smoothened binding(GO:0005119)
0.2 1.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.6 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 1.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.2 1.6 GO:0043426 MRF binding(GO:0043426)
0.2 1.6 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.5 GO:0090079 translation repressor activity, nucleic acid binding(GO:0000900) translation repressor activity(GO:0030371) translation regulator activity(GO:0045182) translation regulator activity, nucleic acid binding(GO:0090079)
0.1 1.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 1.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.5 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.5 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 1.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.5 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.3 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 1.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.3 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 0.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 2.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.0 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 2.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.4 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 6.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 1.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 1.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 3.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.7 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0016160 amylase activity(GO:0016160)
0.0 2.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 1.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0008607 AMP-activated protein kinase activity(GO:0004679) phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.3 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 2.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.8 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.0 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.3 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.0 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.4 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 5.3 PID_INSULIN_PATHWAY Insulin Pathway
0.1 1.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.2 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.9 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.7 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.8 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 2.2 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.2 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.9 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 3.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.5 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 1.4 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.3 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.5 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID_IGF1_PATHWAY IGF1 pathway
0.0 0.5 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 2.4 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 1.1 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 1.1 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.3 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 3.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.4 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.6 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.2 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.1 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.9 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 3.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 3.4 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.2 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.6 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.3 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.0 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 2.3 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.6 REACTOME_PI3K_AKT_ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.4 REACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.5 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 1.3 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 2.0 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME_IL_2_SIGNALING Genes involved in Interleukin-2 signaling
0.0 1.1 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.7 REACTOME_LIPOPROTEIN_METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.1 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.6 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.5 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL