Motif ID: FOSL1

Z-value: 2.217


Transcription factors associated with FOSL1:

Gene SymbolEntrez IDGene Name
FOSL1 ENSG00000175592.4 FOSL1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOSL1hg19_v2_chr11_-_65667884_656678950.872.5e-08Click!


Activity profile for motif FOSL1.

activity profile for motif FOSL1


Sorted Z-values histogram for motif FOSL1

Sorted Z-values for motif FOSL1



Network of associatons between targets according to the STRING database.



First level regulatory network of FOSL1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_36019123 17.587 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN


suprabasin


chr1_+_150480551 14.037 ENST00000369049.4
ENST00000369047.4
ECM1

extracellular matrix protein 1

chr1_+_150480576 13.869 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr18_+_21452964 13.046 ENST00000587184.1
LAMA3
laminin, alpha 3
chr18_+_21452804 11.145 ENST00000269217.6
LAMA3
laminin, alpha 3
chr6_+_47666275 11.024 ENST00000327753.3
ENST00000283303.2
GPR115

G protein-coupled receptor 115

chr17_-_39769005 10.788 ENST00000301653.4
ENST00000593067.1
KRT16

keratin 16

chr1_-_153029980 10.720 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr12_+_13349650 10.575 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1



epithelial membrane protein 1



chr1_+_183155373 10.495 ENST00000493293.1
ENST00000264144.4
LAMC2

laminin, gamma 2

chr1_-_153013588 10.470 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr1_+_152956549 9.937 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr19_+_35645817 9.806 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr19_+_35645618 9.728 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5






FXYD domain containing ion transport regulator 5






chr1_+_152881014 9.433 ENST00000368764.3
ENST00000392667.2
IVL

involucrin

chr1_-_153066998 9.394 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr13_+_78109884 8.614 ENST00000377246.3
ENST00000349847.3
SCEL

sciellin

chr5_+_135394840 8.514 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr2_+_113875466 8.275 ENST00000361779.3
ENST00000259206.5
ENST00000354115.2
IL1RN


interleukin 1 receptor antagonist


chr13_+_78109804 8.268 ENST00000535157.1
SCEL
sciellin
chr1_-_153521597 8.245 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr11_-_65667997 7.989 ENST00000312562.2
ENST00000534222.1
FOSL1

FOS-like antigen 1

chr7_+_48128194 7.544 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1


uridine phosphorylase 1


chr7_+_48128316 7.515 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr10_+_17270214 7.259 ENST00000544301.1
VIM
vimentin
chr9_+_35673853 6.887 ENST00000378357.4
CA9
carbonic anhydrase IX
chr11_-_65667884 6.840 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr17_+_74381343 6.647 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr1_-_153521714 6.579 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr1_-_205419053 6.468 ENST00000367154.1
LEMD1
LEM domain containing 1
chr11_-_62323702 6.380 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr16_+_50300427 5.612 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
ADCY7


adenylate cyclase 7


chr11_-_6341724 5.544 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr11_+_35198243 5.262 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr20_+_33759854 5.257 ENST00000216968.4
PROCR
protein C receptor, endothelial
chr6_+_74405804 5.195 ENST00000287097.5
CD109
CD109 molecule
chr6_+_74405501 5.157 ENST00000437994.2
ENST00000422508.2
CD109

CD109 molecule

chr4_-_39033963 4.917 ENST00000381938.3
TMEM156
transmembrane protein 156
chr11_-_66104237 4.809 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr3_-_48632593 4.796 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr19_-_51538118 4.757 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr12_-_48152853 4.689 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr12_-_95009837 4.688 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr17_+_4853442 4.636 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr19_-_51538148 4.632 ENST00000319590.4
ENST00000250351.4
KLK12

kallikrein-related peptidase 12

chr1_-_28520384 4.557 ENST00000305392.3
PTAFR
platelet-activating factor receptor
chr1_-_28520447 4.528 ENST00000539896.1
PTAFR
platelet-activating factor receptor
chr12_-_54813229 4.512 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr7_-_107643674 4.505 ENST00000222399.6
LAMB1
laminin, beta 1
chr11_-_6341844 4.505 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr19_-_35992780 4.496 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN


dermokine


chr12_-_48152611 4.457 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr18_+_61442629 4.411 ENST00000398019.2
ENST00000540675.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr11_-_102668879 4.379 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr19_-_51523412 4.118 ENST00000391805.1
ENST00000599077.1
KLK10

kallikrein-related peptidase 10

chr19_-_44285401 4.118 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_-_154943212 4.116 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr19_-_36004543 4.090 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN


dermokine


chr6_+_106546808 4.089 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr11_-_66103932 4.018 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr12_-_122238464 3.953 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr1_-_154943002 3.882 ENST00000606391.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr1_-_204121013 3.826 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr4_-_39034542 3.822 ENST00000344606.6
TMEM156
transmembrane protein 156
chr1_+_153003671 3.815 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr10_-_90611566 3.751 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr1_-_162381907 3.725 ENST00000367929.2
ENST00000359567.3
SH2D1B

SH2 domain containing 1B

chr1_-_204121102 3.665 ENST00000367202.4
ETNK2
ethanolamine kinase 2
chr1_-_95007193 3.658 ENST00000370207.4
ENST00000334047.7
F3

coagulation factor III (thromboplastin, tissue factor)

chr9_+_140119618 3.640 ENST00000359069.2
C9orf169
chromosome 9 open reading frame 169
chr11_+_12308447 3.635 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr12_-_95510743 3.635 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr1_-_204121298 3.581 ENST00000367199.2
ETNK2
ethanolamine kinase 2
chr16_-_28518153 3.577 ENST00000356897.1
IL27
interleukin 27
chr11_+_394196 3.551 ENST00000331563.2
ENST00000531857.1
PKP3

plakophilin 3

chr11_-_66103867 3.485 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr19_-_51523275 3.326 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr1_-_150208320 3.246 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr17_-_39780819 3.190 ENST00000311208.8
KRT17
keratin 17
chr1_+_24645865 3.160 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr11_+_35198118 3.129 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
CD44



CD44 molecule (Indian blood group)



chr1_+_24645807 3.110 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_24646002 3.087 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr11_-_102826434 3.002 ENST00000340273.4
ENST00000260302.3
MMP13

matrix metallopeptidase 13 (collagenase 3)

chr2_+_220492373 2.987 ENST00000317151.3
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr5_+_149877334 2.971 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr17_-_33390667 2.888 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL


ring finger and FYVE-like domain containing E3 ubiquitin protein ligase


chr2_-_65593784 2.841 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chrX_+_99899180 2.795 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr4_+_84457250 2.781 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr16_-_30125177 2.778 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr1_-_151965048 2.736 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr11_-_2924720 2.709 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr9_+_4985016 2.694 ENST00000539801.1
JAK2
Janus kinase 2
chr11_-_2924970 2.689 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr2_+_191792376 2.677 ENST00000409428.1
ENST00000409215.1
GLS

glutaminase

chr17_-_9694614 2.652 ENST00000330255.5
ENST00000571134.1
DHRS7C

dehydrogenase/reductase (SDR family) member 7C

chr18_+_61554932 2.648 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2


serpin peptidase inhibitor, clade B (ovalbumin), member 2


chr3_+_57094469 2.637 ENST00000334325.1
SPATA12
spermatogenesis associated 12
chr14_+_103801140 2.607 ENST00000561325.1
ENST00000392715.2
ENST00000559130.1
ENST00000559532.1
ENST00000558506.1
EIF5




eukaryotic translation initiation factor 5




chr17_-_18908040 2.589 ENST00000388995.6
FAM83G
family with sequence similarity 83, member G
chr7_+_55177416 2.576 ENST00000450046.1
ENST00000454757.2
EGFR

epidermal growth factor receptor

chr6_+_41604747 2.572 ENST00000419164.1
ENST00000373051.2
MDFI

MyoD family inhibitor

chr8_-_42623747 2.555 ENST00000534622.1
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr4_+_84457529 2.527 ENST00000264409.4
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr16_+_58533951 2.476 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4










NDRG family member 4










chr3_-_151034734 2.430 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr2_+_33359687 2.428 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1


latent transforming growth factor beta binding protein 1


chr15_-_70388599 2.406 ENST00000560996.1
ENST00000558201.1
TLE3

transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)

chr2_-_85641162 2.401 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
CAPG


capping protein (actin filament), gelsolin-like


chr15_-_70388943 2.386 ENST00000559048.1
ENST00000560939.1
ENST00000440567.3
ENST00000557907.1
ENST00000558379.1
ENST00000451782.2
ENST00000559929.1
TLE3






transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)






chr12_-_53625958 2.385 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG



retinoic acid receptor, gamma



chr4_-_987217 2.376 ENST00000361661.2
ENST00000398516.2
SLC26A1

solute carrier family 26 (anion exchanger), member 1

chr17_-_45928521 2.363 ENST00000536300.1
SP6
Sp6 transcription factor
chr8_-_42623924 2.354 ENST00000276410.2
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr1_-_150208291 2.343 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr3_-_98241358 2.338 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1



claudin domain containing 1



chr6_+_106534192 2.326 ENST00000369091.2
ENST00000369096.4
PRDM1

PR domain containing 1, with ZNF domain

chr14_+_96722152 2.315 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr11_-_82708519 2.290 ENST00000534301.1
RAB30
RAB30, member RAS oncogene family
chr9_-_35112376 2.286 ENST00000488109.2
FAM214B
family with sequence similarity 214, member B
chr2_+_33359646 2.278 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr14_+_96722539 2.272 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr19_+_39279838 2.268 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr10_+_49892904 2.254 ENST00000360890.2
WDFY4
WDFY family member 4
chr1_-_150208363 2.252 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr5_-_140013275 2.237 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14


CD14 molecule


chr1_+_26605618 2.227 ENST00000270792.5
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr2_+_28615669 2.186 ENST00000379619.1
ENST00000264716.4
FOSL2

FOS-like antigen 2

chr9_+_124329336 2.185 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP


DAB2 interacting protein


chr1_+_155006300 2.172 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1



DC-STAMP domain containing 1



chr11_+_706219 2.159 ENST00000533500.1
EPS8L2
EPS8-like 2
chr13_+_32838801 2.157 ENST00000542859.1
FRY
furry homolog (Drosophila)
chr17_-_39743139 2.139 ENST00000167586.6
KRT14
keratin 14
chr9_+_4985228 2.124 ENST00000381652.3
JAK2
Janus kinase 2
chr17_+_73717407 2.097 ENST00000579662.1
ITGB4
integrin, beta 4
chr8_+_126442563 2.080 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr9_-_130341268 2.063 ENST00000373314.3
FAM129B
family with sequence similarity 129, member B
chr9_-_35111570 2.055 ENST00000378561.1
ENST00000603301.1
FAM214B

family with sequence similarity 214, member B

chr15_+_44829334 2.037 ENST00000535391.1
EIF3J
eukaryotic translation initiation factor 3, subunit J
chr6_+_32121218 2.009 ENST00000414204.1
ENST00000361568.2
ENST00000395523.1
PPT2


palmitoyl-protein thioesterase 2


chr3_-_37216055 2.002 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr10_-_76868931 1.995 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13




dual specificity phosphatase 13




chr7_+_128095945 1.968 ENST00000257696.4
HILPDA
hypoxia inducible lipid droplet-associated
chr19_-_6670128 1.936 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr3_-_149095652 1.928 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr9_-_35111420 1.865 ENST00000378557.1
FAM214B
family with sequence similarity 214, member B
chr17_-_43502987 1.838 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr1_+_26606608 1.821 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr17_+_73717551 1.820 ENST00000450894.3
ITGB4
integrin, beta 4
chr8_-_125384927 1.816 ENST00000297632.6
TMEM65
transmembrane protein 65
chr11_+_57308979 1.794 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr15_+_40531243 1.778 ENST00000558055.1
ENST00000455577.2
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr11_+_706113 1.756 ENST00000318562.8
ENST00000533256.1
ENST00000534755.1
EPS8L2


EPS8-like 2


chr7_+_128095900 1.753 ENST00000435296.2
HILPDA
hypoxia inducible lipid droplet-associated
chr15_-_70994612 1.739 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA


uveal autoantigen with coiled-coil domains and ankyrin repeats


chr18_+_61143994 1.738 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr7_+_134528635 1.730 ENST00000445569.2
CALD1
caldesmon 1
chr13_-_103719196 1.703 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr18_+_52495426 1.702 ENST00000262094.5
RAB27B
RAB27B, member RAS oncogene family
chr17_-_27045405 1.679 ENST00000430132.2
RAB34
RAB34, member RAS oncogene family
chr5_+_145317356 1.667 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr16_+_83986827 1.647 ENST00000393306.1
ENST00000565123.1
OSGIN1

oxidative stress induced growth inhibitor 1

chr1_+_156095951 1.610 ENST00000448611.2
ENST00000368297.1
LMNA

lamin A/C

chr4_-_80329356 1.605 ENST00000358842.3
GK2
glycerol kinase 2
chr15_-_56209306 1.598 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4


neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase


chr19_+_17865011 1.598 ENST00000596462.1
ENST00000596865.1
ENST00000598960.1
ENST00000539407.1
FCHO1



FCH domain only 1



chr11_-_111783919 1.596 ENST00000531198.1
ENST00000533879.1
CRYAB

crystallin, alpha B

chr6_-_35888824 1.561 ENST00000361690.3
ENST00000512445.1
SRPK1

SRSF protein kinase 1

chr1_-_155947951 1.559 ENST00000313695.7
ENST00000497907.1
ARHGEF2

Rho/Rac guanine nucleotide exchange factor (GEF) 2

chr2_-_165697920 1.547 ENST00000342193.4
ENST00000375458.2
COBLL1

cordon-bleu WH2 repeat protein-like 1

chr7_-_42276612 1.542 ENST00000395925.3
ENST00000437480.1
GLI3

GLI family zinc finger 3

chr16_-_2908155 1.536 ENST00000571228.1
ENST00000161006.3
PRSS22

protease, serine, 22

chr14_+_94492674 1.528 ENST00000203664.5
ENST00000553723.1
OTUB2

OTU domain, ubiquitin aldehyde binding 2

chr6_-_35888905 1.487 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1


SRSF protein kinase 1


chr12_+_7023735 1.486 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2


enolase 2 (gamma, neuronal)


chr15_+_89182178 1.483 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_-_27503770 1.466 ENST00000533112.1
MYO18A
myosin XVIIIA
chr10_+_30722866 1.462 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr16_+_81678957 1.457 ENST00000398040.4
CMIP
c-Maf inducing protein
chr6_-_84140757 1.427 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1


malic enzyme 1, NADP(+)-dependent, cytosolic


chr2_+_202316392 1.425 ENST00000194530.3
ENST00000392249.2
STRADB

STE20-related kinase adaptor beta

chr2_+_87808725 1.423 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr10_-_93392811 1.412 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr14_-_75643296 1.409 ENST00000303575.4
TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr12_-_57914275 1.404 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DDIT3




DNA-damage-inducible transcript 3




chr1_-_150208412 1.401 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E



acidic (leucine-rich) nuclear phosphoprotein 32 family, member E



chr15_+_40531621 1.390 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr17_-_27045427 1.387 ENST00000301043.6
ENST00000412625.1
RAB34

RAB34, member RAS oncogene family

chr6_+_106959718 1.381 ENST00000369066.3
AIM1
absent in melanoma 1
chr9_-_127177703 1.378 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
PSMB7


proteasome (prosome, macropain) subunit, beta type, 7


chr11_+_128563948 1.370 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr3_-_81792780 1.367 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr1_-_27816641 1.361 ENST00000430629.2
WASF2
WAS protein family, member 2
chr11_+_128563652 1.342 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr4_+_74606223 1.333 ENST00000307407.3
ENST00000401931.1
IL8

interleukin 8

chr12_+_7023491 1.331 ENST00000541477.1
ENST00000229277.1
ENO2

enolase 2 (gamma, neuronal)

chr12_-_10324716 1.331 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1



oxidized low density lipoprotein (lectin-like) receptor 1



chr11_-_47207390 1.323 ENST00000539589.1
ENST00000528462.1
PACSIN3

protein kinase C and casein kinase substrate in neurons 3

chr12_+_9142131 1.302 ENST00000356986.3
ENST00000266551.4
KLRG1

killer cell lectin-like receptor subfamily G, member 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.5 19.5 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
3.8 15.1 GO:0006218 uridine catabolic process(GO:0006218)
3.1 9.4 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
3.0 9.1 GO:1904298 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
2.5 14.8 GO:0007296 vitellogenesis(GO:0007296)
2.3 9.1 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
2.2 6.6 GO:0046521 sphingoid catabolic process(GO:0046521)
1.7 10.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
1.5 12.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
1.5 42.9 GO:0031581 hemidesmosome assembly(GO:0031581)
1.4 8.6 GO:1903575 cornified envelope assembly(GO:1903575)
1.3 6.4 GO:0033078 extrathymic T cell differentiation(GO:0033078)
1.2 3.7 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.1 5.7 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
1.1 4.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.1 4.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
1.1 27.9 GO:0030502 negative regulation of bone mineralization(GO:0030502)
1.0 8.4 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.9 3.7 GO:0035425 autocrine signaling(GO:0035425)
0.9 4.4 GO:0002159 desmosome assembly(GO:0002159)
0.7 6.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.7 2.1 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.7 2.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.6 7.8 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.6 2.6 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.6 11.5 GO:0051546 keratinocyte migration(GO:0051546)
0.6 1.9 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.6 42.5 GO:0018149 peptide cross-linking(GO:0018149)
0.6 2.4 GO:0070384 Harderian gland development(GO:0070384)
0.6 2.9 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.6 2.2 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.5 2.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 2.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.5 1.6 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.5 9.4 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.5 2.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.5 1.5 GO:1903028 positive regulation of opsonization(GO:1903028)
0.5 4.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.4 2.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.4 1.7 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.4 1.2 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.4 11.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4 6.1 GO:0044351 macropinocytosis(GO:0044351) phagosome-lysosome fusion(GO:0090385)
0.4 10.6 GO:0032060 bleb assembly(GO:0032060)
0.4 1.6 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.4 1.9 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.4 1.5 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798) mammary gland specification(GO:0060594)
0.4 1.4 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.3 2.8 GO:0001866 NK T cell proliferation(GO:0001866)
0.3 4.0 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.3 4.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.3 1.0 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.3 1.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.3 2.5 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3 3.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 0.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.3 0.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 1.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792) regulation of determination of dorsal identity(GO:2000015)
0.3 4.7 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.3 2.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.3 1.3 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.3 3.6 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.3 5.6 GO:0071361 cellular response to ethanol(GO:0071361)
0.3 2.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.3 1.0 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.3 0.8 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.2 1.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 1.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.2 3.8 GO:0045109 intermediate filament organization(GO:0045109)
0.2 1.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 0.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 4.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 3.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.2 0.7 GO:0010949 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.2 10.1 GO:0043486 histone exchange(GO:0043486)
0.2 1.4 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.2 2.0 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.2 8.7 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.2 9.2 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 1.2 GO:0030421 defecation(GO:0030421)
0.2 0.4 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 2.5 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.2 2.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 2.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.6 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 3.9 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.8 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 2.9 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 0.4 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.4 GO:0090024 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 1.7 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.5 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.8 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 2.2 GO:0001765 membrane raft assembly(GO:0001765)
0.1 2.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 5.0 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 6.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 7.7 GO:0033574 response to testosterone(GO:0033574)
0.1 1.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.7 GO:0038124 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.1 4.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.1 0.8 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1 3.4 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 2.4 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 1.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 7.9 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 0.4 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 1.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.3 GO:1901656 glycoside transport(GO:1901656)
0.1 9.1 GO:0070268 cornification(GO:0070268)
0.1 4.8 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.1 1.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 2.0 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717)
0.1 2.1 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 1.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 10.3 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 8.2 GO:0002062 chondrocyte differentiation(GO:0002062)
0.1 3.3 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 5.2 GO:0030834 regulation of actin filament depolymerization(GO:0030834)
0.1 0.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.1 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.1 0.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 3.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.5 GO:0035973 aggrephagy(GO:0035973)
0.1 0.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.9 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.4 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.8 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.8 GO:1903541 regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.0 0.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.6 GO:0050954 sensory perception of sound(GO:0007605) sensory perception of mechanical stimulus(GO:0050954)
0.0 3.2 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.0 GO:0051412 response to corticosterone(GO:0051412)
0.0 1.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.5 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 1.3 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 1.5 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.0 1.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.5 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.2 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 1.2 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.8 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.8 GO:0015695 organic cation transport(GO:0015695)
0.0 1.4 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 1.0 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.9 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.3 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.0 0.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.6 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.3 GO:0006968 cellular defense response(GO:0006968)
0.0 1.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.7 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 1.3 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.1 GO:1990182 exosomal secretion(GO:1990182)
0.0 2.3 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 1.3 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 1.8 GO:0003231 cardiac ventricle development(GO:0003231)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.7 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 1.4 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.9 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007) negative regulation of synapse assembly(GO:0051964)
0.0 0.5 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.4 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.6 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0 1.3 GO:0051225 spindle assembly(GO:0051225)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.0 GO:0005607 laminin-2 complex(GO:0005607)
3.1 25.1 GO:0005610 laminin-5 complex(GO:0005610)
1.8 10.6 GO:0070435 Shc-EGFR complex(GO:0070435)
1.6 27.9 GO:0031089 platelet dense granule lumen(GO:0031089)
1.2 4.8 GO:0030934 anchoring collagen complex(GO:0030934)
1.2 8.4 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.2 75.8 GO:0001533 cornified envelope(GO:0001533)
1.1 4.5 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
1.1 7.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.7 2.2 GO:1990032 parallel fiber(GO:1990032)
0.5 10.1 GO:0000812 Swr1 complex(GO:0000812)
0.5 1.4 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.4 2.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 2.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.4 1.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.3 11.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 2.5 GO:0005638 lamin filament(GO:0005638)
0.3 0.8 GO:0033565 ESCRT-0 complex(GO:0033565)
0.2 4.0 GO:0097512 cardiac myofibril(GO:0097512)
0.2 6.4 GO:0031528 microvillus membrane(GO:0031528)
0.2 5.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 4.1 GO:0030056 hemidesmosome(GO:0030056)
0.2 4.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 4.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.2 0.8 GO:1990812 growth cone filopodium(GO:1990812)
0.2 3.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 7.5 GO:0043034 costamere(GO:0043034)
0.2 25.4 GO:0005882 intermediate filament(GO:0005882)
0.2 1.1 GO:0032437 cuticular plate(GO:0032437)
0.2 4.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 2.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.8 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.7 GO:0030478 actin cap(GO:0030478)
0.1 9.7 GO:0005902 microvillus(GO:0005902)
0.1 0.9 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 13.6 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.7 GO:0097452 GAIT complex(GO:0097452)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 2.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 10.5 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 1.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 6.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 2.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 0.9 GO:0097433 dense body(GO:0097433)
0.1 7.9 GO:0005604 basement membrane(GO:0005604)
0.1 0.4 GO:0071817 MMXD complex(GO:0071817)
0.1 2.8 GO:0016592 mediator complex(GO:0016592)
0.1 0.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 1.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 3.1 GO:0031904 endosome lumen(GO:0031904)
0.1 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 2.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 12.5 GO:0030027 lamellipodium(GO:0030027)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 5.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 2.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.6 GO:0031430 M band(GO:0031430)
0.0 1.5 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0031010 ISWI-type complex(GO:0031010)
0.0 2.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 2.0 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.6 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 1.9 GO:0005811 lipid particle(GO:0005811)
0.0 2.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 5.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 4.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 1.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 2.2 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 2.2 GO:0000922 spindle pole(GO:0000922)
0.0 0.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 2.0 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.6 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 26.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
3.0 15.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
2.8 8.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
1.7 8.6 GO:0004992 platelet activating factor receptor activity(GO:0004992)
1.5 4.6 GO:0004947 bradykinin receptor activity(GO:0004947)
1.5 10.6 GO:0048408 epidermal growth factor binding(GO:0048408)
1.3 9.4 GO:1990254 keratin filament binding(GO:1990254)
1.3 19.3 GO:0030280 structural constituent of epidermis(GO:0030280)
1.1 6.6 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
1.1 11.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
1.1 7.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.9 2.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.9 4.7 GO:0050436 microfibril binding(GO:0050436)
0.9 2.7 GO:0008859 exoribonuclease II activity(GO:0008859)
0.8 4.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.8 9.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.7 3.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.6 3.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.6 3.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.5 2.7 GO:0004359 glutaminase activity(GO:0004359)
0.5 4.8 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.5 1.6 GO:0004370 glycerol kinase activity(GO:0004370)
0.5 6.7 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.5 1.4 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.4 2.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.4 1.3 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.3 1.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.3 3.6 GO:0038132 neuregulin binding(GO:0038132)
0.3 4.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.3 1.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.3 11.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.3 20.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 0.9 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.3 9.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 5.5 GO:0044548 S100 protein binding(GO:0044548)
0.3 1.0 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 4.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 2.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 1.4 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.2 1.2 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 6.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 5.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 2.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 4.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 2.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 0.4 GO:0031893 vasopressin receptor binding(GO:0031893)
0.2 12.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 13.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.2 0.7 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 1.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 6.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.0 GO:1903135 cupric ion binding(GO:1903135)
0.2 0.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 1.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 3.5 GO:0030275 LRR domain binding(GO:0030275)
0.1 4.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 4.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 4.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 1.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 2.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.7 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 2.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.9 GO:0048156 tau protein binding(GO:0048156)
0.1 2.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 1.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 1.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 7.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.5 GO:0031489 myosin V binding(GO:0031489)
0.1 1.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 9.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.8 GO:0019534 toxin transporter activity(GO:0019534)
0.1 3.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 8.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 19.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.9 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 59.2 GO:0005198 structural molecule activity(GO:0005198)
0.1 1.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.9 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 2.7 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.7 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 1.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.5 GO:0043531 ADP binding(GO:0043531)
0.0 5.0 GO:0008201 heparin binding(GO:0008201)
0.0 2.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 2.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.0 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 1.8 GO:0019838 growth factor binding(GO:0019838)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 1.4 GO:0002039 p53 binding(GO:0002039)
0.0 6.8 GO:0005525 GTP binding(GO:0005525)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 2.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 4.0 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.8 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 1.0 GO:0008083 growth factor activity(GO:0008083)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 45.2 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.5 30.7 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.4 4.8 ST_IL_13_PATHWAY Interleukin 13 (IL-13) Pathway
0.3 9.3 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.3 9.1 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.3 5.6 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.3 14.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.3 8.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 19.7 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.2 6.2 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.2 1.5 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 10.0 PID_IL1_PATHWAY IL1-mediated signaling events
0.2 3.6 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.1 3.6 PID_IL27_PATHWAY IL27-mediated signaling events
0.1 28.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.8 PID_PI3KCI_PATHWAY Class I PI3K signaling events
0.1 3.3 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 8.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 5.9 PID_AURORA_B_PATHWAY Aurora B signaling
0.1 4.0 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.4 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 4.3 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.1 5.3 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.1 1.6 PID_REELIN_PATHWAY Reelin signaling pathway
0.1 1.7 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 15.4 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 2.5 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 1.4 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.1 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.6 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.5 PID_HEDGEHOG_GLI_PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.8 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 4.8 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.6 PID_CXCR4_PATHWAY CXCR4-mediated signaling events
0.0 6.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 1.0 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.3 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 15.1 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.5 11.1 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.4 8.4 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 5.6 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.4 10.6 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.3 39.3 REACTOME_CELL_JUNCTION_ORGANIZATION Genes involved in Cell junction organization
0.3 4.9 REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.3 4.5 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 6.7 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.9 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.2 9.1 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.2 3.1 REACTOME_NFKB_IS_ACTIVATED_AND_SIGNALS_SURVIVAL Genes involved in NF-kB is activated and signals survival
0.2 9.9 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.2 2.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 4.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 6.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 8.4 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.3 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 3.1 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 1.5 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.7 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.1 9.1 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.1 3.7 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 2.7 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.7 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 2.9 REACTOME_SYNTHESIS_OF_PA Genes involved in Synthesis of PA
0.1 3.8 REACTOME_SIGNAL_TRANSDUCTION_BY_L1 Genes involved in Signal transduction by L1
0.1 0.8 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 3.0 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.1 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 4.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 1.1 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 1.2 REACTOME_TAK1_ACTIVATES_NFKB_BY_PHOSPHORYLATION_AND_ACTIVATION_OF_IKKS_COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 2.2 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 4.4 REACTOME_AMYLOIDS Genes involved in Amyloids
0.1 3.6 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.7 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.3 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.4 REACTOME_REGULATION_OF_AMPK_ACTIVITY_VIA_LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.8 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 4.0 REACTOME_L1CAM_INTERACTIONS Genes involved in L1CAM interactions
0.0 1.5 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.0 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 2.5 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.6 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.2 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION Genes involved in Extracellular matrix organization
0.0 4.9 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 0.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.2 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 4.9 REACTOME_G_ALPHA_I_SIGNALLING_EVENTS Genes involved in G alpha (i) signalling events
0.0 1.8 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.6 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.2 REACTOME_PPARA_ACTIVATES_GENE_EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.2 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.5 REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS Genes involved in Trafficking of AMPA receptors