Motif ID: ETV2

Z-value: 0.644


Transcription factors associated with ETV2:

Gene SymbolEntrez IDGene Name
ETV2 ENSG00000105672.10 ETV2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ETV2hg19_v2_chr19_+_36132631_361326950.106.5e-01Click!


Activity profile for motif ETV2.

activity profile for motif ETV2


Sorted Z-values histogram for motif ETV2

Sorted Z-values for motif ETV2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETV2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_64851496 1.546 ENST00000404147.3
ENST00000275517.3
CDCA5

cell division cycle associated 5

chr6_-_42946888 1.499 ENST00000244546.4
PEX6
peroxisomal biogenesis factor 6
chr6_-_42946947 1.470 ENST00000304611.8
PEX6
peroxisomal biogenesis factor 6
chr15_+_69706585 1.290 ENST00000559279.1
ENST00000395392.2
KIF23

kinesin family member 23

chr1_-_63988846 1.226 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP


integrin beta 3 binding protein (beta3-endonexin)


chr15_+_69706643 1.206 ENST00000352331.4
ENST00000260363.4
KIF23

kinesin family member 23

chrX_+_69509927 1.096 ENST00000374403.3
KIF4A
kinesin family member 4A
chr2_+_102953608 1.040 ENST00000311734.2
ENST00000409584.1
IL1RL1

interleukin 1 receptor-like 1

chr1_+_45212074 1.038 ENST00000372217.1
KIF2C
kinesin family member 2C
chr20_-_54967187 1.001 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA













aurora kinase A













chr1_+_45212051 0.997 ENST00000372222.3
KIF2C
kinesin family member 2C
chr2_+_113885138 0.986 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr7_+_100770328 0.930 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr1_-_43855444 0.887 ENST00000372455.4
MED8
mediator complex subunit 8
chr12_+_47473369 0.884 ENST00000546455.1
PCED1B
PC-esterase domain containing 1B
chr17_-_8113542 0.839 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
AURKB


aurora kinase B


chr1_+_169764163 0.788 ENST00000413811.2
ENST00000359326.4
ENST00000456684.1
C1orf112


chromosome 1 open reading frame 112


chr14_-_100842588 0.766 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
WARS











tryptophanyl-tRNA synthetase











chr22_+_19466980 0.756 ENST00000407835.1
ENST00000438587.1
CDC45

cell division cycle 45

chr13_-_60737898 0.752 ENST00000377908.2
ENST00000400319.1
ENST00000400320.1
ENST00000267215.4
DIAPH3



diaphanous-related formin 3



chr15_+_74833518 0.744 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr1_+_32687971 0.739 ENST00000373586.1
EIF3I
eukaryotic translation initiation factor 3, subunit I
chr13_-_60738003 0.709 ENST00000400330.1
ENST00000400324.4
DIAPH3

diaphanous-related formin 3

chr1_-_150208320 0.706 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr14_+_75348592 0.684 ENST00000334220.4
DLST
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr6_-_11382478 0.676 ENST00000397378.3
ENST00000513989.1
ENST00000508546.1
ENST00000504387.1
NEDD9



neural precursor cell expressed, developmentally down-regulated 9



chr12_-_123215306 0.668 ENST00000356987.2
ENST00000436083.2
HCAR1

hydroxycarboxylic acid receptor 1

chr12_+_6602517 0.644 ENST00000315579.5
ENST00000539714.1
NCAPD2

non-SMC condensin I complex, subunit D2

chr12_+_9102632 0.636 ENST00000539240.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr7_+_2281843 0.620 ENST00000356714.1
ENST00000397049.1
NUDT1

nudix (nucleoside diphosphate linked moiety X)-type motif 1

chr19_-_48753028 0.616 ENST00000522431.1
CARD8
caspase recruitment domain family, member 8
chr3_+_52321827 0.608 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
GLYCTK




glycerate kinase




chr17_-_45908875 0.606 ENST00000351111.2
ENST00000414011.1
MRPL10

mitochondrial ribosomal protein L10

chr3_-_50340996 0.602 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1





hyaluronoglucosaminidase 1





chr14_+_21387508 0.602 ENST00000555624.1
RP11-84C10.2
RP11-84C10.2
chr9_+_106856831 0.599 ENST00000303219.8
ENST00000374787.3
SMC2

structural maintenance of chromosomes 2

chr1_-_153066998 0.598 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr15_+_75639773 0.574 ENST00000567657.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chrX_+_79591003 0.573 ENST00000538312.1
FAM46D
family with sequence similarity 46, member D
chr16_-_85722530 0.568 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr12_-_47473425 0.564 ENST00000550413.1
AMIGO2
adhesion molecule with Ig-like domain 2
chr4_+_2814011 0.549 ENST00000502260.1
ENST00000435136.2
SH3BP2

SH3-domain binding protein 2

chr15_+_40886199 0.544 ENST00000346991.5
ENST00000528975.1
ENST00000527044.1
CASC5


cancer susceptibility candidate 5


chr2_+_234160217 0.536 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
ATG16L1




autophagy related 16-like 1 (S. cerevisiae)




chr1_-_153113927 0.536 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr3_-_49055991 0.536 ENST00000441576.2
ENST00000420952.2
ENST00000341949.4
ENST00000395462.4
DALRD3



DALR anticodon binding domain containing 3



chr21_-_46340807 0.535 ENST00000397846.3
ENST00000524251.1
ENST00000522688.1
ITGB2


integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)


chr7_+_44084262 0.530 ENST00000456905.1
ENST00000440166.1
ENST00000452943.1
ENST00000468694.1
ENST00000494774.1
ENST00000490734.2
DBNL





drebrin-like





chr19_+_10397648 0.528 ENST00000340992.4
ENST00000393717.2
ICAM4

intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)

chr3_-_28390120 0.528 ENST00000334100.6
AZI2
5-azacytidine induced 2
chr3_-_28390298 0.528 ENST00000457172.1
AZI2
5-azacytidine induced 2
chr19_-_19051103 0.523 ENST00000542541.2
ENST00000433218.2
HOMER3

homer homolog 3 (Drosophila)

chr6_+_28048753 0.523 ENST00000377325.1
ZNF165
zinc finger protein 165
chr12_-_47473642 0.519 ENST00000266581.4
AMIGO2
adhesion molecule with Ig-like domain 2
chr10_+_13203543 0.517 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
MCM10


minichromosome maintenance complex component 10


chr6_-_31869769 0.515 ENST00000375527.2
ZBTB12
zinc finger and BTB domain containing 12
chr7_+_2281882 0.511 ENST00000397046.1
ENST00000397048.1
ENST00000454650.1
NUDT1


nudix (nucleoside diphosphate linked moiety X)-type motif 1


chr19_-_48759119 0.510 ENST00000522889.1
ENST00000520753.1
ENST00000519940.1
ENST00000519332.1
ENST00000521437.1
ENST00000520007.1
ENST00000521613.1
CARD8






caspase recruitment domain family, member 8






chr8_-_122653630 0.508 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr12_-_47473557 0.508 ENST00000321382.3
AMIGO2
adhesion molecule with Ig-like domain 2
chr1_+_169337172 0.507 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
BLZF1



basic leucine zipper nuclear factor 1



chr12_+_1800179 0.503 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr4_+_2813946 0.499 ENST00000442312.2
SH3BP2
SH3-domain binding protein 2
chr5_+_157158205 0.496 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr3_-_28390415 0.495 ENST00000414162.1
ENST00000420543.2
AZI2

5-azacytidine induced 2

chr17_+_7482785 0.494 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68


CD68 molecule


chr19_-_48753064 0.494 ENST00000520153.1
ENST00000357778.5
ENST00000520015.1
CARD8


caspase recruitment domain family, member 8


chr19_-_15344243 0.492 ENST00000602233.1
EPHX3
epoxide hydrolase 3
chr7_-_99698338 0.490 ENST00000354230.3
ENST00000425308.1
MCM7

minichromosome maintenance complex component 7

chr13_+_46039037 0.489 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr10_-_75401500 0.486 ENST00000359322.4
MYOZ1
myozenin 1
chr6_+_57182400 0.484 ENST00000607273.1
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr17_+_33914276 0.482 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1



adaptor-related protein complex 2, beta 1 subunit



chr11_-_134093827 0.477 ENST00000534548.2
NCAPD3
non-SMC condensin II complex, subunit D3
chr12_+_51632666 0.476 ENST00000604900.1
DAZAP2
DAZ associated protein 2
chr19_+_16308659 0.469 ENST00000590263.1
ENST00000590756.1
ENST00000541844.1
AP1M1


adaptor-related protein complex 1, mu 1 subunit


chr7_-_56101826 0.468 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr19_+_10397621 0.465 ENST00000380770.3
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr7_+_44084233 0.459 ENST00000448521.1
DBNL
drebrin-like
chr12_+_21590549 0.459 ENST00000545178.1
ENST00000240651.9
PYROXD1

pyridine nucleotide-disulphide oxidoreductase domain 1

chrX_+_17755563 0.458 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1



sex comb on midleg-like 1 (Drosophila)



chr11_-_64084959 0.456 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
TRMT112



tRNA methyltransferase 11-2 homolog (S. cerevisiae)



chr1_-_28969517 0.453 ENST00000263974.4
ENST00000373824.4
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr2_-_238322800 0.452 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
COL6A3





collagen, type VI, alpha 3





chr5_+_147763498 0.451 ENST00000340253.5
FBXO38
F-box protein 38
chr2_-_238323007 0.447 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr2_-_45838374 0.444 ENST00000263736.4
SRBD1
S1 RNA binding domain 1
chr17_-_43510282 0.442 ENST00000290470.3
ARHGAP27
Rho GTPase activating protein 27
chr14_-_75593708 0.441 ENST00000557673.1
ENST00000238616.5
NEK9

NIMA-related kinase 9

chr18_-_59274139 0.439 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr19_+_16308711 0.438 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1


adaptor-related protein complex 1, mu 1 subunit


chr11_+_6226782 0.437 ENST00000316375.2
C11orf42
chromosome 11 open reading frame 42
chr1_+_84609944 0.437 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_150208291 0.435 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_150208363 0.429 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr2_-_238322770 0.429 ENST00000472056.1
COL6A3
collagen, type VI, alpha 3
chr2_+_234160340 0.428 ENST00000417017.1
ENST00000392020.4
ENST00000392018.1
ATG16L1


autophagy related 16-like 1 (S. cerevisiae)


chr8_+_38586068 0.427 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
TACC1


transforming, acidic coiled-coil containing protein 1


chr5_+_110074685 0.421 ENST00000355943.3
ENST00000447245.2
SLC25A46

solute carrier family 25, member 46

chr2_+_201981119 0.421 ENST00000395148.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr17_+_33914460 0.418 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr7_-_107643674 0.416 ENST00000222399.6
LAMB1
laminin, beta 1
chr14_+_93389425 0.415 ENST00000216492.5
ENST00000334654.4
CHGA

chromogranin A (parathyroid secretory protein 1)

chr5_+_147763539 0.414 ENST00000296701.6
ENST00000394370.3
FBXO38

F-box protein 38

chr10_+_77056134 0.412 ENST00000528121.1
ENST00000416398.1
ZNF503-AS1

ZNF503 antisense RNA 1

chr13_-_20805109 0.412 ENST00000241124.6
GJB6
gap junction protein, beta 6, 30kDa
chr16_-_2205352 0.411 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr5_+_892745 0.408 ENST00000166345.3
TRIP13
thyroid hormone receptor interactor 13
chr20_+_19997948 0.407 ENST00000310450.4
ENST00000398602.2
NAA20

N(alpha)-acetyltransferase 20, NatB catalytic subunit

chr19_-_15343191 0.402 ENST00000221730.3
EPHX3
epoxide hydrolase 3
chr5_+_86564739 0.399 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1


RAS p21 protein activator (GTPase activating protein) 1


chr2_+_220110177 0.399 ENST00000409638.3
ENST00000396738.2
ENST00000409516.3
STK16


serine/threonine kinase 16


chr1_+_65886244 0.397 ENST00000344610.8
LEPR
leptin receptor
chr4_-_68566832 0.396 ENST00000420827.2
ENST00000322244.5
UBA6

ubiquitin-like modifier activating enzyme 6

chr9_-_136242909 0.396 ENST00000371991.3
ENST00000545297.1
SURF4

surfeit 4

chr5_+_137801160 0.396 ENST00000239938.4
EGR1
early growth response 1
chr11_-_64085533 0.392 ENST00000544844.1
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr5_-_138862326 0.391 ENST00000330794.4
TMEM173
transmembrane protein 173
chr4_-_39033963 0.387 ENST00000381938.3
TMEM156
transmembrane protein 156
chr10_-_98031265 0.385 ENST00000224337.5
ENST00000371176.2
BLNK

B-cell linker

chr14_-_21979428 0.381 ENST00000538267.1
ENST00000298717.4
METTL3

methyltransferase like 3

chr20_-_48532046 0.380 ENST00000543716.1
SPATA2
spermatogenesis associated 2
chr9_-_115095851 0.379 ENST00000343327.2
PTBP3
polypyrimidine tract binding protein 3
chr19_-_50143452 0.376 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr2_+_113342163 0.373 ENST00000409719.1
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr2_-_119605253 0.373 ENST00000295206.6
EN1
engrailed homeobox 1
chr16_-_23652570 0.373 ENST00000261584.4
PALB2
partner and localizer of BRCA2
chr4_+_153701081 0.369 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ARFIP1




ADP-ribosylation factor interacting protein 1




chr4_+_177241094 0.364 ENST00000503362.1
SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr9_+_106856541 0.359 ENST00000286398.7
ENST00000440179.1
ENST00000374793.3
SMC2


structural maintenance of chromosomes 2


chr5_+_96079240 0.356 ENST00000515663.1
CAST
calpastatin
chr15_-_82555000 0.354 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
EFTUD1


elongation factor Tu GTP binding domain containing 1


chrX_+_47444613 0.353 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr5_+_158690089 0.352 ENST00000296786.6
UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr1_-_10003372 0.351 ENST00000377223.1
ENST00000541052.1
ENST00000377213.1
LZIC


leucine zipper and CTNNBIP1 domain containing


chr17_+_67410832 0.351 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr8_-_55014415 0.350 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
LYPLA1



lysophospholipase I



chrX_-_15872914 0.345 ENST00000380291.1
ENST00000545766.1
ENST00000421527.2
ENST00000329235.2
AP1S2



adaptor-related protein complex 1, sigma 2 subunit



chr3_-_37217756 0.344 ENST00000440230.1
ENST00000421276.2
ENST00000421307.1
ENST00000354379.4
LRRFIP2



leucine rich repeat (in FLII) interacting protein 2



chr2_-_201753980 0.343 ENST00000443398.1
ENST00000286175.8
ENST00000409449.1
PPIL3


peptidylprolyl isomerase (cyclophilin)-like 3


chrX_-_40594755 0.342 ENST00000324817.1
MED14
mediator complex subunit 14
chr14_+_21458127 0.342 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
METTL17





methyltransferase like 17





chr7_-_32931623 0.341 ENST00000452926.1
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr5_-_40835303 0.340 ENST00000509877.1
ENST00000508493.1
ENST00000274242.5
RPL37


ribosomal protein L37


chr17_+_6544356 0.338 ENST00000574838.1
TXNDC17
thioredoxin domain containing 17
chr17_-_48450534 0.330 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
MRPL27


mitochondrial ribosomal protein L27


chr2_+_118846008 0.327 ENST00000245787.4
INSIG2
insulin induced gene 2
chr19_-_51014345 0.326 ENST00000391815.3
ENST00000594350.1
ENST00000601423.1
JOSD2


Josephin domain containing 2


chr2_-_136743169 0.326 ENST00000264161.4
DARS
aspartyl-tRNA synthetase
chr3_-_28390581 0.326 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr19_-_45657028 0.324 ENST00000429338.1
ENST00000589776.1
NKPD1

NTPase, KAP family P-loop domain containing 1

chr4_-_153601136 0.322 ENST00000504064.1
ENST00000304385.3
TMEM154

transmembrane protein 154

chr2_+_113342011 0.319 ENST00000324913.5
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr10_+_18948311 0.317 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr2_-_201753859 0.317 ENST00000409361.1
ENST00000392283.4
PPIL3

peptidylprolyl isomerase (cyclophilin)-like 3

chr9_+_75136717 0.317 ENST00000297784.5
TMC1
transmembrane channel-like 1
chrX_-_153775426 0.317 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr1_+_99127265 0.315 ENST00000306121.3
SNX7
sorting nexin 7
chr10_-_98031310 0.313 ENST00000427367.2
ENST00000413476.2
BLNK

B-cell linker

chr1_+_28655505 0.309 ENST00000373842.4
ENST00000398997.2
MED18

mediator complex subunit 18

chr17_+_18218587 0.307 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr7_-_1543981 0.306 ENST00000404767.3
INTS1
integrator complex subunit 1
chr17_+_1945301 0.305 ENST00000572195.1
OVCA2
ovarian tumor suppressor candidate 2
chr1_-_52870059 0.304 ENST00000371566.1
ORC1
origin recognition complex, subunit 1
chr1_-_150208412 0.302 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E



acidic (leucine-rich) nuclear phosphoprotein 32 family, member E



chr1_-_155270770 0.300 ENST00000392414.3
PKLR
pyruvate kinase, liver and RBC
chr2_+_28618532 0.298 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr2_+_65215604 0.296 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr13_-_33924755 0.295 ENST00000439831.1
ENST00000567873.1
STARD13

StAR-related lipid transfer (START) domain containing 13

chr2_-_201753717 0.295 ENST00000409264.2
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr17_+_29421987 0.294 ENST00000431387.4
NF1
neurofibromin 1
chr4_+_20702059 0.292 ENST00000444671.2
ENST00000510700.1
ENST00000506745.1
ENST00000514663.1
ENST00000509469.1
ENST00000515339.1
ENST00000513861.1
ENST00000502374.1
ENST00000538990.1
ENST00000511160.1
ENST00000504630.1
ENST00000513590.1
ENST00000514292.1
ENST00000502938.1
ENST00000509625.1
ENST00000505160.1
ENST00000507634.1
ENST00000513459.1
ENST00000511089.1
PACRGL


















PARK2 co-regulated-like


















chr1_+_99127225 0.292 ENST00000370189.5
ENST00000529992.1
SNX7

sorting nexin 7

chr1_+_154947126 0.291 ENST00000368439.1
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr13_+_98605902 0.290 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5







importin 5







chr11_+_47270475 0.290 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
NR1H3



nuclear receptor subfamily 1, group H, member 3



chr9_+_37485932 0.290 ENST00000377798.4
ENST00000442009.2
POLR1E

polymerase (RNA) I polypeptide E, 53kDa

chr4_-_152149033 0.290 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr1_+_222886694 0.290 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BROX


BRO1 domain and CAAX motif containing


chr12_+_100594557 0.287 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6


ARP6 actin-related protein 6 homolog (yeast)


chr11_+_62529008 0.287 ENST00000301788.7
ENST00000533442.1
POLR2G

polymerase (RNA) II (DNA directed) polypeptide G

chr4_-_39034542 0.287 ENST00000344606.6
TMEM156
transmembrane protein 156
chr9_+_37486005 0.286 ENST00000377792.3
POLR1E
polymerase (RNA) I polypeptide E, 53kDa
chr6_-_41254403 0.285 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
TREM1



triggering receptor expressed on myeloid cells 1



chr5_+_271752 0.284 ENST00000505221.1
ENST00000509581.1
ENST00000507528.1
PDCD6


programmed cell death 6


chr1_+_235530675 0.284 ENST00000366601.3
ENST00000406207.1
ENST00000543662.1
TBCE


tubulin folding cofactor E


chr2_+_85839218 0.282 ENST00000448971.1
ENST00000442708.1
ENST00000450066.2
USP39


ubiquitin specific peptidase 39


chr11_+_62432777 0.281 ENST00000532971.1
METTL12
methyltransferase like 12
chr14_+_75179840 0.279 ENST00000554590.1
ENST00000341162.4
ENST00000534938.2
ENST00000553615.1
FCF1



FCF1 rRNA-processing protein



chr5_+_148724993 0.279 ENST00000513661.1
ENST00000329271.3
ENST00000416916.2
GRPEL2


GrpE-like 2, mitochondrial (E. coli)


chr17_+_48450575 0.278 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1


essential meiotic structure-specific endonuclease 1


chr11_+_47270436 0.277 ENST00000395397.3
ENST00000405576.1
NR1H3

nuclear receptor subfamily 1, group H, member 3

chr5_-_37371163 0.276 ENST00000513532.1
NUP155
nucleoporin 155kDa
chr19_+_11039391 0.276 ENST00000270502.6
C19orf52
chromosome 19 open reading frame 52
chrX_-_119695279 0.275 ENST00000336592.6
CUL4B
cullin 4B
chr22_-_29949634 0.273 ENST00000397872.1
ENST00000397871.1
ENST00000440771.1
THOC5


THO complex 5


chr7_-_99006443 0.272 ENST00000350498.3
PDAP1
PDGFA associated protein 1
chr17_+_6544328 0.272 ENST00000570330.1
TXNDC17
thioredoxin domain containing 17
chr1_+_110091189 0.272 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr3_-_42642560 0.272 ENST00000417572.1
SEC22C
SEC22 vesicle trafficking protein homolog C (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.6 2.5 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.5 1.5 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4 1.9 GO:0044565 dendritic cell proliferation(GO:0044565)
0.3 1.0 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.3 0.9 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 0.3 GO:0016568 chromatin modification(GO:0016568)
0.3 2.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.3 0.8 GO:0031938 regulation of chromatin silencing at telomere(GO:0031938)
0.2 1.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.2 2.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 0.6 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2 1.0 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.2 0.6 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 1.0 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 0.7 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2 0.7 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 0.5 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 0.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 1.0 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2 0.5 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 0.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 0.6 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.6 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.4 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.4 GO:2000705 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.4 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.7 GO:0021764 amygdala development(GO:0021764)
0.1 1.0 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.3 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 1.6 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 1.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.3 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.2 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.1 0.7 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.2 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 0.5 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.4 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.4 GO:0097338 response to clozapine(GO:0097338)
0.1 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.3 GO:0032526 response to retinoic acid(GO:0032526)
0.1 3.5 GO:0043486 histone exchange(GO:0043486)
0.1 0.2 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.2 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.2 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.3 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.1 0.2 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 0.1 GO:1903423 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.1 0.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.9 GO:0045008 depyrimidination(GO:0045008)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.2 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.2 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0015811 L-alanine transport(GO:0015808) L-cystine transport(GO:0015811)
0.0 0.9 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.1 GO:2000823 regulation of androgen receptor activity(GO:2000823) positive regulation of androgen receptor activity(GO:2000825)
0.0 0.5 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.3 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.3 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.6 GO:0075713 establishment of integrated proviral latency(GO:0075713)
0.0 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.8 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.5 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.3 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.2 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.1 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.5 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 1.5 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.2 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 1.0 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.3 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043) positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.7 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.4 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 0.1 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.7 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.2 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 1.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.6 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0034443 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.2 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.0 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.0 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.0 GO:0033590 response to cobalamin(GO:0033590)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.0 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.0 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.1 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.0 GO:0071106 coenzyme A transport(GO:0015880) FAD transport(GO:0015883) coenzyme A transmembrane transport(GO:0035349) FAD transmembrane transport(GO:0035350) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.4 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.3 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0097149 centralspindlin complex(GO:0097149)
0.3 1.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.3 1.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 0.6 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.2 0.5 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 1.0 GO:0000796 condensin complex(GO:0000796)
0.2 1.5 GO:0008278 cohesin complex(GO:0008278)
0.1 0.6 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.1 0.4 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.5 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.4 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 1.6 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.7 GO:0031298 replication fork protection complex(GO:0031298)
0.1 1.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.6 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.7 GO:0070847 core mediator complex(GO:0070847)
0.1 0.3 GO:0019034 viral replication complex(GO:0019034)
0.1 1.8 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 0.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.2 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 2.1 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.8 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.2 GO:1990923 PET complex(GO:1990923)
0.1 0.2 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 1.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.2 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.6 GO:0043073 male germ cell nucleus(GO:0001673) germ cell nucleus(GO:0043073)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.9 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 1.6 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.2 GO:0005694 chromosome(GO:0005694)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 3.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.4 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 1.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.0 1.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.1 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.3 1.0 GO:0002113 interleukin-33 binding(GO:0002113)
0.3 1.0 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.3 1.7 GO:0032089 NACHT domain binding(GO:0032089)
0.3 1.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 1.8 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 1.8 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.7 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 0.5 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.2 0.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.4 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.5 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.6 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.4 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.3 GO:0001003 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.4 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.5 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.2 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 0.2 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.4 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.2 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.3 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-cystine transmembrane transporter activity(GO:0015184) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.6 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 2.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.5 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 5.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.3 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.0 GO:0004917 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.0 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) FAD transmembrane transporter activity(GO:0015230) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 9.2 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.0 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.7 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.4 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 ST_TUMOR_NECROSIS_FACTOR_PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 1.0 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.1 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.8 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.7 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.5 PID_CD40_PATHWAY CD40/CD40L signaling
0.0 0.3 SA_G1_AND_S_PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.9 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.3 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID_IL1_PATHWAY IL1-mediated signaling events
0.0 0.3 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.4 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 REACTOME_KINESINS Genes involved in Kinesins
0.1 1.8 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 1.3 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.4 REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 1.1 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.1 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.6 REACTOME_INTEGRATION_OF_PROVIRUS Genes involved in Integration of provirus
0.0 1.3 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.2 REACTOME_REGULATION_OF_SIGNALING_BY_CBL Genes involved in Regulation of signaling by CBL
0.0 0.8 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.8 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.7 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.4 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME_ENOS_ACTIVATION_AND_REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.9 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.9 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.2 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 1.6 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.9 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.2 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.1 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME_RNA_POL_III_TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.0 0.3 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME_DOUBLE_STRAND_BREAK_REPAIR Genes involved in Double-Strand Break Repair
0.0 0.1 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion