Motif ID: E2F4

Z-value: 0.981


Transcription factors associated with E2F4:

Gene SymbolEntrez IDGene Name
E2F4 ENSG00000205250.4 E2F4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
E2F4hg19_v2_chr16_+_67226019_67226127-0.048.4e-01Click!


Activity profile for motif E2F4.

activity profile for motif E2F4


Sorted Z-values histogram for motif E2F4

Sorted Z-values for motif E2F4



Network of associatons between targets according to the STRING database.



First level regulatory network of E2F4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrY_+_22737678 2.368 ENST00000382772.3
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chr14_-_55658323 2.029 ENST00000554067.1
ENST00000247191.2
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chrY_+_22737604 1.970 ENST00000361365.2
EIF1AY
eukaryotic translation initiation factor 1A, Y-linked
chr2_+_10262857 1.853 ENST00000304567.5
RRM2
ribonucleotide reductase M2
chr1_+_91966656 1.745 ENST00000428239.1
ENST00000426137.1
CDC7

cell division cycle 7

chr1_+_91966384 1.741 ENST00000430031.2
ENST00000234626.6
CDC7

cell division cycle 7

chr17_-_76183111 1.703 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
TK1



thymidine kinase 1, soluble



chr19_-_48673580 1.581 ENST00000427526.2
LIG1
ligase I, DNA, ATP-dependent
chr19_-_48673552 1.554 ENST00000536218.1
ENST00000596549.1
LIG1

ligase I, DNA, ATP-dependent

chr12_-_77459306 1.536 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F7



E2F transcription factor 7



chr8_-_95907423 1.517 ENST00000396133.3
ENST00000308108.4
CCNE2

cyclin E2

chr15_+_91260552 1.477 ENST00000355112.3
ENST00000560509.1
BLM

Bloom syndrome, RecQ helicase-like

chr5_+_892745 1.401 ENST00000166345.3
TRIP13
thyroid hormone receptor interactor 13
chr11_-_64851496 1.301 ENST00000404147.3
ENST00000275517.3
CDCA5

cell division cycle associated 5

chr22_+_19467261 1.183 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45



cell division cycle 45



chr7_-_21985489 1.178 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
CDCA7L



cell division cycle associated 7-like



chr6_+_126661253 1.159 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
CENPW


centromere protein W


chr5_-_127873659 1.108 ENST00000262464.4
FBN2
fibrillin 2
chr10_-_70231639 1.081 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA2



DNA replication helicase/nuclease 2



chr4_-_185655278 1.049 ENST00000281453.5
MLF1IP
centromere protein U
chr1_-_197115818 1.043 ENST00000367409.4
ENST00000294732.7
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr14_-_50154921 1.035 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2



polymerase (DNA directed), epsilon 2, accessory subunit



chr8_+_48873453 1.029 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr8_+_48873479 1.020 ENST00000262105.2
MCM4
minichromosome maintenance complex component 4
chr11_-_123525289 1.012 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B


sodium channel, voltage-gated, type III, beta subunit


chr13_+_34392185 0.960 ENST00000380071.3
RFC3
replication factor C (activator 1) 3, 38kDa
chr1_-_26185844 0.927 ENST00000538789.1
ENST00000374298.3
AUNIP

aurora kinase A and ninein interacting protein

chr9_-_35080013 0.918 ENST00000378643.3
FANCG
Fanconi anemia, complementation group G
chr12_-_56843161 0.904 ENST00000554616.1
ENST00000553532.1
ENST00000229201.4
TIMELESS


timeless circadian clock


chr12_-_57146095 0.903 ENST00000550770.1
ENST00000338193.6
PRIM1

primase, DNA, polypeptide 1 (49kDa)

chr20_+_42295745 0.869 ENST00000396863.4
ENST00000217026.4
MYBL2

v-myb avian myeloblastosis viral oncogene homolog-like 2

chr2_-_203736452 0.861 ENST00000419460.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr4_+_154265784 0.857 ENST00000240488.3
MND1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr7_-_21985656 0.839 ENST00000406877.3
CDCA7L
cell division cycle associated 7-like
chr11_+_58910295 0.827 ENST00000420244.1
FAM111A
family with sequence similarity 111, member A
chr19_-_14016877 0.824 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
C19orf57


chromosome 19 open reading frame 57


chr8_+_27491381 0.823 ENST00000337221.4
SCARA3
scavenger receptor class A, member 3
chr22_-_42343117 0.820 ENST00000407253.3
ENST00000215980.5
CENPM

centromere protein M

chr22_-_42342692 0.814 ENST00000404067.1
ENST00000402338.1
CENPM

centromere protein M

chr17_-_34890759 0.805 ENST00000431794.3
MYO19
myosin XIX
chr15_+_48624300 0.805 ENST00000455976.2
ENST00000559540.1
DUT

deoxyuridine triphosphatase

chr4_+_178230985 0.803 ENST00000264596.3
NEIL3
nei endonuclease VIII-like 3 (E. coli)
chr9_+_35732312 0.784 ENST00000353704.2
CREB3
cAMP responsive element binding protein 3
chr1_-_229761717 0.773 ENST00000366675.3
ENST00000258281.2
ENST00000366674.1
TAF5L


TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa


chr4_+_128802016 0.770 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
PLK4



polo-like kinase 4



chr7_-_99698338 0.766 ENST00000354230.3
ENST00000425308.1
MCM7

minichromosome maintenance complex component 7

chr12_-_57472522 0.740 ENST00000379391.3
ENST00000300128.4
TMEM194A

transmembrane protein 194A

chr3_+_160117418 0.740 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4









structural maintenance of chromosomes 4









chr17_-_41277317 0.733 ENST00000497488.1
ENST00000489037.1
ENST00000470026.1
ENST00000586385.1
ENST00000591534.1
ENST00000591849.1
BRCA1





breast cancer 1, early onset





chr5_-_43313574 0.729 ENST00000325110.6
ENST00000433297.2
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr16_+_699319 0.720 ENST00000549091.1
ENST00000293879.4
WDR90

WD repeat domain 90

chr17_-_30185946 0.719 ENST00000579741.1
COPRS
coordinator of PRMT5, differentiation stimulator
chr6_+_151561506 0.711 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr12_+_49717019 0.693 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
TROAP







trophinin associated protein







chr20_+_37554955 0.678 ENST00000217429.4
FAM83D
family with sequence similarity 83, member D
chr11_-_118966167 0.668 ENST00000530167.1
H2AFX
H2A histone family, member X
chr4_+_74702214 0.668 ENST00000226317.5
ENST00000515050.1
CXCL6

chemokine (C-X-C motif) ligand 6

chr14_+_50065376 0.651 ENST00000298288.6
LRR1
leucine rich repeat protein 1
chr17_-_41277370 0.651 ENST00000476777.1
ENST00000491747.2
ENST00000478531.1
ENST00000477152.1
ENST00000357654.3
ENST00000493795.1
ENST00000493919.1
BRCA1






breast cancer 1, early onset






chr17_-_41277467 0.628 ENST00000494123.1
ENST00000346315.3
ENST00000309486.4
ENST00000468300.1
ENST00000354071.3
ENST00000352993.3
ENST00000471181.2
BRCA1






breast cancer 1, early onset






chr12_+_49717081 0.619 ENST00000547807.1
ENST00000551567.1
TROAP

trophinin associated protein

chr11_+_58910201 0.613 ENST00000528737.1
FAM111A
family with sequence similarity 111, member A
chr6_-_62996066 0.602 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr10_+_120967072 0.597 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr9_-_124990680 0.563 ENST00000541397.2
ENST00000560485.1
LHX6

LIM homeobox 6

chr2_-_26205340 0.558 ENST00000264712.3
KIF3C
kinesin family member 3C
chr12_+_102513950 0.554 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP



PARP1 binding protein



chr4_-_73434498 0.552 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr4_+_56815102 0.544 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr1_+_173793777 0.543 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr1_-_47779762 0.535 ENST00000371877.3
ENST00000360380.3
ENST00000337817.5
ENST00000447475.2
STIL



SCL/TAL1 interrupting locus



chr15_-_50647370 0.533 ENST00000558970.1
ENST00000396464.3
ENST00000560825.1
GABPB1


GA binding protein transcription factor, beta subunit 1


chr15_+_40987327 0.528 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51




RAD51 recombinase




chr21_-_33651324 0.527 ENST00000290130.3
MIS18A
MIS18 kinetochore protein A
chr1_+_28844778 0.527 ENST00000411533.1
RCC1
regulator of chromosome condensation 1
chr9_-_124991124 0.523 ENST00000394319.4
ENST00000340587.3
LHX6

LIM homeobox 6

chr14_+_50065459 0.508 ENST00000318317.4
LRR1
leucine rich repeat protein 1
chr6_+_167412835 0.500 ENST00000349556.4
FGFR1OP
FGFR1 oncogene partner
chr3_-_148804275 0.489 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF



helicase-like transcription factor



chr15_+_42841008 0.478 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS2



HAUS augmin-like complex, subunit 2



chr12_+_8850471 0.477 ENST00000535829.1
ENST00000357529.3
RIMKLB

ribosomal modification protein rimK-like family member B

chr18_+_33767473 0.470 ENST00000261326.5
MOCOS
molybdenum cofactor sulfurase
chr6_+_57182400 0.468 ENST00000607273.1
PRIM2
primase, DNA, polypeptide 2 (58kDa)
chr8_-_103136481 0.466 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
NCALD






neurocalcin delta






chr2_+_179059365 0.459 ENST00000190611.4
OSBPL6
oxysterol binding protein-like 6
chr8_-_124408652 0.457 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr12_+_102514019 0.456 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARPBP


PARP1 binding protein


chr4_-_120548779 0.454 ENST00000264805.5
PDE5A
phosphodiesterase 5A, cGMP-specific
chr20_+_47662805 0.450 ENST00000262982.2
ENST00000542325.1
CSE1L

CSE1 chromosome segregation 1-like (yeast)

chr1_+_65210772 0.443 ENST00000371072.4
ENST00000294428.3
RAVER2

ribonucleoprotein, PTB-binding 2

chr1_+_44398943 0.440 ENST00000372359.5
ENST00000414809.3
ARTN

artemin

chr19_+_50887585 0.439 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1



polymerase (DNA directed), delta 1, catalytic subunit



chr14_+_105219437 0.430 ENST00000329967.6
ENST00000347067.5
ENST00000553810.1
SIVA1


SIVA1, apoptosis-inducing factor


chr5_-_79950371 0.430 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
DHFR


dihydrofolate reductase


chr10_-_118764862 0.426 ENST00000260777.10
KIAA1598
KIAA1598
chr11_+_82612740 0.421 ENST00000524921.1
ENST00000528759.1
ENST00000525361.1
ENST00000430323.2
ENST00000533655.1
ENST00000532764.1
ENST00000532589.1
ENST00000525388.1
C11orf82







chromosome 11 open reading frame 82







chr3_+_10068095 0.419 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2



Fanconi anemia, complementation group D2



chr5_+_36152179 0.418 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
SKP2


S-phase kinase-associated protein 2, E3 ubiquitin protein ligase


chr11_-_95657231 0.403 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
MTMR2



myotubularin related protein 2



chr16_+_838614 0.403 ENST00000262315.9
ENST00000455171.2
CHTF18

CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)

chr17_-_30185971 0.400 ENST00000378634.2
COPRS
coordinator of PRMT5, differentiation stimulator
chr19_-_10444188 0.399 ENST00000293677.6
RAVER1
ribonucleoprotein, PTB-binding 1
chr20_-_35402123 0.398 ENST00000373740.3
ENST00000426836.1
ENST00000373745.3
ENST00000448110.2
ENST00000438549.1
ENST00000447406.1
ENST00000373750.4
ENST00000373734.4
DSN1







DSN1, MIS12 kinetochore complex component







chr20_-_35724388 0.386 ENST00000344359.3
ENST00000373664.3
RBL1

retinoblastoma-like 1 (p107)

chr5_+_14664762 0.384 ENST00000284274.4
FAM105B
family with sequence similarity 105, member B
chr1_+_44399466 0.381 ENST00000498139.2
ENST00000491846.1
ARTN

artemin

chr2_-_38978492 0.379 ENST00000409276.1
ENST00000446327.2
ENST00000313117.6
SRSF7


serine/arginine-rich splicing factor 7


chr9_+_131709966 0.372 ENST00000372577.2
NUP188
nucleoporin 188kDa
chr15_-_50647347 0.371 ENST00000220429.8
ENST00000429662.2
GABPB1

GA binding protein transcription factor, beta subunit 1

chr9_-_131418944 0.366 ENST00000419989.1
ENST00000451652.1
ENST00000372715.2
WDR34


WD repeat domain 34


chr16_-_49315731 0.362 ENST00000219197.6
CBLN1
cerebellin 1 precursor
chr5_+_156887027 0.360 ENST00000435489.2
ENST00000311946.7
NIPAL4

NIPA-like domain containing 4

chr7_-_73668692 0.347 ENST00000352131.3
ENST00000055077.3
RFC2

replication factor C (activator 1) 2, 40kDa

chr11_+_31531291 0.344 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4


elongator acetyltransferase complex subunit 4


chr19_-_31840438 0.343 ENST00000240587.4
TSHZ3
teashirt zinc finger homeobox 3
chr5_+_36152091 0.342 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr15_-_50647274 0.340 ENST00000543881.1
GABPB1
GA binding protein transcription factor, beta subunit 1
chrX_+_30671476 0.336 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
GK




glycerol kinase




chr14_+_21538517 0.332 ENST00000298693.3
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chrX_+_133594168 0.330 ENST00000298556.7
HPRT1
hypoxanthine phosphoribosyltransferase 1
chr14_+_53019993 0.326 ENST00000542169.2
ENST00000555622.1
GPR137C

G protein-coupled receptor 137C

chr5_+_36152163 0.325 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr1_+_173793641 0.321 ENST00000361951.4
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr21_-_44496441 0.321 ENST00000359624.3
ENST00000352178.5
CBS

cystathionine-beta-synthase

chr9_-_77567743 0.318 ENST00000376854.5
C9orf40
chromosome 9 open reading frame 40
chr10_+_82116529 0.315 ENST00000411538.1
ENST00000256039.2
DYDC2

DPY30 domain containing 2

chr2_+_48010312 0.311 ENST00000540021.1
MSH6
mutS homolog 6
chr17_+_77751931 0.310 ENST00000310942.4
ENST00000269399.5
CBX2

chromobox homolog 2

chr2_+_47630255 0.310 ENST00000406134.1
MSH2
mutS homolog 2
chr13_+_95254085 0.308 ENST00000376958.4
GPR180
G protein-coupled receptor 180
chr6_-_139308777 0.306 ENST00000529597.1
ENST00000415951.2
ENST00000367663.4
ENST00000409812.2
REPS1



RALBP1 associated Eps domain containing 1



chr6_+_135502466 0.300 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr4_-_122872909 0.300 ENST00000379645.3
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr19_+_55795493 0.300 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr6_-_19804973 0.298 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2


RP4-625H18.2


chr5_+_149737202 0.295 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1









Treacher Collins-Franceschetti syndrome 1









chr2_-_17935059 0.293 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
SMC6


structural maintenance of chromosomes 6


chr2_+_48010221 0.291 ENST00000234420.5
MSH6
mutS homolog 6
chr2_-_128785688 0.286 ENST00000259234.6
SAP130
Sin3A-associated protein, 130kDa
chr4_-_120549163 0.286 ENST00000394439.1
ENST00000420633.1
PDE5A

phosphodiesterase 5A, cGMP-specific

chr7_+_77428149 0.282 ENST00000415251.2
ENST00000275575.7
PHTF2

putative homeodomain transcription factor 2

chr4_+_155665123 0.282 ENST00000336356.3
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr4_+_175204818 0.280 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr4_+_331578 0.280 ENST00000512994.1
ZNF141
zinc finger protein 141
chr6_+_135502408 0.277 ENST00000341911.5
ENST00000442647.2
ENST00000316528.8
MYB


v-myb avian myeloblastosis viral oncogene homolog


chr2_+_47630108 0.274 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2


mutS homolog 2


chr6_-_139309378 0.265 ENST00000450536.2
ENST00000258062.5
REPS1

RALBP1 associated Eps domain containing 1

chrX_+_100353153 0.265 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
CENPI



centromere protein I



chr6_-_110012380 0.264 ENST00000424296.2
ENST00000341338.6
ENST00000368948.2
ENST00000285397.5
AK9



adenylate kinase 9



chr19_+_50180317 0.264 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr7_+_77428066 0.263 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2


putative homeodomain transcription factor 2


chr9_+_17134980 0.263 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr15_-_42840961 0.260 ENST00000563454.1
ENST00000397130.3
ENST00000570160.1
ENST00000323443.2
LRRC57



leucine rich repeat containing 57



chr13_-_113862948 0.260 ENST00000375457.2
ENST00000375477.1
ENST00000246505.5
ENST00000337344.4
ENST00000375479.2
PCID2




PCI domain containing 2




chr9_-_23821842 0.259 ENST00000544538.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr9_+_131182697 0.257 ENST00000372838.4
ENST00000411852.1
CERCAM

cerebral endothelial cell adhesion molecule

chr11_-_118972575 0.255 ENST00000432443.2
DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr1_+_173837488 0.251 ENST00000427304.1
ENST00000432989.1
ENST00000367702.1
ZBTB37


zinc finger and BTB domain containing 37


chr1_+_10490779 0.248 ENST00000477755.1
APITD1
apoptosis-inducing, TAF9-like domain 1
chr3_+_128598433 0.246 ENST00000308982.7
ENST00000514336.1
ACAD9

acyl-CoA dehydrogenase family, member 9

chr2_+_68384976 0.244 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr1_+_240255166 0.244 ENST00000319653.9
FMN2
formin 2
chr14_+_21538429 0.243 ENST00000298694.4
ENST00000555038.1
ARHGEF40

Rho guanine nucleotide exchange factor (GEF) 40

chr2_-_133427767 0.240 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chr16_-_67693846 0.239 ENST00000602850.1
ACD
adrenocortical dysplasia homolog (mouse)
chr15_-_100273544 0.237 ENST00000409796.1
ENST00000545021.1
ENST00000344791.2
ENST00000332728.4
ENST00000450512.1
LYSMD4




LysM, putative peptidoglycan-binding, domain containing 4




chr11_-_119234876 0.237 ENST00000525735.1
USP2
ubiquitin specific peptidase 2
chr19_+_13049413 0.236 ENST00000316448.5
ENST00000588454.1
CALR

calreticulin

chr14_+_53019822 0.236 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr2_+_204192942 0.233 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr11_-_31531121 0.232 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L






IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)






chr8_+_124084899 0.223 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1D31






TBC1 domain family, member 31






chr8_-_101157680 0.223 ENST00000428847.2
FBXO43
F-box protein 43
chr2_-_68384603 0.219 ENST00000406245.2
ENST00000409164.1
ENST00000295121.6
WDR92


WD repeat domain 92


chr1_+_10490441 0.218 ENST00000309048.3
ENST00000470413.2
APITD1
APITD1-CORT
apoptosis-inducing, TAF9-like domain 1
APITD1-CORT readthrough
chr1_+_28844648 0.215 ENST00000373832.1
ENST00000373831.3
RCC1

regulator of chromosome condensation 1

chr2_+_178077477 0.215 ENST00000411529.2
ENST00000435711.1
HNRNPA3

heterogeneous nuclear ribonucleoprotein A3

chr12_-_102513843 0.214 ENST00000551744.2
ENST00000552283.1
NUP37

nucleoporin 37kDa

chr22_+_20105012 0.206 ENST00000331821.3
ENST00000411892.1
RANBP1

RAN binding protein 1

chr5_-_179636153 0.201 ENST00000361132.4
RASGEF1C
RasGEF domain family, member 1C
chr17_+_73008755 0.201 ENST00000584208.1
ENST00000301585.5
ICT1

immature colon carcinoma transcript 1

chr2_+_154728426 0.201 ENST00000392825.3
ENST00000434213.1
GALNT13

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)

chr7_-_30544405 0.198 ENST00000409390.1
ENST00000409144.1
ENST00000005374.6
ENST00000409436.1
ENST00000275428.4
GGCT




gamma-glutamylcyclotransferase




chr16_+_11439286 0.197 ENST00000312499.5
ENST00000576027.1
RMI2

RecQ mediated genome instability 2

chr1_+_10490127 0.197 ENST00000602787.1
ENST00000602296.1
ENST00000400900.2
APITD1

APITD1-CORT
apoptosis-inducing, TAF9-like domain 1

APITD1-CORT readthrough
chr12_+_56521840 0.196 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr18_+_54318616 0.195 ENST00000254442.3
WDR7
WD repeat domain 7
chr5_-_137548997 0.194 ENST00000505120.1
ENST00000394886.2
ENST00000394884.3
CDC23


cell division cycle 23


chr16_-_67694129 0.194 ENST00000602320.1
ACD
adrenocortical dysplasia homolog (mouse)
chr1_+_84543734 0.194 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_-_33759541 0.194 ENST00000468888.2
CLASP2
cytoplasmic linker associated protein 2
chr10_+_92631709 0.191 ENST00000413330.1
ENST00000277882.3
RPP30

ribonuclease P/MRP 30kDa subunit

chr3_-_33759699 0.190 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
CLASP2


cytoplasmic linker associated protein 2


chr16_-_23568651 0.189 ENST00000563232.1
ENST00000563459.1
ENST00000449606.1
EARS2


glutamyl-tRNA synthetase 2, mitochondrial


chr3_+_180630090 0.189 ENST00000357559.4
ENST00000305586.7
FXR1

fragile X mental retardation, autosomal homolog 1

chr2_-_11484710 0.188 ENST00000315872.6
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr5_-_149682447 0.186 ENST00000328668.7
ARSI
arylsulfatase family, member I
chr17_-_74722536 0.186 ENST00000585429.1
JMJD6
jumonji domain containing 6
chr7_-_32931623 0.184 ENST00000452926.1
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr2_+_17935119 0.182 ENST00000317402.7
GEN1
GEN1 Holliday junction 5' flap endonuclease

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.2 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.7 2.0 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.7 1.3 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.6 4.7 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.6 1.7 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.4 1.7 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.3 1.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.3 2.0 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.3 2.0 GO:0072757 cellular response to camptothecin(GO:0072757)
0.3 1.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.3 2.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.3 0.8 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.3 1.8 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 1.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 1.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.2 0.6 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.2 0.9 GO:0072719 cellular response to cisplatin(GO:0072719)
0.2 0.5 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 1.0 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 0.8 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.2 0.8 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.2 0.8 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 1.4 GO:0007144 female meiosis I(GO:0007144)
0.1 1.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.7 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.4 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.6 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 1.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.3 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.8 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.3 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.1 1.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.4 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 3.6 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 2.6 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.3 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 1.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.1 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.4 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 0.5 GO:0033504 floor plate development(GO:0033504)
0.1 0.2 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.1 0.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 2.6 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.4 GO:0097338 response to clozapine(GO:0097338)
0.1 0.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.8 GO:0009650 UV protection(GO:0009650)
0.1 0.2 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.5 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.5 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.4 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.0 0.2 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.7 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.2 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.3 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 1.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.5 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.7 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:1904978 regulation of endosome organization(GO:1904978)
0.0 0.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:0097116 postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.3 GO:0044351 macropinocytosis(GO:0044351) phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.6 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 1.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0003169 coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.8 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 1.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0000732 strand displacement(GO:0000732)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.0 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.0 GO:0044691 tooth eruption(GO:0044691)
0.0 0.0 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.9 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.5 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.0 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.2 GO:0010212 response to ionizing radiation(GO:0010212)
0.0 0.3 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.7 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.4 1.2 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.4 1.5 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.4 1.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3 1.2 GO:0032301 MutSalpha complex(GO:0032301)
0.3 0.9 GO:0031523 Myb complex(GO:0031523)
0.2 1.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 1.8 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 2.8 GO:0042555 MCM complex(GO:0042555)
0.2 1.0 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 2.2 GO:0000800 lateral element(GO:0000800)
0.2 0.8 GO:0098536 deuterosome(GO:0098536)
0.1 2.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 1.3 GO:0008278 cohesin complex(GO:0008278)
0.1 2.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 1.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 1.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.7 GO:0000796 condensin complex(GO:0000796)
0.1 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.1 3.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.6 GO:0070187 telosome(GO:0070187)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 1.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0030914 STAGA complex(GO:0030914)
0.0 0.5 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 2.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)
0.0 2.9 GO:0001650 fibrillar center(GO:0001650)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.0 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.8 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 1.4 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0004797 thymidine kinase activity(GO:0004797)
0.4 1.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 1.4 GO:0003896 DNA primase activity(GO:0003896)
0.3 3.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.3 1.2 GO:0032143 single thymine insertion binding(GO:0032143)
0.3 2.3 GO:0000405 bubble DNA binding(GO:0000405)
0.3 0.8 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.2 3.4 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 0.8 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 0.6 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 0.9 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.2 1.0 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 1.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.3 GO:0050421 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1 0.5 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 0.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.8 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 1.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.2 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 2.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.4 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.2 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.1 1.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.3 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 3.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.0 GO:0008940 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.8 PID_FANCONI_PATHWAY Fanconi anemia pathway
0.0 0.8 PID_ATR_PATHWAY ATR signaling pathway
0.0 5.5 PID_E2F_PATHWAY E2F transcription factor network
0.0 0.9 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 2.0 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.2 PID_MYC_PATHWAY C-MYC pathway
0.0 0.8 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.5 PID_BARD1_PATHWAY BARD1 signaling events
0.0 2.1 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.5 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 2.4 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 0.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.4 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.3 PID_CONE_PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.3 5.8 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.2 7.6 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 3.4 REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR_OF_REPLICATION_INDEPENDENT_DOUBLE_STRAND_BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 3.0 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.1 2.4 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 2.6 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.1 1.6 REACTOME_FANCONI_ANEMIA_PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.1 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 4.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 2.3 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.4 REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.2 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines