Motif ID: CXXC1
Z-value: 1.130
Transcription factors associated with CXXC1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| CXXC1 | ENSG00000154832.10 | CXXC1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CXXC1 | hg19_v2_chr18_-_47813940_47814021 | 0.24 | 2.6e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 300 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.3 | GO:0006999 | nuclear pore organization(GO:0006999) |
| 0.1 | 3.5 | GO:0003341 | cilium movement(GO:0003341) |
| 0.0 | 2.4 | GO:0097031 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.2 | 1.7 | GO:0021943 | formation of radial glial scaffolds(GO:0021943) |
| 0.0 | 1.7 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.1 | 1.6 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.0 | 1.5 | GO:0042073 | intraciliary transport(GO:0042073) |
| 0.1 | 1.4 | GO:0036159 | inner dynein arm assembly(GO:0036159) |
| 0.1 | 1.2 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 0.1 | 1.2 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.1 | 1.2 | GO:0003084 | positive regulation of systemic arterial blood pressure(GO:0003084) |
| 0.1 | 1.2 | GO:0010826 | negative regulation of centrosome duplication(GO:0010826) |
| 0.0 | 1.2 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.0 | 1.2 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 1.2 | GO:0032729 | positive regulation of interferon-gamma production(GO:0032729) |
| 0.3 | 1.1 | GO:0005986 | sucrose biosynthetic process(GO:0005986) |
| 0.1 | 1.1 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
| 0.1 | 1.1 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
| 0.3 | 1.0 | GO:0003099 | vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099) |
| 0.1 | 1.0 | GO:0061470 | T follicular helper cell differentiation(GO:0061470) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 126 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.1 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
| 0.0 | 3.7 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 2.4 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 2.0 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 1.9 | GO:0036038 | MKS complex(GO:0036038) |
| 0.1 | 1.7 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 1.6 | GO:0005858 | axonemal dynein complex(GO:0005858) |
| 0.0 | 1.6 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.1 | 1.5 | GO:0097433 | dense body(GO:0097433) |
| 0.1 | 1.5 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 1.3 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 1.3 | GO:0045095 | keratin filament(GO:0045095) |
| 0.4 | 1.2 | GO:0001534 | radial spoke(GO:0001534) |
| 0.1 | 1.2 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.1 | 1.1 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.0 | 1.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 1.0 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 1.0 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 0.9 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.0 | 0.9 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 206 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.5 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 2.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 1.7 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 1.6 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.0 | 1.6 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.1 | 1.5 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 1.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 1.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 1.2 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.0 | 1.2 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.3 | 1.1 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 0.1 | 1.1 | GO:0019841 | retinol binding(GO:0019841) |
| 0.0 | 1.1 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.0 | 1.1 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.3 | 1.0 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) |
| 0.3 | 1.0 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 0.3 | 1.0 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 0.1 | 1.0 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.0 | 1.0 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.3 | 0.9 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
Gene overrepresentation in C2:CP category:
Showing 1 to 18 of 18 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
| 0.0 | 1.9 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
| 0.0 | 1.6 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.5 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
| 0.0 | 1.2 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
| 0.0 | 1.2 | PID_ERBB1_INTERNALIZATION_PATHWAY | Internalization of ErbB1 |
| 0.0 | 1.1 | ST_MYOCYTE_AD_PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.9 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.7 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.6 | PID_IL2_PI3K_PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 0.5 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.3 | ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.0 | 0.3 | ST_GRANULE_CELL_SURVIVAL_PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 0.3 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.2 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
| 0.0 | 0.2 | PID_TCR_RAS_PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 0.1 | PID_RANBP2_PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 0.1 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 56 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.2 | REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.0 | 2.4 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 1.6 | REACTOME_DNA_REPAIR | Genes involved in DNA Repair |
| 0.1 | 1.5 | REACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.0 | 1.5 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 1.4 | REACTOME_PLC_BETA_MEDIATED_EVENTS | Genes involved in PLC beta mediated events |
| 0.0 | 1.3 | REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.1 | 1.2 | REACTOME_REGULATED_PROTEOLYSIS_OF_P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.1 | 1.2 | REACTOME_XENOBIOTICS | Genes involved in Xenobiotics |
| 0.0 | 1.1 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.0 | 1.0 | REACTOME_COMPLEMENT_CASCADE | Genes involved in Complement cascade |
| 0.1 | 0.9 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 0.9 | REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.9 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.9 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.9 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.7 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.7 | REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.7 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 0.7 | REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | Genes involved in Amine ligand-binding receptors |
