Motif ID: CUX2

Z-value: 1.104


Transcription factors associated with CUX2:

Gene SymbolEntrez IDGene Name
CUX2 ENSG00000111249.9 CUX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CUX2hg19_v2_chr12_+_111471828_1114719750.029.2e-01Click!


Activity profile for motif CUX2.

activity profile for motif CUX2


Sorted Z-values histogram for motif CUX2

Sorted Z-values for motif CUX2



Network of associatons between targets according to the STRING database.



First level regulatory network of CUX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_100354442 2.459 ENST00000475887.1
GPR128
G protein-coupled receptor 128
chr7_-_23510086 2.151 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr2_-_216257849 2.011 ENST00000456923.1
FN1
fibronectin 1
chr1_-_109618566 1.854 ENST00000338366.5
TAF13
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr19_-_22379753 1.624 ENST00000397121.2
ZNF676
zinc finger protein 676
chr9_+_105757590 1.390 ENST00000374798.3
ENST00000487798.1
CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chr9_+_35673853 1.326 ENST00000378357.4
CA9
carbonic anhydrase IX
chrX_+_55246818 1.321 ENST00000374952.1
PAGE5
P antigen family, member 5 (prostate associated)
chr22_+_38071615 1.310 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr4_+_69681710 1.210 ENST00000265403.7
ENST00000458688.2
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr6_+_151561085 1.203 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr16_+_30064411 1.195 ENST00000338110.5
ALDOA
aldolase A, fructose-bisphosphate
chr12_-_10978957 1.124 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr8_-_62559366 1.116 ENST00000522919.1
ASPH
aspartate beta-hydroxylase
chr17_+_7942335 1.097 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
ALOX15B


arachidonate 15-lipoxygenase, type B


chr8_-_91095099 1.089 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr4_+_69962185 1.083 ENST00000305231.7
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_+_69962212 1.067 ENST00000508661.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr16_+_30064444 1.028 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
ALDOA


aldolase A, fructose-bisphosphate


chr19_+_45409011 0.975 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE


apolipoprotein E


chr10_-_90751038 0.955 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2


actin, alpha 2, smooth muscle, aorta


chr10_+_6779326 0.894 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr8_+_54764346 0.891 ENST00000297313.3
ENST00000344277.6
RGS20

regulator of G-protein signaling 20

chr1_-_186649543 0.884 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_102456277 0.871 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_211342432 0.850 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr7_+_80231466 0.848 ENST00000309881.7
ENST00000534394.1
CD36

CD36 molecule (thrombospondin receptor)

chr17_-_53809473 0.829 ENST00000575734.1
TMEM100
transmembrane protein 100
chr2_-_192016316 0.815 ENST00000358470.4
ENST00000432798.1
ENST00000450994.1
STAT4


signal transducer and activator of transcription 4


chr13_-_46679185 0.811 ENST00000439329.3
CPB2
carboxypeptidase B2 (plasma)
chr17_-_39526052 0.797 ENST00000251646.3
KRT33B
keratin 33B
chr1_+_8378140 0.773 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr9_+_125133315 0.762 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr10_-_73975657 0.761 ENST00000394919.1
ENST00000526751.1
ASCC1

activating signal cointegrator 1 complex subunit 1

chr19_-_4535233 0.754 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5


perilipin 5


chr10_-_121296045 0.751 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr19_-_19729725 0.751 ENST00000251203.9
PBX4
pre-B-cell leukemia homeobox 4
chr2_+_95691445 0.729 ENST00000353004.3
ENST00000354078.3
ENST00000349807.3
MAL


mal, T-cell differentiation protein


chr2_+_95691417 0.729 ENST00000309988.4
MAL
mal, T-cell differentiation protein
chr6_-_27880174 0.716 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr17_+_56315936 0.708 ENST00000543544.1
LPO
lactoperoxidase
chr19_+_41882466 0.705 ENST00000436170.2
TMEM91
transmembrane protein 91
chr19_+_46003056 0.704 ENST00000401593.1
ENST00000396736.2
PPM1N

protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)

chr4_-_90756769 0.695 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr6_+_121756809 0.693 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr12_+_31226779 0.685 ENST00000542838.1
ENST00000407793.2
ENST00000251758.5
ENST00000228264.6
ENST00000438391.2
ENST00000415475.2
ENST00000545668.1
ENST00000350437.4
DDX11







DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11







chr11_+_57365150 0.684 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1




serpin peptidase inhibitor, clade G (C1 inhibitor), member 1




chr19_+_48216600 0.681 ENST00000263277.3
ENST00000538399.1
EHD2

EH-domain containing 2

chr13_-_46679144 0.676 ENST00000181383.4
CPB2
carboxypeptidase B2 (plasma)
chr4_+_71200681 0.674 ENST00000273936.5
CABS1
calcium-binding protein, spermatid-specific 1
chr3_+_130650738 0.673 ENST00000504612.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr1_-_151804314 0.663 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr19_+_15052301 0.661 ENST00000248072.3
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chr5_-_146302078 0.654 ENST00000508545.2
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr1_-_54303949 0.644 ENST00000234725.8
NDC1
NDC1 transmembrane nucleoporin
chr1_-_54303934 0.644 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr6_-_131321863 0.637 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr3_+_8543393 0.631 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1


LIM and cysteine-rich domains 1


chr22_+_45148432 0.628 ENST00000389774.2
ENST00000396119.2
ENST00000336963.4
ENST00000356099.6
ENST00000412433.1
ARHGAP8




Rho GTPase activating protein 8




chr4_+_74275057 0.626 ENST00000511370.1
ALB
albumin
chr19_+_7011509 0.602 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr20_+_62492566 0.601 ENST00000369916.3
ABHD16B
abhydrolase domain containing 16B
chr13_-_46756351 0.598 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_64784471 0.593 ENST00000333722.5
C12orf56
chromosome 12 open reading frame 56
chr2_-_228497888 0.593 ENST00000264387.4
ENST00000409066.1
C2orf83

chromosome 2 open reading frame 83

chr2_-_187713891 0.590 ENST00000295131.2
ZSWIM2
zinc finger, SWIM-type containing 2
chr11_+_35201826 0.579 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr1_+_13910479 0.576 ENST00000509009.1
PDPN
podoplanin
chr15_+_40674963 0.571 ENST00000448395.2
KNSTRN
kinetochore-localized astrin/SPAG5 binding protein
chr15_+_40674920 0.562 ENST00000416151.2
ENST00000249776.8
KNSTRN

kinetochore-localized astrin/SPAG5 binding protein

chrX_-_107682702 0.561 ENST00000372216.4
COL4A6
collagen, type IV, alpha 6
chr19_+_41882598 0.556 ENST00000447302.2
ENST00000544232.1
ENST00000542945.1
ENST00000540732.1
TMEM91


CTC-435M10.3
transmembrane protein 91


2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein
chr4_+_70796784 0.555 ENST00000246891.4
ENST00000444405.3
CSN1S1

casein alpha s1

chr4_+_109571740 0.541 ENST00000361564.4
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr19_-_7040190 0.537 ENST00000381394.4
MBD3L4
methyl-CpG binding domain protein 3-like 4
chr19_-_58864848 0.537 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr19_+_7030589 0.536 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr11_-_89653576 0.533 ENST00000420869.1
TRIM49D1
tripartite motif containing 49D1
chr4_-_100575781 0.532 ENST00000511828.1
RP11-766F14.2
Protein LOC285556
chr14_-_64194745 0.525 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr1_-_151804222 0.520 ENST00000392697.3
RORC
RAR-related orphan receptor C
chr12_-_89413456 0.511 ENST00000500381.2
RP11-13A1.1
RP11-13A1.1
chr6_+_26273144 0.505 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr11_+_44117099 0.503 ENST00000533608.1
EXT2
exostosin glycosyltransferase 2
chr1_-_146068184 0.502 ENST00000604894.1
ENST00000369323.3
ENST00000479926.2
NBPF11


neuroblastoma breakpoint family, member 11


chr2_+_102953608 0.501 ENST00000311734.2
ENST00000409584.1
IL1RL1

interleukin 1 receptor-like 1

chr3_+_26735991 0.500 ENST00000456208.2
LRRC3B
leucine rich repeat containing 3B
chr12_+_15475331 0.498 ENST00000281171.4
PTPRO
protein tyrosine phosphatase, receptor type, O
chr4_-_159956333 0.498 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr3_-_172859017 0.496 ENST00000351008.3
SPATA16
spermatogenesis associated 16
chr11_+_5410607 0.488 ENST00000328611.3
OR51M1
olfactory receptor, family 51, subfamily M, member 1
chr22_-_29949680 0.488 ENST00000397873.2
ENST00000490103.1
THOC5

THO complex 5

chr5_+_60933634 0.487 ENST00000505642.1
C5orf64
chromosome 5 open reading frame 64
chr1_+_16083154 0.483 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr19_-_49243845 0.480 ENST00000222145.4
RASIP1
Ras interacting protein 1
chr12_+_21168630 0.480 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr6_-_131277510 0.478 ENST00000525193.1
ENST00000527659.1
EPB41L2

erythrocyte membrane protein band 4.1-like 2

chr3_+_44916098 0.477 ENST00000296125.4
TGM4
transglutaminase 4
chr5_-_16742330 0.476 ENST00000505695.1
ENST00000427430.2
MYO10

myosin X

chr7_-_36764142 0.476 ENST00000258749.5
ENST00000535891.1
AOAH

acyloxyacyl hydrolase (neutrophil)

chr1_+_57320437 0.473 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr2_+_102413726 0.469 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr19_-_52674896 0.467 ENST00000322146.8
ENST00000597065.1
ZNF836

zinc finger protein 836

chr5_+_173472607 0.464 ENST00000303177.3
ENST00000519867.1
NSG2

Neuron-specific protein family member 2

chr11_+_44117260 0.464 ENST00000358681.4
EXT2
exostosin glycosyltransferase 2
chrX_+_85969626 0.464 ENST00000484479.1
DACH2
dachshund homolog 2 (Drosophila)
chr2_-_214016314 0.461 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr5_+_162887556 0.458 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR


hyaluronan-mediated motility receptor (RHAMM)


chr6_-_27114577 0.455 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr12_-_58212487 0.453 ENST00000549994.1
AVIL
advillin
chr4_+_70916119 0.447 ENST00000246896.3
ENST00000511674.1
HTN1

histatin 1

chr16_+_16326352 0.446 ENST00000399336.4
ENST00000263012.6
ENST00000538468.1
NOMO3


NODAL modulator 3


chr1_+_115572415 0.445 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr5_-_11589131 0.436 ENST00000511377.1
CTNND2
catenin (cadherin-associated protein), delta 2
chr6_+_31105426 0.431 ENST00000547221.1
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr14_-_81425828 0.431 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128


centrosomal protein 128kDa


chr2_+_211421262 0.430 ENST00000233072.5
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr12_+_43086018 0.429 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr16_-_18573396 0.427 ENST00000543392.1
ENST00000381474.3
ENST00000330537.6
NOMO2


NODAL modulator 2


chr11_+_55578854 0.426 ENST00000333973.2
OR5L1
olfactory receptor, family 5, subfamily L, member 1
chr20_-_43150601 0.423 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
SERINC3


serine incorporator 3


chr22_+_24198890 0.423 ENST00000345044.6
SLC2A11
solute carrier family 2 (facilitated glucose transporter), member 11
chr5_-_11588907 0.420 ENST00000513598.1
ENST00000503622.1
CTNND2

catenin (cadherin-associated protein), delta 2

chr6_+_106534192 0.419 ENST00000369091.2
ENST00000369096.4
PRDM1

PR domain containing 1, with ZNF domain

chr22_-_50523760 0.418 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr1_-_13052998 0.418 ENST00000436041.1
WI2-3308P17.2
Uncharacterized protein
chr7_-_92777606 0.415 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr5_-_156390230 0.412 ENST00000407087.3
ENST00000274532.2
TIMD4

T-cell immunoglobulin and mucin domain containing 4

chr12_+_20968608 0.411 ENST00000553473.1
ENST00000554957.1
ENST00000381541.3
ENST00000540229.1
SLCO1B3
SLCO1B7
LST3

solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein

chr4_+_187187098 0.409 ENST00000403665.2
ENST00000264692.4
F11

coagulation factor XI

chr1_+_155179012 0.407 ENST00000609421.1
MTX1
metaxin 1
chrX_-_47489244 0.405 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP


complement factor properdin


chr1_+_13910194 0.402 ENST00000376057.4
ENST00000510906.1
PDPN

podoplanin

chr2_+_90077680 0.399 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr16_-_69788816 0.396 ENST00000268802.5
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr2_+_120687335 0.395 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr1_-_54304212 0.394 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr1_+_73771844 0.392 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1



RP4-598G3.1



chr1_-_147610081 0.392 ENST00000369226.3
NBPF24
neuroblastoma breakpoint family, member 24
chr12_+_26348429 0.391 ENST00000242729.2
SSPN
sarcospan
chr3_+_35683651 0.390 ENST00000187397.4
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_-_110933611 0.389 ENST00000472422.2
ENST00000437429.2
SLC16A4

solute carrier family 16, member 4

chr1_-_100231349 0.388 ENST00000287474.5
ENST00000414213.1
FRRS1

ferric-chelate reductase 1

chr1_-_76398077 0.386 ENST00000284142.6
ASB17
ankyrin repeat and SOCS box containing 17
chr4_-_70826725 0.385 ENST00000353151.3
CSN2
casein beta
chr8_-_124037890 0.382 ENST00000519018.1
ENST00000523036.1
DERL1

derlin 1

chr3_+_122785895 0.381 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr3_+_157827841 0.381 ENST00000295930.3
ENST00000471994.1
ENST00000464171.1
ENST00000312179.6
ENST00000475278.2
RSRC1




arginine/serine-rich coiled-coil 1




chr4_+_71587669 0.378 ENST00000381006.3
ENST00000226328.4
RUFY3

RUN and FYVE domain containing 3

chr3_+_136676851 0.377 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr4_-_143227088 0.373 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chrX_+_54947229 0.372 ENST00000442098.1
ENST00000430420.1
ENST00000453081.1
ENST00000173898.7
ENST00000319167.8
ENST00000375022.4
ENST00000399736.1
ENST00000440072.1
ENST00000420798.2
ENST00000431115.1
ENST00000440759.1
ENST00000375041.2
TRO











trophinin











chr21_+_43619796 0.372 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr9_-_21187598 0.371 ENST00000421715.1
IFNA4
interferon, alpha 4
chr16_+_446713 0.367 ENST00000397722.1
ENST00000454619.1
NME4

NME/NM23 nucleoside diphosphate kinase 4

chr8_+_71485681 0.367 ENST00000391684.1
AC120194.1
AC120194.1
chr1_-_110933663 0.367 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4


solute carrier family 16, member 4


chr11_+_62623544 0.365 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
SLC3A2


solute carrier family 3 (amino acid transporter heavy chain), member 2


chr17_-_64216748 0.365 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr5_-_180665195 0.364 ENST00000509148.1
GNB2L1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr3_-_165555200 0.364 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE



butyrylcholinesterase



chr5_-_115910630 0.359 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr11_+_55944094 0.359 ENST00000312298.1
OR5J2
olfactory receptor, family 5, subfamily J, member 2
chr10_+_70980051 0.357 ENST00000354624.5
ENST00000395086.2
HKDC1

hexokinase domain containing 1

chr1_+_45265897 0.355 ENST00000372201.4
PLK3
polo-like kinase 3
chr2_-_89442621 0.354 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr18_+_61445007 0.354 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr6_+_73076432 0.352 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr3_+_136676707 0.352 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr4_-_34041504 0.351 ENST00000512581.1
ENST00000505018.1
RP11-79E3.3

RP11-79E3.3

chr4_+_15341442 0.350 ENST00000397700.2
ENST00000295297.4
C1QTNF7

C1q and tumor necrosis factor related protein 7

chr3_+_35721182 0.349 ENST00000413378.1
ENST00000417925.1
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr1_-_166028709 0.344 ENST00000595430.1
AL626787.1
AL626787.1
chr1_+_144146808 0.344 ENST00000369190.5
ENST00000412624.2
ENST00000369365.3
NBPF8


neuroblastoma breakpoint family, member 8


chr12_+_26348246 0.342 ENST00000422622.2
SSPN
sarcospan
chr12_-_10605929 0.342 ENST00000347831.5
ENST00000359151.3
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr13_+_23755054 0.339 ENST00000218867.3
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr1_+_145293371 0.332 ENST00000342960.5
NBPF10
neuroblastoma breakpoint family, member 10
chr1_+_87458692 0.329 ENST00000356813.4
ENST00000370548.2
HS2ST1
RP5-1052I5.2
heparan sulfate 2-O-sulfotransferase 1
Heparan sulfate 2-O-sulfotransferase 1
chr8_-_110986918 0.329 ENST00000297404.1
KCNV1
potassium channel, subfamily V, member 1
chr5_+_180794269 0.326 ENST00000456475.1
OR4F3
olfactory receptor, family 4, subfamily F, member 3
chr4_-_110624564 0.326 ENST00000352981.3
ENST00000265164.2
ENST00000505486.1
CASP6


caspase 6, apoptosis-related cysteine peptidase


chr12_-_51718436 0.324 ENST00000544402.1
BIN2
bridging integrator 2
chr1_-_85097431 0.323 ENST00000327308.3
C1orf180
chromosome 1 open reading frame 180
chr2_+_89986318 0.322 ENST00000491977.1
IGKV2D-29
immunoglobulin kappa variable 2D-29
chr2_+_48796120 0.321 ENST00000394754.1
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chrX_+_55246771 0.321 ENST00000289619.5
ENST00000374955.3
PAGE5

P antigen family, member 5 (prostate associated)

chr12_+_100041527 0.320 ENST00000324341.1
FAM71C
family with sequence similarity 71, member C
chr8_+_77593448 0.317 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr4_+_90800656 0.315 ENST00000394980.1
MMRN1
multimerin 1
chr10_+_5238793 0.314 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr7_+_93535866 0.314 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1


chr4_-_70080449 0.313 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr12_-_11422630 0.312 ENST00000381842.3
ENST00000538488.1
PRB3

proline-rich protein BstNI subfamily 3

chr3_+_35682913 0.312 ENST00000449196.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr12_-_122879969 0.308 ENST00000540304.1
CLIP1
CAP-GLY domain containing linker protein 1
chr15_-_59981479 0.307 ENST00000607373.1
BNIP2
BCL2/adenovirus E1B 19kDa interacting protein 2
chr6_-_30658745 0.304 ENST00000376420.5
ENST00000376421.5
NRM

nurim (nuclear envelope membrane protein)

chr18_+_61254534 0.303 ENST00000269489.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr18_-_70532906 0.303 ENST00000299430.2
ENST00000397929.1
NETO1

neuropilin (NRP) and tolloid (TLL)-like 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.6 1.7 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.4 0.4 GO:1903487 regulation of lactation(GO:1903487)
0.4 1.5 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.3 1.0 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.3 1.0 GO:2000646 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.3 1.3 GO:0071400 cellular response to oleic acid(GO:0071400)
0.3 1.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.3 1.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 1.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 0.8 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.2 0.7 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.2 0.6 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.2 0.7 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.2 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 1.0 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.6 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.6 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.7 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.7 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.1 0.5 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.4 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.1 2.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.4 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.8 GO:2000334 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 1.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.4 GO:0007113 endomitotic cell cycle(GO:0007113) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.1 0.7 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 1.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.8 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.3 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.1 0.4 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.2 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 1.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:1902725 trans-synaptic signaling by trans-synaptic complex(GO:0099545) negative regulation of satellite cell differentiation(GO:1902725)
0.1 1.1 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.7 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 0.4 GO:0060356 leucine import(GO:0060356)
0.1 0.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.6 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.5 GO:0009597 detection of virus(GO:0009597)
0.1 1.6 GO:0036315 cellular response to sterol(GO:0036315)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 1.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.1 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1 0.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.4 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1 0.3 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 2.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.3 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.2 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 0.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.3 GO:1990523 bone regeneration(GO:1990523)
0.1 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 1.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 1.0 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 1.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 4.0 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.3 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 1.0 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.2 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.1 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 1.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.6 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.6 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) regulation of AV node cell action potential(GO:0098904) regulation of SA node cell action potential(GO:0098907)
0.0 0.4 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 1.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.4 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 2.1 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 1.7 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.4 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.4 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.2 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0033005 positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 1.0 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.4 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0032106 positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0 0.2 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.8 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.4 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.5 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.6 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916) forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0032930 positive regulation of superoxide anion generation(GO:0032930)
0.0 0.5 GO:0051693 actin filament capping(GO:0051693)
0.0 0.3 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.8 GO:0046847 filopodium assembly(GO:0046847)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.5 1.4 GO:0033150 cytoskeletal calyx(GO:0033150)
0.3 1.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 2.2 GO:0005577 fibrinogen complex(GO:0005577)
0.2 1.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 1.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.0 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.4 GO:0071749 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.1 0.4 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 1.1 GO:0008091 spectrin(GO:0008091)
0.1 0.3 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.7 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.7 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0097679 other organism cytoplasm(GO:0097679)
0.0 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 4.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 2.0 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.7 GO:0031514 motile cilium(GO:0031514)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 1.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.5 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.7 GO:0016020 membrane(GO:0016020)
0.0 1.8 GO:0005901 caveola(GO:0005901)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 1.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.9 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0005840 ribosome(GO:0005840)
0.0 0.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4 1.3 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.4 1.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.4 1.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.3 1.3 GO:0030395 lactose binding(GO:0030395)
0.2 1.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 1.0 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 1.1 GO:0005499 vitamin D binding(GO:0005499)
0.2 2.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.6 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 1.3 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.5 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 0.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.8 GO:0035473 lipase binding(GO:0035473)
0.1 0.4 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.7 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.1 GO:0042731 PH domain binding(GO:0042731)
0.1 0.7 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.5 GO:0033265 choline binding(GO:0033265)
0.1 0.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 1.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 1.0 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 1.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.1 1.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 2.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 2.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.0 GO:0005549 odorant binding(GO:0005549)
0.1 0.4 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 1.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 0.2 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 1.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.8 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.4 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 3.0 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 2.0 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.5 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0001848 complement binding(GO:0001848)
0.0 0.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 1.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.5 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.9 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 3.2 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.5 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 1.5 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 1.0 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.8 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 0.9 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.6 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 1.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID_IGF1_PATHWAY IGF1 pathway
0.0 0.6 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.7 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.1 PID_MET_PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.1 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.4 PID_PDGFRB_PATHWAY PDGFR-beta signaling pathway
0.0 0.7 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.4 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.5 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.3 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.9 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.1 REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.1 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.1 1.0 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 4.5 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.2 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.3 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 1.0 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.7 REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.6 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 2.4 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.6 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.9 REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.0 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 2.6 REACTOME_DIABETES_PATHWAYS Genes involved in Diabetes pathways
0.0 0.1 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.2 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor