Motif ID: CUX2
Z-value: 1.104

Transcription factors associated with CUX2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
CUX2 | ENSG00000111249.9 | CUX2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
CUX2 | hg19_v2_chr12_+_111471828_111471975 | 0.02 | 9.2e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 175 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 4.0 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
0.1 | 2.4 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
0.1 | 2.2 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
0.0 | 2.1 | GO:0042035 | regulation of cytokine biosynthetic process(GO:0042035) |
0.7 | 2.0 | GO:0052047 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) |
0.6 | 1.7 | GO:0071790 | spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790) |
0.0 | 1.7 | GO:0009301 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
0.1 | 1.6 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
0.1 | 1.6 | GO:0036315 | cellular response to sterol(GO:0036315) |
0.4 | 1.5 | GO:0003331 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
0.3 | 1.3 | GO:0071400 | cellular response to oleic acid(GO:0071400) |
0.3 | 1.3 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
0.3 | 1.3 | GO:0002317 | plasma cell differentiation(GO:0002317) |
0.0 | 1.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
0.3 | 1.2 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
0.1 | 1.2 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.0 | 1.2 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.2 | 1.1 | GO:0051122 | hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122) |
0.1 | 1.1 | GO:0035502 | metanephric part of ureteric bud development(GO:0035502) |
0.1 | 1.1 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 61 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 4.4 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
0.2 | 2.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
0.0 | 2.0 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
0.0 | 1.8 | GO:0005901 | caveola(GO:0005901) |
0.6 | 1.7 | GO:0070762 | nuclear pore transmembrane ring(GO:0070762) |
0.0 | 1.5 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.5 | 1.4 | GO:0033150 | cytoskeletal calyx(GO:0033150) |
0.0 | 1.4 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.2 | 1.3 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
0.0 | 1.3 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 1.3 | GO:0043195 | terminal bouton(GO:0043195) |
0.1 | 1.1 | GO:0008091 | spectrin(GO:0008091) |
0.0 | 1.1 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.3 | 1.0 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
0.2 | 1.0 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.1 | 1.0 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
0.1 | 1.0 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
0.0 | 0.9 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.9 | GO:0043679 | axon terminus(GO:0043679) |
0.0 | 0.8 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 113 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 3.0 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.1 | 2.6 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
0.1 | 2.5 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.2 | 2.2 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.0 | 2.0 | GO:0016504 | peptidase activator activity(GO:0016504) |
0.4 | 1.7 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
0.1 | 1.7 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.1 | 1.5 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.1 | 1.4 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
0.4 | 1.3 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
0.4 | 1.3 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
0.3 | 1.3 | GO:0030395 | lactose binding(GO:0030395) |
0.2 | 1.3 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.1 | 1.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.1 | 1.2 | GO:0008142 | oxysterol binding(GO:0008142) |
0.1 | 1.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.0 | 1.2 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 1.2 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.4 | 1.1 | GO:0016165 | linoleate 13S-lipoxygenase activity(GO:0016165) |
0.2 | 1.1 | GO:0005499 | vitamin D binding(GO:0005499) |
Gene overrepresentation in C2:CP category:
Showing 1 to 20 of 22 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 3.2 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.1 | 2.0 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.0 | 1.5 | PID_EPHB_FWD_PATHWAY | EPHB forward signaling |
0.0 | 1.5 | PID_RAS_PATHWAY | Regulation of Ras family activation |
0.0 | 1.4 | PID_PDGFRB_PATHWAY | PDGFR-beta signaling pathway |
0.0 | 1.0 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
0.0 | 1.0 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 0.9 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.0 | 0.9 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
0.0 | 0.8 | PID_IL27_PATHWAY | IL27-mediated signaling events |
0.0 | 0.8 | PID_INTEGRIN3_PATHWAY | Beta3 integrin cell surface interactions |
0.0 | 0.7 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
0.0 | 0.7 | PID_ALPHA_SYNUCLEIN_PATHWAY | Alpha-synuclein signaling |
0.0 | 0.6 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.0 | 0.6 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.0 | 0.6 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
0.0 | 0.5 | PID_S1P_META_PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
0.0 | 0.5 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | PI3K Pathway |
0.0 | 0.4 | PID_IGF1_PATHWAY | IGF1 pathway |
0.0 | 0.4 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
Gene overrepresentation in C2:CP:REACTOME category:
Showing 1 to 20 of 34 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 4.5 | REACTOME_OLFACTORY_SIGNALING_PATHWAY | Genes involved in Olfactory Signaling Pathway |
0.0 | 2.6 | REACTOME_DIABETES_PATHWAYS | Genes involved in Diabetes pathways |
0.1 | 2.5 | REACTOME_GLUCURONIDATION | Genes involved in Glucuronidation |
0.0 | 2.4 | REACTOME_AMYLOIDS | Genes involved in Amyloids |
0.0 | 2.2 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
0.1 | 2.1 | REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTERGRINS_ | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
0.1 | 1.9 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.0 | 1.7 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
0.1 | 1.3 | REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
0.0 | 1.3 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
0.0 | 1.3 | REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
0.0 | 1.2 | REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
0.0 | 1.2 | REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ | Genes involved in Response to elevated platelet cytosolic Ca2+ |
0.1 | 1.1 | REACTOME_INTRINSIC_PATHWAY | Genes involved in Intrinsic Pathway |
0.1 | 1.0 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.0 | 1.0 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.0 | 1.0 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.9 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | Genes involved in G alpha (z) signalling events |
0.0 | 0.7 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.0 | 0.6 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |