Motif ID: CUUUGGU

Z-value: 0.604


Mature miRNA associated with seed CUUUGGU:

NamemiRBase Accession
hsa-miR-9-5p MIMAT0000441



Activity profile for motif CUUUGGU.

activity profile for motif CUUUGGU


Sorted Z-values histogram for motif CUUUGGU

Sorted Z-values for motif CUUUGGU



Network of associatons between targets according to the STRING database.



First level regulatory network of CUUUGGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_41742697 1.457 ENST00000242208.4
INHBA
inhibin, beta A
chr2_-_1748214 1.282 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN


peroxidasin homolog (Drosophila)


chr11_+_69924397 1.114 ENST00000355303.5
ANO1
anoctamin 1, calcium activated chloride channel
chr21_-_44846999 0.951 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr12_+_66217911 0.920 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr10_+_99400443 0.911 ENST00000370631.3
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
chr5_-_127873659 0.888 ENST00000262464.4
FBN2
fibrillin 2
chr2_-_208030647 0.882 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr3_-_74570291 0.860 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr2_-_235405679 0.810 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr7_-_23510086 0.777 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr17_-_41174424 0.755 ENST00000355653.3
VAT1
vesicle amine transport 1
chr2_+_48541776 0.736 ENST00000413569.1
ENST00000340553.3
FOXN2

forkhead box N2

chr9_-_123639600 0.689 ENST00000373896.3
PHF19
PHD finger protein 19
chr1_+_90098606 0.673 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr10_+_99344104 0.669 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr6_+_106546808 0.668 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr11_+_94501497 0.663 ENST00000317829.8
ENST00000317837.9
ENST00000433060.2
AMOTL1


angiomotin like 1


chr3_+_47324424 0.661 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr12_+_27485823 0.639 ENST00000395901.2
ENST00000546179.1
ARNTL2

aryl hydrocarbon receptor nuclear translocator-like 2

chr1_-_154943212 0.637 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr15_-_42264702 0.635 ENST00000220325.4
EHD4
EH-domain containing 4
chr3_-_98620500 0.630 ENST00000326840.6
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr10_-_33623564 0.618 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr18_-_21242833 0.608 ENST00000586087.1
ENST00000592179.1
ANKRD29

ankyrin repeat domain 29

chr13_+_110959598 0.604 ENST00000360467.5
COL4A2
collagen, type IV, alpha 2
chr1_+_37940153 0.592 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr2_+_64681219 0.573 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr1_-_179198702 0.565 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr1_-_6453399 0.554 ENST00000608083.1
ACOT7
acyl-CoA thioesterase 7
chr15_-_41624685 0.523 ENST00000560640.1
ENST00000220514.3
OIP5

Opa interacting protein 5

chr15_-_56209306 0.514 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4


neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase


chr15_+_74833518 0.507 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr5_+_135364584 0.501 ENST00000442011.2
ENST00000305126.8
TGFBI

transforming growth factor, beta-induced, 68kDa

chr8_+_22224811 0.498 ENST00000381237.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr2_-_102003987 0.492 ENST00000324768.5
CREG2
cellular repressor of E1A-stimulated genes 2
chr1_-_208417620 0.482 ENST00000367033.3
PLXNA2
plexin A2
chr9_+_131102925 0.481 ENST00000372870.1
ENST00000300456.4
SLC27A4

solute carrier family 27 (fatty acid transporter), member 4

chr13_+_32605437 0.480 ENST00000380250.3
FRY
furry homolog (Drosophila)
chr17_+_1958388 0.471 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chr12_+_56521840 0.471 ENST00000394048.5
ESYT1
extended synaptotagmin-like protein 1
chr9_-_72287191 0.465 ENST00000265381.4
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr2_+_75061108 0.458 ENST00000290573.2
HK2
hexokinase 2
chrX_-_46618490 0.436 ENST00000328306.4
SLC9A7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr3_+_150126101 0.433 ENST00000361875.3
ENST00000361136.2
TSC22D2

TSC22 domain family, member 2

chr4_-_82136114 0.433 ENST00000395578.1
ENST00000418486.2
PRKG2

protein kinase, cGMP-dependent, type II

chrX_-_109561294 0.431 ENST00000372059.2
ENST00000262844.5
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr1_-_6321035 0.428 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr1_-_27816556 0.428 ENST00000536657.1
WASF2
WAS protein family, member 2
chr7_-_98741642 0.425 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr19_+_1941117 0.423 ENST00000255641.8
CSNK1G2
casein kinase 1, gamma 2
chr4_+_17812525 0.421 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr20_+_35974532 0.409 ENST00000373578.2
SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr1_+_107683644 0.408 ENST00000370067.1
NTNG1
netrin G1
chr22_-_36784035 0.408 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chr9_-_35732362 0.405 ENST00000314888.9
ENST00000540444.1
TLN1

talin 1

chr10_-_15210666 0.399 ENST00000378165.4
NMT2
N-myristoyltransferase 2
chr17_-_1395954 0.398 ENST00000359786.5
MYO1C
myosin IC
chr13_-_23949671 0.398 ENST00000402364.1
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr6_+_31126291 0.396 ENST00000376257.3
ENST00000376255.4
TCF19

transcription factor 19

chr6_-_42419649 0.382 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1


transcriptional regulating factor 1


chr9_+_137218362 0.378 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr22_+_38302285 0.374 ENST00000215957.6
MICALL1
MICAL-like 1
chr5_-_131563501 0.369 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2




prolyl 4-hydroxylase, alpha polypeptide II




chr6_+_116601265 0.366 ENST00000452085.3
DSE
dermatan sulfate epimerase
chr7_-_25019760 0.364 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
OSBPL3



oxysterol binding protein-like 3



chr6_+_151186554 0.364 ENST00000367321.3
ENST00000367307.4
MTHFD1L

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

chr3_+_101504200 0.364 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr8_-_28243934 0.354 ENST00000521185.1
ENST00000520290.1
ENST00000344423.5
ZNF395


zinc finger protein 395


chr20_-_36793774 0.353 ENST00000361475.2
TGM2
transglutaminase 2
chr1_-_241803649 0.352 ENST00000366554.2
OPN3
opsin 3
chr1_+_25071848 0.351 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr19_+_39616410 0.351 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4






p21 protein (Cdc42/Rac)-activated kinase 4






chr1_-_155942086 0.351 ENST00000368315.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr11_+_122526383 0.344 ENST00000284273.5
UBASH3B
ubiquitin associated and SH3 domain containing B
chr12_-_113909877 0.341 ENST00000261731.3
LHX5
LIM homeobox 5
chr11_+_60681346 0.338 ENST00000227525.3
TMEM109
transmembrane protein 109
chr19_-_14629224 0.336 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr10_+_102756800 0.333 ENST00000370223.3
LZTS2
leucine zipper, putative tumor suppressor 2
chr11_-_128392085 0.333 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1




v-ets avian erythroblastosis virus E26 oncogene homolog 1




chr17_+_73717516 0.328 ENST00000200181.3
ENST00000339591.3
ITGB4

integrin, beta 4

chr19_+_41222998 0.325 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr5_-_64064508 0.320 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr19_-_40324255 0.312 ENST00000593685.1
ENST00000600611.1
DYRK1B

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

chr9_-_115095883 0.308 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
PTBP3



polypyrimidine tract binding protein 3



chr11_+_119076745 0.307 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr3_+_171758344 0.305 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr14_-_77279153 0.304 ENST00000251089.2
ANGEL1
angel homolog 1 (Drosophila)
chr5_+_82767284 0.304 ENST00000265077.3
VCAN
versican
chr1_+_7831323 0.302 ENST00000054666.6
VAMP3
vesicle-associated membrane protein 3
chr15_+_81293254 0.298 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr1_-_76076793 0.298 ENST00000370859.3
SLC44A5
solute carrier family 44, member 5
chr8_+_42752053 0.296 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chr5_-_147162078 0.292 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr6_-_26285737 0.291 ENST00000377727.1
ENST00000289352.1
HIST1H4H

histone cluster 1, H4h

chr20_+_18568537 0.289 ENST00000377452.3
DTD1
D-tyrosyl-tRNA deacylase 1
chr10_+_101419187 0.288 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr19_+_7968728 0.286 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
MAP2K7



mitogen-activated protein kinase kinase 7



chr2_-_119605253 0.285 ENST00000295206.6
EN1
engrailed homeobox 1
chr1_+_50574585 0.285 ENST00000371824.1
ENST00000371823.4
ELAVL4

ELAV like neuron-specific RNA binding protein 4

chr16_-_79634595 0.284 ENST00000326043.4
ENST00000393350.1
MAF

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog

chr4_-_73434498 0.283 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr10_-_105110831 0.282 ENST00000337211.4
PCGF6
polycomb group ring finger 6
chr2_+_11674213 0.281 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr13_+_98086445 0.280 ENST00000245304.4
RAP2A
RAP2A, member of RAS oncogene family
chr6_+_160390102 0.277 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr5_-_76788317 0.276 ENST00000296679.4
WDR41
WD repeat domain 41
chr15_-_72612470 0.274 ENST00000287202.5
CELF6
CUGBP, Elav-like family member 6
chr8_-_134309335 0.274 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1









N-myc downstream regulated 1









chr15_+_91411810 0.271 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr21_-_15755446 0.271 ENST00000544452.1
ENST00000285667.3
HSPA13

heat shock protein 70kDa family, member 13

chr14_-_53258314 0.270 ENST00000216410.3
ENST00000557604.1
GNPNAT1

glucosamine-phosphate N-acetyltransferase 1

chr16_+_29823552 0.270 ENST00000300797.6
PRRT2
proline-rich transmembrane protein 2
chr1_-_26232951 0.268 ENST00000426559.2
ENST00000455785.2
STMN1

stathmin 1

chr5_+_34656331 0.263 ENST00000265109.3
RAI14
retinoic acid induced 14
chr1_+_154300217 0.258 ENST00000368489.3
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr16_+_8768422 0.258 ENST00000268251.8
ENST00000564714.1
ABAT

4-aminobutyrate aminotransferase

chr16_+_71392616 0.257 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
CALB2


calbindin 2


chrX_+_28605516 0.254 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr22_-_29949680 0.253 ENST00000397873.2
ENST00000490103.1
THOC5

THO complex 5

chr8_-_21999362 0.252 ENST00000334530.5
ENST00000518664.1
REEP4

receptor accessory protein 4

chr17_-_79139817 0.250 ENST00000326724.4
AATK
apoptosis-associated tyrosine kinase
chr3_-_120170052 0.250 ENST00000295633.3
FSTL1
follistatin-like 1
chr8_-_144897549 0.244 ENST00000356994.2
ENST00000320476.3
SCRIB

scribbled planar cell polarity protein

chr8_+_38088861 0.244 ENST00000397166.2
ENST00000533100.1
DDHD2

DDHD domain containing 2

chr11_-_13484713 0.242 ENST00000526841.1
ENST00000529708.1
ENST00000278174.5
ENST00000528120.1
BTBD10



BTB (POZ) domain containing 10



chr1_+_65613217 0.242 ENST00000545314.1
AK4
adenylate kinase 4
chr11_-_116968987 0.241 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3






SIK family kinase 3






chr5_-_140998616 0.240 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1





diaphanous-related formin 1





chr9_-_34589700 0.238 ENST00000351266.4
CNTFR
ciliary neurotrophic factor receptor
chr19_+_7895074 0.237 ENST00000270530.4
EVI5L
ecotropic viral integration site 5-like
chr15_+_40675132 0.236 ENST00000608100.1
ENST00000557920.1
KNSTRN

kinetochore-localized astrin/SPAG5 binding protein

chr1_+_93811438 0.235 ENST00000370272.4
ENST00000370267.1
DR1

down-regulator of transcription 1, TBP-binding (negative cofactor 2)

chr11_+_64126614 0.235 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4


ribosomal protein S6 kinase, 90kDa, polypeptide 4


chr2_-_130939115 0.235 ENST00000441135.1
ENST00000339679.7
ENST00000426662.2
ENST00000443958.2
ENST00000351288.6
ENST00000453750.1
ENST00000452225.2
SMPD4






sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)






chrX_+_41192595 0.235 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr16_-_85045131 0.234 ENST00000313732.4
ZDHHC7
zinc finger, DHHC-type containing 7
chr1_+_117452669 0.233 ENST00000393203.2
PTGFRN
prostaglandin F2 receptor inhibitor
chr20_-_14318248 0.233 ENST00000378053.3
ENST00000341420.4
FLRT3

fibronectin leucine rich transmembrane protein 3

chr7_+_28452130 0.231 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr9_+_112403088 0.230 ENST00000448454.2
PALM2
paralemmin 2
chr22_-_42017021 0.230 ENST00000263256.6
DESI1
desumoylating isopeptidase 1
chr13_-_33859819 0.229 ENST00000336934.5
STARD13
StAR-related lipid transfer (START) domain containing 13
chr17_-_49198216 0.229 ENST00000262013.7
ENST00000357122.4
SPAG9

sperm associated antigen 9

chr5_-_149535421 0.228 ENST00000261799.4
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr3_+_154797428 0.228 ENST00000460393.1
MME
membrane metallo-endopeptidase
chr4_+_87856129 0.226 ENST00000395146.4
ENST00000507468.1
AFF1

AF4/FMR2 family, member 1

chr9_+_116638562 0.224 ENST00000374126.5
ENST00000288466.7
ZNF618

zinc finger protein 618

chr3_-_119813264 0.222 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta
chr9_-_38069208 0.222 ENST00000377707.3
ENST00000377700.4
SHB

Src homology 2 domain containing adaptor protein B

chrX_+_16737718 0.222 ENST00000380155.3
SYAP1
synapse associated protein 1
chr17_-_41132410 0.222 ENST00000409399.1
ENST00000421990.2
ENST00000409446.3
ENST00000453594.1
PTGES3L-AARSD1

PTGES3L

PTGES3L-AARSD1 readthrough

prostaglandin E synthase 3 (cytosolic)-like

chr12_+_113796347 0.221 ENST00000545182.2
ENST00000280800.3
PLBD2

phospholipase B domain containing 2

chr2_+_171673072 0.221 ENST00000358196.3
ENST00000375272.1
GAD1

glutamate decarboxylase 1 (brain, 67kDa)

chr21_+_33245548 0.221 ENST00000270112.2
HUNK
hormonally up-regulated Neu-associated kinase
chr17_+_64298944 0.221 ENST00000413366.3
PRKCA
protein kinase C, alpha
chr21_+_35445827 0.220 ENST00000381151.3
ENST00000608209.1
SLC5A3
SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
sodium/myo-inositol cotransporter
chr6_+_114178512 0.218 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr5_+_170814803 0.218 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
NPM1



nucleophosmin (nucleolar phosphoprotein B23, numatrin)



chrX_+_9754461 0.215 ENST00000380913.3
SHROOM2
shroom family member 2
chr9_-_123555655 0.212 ENST00000340778.5
ENST00000453291.1
ENST00000608872.1
FBXW2


F-box and WD repeat domain containing 2


chr14_+_103058948 0.211 ENST00000262241.6
RCOR1
REST corepressor 1
chr22_-_18507279 0.209 ENST00000441493.2
ENST00000444520.1
ENST00000207726.7
ENST00000429452.1
MICAL3



microtubule associated monooxygenase, calponin and LIM domain containing 3



chrX_+_46696372 0.209 ENST00000218340.3
RP2
retinitis pigmentosa 2 (X-linked recessive)
chr3_-_123603137 0.208 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK



myosin light chain kinase



chr17_-_62658186 0.207 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr22_-_36236265 0.206 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2




RNA binding protein, fox-1 homolog (C. elegans) 2




chr6_-_48036363 0.206 ENST00000543600.1
ENST00000398738.2
ENST00000339488.4
PTCHD4


patched domain containing 4


chr15_-_48937982 0.202 ENST00000316623.5
FBN1
fibrillin 1
chr9_+_116917807 0.201 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr1_-_85156216 0.200 ENST00000342203.3
ENST00000370612.4
SSX2IP

synovial sarcoma, X breakpoint 2 interacting protein

chr9_+_77112244 0.199 ENST00000376896.3
RORB
RAR-related orphan receptor B
chr3_+_111578027 0.198 ENST00000431670.2
ENST00000412622.1
PHLDB2

pleckstrin homology-like domain, family B, member 2

chr1_+_154377669 0.198 ENST00000368485.3
ENST00000344086.4
IL6R

interleukin 6 receptor

chr8_+_1449532 0.195 ENST00000421627.2
DLGAP2
discs, large (Drosophila) homolog-associated protein 2
chr14_+_52118576 0.195 ENST00000395718.2
ENST00000344768.5
FRMD6

FERM domain containing 6

chr19_+_1752372 0.192 ENST00000382349.4
ONECUT3
one cut homeobox 3
chr9_+_95858485 0.192 ENST00000375464.2
C9orf89
chromosome 9 open reading frame 89
chr22_+_50354104 0.191 ENST00000360612.4
PIM3
pim-3 oncogene
chr13_-_40177261 0.191 ENST00000379589.3
LHFP
lipoma HMGIC fusion partner
chr7_+_44084262 0.190 ENST00000456905.1
ENST00000440166.1
ENST00000452943.1
ENST00000468694.1
ENST00000494774.1
ENST00000490734.2
DBNL





drebrin-like





chr20_+_46130601 0.190 ENST00000341724.6
NCOA3
nuclear receptor coactivator 3
chr1_-_165325939 0.190 ENST00000342310.3
LMX1A
LIM homeobox transcription factor 1, alpha
chr17_-_42908155 0.188 ENST00000426548.1
ENST00000590758.1
ENST00000591424.1
GJC1


gap junction protein, gamma 1, 45kDa


chr19_-_15560730 0.187 ENST00000389282.4
ENST00000263381.7
WIZ

widely interspaced zinc finger motifs

chr3_-_185542817 0.187 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr14_+_50359773 0.187 ENST00000298316.5
ARF6
ADP-ribosylation factor 6
chr14_-_34931458 0.186 ENST00000298130.4
SPTSSA
serine palmitoyltransferase, small subunit A
chr3_-_138553594 0.185 ENST00000477593.1
ENST00000483968.1
PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

chr2_+_228336849 0.185 ENST00000409979.2
ENST00000310078.8
AGFG1

ArfGAP with FG repeats 1

chrX_-_131352152 0.185 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr5_-_77590480 0.183 ENST00000519295.1
ENST00000255194.6
AP3B1

adaptor-related protein complex 3, beta 1 subunit

chr13_-_77460525 0.183 ENST00000377474.2
ENST00000317765.2
KCTD12

potassium channel tetramerization domain containing 12

chr11_+_118477144 0.181 ENST00000361417.2
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr11_+_35965531 0.179 ENST00000528989.1
ENST00000524419.1
ENST00000315571.5
LDLRAD3


low density lipoprotein receptor class A domain containing 3


chr14_+_53019822 0.177 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr1_+_6673745 0.176 ENST00000377648.4
PHF13
PHD finger protein 13
chr7_+_156931606 0.176 ENST00000348165.5
UBE3C
ubiquitin protein ligase E3C
chr18_+_67068228 0.175 ENST00000382713.5
DOK6
docking protein 6
chr5_-_16936340 0.174 ENST00000507288.1
ENST00000513610.1
MYO10

myosin X


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.4 1.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.3 0.3 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.2 0.9 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.2 0.6 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.2 1.0 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.4 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.4 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.6 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.7 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.4 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.4 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.1 0.8 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 1.1 GO:0015705 iodide transport(GO:0015705)
0.1 0.6 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.4 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.7 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 1.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.4 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.4 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.3 GO:0060978 angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.1 0.5 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.2 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.3 GO:0061743 motor learning(GO:0061743)
0.1 0.4 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.5 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.4 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1 0.6 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.3 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.5 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.5 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 0.7 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.2 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 0.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.2 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.1 0.3 GO:0051136 regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.2 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878) copper ion transmembrane transport(GO:0035434)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.2 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.5 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.4 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0071335 proximal/distal axis specification(GO:0009946) bronchiole development(GO:0060435) submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.2 GO:0046449 creatinine metabolic process(GO:0046449) cellular response to UV-A(GO:0071492)
0.0 0.3 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.3 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 2.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.3 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.0 0.4 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.1 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.1 GO:0098907 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0 1.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.5 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0 0.5 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.3 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.1 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.0 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.3 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.2 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0003360 brainstem development(GO:0003360)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.0 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.4 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:0060371 response to pyrethroid(GO:0046684) regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.5 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0044254 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.3 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.7 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.0 GO:0070781 response to biotin(GO:0070781)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.0 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.6 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.0 0.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 1.6 GO:0035838 growing cell tip(GO:0035838)
0.1 0.6 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 1.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.4 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.2 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 0.2 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.1 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.4 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787) synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.0 GO:0044301 climbing fiber(GO:0044301)
0.0 2.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.0 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.4 1.6 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.3 1.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.2 0.9 GO:0035501 MH1 domain binding(GO:0035501)
0.2 1.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.4 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 1.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.3 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.6 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.3 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 0.5 GO:0050816 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 0.5 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0031957 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238) N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.5 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 0.2 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 1.0 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0001069 regulatory region RNA binding(GO:0001069)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 1.6 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.6 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.6 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.2 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.2 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 1.7 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 PID_INTEGRIN1_PATHWAY Beta1 integrin cell surface interactions
0.0 0.7 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.7 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.4 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 0.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.6 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 1.0 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.2 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.1 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 0.6 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 NABA_COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 1.5 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME_OPSINS Genes involved in Opsins
0.0 0.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 1.0 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.3 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.4 REACTOME_JNK_C_JUN_KINASES_PHOSPHORYLATION_AND_ACTIVATION_MEDIATED_BY_ACTIVATED_HUMAN_TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.1 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere