Motif ID: CACAGUG

Z-value: 0.448


Mature miRNA associated with seed CACAGUG:

NamemiRBase Accession
hsa-miR-128-3p MIMAT0000424
hsa-miR-216a-3p MIMAT0022844
hsa-miR-3681-3p MIMAT0018109



Activity profile for motif CACAGUG.

activity profile for motif CACAGUG


Sorted Z-values histogram for motif CACAGUG

Sorted Z-values for motif CACAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of CACAGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_7921090 1.281 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr20_-_50419055 0.623 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr4_-_107957454 0.565 ENST00000285311.3
DKK2
dickkopf WNT signaling pathway inhibitor 2
chr16_+_66878814 0.540 ENST00000394069.3
CA7
carbonic anhydrase VII
chr11_-_123525289 0.527 ENST00000392770.2
ENST00000299333.3
ENST00000530277.1
SCN3B


sodium channel, voltage-gated, type III, beta subunit


chr4_+_5053162 0.395 ENST00000282908.5
STK32B
serine/threonine kinase 32B
chrX_+_78426469 0.377 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chr20_-_41818373 0.363 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT



protein tyrosine phosphatase, receptor type, T



chr15_+_29131103 0.320 ENST00000558402.1
ENST00000558330.1
APBA2

amyloid beta (A4) precursor protein-binding, family A, member 2

chr15_-_82641706 0.315 ENST00000439287.4
GOLGA6L10
golgin A6 family-like 10
chr17_-_50237343 0.314 ENST00000575181.1
ENST00000570565.1
CA10

carbonic anhydrase X

chr15_-_82939157 0.306 ENST00000559949.1
RP13-996F3.5
golgin A6 family-like 18
chr22_-_37099555 0.297 ENST00000300105.6
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chrX_+_64708615 0.296 ENST00000338957.4
ENST00000423889.3
ZC3H12B

zinc finger CCCH-type containing 12B

chr8_+_1922024 0.290 ENST00000320248.3
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr15_-_83018198 0.281 ENST00000557886.1
RP13-996F3.4
golgin A6 family-like 19
chr5_-_157002775 0.278 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr16_+_77822427 0.273 ENST00000302536.2
VAT1L
vesicle amine transport 1-like
chr11_-_30038490 0.267 ENST00000328224.6
KCNA4
potassium voltage-gated channel, shaker-related subfamily, member 4
chr1_+_215256467 0.261 ENST00000391894.2
ENST00000444842.2
KCNK2

potassium channel, subfamily K, member 2

chr3_+_139654018 0.259 ENST00000458420.3
CLSTN2
calsyntenin 2
chr6_+_118228657 0.253 ENST00000360388.4
SLC35F1
solute carrier family 35, member F1
chr12_+_40787194 0.252 ENST00000425730.2
ENST00000454784.4
MUC19

mucin 19, oligomeric

chr6_-_119399895 0.251 ENST00000338891.7
FAM184A
family with sequence similarity 184, member A
chr14_-_53619816 0.249 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD1


DDHD domain containing 1


chr1_-_179198702 0.241 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr18_+_49866496 0.240 ENST00000442544.2
DCC
deleted in colorectal carcinoma
chr12_+_54943134 0.240 ENST00000243052.3
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr3_+_11034403 0.236 ENST00000287766.4
ENST00000425938.1
SLC6A1

solute carrier family 6 (neurotransmitter transporter), member 1

chrX_+_16804544 0.234 ENST00000380122.5
ENST00000398155.4
TXLNG

taxilin gamma

chr5_-_1524015 0.223 ENST00000283415.3
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr22_-_39239987 0.220 ENST00000333039.2
NPTXR
neuronal pentraxin receptor
chrX_+_150151752 0.217 ENST00000325307.7
HMGB3
high mobility group box 3
chr7_+_6144514 0.216 ENST00000306177.5
ENST00000465073.2
USP42

ubiquitin specific peptidase 42

chr6_-_24911195 0.213 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr17_-_53499310 0.211 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr5_-_57756087 0.209 ENST00000274289.3
PLK2
polo-like kinase 2
chr19_-_7293942 0.204 ENST00000341500.5
ENST00000302850.5
INSR

insulin receptor

chr3_+_36421826 0.204 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr3_-_39195037 0.197 ENST00000273153.5
CSRNP1
cysteine-serine-rich nuclear protein 1
chr11_+_14665263 0.195 ENST00000282096.4
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr9_+_118916082 0.195 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr12_+_3600356 0.193 ENST00000382622.3
PRMT8
protein arginine methyltransferase 8
chr13_+_113622810 0.192 ENST00000397030.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr19_+_51815102 0.190 ENST00000270642.8
IGLON5
IgLON family member 5
chrX_-_54384425 0.189 ENST00000375169.3
ENST00000354646.2
WNK3

WNK lysine deficient protein kinase 3

chr2_+_7057523 0.183 ENST00000320892.6
RNF144A
ring finger protein 144A
chr22_+_46067678 0.183 ENST00000381061.4
ENST00000252934.5
ATXN10

ataxin 10

chr19_-_344786 0.182 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr14_+_103243813 0.182 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3




TNF receptor-associated factor 3




chrX_-_3631635 0.181 ENST00000262848.5
PRKX
protein kinase, X-linked
chr17_-_46692287 0.180 ENST00000239144.4
HOXB8
homeobox B8
chr14_+_56585048 0.179 ENST00000267460.4
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr9_-_130742792 0.175 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr4_+_140222609 0.172 ENST00000296543.5
ENST00000398947.1
NAA15

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

chr12_+_54422142 0.172 ENST00000243108.4
HOXC6
homeobox C6
chr12_-_77459306 0.171 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F7



E2F transcription factor 7



chr11_-_74109422 0.170 ENST00000298198.4
PGM2L1
phosphoglucomutase 2-like 1
chrX_+_49687216 0.169 ENST00000376088.3
CLCN5
chloride channel, voltage-sensitive 5
chr14_-_30396948 0.168 ENST00000331968.5
PRKD1
protein kinase D1
chr19_+_19322758 0.167 ENST00000252575.6
NCAN
neurocan
chr3_+_119187785 0.167 ENST00000295588.4
ENST00000476573.1
POGLUT1

protein O-glucosyltransferase 1

chr16_-_68482440 0.167 ENST00000219334.5
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr2_-_25142708 0.166 ENST00000260600.5
ENST00000435135.1
ADCY3

adenylate cyclase 3

chr6_-_46293378 0.165 ENST00000330430.6
RCAN2
regulator of calcineurin 2
chr10_+_31608054 0.165 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1





zinc finger E-box binding homeobox 1





chr9_+_116638562 0.165 ENST00000374126.5
ENST00000288466.7
ZNF618

zinc finger protein 618

chr2_-_100721178 0.164 ENST00000409236.2
AFF3
AF4/FMR2 family, member 3
chr7_+_21467642 0.162 ENST00000222584.3
ENST00000432066.2
SP4

Sp4 transcription factor

chrX_+_14547632 0.161 ENST00000218075.4
GLRA2
glycine receptor, alpha 2
chr17_+_56160768 0.157 ENST00000579991.2
DYNLL2
dynein, light chain, LC8-type 2
chr21_+_33245548 0.156 ENST00000270112.2
HUNK
hormonally up-regulated Neu-associated kinase
chr2_-_40679186 0.155 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr5_+_76506706 0.154 ENST00000340978.3
ENST00000346042.3
ENST00000264917.5
ENST00000342343.4
ENST00000333194.4
PDE8B




phosphodiesterase 8B




chr20_+_10199468 0.153 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chr17_-_7232585 0.150 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
NEURL4



neuralized E3 ubiquitin protein ligase 4



chr6_-_107436473 0.148 ENST00000369042.1
BEND3
BEN domain containing 3
chr5_-_179780312 0.147 ENST00000253778.8
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr4_+_56815102 0.144 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr4_-_174451370 0.142 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr18_+_54318616 0.141 ENST00000254442.3
WDR7
WD repeat domain 7
chr12_+_32112340 0.140 ENST00000540924.1
ENST00000312561.4
KIAA1551

KIAA1551

chr5_+_65018017 0.140 ENST00000380985.5
ENST00000502464.1
NLN

neurolysin (metallopeptidase M3 family)

chr18_-_268019 0.138 ENST00000261600.6
THOC1
THO complex 1
chr2_-_119605253 0.137 ENST00000295206.6
EN1
engrailed homeobox 1
chrX_-_129402857 0.136 ENST00000447817.1
ENST00000370978.4
ZNF280C

zinc finger protein 280C

chr14_-_59932044 0.135 ENST00000395116.1
GPR135
G protein-coupled receptor 135
chr6_+_126112001 0.132 ENST00000392477.2
NCOA7
nuclear receptor coactivator 7
chrX_+_72783026 0.129 ENST00000373504.6
ENST00000373502.5
CHIC1

cysteine-rich hydrophobic domain 1

chr12_+_113495492 0.128 ENST00000257600.3
DTX1
deltex homolog 1 (Drosophila)
chr15_+_73344791 0.128 ENST00000261908.6
NEO1
neogenin 1
chr16_-_4588822 0.128 ENST00000564828.1
CDIP1
cell death-inducing p53 target 1
chr1_+_54519242 0.127 ENST00000234827.1
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chrX_+_37430822 0.125 ENST00000378621.3
ENST00000378619.3
LANCL3

LanC lantibiotic synthetase component C-like 3 (bacterial)

chrX_+_142967173 0.125 ENST00000370494.1
UBE2NL
ubiquitin-conjugating enzyme E2N-like
chr12_-_90049828 0.124 ENST00000261173.2
ENST00000348959.3
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr4_+_6784401 0.124 ENST00000425103.1
ENST00000307659.5
KIAA0232

KIAA0232

chr7_+_138916231 0.124 ENST00000473989.3
ENST00000288561.8
UBN2

ubinuclein 2

chr2_+_155554797 0.124 ENST00000295101.2
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr5_+_152870106 0.124 ENST00000285900.5
GRIA1
glutamate receptor, ionotropic, AMPA 1
chr4_-_24914508 0.123 ENST00000504487.1
CCDC149
coiled-coil domain containing 149
chr3_-_21792838 0.123 ENST00000281523.2
ZNF385D
zinc finger protein 385D
chr12_+_79258547 0.123 ENST00000457153.2
SYT1
synaptotagmin I
chr10_+_127408263 0.121 ENST00000337623.3
C10orf137
erythroid differentiation regulatory factor 1
chr10_+_81107216 0.120 ENST00000394579.3
ENST00000225174.3
PPIF

peptidylprolyl isomerase F

chr19_+_19496624 0.120 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATAD2A


GATA zinc finger domain containing 2A


chr19_+_50094866 0.120 ENST00000418929.2
PRR12
proline rich 12
chr8_-_8751068 0.119 ENST00000276282.6
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr1_+_101361626 0.118 ENST00000370112.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr12_-_12419703 0.117 ENST00000543091.1
ENST00000261349.4
LRP6

low density lipoprotein receptor-related protein 6

chr15_+_41221536 0.117 ENST00000249749.5
DLL4
delta-like 4 (Drosophila)
chrX_-_25034065 0.116 ENST00000379044.4
ARX
aristaless related homeobox
chr15_+_76352178 0.116 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr1_-_149889382 0.116 ENST00000369145.1
ENST00000369146.3
SV2A

synaptic vesicle glycoprotein 2A

chr15_+_54305101 0.115 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
UNC13C


unc-13 homolog C (C. elegans)


chr19_+_1286097 0.115 ENST00000215368.2
EFNA2
ephrin-A2
chr1_+_180601139 0.115 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr14_+_71374122 0.114 ENST00000304743.2
ENST00000238570.5
PCNX

pecanex homolog (Drosophila)

chr17_+_55333876 0.113 ENST00000284073.2
MSI2
musashi RNA-binding protein 2
chr1_+_38259540 0.113 ENST00000397631.3
MANEAL
mannosidase, endo-alpha-like
chr17_+_12569306 0.113 ENST00000425538.1
MYOCD
myocardin
chr9_-_127905736 0.113 ENST00000336505.6
ENST00000373549.4
SCAI

suppressor of cancer cell invasion

chr4_-_13546632 0.112 ENST00000382438.5
NKX3-2
NK3 homeobox 2
chr17_-_47492236 0.111 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
PHB



prohibitin



chr2_-_227664474 0.110 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr9_+_103790991 0.109 ENST00000374874.3
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr22_+_39898325 0.107 ENST00000325301.2
ENST00000404569.1
MIEF1

mitochondrial elongation factor 1

chr9_+_116917807 0.107 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr19_+_41222998 0.107 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr14_-_92413727 0.106 ENST00000267620.10
FBLN5
fibulin 5
chr15_-_56209306 0.105 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4


neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase


chr14_+_100259666 0.105 ENST00000262233.6
ENST00000334192.4
EML1

echinoderm microtubule associated protein like 1

chr16_+_66914264 0.105 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2




pyruvate dehyrogenase phosphatase catalytic subunit 2




chr6_+_136172820 0.105 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr7_-_31380502 0.105 ENST00000297142.3
NEUROD6
neuronal differentiation 6
chr2_-_54087066 0.104 ENST00000352846.3
ENST00000394705.2
ENST00000406625.2
GPR75-ASB3
GPR75
ASB3
GPR75-ASB3 readthrough
G protein-coupled receptor 75
Ankyrin repeat and SOCS box protein 3
chr11_+_109964087 0.102 ENST00000278590.3
ZC3H12C
zinc finger CCCH-type containing 12C
chr19_+_38397839 0.102 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr19_+_15218180 0.101 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1


synapse defective 1, Rho GTPase, homolog 1 (C. elegans)


chr20_-_60982330 0.101 ENST00000279101.5
CABLES2
Cdk5 and Abl enzyme substrate 2
chr8_-_81787006 0.099 ENST00000327835.3
ZNF704
zinc finger protein 704
chr8_-_91658303 0.099 ENST00000458549.2
TMEM64
transmembrane protein 64
chr7_-_92219698 0.099 ENST00000438306.1
ENST00000445716.1
FAM133B

family with sequence similarity 133, member B

chr10_-_71930222 0.098 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1A



SAR1 homolog A (S. cerevisiae)



chr1_-_78444776 0.097 ENST00000370767.1
ENST00000421641.1
FUBP1

far upstream element (FUSE) binding protein 1

chr21_-_28338732 0.096 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr11_-_118661828 0.096 ENST00000264018.4
DDX6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr13_-_103053946 0.096 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr9_-_140196703 0.096 ENST00000356628.2
NRARP
NOTCH-regulated ankyrin repeat protein
chr6_-_166075557 0.095 ENST00000539869.2
ENST00000366882.1
PDE10A

phosphodiesterase 10A

chr1_+_26737253 0.095 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr1_-_47697387 0.095 ENST00000371884.2
TAL1
T-cell acute lymphocytic leukemia 1
chr3_+_150804676 0.094 ENST00000474524.1
ENST00000273432.4
MED12L

mediator complex subunit 12-like

chr7_+_24612935 0.094 ENST00000222644.5
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr5_+_7396141 0.093 ENST00000338316.4
ADCY2
adenylate cyclase 2 (brain)
chr9_-_23821273 0.093 ENST00000380110.4
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chrX_+_105066524 0.092 ENST00000243300.9
ENST00000428173.2
NRK

Nik related kinase

chr16_-_71758602 0.092 ENST00000568954.1
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr4_+_160188889 0.092 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr3_-_171178157 0.092 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK




TRAF2 and NCK interacting kinase




chr10_+_104474207 0.090 ENST00000602831.1
ENST00000369893.5
SFXN2

sideroflexin 2

chr17_+_47865917 0.090 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
KAT7




K(lysine) acetyltransferase 7




chr9_-_88714421 0.088 ENST00000388712.3
GOLM1
golgi membrane protein 1
chr4_+_79697495 0.088 ENST00000502871.1
ENST00000335016.5
BMP2K

BMP2 inducible kinase

chr1_-_92351769 0.087 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr1_+_36396677 0.087 ENST00000373191.4
ENST00000397828.2
AGO3

argonaute RISC catalytic component 3

chr3_-_24536253 0.087 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB





thyroid hormone receptor, beta





chr1_+_76540386 0.086 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr9_+_129089088 0.084 ENST00000361171.3
ENST00000545391.1
MVB12B

multivesicular body subunit 12B

chr1_+_203274639 0.084 ENST00000290551.4
BTG2
BTG family, member 2
chr20_+_2673383 0.083 ENST00000380648.4
ENST00000342725.5
EBF4

early B-cell factor 4

chr1_-_35395178 0.082 ENST00000373347.1
DLGAP3
discs, large (Drosophila) homolog-associated protein 3
chr5_-_132073210 0.082 ENST00000378735.1
ENST00000378746.4
KIF3A

kinesin family member 3A

chr11_+_66234216 0.082 ENST00000349459.6
ENST00000320740.7
ENST00000524466.1
ENST00000526296.1
PELI3



pellino E3 ubiquitin protein ligase family member 3



chr19_+_48898132 0.081 ENST00000263269.3
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr22_-_37823468 0.081 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr3_+_54156664 0.081 ENST00000474759.1
ENST00000288197.5
CACNA2D3

calcium channel, voltage-dependent, alpha 2/delta subunit 3

chr12_-_93835665 0.080 ENST00000552442.1
ENST00000550657.1
UBE2N

ubiquitin-conjugating enzyme E2N

chr9_+_129376722 0.079 ENST00000526117.1
ENST00000373474.4
ENST00000355497.5
ENST00000425646.2
ENST00000561065.1
LMX1B




LIM homeobox transcription factor 1, beta




chr2_-_11606275 0.078 ENST00000381525.3
ENST00000362009.4
E2F6

E2F transcription factor 6

chr11_-_60674037 0.078 ENST00000541371.1
ENST00000227524.4
PRPF19

pre-mRNA processing factor 19

chr10_+_70320413 0.078 ENST00000373644.4
TET1
tet methylcytosine dioxygenase 1
chr16_-_73082274 0.077 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr5_+_143584814 0.076 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr13_-_107187462 0.076 ENST00000245323.4
EFNB2
ephrin-B2
chr22_+_21271714 0.076 ENST00000354336.3
CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
chr6_+_44238203 0.075 ENST00000451188.2
TMEM151B
transmembrane protein 151B
chr13_-_50367057 0.074 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr4_+_113970772 0.074 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2



ankyrin 2, neuronal



chr17_-_62658186 0.074 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr19_+_32896697 0.073 ENST00000586987.1
DPY19L3
dpy-19-like 3 (C. elegans)
chr18_-_23670546 0.073 ENST00000542743.1
ENST00000545952.1
ENST00000539849.1
ENST00000415083.2
SS18



synovial sarcoma translocation, chromosome 18



chr1_-_225840747 0.072 ENST00000366843.2
ENST00000366844.3
ENAH

enabled homolog (Drosophila)

chr12_-_82153087 0.072 ENST00000547623.1
ENST00000549396.1
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr3_-_141868357 0.072 ENST00000489671.1
ENST00000475734.1
ENST00000467072.1
ENST00000499676.2
TFDP2



transcription factor Dp-2 (E2F dimerization partner 2)



chr9_-_135819987 0.072 ENST00000298552.3
ENST00000403810.1
TSC1

tuberous sclerosis 1

chr4_+_3076388 0.071 ENST00000355072.5
HTT
huntingtin
chr6_+_1312675 0.070 ENST00000296839.2
FOXQ1
forkhead box Q1
chrX_-_80065146 0.070 ENST00000373275.4
BRWD3
bromodomain and WD repeat domain containing 3
chr20_+_48599506 0.070 ENST00000244050.2
SNAI1
snail family zinc finger 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.5 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.5 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.2 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.2 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.2 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.2 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.2 GO:0008355 olfactory learning(GO:0008355)
0.1 0.2 GO:1990535 transformation of host cell by virus(GO:0019087) neuron projection maintenance(GO:1990535)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.1 GO:1900222 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0045799 positive regulation of chromatin assembly or disassembly(GO:0045799)
0.0 0.1 GO:0060721 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0072554 blood vessel lumenization(GO:0072554)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0061032 cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.1 GO:0098907 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.1 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0042428 serotonin metabolic process(GO:0042428)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.0 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.0 0.0 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.0 GO:0060574 bronchiole development(GO:0060435) intestinal epithelial cell maturation(GO:0060574)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.0 0.2 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.4 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.0 GO:1904674 regulation of somatic stem cell population maintenance(GO:1904672) positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.0 GO:0002071 columnar/cuboidal epithelial cell maturation(GO:0002069) glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.0 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.0 GO:0048320 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) axial mesoderm formation(GO:0048320) canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.0 GO:0007497 posterior midgut development(GO:0007497)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044305 calyx of Held(GO:0044305)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 1.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.0 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.8 PID_PS1_PATHWAY Presenilin action in Notch and Wnt signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects