Motif ID: BARHL2

Z-value: 1.409


Transcription factors associated with BARHL2:

Gene SymbolEntrez IDGene Name
BARHL2 ENSG00000143032.7 BARHL2



Activity profile for motif BARHL2.

activity profile for motif BARHL2


Sorted Z-values histogram for motif BARHL2

Sorted Z-values for motif BARHL2



Network of associatons between targets according to the STRING database.



First level regulatory network of BARHL2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_208031943 5.304 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr5_+_31193847 4.978 ENST00000514738.1
ENST00000265071.2
CDH6

cadherin 6, type 2, K-cadherin (fetal kidney)

chr4_+_69313145 4.852 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr18_+_29027696 4.761 ENST00000257189.4
DSG3
desmoglein 3
chr6_+_151646800 4.464 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr12_-_89746173 4.117 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr12_+_107712173 3.931 ENST00000280758.5
ENST00000420571.2
BTBD11

BTB (POZ) domain containing 11

chr18_+_21529811 3.908 ENST00000588004.1
LAMA3
laminin, alpha 3
chr17_-_38859996 3.879 ENST00000264651.2
KRT24
keratin 24
chr16_-_46655538 3.823 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr12_-_25055177 3.611 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr2_-_238322800 3.603 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
COL6A3





collagen, type VI, alpha 3





chr17_+_70117153 3.425 ENST00000245479.2
SOX9
SRY (sex determining region Y)-box 9
chr5_-_146781153 3.422 ENST00000520473.1
DPYSL3
dihydropyrimidinase-like 3
chr19_-_43382142 3.327 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chrX_+_135251783 3.165 ENST00000394153.2
FHL1
four and a half LIM domains 1
chrX_+_135252050 3.154 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chr2_-_238323007 3.150 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr16_+_50300427 3.082 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
ADCY7


adenylate cyclase 7


chr2_+_158114051 3.024 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr18_+_34124507 3.019 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr7_+_107224364 2.978 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr2_-_238322770 2.944 ENST00000472056.1
COL6A3
collagen, type VI, alpha 3
chr6_+_34204642 2.943 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr12_-_10978957 2.892 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chrX_+_135251835 2.885 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr4_+_169013666 2.821 ENST00000359299.3
ANXA10
annexin A10
chrX_-_153602991 2.788 ENST00000369850.3
ENST00000422373.1
FLNA

filamin A, alpha

chr4_-_143227088 2.725 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr5_-_139726181 2.604 ENST00000507104.1
ENST00000230990.6
HBEGF

heparin-binding EGF-like growth factor

chr7_-_25019760 2.567 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
OSBPL3



oxysterol binding protein-like 3



chr16_+_8806800 2.552 ENST00000561870.1
ENST00000396600.2
ABAT

4-aminobutyrate aminotransferase

chr1_+_203651937 2.480 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr18_+_21452964 2.249 ENST00000587184.1
LAMA3
laminin, alpha 3
chr11_+_35201826 2.172 ENST00000531873.1
CD44
CD44 molecule (Indian blood group)
chr12_-_91505608 2.140 ENST00000266718.4
LUM
lumican
chr8_-_49833978 2.111 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr5_+_150639360 2.062 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr8_+_22424551 2.035 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr11_+_33061543 2.009 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1


t-complex 11, testis-specific-like 1


chr1_+_152974218 2.007 ENST00000331860.3
ENST00000443178.1
ENST00000295367.4
SPRR3


small proline-rich protein 3


chr5_+_162887556 1.996 ENST00000393915.4
ENST00000432118.2
ENST00000358715.3
HMMR


hyaluronan-mediated motility receptor (RHAMM)


chr17_-_57229155 1.983 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr9_+_5450503 1.971 ENST00000381573.4
ENST00000381577.3
CD274

CD274 molecule

chr12_+_110011571 1.971 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK


mevalonate kinase


chr18_+_21452804 1.936 ENST00000269217.6
LAMA3
laminin, alpha 3
chr1_-_152386732 1.865 ENST00000271835.3
CRNN
cornulin
chr12_-_95510743 1.850 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr9_-_95640218 1.840 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484


zinc finger protein 484


chr11_+_64018955 1.814 ENST00000279230.6
ENST00000540288.1
ENST00000325234.5
PLCB3


phospholipase C, beta 3 (phosphatidylinositol-specific)


chr8_-_49834299 1.804 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr9_+_132099158 1.795 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr3_+_156799587 1.785 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr1_+_84630053 1.777 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr14_+_68086515 1.770 ENST00000261783.3
ARG2
arginase 2
chr6_-_131384347 1.769 ENST00000530481.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr2_-_188419078 1.747 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI



tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)



chr18_-_67873078 1.732 ENST00000255674.6
RTTN
rotatin
chr19_+_41257084 1.719 ENST00000601393.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chrX_-_71351678 1.708 ENST00000609883.1
ENST00000545866.1
RGAG4

retrotransposon gag domain containing 4

chr19_-_44285401 1.699 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr14_+_73706308 1.690 ENST00000554301.1
ENST00000555445.1
PAPLN

papilin, proteoglycan-like sulfated glycoprotein

chr8_-_125486755 1.675 ENST00000499418.2
ENST00000530778.1
RNF139-AS1

RNF139 antisense RNA 1 (head to head)

chr12_+_15699286 1.640 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO



protein tyrosine phosphatase, receptor type, O



chr11_-_107590383 1.637 ENST00000525934.1
ENST00000531293.1
SLN

sarcolipin

chr4_+_106631966 1.623 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD


glutathione S-transferase, C-terminal domain containing


chr3_+_130569429 1.613 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr14_+_32798547 1.609 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6


A kinase (PRKA) anchor protein 6


chr1_-_110933611 1.606 ENST00000472422.2
ENST00000437429.2
SLC16A4

solute carrier family 16, member 4

chr14_-_91720224 1.584 ENST00000238699.3
ENST00000531499.2
GPR68

G protein-coupled receptor 68

chr1_-_110933663 1.577 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4


solute carrier family 16, member 4


chr4_-_159956333 1.570 ENST00000434826.2
C4orf45
chromosome 4 open reading frame 45
chr8_-_62559366 1.539 ENST00000522919.1
ASPH
aspartate beta-hydroxylase
chr14_-_57272366 1.537 ENST00000554788.1
ENST00000554845.1
ENST00000408990.3
OTX2


orthodenticle homeobox 2


chr2_+_102456277 1.531 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr18_+_61254570 1.517 ENST00000344731.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr15_-_42264702 1.514 ENST00000220325.4
EHD4
EH-domain containing 4
chr1_+_62439037 1.513 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr7_+_13141097 1.510 ENST00000411542.1
AC011288.2
AC011288.2
chr3_+_130569592 1.492 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr18_-_31803169 1.472 ENST00000590712.1
NOL4
nucleolar protein 4
chr11_+_12308447 1.450 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr14_-_107283278 1.449 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr1_+_209878182 1.441 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr18_+_56530136 1.425 ENST00000591083.1
ZNF532
zinc finger protein 532
chr11_-_118135160 1.423 ENST00000438295.2
MPZL2
myelin protein zero-like 2
chr17_-_17184605 1.408 ENST00000268717.5
COPS3
COP9 signalosome subunit 3
chr19_-_51537982 1.392 ENST00000525263.1
KLK12
kallikrein-related peptidase 12
chr3_+_182971018 1.391 ENST00000326505.3
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr15_+_40674920 1.385 ENST00000416151.2
ENST00000249776.8
KNSTRN

kinetochore-localized astrin/SPAG5 binding protein

chr1_+_63063152 1.383 ENST00000371129.3
ANGPTL3
angiopoietin-like 3
chr17_-_39254391 1.381 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr12_-_53171128 1.381 ENST00000332411.2
KRT76
keratin 76
chr22_-_50523760 1.370 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr7_+_142458507 1.369 ENST00000492062.1
PRSS1
protease, serine, 1 (trypsin 1)
chr19_+_15838834 1.369 ENST00000305899.3
OR10H2
olfactory receptor, family 10, subfamily H, member 2
chr7_-_107443652 1.362 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3


solute carrier family 26 (anion exchanger), member 3


chr19_-_43708378 1.362 ENST00000599746.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr1_-_150780757 1.351 ENST00000271651.3
CTSK
cathepsin K
chr3_+_111630451 1.335 ENST00000495180.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr6_+_106546808 1.329 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr17_-_7307358 1.324 ENST00000535512.1
ENST00000576017.1
ENST00000302422.3
TMEM256-PLSCR3
TMEM256

TMEM256-PLSCR3 readthrough (NMD candidate)
transmembrane protein 256

chr19_+_45409011 1.318 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE


apolipoprotein E


chr6_+_26199737 1.302 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr14_+_32798462 1.296 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr3_+_189349162 1.283 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63





tumor protein p63





chr1_+_115572415 1.267 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr21_-_31869451 1.263 ENST00000334058.2
KRTAP19-4
keratin associated protein 19-4
chr6_+_130339710 1.262 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr3_-_149093499 1.257 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr6_-_29055090 1.256 ENST00000377173.2
OR2B3
olfactory receptor, family 2, subfamily B, member 3
chr10_-_95242044 1.255 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF


myoferlin


chr11_+_72983246 1.241 ENST00000393590.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr6_+_106534192 1.232 ENST00000369091.2
ENST00000369096.4
PRDM1

PR domain containing 1, with ZNF domain

chr17_-_39211463 1.232 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr14_-_60097297 1.230 ENST00000395090.1
RTN1
reticulon 1
chr4_+_71200681 1.217 ENST00000273936.5
CABS1
calcium-binding protein, spermatid-specific 1
chr6_-_111927062 1.212 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr15_-_64665911 1.198 ENST00000606793.1
ENST00000561349.1
ENST00000560278.1
CTD-2116N17.1


Uncharacterized protein


chr13_+_32313658 1.188 ENST00000380314.1
ENST00000298386.2
RXFP2

relaxin/insulin-like family peptide receptor 2

chr8_+_11666649 1.185 ENST00000528643.1
ENST00000525777.1
FDFT1

farnesyl-diphosphate farnesyltransferase 1

chr9_+_116263778 1.176 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr19_-_51538118 1.175 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr1_+_50569575 1.160 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr9_-_95244781 1.156 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN



asporin



chr12_-_72057638 1.150 ENST00000552037.1
ENST00000378743.3
ZFC3H1

zinc finger, C3H1-type containing

chr20_+_60174827 1.150 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr5_+_54320078 1.147 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr7_+_77469439 1.143 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2


putative homeodomain transcription factor 2


chr2_+_33359646 1.137 ENST00000390003.4
ENST00000418533.2
LTBP1

latent transforming growth factor beta binding protein 1

chr19_-_51538148 1.132 ENST00000319590.4
ENST00000250351.4
KLK12

kallikrein-related peptidase 12

chr4_+_71587669 1.132 ENST00000381006.3
ENST00000226328.4
RUFY3

RUN and FYVE domain containing 3

chr4_-_39979576 1.131 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr14_-_60097524 1.127 ENST00000342503.4
RTN1
reticulon 1
chr14_-_24740709 1.116 ENST00000399409.3
ENST00000216840.6
RABGGTA

Rab geranylgeranyltransferase, alpha subunit

chr4_+_144303093 1.104 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr5_-_125930929 1.095 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
ALDH7A1


aldehyde dehydrogenase 7 family, member A1


chr12_+_72058130 1.093 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr3_-_149095652 1.093 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr10_-_14372870 1.084 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr3_+_150126101 1.084 ENST00000361875.3
ENST00000361136.2
TSC22D2

TSC22 domain family, member 2

chr15_+_40674963 1.072 ENST00000448395.2
KNSTRN
kinetochore-localized astrin/SPAG5 binding protein
chr4_-_143226979 1.070 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chrX_+_49832231 1.067 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr6_+_29141311 1.067 ENST00000377167.2
OR2J2
olfactory receptor, family 2, subfamily J, member 2
chr17_-_64225508 1.066 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr7_+_129984630 1.062 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5








carboxypeptidase A5








chr8_+_32579341 1.061 ENST00000519240.1
ENST00000539990.1
NRG1

neuregulin 1

chr2_+_204732666 1.055 ENST00000295854.6
ENST00000472206.1
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr4_-_74853897 1.055 ENST00000296028.3
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr7_-_14026123 1.053 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1


ets variant 1


chr22_-_36357671 1.045 ENST00000408983.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr4_+_37828255 1.042 ENST00000381967.4
ENST00000544359.1
ENST00000537241.1
PGM2


phosphoglucomutase 2


chr8_-_23712312 1.036 ENST00000290271.2
STC1
stanniocalcin 1
chrX_-_18690210 1.023 ENST00000379984.3
RS1
retinoschisin 1
chr3_-_178984759 1.021 ENST00000349697.2
ENST00000497599.1
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr3_-_55001115 1.005 ENST00000493075.1
LRTM1
leucine-rich repeats and transmembrane domains 1
chr2_+_171034646 0.993 ENST00000409044.3
ENST00000408978.4
MYO3B

myosin IIIB

chrX_-_55057403 0.991 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
ALAS2



aminolevulinate, delta-, synthase 2



chr10_-_29923893 0.991 ENST00000355867.4
SVIL
supervillin
chr1_-_89641680 0.990 ENST00000294671.2
GBP7
guanylate binding protein 7
chr11_-_121986923 0.988 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr4_+_41258786 0.986 ENST00000503431.1
ENST00000284440.4
ENST00000508768.1
ENST00000512788.1
UCHL1



ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)



chr7_-_14026063 0.986 ENST00000443608.1
ENST00000438956.1
ETV1

ets variant 1

chr6_-_49604545 0.982 ENST00000371175.4
ENST00000229810.7
RHAG

Rh-associated glycoprotein

chr3_+_182971583 0.972 ENST00000460419.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr19_+_39687596 0.971 ENST00000339852.4
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr2_-_166930131 0.968 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr17_-_10276319 0.950 ENST00000252172.4
ENST00000418404.3
MYH13

myosin, heavy chain 13, skeletal muscle

chr15_+_40675132 0.945 ENST00000608100.1
ENST00000557920.1
KNSTRN

kinetochore-localized astrin/SPAG5 binding protein

chr9_-_93405352 0.941 ENST00000375765.3
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr4_+_155484103 0.939 ENST00000302068.4
FGB
fibrinogen beta chain
chr10_+_106034637 0.933 ENST00000401888.2
GSTO2
glutathione S-transferase omega 2
chr10_-_105110890 0.931 ENST00000369847.3
PCGF6
polycomb group ring finger 6
chr3_-_47934234 0.927 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr18_-_57027194 0.927 ENST00000251047.5
LMAN1
lectin, mannose-binding, 1
chr1_+_44401479 0.913 ENST00000438616.3
ARTN
artemin
chr17_+_66521936 0.896 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr4_+_86525299 0.892 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr10_+_18629628 0.891 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr18_+_29171689 0.887 ENST00000237014.3
TTR
transthyretin
chr4_+_155484155 0.885 ENST00000509493.1
FGB
fibrinogen beta chain
chr2_+_87808725 0.881 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr11_+_65686802 0.879 ENST00000376991.2
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr4_+_169418255 0.875 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr1_-_205649580 0.873 ENST00000367145.3
SLC45A3
solute carrier family 45, member 3
chrX_+_70521584 0.872 ENST00000373829.3
ENST00000538820.1
ITGB1BP2

integrin beta 1 binding protein (melusin) 2

chr8_+_31496809 0.857 ENST00000518104.1
ENST00000519301.1
NRG1

neuregulin 1

chrX_+_114827818 0.857 ENST00000420625.2
PLS3
plastin 3
chr4_-_90756769 0.855 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr4_+_40198527 0.855 ENST00000381799.5
RHOH
ras homolog family member H
chr4_-_152149033 0.855 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr13_-_38172863 0.852 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN





periostin, osteoblast specific factor





chr2_-_172290482 0.850 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
METTL8


methyltransferase like 8


chr18_+_55816546 0.850 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr3_-_113897545 0.847 ENST00000467632.1
DRD3
dopamine receptor D3
chr1_+_155278539 0.844 ENST00000447866.1
FDPS
farnesyl diphosphate synthase
chr3_-_116163830 0.844 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr10_+_5238793 0.844 ENST00000263126.1
AKR1C4
aldo-keto reductase family 1, member C4
chr4_-_103997862 0.843 ENST00000394785.3
SLC9B2
solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
1.3 3.9 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.1 3.4 GO:0060516 primary prostatic bud elongation(GO:0060516) renal vesicle induction(GO:0072034)
0.8 2.5 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.8 3.1 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.7 0.7 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.7 2.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.6 3.6 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.6 2.9 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.5 1.6 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.5 1.6 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.5 3.7 GO:0051136 regulation of NK T cell differentiation(GO:0051136)
0.5 2.6 GO:0051541 elastin metabolic process(GO:0051541)
0.5 3.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.5 2.9 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.5 2.8 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.4 1.3 GO:2000646 regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of receptor catabolic process(GO:2000646)
0.4 1.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.4 1.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 1.9 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.4 1.1 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.3 2.8 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.3 1.0 GO:0007412 axon target recognition(GO:0007412)
0.3 1.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.3 2.6 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.3 1.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.3 4.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.3 0.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.3 1.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.3 2.0 GO:0097338 response to clozapine(GO:0097338)
0.3 0.8 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.3 2.0 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.3 8.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 1.9 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.3 2.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 2.1 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.3 3.4 GO:0051764 actin crosslink formation(GO:0051764)
0.3 1.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 3.9 GO:0051639 actin filament network formation(GO:0051639)
0.2 1.4 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 0.7 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.2 1.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2 0.7 GO:0018874 benzoate metabolic process(GO:0018874)
0.2 2.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.2 0.9 GO:0031291 Ran protein signal transduction(GO:0031291)
0.2 1.5 GO:0015793 glycerol transport(GO:0015793)
0.2 1.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 1.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.9 GO:0032571 response to vitamin K(GO:0032571)
0.2 0.8 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 1.5 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.2 0.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.9 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.2 1.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 3.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.2 0.3 GO:0048534 immune system development(GO:0002520) hemopoiesis(GO:0030097) hematopoietic or lymphoid organ development(GO:0048534)
0.2 0.5 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.2 1.4 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.2 0.9 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.2 1.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 0.8 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.2 1.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.5 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.2 0.5 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.2 4.0 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.2 0.2 GO:0015865 purine nucleotide transport(GO:0015865)
0.2 0.9 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.2 0.3 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.2 0.9 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.8 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.9 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.6 GO:0036292 DNA rewinding(GO:0036292)
0.1 1.4 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.6 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.1 1.6 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.7 GO:0030070 insulin processing(GO:0030070)
0.1 1.7 GO:0019532 oxalate transport(GO:0019532)
0.1 1.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 8.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.5 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.8 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 1.8 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.8 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.4 GO:0043686 co-translational protein modification(GO:0043686)
0.1 1.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.4 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.1 1.0 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 3.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.8 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 1.8 GO:0000050 urea cycle(GO:0000050)
0.1 1.0 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 15.4 GO:0070268 cornification(GO:0070268)
0.1 1.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.3 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.6 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.3 GO:1903625 L-ascorbic acid biosynthetic process(GO:0019853) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 1.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.8 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 1.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.5 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 1.5 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.4 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 1.3 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.4 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.1 2.0 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.7 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.5 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 1.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 1.0 GO:0032364 oxygen homeostasis(GO:0032364)
0.1 1.1 GO:0032790 ribosome disassembly(GO:0032790)
0.1 1.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 7.3 GO:0030574 collagen catabolic process(GO:0030574)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 1.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.9 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 1.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.2 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 0.6 GO:0003383 apical constriction(GO:0003383)
0.1 0.8 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.6 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.0 GO:0009642 response to light intensity(GO:0009642)
0.1 0.3 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.2 GO:0038188 cholecystokinin signaling pathway(GO:0038188)
0.1 0.3 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 2.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.7 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.1 4.3 GO:0031424 keratinization(GO:0031424)
0.1 1.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.3 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 1.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 0.1 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 1.0 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.2 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.2 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.2 GO:0031346 positive regulation of cell projection organization(GO:0031346)
0.1 0.4 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 4.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 1.2 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.5 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 1.3 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.2 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 1.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.5 GO:0030033 microvillus assembly(GO:0030033)
0.1 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 1.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 1.7 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.9 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 0.6 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 0.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 1.5 GO:0006907 pinocytosis(GO:0006907)
0.1 0.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.4 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 4.1 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 0.2 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.1 1.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.4 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.1 0.3 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 1.3 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 1.2 GO:0001556 oocyte maturation(GO:0001556)
0.1 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 2.2 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 0.3 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.3 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 1.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 3.5 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 1.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 1.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0048840 otolith development(GO:0048840)
0.0 0.3 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 2.2 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.5 GO:0033005 positive regulation of mast cell activation(GO:0033005) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.4 GO:2000172 endoplasmic reticulum tubular network assembly(GO:0071787) regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.3 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 1.3 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 1.0 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.8 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.5 GO:0008228 opsonization(GO:0008228)
0.0 0.3 GO:2000507 cap-dependent translational initiation(GO:0002191) positive regulation of energy homeostasis(GO:2000507)
0.0 2.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.3 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 3.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 2.0 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.3 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 2.0 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 1.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.5 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.3 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 2.4 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 1.1 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.0 0.4 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.4 GO:0051294 establishment of spindle orientation(GO:0051294)
0.0 0.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0010453 regulation of cell fate commitment(GO:0010453)
0.0 0.2 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.5 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0030728 ovulation(GO:0030728)
0.0 0.0 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.3 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 1.2 GO:0007588 excretion(GO:0007588)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 3.1 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 2.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 3.7 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 4.6 GO:0007565 female pregnancy(GO:0007565)
0.0 0.6 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 1.5 GO:0006970 response to osmotic stress(GO:0006970)
0.0 1.6 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.6 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.7 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:0072126 positive regulation of glomerular mesangial cell proliferation(GO:0072126)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.4 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.6 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.6 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0007628 adult walking behavior(GO:0007628)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0006825 copper ion transport(GO:0006825)
0.0 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 2.5 GO:0009408 response to heat(GO:0009408)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.6 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 1.0 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 1.3 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.4 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091) metaphase/anaphase transition of cell cycle(GO:0044784)
0.0 0.9 GO:0032259 methylation(GO:0032259)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.0 GO:0051225 spindle assembly(GO:0051225)
0.0 0.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 8.1 GO:0005610 laminin-5 complex(GO:0005610)
0.9 2.8 GO:0031523 Myb complex(GO:0031523)
0.8 3.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.6 8.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.5 2.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.4 1.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.3 2.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 1.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 2.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 2.9 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 0.8 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 1.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.2 0.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 0.5 GO:0002139 stereocilia coupling link(GO:0002139)
0.2 0.5 GO:0097447 dendritic tree(GO:0097447)
0.2 2.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 3.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.1 2.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 4.8 GO:0030057 desmosome(GO:0030057)
0.1 3.7 GO:0071437 invadopodium(GO:0071437)
0.1 0.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 2.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.9 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 1.8 GO:0008091 spectrin(GO:0008091)
0.1 1.8 GO:0035102 PRC1 complex(GO:0035102)
0.1 2.3 GO:0032433 filopodium tip(GO:0032433)
0.1 3.5 GO:0097228 sperm principal piece(GO:0097228)
0.1 0.5 GO:0044305 calyx of Held(GO:0044305)
0.1 3.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 0.5 GO:1990357 terminal web(GO:1990357)
0.1 1.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 1.4 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.2 GO:0035841 new growing cell tip(GO:0035841)
0.1 0.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 11.9 GO:0005882 intermediate filament(GO:0005882)
0.1 1.7 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.8 GO:0070187 telosome(GO:0070187)
0.1 3.0 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 0.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.5 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.8 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.6 GO:0036020 endolysosome membrane(GO:0036020)
0.1 3.4 GO:0031941 filamentous actin(GO:0031941)
0.1 1.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.5 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.7 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 1.9 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 4.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.5 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.4 GO:0030897 HOPS complex(GO:0030897)
0.0 3.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.8 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 1.2 GO:0030018 Z disc(GO:0030018)
0.0 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 1.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 2.0 GO:0005771 multivesicular body(GO:0005771)
0.0 0.5 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 19.4 GO:0005925 focal adhesion(GO:0005925)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.1 GO:0005901 caveola(GO:0005901)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 4.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 2.9 GO:0035579 specific granule membrane(GO:0035579)
0.0 2.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.1 GO:0043296 apical junction complex(GO:0043296)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 1.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 3.4 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.9 GO:0005884 actin filament(GO:0005884)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.0 GO:0031514 motile cilium(GO:0031514)
0.0 0.4 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 2.3 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.3 GO:0099738 cell cortex region(GO:0099738)
0.0 1.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.9 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.8 2.4 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.8 3.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.7 2.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.6 3.8 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.6 3.6 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.5 1.5 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.5 1.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.5 7.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 1.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 1.0 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.3 1.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.3 1.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.3 3.4 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.3 1.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.3 0.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 4.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 1.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.2 1.0 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.2 1.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.2 1.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.2 2.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 1.1 GO:0050436 microfibril binding(GO:0050436)
0.2 1.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.2 1.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.8 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 1.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 0.8 GO:0004461 lactose synthase activity(GO:0004461)
0.2 2.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 1.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.5 GO:0004111 creatine kinase activity(GO:0004111)
0.2 0.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 1.8 GO:0042731 PH domain binding(GO:0042731)
0.2 0.9 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 0.8 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 0.5 GO:0070052 collagen V binding(GO:0070052)
0.2 0.5 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.2 3.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 0.9 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.2 1.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.4 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 1.0 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.4 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 1.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 3.4 GO:0031005 filamin binding(GO:0031005)
0.1 4.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.4 GO:0070984 SET domain binding(GO:0070984)
0.1 1.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.8 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 3.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.9 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 2.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.8 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 3.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.3 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 13.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.7 GO:0032190 acrosin binding(GO:0032190)
0.1 1.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.6 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.3 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 1.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 2.0 GO:0017166 vinculin binding(GO:0017166)
0.1 0.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.3 GO:1903135 cupric ion binding(GO:1903135)
0.1 1.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.7 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.2 GO:0004951 cholecystokinin receptor activity(GO:0004951)
0.1 1.4 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.4 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 1.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.2 GO:0015563 thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.1 0.6 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.1 1.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 1.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 3.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 2.6 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.4 GO:1990405 protein antigen binding(GO:1990405)
0.1 0.3 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 3.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.5 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 1.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.9 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 4.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 4.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 1.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 1.1 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0044388 ubiquitin activating enzyme activity(GO:0004839) small protein activating enzyme binding(GO:0044388)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.8 GO:0004872 receptor activity(GO:0004872) molecular transducer activity(GO:0060089)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 2.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.5 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 1.9 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 6.6 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 2.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.9 GO:0051117 ATPase binding(GO:0051117)
0.0 2.0 GO:0051087 chaperone binding(GO:0051087)
0.0 1.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 2.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 4.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 1.5 GO:0051015 actin filament binding(GO:0051015)
0.0 4.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 4.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 7.8 GO:0005198 structural molecule activity(GO:0005198)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.1 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 11.9 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.1 4.1 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 3.0 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.1 1.3 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.1 2.5 PID_GMCSF_PATHWAY GMCSF-mediated signaling events
0.1 3.8 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.1 3.5 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.2 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.1 0.7 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 3.3 PID_WNT_NONCANONICAL_PATHWAY Noncanonical Wnt signaling pathway
0.1 2.2 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.8 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.1 5.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 0.8 PID_ALK2_PATHWAY ALK2 signaling events
0.1 1.7 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 6.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.5 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.8 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.9 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.5 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.4 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 2.0 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.0 1.1 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 2.5 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.3 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.8 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.5 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID_TCPTP_PATHWAY Signaling events mediated by TCPTP
0.0 1.0 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.4 PID_TGFBR_PATHWAY TGF-beta receptor signaling
0.0 0.7 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 1.3 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.7 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID_AVB3_INTEGRIN_PATHWAY Integrins in angiogenesis
0.0 0.3 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.9 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.4 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 1.3 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 1.0 PID_CD8_TCR_DOWNSTREAM_PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.9 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.8 PID_TELOMERASE_PATHWAY Regulation of Telomerase
0.0 0.9 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.2 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID_P38_ALPHA_BETA_DOWNSTREAM_PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.8 PID_P53_DOWNSTREAM_PATHWAY Direct p53 effectors
0.0 1.2 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 0.0 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.4 PID_CXCR4_PATHWAY CXCR4-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.9 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 4.1 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.3 4.8 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 3.1 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.2 4.2 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 4.1 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.2 11.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.4 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.1 4.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.6 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 3.9 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 4.5 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 3.6 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 4.0 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.6 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.1 2.9 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 9.3 REACTOME_CELL_JUNCTION_ORGANIZATION Genes involved in Cell junction organization
0.1 1.3 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.1 3.5 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.3 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 1.7 REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 0.7 REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.8 REACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.3 REACTOME_CTLA4_INHIBITORY_SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 1.4 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.0 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.0 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.1 1.6 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.1 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.2 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.1 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.1 3.2 REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.5 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 1.0 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.9 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 2.9 REACTOME_SMOOTH_MUSCLE_CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 2.0 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.4 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 1.3 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.0 3.2 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.8 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.2 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.9 REACTOME_SIGNALING_BY_NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.7 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.7 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.7 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 2.8 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.7 REACTOME_INTERFERON_GAMMA_SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.3 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.8 REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.8 REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.8 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.6 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.9 REACTOME_SIGNALING_BY_SCF_KIT Genes involved in Signaling by SCF-KIT
0.0 0.3 REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_2_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.3 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 1.1 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo