Motif ID: ATF6
Z-value: 0.616
Transcription factors associated with ATF6:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
ATF6 | ENSG00000118217.5 | ATF6 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
ATF6 | hg19_v2_chr1_+_161736072_161736093 | -0.19 | 3.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.6 | GO:0010734 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
0.2 | 0.8 | GO:0060830 | intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
0.2 | 0.5 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) |
0.1 | 0.3 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
0.1 | 0.2 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
0.1 | 0.2 | GO:1902310 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
0.1 | 0.2 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
0.1 | 0.2 | GO:0061054 | dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) |
0.1 | 0.2 | GO:0007343 | egg activation(GO:0007343) |
0.0 | 0.2 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
0.0 | 0.5 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
0.0 | 1.0 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
0.0 | 0.2 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
0.0 | 0.1 | GO:0032223 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
0.0 | 0.2 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.0 | 0.1 | GO:1903860 | negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173) |
0.0 | 0.1 | GO:0090156 | cellular sphingolipid homeostasis(GO:0090156) |
0.0 | 0.1 | GO:0042450 | arginine biosynthetic process via ornithine(GO:0042450) |
0.0 | 0.1 | GO:0034059 | response to anoxia(GO:0034059) |
0.0 | 0.1 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
0.0 | 0.2 | GO:0050916 | sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917) |
0.0 | 0.1 | GO:0039019 | regulation of polarized epithelial cell differentiation(GO:0030860) pronephric nephron development(GO:0039019) |
0.0 | 0.2 | GO:0044208 | 'de novo' AMP biosynthetic process(GO:0044208) |
0.0 | 0.2 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
0.0 | 0.1 | GO:0035610 | protein side chain deglutamylation(GO:0035610) |
0.0 | 0.1 | GO:0097212 | cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824) |
0.0 | 0.1 | GO:0021553 | olfactory nerve development(GO:0021553) |
0.0 | 0.0 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
0.0 | 0.1 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) |
0.0 | 0.3 | GO:0001561 | fatty acid alpha-oxidation(GO:0001561) |
0.0 | 0.3 | GO:0002115 | store-operated calcium entry(GO:0002115) |
0.0 | 0.2 | GO:0032025 | response to cobalt ion(GO:0032025) |
0.0 | 0.1 | GO:0002669 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519) |
0.0 | 0.2 | GO:0042908 | xenobiotic transport(GO:0042908) |
0.0 | 0.1 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
0.0 | 0.2 | GO:0061525 | hindgut development(GO:0061525) |
0.0 | 0.4 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
0.0 | 0.0 | GO:1903895 | negative regulation of IRE1-mediated unfolded protein response(GO:1903895) |
0.0 | 0.1 | GO:0052055 | modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) negative regulation by host of symbiont molecular function(GO:0052405) modulation by host of symbiont catalytic activity(GO:0052422) |
0.0 | 0.1 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
0.0 | 0.0 | GO:0061188 | negative regulation of chromatin silencing at rDNA(GO:0061188) |
0.0 | 0.1 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
0.0 | 0.2 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
0.0 | 0.1 | GO:0071907 | determination of digestive tract left/right asymmetry(GO:0071907) |
0.0 | 0.1 | GO:0006620 | posttranslational protein targeting to membrane(GO:0006620) |
0.0 | 0.2 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
0.0 | 0.1 | GO:0072086 | specification of loop of Henle identity(GO:0072086) |
0.0 | 0.1 | GO:0048733 | sebaceous gland development(GO:0048733) |
0.0 | 0.1 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
0.0 | 0.3 | GO:0034587 | piRNA metabolic process(GO:0034587) |
0.0 | 0.0 | GO:1990180 | mitochondrial tRNA 3'-end processing(GO:1990180) |
0.0 | 0.1 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
0.0 | 0.1 | GO:0021784 | postganglionic parasympathetic fiber development(GO:0021784) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) |
0.0 | 0.1 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.0 | 0.2 | GO:0045475 | locomotor rhythm(GO:0045475) |
0.0 | 0.1 | GO:0044806 | G-quadruplex DNA unwinding(GO:0044806) |
0.0 | 0.0 | GO:0006864 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
0.0 | 0.1 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.0 | 0.0 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
0.0 | 0.1 | GO:0060235 | lens induction in camera-type eye(GO:0060235) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.3 | GO:0030849 | autosome(GO:0030849) |
0.1 | 0.8 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
0.1 | 0.2 | GO:0097598 | sperm cytoplasmic droplet(GO:0097598) |
0.1 | 1.6 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.1 | 0.2 | GO:0043293 | apoptosome(GO:0043293) |
0.1 | 0.2 | GO:0033011 | perinuclear theca(GO:0033011) |
0.0 | 0.4 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.1 | GO:0035339 | SPOTS complex(GO:0035339) |
0.0 | 0.1 | GO:0032798 | Swi5-Sfr1 complex(GO:0032798) |
0.0 | 0.2 | GO:0005827 | polar microtubule(GO:0005827) |
0.0 | 0.1 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
0.0 | 0.3 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
0.0 | 0.1 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
0.0 | 0.0 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
0.0 | 0.1 | GO:0016589 | NURF complex(GO:0016589) |
0.0 | 0.1 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
0.0 | 0.2 | GO:0036020 | endolysosome membrane(GO:0036020) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.0 | GO:0048039 | ubiquinone binding(GO:0048039) |
0.1 | 0.3 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
0.1 | 0.5 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
0.1 | 0.2 | GO:0004019 | adenylosuccinate synthase activity(GO:0004019) |
0.1 | 0.2 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.0 | 0.7 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.0 | 0.2 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) |
0.0 | 0.4 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.0 | 0.2 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
0.0 | 0.1 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
0.0 | 0.1 | GO:0052810 | 1-phosphatidylinositol-5-kinase activity(GO:0052810) |
0.0 | 0.1 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
0.0 | 0.2 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) |
0.0 | 0.2 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
0.0 | 0.1 | GO:0034353 | RNA pyrophosphohydrolase activity(GO:0034353) |
0.0 | 1.5 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
0.0 | 0.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.1 | GO:1990460 | leptin receptor binding(GO:1990460) |
0.0 | 0.2 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
0.0 | 0.1 | GO:0008263 | pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
0.0 | 1.0 | GO:0050699 | WW domain binding(GO:0050699) |
0.0 | 0.1 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
0.0 | 0.2 | GO:0015926 | glucosidase activity(GO:0015926) |
0.0 | 0.2 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
0.0 | 0.1 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.0 | 0.1 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.0 | 0.1 | GO:0016842 | amidine-lyase activity(GO:0016842) |
0.0 | 0.1 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.0 | 0.2 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
0.0 | 0.1 | GO:0052836 | inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
0.0 | 0.0 | GO:0005046 | KDEL sequence binding(GO:0005046) |
0.0 | 0.1 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.0 | 0.1 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.0 | 0.1 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.0 | 0.0 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
0.0 | 0.1 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.7 | PID_TCR_CALCIUM_PATHWAY | Calcium signaling in the CD4+ TCR pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.4 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.2 | REACTOME_COPI_MEDIATED_TRANSPORT | Genes involved in COPI Mediated Transport |
0.0 | 0.4 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
0.0 | 0.4 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
0.0 | 0.1 | REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
0.0 | 0.2 | REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
0.0 | 0.2 | REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle |