Motif ID: ATF6

Z-value: 0.616


Transcription factors associated with ATF6:

Gene SymbolEntrez IDGene Name
ATF6 ENSG00000118217.5 ATF6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ATF6hg19_v2_chr1_+_161736072_161736093-0.193.8e-01Click!


Activity profile for motif ATF6.

activity profile for motif ATF6


Sorted Z-values histogram for motif ATF6

Sorted Z-values for motif ATF6



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_35630926 0.792 ENST00000588081.1
ENST00000589121.1
FXYD1

FXYD domain containing ion transport regulator 1

chr19_+_35630628 0.779 ENST00000588715.1
ENST00000588607.1
FXYD1

FXYD domain containing ion transport regulator 1

chrX_-_100914781 0.598 ENST00000431597.1
ENST00000458024.1
ENST00000413506.1
ENST00000440675.1
ENST00000328766.5
ENST00000356824.4
ARMCX2





armadillo repeat containing, X-linked 2





chr10_-_118032979 0.550 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr12_+_56661033 0.512 ENST00000433805.2
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr12_+_56660633 0.468 ENST00000308197.5
COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr7_-_19157248 0.464 ENST00000242261.5
TWIST1
twist family bHLH transcription factor 1
chr3_+_129158926 0.420 ENST00000347300.2
ENST00000296266.3
IFT122

intraflagellar transport 122 homolog (Chlamydomonas)

chrX_-_101397433 0.408 ENST00000372774.3
TCEAL6
transcription elongation factor A (SII)-like 6
chr3_+_129159039 0.405 ENST00000507564.1
ENST00000431818.2
ENST00000504021.1
ENST00000349441.2
ENST00000348417.2
ENST00000440957.2
IFT122





intraflagellar transport 122 homolog (Chlamydomonas)





chr14_+_65016620 0.404 ENST00000298705.1
PPP1R36
protein phosphatase 1, regulatory subunit 36
chr15_+_72947079 0.400 ENST00000421285.3
GOLGA6B
golgin A6 family, member B
chr7_+_102073966 0.339 ENST00000495936.1
ENST00000356387.2
ENST00000478730.2
ENST00000468241.1
ENST00000403646.3
ORAI2




ORAI calcium release-activated calcium modulator 2




chr16_-_66959429 0.332 ENST00000420652.1
ENST00000299759.6
RRAD

Ras-related associated with diabetes

chr9_+_100000717 0.320 ENST00000375205.2
ENST00000357054.1
ENST00000395220.1
ENST00000375202.2
ENST00000411667.2
CCDC180




coiled-coil domain containing 180




chr3_+_184053703 0.319 ENST00000450976.1
ENST00000418281.1
ENST00000340957.5
ENST00000433578.1
FAM131A



family with sequence similarity 131, member A



chr10_+_22634384 0.300 ENST00000376624.3
ENST00000376603.2
ENST00000376601.1
ENST00000538630.1
ENST00000456231.2
ENST00000313311.6
ENST00000435326.1
SPAG6






sperm associated antigen 6






chr3_+_100211412 0.294 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A


transmembrane protein 45A


chr7_-_98467629 0.290 ENST00000339375.4
TMEM130
transmembrane protein 130
chr9_-_79520989 0.286 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2


prune homolog 2 (Drosophila)


chr7_-_98467489 0.285 ENST00000416379.2
TMEM130
transmembrane protein 130
chr7_-_98467543 0.281 ENST00000345589.4
TMEM130
transmembrane protein 130
chr2_-_216946500 0.269 ENST00000265322.7
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr14_-_106092403 0.263 ENST00000390543.2
IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr6_+_159291090 0.262 ENST00000367073.4
ENST00000608817.1
C6orf99

chromosome 6 open reading frame 99

chr6_+_159290917 0.260 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chrX_+_102862834 0.259 ENST00000372627.5
ENST00000243286.3
TCEAL3

transcription elongation factor A (SII)-like 3

chr15_-_74374891 0.256 ENST00000290438.3
GOLGA6A
golgin A6 family, member A
chr17_+_6554971 0.250 ENST00000391428.2
C17orf100
chromosome 17 open reading frame 100
chr10_+_35415851 0.244 ENST00000374726.3
CREM
cAMP responsive element modulator
chr3_+_184056614 0.244 ENST00000453072.1
FAM131A
family with sequence similarity 131, member A
chrY_+_2803322 0.230 ENST00000383052.1
ENST00000155093.3
ENST00000449237.1
ENST00000443793.1
ZFY



zinc finger protein, Y-linked



chr17_-_66951474 0.228 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr2_-_74692473 0.228 ENST00000535045.1
ENST00000409065.1
ENST00000414701.1
ENST00000448666.1
ENST00000233616.4
ENST00000452063.2
MOGS





mannosyl-oligosaccharide glucosidase





chr2_-_47572105 0.221 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4



AC073283.4



chr4_-_24914576 0.221 ENST00000502801.1
ENST00000428116.2
CCDC149

coiled-coil domain containing 149

chr2_-_27712583 0.220 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
IFT172


intraflagellar transport 172 homolog (Chlamydomonas)


chr11_-_119234876 0.217 ENST00000525735.1
USP2
ubiquitin specific peptidase 2
chr12_+_117176113 0.207 ENST00000319176.7
RNFT2
ring finger protein, transmembrane 2
chr17_+_17876127 0.202 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48









leucine rich repeat containing 48









chr1_-_185126037 0.202 ENST00000367506.5
ENST00000367504.3
TRMT1L

tRNA methyltransferase 1 homolog (S. cerevisiae)-like

chr22_+_42394780 0.201 ENST00000328823.9
WBP2NL
WBP2 N-terminal like
chr22_-_31741757 0.199 ENST00000215919.3
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr5_+_78532003 0.199 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr5_+_63802109 0.199 ENST00000334025.2
RGS7BP
regulator of G-protein signaling 7 binding protein
chr19_+_49375649 0.189 ENST00000200453.5
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr8_-_38126675 0.189 ENST00000531823.1
ENST00000534339.1
ENST00000524616.1
ENST00000422581.2
ENST00000424479.2
ENST00000419686.2
PPAPDC1B





phosphatidic acid phosphatase type 2 domain containing 1B





chr11_+_61717842 0.186 ENST00000449131.2
BEST1
bestrophin 1
chr7_+_116593568 0.185 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr15_-_52030293 0.184 ENST00000560491.1
ENST00000267838.3
LYSMD2

LysM, putative peptidoglycan-binding, domain containing 2

chr1_-_151254362 0.184 ENST00000447795.2
RP11-126K1.2
Uncharacterized protein
chr10_-_105218645 0.170 ENST00000329905.5
CALHM1
calcium homeostasis modulator 1
chr7_+_30811004 0.168 ENST00000265299.6
FAM188B
family with sequence similarity 188, member B
chr17_-_57184260 0.168 ENST00000376149.3
ENST00000393066.3
TRIM37

tripartite motif containing 37

chr12_+_49372251 0.168 ENST00000293549.3
WNT1
wingless-type MMTV integration site family, member 1
chr14_+_105190514 0.166 ENST00000330877.2
ADSSL1
adenylosuccinate synthase like 1
chr15_+_75575176 0.163 ENST00000434739.3
GOLGA6D
golgin A6 family, member D
chr9_-_89562104 0.163 ENST00000298743.7
GAS1
growth arrest-specific 1
chr4_+_85504075 0.163 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr3_+_33318914 0.162 ENST00000484457.1
ENST00000538892.1
ENST00000538181.1
ENST00000446237.3
ENST00000507198.1
FBXL2




F-box and leucine-rich repeat protein 2




chr19_-_40724246 0.160 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr1_+_166958346 0.160 ENST00000367872.4
MAEL
maelstrom spermatogenic transposon silencer
chr18_+_56530794 0.155 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532


zinc finger protein 532


chr1_-_94050668 0.155 ENST00000539242.1
BCAR3
breast cancer anti-estrogen resistance 3
chr11_+_1891380 0.153 ENST00000429923.1
ENST00000418975.1
ENST00000406638.2
LSP1


lymphocyte-specific protein 1


chr10_+_35416090 0.153 ENST00000354759.3
CREM
cAMP responsive element modulator
chr5_+_94890778 0.153 ENST00000380009.4
ARSK
arylsulfatase family, member K
chr4_+_128982416 0.152 ENST00000326639.6
LARP1B
La ribonucleoprotein domain family, member 1B
chr8_-_38126635 0.151 ENST00000529359.1
PPAPDC1B
phosphatidic acid phosphatase type 2 domain containing 1B
chr1_-_32801825 0.150 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr9_+_114393581 0.146 ENST00000313525.3
DNAJC25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr22_-_20850128 0.146 ENST00000328879.4
KLHL22
kelch-like family member 22
chr2_+_219745020 0.145 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr21_-_38445011 0.142 ENST00000464265.1
ENST00000399102.1
PIGP

phosphatidylinositol glycan anchor biosynthesis, class P

chr20_+_35090150 0.138 ENST00000340491.4
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr7_+_116593433 0.137 ENST00000323984.3
ENST00000393449.1
ST7

suppression of tumorigenicity 7

chr1_+_166958497 0.136 ENST00000367870.2
MAEL
maelstrom spermatogenic transposon silencer
chr8_-_75233563 0.135 ENST00000342232.4
JPH1
junctophilin 1
chr19_+_6772710 0.132 ENST00000304076.2
ENST00000602142.1
ENST00000596764.1
VAV1


vav 1 guanine nucleotide exchange factor


chr10_+_35415719 0.131 ENST00000474362.1
ENST00000374721.3
CREM

cAMP responsive element modulator

chr2_-_211036051 0.126 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L


KAT8 regulatory NSL complex subunit 1-like


chrX_+_122318006 0.126 ENST00000371266.1
ENST00000264357.5
GRIA3

glutamate receptor, ionotropic, AMPA 3

chr17_+_42977122 0.122 ENST00000417826.2
ENST00000412523.2
ENST00000331733.4
CCDC103
FAM187A

coiled-coil domain containing 103
family with sequence similarity 187, member A

chr7_-_8302164 0.122 ENST00000447326.1
ENST00000406470.2
ICA1

islet cell autoantigen 1, 69kDa

chr7_-_8301682 0.121 ENST00000396675.3
ENST00000430867.1
ICA1

islet cell autoantigen 1, 69kDa

chr7_-_86849883 0.121 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr17_-_49337392 0.121 ENST00000376381.2
ENST00000586178.1
MBTD1

mbt domain containing 1

chr4_+_668348 0.120 ENST00000511290.1
MYL5
myosin, light chain 5, regulatory
chr7_-_100493744 0.120 ENST00000428317.1
ENST00000441605.1
ACHE

acetylcholinesterase (Yt blood group)

chr7_-_8301768 0.119 ENST00000265577.7
ICA1
islet cell autoantigen 1, 69kDa
chr13_+_53226963 0.118 ENST00000343788.6
ENST00000535397.1
ENST00000310528.8
SUGT1


SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)


chr11_+_47430133 0.118 ENST00000531974.1
ENST00000531419.1
ENST00000531865.1
ENST00000362021.4
ENST00000354884.4
SLC39A13




solute carrier family 39 (zinc transporter), member 13




chr21_-_38445470 0.117 ENST00000399098.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_-_8301869 0.117 ENST00000402384.3
ICA1
islet cell autoantigen 1, 69kDa
chr1_+_185126291 0.116 ENST00000367500.4
SWT1
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr17_+_33914460 0.116 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr2_+_216176761 0.115 ENST00000540518.1
ENST00000435675.1
ATIC

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

chr1_+_221051699 0.114 ENST00000366903.6
HLX
H2.0-like homeobox
chr17_+_33914276 0.114 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1



adaptor-related protein complex 2, beta 1 subunit



chr2_-_60780702 0.114 ENST00000359629.5
BCL11A
B-cell CLL/lymphoma 11A (zinc finger protein)
chr8_+_61429728 0.114 ENST00000529579.1
RAB2A
RAB2A, member RAS oncogene family
chr8_+_22422749 0.113 ENST00000523900.1
SORBS3
sorbin and SH3 domain containing 3
chr4_-_39640700 0.113 ENST00000295958.5
SMIM14
small integral membrane protein 14
chr1_-_15850676 0.113 ENST00000440484.1
ENST00000333868.5
CASP9

caspase 9, apoptosis-related cysteine peptidase

chrX_-_48433275 0.112 ENST00000376775.2
AC115618.1
Uncharacterized protein; cDNA FLJ26048 fis, clone PRS02384
chr2_-_190649082 0.112 ENST00000392350.3
ENST00000392349.4
ORMDL1

ORM1-like 1 (S. cerevisiae)

chr6_+_33168637 0.111 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr10_+_35415978 0.111 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
CREM


cAMP responsive element modulator


chr2_+_216176540 0.110 ENST00000236959.9
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr1_-_15850839 0.109 ENST00000348549.5
ENST00000546424.1
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr13_-_36920615 0.109 ENST00000494062.2
SPG20
spastic paraplegia 20 (Troyer syndrome)
chr11_-_33183048 0.109 ENST00000438862.2
CSTF3
cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
chr16_+_22217577 0.108 ENST00000263026.5
EEF2K
eukaryotic elongation factor-2 kinase
chr5_+_56469843 0.107 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr4_-_119757239 0.106 ENST00000280551.6
SEC24D
SEC24 family member D
chr14_+_76776957 0.105 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr14_-_106068065 0.105 ENST00000390541.2
IGHE
immunoglobulin heavy constant epsilon
chr6_+_33168597 0.105 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr2_-_242212227 0.105 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
HDLBP








high density lipoprotein binding protein








chr20_-_22559211 0.104 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr1_-_25573937 0.103 ENST00000417642.2
ENST00000431849.2
C1orf63

chromosome 1 open reading frame 63

chr12_+_7282795 0.102 ENST00000266546.6
CLSTN3
calsyntenin 3
chr7_+_16793160 0.102 ENST00000262067.4
TSPAN13
tetraspanin 13
chr6_-_135818844 0.101 ENST00000524469.1
ENST00000367800.4
ENST00000327035.6
ENST00000457866.2
ENST00000265602.6
AHI1




Abelson helper integration site 1




chr16_+_19125252 0.101 ENST00000566735.1
ENST00000381440.3
ITPRIPL2

inositol 1,4,5-trisphosphate receptor interacting protein-like 2

chr1_+_114472481 0.095 ENST00000369555.2
HIPK1
homeodomain interacting protein kinase 1
chr10_-_27444143 0.095 ENST00000477432.1
YME1L1
YME1-like 1 ATPase
chr7_+_100464760 0.093 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr9_+_131038425 0.092 ENST00000320188.5
ENST00000608796.1
ENST00000419867.2
ENST00000418976.1
SWI5



SWI5 recombination repair homolog (yeast)



chr5_+_122110691 0.092 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
SNX2


sorting nexin 2


chr17_+_65821636 0.092 ENST00000544778.2
BPTF
bromodomain PHD finger transcription factor
chr20_+_34042962 0.092 ENST00000446710.1
ENST00000420564.1
CEP250

centrosomal protein 250kDa

chr5_+_34656569 0.092 ENST00000428746.2
RAI14
retinoic acid induced 14
chr3_-_156877997 0.092 ENST00000295926.3
CCNL1
cyclin L1
chr12_-_56709674 0.090 ENST00000549318.1
ENST00000551286.1
RP11-977G19.10
CNPY2
Uncharacterized protein
canopy FGF signaling regulator 2
chr19_+_10527449 0.089 ENST00000592685.1
ENST00000380702.2
PDE4A

phosphodiesterase 4A, cAMP-specific

chr9_+_100818976 0.089 ENST00000210444.5
NANS
N-acetylneuraminic acid synthase
chr11_-_118927816 0.089 ENST00000534233.1
ENST00000532752.1
ENST00000525859.1
ENST00000404233.3
ENST00000532421.1
ENST00000543287.1
ENST00000527310.2
ENST00000529972.1
HYOU1







hypoxia up-regulated 1







chr14_-_64970494 0.088 ENST00000608382.1
ZBTB25
zinc finger and BTB domain containing 25
chr3_-_195270162 0.088 ENST00000438848.1
ENST00000328432.3
PPP1R2

protein phosphatase 1, regulatory (inhibitor) subunit 2

chr17_-_15466742 0.088 ENST00000584811.1
ENST00000419890.2
TVP23C

trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)

chr16_+_19729586 0.087 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQCK


IQ motif containing K


chr1_-_25573977 0.087 ENST00000243189.7
C1orf63
chromosome 1 open reading frame 63
chr4_+_1873155 0.086 ENST00000507820.1
ENST00000514045.1
WHSC1

Wolf-Hirschhorn syndrome candidate 1

chr5_+_56469775 0.086 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr1_+_110527308 0.086 ENST00000369799.5
AHCYL1
adenosylhomocysteinase-like 1
chr5_+_34656331 0.086 ENST00000265109.3
RAI14
retinoic acid induced 14
chr6_+_31865552 0.085 ENST00000469372.1
ENST00000497706.1
C2

complement component 2

chr21_-_38445297 0.085 ENST00000430792.1
ENST00000399103.1
PIGP

phosphatidylinositol glycan anchor biosynthesis, class P

chr1_-_165325939 0.084 ENST00000342310.3
LMX1A
LIM homeobox transcription factor 1, alpha
chr17_+_27071002 0.083 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TRAF4



TNF receptor-associated factor 4



chr11_-_35547151 0.082 ENST00000378878.3
ENST00000529303.1
ENST00000278360.3
PAMR1


peptidase domain containing associated with muscle regeneration 1


chr19_-_48673580 0.082 ENST00000427526.2
LIG1
ligase I, DNA, ATP-dependent
chr10_+_35416223 0.081 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM





cAMP responsive element modulator





chr6_+_116692102 0.079 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr11_-_35547572 0.079 ENST00000378880.2
PAMR1
peptidase domain containing associated with muscle regeneration 1
chr14_+_55518349 0.079 ENST00000395468.4
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr9_+_36036430 0.078 ENST00000377966.3
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr11_-_113746277 0.078 ENST00000003302.4
ENST00000545540.1
USP28

ubiquitin specific peptidase 28

chr4_-_39640513 0.077 ENST00000511809.1
ENST00000505729.1
SMIM14

small integral membrane protein 14

chr20_-_62738524 0.076 ENST00000369768.1
NPBWR2
neuropeptides B/W receptor 2
chr5_-_37839782 0.076 ENST00000326524.2
ENST00000515058.1
GDNF

glial cell derived neurotrophic factor

chr15_+_41913690 0.075 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr18_-_46987000 0.074 ENST00000442713.2
ENST00000269445.6
DYM

dymeclin

chr15_-_43785303 0.074 ENST00000382039.3
ENST00000450115.2
ENST00000382044.4
TP53BP1


tumor protein p53 binding protein 1


chr21_-_38445443 0.073 ENST00000360525.4
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr9_-_88356733 0.073 ENST00000376083.3
AGTPBP1
ATP/GTP binding protein 1
chr11_-_14521379 0.072 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
COPB1



coatomer protein complex, subunit beta 1



chr3_+_169684553 0.070 ENST00000337002.4
ENST00000480708.1
SEC62

SEC62 homolog (S. cerevisiae)

chr19_-_48673552 0.070 ENST00000536218.1
ENST00000596549.1
LIG1

ligase I, DNA, ATP-dependent

chr6_-_31938700 0.070 ENST00000495340.1
DXO
decapping exoribonuclease
chrX_+_122318113 0.070 ENST00000371264.3
GRIA3
glutamate receptor, ionotropic, AMPA 3
chr4_+_108745711 0.068 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr1_+_156830607 0.068 ENST00000368196.3
NTRK1
neurotrophic tyrosine kinase, receptor, type 1
chr6_+_127587755 0.068 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
RNF146





ring finger protein 146





chr9_-_77643189 0.066 ENST00000376837.3
C9orf41
chromosome 9 open reading frame 41
chr8_+_61429416 0.066 ENST00000262646.7
ENST00000531289.1
RAB2A

RAB2A, member RAS oncogene family

chr19_-_6502304 0.066 ENST00000540257.1
ENST00000594276.1
ENST00000594075.1
ENST00000600216.1
ENST00000596926.1
TUBB4A




tubulin, beta 4A class IVa




chr16_-_86588627 0.065 ENST00000565482.1
ENST00000564364.1
ENST00000561989.1
ENST00000543303.2
ENST00000381214.5
ENST00000360900.6
ENST00000322911.6
ENST00000546093.1
ENST00000569000.1
ENST00000562994.1
ENST00000561522.1
MTHFSD










methenyltetrahydrofolate synthetase domain containing










chr17_-_57184064 0.065 ENST00000262294.7
TRIM37
tripartite motif containing 37
chr12_+_57610562 0.065 ENST00000349394.5
NXPH4
neurexophilin 4
chr6_+_127588020 0.065 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
RNF146




ring finger protein 146




chr1_+_55271736 0.064 ENST00000358193.3
ENST00000371273.3
C1orf177

chromosome 1 open reading frame 177

chr21_+_38445539 0.063 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3





tetratricopeptide repeat domain 3





chr17_+_80693427 0.063 ENST00000300784.7
FN3K
fructosamine 3 kinase
chr15_-_82641706 0.063 ENST00000439287.4
GOLGA6L10
golgin A6 family-like 10
chr4_-_54930790 0.063 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr14_-_23822080 0.061 ENST00000397267.1
ENST00000354772.3
SLC22A17

solute carrier family 22, member 17

chr1_+_156830678 0.061 ENST00000524377.1
ENST00000358660.3
NTRK1

neurotrophic tyrosine kinase, receptor, type 1

chr6_-_31864977 0.060 ENST00000395728.3
ENST00000375528.4
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr16_-_54320675 0.060 ENST00000329734.3
IRX3
iroquois homeobox 3
chr9_-_88356789 0.060 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
AGTPBP1



ATP/GTP binding protein 1



chr17_+_18684563 0.060 ENST00000476139.1
TVP23B
trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
chr10_-_74856608 0.059 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1





prolyl 4-hydroxylase, alpha polypeptide I





chr7_-_26240357 0.059 ENST00000354667.4
ENST00000356674.7
HNRNPA2B1

heterogeneous nuclear ribonucleoprotein A2/B1

chr20_+_32951041 0.058 ENST00000374864.4
ITCH
itchy E3 ubiquitin protein ligase
chr17_+_57642886 0.057 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40




DEAH (Asp-Glu-Ala-His) box polypeptide 40




chr12_-_49463753 0.057 ENST00000301068.6
RHEBL1
Ras homolog enriched in brain like 1
chr1_+_87794150 0.057 ENST00000370544.5
LMO4
LIM domain only 4
chr7_+_65540853 0.057 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL



argininosuccinate lyase




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.2 0.8 GO:0060830 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.2 0.5 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.2 GO:1902310 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.2 GO:0061054 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.1 0.2 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.5 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 1.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:1903860 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0039019 regulation of polarized epithelial cell differentiation(GO:0030860) pronephric nephron development(GO:0039019)
0.0 0.2 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.2 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.1 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0061525 hindgut development(GO:0061525)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.0 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.1 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) negative regulation by host of symbiont molecular function(GO:0052405) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.0 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.1 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.0 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.1 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.0 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030849 autosome(GO:0030849)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 1.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.2 GO:0043293 apoptosome(GO:0043293)
0.1 0.2 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.0 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0036020 endolysosome membrane(GO:0036020)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.3 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.5 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.2 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.0 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle