Motif ID: ARID3A

Z-value: 0.534


Transcription factors associated with ARID3A:

Gene SymbolEntrez IDGene Name
ARID3A ENSG00000116017.6 ARID3A

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ARID3Ahg19_v2_chr19_+_926000_926046-0.174.3e-01Click!


Activity profile for motif ARID3A.

activity profile for motif ARID3A


Sorted Z-values histogram for motif ARID3A

Sorted Z-values for motif ARID3A



Network of associatons between targets according to the STRING database.



First level regulatory network of ARID3A

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_39759794 1.043 ENST00000518804.1
ENST00000519154.1
ENST00000522495.1
ENST00000522840.1
 IDO1



indoleamine 2,3-dioxygenase 1



chr16_+_19421803 0.927 ENST00000541464.1
 TMC5
transmembrane channel-like 5
chr9_-_27005686 0.841 ENST00000380055.5
 LRRC19
leucine rich repeat containing 19
chr16_-_21289627 0.770 ENST00000396023.2
ENST00000415987.2
 CRYM

crystallin, mu

chr4_+_69962212 0.723 ENST00000508661.1
 UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr4_+_69962185 0.721 ENST00000305231.7
 UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr16_+_19422035 0.679 ENST00000381414.4
ENST00000396229.2
 TMC5

transmembrane channel-like 5

chr12_-_71182695 0.566 ENST00000342084.4
 PTPRR
protein tyrosine phosphatase, receptor type, R
chr19_+_49199209 0.560 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
 FUT2


fucosyltransferase 2 (secretor status included)


chr7_+_6617039 0.504 ENST00000405731.3
ENST00000396713.2
ENST00000396707.2
ENST00000335965.6
ENST00000396709.1
ENST00000483589.1
ENST00000396706.2
 ZDHHC4






zinc finger, DHHC-type containing 4






chr4_-_110723194 0.494 ENST00000394635.3
 CFI
complement factor I
chr6_-_46703430 0.477 ENST00000537365.1
 PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr5_+_140220769 0.471 ENST00000531613.1
ENST00000378123.3
 PCDHA8

protocadherin alpha 8

chr6_+_47624172 0.464 ENST00000507065.1
ENST00000296862.1
 GPR111

G protein-coupled receptor 111

chr4_-_110723335 0.397 ENST00000394634.2
 CFI
complement factor I
chr1_+_77333117 0.390 ENST00000477717.1
 ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr6_+_27791862 0.384 ENST00000355057.1
 HIST1H4J
histone cluster 1, H4j
chr1_-_227505289 0.363 ENST00000366765.3
 CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr12_+_133757995 0.355 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
 ZNF268









zinc finger protein 268









chr12_+_133758115 0.341 ENST00000541009.2
ENST00000592241.1
 ZNF268

zinc finger protein 268


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 60 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 1.0 GO:0036269 swimming behavior(GO:0036269)
0.3 0.8 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.1 0.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 0.7 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 0.6 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.6 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 0.5 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.5 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566)
0.1 0.4 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.3 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.3 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.5 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.4 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0043159 cytoskeletal calyx(GO:0033150) acrosomal matrix(GO:0043159)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.3 1.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.2 0.8 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.8 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.6 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.4 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.4 GO:0070026 nitric oxide binding(GO:0070026)
0.1 0.4 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.3 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.2 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.0 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 0.5 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.3 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors