Motif ID: ALX3

Z-value: 0.605


Transcription factors associated with ALX3:

Gene SymbolEntrez IDGene Name
ALX3 ENSG00000156150.6 ALX3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ALX3hg19_v2_chr1_-_110613276_110613322-0.341.1e-01Click!


Activity profile for motif ALX3.

activity profile for motif ALX3


Sorted Z-values histogram for motif ALX3

Sorted Z-values for motif ALX3



Network of associatons between targets according to the STRING database.



First level regulatory network of ALX3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_25348007 2.702 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1






cancer susceptibility candidate 1






chr5_-_35938674 2.265 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
CAPSL



calcyphosine-like



chr11_+_101918153 2.244 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr12_+_7013897 2.098 ENST00000007969.8
ENST00000323702.5
LRRC23

leucine rich repeat containing 23

chr12_+_7014064 2.070 ENST00000443597.2
LRRC23
leucine rich repeat containing 23
chr11_-_63376013 1.606 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr12_-_10282836 1.576 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A


C-type lectin domain family 7, member A


chr16_-_55866997 1.496 ENST00000360526.3
ENST00000361503.4
CES1

carboxylesterase 1

chr12_+_7014126 1.454 ENST00000415834.1
ENST00000436789.1
LRRC23

leucine rich repeat containing 23

chr4_+_86525299 1.418 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr12_-_10282681 1.161 ENST00000533022.1
CLEC7A
C-type lectin domain family 7, member A
chr11_+_71900703 1.129 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr12_-_10282742 1.128 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A


C-type lectin domain family 7, member A


chr16_-_28634874 1.119 ENST00000395609.1
ENST00000350842.4
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr11_+_71900572 1.111 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr9_-_117111222 1.091 ENST00000374079.4
AKNA
AT-hook transcription factor
chr14_-_54423529 0.973 ENST00000245451.4
ENST00000559087.1
BMP4

bone morphogenetic protein 4

chr16_-_28608364 0.911 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr5_-_20575959 0.860 ENST00000507958.1
CDH18
cadherin 18, type 2
chr4_-_70518941 0.827 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1

UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus

UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr19_+_50016411 0.819 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT


Fc fragment of IgG, receptor, transporter, alpha


chr4_-_25865159 0.817 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr13_-_86373536 0.815 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr1_+_47533160 0.807 ENST00000334194.3
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr19_+_50016610 0.788 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr16_-_28621353 0.759 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr16_-_28608424 0.745 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr17_+_35851570 0.729 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr1_-_150738261 0.709 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr1_+_28261492 0.694 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr19_+_49199209 0.689 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2


fucosyltransferase 2 (secretor status included)


chr16_-_28621312 0.677 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr17_+_1674982 0.646 ENST00000572048.1
ENST00000573763.1
SERPINF1

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

chr1_+_28261621 0.645 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr16_-_28937027 0.615 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr9_+_90112767 0.599 ENST00000408954.3
DAPK1
death-associated protein kinase 1
chr8_+_105235572 0.595 ENST00000523362.1
RIMS2
regulating synaptic membrane exocytosis 2
chr14_+_74034310 0.555 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr16_-_28621298 0.529 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr9_+_90112590 0.515 ENST00000472284.1
DAPK1
death-associated protein kinase 1
chr9_+_90112741 0.509 ENST00000469640.2
DAPK1
death-associated protein kinase 1
chr7_+_48211048 0.502 ENST00000435803.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr9_+_90112117 0.482 ENST00000358077.5
DAPK1
death-associated protein kinase 1
chr4_-_138453559 0.464 ENST00000511115.1
PCDH18
protocadherin 18
chr11_+_100862811 0.460 ENST00000303130.2
TMEM133
transmembrane protein 133
chrX_+_77154935 0.455 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr3_+_140396881 0.438 ENST00000286349.3
TRIM42
tripartite motif containing 42
chr10_-_28571015 0.436 ENST00000375719.3
ENST00000375732.1
MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr6_+_26402465 0.434 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1





butyrophilin, subfamily 3, member A1





chr3_+_195447738 0.432 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20


mucin 20, cell surface associated


chr1_+_117544366 0.427 ENST00000256652.4
ENST00000369470.1
CD101

CD101 molecule

chr10_+_695888 0.423 ENST00000441152.2
PRR26
proline rich 26
chr4_+_37455536 0.420 ENST00000381980.4
ENST00000508175.1
C4orf19

chromosome 4 open reading frame 19

chr1_+_12976450 0.404 ENST00000361079.2
PRAMEF7
PRAME family member 7
chrX_+_130192318 0.386 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr5_-_96478466 0.371 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr2_+_217524323 0.370 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr6_+_26402517 0.369 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr13_+_78315295 0.368 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr12_+_131438443 0.365 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr5_+_140557371 0.356 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr6_+_26440700 0.352 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3









butyrophilin, subfamily 3, member A3









chr7_-_111032971 0.348 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr11_+_57480046 0.339 ENST00000378312.4
ENST00000278422.4
TMX2

thioredoxin-related transmembrane protein 2

chr16_+_31885079 0.333 ENST00000300870.10
ENST00000394846.3
ZNF267

zinc finger protein 267

chr13_+_24144796 0.331 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr19_+_42580274 0.330 ENST00000359044.4
ZNF574
zinc finger protein 574
chr22_-_32651326 0.325 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr8_-_102803163 0.316 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD






neurocalcin delta






chr11_-_128894053 0.291 ENST00000392657.3
ARHGAP32
Rho GTPase activating protein 32
chr10_+_91152303 0.284 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr18_-_53303123 0.283 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4


transcription factor 4


chr4_+_86699834 0.271 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr11_+_6897856 0.269 ENST00000379829.2
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr12_-_46121554 0.269 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr16_+_31724552 0.268 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720




zinc finger protein 720




chr1_-_54411240 0.266 ENST00000371378.2
HSPB11
heat shock protein family B (small), member 11
chr1_-_54411255 0.264 ENST00000371377.3
HSPB11
heat shock protein family B (small), member 11
chr1_+_225600404 0.261 ENST00000366845.2
AC092811.1
AC092811.1
chr5_-_94417339 0.260 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1


multiple C2 domains, transmembrane 1


chrX_+_36254051 0.257 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr1_+_160370344 0.246 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr14_-_78083112 0.239 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr7_+_133812052 0.236 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr4_-_66536196 0.235 ENST00000511294.1
EPHA5
EPH receptor A5
chr11_+_7618413 0.232 ENST00000528883.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_-_150669500 0.232 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr16_+_53133070 0.228 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr1_-_190446759 0.226 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr15_-_98417780 0.226 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr3_-_191000172 0.225 ENST00000427544.2
UTS2B
urotensin 2B
chr5_+_176811431 0.225 ENST00000512593.1
ENST00000324417.5
SLC34A1

solute carrier family 34 (type II sodium/phosphate contransporter), member 1

chr4_-_120243545 0.213 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr2_+_135596180 0.209 ENST00000283054.4
ENST00000392928.1
ACMSD

aminocarboxymuconate semialdehyde decarboxylase

chr15_-_89755034 0.201 ENST00000563254.1
RLBP1
retinaldehyde binding protein 1
chr17_-_4938712 0.199 ENST00000254853.5
ENST00000424747.1
SLC52A1

solute carrier family 52 (riboflavin transporter), member 1

chr7_-_43965937 0.197 ENST00000455877.1
ENST00000223341.7
ENST00000447717.3
ENST00000426198.1
URGCP



upregulator of cell proliferation



chr2_+_135596106 0.195 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chrX_-_13835147 0.194 ENST00000493677.1
ENST00000355135.2
GPM6B

glycoprotein M6B

chr6_+_52442083 0.193 ENST00000606714.1
TRAM2-AS1
TRAM2 antisense RNA 1 (head to head)
chr9_-_28670283 0.191 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr14_+_39736582 0.190 ENST00000556148.1
ENST00000348007.3
CTAGE5

CTAGE family, member 5

chr4_+_113568207 0.189 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr20_-_29978286 0.188 ENST00000376315.2
DEFB119
defensin, beta 119
chr12_+_66582919 0.186 ENST00000545837.1
ENST00000457197.2
IRAK3

interleukin-1 receptor-associated kinase 3

chr7_+_138145076 0.178 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr2_-_43266680 0.174 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2


AC016735.2


chr14_+_55493920 0.171 ENST00000395472.2
ENST00000555846.1
SOCS4

suppressor of cytokine signaling 4

chr15_+_44719970 0.169 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr16_-_66584059 0.169 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
TK2





thymidine kinase 2, mitochondrial





chr2_+_103089756 0.168 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr9_+_12775011 0.168 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr5_+_140762268 0.166 ENST00000518325.1
PCDHGA7
protocadherin gamma subfamily A, 7
chr2_-_152118352 0.165 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr19_+_47421933 0.162 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr14_+_55494323 0.158 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr7_-_92777606 0.158 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chr17_-_39191107 0.156 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr4_-_66536057 0.152 ENST00000273854.3
EPHA5
EPH receptor A5
chr3_+_138340049 0.150 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr3_+_45927994 0.149 ENST00000357632.2
ENST00000395963.2
CCR9

chemokine (C-C motif) receptor 9

chr15_-_75748115 0.147 ENST00000360439.4
SIN3A
SIN3 transcription regulator family member A
chr2_+_113299990 0.144 ENST00000537335.1
ENST00000417433.2
POLR1B

polymerase (RNA) I polypeptide B, 128kDa

chr9_-_5339873 0.142 ENST00000223862.1
ENST00000223858.4
RLN1

relaxin 1

chrX_-_21676442 0.138 ENST00000379499.2
KLHL34
kelch-like family member 34
chr15_-_37393406 0.132 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2


Meis homeobox 2


chr11_-_327537 0.131 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr1_-_24306768 0.129 ENST00000374453.3
ENST00000453840.3
SRSF10

serine/arginine-rich splicing factor 10

chr12_-_74686314 0.127 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2


RP11-81H3.2


chr11_+_92702886 0.125 ENST00000257068.2
ENST00000528076.1
MTNR1B

melatonin receptor 1B

chr6_-_36515177 0.124 ENST00000229812.7
STK38
serine/threonine kinase 38
chr1_-_150669604 0.121 ENST00000427665.1
ENST00000540514.1
GOLPH3L

golgi phosphoprotein 3-like

chr7_-_87856280 0.120 ENST00000490437.1
ENST00000431660.1
SRI

sorcin

chr2_+_234826016 0.119 ENST00000324695.4
ENST00000433712.2
TRPM8

transient receptor potential cation channel, subfamily M, member 8

chr22_-_40289759 0.118 ENST00000325157.6
ENTHD1
ENTH domain containing 1
chr8_-_116504448 0.117 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr3_+_138340067 0.117 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr9_+_105757590 0.114 ENST00000374798.3
ENST00000487798.1
CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chr8_+_107738240 0.114 ENST00000449762.2
ENST00000297447.6
OXR1

oxidation resistance 1

chr7_-_87856303 0.114 ENST00000394641.3
SRI
sorcin
chr19_-_44388116 0.111 ENST00000587539.1
ZNF404
zinc finger protein 404
chr20_-_43133491 0.111 ENST00000411544.1
SERINC3
serine incorporator 3
chr4_-_122686261 0.110 ENST00000337677.5
TMEM155
transmembrane protein 155
chr14_+_22977587 0.110 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chrX_-_138790348 0.109 ENST00000414978.1
ENST00000519895.1
MCF2

MCF.2 cell line derived transforming sequence

chr17_+_18086392 0.107 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr7_+_117864708 0.106 ENST00000357099.4
ENST00000265224.4
ENST00000486422.1
ENST00000417525.1
ANKRD7



ankyrin repeat domain 7



chr9_-_116065551 0.104 ENST00000297894.5
RNF183
ring finger protein 183
chr20_-_33735070 0.103 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2


ER degradation enhancer, mannosidase alpha-like 2


chr3_+_186353756 0.103 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB


fetuin B


chr12_-_122985067 0.100 ENST00000540586.1
ENST00000543897.1
ZCCHC8

zinc finger, CCHC domain containing 8

chr5_-_159846399 0.099 ENST00000297151.4
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr7_-_149158187 0.098 ENST00000247930.4
ZNF777
zinc finger protein 777
chr5_+_140201183 0.097 ENST00000529619.1
ENST00000529859.1
ENST00000378126.3
PCDHA5


protocadherin alpha 5


chr19_+_36139125 0.095 ENST00000246554.3
COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr11_-_13011081 0.095 ENST00000532541.1
ENST00000526388.1
ENST00000534477.1
ENST00000531402.1
ENST00000527945.1
ENST00000504230.2
LINC00958





long intergenic non-protein coding RNA 958





chr2_-_228497888 0.094 ENST00000264387.4
ENST00000409066.1
C2orf83

chromosome 2 open reading frame 83

chr2_-_220264703 0.090 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP



aspartyl aminopeptidase



chr11_+_5710919 0.089 ENST00000379965.3
ENST00000425490.1
TRIM22

tripartite motif containing 22

chr1_-_92952433 0.089 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr8_-_93978357 0.088 ENST00000522925.1
ENST00000522903.1
ENST00000537541.1
ENST00000518748.1
ENST00000519069.1
ENST00000521988.1
TRIQK





triple QxxK/R motif containing





chr1_+_15668240 0.086 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr4_-_103748880 0.083 ENST00000453744.2
ENST00000349311.8
UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr6_-_32095968 0.080 ENST00000375203.3
ENST00000375201.4
ATF6B

activating transcription factor 6 beta

chr11_+_2405833 0.079 ENST00000527343.1
ENST00000464784.2
CD81

CD81 molecule

chr6_-_7313381 0.079 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
SSR1






signal sequence receptor, alpha






chr7_+_43966018 0.078 ENST00000222402.3
ENST00000446008.1
ENST00000394798.4
UBE2D4


ubiquitin-conjugating enzyme E2D 4 (putative)


chr4_-_74486109 0.076 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr12_+_8666126 0.076 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr12_-_118796910 0.075 ENST00000541186.1
ENST00000539872.1
TAOK3

TAO kinase 3

chr19_-_51920952 0.073 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10





sialic acid binding Ig-like lectin 10





chr3_-_160823158 0.071 ENST00000392779.2
ENST00000392780.1
ENST00000494173.1
B3GALNT1


beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)


chr2_-_3521518 0.070 ENST00000382093.5
ADI1
acireductone dioxygenase 1
chr11_+_60383204 0.070 ENST00000412599.1
ENST00000320202.4
LINC00301

long intergenic non-protein coding RNA 301

chr3_-_160823040 0.068 ENST00000484127.1
ENST00000492353.1
ENST00000473142.1
ENST00000468268.1
ENST00000460353.1
ENST00000320474.4
ENST00000392781.2
B3GALNT1






beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)






chr4_-_74486347 0.068 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_-_46126093 0.066 ENST00000295452.4
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr1_-_151431647 0.066 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ




pogo transposable element with ZNF domain




chrX_+_108779004 0.066 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr3_+_148709128 0.066 ENST00000345003.4
ENST00000296048.6
ENST00000483267.1
GYG1


glycogenin 1


chr2_-_89340242 0.064 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr17_-_2996290 0.063 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr5_+_140227357 0.062 ENST00000378122.3
PCDHA9
protocadherin alpha 9
chr17_+_37784749 0.062 ENST00000394265.1
ENST00000394267.2
PPP1R1B

protein phosphatase 1, regulatory (inhibitor) subunit 1B

chr1_+_207226574 0.059 ENST00000367080.3
ENST00000367079.2
PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr6_+_154360357 0.052 ENST00000330432.7
ENST00000360422.4
OPRM1

opioid receptor, mu 1

chr10_-_75415825 0.051 ENST00000394810.2
SYNPO2L
synaptopodin 2-like
chr20_-_50418947 0.049 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr2_-_225811747 0.049 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr17_-_39341594 0.046 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr10_-_4285923 0.046 ENST00000418372.1
ENST00000608792.1
LINC00702

long intergenic non-protein coding RNA 702

chr20_-_50418972 0.045 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr19_-_3557570 0.045 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr6_+_161123270 0.045 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG


plasminogen


chr21_+_33671160 0.044 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr15_+_75970672 0.041 ENST00000435356.1
AC105020.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr2_-_231860596 0.041 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
AC105344.2






SPATA3 antisense RNA 1 (head to head)






chr1_-_24306835 0.041 ENST00000484146.2
SRSF10
serine/arginine-rich splicing factor 10
chr4_+_110736659 0.040 ENST00000394631.3
ENST00000226796.6
GAR1

GAR1 ribonucleoprotein

chr11_+_114168085 0.039 ENST00000541754.1
NNMT
nicotinamide N-methyltransferase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.4 1.5 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.3 1.0 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 3.9 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.2 4.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.2 1.6 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.2 1.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.8 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.4 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 2.0 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 0.2 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.2 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.6 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805) 'de novo' NAD biosynthetic process(GO:0034627)
0.1 0.7 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.8 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.5 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.4 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.3 GO:0007411 axon guidance(GO:0007411)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.3 GO:0010226 response to lithium ion(GO:0010226)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 2.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.7 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.6 GO:0043203 axon hillock(GO:0043203)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.7 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.6 2.2 GO:0061714 folic acid receptor activity(GO:0061714)
0.4 1.6 GO:0019770 IgG receptor activity(GO:0019770)
0.3 1.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.3 1.5 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 3.9 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 1.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.0 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 2.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.2 GO:0004797 thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.7 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.8 GO:0070330 aromatase activity(GO:0070330)
0.0 0.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.0 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.0 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.0 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.1 PID_IFNG_PATHWAY IFN-gamma pathway
0.0 4.0 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID_BMP_PATHWAY BMP receptor signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.1 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.6 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.1 0.7 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.8 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors