Motif ID: ALX1_ARX

Z-value: 0.406

Transcription factors associated with ALX1_ARX:

Gene SymbolEntrez IDGene Name
ALX1 ENSG00000180318.3 ALX1
ARX ENSG00000004848.6 ARX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ARXhg19_v2_chrX_-_25034065_25034088-0.331.2e-01Click!
ALX1hg19_v2_chr12_+_85673868_85673885-0.086.9e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of ALX1_ARX

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_102413726 0.889 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_+_50569575 0.797 ENST00000371827.1
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr6_+_34204642 0.770 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr4_+_69313145 0.581 ENST00000305363.4
TMPRSS11E
transmembrane protease, serine 11E
chr17_+_39261584 0.546 ENST00000391415.1
KRTAP4-9
keratin associated protein 4-9
chr14_-_95236551 0.538 ENST00000238558.3
GSC
goosecoid homeobox
chr1_+_84630645 0.475 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_-_93520259 0.462 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr3_-_141747950 0.459 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr1_-_94147385 0.455 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr4_+_169013666 0.443 ENST00000359299.3
ANXA10
annexin A10
chr10_-_75226166 0.414 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr7_-_93520191 0.393 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr1_-_151148492 0.375 ENST00000295314.4
TMOD4
tropomodulin 4 (muscle)
chr1_-_151148442 0.362 ENST00000441701.1
ENST00000416280.2
TMOD4

tropomodulin 4 (muscle)

chr10_+_69865866 0.361 ENST00000354393.2
MYPN
myopalladin
chr8_-_10512569 0.359 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr2_-_145278475 0.352 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr12_-_89746173 0.335 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr8_-_122653630 0.322 ENST00000303924.4
HAS2
hyaluronan synthase 2
chrX_+_107288239 0.301 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr3_+_111393501 0.295 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chrX_+_107288197 0.291 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr1_+_92632542 0.271 ENST00000409154.4
ENST00000370378.4
KIAA1107

KIAA1107

chr8_-_91095099 0.268 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr15_+_42066632 0.256 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1



mitogen-activated protein kinase binding protein 1



chr19_+_7030589 0.256 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr17_-_60885700 0.255 ENST00000583600.1
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr17_-_60885659 0.253 ENST00000311269.5
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr5_-_39270725 0.251 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB


FYN binding protein


chr5_+_36152179 0.247 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
SKP2


S-phase kinase-associated protein 2, E3 ubiquitin protein ligase


chr9_+_124329336 0.242 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP


DAB2 interacting protein


chr2_+_65215604 0.241 ENST00000531327.1
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr1_+_154401791 0.235 ENST00000476006.1
IL6R
interleukin 6 receptor
chr17_+_74463650 0.227 ENST00000392492.3
AANAT
aralkylamine N-acetyltransferase
chr18_-_44181442 0.226 ENST00000398722.4
LOXHD1
lipoxygenase homology domains 1
chrY_-_6742068 0.226 ENST00000215479.5
AMELY
amelogenin, Y-linked
chr1_+_206557366 0.224 ENST00000414007.1
ENST00000419187.2
SRGAP2

SLIT-ROBO Rho GTPase activating protein 2

chr19_-_7040190 0.223 ENST00000381394.4
MBD3L4
methyl-CpG binding domain protein 3-like 4
chr18_-_19994830 0.219 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chr19_+_7049332 0.215 ENST00000381393.3
MBD3L2
methyl-CpG binding domain protein 3-like 2
chr2_-_31440377 0.214 ENST00000444918.2
ENST00000403897.3
CAPN14

calpain 14

chr1_+_62439037 0.210 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr10_+_18689637 0.209 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr12_+_1099675 0.207 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr6_-_66417107 0.197 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS



eyes shut homolog (Drosophila)



chr18_+_616672 0.187 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr3_-_141747439 0.185 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr14_-_81425828 0.183 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128


centrosomal protein 128kDa


chr19_-_6393465 0.181 ENST00000394456.5
GTF2F1
general transcription factor IIF, polypeptide 1, 74kDa
chr10_-_29923893 0.180 ENST00000355867.4
SVIL
supervillin
chr14_+_57671888 0.179 ENST00000391612.1
AL391152.1
AL391152.1
chr5_+_36152091 0.172 ENST00000274254.5
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr14_+_24099318 0.165 ENST00000432832.2
DHRS2
dehydrogenase/reductase (SDR family) member 2
chr5_+_36152163 0.163 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr19_-_6393216 0.162 ENST00000595047.1
GTF2F1
general transcription factor IIF, polypeptide 1, 74kDa
chr2_+_228678550 0.161 ENST00000409189.3
ENST00000358813.4
CCL20

chemokine (C-C motif) ligand 20

chr17_+_3118915 0.158 ENST00000304094.1
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr7_+_138915102 0.154 ENST00000486663.1
UBN2
ubinuclein 2
chr18_+_616711 0.154 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr17_-_3030875 0.153 ENST00000328890.2
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chr2_+_58655461 0.149 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1


long intergenic non-protein coding RNA 1122


chr7_+_93535817 0.147 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr12_-_67197760 0.145 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1



glutamate receptor interacting protein 1



chr1_-_21377383 0.144 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chrX_+_11311533 0.142 ENST00000380714.3
ENST00000380712.3
ENST00000348912.4
AMELX


amelogenin, X-linked


chr7_-_14880892 0.141 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB


diacylglycerol kinase, beta 90kDa


chr12_+_122688090 0.139 ENST00000324189.4
ENST00000546192.1
B3GNT4

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

chr1_+_52682052 0.138 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr11_+_55029628 0.130 ENST00000417545.2
TRIM48
tripartite motif containing 48
chr6_-_26199499 0.129 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr4_+_156824840 0.129 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr8_+_77318769 0.125 ENST00000518732.1
RP11-706J10.1
long intergenic non-protein coding RNA 1111
chr18_+_10471826 0.124 ENST00000584596.2
APCDD1
adenomatosis polyposis coli down-regulated 1
chr6_+_26199737 0.124 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr1_+_192127578 0.124 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr15_+_80733570 0.124 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
ARNT2


aryl-hydrocarbon receptor nuclear translocator 2


chr3_+_130569429 0.123 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr4_-_143227088 0.121 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr9_+_77230499 0.120 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr15_-_34331243 0.120 ENST00000306730.3
AVEN
apoptosis, caspase activation inhibitor
chr2_+_161993465 0.117 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr4_-_122854612 0.116 ENST00000264811.5
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr3_-_87325728 0.113 ENST00000350375.2
POU1F1
POU class 1 homeobox 1
chr1_-_234667504 0.112 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1

RP5-855F14.1

chr3_+_121774202 0.111 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86



CD86 molecule



chrX_+_119737806 0.111 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr2_+_54683419 0.110 ENST00000356805.4
SPTBN1
spectrin, beta, non-erythrocytic 1
chr2_+_185463093 0.107 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr4_-_89951028 0.105 ENST00000506913.1
FAM13A
family with sequence similarity 13, member A
chr3_-_33759699 0.104 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
CLASP2


cytoplasmic linker associated protein 2


chr17_-_39023462 0.104 ENST00000251643.4
KRT12
keratin 12
chr2_+_75873902 0.104 ENST00000393909.2
ENST00000358788.6
ENST00000409374.1
MRPL19


mitochondrial ribosomal protein L19


chr1_-_200379180 0.103 ENST00000294740.3
ZNF281
zinc finger protein 281
chr3_-_87325612 0.103 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU1F1


POU class 1 homeobox 1


chr6_-_107235331 0.101 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1

RP1-60O19.1

chr5_+_38148582 0.100 ENST00000508853.1
CTD-2207A17.1
CTD-2207A17.1
chr6_+_3259122 0.100 ENST00000438998.2
ENST00000380305.4
PSMG4

proteasome (prosome, macropain) assembly chaperone 4

chr3_-_27763803 0.099 ENST00000449599.1
EOMES
eomesodermin
chr4_-_119759795 0.096 ENST00000419654.2
SEC24D
SEC24 family member D
chr2_+_234600253 0.096 ENST00000373424.1
ENST00000441351.1
UGT1A6

UDP glucuronosyltransferase 1 family, polypeptide A6

chr3_-_194188956 0.095 ENST00000256031.4
ENST00000446356.1
ATP13A3

ATPase type 13A3

chr12_-_57873631 0.095 ENST00000393791.3
ENST00000356411.2
ENST00000552249.1
ARHGAP9


Rho GTPase activating protein 9


chr17_+_39240459 0.093 ENST00000391417.4
KRTAP4-7
keratin associated protein 4-7
chr5_+_68860949 0.092 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr12_+_104337515 0.090 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr5_+_59783941 0.086 ENST00000506884.1
ENST00000504876.2
PART1

prostate androgen-regulated transcript 1 (non-protein coding)

chr10_-_50396407 0.086 ENST00000374153.2
ENST00000374151.3
C10orf128

chromosome 10 open reading frame 128

chr7_+_107224364 0.086 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chrX_+_38211777 0.085 ENST00000039007.4
OTC
ornithine carbamoyltransferase
chr10_-_112064665 0.082 ENST00000369603.5
SMNDC1
survival motor neuron domain containing 1
chr6_+_45296391 0.081 ENST00000371436.6
ENST00000576263.1
RUNX2

runt-related transcription factor 2

chr8_-_86253888 0.079 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1


carbonic anhydrase I


chr6_+_26087646 0.078 ENST00000309234.6
HFE
hemochromatosis
chr6_-_107235287 0.076 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1


RP1-60O19.1


chr4_-_103940791 0.076 ENST00000510559.1
ENST00000394789.3
ENST00000296422.7
SLC9B1


solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1


chr2_-_166930131 0.076 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr11_+_120973375 0.076 ENST00000264037.2
TECTA
tectorin alpha
chr11_+_128563652 0.076 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr4_+_95128748 0.075 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_-_150067696 0.073 ENST00000340413.2
ENST00000367403.3
NUP43

nucleoporin 43kDa

chr6_-_99797522 0.073 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chr3_-_47934234 0.073 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr5_+_59783540 0.071 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr4_+_118955500 0.070 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr12_-_57873329 0.069 ENST00000424809.2
ARHGAP9
Rho GTPase activating protein 9
chr1_-_110933611 0.068 ENST00000472422.2
ENST00000437429.2
SLC16A4

solute carrier family 16, member 4

chr12_+_59989918 0.068 ENST00000547379.1
ENST00000549465.1
SLC16A7

solute carrier family 16 (monocarboxylate transporter), member 7

chr3_-_190167571 0.068 ENST00000354905.2
TMEM207
transmembrane protein 207
chr1_-_12946025 0.065 ENST00000235349.5
PRAMEF4
PRAME family member 4
chr1_+_44679113 0.065 ENST00000361745.6
ENST00000446292.1
ENST00000440641.1
ENST00000436069.1
ENST00000437511.1
DMAP1




DNA methyltransferase 1 associated protein 1




chr1_+_104615595 0.065 ENST00000418362.1
RP11-364B6.1
RP11-364B6.1
chr1_+_186798073 0.065 ENST00000367466.3
ENST00000442353.2
PLA2G4A

phospholipase A2, group IVA (cytosolic, calcium-dependent)

chr2_+_161993412 0.064 ENST00000259075.2
ENST00000432002.1
TANK

TRAF family member-associated NFKB activator

chr8_+_39792474 0.064 ENST00000502986.2
IDO2
indoleamine 2,3-dioxygenase 2
chr1_+_44679159 0.064 ENST00000315913.5
ENST00000372289.2
DMAP1

DNA methyltransferase 1 associated protein 1

chr10_+_53806501 0.064 ENST00000373975.2
PRKG1
protein kinase, cGMP-dependent, type I
chr14_+_95078714 0.063 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3


serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3


chr8_-_62602327 0.061 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH









aspartate beta-hydroxylase









chr11_-_7847519 0.061 ENST00000328375.1
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr2_+_152214098 0.060 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr3_-_101039402 0.060 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr18_+_66465302 0.060 ENST00000360242.5
ENST00000358653.5
CCDC102B

coiled-coil domain containing 102B

chr6_+_12007963 0.059 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr9_+_42671887 0.059 ENST00000456520.1
ENST00000377391.3
CBWD7

COBW domain containing 7

chrX_-_11284095 0.058 ENST00000303025.6
ENST00000534860.1
ARHGAP6

Rho GTPase activating protein 6

chr3_+_12329397 0.058 ENST00000397015.2
PPARG
peroxisome proliferator-activated receptor gamma
chr17_-_39254391 0.057 ENST00000333822.4
KRTAP4-8
keratin associated protein 4-8
chr1_+_186265399 0.054 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4






proteoglycan 4






chr11_-_92931098 0.054 ENST00000326402.4
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr17_-_71228357 0.053 ENST00000583024.1
ENST00000403627.3
ENST00000405159.3
ENST00000581110.1
FAM104A



family with sequence similarity 104, member A



chr3_+_12329358 0.053 ENST00000309576.6
PPARG
peroxisome proliferator-activated receptor gamma
chr19_-_38183201 0.052 ENST00000590008.1
ENST00000358582.4
ZNF781

zinc finger protein 781

chr10_+_89420706 0.052 ENST00000427144.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr16_+_1728257 0.052 ENST00000248098.3
ENST00000562684.1
ENST00000561516.1
ENST00000382711.5
ENST00000566742.1
HN1L




hematological and neurological expressed 1-like




chr12_+_10163231 0.052 ENST00000396502.1
ENST00000338896.5
CLEC12B

C-type lectin domain family 12, member B

chr8_+_38677850 0.052 ENST00000518809.1
ENST00000520611.1
TACC1

transforming, acidic coiled-coil containing protein 1

chr5_+_145826867 0.051 ENST00000296702.5
ENST00000394421.2
TCERG1

transcription elongation regulator 1

chr4_-_143226979 0.050 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr2_+_179184955 0.050 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr18_-_13915530 0.049 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr12_+_18414446 0.049 ENST00000433979.1
PIK3C2G
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr4_+_109571740 0.048 ENST00000361564.4
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr11_+_85359062 0.047 ENST00000532180.1
TMEM126A
transmembrane protein 126A
chr1_+_158978768 0.046 ENST00000447473.2
IFI16
interferon, gamma-inducible protein 16
chr11_+_85359002 0.046 ENST00000528105.1
ENST00000304511.2
TMEM126A

transmembrane protein 126A

chr4_+_88571429 0.046 ENST00000339673.6
ENST00000282479.7
DMP1

dentin matrix acidic phosphoprotein 1

chr11_+_55578854 0.046 ENST00000333973.2
OR5L1
olfactory receptor, family 5, subfamily L, member 1
chr3_-_98241760 0.045 ENST00000507874.1
ENST00000502299.1
ENST00000508659.1
ENST00000510545.1
ENST00000511667.1
ENST00000394185.2
ENST00000394181.2
ENST00000508902.1
ENST00000341181.6
ENST00000437922.1
ENST00000394180.2
CLDND1










claudin domain containing 1










chr4_+_95128996 0.045 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_-_26199471 0.045 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr11_-_13517565 0.045 ENST00000282091.1
ENST00000529816.1
PTH

parathyroid hormone

chr12_-_52946923 0.045 ENST00000267119.5
KRT71
keratin 71
chr7_-_7575477 0.044 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr12_-_112123524 0.042 ENST00000327551.6
BRAP
BRCA1 associated protein
chr4_+_109571800 0.042 ENST00000512478.2
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr3_-_27764190 0.041 ENST00000537516.1
EOMES
eomesodermin
chr8_-_6420930 0.040 ENST00000325203.5
ANGPT2
angiopoietin 2
chr5_+_137203465 0.039 ENST00000239926.4
MYOT
myotilin
chr9_-_27005686 0.039 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chr4_-_174320687 0.038 ENST00000296506.3
SCRG1
stimulator of chondrogenesis 1
chr3_-_167191814 0.038 ENST00000466903.1
ENST00000264677.4
SERPINI2

serpin peptidase inhibitor, clade I (pancpin), member 2

chr9_+_44867571 0.038 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chr11_+_113779704 0.038 ENST00000537778.1
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr12_-_118797475 0.036 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3


TAO kinase 3


chr15_+_44092784 0.036 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr10_+_97803151 0.035 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
CCNJ



cyclin J



chr3_+_159943362 0.034 ENST00000326474.3
C3orf80
chromosome 3 open reading frame 80
chr6_-_133055896 0.034 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3





vanin 3





chr14_-_81893734 0.034 ENST00000555447.1
STON2
stonin 2
chr9_+_135854091 0.033 ENST00000450530.1
ENST00000534944.1
GFI1B

growth factor independent 1B transcription repressor

chr3_-_124774802 0.033 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr2_-_145275228 0.032 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2



zinc finger E-box binding homeobox 2



chr19_-_54619006 0.032 ENST00000391759.1
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr5_-_134735568 0.031 ENST00000510038.1
ENST00000304332.4
H2AFY

H2A histone family, member Y

chr1_-_200379129 0.031 ENST00000367353.1
ZNF281
zinc finger protein 281
chr3_-_196242233 0.030 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr2_-_145277882 0.029 ENST00000465070.1
ENST00000444559.1
ZEB2

zinc finger E-box binding homeobox 2

chr1_-_110155671 0.029 ENST00000351050.3
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr7_+_55980331 0.029 ENST00000429591.2
ZNF713
zinc finger protein 713

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.2 0.8 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.6 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.5 GO:0097338 response to clozapine(GO:0097338)
0.1 0.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.2 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:2001186 negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186)
0.0 0.1 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.7 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.3 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.0 0.7 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.9 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.0 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.0 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.0 GO:1904815 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.5 GO:0042461 photoreceptor cell development(GO:0042461)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.1 0.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.2 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544) DBD domain binding(GO:0050692)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.5 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.9 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.6 PID_MYC_PATHWAY C-MYC pathway
0.0 0.5 PID_IL12_STAT4_PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling