Motif ID: AGUGGUU

Z-value: 0.710


Mature miRNA associated with seed AGUGGUU:

NamemiRBase Accession
hsa-miR-140-5p MIMAT0000431



Activity profile for motif AGUGGUU.

activity profile for motif AGUGGUU


Sorted Z-values histogram for motif AGUGGUU

Sorted Z-values for motif AGUGGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGUGGUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_81071684 1.486 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199


KIAA1199


chr14_+_85996471 1.476 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_-_20812690 1.439 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr9_+_131174024 1.413 ENST00000420034.1
ENST00000372842.1
CERCAM

cerebral endothelial cell adhesion molecule

chr20_+_6748311 1.290 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr5_-_127873659 1.259 ENST00000262464.4
FBN2
fibrillin 2
chr1_+_178694300 0.944 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr7_-_98741642 0.927 ENST00000361368.2
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr8_+_26435359 0.912 ENST00000311151.5
DPYSL2
dihydropyrimidinase-like 2
chr19_-_2096259 0.908 ENST00000588048.1
ENST00000357066.3
MOB3A

MOB kinase activator 3A

chr17_-_33448468 0.901 ENST00000587405.1
ENST00000591723.1
ENST00000593039.1
RAD51D
RAD51L3-RFFL

RAD51 paralog D
Uncharacterized protein

chr1_+_182992545 0.893 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr7_+_2671568 0.891 ENST00000258796.7
TTYH3
tweety family member 3
chr1_-_109825719 0.879 ENST00000369904.3
ENST00000369903.2
ENST00000429031.1
ENST00000418914.2
ENST00000409267.1
PSRC1




proline/serine-rich coiled-coil 1




chr2_+_48541776 0.846 ENST00000413569.1
ENST00000340553.3
FOXN2

forkhead box N2

chr5_-_77844974 0.834 ENST00000515007.2
LHFPL2
lipoma HMGIC fusion partner-like 2
chr14_+_65171099 0.833 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_+_11994715 0.818 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
PLOD1



procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1



chr9_+_112810878 0.750 ENST00000434623.2
ENST00000374525.1
AKAP2

A kinase (PRKA) anchor protein 2

chr6_+_43737939 0.750 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr3_+_150126101 0.740 ENST00000361875.3
ENST00000361136.2
TSC22D2

TSC22 domain family, member 2

chr9_+_112542572 0.721 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr6_-_88411911 0.719 ENST00000257787.5
AKIRIN2
akirin 2
chr15_-_42264702 0.673 ENST00000220325.4
EHD4
EH-domain containing 4
chr9_+_132815985 0.664 ENST00000372410.3
GPR107
G protein-coupled receptor 107
chr5_+_149887672 0.663 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr12_+_113659234 0.654 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
TPCN1





two pore segment channel 1





chr11_-_46940074 0.611 ENST00000378623.1
ENST00000534404.1
LRP4

low density lipoprotein receptor-related protein 4

chr20_-_10654639 0.610 ENST00000254958.5
JAG1
jagged 1
chr15_+_38544476 0.610 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr5_-_172756506 0.599 ENST00000265087.4
STC2
stanniocalcin 2
chr10_-_3827417 0.581 ENST00000497571.1
ENST00000542957.1
KLF6

Kruppel-like factor 6

chr19_+_11200038 0.580 ENST00000558518.1
ENST00000557933.1
ENST00000455727.2
ENST00000535915.1
ENST00000545707.1
ENST00000558013.1
LDLR





low density lipoprotein receptor





chr22_-_36784035 0.559 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chr17_-_33416231 0.554 ENST00000584655.1
ENST00000447669.2
ENST00000315249.7
RFFL


ring finger and FYVE-like domain containing E3 ubiquitin protein ligase


chr1_-_117210290 0.539 ENST00000369483.1
ENST00000369486.3
IGSF3

immunoglobulin superfamily, member 3

chr2_-_172290482 0.538 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
METTL8


methyltransferase like 8


chr9_-_99801592 0.531 ENST00000259470.5
CTSV
cathepsin V
chr12_-_27167233 0.522 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
TM7SF3






transmembrane 7 superfamily member 3






chr7_+_39663061 0.498 ENST00000005257.2
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr2_+_14775215 0.494 ENST00000581929.1
AC011897.1
Uncharacterized protein
chr21_-_15755446 0.488 ENST00000544452.1
ENST00000285667.3
HSPA13

heat shock protein 70kDa family, member 13

chr5_+_72251793 0.486 ENST00000430046.2
ENST00000341845.6
FCHO2

FCH domain only 2

chr3_-_124774802 0.486 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr10_+_11206925 0.446 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CELF2


CUGBP, Elav-like family member 2


chr5_+_14581884 0.443 ENST00000274217.3
FAM105A
family with sequence similarity 105, member A
chr22_-_22221900 0.427 ENST00000215832.6
ENST00000398822.3
MAPK1

mitogen-activated protein kinase 1

chr20_-_48729670 0.407 ENST00000371657.5
UBE2V1
ubiquitin-conjugating enzyme E2 variant 1
chr4_-_152147579 0.407 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3D19



SH3 domain containing 19



chr2_+_208576355 0.404 ENST00000420822.1
ENST00000295414.3
ENST00000339882.5
CCNYL1


cyclin Y-like 1


chr9_-_73029540 0.402 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr6_+_41040678 0.379 ENST00000341376.6
ENST00000353205.5
NFYA

nuclear transcription factor Y, alpha

chr3_+_152879985 0.377 ENST00000323534.2
RAP2B
RAP2B, member of RAS oncogene family
chr5_+_14143728 0.375 ENST00000344204.4
ENST00000537187.1
TRIO

trio Rho guanine nucleotide exchange factor

chr19_-_51523275 0.375 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr22_-_50913371 0.372 ENST00000348911.6
ENST00000380817.3
ENST00000390679.3
SBF1


SET binding factor 1


chr19_-_41196534 0.372 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr17_+_36508111 0.359 ENST00000331159.5
ENST00000577233.1
SOCS7

suppressor of cytokine signaling 7

chr8_-_66754172 0.357 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr8_-_141645645 0.355 ENST00000519980.1
ENST00000220592.5
AGO2

argonaute RISC catalytic component 2

chr19_+_39616410 0.354 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4






p21 protein (Cdc42/Rac)-activated kinase 4






chr15_-_83876758 0.350 ENST00000299633.4
HDGFRP3
Hepatoma-derived growth factor-related protein 3
chr3_-_149688896 0.343 ENST00000239940.7
PFN2
profilin 2
chr5_+_126112794 0.342 ENST00000261366.5
ENST00000395354.1
LMNB1

lamin B1

chr4_+_128703295 0.342 ENST00000296464.4
ENST00000508549.1
HSPA4L

heat shock 70kDa protein 4-like

chr20_-_48770244 0.341 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
TMEM189


transmembrane protein 189


chr7_-_32931387 0.337 ENST00000304056.4
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr22_-_18507279 0.334 ENST00000441493.2
ENST00000444520.1
ENST00000207726.7
ENST00000429452.1
MICAL3



microtubule associated monooxygenase, calponin and LIM domain containing 3



chr5_-_141704566 0.330 ENST00000344120.4
ENST00000434127.2
SPRY4

sprouty homolog 4 (Drosophila)

chr17_-_53499310 0.330 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr20_-_48770174 0.330 ENST00000341698.2
TMEM189-UBE2V1
TMEM189-UBE2V1 readthrough
chr4_+_155665123 0.326 ENST00000336356.3
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr10_-_99052382 0.322 ENST00000466484.1
ENST00000358531.4
ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ARHGAP19

ARHGAP19-SLIT1


Rho GTPase activating protein 19

ARHGAP19-SLIT1 readthrough (NMD candidate)


chr9_+_5629025 0.321 ENST00000251879.6
ENST00000414202.2
KIAA1432

KIAA1432

chr4_+_55095264 0.319 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr5_-_16936340 0.313 ENST00000507288.1
ENST00000513610.1
MYO10

myosin X

chr12_+_107168342 0.311 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr13_+_22245522 0.310 ENST00000382353.5
FGF9
fibroblast growth factor 9
chr14_-_100070363 0.307 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chrX_-_72299258 0.306 ENST00000453389.1
ENST00000373519.1
PABPC1L2A

poly(A) binding protein, cytoplasmic 1-like 2A

chr1_-_68299130 0.305 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr15_-_30114622 0.300 ENST00000495972.2
ENST00000346128.6
TJP1

tight junction protein 1

chr9_-_95432536 0.297 ENST00000287996.3
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr22_+_19118321 0.295 ENST00000399635.2
TSSK2
testis-specific serine kinase 2
chrX_-_70288234 0.274 ENST00000276105.3
ENST00000374274.3
SNX12

sorting nexin 12

chr10_+_96162242 0.274 ENST00000225235.4
TBC1D12
TBC1 domain family, member 12
chr3_+_51575596 0.268 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr14_+_37131058 0.260 ENST00000361487.6
PAX9
paired box 9
chr20_-_46415297 0.260 ENST00000467815.1
ENST00000359930.4
SULF2

sulfatase 2

chr2_+_26256938 0.260 ENST00000264710.4
RAB10
RAB10, member RAS oncogene family
chr20_+_19997948 0.259 ENST00000310450.4
ENST00000398602.2
NAA20

N(alpha)-acetyltransferase 20, NatB catalytic subunit

chr9_-_115095883 0.256 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
PTBP3



polypyrimidine tract binding protein 3



chr21_+_30671189 0.256 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr6_+_53883708 0.254 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP


muscular LMNA-interacting protein


chr8_+_70378852 0.247 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1


sulfatase 1


chr1_+_101702417 0.243 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr17_+_18218587 0.240 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr6_-_108395907 0.238 ENST00000193322.3
OSTM1
osteopetrosis associated transmembrane protein 1
chrX_+_37208521 0.236 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr9_+_101867359 0.236 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr9_-_107690420 0.232 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr15_+_90544532 0.224 ENST00000268154.4
ZNF710
zinc finger protein 710
chr12_+_45609893 0.223 ENST00000320560.8
ANO6
anoctamin 6
chr6_-_110500905 0.222 ENST00000392587.2
WASF1
WAS protein family, member 1
chr1_+_82266053 0.222 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2






latrophilin 2






chr7_-_42276612 0.221 ENST00000395925.3
ENST00000437480.1
GLI3

GLI family zinc finger 3

chr18_-_24445729 0.221 ENST00000383168.4
AQP4
aquaporin 4
chr9_-_23821273 0.218 ENST00000380110.4
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chrX_+_72223352 0.213 ENST00000373521.2
ENST00000538388.1
PABPC1L2B

poly(A) binding protein, cytoplasmic 1-like 2B

chr2_+_202316392 0.208 ENST00000194530.3
ENST00000392249.2
STRADB

STE20-related kinase adaptor beta

chr9_-_37034028 0.197 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5










paired box 5










chr4_+_124320665 0.192 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chrX_+_107069063 0.186 ENST00000262843.6
MID2
midline 2
chr3_+_15468862 0.183 ENST00000396842.2
EAF1
ELL associated factor 1
chr1_-_43424500 0.182 ENST00000415851.2
ENST00000426263.3
ENST00000372500.3
SLC2A1


solute carrier family 2 (facilitated glucose transporter), member 1


chr6_+_4890226 0.177 ENST00000343762.5
CDYL
chromodomain protein, Y-like
chr8_+_142402089 0.176 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3


protein tyrosine phosphatase type IVA, member 3


chr14_+_57046500 0.175 ENST00000261556.6
TMEM260
transmembrane protein 260
chr8_-_8751068 0.174 ENST00000276282.6
MFHAS1
malignant fibrous histiocytoma amplified sequence 1
chr16_-_20911641 0.172 ENST00000324344.4
ENST00000564349.1
DCUN1D3
ERI2
DCN1, defective in cullin neddylation 1, domain containing 3
ERI1 exoribonuclease family member 2
chr14_-_75330537 0.172 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
PROX2


prospero homeobox 2


chr11_-_31839488 0.167 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6


paired box 6


chr11_+_74459876 0.167 ENST00000299563.4
RNF169
ring finger protein 169
chr2_-_183903133 0.167 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr11_+_64948665 0.166 ENST00000533820.1
CAPN1
calpain 1, (mu/I) large subunit
chr3_+_57741957 0.165 ENST00000295951.3
SLMAP
sarcolemma associated protein
chr11_+_12695944 0.159 ENST00000361905.4
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr17_-_16395455 0.159 ENST00000409083.3
FAM211A
family with sequence similarity 211, member A
chr15_-_23086394 0.158 ENST00000337435.4
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr18_-_57027194 0.155 ENST00000251047.5
LMAN1
lectin, mannose-binding, 1
chr5_+_32788945 0.153 ENST00000326958.1
AC026703.1
AC026703.1
chr15_-_56535464 0.152 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
RFX7



regulatory factor X, 7



chr7_+_91875508 0.151 ENST00000265742.3
ANKIB1
ankyrin repeat and IBR domain containing 1
chr1_+_78470530 0.149 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr3_-_196159268 0.145 ENST00000381887.3
ENST00000535858.1
ENST00000428095.1
ENST00000296328.4
UBXN7



UBX domain protein 7



chr1_+_10271674 0.142 ENST00000377086.1
KIF1B
kinesin family member 1B
chr5_-_168006591 0.141 ENST00000239231.6
PANK3
pantothenate kinase 3
chr14_-_74485960 0.131 ENST00000556242.1
ENST00000334696.6
ENTPD5

ectonucleoside triphosphate diphosphohydrolase 5

chr1_+_197881592 0.129 ENST00000367391.1
ENST00000367390.3
LHX9

LIM homeobox 9

chr3_+_196594727 0.128 ENST00000445299.2
ENST00000323460.5
ENST00000419026.1
SENP5


SUMO1/sentrin specific peptidase 5


chr14_+_69726656 0.127 ENST00000337827.4
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr14_+_23775971 0.125 ENST00000250405.5
BCL2L2
BCL2-like 2
chr13_-_25746416 0.125 ENST00000515384.1
ENST00000357816.2
AMER2

APC membrane recruitment protein 2

chrX_+_28605516 0.121 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr1_+_100503643 0.120 ENST00000370152.3
HIAT1
hippocampus abundant transcript 1
chr8_+_38854418 0.118 ENST00000481513.1
ENST00000487273.2
ADAM9

ADAM metallopeptidase domain 9

chr3_-_42623428 0.116 ENST00000423701.2
ENST00000420163.1
ENST00000416880.1
ENST00000536332.1
ENST00000264454.3
ENST00000273156.7
SEC22C





SEC22 vesicle trafficking protein homolog C (S. cerevisiae)





chr9_+_98534605 0.116 ENST00000600140.1
DKFZP434H0512
Protein LOC100506667; Putative uncharacterized protein DKFZp434H0512
chr1_+_175036966 0.115 ENST00000239462.4
TNN
tenascin N
chr9_+_132934835 0.115 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr18_-_34409116 0.114 ENST00000334295.4
TPGS2
tubulin polyglutamylase complex subunit 2
chr17_+_4710391 0.113 ENST00000263088.6
ENST00000572940.1
PLD2

phospholipase D2

chr16_+_69221028 0.111 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr6_-_90062543 0.108 ENST00000435041.2
UBE2J1
ubiquitin-conjugating enzyme E2, J1
chr4_+_71768043 0.107 ENST00000502869.1
ENST00000309395.2
ENST00000396051.2
MOB1B


MOB kinase activator 1B


chr10_+_70091812 0.107 ENST00000265866.7
HNRNPH3
heterogeneous nuclear ribonucleoprotein H3 (2H9)
chr8_-_67579418 0.106 ENST00000310421.4
VCPIP1
valosin containing protein (p97)/p47 complex interacting protein 1
chr3_-_50396978 0.103 ENST00000266025.3
TMEM115
transmembrane protein 115
chr2_-_37193606 0.098 ENST00000379213.2
ENST00000263918.4
STRN

striatin, calmodulin binding protein

chr5_-_180242534 0.097 ENST00000333055.3
ENST00000513431.1
MGAT1

mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase

chr19_+_48972459 0.091 ENST00000427476.1
CYTH2
cytohesin 2
chr10_-_11653753 0.090 ENST00000609104.1
USP6NL
USP6 N-terminal like
chr17_-_4167142 0.089 ENST00000570535.1
ENST00000574367.1
ENST00000341657.4
ENST00000433651.1
ANKFY1



ankyrin repeat and FYVE domain containing 1



chr20_+_32250079 0.088 ENST00000375222.3
C20orf144
chromosome 20 open reading frame 144
chr12_-_111021110 0.086 ENST00000354300.3
PPTC7
PTC7 protein phosphatase homolog (S. cerevisiae)
chr12_-_96794143 0.085 ENST00000543119.2
CDK17
cyclin-dependent kinase 17
chr4_-_90229142 0.077 ENST00000609438.1
GPRIN3
GPRIN family member 3
chr14_-_55878538 0.076 ENST00000247178.5
ATG14
autophagy related 14
chr1_+_87380299 0.075 ENST00000370551.4
ENST00000370550.5
HS2ST1

heparan sulfate 2-O-sulfotransferase 1

chr2_-_37384175 0.072 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
EIF2AK2



eukaryotic translation initiation factor 2-alpha kinase 2



chr8_-_124286735 0.072 ENST00000395571.3
ZHX1
zinc fingers and homeoboxes 1
chr1_+_26348259 0.068 ENST00000374280.3
EXTL1
exostosin-like glycosyltransferase 1
chr6_-_82462425 0.068 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A


family with sequence similarity 46, member A


chr16_-_2264779 0.068 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr3_+_20081515 0.064 ENST00000263754.4
KAT2B
K(lysine) acetyltransferase 2B
chr3_+_134204881 0.064 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
CEP63


centrosomal protein 63kDa


chr5_+_32711419 0.061 ENST00000265074.8
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr10_-_104262426 0.059 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chrX_-_63425561 0.058 ENST00000374869.3
ENST00000330258.3
AMER1

APC membrane recruitment protein 1

chr4_+_17616253 0.058 ENST00000237380.7
MED28
mediator complex subunit 28
chr17_+_46908350 0.056 ENST00000258947.3
ENST00000509507.1
ENST00000448105.2
ENST00000570513.1
ENST00000509415.1
ENST00000513119.1
ENST00000416445.2
ENST00000508679.1
ENST00000505071.1
CALCOCO2








calcium binding and coiled-coil domain 2








chr11_+_117014983 0.053 ENST00000527958.1
ENST00000419197.2
ENST00000304808.6
ENST00000529887.2
PAFAH1B2



platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)



chr10_+_126490354 0.051 ENST00000298492.5
FAM175B
family with sequence similarity 175, member B
chr20_-_35374456 0.050 ENST00000373803.2
ENST00000359675.2
ENST00000540765.1
ENST00000349004.1
NDRG3



NDRG family member 3



chr11_-_66115032 0.043 ENST00000311181.4
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr5_-_131347306 0.043 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
ACSL6



acyl-CoA synthetase long-chain family member 6



chr9_-_100935043 0.039 ENST00000343933.5
CORO2A
coronin, actin binding protein, 2A
chr19_+_9945962 0.036 ENST00000587625.1
ENST00000247970.4
ENST00000588695.1
PIN1


peptidylprolyl cis/trans isomerase, NIMA-interacting 1


chr15_-_48937982 0.036 ENST00000316623.5
FBN1
fibrillin 1
chr7_-_75988321 0.030 ENST00000307630.3
YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chr16_-_66785699 0.029 ENST00000258198.2
DYNC1LI2
dynein, cytoplasmic 1, light intermediate chain 2
chr12_-_111180644 0.027 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
PPP1CC



protein phosphatase 1, catalytic subunit, gamma isozyme



chr1_+_171810606 0.027 ENST00000358155.4
ENST00000367733.2
ENST00000355305.5
ENST00000367731.1
DNM3



dynamin 3



chr14_-_82000140 0.025 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
SEL1L


sel-1 suppressor of lin-12-like (C. elegans)


chr16_-_57513657 0.023 ENST00000566936.1
ENST00000568617.1
ENST00000567276.1
ENST00000569548.1
ENST00000569250.1
ENST00000564378.1
DOK4





docking protein 4





chr7_+_128379346 0.022 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU





calumenin





chr3_+_180630090 0.020 ENST00000357559.4
ENST00000305586.7
FXR1

fragile X mental retardation, autosomal homolog 1

chr7_-_44924939 0.017 ENST00000395699.2
PURB
purine-rich element binding protein B
chr4_+_39046615 0.017 ENST00000261425.3
ENST00000508137.2
KLHL5

kelch-like family member 5

chr5_-_89825328 0.009 ENST00000500869.2
ENST00000315948.6
ENST00000509384.1
LYSMD3


LysM, putative peptidoglycan-binding, domain containing 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.3 0.9 GO:1902534 single-organism membrane invagination(GO:1902534)
0.3 0.8 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.2 0.7 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 1.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.2 0.6 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2 0.6 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 0.7 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.2 0.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.6 GO:1905167 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.4 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 1.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.4 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.6 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.1 0.5 GO:1990834 response to odorant(GO:1990834)
0.1 0.6 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.9 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.3 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.6 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.2 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.1 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.7 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.2 GO:0060935 cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.2 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.2 GO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.4 GO:0051414 response to cortisol(GO:0051414)
0.1 0.2 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.3 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.4 GO:0090625 siRNA loading onto RISC involved in RNA interference(GO:0035087) mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.5 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.5 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.9 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.4 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.3 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.9 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.8 GO:0006907 pinocytosis(GO:0006907)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670) negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.2 0.6 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.9 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.6 GO:0005826 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.1 0.4 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 1.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.6 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0001939 female pronucleus(GO:0001939)
0.0 1.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3 0.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.3 0.8 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.5 GO:0030984 kininogen binding(GO:0030984)
0.2 0.7 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.2 0.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 1.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.1 1.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.9 GO:0000150 recombinase activity(GO:0000150)
0.1 0.9 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 1.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0001227 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.6 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0008353 MAP kinase activity(GO:0004707) RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.9 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.9 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.5 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.9 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.7 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.0 0.3 PID_CONE_PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.9 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME_P38MAPK_EVENTS Genes involved in p38MAPK events
0.0 0.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta