Motif ID: AGCCCUU

Z-value: 0.355


Mature miRNA associated with seed AGCCCUU:

NamemiRBase Accession
hsa-miR-129-1-3p MIMAT0004548
hsa-miR-129-2-3p MIMAT0004605



Activity profile for motif AGCCCUU.

activity profile for motif AGCCCUU


Sorted Z-values histogram for motif AGCCCUU

Sorted Z-values for motif AGCCCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCCCUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_100238956 1.130 ENST00000231461.5
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr5_-_137368708 0.696 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr3_+_179370517 0.632 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr17_+_55333876 0.556 ENST00000284073.2
MSI2
musashi RNA-binding protein 2
chr10_-_62704005 0.480 ENST00000337910.5
RHOBTB1
Rho-related BTB domain containing 1
chr16_+_28303804 0.468 ENST00000341901.4
SBK1
SH3 domain binding kinase 1
chrX_-_117250740 0.468 ENST00000371882.1
ENST00000540167.1
ENST00000545703.1
KLHL13


kelch-like family member 13


chr10_-_116286656 0.386 ENST00000428430.1
ENST00000369266.3
ENST00000392952.3
ABLIM1


actin binding LIM protein 1


chr12_-_56652111 0.378 ENST00000267116.7
ANKRD52
ankyrin repeat domain 52
chr14_+_101193164 0.374 ENST00000341267.4
DLK1
delta-like 1 homolog (Drosophila)
chr18_-_74207146 0.371 ENST00000443185.2
ZNF516
zinc finger protein 516
chr1_+_61547894 0.348 ENST00000403491.3
NFIA
nuclear factor I/A
chr22_+_29279552 0.347 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr15_-_48470558 0.346 ENST00000324324.7
MYEF2
myelin expression factor 2
chr3_-_114790179 0.332 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr8_+_104152922 0.328 ENST00000309982.5
ENST00000438105.2
ENST00000297574.6
BAALC


brain and acute leukemia, cytoplasmic


chr16_+_69599861 0.313 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr4_-_39640700 0.303 ENST00000295958.5
SMIM14
small integral membrane protein 14
chr14_+_56585048 0.302 ENST00000267460.4
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr12_-_56224546 0.276 ENST00000357606.3
ENST00000547445.1
DNAJC14

DnaJ (Hsp40) homolog, subfamily C, member 14


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.6 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.5 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.1 0.2 GO:2000053 Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.2 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.2 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.0 0.2 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 0.6 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle