Motif ID: AGCAGCG

Z-value: 0.281


Mature miRNA associated with seed AGCAGCG:

NamemiRBase Accession
hsa-miR-503-5p MIMAT0002874



Activity profile for motif AGCAGCG.

activity profile for motif AGCAGCG


Sorted Z-values histogram for motif AGCAGCG

Sorted Z-values for motif AGCAGCG



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCAGCG

PNG image of the network

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Top targets:


Showing 1 to 20 of 181 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_68165657 0.611 ENST00000243457.3
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr12_-_63328817 0.593 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr5_+_140254884 0.542 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr5_+_140227048 0.535 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr5_+_140248518 0.530 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr1_-_22469459 0.525 ENST00000290167.6
WNT4
wingless-type MMTV integration site family, member 4
chr5_+_140213815 0.515 ENST00000525929.1
ENST00000378125.3
PCDHA7

protocadherin alpha 7

chr5_+_140220769 0.506 ENST00000531613.1
ENST00000378123.3
PCDHA8

protocadherin alpha 8

chr19_-_14316980 0.470 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr5_+_42423872 0.412 ENST00000230882.4
ENST00000357703.3
GHR

growth hormone receptor

chr6_-_134639180 0.355 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr16_+_58549378 0.322 ENST00000310682.2
ENST00000394266.4
ENST00000219315.4
SETD6


SET domain containing 6


chr6_+_135502466 0.313 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr5_+_140207536 0.291 ENST00000529310.1
ENST00000527624.1
PCDHA6

protocadherin alpha 6

chr5_+_140345820 0.288 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr5_+_140306478 0.282 ENST00000253807.2
PCDHAC1
protocadherin alpha subfamily C, 1
chr5_+_140165876 0.268 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1


protocadherin alpha 1


chr9_-_3525968 0.249 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3


regulatory factor X, 3 (influences HLA class II expression)


chr5_+_140180635 0.237 ENST00000522353.2
ENST00000532566.2
PCDHA3

protocadherin alpha 3

chr5_+_140261703 0.225 ENST00000409494.1
ENST00000289272.2
PCDHA13

protocadherin alpha 13


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 0.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.2 0.5 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) renal vesicle induction(GO:0072034)
0.1 0.4 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.1 GO:0060067 cervix development(GO:0060067)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.4 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)

Gene overrepresentation in molecular_function category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling