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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR5A2

Z-value: 1.08

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Transcription factors associated with NR5A2

Gene Symbol Gene ID Gene Info
NR5A2
ENSG00000116833.9 nuclear receptor subfamily 5 group A member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR5A2hg19_v2_chr1_+_199996702_199996732-0.834.1e-02Click!

Activity profile of NR5A2 motif

Sorted Z-values of NR5A2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_27806117 1.01 ENST00000330180.2
HIST1H2AK
histone cluster 1, H2ak
chr21_+_33671264 0.98 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr6_-_26235206 0.93 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr16_-_67224002 0.85 ENST00000563889.1
ENST00000564418.1
ENST00000545725.2
ENST00000314586.6
EXOC3L1
exocyst complex component 3-like 1
chr17_-_67323385 0.75 ENST00000588665.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr19_+_2249308 0.65 ENST00000592877.1
ENST00000221496.4
AMH
anti-Mullerian hormone
chr4_-_185776854 0.63 ENST00000511703.1
RP11-701P16.5
RP11-701P16.5
chr8_+_94752349 0.61 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr17_-_73844722 0.56 ENST00000586257.1
WBP2
WW domain binding protein 2
chr4_-_170948361 0.54 ENST00000393702.3
MFAP3L
microfibrillar-associated protein 3-like
chr13_-_30160925 0.52 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr22_+_32149927 0.50 ENST00000437411.1
ENST00000535622.1
ENST00000536766.1
ENST00000400242.3
ENST00000266091.3
ENST00000400249.2
ENST00000400246.1
ENST00000382105.2
DEPDC5
DEP domain containing 5
chr4_-_170947485 0.49 ENST00000504999.1
MFAP3L
microfibrillar-associated protein 3-like
chr3_+_167582561 0.47 ENST00000463642.1
ENST00000464514.1
RP11-298O21.6
RP11-298O21.7
RP11-298O21.6
RP11-298O21.7
chr12_+_54384370 0.44 ENST00000504315.1
HOXC6
homeobox C6
chr17_+_74536115 0.42 ENST00000592014.1
PRCD
progressive rod-cone degeneration
chr13_-_24476794 0.42 ENST00000382140.2
C1QTNF9B
C1q and tumor necrosis factor related protein 9B
chr16_+_28875126 0.42 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr18_-_44500101 0.41 ENST00000589917.1
ENST00000587810.1
PIAS2
protein inhibitor of activated STAT, 2
chr6_+_27806319 0.40 ENST00000606613.1
ENST00000396980.3
HIST1H2BN
histone cluster 1, H2bn
chr9_-_131872928 0.40 ENST00000455830.2
ENST00000393384.3
ENST00000318080.2
CRAT
carnitine O-acetyltransferase
chr1_+_149858461 0.39 ENST00000331380.2
HIST2H2AC
histone cluster 2, H2ac
chr5_+_175085033 0.39 ENST00000377291.2
HRH2
histamine receptor H2
chr16_-_2581409 0.38 ENST00000567119.1
ENST00000565480.1
ENST00000382350.1
CEMP1
cementum protein 1
chr3_-_187455680 0.38 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr8_-_145550337 0.38 ENST00000531896.1
DGAT1
diacylglycerol O-acyltransferase 1
chr15_+_59730348 0.38 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr2_+_7118755 0.37 ENST00000433456.1
RNF144A
ring finger protein 144A
chr9_+_131873227 0.37 ENST00000358994.4
ENST00000455292.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr5_-_159766528 0.37 ENST00000505287.2
CCNJL
cyclin J-like
chr1_-_2323140 0.37 ENST00000378531.3
ENST00000378529.3
MORN1
MORN repeat containing 1
chr22_+_46546406 0.36 ENST00000440343.1
ENST00000415785.1
PPARA
peroxisome proliferator-activated receptor alpha
chr8_+_9009202 0.36 ENST00000518496.1
RP11-10A14.4
Uncharacterized protein
chr17_+_75316336 0.35 ENST00000591934.1
SEPT9
septin 9
chr20_-_44007014 0.34 ENST00000372726.3
ENST00000537995.1
TP53TG5
TP53 target 5
chr7_-_7782204 0.34 ENST00000418534.2
AC007161.5
AC007161.5
chr9_+_132096166 0.34 ENST00000436710.1
RP11-65J3.1
RP11-65J3.1
chr19_-_6057282 0.34 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr3_+_51705844 0.34 ENST00000457927.1
ENST00000444233.1
TEX264
testis expressed 264
chr20_-_48532019 0.33 ENST00000289431.5
SPATA2
spermatogenesis associated 2
chr9_-_130712995 0.33 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr6_-_26250835 0.33 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr6_-_27100529 0.33 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ
histone cluster 1, H2bj
chr19_+_36134528 0.32 ENST00000591135.1
ETV2
ets variant 2
chr15_-_91475706 0.32 ENST00000561036.1
HDDC3
HD domain containing 3
chrX_+_22056165 0.32 ENST00000535894.1
PHEX
phosphate regulating endopeptidase homolog, X-linked
chrX_-_107225600 0.31 ENST00000302917.1
TEX13B
testis expressed 13B
chr4_+_124571409 0.31 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1
long intergenic non-protein coding RNA 1091
chr3_-_87039662 0.31 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr22_+_24322322 0.31 ENST00000215780.5
ENST00000402588.3
GSTT2
glutathione S-transferase theta 2
chr5_-_131879205 0.31 ENST00000231454.1
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr8_-_145018905 0.31 ENST00000398774.2
PLEC
plectin
chr10_-_76995675 0.31 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr1_-_146697185 0.30 ENST00000533174.1
ENST00000254090.4
FMO5
flavin containing monooxygenase 5
chr1_-_23504176 0.30 ENST00000302291.4
LUZP1
leucine zipper protein 1
chr6_+_116782527 0.30 ENST00000368606.3
ENST00000368605.1
FAM26F
family with sequence similarity 26, member F
chr6_-_27880174 0.30 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr1_-_20126365 0.29 ENST00000294543.6
ENST00000375122.2
TMCO4
transmembrane and coiled-coil domains 4
chr1_+_1260598 0.29 ENST00000488011.1
GLTPD1
glycolipid transfer protein domain containing 1
chr11_+_67798114 0.29 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NDUFS8
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr20_+_62666902 0.29 ENST00000431158.1
LINC00176
long intergenic non-protein coding RNA 176
chr6_+_134758827 0.28 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr6_+_26199737 0.28 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr11_-_65793948 0.28 ENST00000312106.5
CATSPER1
cation channel, sperm associated 1
chr19_+_10222189 0.27 ENST00000321826.4
P2RY11
purinergic receptor P2Y, G-protein coupled, 11
chr17_-_7832753 0.27 ENST00000303790.2
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr17_-_17485731 0.26 ENST00000395783.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr5_+_133859996 0.26 ENST00000512386.1
PHF15
jade family PHD finger 2
chr7_+_76107444 0.26 ENST00000435861.1
DTX2
deltex homolog 2 (Drosophila)
chr9_-_34620440 0.26 ENST00000421919.1
ENST00000378911.3
ENST00000477738.2
ENST00000341694.2
ENST00000259632.7
ENST00000378913.2
ENST00000378916.4
ENST00000447983.2
DCTN3
dynactin 3 (p22)
chr14_-_102976135 0.26 ENST00000560748.1
ANKRD9
ankyrin repeat domain 9
chr3_+_39149145 0.26 ENST00000301819.6
ENST00000431162.2
TTC21A
tetratricopeptide repeat domain 21A
chr10_+_695888 0.26 ENST00000441152.2
PRR26
proline rich 26
chr17_-_27503770 0.26 ENST00000533112.1
MYO18A
myosin XVIIIA
chr8_+_74271144 0.26 ENST00000519134.1
ENST00000518355.1
RP11-434I12.3
RP11-434I12.3
chr7_-_150777920 0.25 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chrX_-_63005405 0.25 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr16_+_28996572 0.25 ENST00000360872.5
ENST00000566177.1
ENST00000354453.4
LAT
linker for activation of T cells
chr6_+_30856507 0.25 ENST00000513240.1
ENST00000424544.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr10_-_94003003 0.25 ENST00000412050.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr22_+_29702996 0.25 ENST00000406549.3
ENST00000360113.2
ENST00000341313.6
ENST00000403764.1
ENST00000471961.1
ENST00000407854.1
GAS2L1
growth arrest-specific 2 like 1
chrX_+_47083037 0.25 ENST00000523034.1
CDK16
cyclin-dependent kinase 16
chr11_+_126139005 0.25 ENST00000263578.5
ENST00000442061.2
ENST00000532125.1
FOXRED1
FAD-dependent oxidoreductase domain containing 1
chr15_+_41952591 0.25 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA
MGA, MAX dimerization protein
chr1_-_183538319 0.25 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr22_+_31518938 0.25 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr12_-_49319265 0.24 ENST00000552878.1
ENST00000453172.2
FKBP11
FK506 binding protein 11, 19 kDa
chr16_-_4588469 0.24 ENST00000588381.1
ENST00000563332.2
CDIP1
cell death-inducing p53 target 1
chr19_-_50311896 0.24 ENST00000529634.2
FUZ
fuzzy planar cell polarity protein
chr8_+_145149930 0.24 ENST00000318911.4
CYC1
cytochrome c-1
chr15_-_78112553 0.24 ENST00000562933.1
LINGO1
leucine rich repeat and Ig domain containing 1
chr14_-_102976091 0.24 ENST00000286918.4
ANKRD9
ankyrin repeat domain 9
chr19_+_50191921 0.24 ENST00000420022.3
ADM5
adrenomedullin 5 (putative)
chrX_-_55020511 0.24 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr12_+_133067157 0.24 ENST00000261673.6
FBRSL1
fibrosin-like 1
chr6_+_31939608 0.24 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr11_-_6341724 0.24 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr1_-_153538011 0.23 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr17_-_8066843 0.23 ENST00000404970.3
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr7_-_150777949 0.23 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr19_+_11350278 0.23 ENST00000252453.8
C19orf80
chromosome 19 open reading frame 80
chr2_-_96926313 0.23 ENST00000435268.1
TMEM127
transmembrane protein 127
chr20_+_32077880 0.23 ENST00000342704.6
ENST00000375279.2
CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr8_+_21911054 0.22 ENST00000519850.1
ENST00000381470.3
DMTN
dematin actin binding protein
chr17_-_7991021 0.22 ENST00000319144.4
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chr6_+_157099036 0.22 ENST00000350026.5
ENST00000346085.5
ENST00000367148.1
ENST00000275248.4
ARID1B
AT rich interactive domain 1B (SWI1-like)
chr22_-_28490123 0.22 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr3_-_125775629 0.22 ENST00000383598.2
SLC41A3
solute carrier family 41, member 3
chr6_-_85473073 0.22 ENST00000606621.1
TBX18
T-box 18
chr17_-_18945798 0.22 ENST00000395635.1
GRAP
GRB2-related adaptor protein
chr10_-_76995769 0.22 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr2_+_113479063 0.22 ENST00000327581.4
NT5DC4
5'-nucleotidase domain containing 4
chr3_+_51705222 0.22 ENST00000457573.1
ENST00000341333.5
ENST00000412249.1
ENST00000425781.1
ENST00000415259.1
ENST00000395057.1
ENST00000416589.1
TEX264
testis expressed 264
chr12_+_52056548 0.22 ENST00000545061.1
ENST00000355133.3
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr8_-_145018080 0.22 ENST00000354589.3
PLEC
plectin
chr19_+_5623186 0.22 ENST00000538656.1
SAFB
scaffold attachment factor B
chr19_-_39826639 0.21 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG
glia maturation factor, gamma
chr7_+_5465382 0.21 ENST00000609130.1
RP11-1275H24.2
RP11-1275H24.2
chr9_+_131873659 0.21 ENST00000452489.2
ENST00000347048.4
ENST00000357197.4
ENST00000445241.1
ENST00000355007.3
ENST00000414331.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr12_+_53818855 0.21 ENST00000550839.1
AMHR2
anti-Mullerian hormone receptor, type II
chr2_-_220119280 0.21 ENST00000392088.2
TUBA4A
tubulin, alpha 4a
chr8_+_67405794 0.21 ENST00000522977.1
ENST00000480005.1
C8orf46
chromosome 8 open reading frame 46
chr20_+_1875942 0.21 ENST00000358771.4
SIRPA
signal-regulatory protein alpha
chr1_+_145301735 0.21 ENST00000605176.1
NBPF10
neuroblastoma breakpoint family, member 10
chr2_-_31361543 0.21 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr10_+_74653330 0.21 ENST00000334011.5
OIT3
oncoprotein induced transcript 3
chr1_+_206579736 0.21 ENST00000439126.1
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr2_+_7005959 0.21 ENST00000442639.1
RSAD2
radical S-adenosyl methionine domain containing 2
chrX_+_70364667 0.21 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr9_+_131873591 0.20 ENST00000393370.2
ENST00000337738.1
ENST00000348141.5
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr19_+_1248547 0.20 ENST00000586757.1
ENST00000300952.2
MIDN
midnolin
chr16_+_4674787 0.20 ENST00000262370.7
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chrX_+_48620147 0.20 ENST00000303227.6
GLOD5
glyoxalase domain containing 5
chrX_-_49056635 0.20 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
SYP
synaptophysin
chr7_+_39773160 0.20 ENST00000340510.4
LINC00265
long intergenic non-protein coding RNA 265
chr17_-_73663245 0.20 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr17_+_73089382 0.20 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr6_-_34360413 0.20 ENST00000607016.1
NUDT3
nudix (nucleoside diphosphate linked moiety X)-type motif 3
chr4_+_184826418 0.20 ENST00000308497.4
ENST00000438269.1
STOX2
storkhead box 2
chr22_-_26879734 0.20 ENST00000422379.2
ENST00000336873.5
ENST00000398145.2
HPS4
Hermansky-Pudlak syndrome 4
chr10_+_104180580 0.20 ENST00000425536.1
FBXL15
F-box and leucine-rich repeat protein 15
chr12_+_120875910 0.20 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr17_+_900342 0.20 ENST00000327158.4
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr20_+_30865429 0.20 ENST00000375712.3
KIF3B
kinesin family member 3B
chr11_+_126262027 0.20 ENST00000526311.1
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr22_+_29702572 0.20 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
GAS2L1
growth arrest-specific 2 like 1
chr1_+_1447517 0.20 ENST00000378756.3
ENST00000378755.5
ATAD3A
ATPase family, AAA domain containing 3A
chr17_-_20370847 0.20 ENST00000423676.3
ENST00000324290.5
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr7_-_72437484 0.19 ENST00000395244.1
TRIM74
tripartite motif containing 74
chr5_+_176853702 0.19 ENST00000507633.1
ENST00000393576.3
ENST00000355958.5
ENST00000528793.1
ENST00000512684.1
GRK6
G protein-coupled receptor kinase 6
chr2_-_106054952 0.19 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr4_+_148402069 0.19 ENST00000358556.4
ENST00000339690.5
ENST00000511804.1
ENST00000324300.5
EDNRA
endothelin receptor type A
chr13_+_100634004 0.19 ENST00000376335.3
ZIC2
Zic family member 2
chr11_-_78052923 0.19 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr19_-_13044494 0.19 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr11_+_107461804 0.19 ENST00000531234.1
ELMOD1
ELMO/CED-12 domain containing 1
chrX_+_153029633 0.19 ENST00000538966.1
ENST00000361971.5
ENST00000538776.1
ENST00000538543.1
PLXNB3
plexin B3
chr11_+_66624527 0.19 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr20_+_1115821 0.19 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr3_-_178789220 0.19 ENST00000414084.1
ZMAT3
zinc finger, matrin-type 3
chr19_-_4517613 0.19 ENST00000301286.3
PLIN4
perilipin 4
chr17_+_7211656 0.19 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr5_+_71403061 0.19 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr16_+_2587998 0.19 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chr3_-_39149082 0.19 ENST00000427459.1
ENST00000411813.1
ENST00000422110.2
ENST00000479927.1
GORASP1
golgi reassembly stacking protein 1, 65kDa
chr17_+_36858694 0.19 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr22_+_38071615 0.19 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr6_-_72129806 0.19 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472
long intergenic non-protein coding RNA 472
chr15_-_74043816 0.18 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr11_+_73676281 0.18 ENST00000543947.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr16_+_28996416 0.18 ENST00000395456.2
ENST00000454369.2
LAT
linker for activation of T cells
chrX_+_49832231 0.18 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr2_-_128432639 0.18 ENST00000545738.2
ENST00000355119.4
ENST00000409808.2
LIMS2
LIM and senescent cell antigen-like domains 2
chr9_+_131873842 0.18 ENST00000417728.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr2_+_191334212 0.18 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr3_-_122512619 0.18 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr1_-_160492994 0.18 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAMF6
SLAM family member 6
chr9_+_132388566 0.18 ENST00000372480.1
NTMT1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr12_-_111395610 0.18 ENST00000548329.1
ENST00000546852.1
RP1-46F2.3
RP1-46F2.3
chr19_+_42381337 0.18 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr11_+_63742050 0.18 ENST00000314133.3
ENST00000535431.1
COX8A
AP000721.4
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr20_-_36156264 0.18 ENST00000445723.1
ENST00000414080.1
BLCAP
bladder cancer associated protein
chr19_+_46850251 0.18 ENST00000012443.4
PPP5C
protein phosphatase 5, catalytic subunit
chr10_-_88729200 0.18 ENST00000474994.2
MMRN2
multimerin 2
chr6_-_85473156 0.18 ENST00000606784.1
ENST00000606325.1
TBX18
T-box 18
chr5_+_179233376 0.18 ENST00000376929.3
ENST00000514093.1
SQSTM1
sequestosome 1
chr10_+_85954377 0.17 ENST00000332904.3
ENST00000372117.3
CDHR1
cadherin-related family member 1
chr16_+_4674814 0.17 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr9_+_33240157 0.17 ENST00000379721.3
SPINK4
serine peptidase inhibitor, Kazal type 4
chr7_+_150782945 0.17 ENST00000463381.1
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr19_+_589893 0.17 ENST00000251287.2
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr17_-_46682321 0.17 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chr3_+_9958758 0.17 ENST00000383812.4
ENST00000438091.1
ENST00000295981.3
ENST00000436503.1
ENST00000403601.3
ENST00000416074.2
ENST00000455057.1
IL17RC
interleukin 17 receptor C
chr19_-_44259136 0.17 ENST00000270066.6
SMG9
SMG9 nonsense mediated mRNA decay factor
chr5_+_177540444 0.17 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr5_+_141016969 0.17 ENST00000518856.1
RELL2
RELT-like 2
chr20_-_3748363 0.17 ENST00000217195.8
C20orf27
chromosome 20 open reading frame 27
chr16_+_2820912 0.17 ENST00000570539.1
SRRM2
serine/arginine repetitive matrix 2
chr19_+_48773337 0.17 ENST00000595607.1
ZNF114
zinc finger protein 114
chr16_+_14805546 0.17 ENST00000552140.1
NPIPA3
nuclear pore complex interacting protein family, member A3

Network of associatons between targets according to the STRING database.

First level regulatory network of NR5A2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0007506 gonadal mesoderm development(GO:0007506)
0.2 0.5 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.4 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.5 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.4 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1 0.3 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.1 0.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.3 GO:0021503 neural fold bending(GO:0021503)
0.1 0.4 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.2 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.6 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.2 GO:0035623 renal glucose absorption(GO:0035623)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.3 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.2 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.1 0.5 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.3 GO:0030222 eosinophil differentiation(GO:0030222)
0.1 0.5 GO:0043308 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.1 0.2 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.2 GO:0009386 translational attenuation(GO:0009386)
0.1 0.2 GO:0018194 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.1 0.3 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.1 0.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.4 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.2 GO:0032900 negative regulation of neurotrophin production(GO:0032900)
0.0 0.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.8 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.3 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.2 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.3 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.2 GO:1903299 regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317) response to isolation stress(GO:0035900)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.1 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:0060922 cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.0 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.3 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.5 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.1 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.2 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.2 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.4 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0071318 neuronal signal transduction(GO:0023041) cellular response to ATP(GO:0071318)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.0 GO:0035565 regulation of pronephros size(GO:0035565)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:2000330 positive regulation of activation of Janus kinase activity(GO:0010536) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.0 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0070458 establishment of blood-nerve barrier(GO:0008065) cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.0 GO:1902822 cleavage furrow ingression(GO:0036090) regulation of late endosome to lysosome transport(GO:1902822) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.2 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.6 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.1 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.3 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.0 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.0 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.0 GO:0072034 renal vesicle induction(GO:0072034)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0031335 cellular response to phosphate starvation(GO:0016036) regulation of sulfur amino acid metabolic process(GO:0031335) positive regulation of sulfur amino acid metabolic process(GO:0031337) regulation of homocysteine metabolic process(GO:0050666) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.0 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.0 0.1 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510) regulation of DNA catabolic process(GO:1903624)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.5 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0016939 plus-end kinesin complex(GO:0005873) kinesin II complex(GO:0016939)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0044753 amphisome(GO:0044753)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.5 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.2 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0070470 plasma membrane respiratory chain(GO:0070470)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.0 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.4 GO:0031105 septin complex(GO:0031105)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.0 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 0.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.2 0.5 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 0.5 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 0.3 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.3 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.5 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.3 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.4 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.2 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.2 GO:0030395 lactose binding(GO:0030395)
0.1 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.4 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.5 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.2 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.3 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.1 GO:0008443 phosphofructokinase activity(GO:0008443)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.0 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 1.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.0 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins