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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXB13

Z-value: 0.41

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Transcription factors associated with HOXB13

Gene Symbol Gene ID Gene Info
ENSG00000159184.7 HOXB13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB13hg19_v2_chr17_-_46806540_468065580.236.6e-01Click!

Activity profile of HOXB13 motif

Sorted Z-values of HOXB13 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB13

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_35634146 0.36 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD7
FXYD domain containing ion transport regulator 7
chr17_-_39538550 0.24 ENST00000394001.1
KRT34
keratin 34
chr5_-_157161727 0.23 ENST00000599823.1
AC026407.1
Uncharacterized protein
chr4_+_169575875 0.19 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr3_-_114790179 0.19 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr4_+_110749143 0.16 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr17_-_73663245 0.16 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr8_+_77593448 0.14 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr8_+_119294456 0.14 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr7_+_132937820 0.11 ENST00000393161.2
ENST00000253861.4
EXOC4
exocyst complex component 4
chr2_-_69180083 0.11 ENST00000328895.4
GKN2
gastrokine 2
chr5_-_159766528 0.11 ENST00000505287.2
CCNJL
cyclin J-like
chr8_+_77593474 0.11 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr16_-_71610985 0.10 ENST00000355962.4
TAT
tyrosine aminotransferase
chr1_-_149783914 0.10 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF
histone cluster 2, H2bf
chr17_-_73663168 0.10 ENST00000578201.1
ENST00000423245.2
RECQL5
RecQ protein-like 5
chr7_+_128784712 0.10 ENST00000289407.4
TSPAN33
tetraspanin 33
chr15_+_66994561 0.09 ENST00000288840.5
SMAD6
SMAD family member 6
chr1_-_54879140 0.09 ENST00000525990.1
SSBP3
single stranded DNA binding protein 3
chr15_-_55541227 0.09 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr11_+_118401706 0.09 ENST00000411589.2
ENST00000442938.2
ENST00000359862.4
TMEM25
transmembrane protein 25
chr16_+_30669720 0.08 ENST00000356166.6
FBRS
fibrosin
chr2_-_190044480 0.08 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr10_+_104005272 0.08 ENST00000369983.3
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr9_+_103947311 0.08 ENST00000395056.2
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr16_+_2205755 0.07 ENST00000326181.6
TRAF7
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
chr14_+_76776957 0.07 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr1_+_84630367 0.07 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_+_95972822 0.07 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr6_+_27782788 0.07 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr8_+_35649365 0.07 ENST00000437887.1
AC012215.1
Uncharacterized protein
chr9_+_20927764 0.06 ENST00000603044.1
ENST00000604254.1
FOCAD
focadhesin
chrX_+_115301975 0.06 ENST00000371906.4
AGTR2
angiotensin II receptor, type 2
chr1_+_23037323 0.06 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2
EPH receptor B2
chr22_-_38240412 0.06 ENST00000215941.4
ANKRD54
ankyrin repeat domain 54
chr16_-_24942411 0.06 ENST00000571843.1
ARHGAP17
Rho GTPase activating protein 17
chr16_-_24942273 0.05 ENST00000571406.1
ARHGAP17
Rho GTPase activating protein 17
chr3_-_195310802 0.05 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr12_+_70219052 0.05 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr11_+_63606373 0.05 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr22_-_38240316 0.05 ENST00000411961.2
ENST00000434930.1
ANKRD54
ankyrin repeat domain 54
chr19_-_5903714 0.05 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
AC024592.12
NDUFA11
FUT5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr2_+_74685413 0.04 ENST00000233615.2
WBP1
WW domain binding protein 1
chr5_-_145214848 0.04 ENST00000505416.1
ENST00000334744.4
ENST00000358004.2
ENST00000511435.1
PRELID2
PRELI domain containing 2
chr15_+_71839566 0.04 ENST00000357769.4
THSD4
thrombospondin, type I, domain containing 4
chr1_-_45956868 0.04 ENST00000451835.2
TESK2
testis-specific kinase 2
chr2_-_69180012 0.04 ENST00000481498.1
GKN2
gastrokine 2
chr9_-_104198042 0.04 ENST00000374855.4
ALDOB
aldolase B, fructose-bisphosphate
chr8_+_86376081 0.04 ENST00000285379.5
CA2
carbonic anhydrase II
chr9_-_130829588 0.04 ENST00000373078.4
NAIF1
nuclear apoptosis inducing factor 1
chr12_+_8309630 0.04 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr9_+_123884038 0.04 ENST00000373847.1
CNTRL
centriolin
chr6_-_43021612 0.04 ENST00000535468.1
CUL7
cullin 7
chr16_-_80926457 0.04 ENST00000563626.1
ENST00000562231.1
RP11-314O13.1
RP11-314O13.1
chr1_-_45956822 0.03 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chr1_-_45956800 0.03 ENST00000538496.1
TESK2
testis-specific kinase 2
chr7_-_130353553 0.03 ENST00000330992.7
ENST00000445977.2
COPG2
coatomer protein complex, subunit gamma 2
chr7_+_16700806 0.03 ENST00000446596.1
ENST00000438834.1
BZW2
basic leucine zipper and W2 domains 2
chr6_-_116833500 0.02 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr1_+_52682052 0.02 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr2_+_173724771 0.02 ENST00000538974.1
ENST00000540783.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr3_+_89156799 0.02 ENST00000452448.2
ENST00000494014.1
EPHA3
EPH receptor A3
chr12_-_52715179 0.02 ENST00000293670.3
KRT83
keratin 83
chr3_+_68053359 0.02 ENST00000478136.1
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chr16_-_2205352 0.02 ENST00000563192.1
RP11-304L19.5
RP11-304L19.5
chr2_+_74685527 0.02 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
WBP1
WW domain binding protein 1
chr11_-_102714534 0.02 ENST00000299855.5
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr19_+_1440838 0.02 ENST00000594262.1
AC027307.3
Uncharacterized protein
chr18_-_52989217 0.01 ENST00000570287.2
TCF4
transcription factor 4
chr1_+_84630574 0.01 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr9_-_14180778 0.01 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr19_+_56154913 0.01 ENST00000270451.5
ENST00000588537.1
ZNF581
zinc finger protein 581
chr13_-_45768841 0.01 ENST00000379108.1
KCTD4
potassium channel tetramerization domain containing 4
chr1_-_12679171 0.01 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr12_+_80838126 0.01 ENST00000266688.5
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chrM_+_12331 0.01 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr7_-_50860565 0.01 ENST00000403097.1
GRB10
growth factor receptor-bound protein 10
chr17_-_10560619 0.01 ENST00000583535.1
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
chr21_+_30672433 0.01 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr8_-_114449112 0.01 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr11_+_47279155 0.00 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr17_-_46806540 0.00 ENST00000290295.7
HOXB13
homeobox B13
chr7_-_11871815 0.00 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr1_-_36863481 0.00 ENST00000315732.2
LSM10
LSM10, U7 small nuclear RNA associated
chr17_+_18086392 0.00 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr1_+_84630352 0.00 ENST00000450730.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.1 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0035566 negative regulation of icosanoid secretion(GO:0032304) regulation of metanephros size(GO:0035566)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.0 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:2000035 regulation of stem cell division(GO:2000035)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:0070698 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME OPSINS Genes involved in Opsins