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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZKSCAN3

Z-value: 0.32

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Transcription factors associated with ZKSCAN3

Gene Symbol Gene ID Gene Info
ENSG00000189298.9 ZKSCAN3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZKSCAN3hg19_v2_chr6_+_28317685_28317761-0.147.9e-01Click!

Activity profile of ZKSCAN3 motif

Sorted Z-values of ZKSCAN3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_61244550 0.36 ENST00000421319.1
PUS10
pseudouridylate synthase 10
chr2_-_61244308 0.14 ENST00000407787.1
ENST00000398658.2
PUS10
pseudouridylate synthase 10
chr12_+_100867733 0.12 ENST00000546380.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr12_+_100867694 0.12 ENST00000392986.3
ENST00000549996.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr1_+_114473350 0.09 ENST00000503968.1
HIPK1
homeodomain interacting protein kinase 1
chr1_+_114472992 0.08 ENST00000514621.1
HIPK1
homeodomain interacting protein kinase 1
chr3_+_50316458 0.08 ENST00000316436.3
LSMEM2
leucine-rich single-pass membrane protein 2
chr2_+_191745560 0.08 ENST00000338435.4
GLS
glutaminase
chr22_-_28392227 0.07 ENST00000431039.1
TTC28
tetratricopeptide repeat domain 28
chr16_-_1429010 0.07 ENST00000513783.1
UNKL
unkempt family zinc finger-like
chr19_+_39759154 0.05 ENST00000331982.5
IFNL2
interferon, lambda 2
chr16_-_4039001 0.05 ENST00000576936.1
ADCY9
adenylate cyclase 9
chr1_-_935361 0.05 ENST00000484667.2
HES4
hes family bHLH transcription factor 4
chr5_-_65017921 0.05 ENST00000381007.4
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr7_-_155089251 0.05 ENST00000609974.1
AC144652.1
AC144652.1
chr7_+_155089486 0.04 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
INSIG1
insulin induced gene 1
chr2_-_167232484 0.04 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr5_-_95297534 0.04 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr2_+_191745535 0.04 ENST00000320717.3
GLS
glutaminase
chr7_-_37382683 0.04 ENST00000455879.1
ELMO1
engulfment and cell motility 1
chr1_+_226250379 0.04 ENST00000366815.3
ENST00000366814.3
H3F3A
H3 histone, family 3A
chr11_-_61062762 0.03 ENST00000335613.5
VWCE
von Willebrand factor C and EGF domains
chr19_-_4182530 0.03 ENST00000601571.1
ENST00000601488.1
ENST00000305232.6
ENST00000381935.3
ENST00000337491.2
SIRT6
sirtuin 6
chr1_-_115259337 0.03 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr19_-_49258606 0.03 ENST00000310160.3
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr11_+_66610883 0.03 ENST00000309657.3
ENST00000524506.1
RCE1
Ras converting CAAX endopeptidase 1
chr8_+_123793633 0.03 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr12_-_113573495 0.03 ENST00000446861.3
RASAL1
RAS protein activator like 1 (GAP1 like)
chr22_-_50312052 0.03 ENST00000330817.6
ALG12
ALG12, alpha-1,6-mannosyltransferase
chr7_+_155090271 0.02 ENST00000476756.1
INSIG1
insulin induced gene 1
chr17_-_62499334 0.02 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr19_-_39735646 0.02 ENST00000413851.2
IFNL3
interferon, lambda 3
chr14_-_80697396 0.02 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr6_-_35656712 0.02 ENST00000357266.4
ENST00000542713.1
FKBP5
FK506 binding protein 5
chr10_+_21823079 0.02 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr15_+_41624892 0.01 ENST00000260359.6
ENST00000450318.1
ENST00000450592.2
ENST00000559596.1
ENST00000414849.2
ENST00000560747.1
ENST00000560177.1
NUSAP1
nucleolar and spindle associated protein 1
chr19_+_54372639 0.01 ENST00000391769.2
MYADM
myeloid-associated differentiation marker
chr12_+_100867486 0.01 ENST00000548884.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr5_-_114598548 0.01 ENST00000379615.3
ENST00000419445.1
PGGT1B
protein geranylgeranyltransferase type I, beta subunit
chrX_+_153775869 0.01 ENST00000424839.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr3_-_122512619 0.01 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr10_+_6779326 0.01 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr3_-_10052849 0.01 ENST00000437616.1
ENST00000429065.2
AC022007.5
AC022007.5
chr15_+_74610894 0.01 ENST00000558821.1
ENST00000268082.4
CCDC33
coiled-coil domain containing 33
chr12_+_113796347 0.01 ENST00000545182.2
ENST00000280800.3
PLBD2
phospholipase B domain containing 2
chr1_+_93913665 0.01 ENST00000271234.7
ENST00000370256.4
ENST00000260506.8
FNBP1L
formin binding protein 1-like
chr1_-_28415204 0.01 ENST00000373871.3
EYA3
eyes absent homolog 3 (Drosophila)
chr17_+_36908984 0.01 ENST00000225426.4
ENST00000579088.1
PSMB3
proteasome (prosome, macropain) subunit, beta type, 3
chr21_+_39668831 0.01 ENST00000419868.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_+_66258846 0.00 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_+_21823243 0.00 ENST00000307729.7
ENST00000377091.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr16_-_745946 0.00 ENST00000562563.1
FBXL16
F-box and leucine-rich repeat protein 16
chr18_-_74728998 0.00 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP
myelin basic protein
chr7_+_150782945 0.00 ENST00000463381.1
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr1_-_28415075 0.00 ENST00000373863.3
ENST00000436342.2
ENST00000540618.1
ENST00000545175.1
EYA3
eyes absent homolog 3 (Drosophila)
chr9_+_124926856 0.00 ENST00000418632.1
MORN5
MORN repeat containing 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034255 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) positive regulation of chondrocyte proliferation(GO:1902732) histone H3-K9 deacetylation(GO:1990619)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.0 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)