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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXO3_FOXD2

Z-value: 0.66

Motif logo

Transcription factors associated with FOXO3_FOXD2

Gene Symbol Gene ID Gene Info
ENSG00000118689.10 FOXO3
ENSG00000186564.5 FOXD2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXD2hg19_v2_chr1_+_47901689_47901689-0.651.7e-01Click!
FOXO3hg19_v2_chr6_+_108977520_108977549-0.612.0e-01Click!

Activity profile of FOXO3_FOXD2 motif

Sorted Z-values of FOXO3_FOXD2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO3_FOXD2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_116654376 1.61 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr3_+_172468749 0.99 ENST00000366254.2
ENST00000415665.1
ENST00000438041.1
ECT2
epithelial cell transforming sequence 2 oncogene
chr5_+_40841410 0.84 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr6_-_32083106 0.83 ENST00000442721.1
TNXB
tenascin XB
chr8_+_31497271 0.77 ENST00000520407.1
NRG1
neuregulin 1
chr4_+_95174445 0.73 ENST00000509418.1
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr7_+_106809406 0.73 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1
HMG-box transcription factor 1
chr6_+_89791507 0.72 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr11_+_1151573 0.72 ENST00000534821.1
ENST00000356191.2
MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr4_+_76871883 0.68 ENST00000599764.1
AC110615.1
Uncharacterized protein
chr3_+_172468472 0.61 ENST00000232458.5
ENST00000392692.3
ECT2
epithelial cell transforming sequence 2 oncogene
chr3_+_172468505 0.60 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
ECT2
epithelial cell transforming sequence 2 oncogene
chr17_-_8059638 0.58 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1
period circadian clock 1
chr2_+_172309634 0.58 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr1_+_111682058 0.58 ENST00000545121.1
CEPT1
choline/ethanolamine phosphotransferase 1
chr7_-_95225768 0.57 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr5_+_78532003 0.54 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr10_-_98347063 0.53 ENST00000443638.1
TM9SF3
transmembrane 9 superfamily member 3
chr8_+_26150628 0.53 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr6_-_108278456 0.52 ENST00000429168.1
SEC63
SEC63 homolog (S. cerevisiae)
chr3_-_57233966 0.51 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr3_+_136649311 0.49 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr8_+_71485681 0.49 ENST00000391684.1
AC120194.1
AC120194.1
chr4_+_90032651 0.48 ENST00000603357.1
RP11-84C13.1
RP11-84C13.1
chr12_-_772901 0.47 ENST00000305108.4
NINJ2
ninjurin 2
chr14_-_58894223 0.46 ENST00000555593.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr3_-_148939598 0.45 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr15_+_96897466 0.44 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3
RP11-522B15.3
chr9_-_98269481 0.43 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
PTCH1
patched 1
chr1_+_207277590 0.43 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr14_-_58893832 0.42 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr2_+_28974489 0.41 ENST00000455580.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr1_+_84630574 0.41 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_152266604 0.41 ENST00000430328.2
RIF1
RAP1 interacting factor homolog (yeast)
chr11_+_46402482 0.41 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr2_+_152266392 0.41 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RIF1
RAP1 interacting factor homolog (yeast)
chr11_+_117049910 0.41 ENST00000431081.2
ENST00000524842.1
SIDT2
SID1 transmembrane family, member 2
chr1_+_120839412 0.40 ENST00000355228.4
FAM72B
family with sequence similarity 72, member B
chr2_+_198380763 0.40 ENST00000448447.2
ENST00000409360.1
MOB4
MOB family member 4, phocein
chr7_-_112579673 0.40 ENST00000432572.1
C7orf60
chromosome 7 open reading frame 60
chr14_-_65569244 0.40 ENST00000557277.1
ENST00000556892.1
MAX
MYC associated factor X
chr4_-_111120334 0.38 ENST00000503885.1
ELOVL6
ELOVL fatty acid elongase 6
chr15_+_63188009 0.38 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr7_-_81635106 0.38 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr4_-_164534657 0.38 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr2_+_196521845 0.38 ENST00000359634.5
ENST00000412905.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr2_+_161993465 0.38 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr7_-_140340576 0.38 ENST00000275884.6
ENST00000475837.1
DENND2A
DENN/MADD domain containing 2A
chr4_-_165305086 0.38 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr14_-_24584138 0.37 ENST00000558280.1
ENST00000561028.1
NRL
neural retina leucine zipper
chr20_+_62887139 0.36 ENST00000609764.1
PCMTD2
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr12_-_127630534 0.36 ENST00000535022.1
RP11-575F12.2
RP11-575F12.2
chr5_-_146833803 0.35 ENST00000512722.1
DPYSL3
dihydropyrimidinase-like 3
chr5_-_142782862 0.35 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_-_23288930 0.35 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_+_51026926 0.34 ENST00000557735.1
ATL1
atlastin GTPase 1
chr16_+_290181 0.34 ENST00000417499.1
ITFG3
integrin alpha FG-GAP repeat containing 3
chr17_-_39150385 0.34 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr17_+_9745786 0.34 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr1_-_201096312 0.34 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr14_-_58893876 0.34 ENST00000555097.1
ENST00000555404.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr15_-_52944231 0.34 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr8_-_40755333 0.33 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chr20_-_22559211 0.33 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr1_+_199996733 0.33 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr13_-_41240717 0.33 ENST00000379561.5
FOXO1
forkhead box O1
chr15_-_70994612 0.33 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr5_+_64920543 0.32 ENST00000399438.3
ENST00000510585.2
TRAPPC13
CTC-534A2.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr14_-_58894332 0.32 ENST00000395159.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr4_-_105416039 0.32 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr2_-_202298268 0.31 ENST00000440597.1
TRAK2
trafficking protein, kinesin binding 2
chr12_-_76462713 0.31 ENST00000552056.1
NAP1L1
nucleosome assembly protein 1-like 1
chr1_+_84630352 0.31 ENST00000450730.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_111120132 0.31 ENST00000506625.1
ELOVL6
ELOVL fatty acid elongase 6
chr17_-_7082668 0.31 ENST00000573083.1
ENST00000574388.1
ASGR1
asialoglycoprotein receptor 1
chrX_+_78003204 0.31 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chr10_-_4720333 0.30 ENST00000430998.2
LINC00704
long intergenic non-protein coding RNA 704
chr8_+_95908041 0.30 ENST00000396113.1
ENST00000519136.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr6_+_21666633 0.30 ENST00000606851.1
CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr6_+_135502501 0.30 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr8_+_86999516 0.30 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr1_+_198126093 0.30 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NEK7
NIMA-related kinase 7
chr1_-_1356628 0.30 ENST00000442470.1
ENST00000537107.1
ANKRD65
ankyrin repeat domain 65
chr6_+_88299833 0.30 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
ORC3
origin recognition complex, subunit 3
chr10_+_111985713 0.30 ENST00000239007.7
MXI1
MAX interactor 1, dimerization protein
chr18_-_53303123 0.30 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr14_-_102605983 0.29 ENST00000334701.7
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr12_-_31479045 0.28 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr3_+_158288942 0.28 ENST00000491767.1
ENST00000355893.5
MLF1
myeloid leukemia factor 1
chr10_+_31610064 0.28 ENST00000446923.2
ENST00000559476.1
ZEB1
zinc finger E-box binding homeobox 1
chr15_-_44828838 0.28 ENST00000560750.1
EIF3J-AS1
EIF3J antisense RNA 1 (head to head)
chr1_-_115259337 0.28 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr6_+_62284008 0.28 ENST00000544932.1
MTRNR2L9
MT-RNR2-like 9 (pseudogene)
chr2_-_152146385 0.28 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr3_+_148447887 0.27 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr14_+_71165292 0.27 ENST00000553682.1
RP6-65G23.1
RP6-65G23.1
chr12_-_102591604 0.27 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chrM_+_4431 0.27 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr12_-_42878101 0.27 ENST00000552108.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr2_+_105050794 0.27 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr8_-_93978216 0.26 ENST00000517751.1
ENST00000524107.1
TRIQK
triple QxxK/R motif containing
chr12_-_71551868 0.26 ENST00000247829.3
TSPAN8
tetraspanin 8
chr8_-_42358742 0.26 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr3_+_187930491 0.25 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr7_-_112579869 0.25 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr5_-_41510725 0.25 ENST00000328457.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr8_-_128231299 0.25 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr1_-_1356719 0.25 ENST00000520296.1
ANKRD65
ankyrin repeat domain 65
chr2_-_71454185 0.25 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr7_-_14028488 0.25 ENST00000405358.4
ETV1
ets variant 1
chr17_+_57642886 0.25 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr3_+_178866199 0.25 ENST00000263967.3
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr13_-_31038370 0.25 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr12_+_25348186 0.25 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYRM5
LYR motif containing 5
chr2_+_149402989 0.25 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr14_-_91526922 0.25 ENST00000418736.2
ENST00000261991.3
RPS6KA5
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr12_+_12764773 0.24 ENST00000228865.2
CREBL2
cAMP responsive element binding protein-like 2
chr7_-_130598059 0.24 ENST00000432045.2
MIR29B1
microRNA 29a
chr10_-_32217717 0.24 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
ARHGAP12
Rho GTPase activating protein 12
chr1_+_199996702 0.24 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr1_+_84629976 0.24 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_-_40755987 0.24 ENST00000337702.4
TTC33
tetratricopeptide repeat domain 33
chr8_+_52730143 0.23 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr6_+_74405501 0.23 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr2_+_42104692 0.23 ENST00000398796.2
ENST00000442214.1
AC104654.1
AC104654.1
chr3_+_187930719 0.23 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr9_-_88896977 0.23 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr6_+_74405804 0.23 ENST00000287097.5
CD109
CD109 molecule
chr14_+_58894103 0.23 ENST00000354386.6
ENST00000556134.1
KIAA0586
KIAA0586
chr2_-_27294500 0.23 ENST00000447619.1
ENST00000429985.1
ENST00000456793.1
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr3_+_138153451 0.22 ENST00000389567.4
ENST00000289135.4
ESYT3
extended synaptotagmin-like protein 3
chr13_+_50589390 0.22 ENST00000360473.4
ENST00000312942.1
KCNRG
potassium channel regulator
chr6_-_134638767 0.22 ENST00000524929.1
SGK1
serum/glucocorticoid regulated kinase 1
chr12_-_71551652 0.22 ENST00000546561.1
TSPAN8
tetraspanin 8
chr18_+_52258390 0.22 ENST00000321600.1
DYNAP
dynactin associated protein
chr7_+_30174574 0.22 ENST00000409688.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr4_+_74606223 0.22 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr2_+_189157536 0.22 ENST00000409580.1
ENST00000409637.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr2_+_64068844 0.22 ENST00000337130.5
UGP2
UDP-glucose pyrophosphorylase 2
chr3_-_129375556 0.22 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr14_+_32547434 0.21 ENST00000556191.1
ENST00000554090.1
ARHGAP5
Rho GTPase activating protein 5
chr21_+_30671690 0.21 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_-_191878681 0.21 ENST00000409465.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr14_-_65569186 0.21 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
MAX
MYC associated factor X
chr10_+_111985837 0.21 ENST00000393134.1
MXI1
MAX interactor 1, dimerization protein
chr5_+_72251857 0.21 ENST00000507345.2
ENST00000512348.1
ENST00000287761.6
FCHO2
FCH domain only 2
chr3_+_186330712 0.21 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr14_+_56127960 0.21 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chrX_+_123094369 0.21 ENST00000455404.1
ENST00000218089.9
STAG2
stromal antigen 2
chr8_-_33455268 0.21 ENST00000522982.1
DUSP26
dual specificity phosphatase 26 (putative)
chr9_-_3469181 0.20 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr7_+_91570240 0.20 ENST00000394564.1
AKAP9
A kinase (PRKA) anchor protein 9
chr2_+_161993412 0.20 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr17_-_26662464 0.20 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chrX_-_133792480 0.20 ENST00000359237.4
PLAC1
placenta-specific 1
chr5_+_65222500 0.20 ENST00000511297.1
ENST00000506030.1
ERBB2IP
erbb2 interacting protein
chr3_+_158288960 0.20 ENST00000484955.1
ENST00000359117.5
ENST00000498592.1
ENST00000477042.1
ENST00000471745.1
ENST00000469452.1
MLF1
myeloid leukemia factor 1
chrX_-_20237059 0.20 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr14_+_56127989 0.20 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr2_+_173955327 0.20 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr2_+_196440692 0.20 ENST00000458054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr8_+_86121448 0.20 ENST00000520225.1
E2F5
E2F transcription factor 5, p130-binding
chr12_-_48213735 0.20 ENST00000417902.1
ENST00000417107.1
HDAC7
histone deacetylase 7
chr8_-_117886563 0.20 ENST00000519837.1
ENST00000522699.1
RAD21
RAD21 homolog (S. pombe)
chr3_+_186158169 0.20 ENST00000435548.1
ENST00000421006.1
RP11-78H24.1
RP11-78H24.1
chr12_+_20963647 0.20 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr1_+_206138884 0.20 ENST00000341209.5
ENST00000607379.1
FAM72A
family with sequence similarity 72, member A
chr17_-_46657473 0.20 ENST00000332503.5
HOXB4
homeobox B4
chr15_-_35280426 0.20 ENST00000559564.1
ENST00000356321.4
ZNF770
zinc finger protein 770
chr18_+_9475585 0.20 ENST00000585015.1
RALBP1
ralA binding protein 1
chr1_+_24645807 0.19 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr17_-_6947225 0.19 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
SLC16A11
solute carrier family 16, member 11
chrX_+_591524 0.19 ENST00000554971.1
ENST00000381575.1
SHOX
short stature homeobox
chr2_+_170440844 0.19 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr14_-_35008861 0.19 ENST00000250454.3
EAPP
E2F-associated phosphoprotein
chr12_+_69202975 0.19 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr5_-_98262240 0.19 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr21_-_35899113 0.19 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr16_-_84150410 0.19 ENST00000569907.1
MBTPS1
membrane-bound transcription factor peptidase, site 1
chr11_+_111410998 0.19 ENST00000533999.1
LAYN
layilin
chr8_-_99954788 0.19 ENST00000523601.1
STK3
serine/threonine kinase 3
chr2_+_196521903 0.19 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr2_-_39347524 0.19 ENST00000395038.2
ENST00000402219.2
SOS1
son of sevenless homolog 1 (Drosophila)
chr9_-_88897426 0.18 ENST00000375991.4
ENST00000326094.4
ISCA1
iron-sulfur cluster assembly 1
chr18_-_73967160 0.18 ENST00000579714.1
RP11-94B19.7
RP11-94B19.7
chr15_-_99057551 0.18 ENST00000558256.1
FAM169B
family with sequence similarity 169, member B
chr7_+_30174426 0.18 ENST00000324453.8
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr10_+_63808970 0.18 ENST00000309334.5
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr2_+_33661382 0.18 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_+_144980954 0.18 ENST00000367525.3
UTRN
utrophin
chr3_+_158288999 0.18 ENST00000482628.1
ENST00000478894.2
ENST00000392822.3
ENST00000466246.1
MLF1
myeloid leukemia factor 1
chr21_+_17443521 0.18 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr2_+_163175394 0.18 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr5_+_32788945 0.18 ENST00000326958.1
AC026703.1
AC026703.1
chr21_+_30671189 0.18 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr3_-_135915401 0.18 ENST00000491050.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr3_+_122513642 0.18 ENST00000261038.5
DIRC2
disrupted in renal carcinoma 2
chr7_+_77469439 0.18 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr9_-_20382446 0.18 ENST00000380321.1
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr16_-_3422283 0.18 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.2 0.5 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.2 0.5 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 0.8 GO:0010157 response to chlorate(GO:0010157)
0.2 1.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.4 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.8 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.3 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 1.0 GO:0097338 response to clozapine(GO:0097338)
0.1 0.3 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 2.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.4 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.4 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.8 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.5 GO:0030421 defecation(GO:0030421)
0.1 0.3 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.2 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.7 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.6 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.3 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.2 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.2 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.1 0.2 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.3 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.3 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.6 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.5 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.0 0.4 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.3 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.6 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.3 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.4 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.3 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.2 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.3 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0061030 elastin metabolic process(GO:0051541) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.7 GO:0090177 establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.0 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.1 GO:0032431 positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.0 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0019676 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) ammonia assimilation cycle(GO:0019676) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:1903899 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.2 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.0 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.5 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.5 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.3 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.4 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.0 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.1 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0097149 centralspindlin complex(GO:0097149)
0.3 1.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.7 GO:0070701 mucus layer(GO:0070701)
0.1 0.3 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.8 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.9 GO:0001940 male pronucleus(GO:0001940)
0.1 0.6 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 1.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.6 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.0 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.7 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.6 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.8 GO:0005119 smoothened binding(GO:0005119)
0.1 0.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.3 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.3 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.4 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.4 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 1.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 2.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 1.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.6 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.1 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.0 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon