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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXL1

Z-value: 1.37

Motif logo

Transcription factors associated with FOXL1

Gene Symbol Gene ID Gene Info
ENSG00000176678.4 FOXL1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXL1hg19_v2_chr16_+_86612112_86612123-0.631.8e-01Click!

Activity profile of FOXL1 motif

Sorted Z-values of FOXL1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXL1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_95616933 2.40 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr14_+_61449197 1.45 ENST00000533744.2
SLC38A6
solute carrier family 38, member 6
chr2_+_187371440 1.40 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr12_+_20963647 1.20 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr9_-_125240235 1.14 ENST00000259357.2
OR1J1
olfactory receptor, family 1, subfamily J, member 1
chr12_+_20963632 0.94 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr2_+_38177575 0.93 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chr5_-_145483932 0.89 ENST00000311450.4
PLAC8L1
PLAC8-like 1
chr3_-_148939598 0.75 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr3_-_46068969 0.73 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr3_+_151531810 0.71 ENST00000232892.7
AADAC
arylacetamide deacetylase
chr19_+_20959098 0.70 ENST00000360204.5
ENST00000594534.1
ZNF66
zinc finger protein 66
chr7_-_81635106 0.69 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr21_+_38888740 0.65 ENST00000597817.1
AP001421.1
Uncharacterized protein
chr7_-_34978980 0.65 ENST00000428054.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr8_-_82598067 0.64 ENST00000523942.1
ENST00000522997.1
IMPA1
inositol(myo)-1(or 4)-monophosphatase 1
chr2_+_114163945 0.64 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr11_-_104916034 0.61 ENST00000528513.1
ENST00000375706.2
ENST00000375704.3
CARD16
caspase recruitment domain family, member 16
chr12_+_20968608 0.60 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr5_-_87516448 0.57 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr14_+_57671888 0.57 ENST00000391612.1
AL391152.1
AL391152.1
chr12_-_100486668 0.57 ENST00000550544.1
ENST00000551980.1
ENST00000548045.1
ENST00000545232.2
ENST00000551973.1
UHRF1BP1L
UHRF1 binding protein 1-like
chr17_-_64216748 0.56 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr4_+_76871883 0.56 ENST00000599764.1
AC110615.1
Uncharacterized protein
chr7_+_23210760 0.54 ENST00000366347.4
AC005082.1
Uncharacterized protein
chr15_+_49913201 0.52 ENST00000329873.5
ENST00000558653.1
ENST00000559164.1
ENST00000560632.1
ENST00000559405.1
ENST00000251250.6
DTWD1
DTW domain containing 1
chr9_-_69229650 0.51 ENST00000416428.1
CBWD6
COBW domain containing 6
chr3_+_186742464 0.51 ENST00000416235.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr7_+_116451100 0.51 ENST00000464223.1
ENST00000484325.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr2_+_29001711 0.51 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr8_+_71485681 0.50 ENST00000391684.1
AC120194.1
AC120194.1
chr19_-_44384291 0.48 ENST00000324394.6
ZNF404
zinc finger protein 404
chr1_+_225140372 0.47 ENST00000366848.1
ENST00000439375.2
DNAH14
dynein, axonemal, heavy chain 14
chr8_+_109455830 0.45 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr14_+_73563735 0.45 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr10_-_21186144 0.45 ENST00000377119.1
NEBL
nebulette
chr12_-_91546926 0.44 ENST00000550758.1
DCN
decorin
chr9_+_125273081 0.44 ENST00000335302.5
OR1J2
olfactory receptor, family 1, subfamily J, member 2
chr15_+_69373210 0.43 ENST00000435479.1
ENST00000559870.1
LINC00277
RP11-809H16.5
long intergenic non-protein coding RNA 277
RP11-809H16.5
chr13_+_28519343 0.42 ENST00000381026.3
ATP5EP2
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
chr4_+_123653807 0.42 ENST00000314218.3
ENST00000542236.1
BBS12
Bardet-Biedl syndrome 12
chr9_-_47314222 0.42 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2
AL953854.2
chr12_-_25801478 0.41 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1
intermediate filament tail domain containing 1
chr10_+_94594351 0.41 ENST00000371552.4
EXOC6
exocyst complex component 6
chr4_-_84035868 0.41 ENST00000426923.2
ENST00000509973.1
PLAC8
placenta-specific 8
chr15_+_23255242 0.41 ENST00000450802.3
GOLGA8I
golgin A8 family, member I
chr21_+_25801041 0.41 ENST00000453784.2
ENST00000423581.1
AP000476.1
AP000476.1
chr12_-_10588539 0.41 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
KLRC2
NKG2-E
killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chr7_+_64126535 0.40 ENST00000344930.3
ZNF107
zinc finger protein 107
chr13_+_37581115 0.40 ENST00000481013.1
EXOSC8
exosome component 8
chr3_-_114035026 0.40 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr4_+_95128748 0.40 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_+_131571535 0.40 ENST00000474850.2
AKAP7
A kinase (PRKA) anchor protein 7
chr4_-_159080806 0.40 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr2_-_151344172 0.40 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr1_-_31902614 0.39 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chr15_+_35270552 0.38 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr4_+_78804393 0.37 ENST00000502384.1
MRPL1
mitochondrial ribosomal protein L1
chr6_+_168434678 0.37 ENST00000496008.1
KIF25
kinesin family member 25
chr6_-_106773291 0.37 ENST00000343245.3
ATG5
autophagy related 5
chr17_+_61151306 0.36 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chrX_-_138914394 0.36 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C
ATPase, class VI, type 11C
chr4_+_141264597 0.36 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr10_+_62538089 0.36 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr7_-_8302207 0.36 ENST00000407906.1
ICA1
islet cell autoantigen 1, 69kDa
chr2_+_172309634 0.36 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr5_+_115420688 0.36 ENST00000274458.4
COMMD10
COMM domain containing 10
chr14_+_85994943 0.35 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr4_-_112993808 0.35 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr2_-_188419078 0.35 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr1_+_219347203 0.35 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr1_-_100643765 0.34 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
LRRC39
leucine rich repeat containing 39
chr2_-_74007095 0.34 ENST00000452812.1
DUSP11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr1_-_163172625 0.33 ENST00000527988.1
ENST00000531476.1
ENST00000530507.1
RGS5
regulator of G-protein signaling 5
chr7_-_108209897 0.33 ENST00000313516.5
THAP5
THAP domain containing 5
chr4_+_78829479 0.33 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr3_+_187930719 0.33 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr15_-_80695917 0.33 ENST00000559008.1
RP11-210M15.2
Uncharacterized protein
chr3_-_155011483 0.32 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr1_+_104615595 0.32 ENST00000418362.1
RP11-364B6.1
RP11-364B6.1
chr4_+_166248775 0.32 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
MSMO1
methylsterol monooxygenase 1
chr22_+_23243156 0.32 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr21_+_17214724 0.32 ENST00000449491.1
USP25
ubiquitin specific peptidase 25
chr7_+_94536514 0.32 ENST00000413325.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr3_+_151531859 0.31 ENST00000488869.1
AADAC
arylacetamide deacetylase
chrM_+_8366 0.31 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chr6_-_114194483 0.30 ENST00000434296.2
RP1-249H1.4
RP1-249H1.4
chr8_+_52730143 0.30 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr4_+_9446156 0.30 ENST00000334879.1
DEFB131
defensin, beta 131
chr1_+_78470530 0.30 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr2_-_170681324 0.30 ENST00000409340.1
METTL5
methyltransferase like 5
chr2_-_99797390 0.30 ENST00000422537.2
MITD1
MIT, microtubule interacting and transport, domain containing 1
chr1_-_227505289 0.30 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr6_-_56492816 0.30 ENST00000522360.1
DST
dystonin
chr2_-_206950781 0.30 ENST00000403263.1
INO80D
INO80 complex subunit D
chrM_+_10464 0.29 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr1_+_219347186 0.29 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr17_-_67264947 0.29 ENST00000586811.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr12_-_100656134 0.29 ENST00000548313.1
DEPDC4
DEP domain containing 4
chr2_-_228497888 0.29 ENST00000264387.4
ENST00000409066.1
C2orf83
chromosome 2 open reading frame 83
chr1_+_152178320 0.29 ENST00000429352.1
RP11-107M16.2
RP11-107M16.2
chr2_-_170430277 0.29 ENST00000438035.1
ENST00000453929.2
FASTKD1
FAST kinase domains 1
chr5_-_43412418 0.29 ENST00000537013.1
ENST00000361115.4
CCL28
chemokine (C-C motif) ligand 28
chr6_+_76599809 0.28 ENST00000430435.1
MYO6
myosin VI
chr10_+_1102303 0.28 ENST00000381329.1
WDR37
WD repeat domain 37
chr3_-_185641681 0.28 ENST00000259043.7
TRA2B
transformer 2 beta homolog (Drosophila)
chr2_+_161993465 0.28 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr7_-_112430647 0.28 ENST00000312814.6
TMEM168
transmembrane protein 168
chr6_+_76330355 0.28 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr2_+_109403193 0.28 ENST00000412964.2
ENST00000295124.4
CCDC138
coiled-coil domain containing 138
chr12_-_10978957 0.28 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr6_-_88038996 0.28 ENST00000525899.1
GJB7
gap junction protein, beta 7, 25kDa
chr14_-_82089405 0.28 ENST00000554211.1
RP11-799P8.1
RP11-799P8.1
chr2_-_55459294 0.28 ENST00000407122.1
ENST00000406437.2
CLHC1
clathrin heavy chain linker domain containing 1
chr10_-_69597828 0.27 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr8_+_38831683 0.27 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr3_-_93747425 0.27 ENST00000315099.2
STX19
syntaxin 19
chr14_-_107283278 0.27 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr5_-_60240858 0.27 ENST00000426742.2
ENST00000265038.5
ENST00000543101.1
ENST00000439176.1
ERCC8
excision repair cross-complementing rodent repair deficiency, complementation group 8
chr12_-_68696652 0.26 ENST00000539972.1
MDM1
Mdm1 nuclear protein homolog (mouse)
chr4_-_85771168 0.26 ENST00000514071.1
WDFY3
WD repeat and FYVE domain containing 3
chr19_-_20748614 0.26 ENST00000596797.1
ZNF737
zinc finger protein 737
chr2_-_68547019 0.26 ENST00000409862.1
CNRIP1
cannabinoid receptor interacting protein 1
chr2_-_68547061 0.26 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chr18_-_69246167 0.26 ENST00000566582.1
RP11-510D19.1
RP11-510D19.1
chr1_+_186265399 0.26 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr22_+_42475692 0.26 ENST00000331479.3
SMDT1
single-pass membrane protein with aspartate-rich tail 1
chr2_+_64069459 0.25 ENST00000445915.2
ENST00000475462.1
UGP2
UDP-glucose pyrophosphorylase 2
chr14_+_45605157 0.25 ENST00000542564.2
FANCM
Fanconi anemia, complementation group M
chr13_+_28813645 0.25 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr15_+_49913175 0.25 ENST00000403028.3
DTWD1
DTW domain containing 1
chr1_-_86848760 0.25 ENST00000460698.2
ODF2L
outer dense fiber of sperm tails 2-like
chr5_+_39105358 0.25 ENST00000593965.1
AC008964.1
AC008964.1
chr1_+_196621002 0.25 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr6_+_153552455 0.25 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr2_+_183989157 0.25 ENST00000541912.1
NUP35
nucleoporin 35kDa
chr14_-_77889860 0.25 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1
chr19_+_11877838 0.25 ENST00000357901.4
ENST00000454339.2
ZNF441
zinc finger protein 441
chr9_-_70488865 0.25 ENST00000377392.5
CBWD5
COBW domain containing 5
chrX_-_139866723 0.25 ENST00000370532.2
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr8_-_25281747 0.25 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr1_-_145827015 0.25 ENST00000534502.1
ENST00000313835.9
ENST00000454423.3
GPR89A
G protein-coupled receptor 89A
chr6_-_38670897 0.25 ENST00000373365.4
GLO1
glyoxalase I
chr12_+_102513950 0.24 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP
PARP1 binding protein
chr21_-_19858196 0.24 ENST00000422787.1
TMPRSS15
transmembrane protease, serine 15
chr8_+_97597148 0.24 ENST00000521590.1
SDC2
syndecan 2
chr3_+_44626359 0.24 ENST00000412641.1
ZNF197
zinc finger protein 197
chr10_-_101989315 0.24 ENST00000370397.7
CHUK
conserved helix-loop-helix ubiquitous kinase
chr12_+_102514019 0.24 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARPBP
PARP1 binding protein
chr2_-_112237835 0.24 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr4_+_22999152 0.24 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr7_-_92463210 0.24 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr2_-_187367356 0.24 ENST00000595956.1
AC018867.2
AC018867.2
chr4_-_69536346 0.24 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr15_+_77713222 0.24 ENST00000558176.1
HMG20A
high mobility group 20A
chr3_-_98235962 0.23 ENST00000513873.1
CLDND1
claudin domain containing 1
chrM_+_8527 0.23 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr8_+_42911552 0.23 ENST00000525699.1
ENST00000529687.1
FNTA
farnesyltransferase, CAAX box, alpha
chr1_-_59012365 0.23 ENST00000456980.1
ENST00000482274.2
ENST00000453710.1
ENST00000419242.1
ENST00000358603.2
ENST00000371226.3
ENST00000426139.1
OMA1
OMA1 zinc metallopeptidase
chr2_-_188419200 0.23 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr4_-_164265984 0.23 ENST00000511901.1
NPY1R
neuropeptide Y receptor Y1
chr15_+_66797627 0.23 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr5_-_135290651 0.23 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr5_-_41794663 0.23 ENST00000510634.1
OXCT1
3-oxoacid CoA transferase 1
chr13_-_41837620 0.23 ENST00000379477.1
ENST00000452359.1
ENST00000379480.4
ENST00000430347.2
MTRF1
mitochondrial translational release factor 1
chr11_+_102980126 0.23 ENST00000375735.2
DYNC2H1
dynein, cytoplasmic 2, heavy chain 1
chr4_+_95128996 0.23 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_-_170430366 0.23 ENST00000453153.2
ENST00000445210.1
FASTKD1
FAST kinase domains 1
chr9_-_100707116 0.23 ENST00000259456.3
HEMGN
hemogen
chr3_+_99833755 0.23 ENST00000489081.1
CMSS1
cms1 ribosomal small subunit homolog (yeast)
chr6_+_63921351 0.22 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr8_-_90996459 0.22 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr1_-_207226313 0.22 ENST00000367084.1
YOD1
YOD1 deubiquitinase
chr1_+_156308403 0.22 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC
TSSK6 activating co-chaperone
chr11_+_112047087 0.22 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2
beta-carotene oxygenase 2
chr9_+_67968793 0.22 ENST00000417488.1
RP11-195B21.3
Protein LOC644249
chr6_-_90348440 0.22 ENST00000520441.1
ENST00000520318.1
ENST00000523377.1
LYRM2
LYR motif containing 2
chr7_+_99195878 0.22 ENST00000453227.1
ENST00000429679.1
GS1-259H13.2
GS1-259H13.2
chr15_+_63414760 0.22 ENST00000557972.1
LACTB
lactamase, beta
chr14_+_104177607 0.22 ENST00000429169.1
AL049840.1
Uncharacterized protein; cDNA FLJ53535
chr4_+_95174445 0.22 ENST00000509418.1
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr2_+_172544294 0.22 ENST00000358002.6
ENST00000435234.1
ENST00000443458.1
ENST00000412370.1
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2
chr22_+_18721427 0.22 ENST00000342888.3
AC008132.1
Uncharacterized protein
chr1_-_115301235 0.22 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr4_+_154073469 0.22 ENST00000441616.1
TRIM2
tripartite motif containing 2
chr2_-_190446738 0.22 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr11_-_112034831 0.22 ENST00000280357.7
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr10_-_30637906 0.22 ENST00000417581.1
MTPAP
mitochondrial poly(A) polymerase
chr2_-_14541060 0.22 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr8_+_107670064 0.22 ENST00000312046.6
OXR1
oxidation resistance 1
chr2_-_55237484 0.22 ENST00000394609.2
RTN4
reticulon 4
chrX_-_24045303 0.22 ENST00000328046.8
KLHL15
kelch-like family member 15
chr2_+_46769798 0.22 ENST00000238738.4
RHOQ
ras homolog family member Q
chr6_-_100016678 0.21 ENST00000523799.1
ENST00000520429.1
CCNC
cyclin C
chr8_+_107738343 0.21 ENST00000521592.1
OXR1
oxidation resistance 1
chrX_+_108779004 0.21 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr1_+_196621156 0.21 ENST00000359637.2
CFH
complement factor H
chr20_-_35274548 0.21 ENST00000262866.4
SLA2
Src-like-adaptor 2
chr2_-_150444300 0.21 ENST00000303319.5
MMADHC
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr1_+_207943667 0.21 ENST00000462968.2
CD46
CD46 molecule, complement regulatory protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 1.0 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.4 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.3 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.4 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.9 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.8 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.1 GO:0071042 nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.1 0.3 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.3 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.1 0.7 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.6 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.2 GO:1903414 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 0.6 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.5 GO:0008218 bioluminescence(GO:0008218)
0.1 0.5 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 2.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.6 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.1 0.4 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.7 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.6 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.3 GO:0019236 response to pheromone(GO:0019236)
0.1 0.2 GO:2000302 synaptic vesicle recycling via endosome(GO:0036466) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.8 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.1 0.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.1 0.2 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.1 0.2 GO:0035803 egg coat formation(GO:0035803)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.2 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.3 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 1.0 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.3 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 0.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.3 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.0 GO:0042704 uterine wall breakdown(GO:0042704)
0.0 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.4 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0050904 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.4 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:1902739 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.4 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.2 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.2 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.3 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.3 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0007398 ectoderm development(GO:0007398)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0043382 positive regulation of memory T cell differentiation(GO:0043382)
0.0 0.6 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0030728 ovulation(GO:0030728)
0.0 0.0 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.0 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:1904627 negative regulation of monocyte differentiation(GO:0045656) response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:0002543 activation of blood coagulation via clotting cascade(GO:0002543) phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0044346 fibroblast apoptotic process(GO:0044346)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.4 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.0 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:1902363 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.8 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.4 GO:1903204 negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.0 GO:0015882 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0014013 regulation of gliogenesis(GO:0014013)
0.0 0.0 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.0 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.0 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.0 GO:0042000 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0050821 protein stabilization(GO:0050821)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.4 GO:1990423 RZZ complex(GO:1990423)
0.1 0.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.2 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.7 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.1 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.2 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.4 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.5 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.5 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 1.2 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.2 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.5 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.4 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.6 GO:0031403 lithium ion binding(GO:0031403)
0.1 0.5 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.3 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 2.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.2 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.2 GO:0097689 iron channel activity(GO:0097689)
0.1 0.2 GO:0005549 odorant binding(GO:0005549)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.2 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.1 0.2 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.6 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.3 GO:0032557 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) pyrimidine ribonucleotide binding(GO:0032557) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 1.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192) tRNA guanylyltransferase activity(GO:0008193)
0.0 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.8 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.7 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.0 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.7 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.0 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.0 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID INSULIN PATHWAY Insulin Pathway
0.0 0.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID EPO PATHWAY EPO signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways