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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PRDM14

Z-value: 0.42

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Transcription factors associated with PRDM14

Gene Symbol Gene ID Gene Info
ENSG00000147596.3 PRDM14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM14hg19_v2_chr8_-_70983506_709835620.266.2e-01Click!

Activity profile of PRDM14 motif

Sorted Z-values of PRDM14 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM14

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_-_46692457 0.38 ENST00000468443.1
HOXB8
homeobox B8
chr4_+_141677577 0.32 ENST00000609937.1
RP11-102N12.3
RP11-102N12.3
chr5_-_108063949 0.23 ENST00000606054.1
LINC01023
long intergenic non-protein coding RNA 1023
chr11_+_62475130 0.23 ENST00000294117.5
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr8_+_101349823 0.23 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr17_-_46691990 0.18 ENST00000576562.1
HOXB8
homeobox B8
chr12_-_56326402 0.16 ENST00000547925.1
WIBG
within bgcn homolog (Drosophila)
chr17_-_46692287 0.16 ENST00000239144.4
HOXB8
homeobox B8
chr1_-_155006224 0.14 ENST00000368424.3
DCST2
DC-STAMP domain containing 2
chr1_-_155006254 0.13 ENST00000295536.5
DCST2
DC-STAMP domain containing 2
chr13_-_34250861 0.11 ENST00000445227.1
ENST00000454681.2
RP11-141M1.3
RP11-141M1.3
chr15_+_69850521 0.10 ENST00000558781.1
RP11-279F6.1
RP11-279F6.1
chr3_-_134092561 0.09 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2
angiomotin like 2
chr17_+_39994032 0.09 ENST00000293303.4
ENST00000438813.1
KLHL10
kelch-like family member 10
chr6_+_133561725 0.09 ENST00000452339.2
EYA4
eyes absent homolog 4 (Drosophila)
chr4_-_10459009 0.08 ENST00000507515.1
ZNF518B
zinc finger protein 518B
chr19_+_38880252 0.08 ENST00000586301.1
SPRED3
sprouty-related, EVH1 domain containing 3
chr15_-_45694380 0.08 ENST00000561148.1
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr11_-_46615498 0.08 ENST00000533727.1
ENST00000534300.1
ENST00000528950.1
ENST00000526606.1
AMBRA1
autophagy/beclin-1 regulator 1
chr9_+_132099158 0.08 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr1_-_42384343 0.07 ENST00000372584.1
HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr17_-_17485731 0.07 ENST00000395783.1
PEMT
phosphatidylethanolamine N-methyltransferase
chr5_+_32710736 0.07 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr2_-_145277882 0.07 ENST00000465070.1
ENST00000444559.1
ZEB2
zinc finger E-box binding homeobox 2
chr17_+_75450099 0.07 ENST00000586433.1
SEPT9
septin 9
chr11_-_62439727 0.06 ENST00000528862.1
C11orf48
chromosome 11 open reading frame 48
chr19_+_3572758 0.06 ENST00000416526.1
HMG20B
high mobility group 20B
chr12_-_49351228 0.05 ENST00000541959.1
ENST00000447318.2
ARF3
ADP-ribosylation factor 3
chr5_-_135528822 0.05 ENST00000607574.1
AC009014.3
AC009014.3
chr17_+_75450075 0.05 ENST00000592951.1
SEPT9
septin 9
chr1_+_156052354 0.05 ENST00000368301.2
LMNA
lamin A/C
chr1_+_39796810 0.05 ENST00000289893.4
MACF1
microtubule-actin crosslinking factor 1
chr10_+_12171636 0.05 ENST00000379051.1
ENST00000379033.3
ENST00000441368.1
ENST00000298428.9
ENST00000304267.8
SEC61A2
Sec61 alpha 2 subunit (S. cerevisiae)
chr12_-_49351148 0.04 ENST00000398092.4
ENST00000539611.1
RP11-302B13.5
ARF3
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr11_-_65625014 0.04 ENST00000534784.1
CFL1
cofilin 1 (non-muscle)
chr19_+_49838653 0.04 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr1_+_27114589 0.04 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr14_-_21492251 0.04 ENST00000554398.1
NDRG2
NDRG family member 2
chr16_-_55866997 0.04 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr11_-_65624415 0.03 ENST00000524553.1
ENST00000527344.1
CFL1
cofilin 1 (non-muscle)
chr1_+_109102652 0.03 ENST00000370035.3
ENST00000405454.1
FAM102B
family with sequence similarity 102, member B
chr17_+_41924536 0.03 ENST00000317310.4
CD300LG
CD300 molecule-like family member g
chr1_+_36621174 0.03 ENST00000429533.2
MAP7D1
MAP7 domain containing 1
chr12_-_49351303 0.03 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr17_+_36873677 0.03 ENST00000471200.1
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr19_+_39109735 0.03 ENST00000593149.1
ENST00000248342.4
ENST00000538434.1
ENST00000588934.1
ENST00000545173.2
ENST00000589307.1
ENST00000586513.1
ENST00000591409.1
ENST00000592558.1
EIF3K
eukaryotic translation initiation factor 3, subunit K
chr6_-_109777128 0.03 ENST00000358807.3
ENST00000358577.3
MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr17_+_75450146 0.02 ENST00000585929.1
ENST00000590917.1
SEPT9
septin 9
chr17_-_17726907 0.02 ENST00000423161.3
SREBF1
sterol regulatory element binding transcription factor 1
chrX_+_15525426 0.02 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr19_-_49314269 0.02 ENST00000545387.2
ENST00000316273.6
ENST00000402551.1
ENST00000598162.1
ENST00000599246.1
BCAT2
branched chain amino-acid transaminase 2, mitochondrial
chrX_+_51636629 0.02 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1
melanoma antigen family D, 1
chr17_-_19651654 0.02 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr19_-_49314169 0.02 ENST00000597011.1
ENST00000601681.1
BCAT2
branched chain amino-acid transaminase 2, mitochondrial
chr3_+_155838337 0.02 ENST00000490337.1
ENST00000389636.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr12_+_3600356 0.02 ENST00000382622.3
PRMT8
protein arginine methyltransferase 8
chr5_-_16936340 0.02 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr17_-_2117600 0.02 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr20_-_3154162 0.02 ENST00000360342.3
LZTS3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr9_+_132597722 0.02 ENST00000372429.3
ENST00000315480.4
ENST00000358355.1
USP20
ubiquitin specific peptidase 20
chr12_+_121647868 0.02 ENST00000359949.7
ENST00000541532.1
ENST00000543171.1
ENST00000538701.1
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr17_-_19651668 0.02 ENST00000494157.2
ENST00000225740.6
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr7_-_124405681 0.02 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr2_-_208030295 0.01 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr4_+_4861385 0.01 ENST00000382723.4
MSX1
msh homeobox 1
chr14_+_89290965 0.01 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
TTC8
tetratricopeptide repeat domain 8
chr12_-_124456598 0.01 ENST00000539761.1
ENST00000539551.1
CCDC92
coiled-coil domain containing 92
chr19_-_5624057 0.01 ENST00000590262.1
SAFB2
scaffold attachment factor B2
chr6_+_43140095 0.01 ENST00000457278.2
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr12_+_121647962 0.01 ENST00000542067.1
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
chr1_+_65730385 0.01 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr3_+_10289707 0.01 ENST00000287652.4
TATDN2
TatD DNase domain containing 2
chr1_+_27668505 0.01 ENST00000318074.5
SYTL1
synaptotagmin-like 1
chr3_-_47517302 0.01 ENST00000441517.2
ENST00000545718.1
SCAP
SREBF chaperone
chr17_-_73775839 0.01 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr1_+_36621529 0.01 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr12_-_52967600 0.00 ENST00000549343.1
ENST00000305620.2
KRT74
keratin 74
chr1_-_27216729 0.00 ENST00000431781.2
ENST00000374135.4
GPN2
GPN-loop GTPase 2
chr1_+_153963227 0.00 ENST00000368567.4
ENST00000392558.4
RPS27
ribosomal protein S27
chr19_-_6279932 0.00 ENST00000252674.7
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr3_+_37035263 0.00 ENST00000458205.2
ENST00000539477.1
MLH1
mutL homolog 1
chr3_-_114477962 0.00 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.0 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:2000769 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)