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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for VAX2_RHOXF2

Z-value: 0.45

Motif logo

Transcription factors associated with VAX2_RHOXF2

Gene Symbol Gene ID Gene Info
ENSG00000116035.2 VAX2
ENSG00000131721.4 RHOXF2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VAX2hg19_v2_chr2_+_71127699_711277440.582.2e-01Click!
RHOXF2hg19_v2_chrX_+_119292467_119292467-0.049.4e-01Click!

Activity profile of VAX2_RHOXF2 motif

Sorted Z-values of VAX2_RHOXF2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX2_RHOXF2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_162336686 0.48 ENST00000420220.1
C1orf226
chromosome 1 open reading frame 226
chr7_-_99716914 0.45 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr6_+_26402517 0.31 ENST00000414912.2
BTN3A1
butyrophilin, subfamily 3, member A1
chr1_+_62439037 0.28 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr19_-_52307357 0.24 ENST00000594900.1
FPR1
formyl peptide receptor 1
chr6_+_26402465 0.20 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr2_-_74619152 0.20 ENST00000440727.1
ENST00000409240.1
DCTN1
dynactin 1
chr2_-_74618964 0.18 ENST00000417090.1
ENST00000409868.1
DCTN1
dynactin 1
chr6_-_33663474 0.17 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr17_+_4692230 0.17 ENST00000331264.7
GLTPD2
glycolipid transfer protein domain containing 2
chr12_+_78359999 0.16 ENST00000550503.1
NAV3
neuron navigator 3
chr4_+_169418255 0.15 ENST00000505667.1
ENST00000511948.1
PALLD
palladin, cytoskeletal associated protein
chrX_+_10126488 0.15 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr4_+_66536248 0.15 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr6_+_26365443 0.15 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr1_+_225600404 0.13 ENST00000366845.2
AC092811.1
AC092811.1
chr14_+_56584414 0.13 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr16_+_69345243 0.13 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr19_-_3557570 0.12 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr7_-_99716952 0.12 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr7_-_99716940 0.12 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr17_-_40337470 0.12 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr5_-_136649218 0.12 ENST00000510405.1
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr3_-_112127981 0.12 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr1_-_57045228 0.12 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr4_+_169418195 0.11 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr17_+_43238438 0.11 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr4_+_159727272 0.11 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr3_-_191000172 0.11 ENST00000427544.2
UTS2B
urotensin 2B
chr1_-_159832438 0.10 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr7_-_99717463 0.10 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr19_+_11071546 0.10 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr3_+_157154578 0.10 ENST00000295927.3
PTX3
pentraxin 3, long
chr7_+_148936732 0.10 ENST00000335870.2
ZNF212
zinc finger protein 212
chr6_+_26365387 0.10 ENST00000532865.1
ENST00000530653.1
ENST00000527417.1
BTN3A2
butyrophilin, subfamily 3, member A2
chr19_-_46088068 0.10 ENST00000263275.4
ENST00000323060.3
OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr15_+_58702742 0.09 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr7_-_100860851 0.09 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr20_+_43990576 0.09 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr1_+_160370344 0.09 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr10_+_18549645 0.08 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr1_+_35258592 0.08 ENST00000342280.4
ENST00000450137.1
GJA4
gap junction protein, alpha 4, 37kDa
chr7_+_100860949 0.08 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr14_+_32798547 0.08 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chrX_+_135730297 0.08 ENST00000370629.2
CD40LG
CD40 ligand
chr10_+_99205894 0.08 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
ZDHHC16
zinc finger, DHHC-type containing 16
chrX_+_135730373 0.07 ENST00000370628.2
CD40LG
CD40 ligand
chr10_+_6779326 0.07 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr17_+_40610862 0.07 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr1_-_201140673 0.07 ENST00000367333.2
TMEM9
transmembrane protein 9
chr11_+_71900703 0.06 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr6_+_3259148 0.06 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr11_+_33061543 0.06 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1
t-complex 11, testis-specific-like 1
chr20_-_33735070 0.06 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr9_-_5339873 0.06 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr14_-_20923195 0.06 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr15_+_89922345 0.06 ENST00000558982.1
LINC00925
long intergenic non-protein coding RNA 925
chr12_-_118797475 0.05 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3
TAO kinase 3
chr1_+_54569968 0.05 ENST00000391366.1
AL161915.1
Uncharacterized protein
chr10_+_99205959 0.05 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
ZDHHC16
zinc finger, DHHC-type containing 16
chr12_+_26348246 0.05 ENST00000422622.2
SSPN
sarcospan
chr8_-_1922789 0.05 ENST00000521498.1
RP11-439C15.4
RP11-439C15.4
chr10_-_92681033 0.05 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr4_+_88571429 0.05 ENST00000339673.6
ENST00000282479.7
DMP1
dentin matrix acidic phosphoprotein 1
chr4_-_186696425 0.04 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr1_-_149900122 0.04 ENST00000271628.8
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr12_-_118796910 0.04 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr12_+_131438443 0.04 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr12_+_26348429 0.04 ENST00000242729.2
SSPN
sarcospan
chr7_-_44122063 0.04 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM
polymerase (DNA directed), mu
chr4_-_186696515 0.04 ENST00000456596.1
ENST00000414724.1
SORBS2
sorbin and SH3 domain containing 2
chr7_+_99717230 0.04 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr4_-_186696561 0.04 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr6_+_34204642 0.04 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr2_+_169926047 0.04 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9
dehydrogenase/reductase (SDR family) member 9
chrX_+_7137475 0.03 ENST00000217961.4
STS
steroid sulfatase (microsomal), isozyme S
chr12_-_9760482 0.03 ENST00000229402.3
KLRB1
killer cell lectin-like receptor subfamily B, member 1
chr16_-_55866997 0.03 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr6_+_130339710 0.03 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr1_+_153747746 0.03 ENST00000368661.3
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr8_-_91095099 0.03 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chrX_+_36254051 0.03 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr9_-_95166841 0.03 ENST00000262551.4
OGN
osteoglycin
chr9_+_125132803 0.03 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr17_-_41466555 0.03 ENST00000586231.1
LINC00910
long intergenic non-protein coding RNA 910
chr6_+_167536230 0.03 ENST00000341935.5
ENST00000349984.4
CCR6
chemokine (C-C motif) receptor 6
chr11_+_71900572 0.03 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr7_+_6655225 0.03 ENST00000457543.3
ZNF853
zinc finger protein 853
chr4_-_69111401 0.03 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr5_+_129083772 0.03 ENST00000564719.1
KIAA1024L
KIAA1024-like
chr11_-_107729887 0.03 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr1_-_24151903 0.03 ENST00000436439.2
ENST00000374490.3
HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr18_-_67623906 0.02 ENST00000583955.1
CD226
CD226 molecule
chr7_+_73245193 0.02 ENST00000340958.2
CLDN4
claudin 4
chr5_+_66300446 0.02 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chrX_+_43515467 0.02 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr20_-_50722183 0.02 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr14_+_101359265 0.02 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr5_+_140557371 0.02 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr7_+_115862858 0.02 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr2_-_85555385 0.02 ENST00000377386.3
TGOLN2
trans-golgi network protein 2
chr9_-_95166884 0.02 ENST00000375561.5
OGN
osteoglycin
chr11_-_62521614 0.02 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr15_-_37393406 0.02 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr6_-_138866823 0.02 ENST00000342260.5
NHSL1
NHS-like 1
chrX_-_77225135 0.02 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr4_-_77328458 0.02 ENST00000388914.3
ENST00000434846.2
CCDC158
coiled-coil domain containing 158
chr2_-_74618907 0.02 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr4_-_74486347 0.02 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr19_+_36632485 0.02 ENST00000586963.1
CAPNS1
calpain, small subunit 1
chr19_+_36632204 0.01 ENST00000592354.1
CAPNS1
calpain, small subunit 1
chr2_-_214016314 0.01 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr18_-_67624412 0.01 ENST00000580335.1
CD226
CD226 molecule
chr2_+_228736321 0.01 ENST00000309931.2
DAW1
dynein assembly factor with WDR repeat domains 1
chr15_+_58430567 0.01 ENST00000536493.1
AQP9
aquaporin 9
chr6_+_53883708 0.01 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP
muscular LMNA-interacting protein
chr4_+_88896819 0.01 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr16_-_28608424 0.01 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr14_+_74034310 0.01 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr18_-_67624160 0.01 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr14_+_103851712 0.01 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr4_+_151503077 0.01 ENST00000317605.4
MAB21L2
mab-21-like 2 (C. elegans)
chr20_+_15177480 0.01 ENST00000402914.1
MACROD2
MACRO domain containing 2
chr10_-_99205607 0.01 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1
exosome component 1
chr14_+_20923350 0.01 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr9_+_12693336 0.01 ENST00000381137.2
ENST00000388918.5
TYRP1
tyrosinase-related protein 1
chr17_+_66511540 0.01 ENST00000588188.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr15_-_49912944 0.01 ENST00000559905.1
FAM227B
family with sequence similarity 227, member B
chr5_-_115890554 0.01 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr19_+_12175504 0.01 ENST00000439326.3
ZNF844
zinc finger protein 844
chr14_+_32798462 0.00 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr6_+_26440700 0.00 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr9_+_125133467 0.00 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr13_-_36050819 0.00 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr16_+_72088376 0.00 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr1_+_75600567 0.00 ENST00000356261.3
LHX8
LIM homeobox 8
chr15_+_49462397 0.00 ENST00000396509.2
GALK2
galactokinase 2
chr2_-_198540751 0.00 ENST00000429081.1
RFTN2
raftlin family member 2
chr5_-_149829244 0.00 ENST00000312037.5
RPS14
ribosomal protein S14
chr17_-_71258491 0.00 ENST00000397671.1
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr2_+_200472779 0.00 ENST00000427045.1
ENST00000419243.1
AC093590.1
AC093590.1
chr17_-_18430160 0.00 ENST00000392176.3
FAM106A
family with sequence similarity 106, member A
chr15_+_58430368 0.00 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr3_+_186353756 0.00 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr11_-_117747434 0.00 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.1 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.8 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0044793 negative regulation by host of viral process(GO:0044793)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0060187 cell pole(GO:0060187)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening