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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HMX1

Z-value: 1.30

Motif logo

Transcription factors associated with HMX1

Gene Symbol Gene ID Gene Info
ENSG00000215612.5 H6 family homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMX1hg19_v2_chr4_-_8873531_88735430.805.8e-02Click!

Activity profile of HMX1 motif

Sorted Z-values of HMX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_99531709 1.00 ENST00000266066.3
secreted frizzled-related protein 5
chr16_+_83986827 0.80 ENST00000393306.1
ENST00000565123.1
oxidative stress induced growth inhibitor 1
chr17_-_78450398 0.76 ENST00000306773.4
neuronal pentraxin I
chr16_-_776431 0.67 ENST00000293889.6
coiled-coil domain containing 78
chr16_-_88752889 0.65 ENST00000332281.5
snail family zinc finger 3
chr10_+_99258625 0.60 ENST00000370664.3
ubiquitin domain containing 1
chr11_+_826136 0.57 ENST00000528315.1
ENST00000533803.1
EF-hand calcium binding domain 4A
chr2_-_130939115 0.54 ENST00000441135.1
ENST00000339679.7
ENST00000426662.2
ENST00000443958.2
ENST00000351288.6
ENST00000453750.1
ENST00000452225.2
sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
chr22_-_18923655 0.52 ENST00000438924.1
ENST00000457083.1
ENST00000420436.1
ENST00000334029.2
ENST00000357068.6
proline dehydrogenase (oxidase) 1
chr2_+_130939235 0.51 ENST00000425361.1
ENST00000457492.1
mitotic spindle organizing protein 2B
chr14_+_56584414 0.51 ENST00000559044.1
pellino E3 ubiquitin protein ligase family member 2
chr17_+_7284365 0.48 ENST00000311668.2
tyrosine kinase, non-receptor, 1
chr11_+_118478313 0.48 ENST00000356063.5
pleckstrin homology-like domain, family B, member 1
chr9_-_130487143 0.48 ENST00000419060.1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr19_+_41305330 0.47 ENST00000593972.1
egl-9 family hypoxia-inducible factor 2
chr22_-_38480100 0.46 ENST00000427592.1
solute carrier family 16 (monocarboxylate transporter), member 8
chr2_-_220436248 0.46 ENST00000265318.4
obscurin-like 1
chr17_-_1619535 0.45 ENST00000573075.1
ENST00000574306.1
MIR22 host gene (non-protein coding)
chr3_-_138553779 0.45 ENST00000461451.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr7_-_752577 0.45 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
protein kinase, cAMP-dependent, regulatory, type I, beta
chr22_-_39268308 0.45 ENST00000407418.3
chromobox homolog 6
chr8_+_145438870 0.44 ENST00000527931.1
family with sequence similarity 203, member B
chr17_+_38465441 0.44 ENST00000577646.1
ENST00000254066.5
retinoic acid receptor, alpha
chr9_+_116263639 0.43 ENST00000343817.5
regulator of G-protein signaling 3
chr19_-_36545128 0.43 ENST00000538849.1
THAP domain containing 8
chr22_-_39268192 0.43 ENST00000216083.6
chromobox homolog 6
chr9_+_116263778 0.42 ENST00000394646.3
regulator of G-protein signaling 3
chr22_+_50781723 0.42 ENST00000359139.3
ENST00000395741.3
ENST00000395744.3
protein phosphatase 6, regulatory subunit 2
chr16_+_28996416 0.42 ENST00000395456.2
ENST00000454369.2
linker for activation of T cells
chr2_-_220435963 0.41 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
obscurin-like 1
chr17_-_1619568 0.40 ENST00000571595.1
MIR22 host gene (non-protein coding)
chr12_+_57482877 0.40 ENST00000342556.6
ENST00000357680.4
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr22_-_41677625 0.39 ENST00000452543.1
ENST00000418067.1
Ran GTPase activating protein 1
chr3_+_47021168 0.39 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
neurobeachin-like 2
chr21_+_46875424 0.39 ENST00000359759.4
collagen, type XVIII, alpha 1
chr3_+_57994127 0.38 ENST00000490882.1
ENST00000295956.4
ENST00000358537.3
ENST00000429972.2
ENST00000348383.5
ENST00000357272.4
filamin B, beta
chr1_-_233431458 0.38 ENST00000258229.9
ENST00000430153.1
pecanex-like 2 (Drosophila)
chr16_-_70712229 0.38 ENST00000562883.2
metastasis suppressor 1-like
chr4_-_2420357 0.37 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
zinc finger, FYVE domain containing 28
chr11_-_116968987 0.37 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK family kinase 3
chr7_-_105332084 0.37 ENST00000472195.1
ataxin 7-like 1
chr8_+_98881268 0.36 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
matrilin 2
chr19_+_41305612 0.36 ENST00000594380.1
ENST00000593397.1
ENST00000601733.1
egl-9 family hypoxia-inducible factor 2
chr17_+_42836329 0.36 ENST00000200557.6
ADAM metallopeptidase domain 11
chr17_-_1619491 0.36 ENST00000570416.1
ENST00000575626.1
ENST00000610106.1
ENST00000608198.1
ENST00000609442.1
ENST00000334146.3
ENST00000576489.1
ENST00000608245.1
ENST00000609398.1
ENST00000608913.1
ENST00000574016.1
ENST00000571091.1
ENST00000573127.1
ENST00000609990.1
ENST00000576749.1
MIR22 host gene (non-protein coding)
chr16_+_28996364 0.36 ENST00000564277.1
linker for activation of T cells
chr1_-_198906528 0.35 ENST00000432296.1
MIR181A1 host gene (non-protein coding)
chr9_+_140083099 0.35 ENST00000322310.5
Sjogren syndrome nuclear autoantigen 1
chr17_-_79212884 0.35 ENST00000300714.3
ENTH domain containing 2
chr17_+_74381343 0.35 ENST00000392496.3
sphingosine kinase 1
chrX_-_153285395 0.34 ENST00000369980.3
interleukin-1 receptor-associated kinase 1
chr9_-_130616915 0.34 ENST00000344849.3
endoglin
chr1_-_207095324 0.34 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
Fas apoptotic inhibitory molecule 3
chr19_-_10697895 0.34 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
adaptor-related protein complex 1, mu 2 subunit
chr5_+_141016969 0.34 ENST00000518856.1
RELT-like 2
chr1_+_6052700 0.34 ENST00000378092.1
ENST00000445501.1
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr21_+_46875395 0.34 ENST00000355480.5
collagen, type XVIII, alpha 1
chr19_+_6464243 0.33 ENST00000600229.1
ENST00000356762.3
crumbs homolog 3 (Drosophila)
chr3_-_52864680 0.33 ENST00000406595.1
ENST00000485816.1
ENST00000434759.3
ENST00000346281.5
ENST00000266041.4
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr19_+_55987998 0.33 ENST00000591164.1
zinc finger protein 628
chr11_-_65308082 0.33 ENST00000532661.1
latent transforming growth factor beta binding protein 3
chrX_-_153744434 0.33 ENST00000369643.1
ENST00000393572.1
family with sequence similarity 3, member A
chrX_-_153285251 0.33 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
interleukin-1 receptor-associated kinase 1
chr12_+_57482665 0.33 ENST00000300131.3
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr17_+_79679369 0.33 ENST00000350690.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chrX_-_153744507 0.32 ENST00000442929.1
ENST00000426266.1
ENST00000359889.5
ENST00000369641.3
ENST00000447601.2
ENST00000434658.2
family with sequence similarity 3, member A
chr11_+_59522900 0.32 ENST00000529177.1
syntaxin 3
chr5_+_141016508 0.32 ENST00000444782.1
ENST00000521367.1
ENST00000297164.3
RELT-like 2
chr11_+_69455855 0.32 ENST00000227507.2
ENST00000536559.1
cyclin D1
chr16_+_30212378 0.32 ENST00000569485.1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr19_-_13068012 0.32 ENST00000316939.1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr5_-_172662303 0.32 ENST00000517440.1
ENST00000329198.4
NK2 homeobox 5
chr2_-_197457335 0.31 ENST00000260983.3
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr11_+_59522837 0.31 ENST00000437946.2
syntaxin 3
chrX_-_153599578 0.31 ENST00000360319.4
ENST00000344736.4
filamin A, alpha
chr1_+_110162448 0.31 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
adenosine monophosphate deaminase 2
chr9_-_140082983 0.31 ENST00000323927.2
anaphase promoting complex subunit 2
chr17_-_73874654 0.30 ENST00000254816.2
tripartite motif containing 47
chr12_-_7077125 0.30 ENST00000545555.2
prohibitin 2
chr16_+_28996572 0.30 ENST00000360872.5
ENST00000566177.1
ENST00000354453.4
linker for activation of T cells
chr9_-_130617029 0.30 ENST00000373203.4
endoglin
chr1_-_17338386 0.30 ENST00000341676.5
ENST00000452699.1
ATPase type 13A2
chr17_-_6947225 0.30 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
solute carrier family 16, member 11
chr19_+_41305627 0.30 ENST00000593525.1
egl-9 family hypoxia-inducible factor 2
chr3_+_49711777 0.29 ENST00000442186.1
ENST00000438011.1
ENST00000457042.1
acylaminoacyl-peptide hydrolase
chr2_-_46769694 0.29 ENST00000522587.1
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chr20_+_57464200 0.29 ENST00000604005.1
GNAS complex locus
chr17_+_79679299 0.29 ENST00000331531.5
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr1_-_41328018 0.28 ENST00000372638.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr19_-_40791211 0.28 ENST00000579047.1
v-akt murine thymoma viral oncogene homolog 2
chr16_+_67226019 0.28 ENST00000379378.3
E2F transcription factor 4, p107/p130-binding
chr19_-_18385221 0.28 ENST00000595654.2
ENST00000593659.1
ENST00000599528.1
KIAA1683
chr16_-_70713928 0.27 ENST00000576338.1
metastasis suppressor 1-like
chr19_+_41305740 0.26 ENST00000596517.1
egl-9 family hypoxia-inducible factor 2
chr9_+_131644398 0.26 ENST00000372599.3
leucine rich repeat containing 8 family, member A
chr17_-_42298331 0.26 ENST00000343638.5
upstream binding transcription factor, RNA polymerase I
chr9_+_131644388 0.26 ENST00000372600.4
leucine rich repeat containing 8 family, member A
chr22_-_32022280 0.26 ENST00000442379.1
phosphatidylserine decarboxylase
chr11_-_17035943 0.26 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
pleckstrin homology domain containing, family A member 7
chr19_+_41305406 0.25 ENST00000406058.2
ENST00000593726.1
egl-9 family hypoxia-inducible factor 2
chrX_+_53123314 0.25 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
long intergenic non-protein coding RNA 1155
chr3_-_49066811 0.25 ENST00000442157.1
ENST00000326739.4
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr2_-_69870835 0.25 ENST00000409085.4
ENST00000406297.3
AP2 associated kinase 1
chr19_+_41313017 0.25 ENST00000595621.1
ENST00000595051.1
egl-9 family hypoxia-inducible factor 2
chr5_-_172662230 0.25 ENST00000424406.2
NK2 homeobox 5
chr6_-_42418999 0.25 ENST00000340840.2
ENST00000354325.2
transcriptional regulating factor 1
chr19_-_52227221 0.25 ENST00000222115.1
ENST00000540069.2
hyaluronan synthase 1
chr1_+_9648921 0.24 ENST00000377376.4
ENST00000340305.5
ENST00000340381.6
transmembrane protein 201
chr20_-_62601218 0.24 ENST00000369888.1
zinc finger protein 512B
chr9_-_130331297 0.24 ENST00000373312.3
family with sequence similarity 129, member B
chr12_-_112819896 0.24 ENST00000377560.5
ENST00000430131.2
ENST00000550722.1
ENST00000550724.1
HECT domain containing E3 ubiquitin protein ligase 4
chr3_+_50316458 0.24 ENST00000316436.3
leucine-rich single-pass membrane protein 2
chr16_+_88872176 0.24 ENST00000569140.1
chromatin licensing and DNA replication factor 1
chr17_-_79876010 0.24 ENST00000328666.6
sirtuin 7
chr11_+_60699222 0.23 ENST00000536409.1
transmembrane protein 132A
chr19_-_4124079 0.23 ENST00000394867.4
ENST00000262948.5
mitogen-activated protein kinase kinase 2
chr19_+_41305085 0.23 ENST00000303961.4
egl-9 family hypoxia-inducible factor 2
chr19_+_1407733 0.23 ENST00000592453.1
DAZ associated protein 1
chr6_-_2245892 0.23 ENST00000380815.4
GDP-mannose 4,6-dehydratase
chr3_+_127391769 0.23 ENST00000393363.3
ENST00000232744.8
ENST00000453791.2
ankyrin repeat and BTB (POZ) domain containing 1
chr5_-_180230830 0.22 ENST00000427865.2
ENST00000514283.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr1_-_6052463 0.22 ENST00000378156.4
nephronophthisis 4
chr9_+_131644781 0.22 ENST00000259324.5
leucine rich repeat containing 8 family, member A
chr15_-_90198659 0.22 ENST00000394412.3
kinesin family member 7
chr5_+_139027877 0.22 ENST00000302517.3
CXXC finger protein 5
chr7_+_872107 0.22 ENST00000405266.1
ENST00000401592.1
ENST00000403868.1
ENST00000425407.2
Sad1 and UNC84 domain containing 1
chr7_+_155250824 0.22 ENST00000297375.4
engrailed homeobox 2
chr6_+_33359582 0.22 ENST00000450504.1
kinesin family member C1
chr22_+_38349724 0.22 ENST00000470701.1
polymerase (RNA) II (DNA directed) polypeptide F
chr19_-_1401486 0.22 ENST00000252288.2
ENST00000447102.3
guanidinoacetate N-methyltransferase
chr22_-_39096981 0.22 ENST00000427389.1
Josephin domain containing 1
chr12_+_110152033 0.22 ENST00000538780.1
family with sequence similarity 222, member A
chr20_+_49348109 0.21 ENST00000396039.1
par-6 family cell polarity regulator beta
chr1_-_17338267 0.21 ENST00000326735.8
ATPase type 13A2
chr17_+_79213039 0.21 ENST00000431388.2
chromosome 17 open reading frame 89
chr17_+_42836521 0.21 ENST00000535346.1
ADAM metallopeptidase domain 11
chr2_-_27712583 0.21 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
intraflagellar transport 172 homolog (Chlamydomonas)
chr1_+_160336851 0.21 ENST00000302101.5
nescient helix loop helix 1
chr3_+_151986709 0.21 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
muscleblind-like splicing regulator 1
chr14_+_23775971 0.21 ENST00000250405.5
BCL2-like 2
chr17_+_77751931 0.21 ENST00000310942.4
ENST00000269399.5
chromobox homolog 2
chr19_-_42721819 0.20 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
death effector domain containing 2
chr7_-_156803329 0.20 ENST00000252971.6
motor neuron and pancreas homeobox 1
chr19_+_55587266 0.20 ENST00000201647.6
ENST00000540810.1
EPS8-like 1
chr16_+_11038345 0.20 ENST00000409790.1
C-type lectin domain family 16, member A
chr3_-_52312636 0.20 ENST00000296490.3
WD repeat domain 82
chr1_+_178994939 0.20 ENST00000440702.1
family with sequence similarity 20, member B
chr18_+_11981547 0.20 ENST00000588927.1
inositol(myo)-1(or 4)-monophosphatase 2
chr16_+_29984962 0.20 ENST00000308893.4
TAO kinase 2
chr14_+_105781048 0.20 ENST00000458164.2
ENST00000447393.1
phosphofurin acidic cluster sorting protein 2
chr16_+_85646763 0.20 ENST00000411612.1
ENST00000253458.7
Gse1 coiled-coil protein
chr17_-_42298201 0.20 ENST00000527034.1
upstream binding transcription factor, RNA polymerase I
chr16_-_67190152 0.20 ENST00000486556.1
TNFRSF1A-associated via death domain
chr19_-_46285736 0.19 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
dystrophia myotonica-protein kinase
chr14_-_103523745 0.19 ENST00000361246.2
CDC42 binding protein kinase beta (DMPK-like)
chr22_+_47158518 0.19 ENST00000337137.4
ENST00000380995.1
ENST00000407381.3
TBC1 domain family, member 22A
chr2_-_27545921 0.19 ENST00000402310.1
ENST00000405983.1
ENST00000403262.2
ENST00000428910.1
ENST00000402722.1
ENST00000399052.4
ENST00000380044.1
ENST00000405076.1
MpV17 mitochondrial inner membrane protein
chr11_-_62607036 0.19 ENST00000311713.7
ENST00000278856.4
WD repeat domain 74
chr16_+_3062457 0.19 ENST00000445369.2
claudin 9
chr1_-_201476274 0.19 ENST00000340006.2
cysteine and glycine-rich protein 1
chr1_-_154946792 0.19 ENST00000412170.1
SHC (Src homology 2 domain containing) transforming protein 1
chr1_-_32229523 0.19 ENST00000398547.1
ENST00000373655.2
ENST00000373658.3
ENST00000257070.4
brain-specific angiogenesis inhibitor 2
chr1_+_202431859 0.19 ENST00000391959.3
ENST00000367270.4
protein phosphatase 1, regulatory subunit 12B
chr17_+_40440481 0.19 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
signal transducer and activator of transcription 5A
chr11_+_66624527 0.19 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr16_+_85645007 0.19 ENST00000405402.2
Gse1 coiled-coil protein
chr6_+_4773205 0.19 ENST00000440139.1
chromodomain protein, Y-like
chr17_+_40440094 0.19 ENST00000546010.2
signal transducer and activator of transcription 5A
chr5_-_172662197 0.19 ENST00000521848.1
NK2 homeobox 5
chr11_-_67275542 0.18 ENST00000531506.1
cyclin-dependent kinase 2 associated protein 2
chr22_-_39096661 0.18 ENST00000216039.5
Josephin domain containing 1
chr11_+_65837907 0.18 ENST00000320580.4
phosphofurin acidic cluster sorting protein 1
chr1_-_28241024 0.18 ENST00000313433.7
ENST00000444045.1
replication protein A2, 32kDa
chr20_+_3451650 0.18 ENST00000262919.5
attractin
chr19_-_10687907 0.18 ENST00000589348.1
adaptor-related protein complex 1, mu 2 subunit
chr19_+_1407517 0.18 ENST00000336761.6
ENST00000233078.4
DAZ associated protein 1
chr6_+_2245982 0.17 ENST00000530346.1
ENST00000524770.1
ENST00000532124.1
ENST00000531092.1
ENST00000456943.2
ENST00000529893.1
GMDS antisense RNA 1 (head to head)
chr15_+_40763150 0.17 ENST00000306243.5
ENST00000559991.1
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr12_+_7060432 0.17 ENST00000318974.9
ENST00000456013.1
protein tyrosine phosphatase, non-receptor type 6
chr9_-_126692386 0.17 ENST00000373624.2
ENST00000394219.3
ENST00000373620.3
ENST00000394215.2
ENST00000373618.1
DENN/MADD domain containing 1A
chr1_-_201476220 0.17 ENST00000526723.1
ENST00000524951.1
cysteine and glycine-rich protein 1
chr9_-_100000957 0.17 ENST00000366109.2
ENST00000607322.1
RP11-498P14.5
chr16_-_1823114 0.17 ENST00000177742.3
ENST00000397375.2
mitochondrial ribosomal protein S34
chr5_-_1345199 0.17 ENST00000320895.5
CLPTM1-like
chr21_-_36259445 0.16 ENST00000399240.1
runt-related transcription factor 1
chr19_-_10687983 0.16 ENST00000587069.1
adaptor-related protein complex 1, mu 2 subunit
chr2_-_175462934 0.16 ENST00000392546.2
ENST00000436221.1
WAS/WASL interacting protein family, member 1
chr2_+_30454390 0.16 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
limb bud and heart development
chr11_+_1411503 0.16 ENST00000526678.1
BR serine/threonine kinase 2
chr12_-_49259643 0.16 ENST00000309739.5
Rho family GTPase 1
chr9_-_131940526 0.16 ENST00000372491.2
immediate early response 5-like
chr17_-_41132010 0.16 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1 readthrough
chr11_+_65819802 0.16 ENST00000528302.1
ENST00000322535.6
ENST00000524627.1
ENST00000533595.1
ENST00000530322.1
splicing factor 3b, subunit 2, 145kDa
chr10_-_135122603 0.15 ENST00000368563.2
tubulin, gamma complex associated protein 2
chr1_-_31196427 0.15 ENST00000373765.4
matrilin 1, cartilage matrix protein
chr14_-_21905424 0.15 ENST00000553622.1
chromodomain helicase DNA binding protein 8
chr18_+_13217965 0.15 ENST00000587905.1
low density lipoprotein receptor class A domain containing 4
chr17_+_41132564 0.15 ENST00000361677.1
ENST00000589705.1
RUN domain containing 1
chr14_+_23776024 0.15 ENST00000553781.1
ENST00000556100.1
ENST00000557236.1
ENST00000557579.1
BCL2L2-PABPN1 readthrough
BCL2-like 2
chr10_-_99258135 0.15 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19 nucleotide excision repair homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0003168 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.2 0.7 GO:0019732 antifungal humoral response(GO:0019732)
0.2 0.6 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.6 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.2 0.5 GO:1904351 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.2 2.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 1.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.7 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.3 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.4 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.5 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.4 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.5 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.1 GO:0051885 positive regulation of anagen(GO:0051885)
0.1 0.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.7 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.6 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.4 GO:0000255 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.1 0.8 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.2 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.1 0.3 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.3 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826)
0.0 0.2 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.4 GO:0070141 response to UV-A(GO:0070141)
0.0 0.3 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.3 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.3 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.5 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.5 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.5 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0061525 hindgut development(GO:0061525)
0.0 0.1 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.2 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.2 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0 0.1 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.2 GO:0003190 atrioventricular valve formation(GO:0003190)
0.0 0.7 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.1 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.2 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.0 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0072563 endothelial microparticle(GO:0072563)
0.2 0.6 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.4 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.7 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.9 GO:1990393 3M complex(GO:1990393)
0.1 0.5 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.1 0.7 GO:0098536 deuterosome(GO:0098536)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.1 0.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.3 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.5 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.3 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.3 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.2 0.6 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.2 0.8 GO:0010736 serum response element binding(GO:0010736)
0.1 0.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.5 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.7 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.6 GO:0005534 galactose binding(GO:0005534)
0.1 0.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.3 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0031852 opioid receptor binding(GO:0031628) mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.3 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.0 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 2.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 1.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1