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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HES1

Z-value: 0.88

Motif logo

Transcription factors associated with HES1

Gene Symbol Gene ID Gene Info
ENSG00000114315.3 hes family bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HES1hg19_v2_chr3_+_193853927_193853944-0.582.2e-01Click!

Activity profile of HES1 motif

Sorted Z-values of HES1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_94577074 1.10 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
interferon, alpha-inducible protein 27
chr11_-_615570 0.81 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr14_+_103394963 0.48 ENST00000559525.1
ENST00000559789.1
amnion associated transmembrane protein
chr2_+_86116396 0.43 ENST00000455121.3
AC105053.4
chr8_+_38614754 0.39 ENST00000521642.1
transforming, acidic coiled-coil containing protein 1
chr14_+_67708344 0.33 ENST00000557237.1
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr10_+_104474353 0.33 ENST00000602647.1
ENST00000602439.1
ENST00000602764.1
sideroflexin 2
chr15_+_89182156 0.30 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr10_-_95360983 0.29 ENST00000371464.3
retinol binding protein 4, plasma
chr3_+_121554046 0.29 ENST00000273668.2
ENST00000451944.2
ELL associated factor 2
chr15_+_89182178 0.28 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr2_+_187350973 0.28 ENST00000544130.1
zinc finger CCCH-type containing 15
chr8_+_22298767 0.27 ENST00000522000.1
protein phosphatase 3, catalytic subunit, gamma isozyme
chrX_+_21958814 0.27 ENST00000379404.1
ENST00000415881.2
spermine synthase
chr2_-_100106419 0.26 ENST00000393445.3
ENST00000258428.3
REV1, polymerase (DNA directed)
chr8_-_99955042 0.25 ENST00000519420.1
serine/threonine kinase 3
chr22_+_24819565 0.25 ENST00000424232.1
ENST00000486108.1
adenosine A2a receptor
chr19_-_7936344 0.23 ENST00000599142.1
Protein FLJ22184
chr2_+_232575168 0.23 ENST00000440384.1
prothymosin, alpha
chr20_-_3154162 0.23 ENST00000360342.3
Homo sapiens leucine zipper, putative tumor suppressor family member 3 (LZTS3), mRNA.
chr1_+_53793885 0.22 ENST00000445039.2
RP4-784A16.5
chr7_-_155089251 0.22 ENST00000609974.1
AC144652.1
chr19_-_3869012 0.21 ENST00000592398.1
ENST00000262961.4
ENST00000439086.2
zinc finger RNA binding protein 2
chr19_+_843314 0.21 ENST00000544537.2
proteinase 3
chr16_+_318638 0.20 ENST00000412541.1
ENST00000435035.1
Rho GDP dissociation inhibitor (GDI) gamma
chr17_-_48207115 0.20 ENST00000511964.1
sterile alpha motif domain containing 14
chr22_+_24115000 0.20 ENST00000215743.3
matrix metallopeptidase 11 (stromelysin 3)
chr2_+_46926326 0.19 ENST00000394861.2
suppressor of cytokine signaling 5
chr8_-_142318398 0.19 ENST00000520137.1
solute carrier family 45, member 4
chr22_+_29168652 0.19 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
coiled-coil domain containing 117
chr12_-_25783684 0.19 ENST00000538178.1
intermediate filament tail domain containing 1
chr16_+_2039946 0.19 ENST00000248121.2
ENST00000568896.1
synaptogyrin 3
chr9_-_107754034 0.19 ENST00000457720.1
RP11-217B7.3
chr17_-_80291818 0.19 ENST00000269389.3
ENST00000581691.1
secreted and transmembrane 1
chr9_+_133320301 0.19 ENST00000352480.5
argininosuccinate synthase 1
chr15_+_89181974 0.18 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr21_-_40685536 0.18 ENST00000341322.4
bromodomain and WD repeat domain containing 1
chr12_+_7022909 0.18 ENST00000537688.1
enolase 2 (gamma, neuronal)
chr1_-_118472171 0.18 ENST00000369442.3
ganglioside induced differentiation associated protein 2
chr4_+_57774042 0.18 ENST00000309042.7
RE1-silencing transcription factor
chr4_-_10458982 0.18 ENST00000326756.3
zinc finger protein 518B
chr22_-_42310570 0.18 ENST00000457093.1
shisa family member 8
chr22_+_29279552 0.17 ENST00000544604.2
zinc and ring finger 3
chr2_-_224702257 0.17 ENST00000409375.1
adaptor-related protein complex 1, sigma 3 subunit
chr12_-_117537240 0.17 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
tescalcin
chr6_+_86159821 0.17 ENST00000369651.3
5'-nucleotidase, ecto (CD73)
chr17_+_5973740 0.17 ENST00000576083.1
WSC domain containing 1
chr1_+_6845384 0.17 ENST00000303635.7
calmodulin binding transcription activator 1
chr11_+_64004888 0.17 ENST00000541681.1
vascular endothelial growth factor B
chr1_-_9189144 0.17 ENST00000414642.2
G protein-coupled receptor 157
chr20_-_20693131 0.17 ENST00000202677.7
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr4_+_76439649 0.17 ENST00000507557.1
THAP domain containing 6
chr11_-_72852320 0.16 ENST00000422375.1
FCH and double SH3 domains 2
chr3_+_23851928 0.16 ENST00000467766.1
ENST00000424381.1
ubiquitin-conjugating enzyme E2E 1
chr2_+_208576259 0.16 ENST00000392209.3
cyclin Y-like 1
chr19_+_8274185 0.16 ENST00000558268.1
ENST00000558331.1
ceramide synthase 4
chr21_-_18985230 0.16 ENST00000457956.1
ENST00000348354.6
BTG family, member 3
chr17_-_19880992 0.16 ENST00000395536.3
ENST00000576896.1
ENST00000225737.6
A kinase (PRKA) anchor protein 10
chr8_+_22298578 0.16 ENST00000240139.5
ENST00000289963.8
ENST00000397775.3
protein phosphatase 3, catalytic subunit, gamma isozyme
chr11_-_111383064 0.16 ENST00000525791.1
ENST00000456861.2
ENST00000356018.2
B-cell translocation gene 4
chr12_+_49761147 0.15 ENST00000549298.1
spermatogenesis associated, serine-rich 2
chr4_-_185655212 0.15 ENST00000541971.1
centromere protein U
chr2_-_200715834 0.15 ENST00000420128.1
ENST00000416668.1
formiminotransferase cyclodeaminase N-terminal like
chr2_-_96811170 0.15 ENST00000288943.4
dual specificity phosphatase 2
chr14_+_93260642 0.15 ENST00000355976.2
golgin A5
chr1_+_220267429 0.14 ENST00000366922.1
ENST00000302637.5
isoleucyl-tRNA synthetase 2, mitochondrial
chr1_-_101491319 0.14 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
diphthamide biosynthesis 5
chr14_+_102027688 0.14 ENST00000510508.4
ENST00000359323.3
deiodinase, iodothyronine, type III
chr2_+_187350883 0.14 ENST00000337859.6
zinc finger CCCH-type containing 15
chr12_+_107349606 0.14 ENST00000547242.1
ENST00000551489.1
ENST00000550344.1
chromosome 12 open reading frame 23
chr1_-_45805607 0.14 ENST00000372104.1
ENST00000448481.1
ENST00000483127.1
ENST00000528013.2
ENST00000456914.2
mutY homolog
chr14_+_56046990 0.14 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
kinectin 1 (kinesin receptor)
chr18_+_74207477 0.14 ENST00000532511.1
uncharacterized protein LOC400658
chrX_-_153095813 0.13 ENST00000544474.1
PDZ domain containing 4
chr17_+_28256874 0.13 ENST00000541045.1
ENST00000536908.2
EF-hand calcium binding domain 5
chr19_-_1652575 0.13 ENST00000587235.1
ENST00000262965.5
transcription factor 3
chrX_-_106243294 0.13 ENST00000255495.7
MORC family CW-type zinc finger 4
chr13_-_31039375 0.13 ENST00000399494.1
high mobility group box 1
chr7_-_99774945 0.13 ENST00000292377.2
glypican 2
chr2_-_224702270 0.13 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
adaptor-related protein complex 1, sigma 3 subunit
chr4_-_129209221 0.13 ENST00000512483.1
progesterone receptor membrane component 2
chr6_-_74233480 0.13 ENST00000455918.1
eukaryotic translation elongation factor 1 alpha 1
chr4_-_71705027 0.13 ENST00000545193.1
G-rich RNA sequence binding factor 1
chr11_-_64511789 0.13 ENST00000419843.1
ENST00000394430.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_47546220 0.13 ENST00000528538.1
CUGBP, Elav-like family member 1
chr13_+_42031679 0.13 ENST00000379359.3
regulator of cell cycle
chr19_-_59066327 0.13 ENST00000596708.1
ENST00000601220.1
ENST00000597848.1
charged multivesicular body protein 2A
chr17_+_78075324 0.13 ENST00000570803.1
glucosidase, alpha; acid
chrX_-_54070388 0.13 ENST00000415025.1
PHD finger protein 8
chr20_-_61733657 0.13 ENST00000608031.1
ENST00000447910.2
highly accelerated region 1B (non-protein coding)
chr6_-_114292284 0.13 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
histone deacetylase 2
chr6_-_114292449 0.12 ENST00000519065.1
histone deacetylase 2
chr5_+_63461642 0.12 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
ring finger protein 180
chr19_+_8274512 0.12 ENST00000560412.1
ceramide synthase 4
chr12_+_77158021 0.12 ENST00000550876.1
zinc finger, DHHC-type containing 17
chr2_+_26915584 0.12 ENST00000302909.3
potassium channel, subfamily K, member 3
chr16_-_46865286 0.12 ENST00000285697.4
chromosome 16 open reading frame 87
chr14_+_56046914 0.12 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
kinectin 1 (kinesin receptor)
chr6_-_150346607 0.12 ENST00000367341.1
ENST00000286380.2
retinoic acid early transcript 1L
chr7_-_44365020 0.12 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
calcium/calmodulin-dependent protein kinase II beta
chr12_-_106641728 0.12 ENST00000378026.4
cytoskeleton-associated protein 4
chr6_+_143772060 0.12 ENST00000367591.4
peroxisomal biogenesis factor 3
chr7_-_27239703 0.12 ENST00000222753.4
homeobox A13
chr17_-_57184170 0.12 ENST00000393065.2
tripartite motif containing 37
chr6_+_12012170 0.12 ENST00000487103.1
human immunodeficiency virus type I enhancer binding protein 1
chr1_+_41445413 0.12 ENST00000541520.1
CTP synthase 1
chr8_-_94753184 0.12 ENST00000520560.1
RNA binding motif protein 12B
chr17_+_5973793 0.12 ENST00000317744.5
WSC domain containing 1
chr13_+_37393351 0.12 ENST00000255476.2
regulatory factor X-associated protein
chr15_+_79165296 0.12 ENST00000558746.1
ENST00000558830.1
ENST00000559345.1
mortality factor 4 like 1
chr18_+_48086440 0.12 ENST00000400384.2
ENST00000540640.1
ENST00000592595.1
mitogen-activated protein kinase 4
chr13_+_76123883 0.12 ENST00000377595.3
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr2_+_181845532 0.11 ENST00000602475.1
ubiquitin-conjugating enzyme E2E 3
chr3_+_51422478 0.11 ENST00000528157.1
mesencephalic astrocyte-derived neurotrophic factor
chr8_+_29953163 0.11 ENST00000518192.1
leptin receptor overlapping transcript-like 1
chr14_-_105635090 0.11 ENST00000331782.3
ENST00000347004.2
jagged 2
chr15_+_79165372 0.11 ENST00000558502.1
mortality factor 4 like 1
chr2_-_136743436 0.11 ENST00000441323.1
ENST00000449218.1
aspartyl-tRNA synthetase
chr9_-_3525968 0.11 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
regulatory factor X, 3 (influences HLA class II expression)
chr10_-_105110890 0.11 ENST00000369847.3
polycomb group ring finger 6
chr17_+_7348658 0.11 ENST00000570557.1
ENST00000536404.2
ENST00000576360.1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr9_-_15510989 0.11 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PC4 and SFRS1 interacting protein 1
chr11_-_93474645 0.11 ENST00000532455.1
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
chr15_-_49912987 0.11 ENST00000560246.1
ENST00000558594.1
family with sequence similarity 227, member B
chr9_-_4741217 0.11 ENST00000447596.4
adenylate kinase 3
chr17_+_75137460 0.11 ENST00000587820.1
SEC14-like 1 (S. cerevisiae)
chr1_+_236305826 0.11 ENST00000366592.3
ENST00000366591.4
G protein-coupled receptor 137B
chr15_+_79165222 0.11 ENST00000559930.1
mortality factor 4 like 1
chr2_-_73511559 0.11 ENST00000521871.1
F-box protein 41
chr2_-_120124258 0.11 ENST00000409877.1
ENST00000409523.1
ENST00000409466.2
ENST00000414534.1
chromosome 2 open reading frame 76
chr2_+_9563697 0.11 ENST00000238112.3
cleavage and polyadenylation specific factor 3, 73kDa
chr15_+_41136216 0.11 ENST00000562057.1
ENST00000344051.4
serine peptidase inhibitor, Kunitz type 1
chr9_-_86571628 0.11 ENST00000376344.3
chromosome 9 open reading frame 64
chr19_+_46144884 0.11 ENST00000593161.1
chromosome 19 open reading frame 83
chr1_-_45805752 0.10 ENST00000354383.6
ENST00000355498.2
ENST00000372100.5
ENST00000531105.1
mutY homolog
chr8_-_94753202 0.10 ENST00000521947.1
RNA binding motif protein 12B
chr2_+_149402009 0.10 ENST00000457184.1
enhancer of polycomb homolog 2 (Drosophila)
chr19_+_17392672 0.10 ENST00000594072.1
ENST00000598347.1
ankyrin repeat and LEM domain containing 1
chr2_+_135676381 0.10 ENST00000537343.1
ENST00000295238.6
ENST00000264157.5
cyclin T2
chr2_+_9564013 0.10 ENST00000460593.1
cleavage and polyadenylation specific factor 3, 73kDa
chr19_-_39832563 0.10 ENST00000599274.1
CTC-246B18.10
chr8_-_28243590 0.10 ENST00000523095.1
ENST00000522795.1
zinc finger protein 395
chr1_-_63153944 0.10 ENST00000340370.5
ENST00000404627.2
ENST00000251157.5
dedicator of cytokinesis 7
chr2_+_64681641 0.10 ENST00000409537.2
lectin, galactoside-binding-like
chr2_+_9563769 0.10 ENST00000475482.1
cleavage and polyadenylation specific factor 3, 73kDa
chr12_-_89920030 0.10 ENST00000413530.1
ENST00000547474.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chrX_+_21959108 0.10 ENST00000457085.1
spermine synthase
chr2_+_170655789 0.10 ENST00000409333.1
Sjogren syndrome antigen B (autoantigen La)
chr13_+_52586517 0.10 ENST00000523764.1
ENST00000521508.1
ALG11, alpha-1,2-mannosyltransferase
chr19_+_8274204 0.10 ENST00000561053.1
ENST00000251363.5
ENST00000559450.1
ENST00000559336.1
ceramide synthase 4
chr22_+_20104947 0.10 ENST00000402752.1
RAN binding protein 1
chr20_+_31407692 0.10 ENST00000375571.5
microtubule-associated protein, RP/EB family, member 1
chr5_-_6633397 0.10 ENST00000264670.6
ENST00000539938.1
NOP2/Sun RNA methyltransferase family, member 2
chr19_+_19496728 0.10 ENST00000537887.1
ENST00000417582.2
GATA zinc finger domain containing 2A
chr22_-_50964849 0.10 ENST00000543927.1
ENST00000423348.1
SCO2 cytochrome c oxidase assembly protein
chr10_-_121302195 0.10 ENST00000369103.2
regulator of G-protein signaling 10
chr1_+_207494853 0.10 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chr2_+_54198210 0.10 ENST00000607452.1
ENST00000422521.2
acylphosphatase 2, muscle type
chr2_-_120124383 0.10 ENST00000334816.7
chromosome 2 open reading frame 76
chr3_-_148804275 0.10 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
helicase-like transcription factor
chr2_-_47142884 0.10 ENST00000409105.1
ENST00000409973.1
ENST00000409913.1
ENST00000319466.4
multiple coagulation factor deficiency 2
chr15_-_32162833 0.10 ENST00000560598.1
OTU domain containing 7A
chr9_-_4741255 0.10 ENST00000381809.3
adenylate kinase 3
chr3_+_134205000 0.10 ENST00000512894.1
ENST00000513612.2
ENST00000606977.1
centrosomal protein 63kDa
chr4_+_57302297 0.10 ENST00000399688.3
ENST00000512576.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr9_+_133971909 0.10 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
allograft inflammatory factor 1-like
chr4_+_113152978 0.10 ENST00000309703.6
adaptor-related protein complex 1 associated regulatory protein
chr1_-_205290865 0.10 ENST00000367157.3
NUAK family, SNF1-like kinase, 2
chr7_-_140341251 0.10 ENST00000491728.1
DENN/MADD domain containing 2A
chr8_+_56685701 0.09 ENST00000260129.5
trimethylguanosine synthase 1
chr20_+_61273797 0.09 ENST00000217159.1
solute carrier organic anion transporter family, member 4A1
chr10_+_16478942 0.09 ENST00000535784.2
ENST00000423462.2
ENST00000378000.1
phosphotriesterase related
chr15_-_44069741 0.09 ENST00000319359.3
elongation factor RNA polymerase II-like 3
chr8_-_66754172 0.09 ENST00000401827.3
phosphodiesterase 7A
chr6_+_151646800 0.09 ENST00000354675.6
A kinase (PRKA) anchor protein 12
chr11_-_113746277 0.09 ENST00000003302.4
ENST00000545540.1
ubiquitin specific peptidase 28
chr9_-_124976185 0.09 ENST00000464484.2
LIM homeobox 6
chr12_+_122064673 0.09 ENST00000537188.1
ORAI calcium release-activated calcium modulator 1
chr9_-_86153218 0.09 ENST00000304195.3
ENST00000376438.1
FERM domain containing 3
chr7_-_105925558 0.09 ENST00000222553.3
nicotinamide phosphoribosyltransferase
chr7_-_6098770 0.09 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
eukaryotic translation initiation factor 2-alpha kinase 1
chr6_-_105850937 0.09 ENST00000369110.3
prolyl endopeptidase
chr6_+_86159765 0.09 ENST00000369646.3
ENST00000257770.3
5'-nucleotidase, ecto (CD73)
chr3_-_185542761 0.09 ENST00000457616.2
ENST00000346192.3
insulin-like growth factor 2 mRNA binding protein 2
chr9_+_33025209 0.09 ENST00000330899.4
ENST00000544625.1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr1_-_8086343 0.09 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERBB receptor feedback inhibitor 1
chr12_-_107487604 0.09 ENST00000008527.5
cryptochrome 1 (photolyase-like)
chr2_+_29117509 0.09 ENST00000407426.3
WD repeat domain 43
chr13_-_51417812 0.09 ENST00000504404.1
deleted in lymphocytic leukemia, 7
chr2_-_200715573 0.09 ENST00000420922.2
formiminotransferase cyclodeaminase N-terminal like
chr11_-_113746212 0.09 ENST00000537642.1
ENST00000537706.1
ENST00000544750.1
ENST00000260188.5
ENST00000540925.1
ubiquitin specific peptidase 28
chr8_-_101348408 0.09 ENST00000519527.1
ENST00000522369.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr7_+_151038785 0.09 ENST00000413040.2
ENST00000568733.1
negative regulator of ubiquitin-like proteins 1
chr3_-_112738490 0.09 ENST00000393857.2
chromosome 3 open reading frame 17
chr13_-_102068706 0.09 ENST00000251127.6
sodium leak channel, non-selective
chr1_-_41707778 0.09 ENST00000337495.5
ENST00000372597.1
ENST00000372596.1
sex comb on midleg homolog 1 (Drosophila)
chr14_+_93260569 0.09 ENST00000163416.2
golgin A5
chr3_-_185542817 0.09 ENST00000382199.2
insulin-like growth factor 2 mRNA binding protein 2
chr15_+_73344911 0.09 ENST00000560262.1
ENST00000558964.1
neogenin 1
chr9_+_133971863 0.09 ENST00000372309.3
allograft inflammatory factor 1-like

Network of associatons between targets according to the STRING database.

First level regulatory network of HES1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2 0.8 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.4 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.1 0.2 GO:0046041 ITP metabolic process(GO:0046041)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.2 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.3 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.3 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.2 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.2 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.4 GO:0045007 depurination(GO:0045007)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:0043181 vacuolar sequestering(GO:0043181)
0.0 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.3 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.2 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.0 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.1 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0051300 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.1 GO:1903998 regulation of eating behavior(GO:1903998)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.0 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.1 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.0 0.2 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.0 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.1 GO:0008355 olfactory learning(GO:0008355)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.0 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.0 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.1 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.0 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.2 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.0 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.0 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:2000619 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.0 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:2000323 glucocorticoid secretion(GO:0035933) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) regulation of glucocorticoid secretion(GO:2000849)
0.0 0.0 GO:0035623 renal glucose absorption(GO:0035623)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.0 GO:0002572 pro-T cell differentiation(GO:0002572) regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.1 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.4 GO:0016768 spermine synthase activity(GO:0016768)
0.1 0.4 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.0 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.0 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis