Project
A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for ELK4_ETV5_ELK1_ELK3_ELF4
Z-value: 2.65
Motif logo
Transcription factors associated with ELK4_ETV5_ELK1_ELK3_ELF4
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSG00000158711.9 | ETS transcription factor ELK4 | |
| ENSG00000244405.3 | ETS variant transcription factor 5 | |
| ENSG00000126767.13 | ETS transcription factor ELK1 | |
| ENSG00000111145.3 | ETS transcription factor ELK3 | |
| ENSG00000102034.12 | E74 like ETS transcription factor 4 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ELK1 | hg19_v2_chrX_-_47509887_47509990 | -0.85 | 3.3e-02 | Click! |
| ELF4 | hg19_v2_chrX_-_129244655_129244697 | -0.84 | 3.5e-02 | Click! |
| ELK3 | hg19_v2_chr12_+_96588143_96588185 | 0.62 | 1.8e-01 | Click! |
| ETV5 | hg19_v2_chr3_-_185826286_185826464 | -0.57 | 2.3e-01 | Click! |
| ELK4 | hg19_v2_chr1_-_205601064_205601090 | 0.30 | 5.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_169337172 Show fit | 4.20 |
ENST00000367807.3
ENST00000367808.3 ENST00000329281.2 ENST00000420531.1 |
basic leucine zipper nuclear factor 1 |
|
| chr7_-_108209897 Show fit | 4.06 |
ENST00000313516.5
|
THAP domain containing 5 |
|
| chr12_+_100594557 Show fit | 3.89 |
ENST00000546902.1
ENST00000552376.1 ENST00000551617.1 |
ARP6 actin-related protein 6 homolog (yeast) |
|
| chr5_+_158690089 Show fit | 3.82 |
ENST00000296786.6
|
ubiquitin-like domain containing CTD phosphatase 1 |
|
| chr1_+_169337412 Show fit | 3.78 |
ENST00000426663.1
|
basic leucine zipper nuclear factor 1 |
|
| chr21_+_42792442 Show fit | 3.48 |
ENST00000398600.2
|
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) |
|
| chr20_-_49575081 Show fit | 3.44 |
ENST00000371588.5
ENST00000371582.4 |
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit |
|
| chr1_-_222886526 Show fit | 3.28 |
ENST00000541237.1
|
axin interactor, dorsalization associated |
|
| chr4_-_153700864 Show fit | 3.23 |
ENST00000304337.2
|
tigger transposable element derived 4 |
|
| chr15_+_71185148 Show fit | 3.08 |
ENST00000443425.2
ENST00000560755.1 |
leucine rich repeat containing 49 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ELK4_ETV5_ELK1_ELK3_ELF4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.2 | 7.1 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.1 | 7.1 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.9 | 6.9 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.2 | 6.7 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 0.5 | 6.1 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.2 | 6.0 | GO:0051383 | kinetochore organization(GO:0051383) |
| 0.2 | 6.0 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.1 | 5.9 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.8 | 5.8 | GO:0019348 | dolichol metabolic process(GO:0019348) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 17.3 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 15.5 | GO:0005813 | centrosome(GO:0005813) |
| 0.0 | 8.3 | GO:0031965 | nuclear membrane(GO:0031965) |
| 1.3 | 7.7 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 0.0 | 7.4 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.3 | 7.3 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.5 | 6.6 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.1 | 6.3 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 5.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 1.4 | 5.4 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 9.5 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.2 | 8.2 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.5 | 6.8 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.1 | 6.7 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.1 | 6.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.5 | 5.5 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 1.4 | 5.4 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.1 | 5.0 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.1 | 4.9 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.2 | 4.8 | GO:0042609 | CD4 receptor binding(GO:0042609) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 17.6 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.2 | 6.7 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 5.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 4.6 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 4.5 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 4.0 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 3.6 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 3.6 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 3.5 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 3.2 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 16.2 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.2 | 15.8 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 11.1 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.2 | 9.7 | REACTOME RNA POL I TRANSCRIPTION INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
| 0.3 | 9.4 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.1 | 9.4 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.3 | 9.2 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.1 | 9.0 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.2 | 7.2 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.4 | 6.5 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |