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Results for YRM1

Z-value: 0.78

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Transcription factors associated with YRM1

Gene Symbol Gene ID Gene Info
YRM1
S000005698 Zinc-finger transcription factor involved in multidrug resistance

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
YRM1YOR172W-0.423.5e-02Click!

Activity profile of YRM1 motif

Sorted Z-values of YRM1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YFR055W 16.63
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YFR056C 15.15 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YHR094C 10.95
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YER131W 9.90
RPS26B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein
YKR075C 8.57 Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YDR033W 7.69
MRH1
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p
YMR102C 7.56 Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene
YDR345C 7.24
HXT3
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
YDR044W 7.00
HEM13
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)
YLR154C 6.77
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YGL209W 5.99
MIG2
Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
YIL056W 5.72
VHR1
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations
YPL250W-A 5.55 Identified by fungal homology and RT-PCR
YJR063W 5.34
RPA12
RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex
YIL118W 5.26
RHO3
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
YLR154W-B 5.03 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YDR279W 4.88
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YLR154W-A 4.84 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YDR002W 4.78
YRB1
Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1
YLR180W 4.77
SAM1
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)
YPL137C 4.61
GIP3
Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments
YIR021W 4.61
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YKL218C 4.57
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YHR128W 4.27
FUR1
Uracil phosphoribosyltransferase, synthesizes UMP from uracil; involved in the pyrimidine salvage pathway
YNL178W 4.19
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YJR094W-A 4.15
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YOR051C 4.14 Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
YEL027W 4.04
CUP5
Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohexylcarbodiimide binding subunit); required for vacuolar acidification and important for copper and iron metal ion homeostasis
YKL096W-A 3.98
CWP2
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored
YHR141C 3.98
RPL42B
Protein component of the large (60S) ribosomal subunit, identical to Rpl42Ap and has similarity to rat L44; required for propagation of the killer toxin-encoding M1 double-stranded RNA satellite of the L-A double-stranded RNA virus
YGL055W 3.76
OLE1
Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria
YGL157W 3.76 Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)
YGR280C 3.72
PXR1
Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain
YKL063C 3.64 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
YBR158W 3.64
AMN1
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YLR110C 3.61
CCW12
Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor
YOR315W 3.55
SFG1
Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate
YER130C 3.54 Hypothetical protein
YOR101W 3.52
RAS1
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes
YML043C 3.46
RRN11
Protein required for rDNA transcription by RNA polymerase I, component of the core factor (CF) of rDNA transcription factor, which also contains Rrn6p and Rrn7p
YOL086C 3.44
ADH1
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
YEL029C 3.43
BUD16
Putative pyridoxal kinase, key enzyme in vitamin B6 metabolism; involved in maintaining levels of pyridoxal 5'-phosphate, the active form of vitamin B6; required for genome integrity; homolog of E. coli PdxK; involved in bud-site selection
YPL256C 3.35
CLN2
G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
YLR301W 3.33 Protein of unknown function that interacts with Sec72p
YGR052W 3.29
FMP48
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation
YOR047C 3.28
STD1
Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p
YFR054C 3.26 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YNR001W-A 3.24 Dubious open reading frame unlikely to encode a functional protein; identified by homology
YOR163W 3.24
DDP1
Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; has high specificity for diadenosine hexa- and pentaphosphates; member of the MutT family of nucleotide hydrolases
YGR234W 3.23
YHB1
Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses
YKL052C 3.15
ASK1
Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases
YOR063W 3.11
RPL3
Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
YKR038C 3.07
KAE1
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex
YJL158C 3.07
CIS3
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
YKL051W 2.93
SFK1
Plasma membrane protein that may act together with or upstream of Stt4p to generate normal levels of the essential phospholipid PI4P, at least partially mediates proper localization of Stt4p to the plasma membrane
YLR328W 2.88
NMA1
Nicotinic acid mononucleotide adenylyltransferase, involved in pathways of NAD biosynthesis, including the de novo, NAD(+) salvage, and nicotinamide riboside salvage pathways
YOR376W-A 2.86 Putative protein of unknown function; identified by fungal homology and RT-PCR
YOR028C 2.77
CIN5
Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus
YER124C 2.70
DSE1
Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall
YMR083W 2.69
ADH3
Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production
YAL038W 2.69
CDC19
Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration
YDR072C 2.69
IPT1
Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media
YHL028W 2.65
WSC4
ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3
YIL169C 2.61 Putative protein of unknown function; serine/threonine rich and highly similar to YOL155C, a putative glucan alpha-1,4-glucosidase; transcript is induced in both high and low pH environments; YIL169C is a non-essential gene
YDL075W 2.61
RPL31A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YMR009W 2.60
ADI1
Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; transcribed with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions
YOR029W 2.60 Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data
YDR502C 2.58
SAM2
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)
YPL136W 2.57 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified gene GIP3/YPL137C
YGR034W 2.47
RPL26B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA
YDL023C 2.47 Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance
YCR035C 2.45
RRP43
Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex with Rrp41p, Rrp42p, Rrp4p and Dis3p; required for efficient maturation of 5.8S, 18S and 25S rRNA
YDL047W 2.41
SIT4
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
YKL110C 2.38
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YER043C 2.37
SAH1
S-adenosyl-L-homocysteine hydrolase, catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor
YIL076W 2.37
SEC28
Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth
YGR050C 2.37 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YPR074C 2.37
TKL1
Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
YNR018W 2.36
AIM38
Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
YHR163W 2.25
SOL3
6-phosphogluconolactonase, catalyzes the second step of the pentose phosphate pathway; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p
YOR375C 2.22
GDH1
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources
YER028C 2.18
MIG3
Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes
YML088W 2.17
UFO1
F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation
YHR208W 2.16
BAT1
Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase
YMR123W 2.16
PKR1
V-ATPase assembly factor, functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0); overproduction confers resistance to Pichia farinosa killer toxin
YLL044W 2.15 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLL044W and the overlapping gene RPL8B is reduced in the gcr1 null mutant
YOR226C 2.14
ISU2
Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable
YEL040W 2.12
UTR2
Cell wall protein that functions in the transfer of chitin to beta(1-6)glucan; putative chitin transglycosidase; glycosylphosphatidylinositol (GPI)-anchored protein localized to the bud neck; has a role in cell wall maintenance
YMR217W 2.11
GUA1
GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation
YNL118C 2.11
DCP2
Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; member of the Nudix hydrolase family
YLR179C 2.07 Protein of unknown function, transcription is activated by paralogous proteins Yrm1p and Yrr1p along with proteins involved in multidrug resistance; GFP-tagged protein localizes to the cytoplasm and nucleus; YLR179C is not essential
YGR251W 2.06 Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene
YDR346C 2.06
SVF1
Protein with a potential role in cell survival pathways, required for the diauxic growth shift; expression in mammalian cells increases survival under conditions inducing apoptosis
YBR238C 2.06 Mitochondrial membrane protein with similarity to Rmd9p; not required for respiratory growth but causes a synthetic respiratory defect in combination with rmd9 mutations; transcriptionally up-regulated by TOR; deletion increases life span
YEL068C 2.06 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YBL085W 2.05
BOI1
Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
YDL022W 2.05
GPD1
NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p
YDR041W 2.03
RSM10
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins
YOR050C 2.02 Hypothetical protein
YLR154W-C 2.02
TAR1
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand
YDR074W 2.01
TPS2
Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway
YKL154W 2.01
SRP102
Signal recognition particle (SRP) receptor beta subunit; involved in SRP-dependent protein targeting; anchors Srp101p to the ER membrane
YPR119W 2.01
CLB2
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YMR205C 1.98
PFK2
Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes
YJL011C 1.97
RPC17
RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex
YBR151W 1.97
APD1
Protein of unknown function, required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus
YMR121C 1.96
RPL15B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA
YGL158W 1.93
RCK1
Protein kinase involved in the response to oxidative stress; identified as suppressor of S. pombe cell cycle checkpoint mutations
YDL022C-A 1.92 Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene DIA3; identified by fungal homology and RT-PCR
YGR051C 1.92 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene
YGL097W 1.91
SRM1
Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p
YIL121W 1.90
QDR2
Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake
YLR257W 1.90 Putative protein of unknown function
YJR057W 1.89
CDC8
Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p
YKR041W 1.86 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YPL197C 1.86 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the ribosomal gene RPB7B
YLR453C 1.85
RIF2
Protein that binds to the Rap1p C-terminus and acts synergistically with Rif1p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation
YKL081W 1.85
TEF4
Translation elongation factor EF-1 gamma
YPR010C 1.83
RPA135
RNA polymerase I subunit A135
YMR001C-A 1.83 Putative protein of unknown function
YGR017W 1.82 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm
YMR015C 1.82
ERG5
C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs
YDR073W 1.82
SNF11
Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; interacts with a highly conserved 40-residue sequence of Snf2p
YER055C 1.81
HIS1
ATP phosphoribosyltransferase, a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control
YPL198W 1.79
RPL7B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Ap and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)
YKL182W 1.79
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YPR157W 1.76 Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation
YDR399W 1.76
HPT1
Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
YOL124C 1.75
TRM11
Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain
YBR038W 1.74
CHS2
Chitin synthase II, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for the synthesis of chitin in the primary septum during cytokinesis
YDR344C 1.74 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YLR075W 1.73
RPL10
Protein component of the large (60S) ribosomal subunit, responsible for joining the 40S and 60S subunits; regulates translation initiation; has similarity to rat L10 ribosomal protein and to members of the QM gene family
YJL157C 1.72
FAR1
Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate
YDR095C 1.71 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YNL327W 1.71
EGT2
Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner
YLL045C 1.69
RPL8B
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
YER023C-A 1.69 Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene PRO3; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching
YLR285W 1.68
NNT1
Putative nicotinamide N-methyltransferase, has a role in rDNA silencing and in lifespan determination
YJR105W 1.67
ADO1
Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle
YHR149C 1.67
SKG6
Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p
YDR098C 1.66
GRX3
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
YDR040C 1.65
ENA1
P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
YHR148W 1.65
IMP3
Component of the SSU processome, which is required for pre-18S rRNA processing, essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA
YER137C 1.64 Putative protein of unknown function
YDR454C 1.62
GUK1
Guanylate kinase, converts GMP to GDP; required for growth and mannose outer chain elongation of cell wall N-linked glycoproteins
YDR094W 1.62 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF DNF2
YMR106C 1.62
YKU80
Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
YDR509W 1.60 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YJR069C 1.59
HAM1
Conserved protein with deoxyribonucleoside triphosphate pyrophosphohydrolase activity, mediates exclusion of noncanonical purines from deoxyribonucleoside triphosphate pools; mutant is sensitive to the base analog 6-N-hydroxylaminopurine
YJL107C 1.59 Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi
YPR170W-B 1.58 Putative protein of unknown function, conserved in fungi; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C
YIL009W 1.55
FAA3
Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YCR006C 1.53 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YDR133C 1.52 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C
YDR508C 1.51
GNP1
High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids
YDR278C 1.51 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOL085C 1.50 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOL085W-A
YHR047C 1.50
AAP1
Arginine/alanine aminopeptidase, overproduction stimulates glycogen accumulation
YML075C 1.49
HMG1
One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae
YGL009C 1.49
LEU1
Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway
YEL066W 1.48
HPA3
D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro
YOL101C 1.47
IZH4
Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism
YLR129W 1.47
DIP2
Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex
YKL219W 1.46
COS9
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
YKL166C 1.46
TPK3
cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk2p
YBR087W 1.45
RFC5
Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
YNL065W 1.45
AQR1
Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids
YPL143W 1.43
RPL33A
N-terminally acetylated ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Bp and has similarity to rat L35a; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable
YDL048C 1.42
STP4
Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p
YHR201C 1.41
PPX1
Exopolyphosphatase, hydrolyzes inorganic polyphosphate (poly P) into Pi residues; located in the cytosol, plasma membrane, and mitochondrial matrix
YMR011W 1.41
HXT2
High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose
YHR216W 1.40
IMD2
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation
YPL012W 1.40
RRP12
Protein required for export of the ribosomal subunits; associates with the RNA components of the pre-ribosomes; contains HEAT-repeats
YOR319W 1.40
HSH49
U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM)
YPL183C 1.38
RTT10
Cytoplasmic protein with a role in regulation of Ty1 transposition
YER036C 1.36
ARB1
ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome biogenesis, has similarity to Gcn20p; shuttles from nucleus to cytoplasm, physically interacts with Tif6p, Lsg1p
YIL009C-A 1.36
EST3
Component of the telomerase holoenzyme, involved in telomere replication
YCL064C 1.35
CHA1
Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine
YER048W-A 1.35
ISD11
Protein required for mitochondrial iron-sulfur cluster biosynthesis
YDL082W 1.35
RPL13A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Bp; not essential for viability; has similarity to rat L13 ribosomal protein
YCL063W 1.34
VAC17
Protein involved in vacuole inheritance; acts as a vacuole-specific receptor for myosin Myo2p
YAL003W 1.34
EFB1
Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site
YEL053W-A 1.34 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YEL054C
YGR155W 1.34
CYS4
Cystathionine beta-synthase, catalyzes the synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis
YBR257W 1.33
POP4
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in Rnase P
YOR030W 1.33
DFG16
Probable multiple transmembrane protein, involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; required for accumulation of processed Rim101p
YBR137W 1.33 Protein of unknown function; localized to the cytoplasm; binds to Replication Protein A (RPA); YBR137W is not an essential gene
YNL090W 1.31
RHO2
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involved in the establishment of cell polarity and in microtubule assembly
YDL083C 1.31
RPS16B
Protein component of the small (40S) ribosomal subunit; identical to Rps16Ap and has similarity to E. coli S9 and rat S16 ribosomal proteins
YMR108W 1.31
ILV2
Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control
YIL053W 1.30
RHR2
Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress
YGR148C 1.30
RPL24B
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YEL056W 1.30
HAT2
Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing
YMR049C 1.29
ERB1
Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
YLR100W 1.29
ERG27
3-keto sterol reductase, catalyzes the last of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants are sterol auxotrophs
YDR534C 1.29
FIT1
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall
YBR256C 1.28
RIB5
Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway
YMR290W-A 1.28 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase
YGR192C 1.28
TDH3
Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall
YPR170W-A 1.28 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by expression profiling and mass spectrometry

Network of associatons between targets according to the STRING database.

First level regulatory network of YRM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.5 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
2.0 7.9 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
1.7 12.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
1.5 4.6 GO:0006798 polyphosphate catabolic process(GO:0006798)
1.4 5.5 GO:0036170 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
1.3 5.4 GO:0090337 regulation of formin-nucleated actin cable assembly(GO:0090337) positive regulation of formin-nucleated actin cable assembly(GO:0090338)
1.3 7.7 GO:0046037 GMP metabolic process(GO:0046037)
1.2 3.7 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
1.2 4.9 GO:0014070 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
1.2 3.5 GO:0033559 unsaturated fatty acid biosynthetic process(GO:0006636) unsaturated fatty acid metabolic process(GO:0033559)
1.1 20.4 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
1.1 4.4 GO:0043097 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
1.1 4.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
1.1 3.3 GO:0046495 nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637)
1.1 7.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
1.0 3.1 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
1.0 4.1 GO:0007157 agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
1.0 5.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
1.0 1.9 GO:0009409 response to cold(GO:0009409) cellular response to cold(GO:0070417)
0.9 3.8 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.8 1.7 GO:0000751 mitotic cell cycle arrest in response to pheromone(GO:0000751) mitotic cell cycle arrest(GO:0071850)
0.8 1.5 GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461)
0.8 2.3 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.7 2.6 GO:0051597 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
0.7 6.6 GO:0006116 NADH oxidation(GO:0006116)
0.7 2.0 GO:0071482 cellular response to radiation(GO:0071478) cellular response to light stimulus(GO:0071482)
0.6 4.3 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.6 3.7 GO:0009099 valine biosynthetic process(GO:0009099)
0.6 2.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.6 1.7 GO:0000916 actomyosin contractile ring contraction(GO:0000916) contractile ring contraction(GO:0036213)
0.6 2.3 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.6 2.9 GO:0043102 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.5 1.6 GO:0006567 threonine catabolic process(GO:0006567)
0.5 2.2 GO:0000296 spermine transport(GO:0000296)
0.5 1.6 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.5 4.5 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.5 5.5 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
0.5 2.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.5 4.0 GO:0000376 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.5 1.5 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.5 1.4 GO:0035953 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
0.5 2.3 GO:0006110 regulation of glycolytic process(GO:0006110)
0.5 1.4 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.4 2.2 GO:0006673 inositolphosphoceramide metabolic process(GO:0006673)
0.4 1.7 GO:0007535 donor selection(GO:0007535)
0.4 2.6 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) aldehyde biosynthetic process(GO:0046184)
0.4 57.4 GO:0002181 cytoplasmic translation(GO:0002181)
0.4 2.9 GO:0048017 inositol lipid-mediated signaling(GO:0048017)
0.4 1.6 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.4 3.5 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.4 0.8 GO:0070649 parallel actin filament bundle assembly(GO:0030046) formin-nucleated actin cable assembly(GO:0070649)
0.4 0.4 GO:1902931 negative regulation of alcohol biosynthetic process(GO:1902931)
0.4 1.9 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.4 0.7 GO:0000092 mitotic anaphase B(GO:0000092)
0.4 2.6 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
0.4 0.7 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.3 1.0 GO:0038032 termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.3 1.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.3 0.7 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.3 1.7 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.3 1.3 GO:0050667 transsulfuration(GO:0019346) homocysteine metabolic process(GO:0050667)
0.3 4.7 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.3 1.0 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.3 1.6 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.3 2.2 GO:0005992 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
0.3 1.6 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.3 4.6 GO:0006037 cell wall chitin metabolic process(GO:0006037)
0.3 0.9 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.3 1.2 GO:0030497 fatty acid elongation(GO:0030497)
0.3 0.9 GO:0008272 sulfate transport(GO:0008272)
0.3 4.3 GO:0001100 negative regulation of exit from mitosis(GO:0001100)
0.3 2.3 GO:0006901 vesicle coating(GO:0006901)
0.3 1.4 GO:0009098 leucine biosynthetic process(GO:0009098)
0.3 1.7 GO:0006021 inositol biosynthetic process(GO:0006021)
0.3 0.3 GO:0006549 isoleucine metabolic process(GO:0006549)
0.3 0.8 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.3 4.2 GO:0071051 nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.3 1.7 GO:0090158 regulation of phosphatidylinositol dephosphorylation(GO:0060304) endoplasmic reticulum membrane organization(GO:0090158)
0.3 0.5 GO:1902223 L-phenylalanine biosynthetic process(GO:0009094) erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process(GO:1902223)
0.3 0.8 GO:0032006 regulation of TOR signaling(GO:0032006)
0.3 1.9 GO:0016233 telomere capping(GO:0016233)
0.3 4.6 GO:0009304 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.3 6.1 GO:0044108 ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384)
0.3 0.3 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.2 0.5 GO:0031555 transcriptional attenuation(GO:0031555) transcription antitermination(GO:0031564)
0.2 2.2 GO:0034965 intronic snoRNA processing(GO:0031070) intronic box C/D snoRNA processing(GO:0034965)
0.2 2.0 GO:0000321 re-entry into mitotic cell cycle after pheromone arrest(GO:0000321)
0.2 1.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.2 1.0 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.2 2.6 GO:0009435 NAD biosynthetic process(GO:0009435)
0.2 1.2 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.2 0.9 GO:0015883 FAD transport(GO:0015883)
0.2 0.5 GO:1901880 regulation of protein depolymerization(GO:1901879) negative regulation of protein depolymerization(GO:1901880)
0.2 5.5 GO:0006885 regulation of pH(GO:0006885)
0.2 1.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 1.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.2 2.3 GO:0000921 septin ring assembly(GO:0000921)
0.2 2.5 GO:0006415 translational termination(GO:0006415)
0.2 1.2 GO:0006491 N-glycan processing(GO:0006491)
0.2 2.0 GO:0006272 leading strand elongation(GO:0006272)
0.2 2.7 GO:0030488 tRNA methylation(GO:0030488)
0.2 6.1 GO:0045047 protein targeting to ER(GO:0045047)
0.2 2.0 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 0.6 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.2 1.5 GO:0061572 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.2 1.9 GO:0052803 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.2 4.8 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.2 1.7 GO:0042766 nucleosome mobilization(GO:0042766)
0.2 0.8 GO:0007234 osmosensory signaling via phosphorelay pathway(GO:0007234)
0.2 2.6 GO:0006972 hyperosmotic response(GO:0006972)
0.2 2.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 4.0 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 0.4 GO:0010922 positive regulation of phosphatase activity(GO:0010922)
0.2 0.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.2 2.3 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.2 0.7 GO:0060188 regulation of protein desumoylation(GO:0060188)
0.2 3.5 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.2 0.5 GO:0009097 isoleucine biosynthetic process(GO:0009097)
0.2 0.5 GO:0015809 arginine transport(GO:0015809)
0.2 0.8 GO:0006563 L-serine metabolic process(GO:0006563)
0.2 0.2 GO:0019357 nicotinate nucleotide biosynthetic process(GO:0019357) nicotinate nucleotide salvage(GO:0019358) pyridine nucleotide salvage(GO:0019365) nicotinate nucleotide metabolic process(GO:0046497)
0.2 0.3 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 2.4 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 0.9 GO:0046513 ceramide metabolic process(GO:0006672) ceramide biosynthetic process(GO:0046513)
0.1 0.4 GO:0051457 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674) maintenance of protein location in nucleus(GO:0051457)
0.1 0.7 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1 0.9 GO:0000743 nuclear migration involved in conjugation with cellular fusion(GO:0000743)
0.1 1.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.4 GO:0090220 meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.1 0.1 GO:0043244 regulation of protein complex disassembly(GO:0043244)
0.1 4.0 GO:0006414 translational elongation(GO:0006414)
0.1 0.1 GO:0051439 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.5 GO:0009371 positive regulation of transcription from RNA polymerase II promoter by pheromones(GO:0007329) positive regulation of transcription by pheromones(GO:0009371)
0.1 0.4 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 4.0 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.8 GO:0000032 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506)
0.1 2.3 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 0.5 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 0.1 GO:1900062 regulation of cell aging(GO:0090342) regulation of replicative cell aging(GO:1900062)
0.1 0.5 GO:0015867 ATP transport(GO:0015867)
0.1 0.8 GO:0048478 replication fork protection(GO:0048478)
0.1 0.1 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 0.9 GO:0006771 riboflavin metabolic process(GO:0006771) riboflavin biosynthetic process(GO:0009231)
0.1 0.1 GO:1900544 positive regulation of nucleotide metabolic process(GO:0045981) positive regulation of purine nucleotide metabolic process(GO:1900544)
0.1 4.3 GO:0051170 protein import into nucleus(GO:0006606) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593)
0.1 0.6 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 0.2 GO:2000883 starch metabolic process(GO:0005982) starch catabolic process(GO:0005983) regulation of starch catabolic process by regulation of transcription from RNA polymerase II promoter(GO:0035956) positive regulation of starch catabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0035957) regulation of starch catabolic process(GO:2000881) positive regulation of starch catabolic process(GO:2000883) regulation of starch metabolic process(GO:2000904) positive regulation of starch metabolic process(GO:2000906)
0.1 1.3 GO:0007120 axial cellular bud site selection(GO:0007120)
0.1 1.8 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.1 0.6 GO:0035376 sterol import(GO:0035376)
0.1 0.3 GO:0043171 peptide catabolic process(GO:0043171)
0.1 3.1 GO:0046031 purine nucleoside diphosphate metabolic process(GO:0009135) purine ribonucleoside diphosphate metabolic process(GO:0009179) ribonucleoside diphosphate metabolic process(GO:0009185) ADP metabolic process(GO:0046031)
0.1 0.7 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:0043471 regulation of carbohydrate catabolic process(GO:0043470) regulation of cellular carbohydrate catabolic process(GO:0043471)
0.1 1.0 GO:0055069 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.1 0.7 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 1.2 GO:0000011 vacuole inheritance(GO:0000011)
0.1 0.8 GO:0006641 neutral lipid metabolic process(GO:0006638) acylglycerol metabolic process(GO:0006639) triglyceride metabolic process(GO:0006641)
0.1 0.4 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.1 0.4 GO:0048313 Golgi inheritance(GO:0048313)
0.1 0.4 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 0.6 GO:0019933 cAMP-mediated signaling(GO:0019933) cyclic-nucleotide-mediated signaling(GO:0019935)
0.1 2.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.2 GO:0031106 septin ring organization(GO:0031106)
0.1 0.1 GO:0033239 negative regulation of cellular amine metabolic process(GO:0033239)
0.1 0.4 GO:0043489 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.1 0.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:0009088 threonine metabolic process(GO:0006566) threonine biosynthetic process(GO:0009088)
0.1 0.2 GO:0006734 NADH metabolic process(GO:0006734)
0.1 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473)
0.1 9.1 GO:0006364 rRNA processing(GO:0006364)
0.1 0.8 GO:0015833 peptide transport(GO:0015833)
0.1 0.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 2.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 0.2 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 1.2 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.3 GO:0048279 vesicle fusion with endoplasmic reticulum(GO:0048279)
0.1 0.8 GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay(GO:0070481)
0.1 4.3 GO:0016311 dephosphorylation(GO:0016311)
0.1 0.6 GO:0030026 cellular manganese ion homeostasis(GO:0030026) manganese ion homeostasis(GO:0055071)
0.1 0.7 GO:0090529 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529)
0.1 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.1 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.1 0.2 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.4 GO:0042435 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.1 0.9 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 0.2 GO:0045014 negative regulation of transcription from RNA polymerase II promoter by glucose(GO:0000433) negative regulation of transcription by glucose(GO:0045014)
0.1 0.8 GO:0051050 positive regulation of transport(GO:0051050)
0.1 2.0 GO:0051445 regulation of meiotic nuclear division(GO:0040020) regulation of meiotic cell cycle(GO:0051445)
0.1 0.7 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.1 0.1 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) regulation of membrane lipid metabolic process(GO:1905038)
0.1 0.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 0.1 GO:0009090 homoserine biosynthetic process(GO:0009090)
0.1 0.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 0.7 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.1 2.5 GO:0008033 tRNA processing(GO:0008033)
0.1 0.4 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.1 0.2 GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.1 0.3 GO:0034503 protein localization to nucleolar rDNA repeats(GO:0034503)
0.1 0.5 GO:0030011 maintenance of cell polarity(GO:0030011)
0.1 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 1.2 GO:0009267 cellular response to starvation(GO:0009267)
0.1 0.3 GO:0009423 chorismate biosynthetic process(GO:0009423) chorismate metabolic process(GO:0046417)
0.1 0.8 GO:0030474 spindle pole body duplication(GO:0030474)
0.1 0.1 GO:0030541 plasmid partitioning(GO:0030541)
0.1 0.1 GO:0051300 microtubule organizing center organization(GO:0031023) spindle pole body organization(GO:0051300)
0.1 1.6 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.3 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.1 0.5 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.3 GO:0072337 modified amino acid transport(GO:0072337)
0.1 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 1.3 GO:0007015 actin filament organization(GO:0007015)
0.0 0.1 GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)(GO:0000388)
0.0 0.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.2 GO:1901658 nucleoside catabolic process(GO:0009164) glycosyl compound catabolic process(GO:1901658)
0.0 0.2 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0006797 polyphosphate metabolic process(GO:0006797)
0.0 0.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.4 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.1 GO:0010978 gene silencing involved in chronological cell aging(GO:0010978) gene silencing by RNA(GO:0031047)
0.0 0.8 GO:0009247 GPI anchor biosynthetic process(GO:0006506) glycolipid biosynthetic process(GO:0009247)
0.0 0.4 GO:0051666 actin cortical patch localization(GO:0051666)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0009309 amine biosynthetic process(GO:0009309) cellular biogenic amine biosynthetic process(GO:0042401)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.0 0.2 GO:0010970 establishment of localization by movement along microtubule(GO:0010970) nuclear migration along microtubule(GO:0030473) organelle transport along microtubule(GO:0072384)
0.0 0.2 GO:0015758 glucose transport(GO:0015758)
0.0 0.3 GO:0007009 plasma membrane organization(GO:0007009)
0.0 0.2 GO:0009749 response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0 0.1 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.1 GO:0090282 positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.0 0.0 GO:0030307 positive regulation of cell growth(GO:0030307) positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter(GO:1900461) positive regulation of pseudohyphal growth(GO:2000222)
0.0 0.1 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.1 GO:0042558 folic acid-containing compound metabolic process(GO:0006760) pteridine-containing compound metabolic process(GO:0042558)
0.0 1.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0009411 response to UV(GO:0009411)
0.0 0.3 GO:0048278 vesicle docking(GO:0048278)
0.0 0.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0006284 base-excision repair(GO:0006284)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 1.0 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.0 GO:0031684 heterotrimeric G-protein complex cycle(GO:0031684)
0.0 0.1 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.2 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.3 GO:0072524 pyridine-containing compound metabolic process(GO:0072524)
0.0 0.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.0 GO:0006784 heme a biosynthetic process(GO:0006784) heme a metabolic process(GO:0046160)
0.0 0.0 GO:0033241 regulation of cellular amine catabolic process(GO:0033241)
0.0 0.1 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.0 GO:0046834 lipid phosphorylation(GO:0046834) phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.4 GO:0051169 nuclear transport(GO:0051169)
0.0 0.0 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072) negative regulation of phospholipid metabolic process(GO:1903726)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.9 3.5 GO:0070860 RNA polymerase I core factor complex(GO:0070860)
0.7 3.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.6 3.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.6 52.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.6 8.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.6 1.7 GO:0030428 cell septum(GO:0030428)
0.6 2.2 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
0.5 1.6 GO:0034457 Mpp10 complex(GO:0034457)
0.5 3.8 GO:0072686 mitotic spindle(GO:0072686)
0.5 0.5 GO:0005940 septin ring(GO:0005940)
0.5 1.5 GO:0070545 PeBoW complex(GO:0070545)
0.5 30.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 3.6 GO:0000144 cellular bud neck septin ring(GO:0000144)
0.4 2.2 GO:0000136 alpha-1,6-mannosyltransferase complex(GO:0000136)
0.4 3.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 2.4 GO:0034455 t-UTP complex(GO:0034455)
0.3 2.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.3 1.6 GO:0031391 DNA replication factor C complex(GO:0005663) Rad17 RFC-like complex(GO:0031389) Elg1 RFC-like complex(GO:0031391)
0.3 4.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.3 0.9 GO:0005827 polar microtubule(GO:0005827) tubulin complex(GO:0045298)
0.3 0.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.3 0.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 0.9 GO:0070985 TFIIK complex(GO:0070985)
0.3 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 1.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3 1.7 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.3 3.1 GO:0005791 rough endoplasmic reticulum(GO:0005791) rough endoplasmic reticulum membrane(GO:0030867)
0.3 1.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.3 1.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.3 1.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.3 1.8 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 2.2 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) multimeric ribonuclease P complex(GO:0030681)
0.2 1.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 3.0 GO:0016514 SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544)
0.2 1.5 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 1.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 0.7 GO:0033186 CAF-1 complex(GO:0033186)
0.2 0.9 GO:0033179 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2 0.9 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.2 1.6 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.2 0.7 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.2 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 1.3 GO:0005871 kinesin complex(GO:0005871)
0.2 1.7 GO:0031933 nuclear heterochromatin(GO:0005720) nuclear telomeric heterochromatin(GO:0005724) telomeric heterochromatin(GO:0031933)
0.2 2.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 0.4 GO:0030869 RENT complex(GO:0030869)
0.2 33.7 GO:0005933 cellular bud(GO:0005933)
0.2 0.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 0.9 GO:0035339 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
0.2 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.0 GO:0051233 spindle midzone(GO:0051233)
0.1 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.2 GO:0005688 U6 snRNP(GO:0005688)
0.1 2.0 GO:0034399 nuclear periphery(GO:0034399)
0.1 5.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.6 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.8 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 1.2 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 4.8 GO:0005811 lipid particle(GO:0005811)
0.1 5.4 GO:0030686 90S preribosome(GO:0030686)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.5 GO:0000444 MIS12/MIND type complex(GO:0000444) nuclear MIS12/MIND complex(GO:0000818)
0.1 0.4 GO:0005823 central plaque of spindle pole body(GO:0005823)
0.1 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.9 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.8 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 1.3 GO:0036464 ribonucleoprotein granule(GO:0035770) cytoplasmic ribonucleoprotein granule(GO:0036464)
0.1 13.0 GO:0005730 nucleolus(GO:0005730)
0.1 0.9 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 1.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.5 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.1 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.4 GO:0070772 PAS complex(GO:0070772)
0.1 1.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0000131 incipient cellular bud site(GO:0000131)
0.1 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.0 GO:0016586 RSC complex(GO:0016586)
0.1 0.2 GO:0042729 DASH complex(GO:0042729)
0.1 0.8 GO:0000786 nucleosome(GO:0000786)
0.1 0.3 GO:0033254 vacuolar transporter chaperone complex(GO:0033254)
0.1 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 2.6 GO:0044445 cytosolic part(GO:0044445)
0.1 0.2 GO:0097042 extrinsic component of fungal-type vacuolar membrane(GO:0097042)
0.1 1.8 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.2 GO:0097344 Rix1 complex(GO:0097344)
0.1 0.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 1.0 GO:0005844 polysome(GO:0005844)
0.1 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0000930 gamma-tubulin small complex, spindle pole body(GO:0000928) gamma-tubulin complex(GO:0000930) inner plaque of spindle pole body(GO:0005822) gamma-tubulin small complex(GO:0008275)
0.0 0.7 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.1 GO:0016587 Isw1 complex(GO:0016587)
0.0 0.1 GO:0070823 HDA1 complex(GO:0070823)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0034044 exomer complex(GO:0034044)
0.0 0.1 GO:0030892 mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990)
0.0 0.3 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0000178 nuclear exosome (RNase complex)(GO:0000176) exosome (RNase complex)(GO:0000178)
0.0 0.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0045254 mitochondrial pyruvate dehydrogenase complex(GO:0005967) pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.8 GO:0005815 microtubule organizing center(GO:0005815) spindle pole body(GO:0005816)
0.0 0.1 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 5.4 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 3.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.0 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271)
0.0 0.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.0 GO:0034448 EGO complex(GO:0034448)
0.0 0.6 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.7 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
2.3 13.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.9 5.6 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
1.7 7.0 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
1.6 6.2 GO:0016841 ammonia-lyase activity(GO:0016841)
1.3 5.1 GO:0015146 pentose transmembrane transporter activity(GO:0015146)
1.2 3.7 GO:0010521 telomerase inhibitor activity(GO:0010521)
1.2 3.5 GO:0001169 transcription factor activity, RNA polymerase I CORE element sequence-specific binding(GO:0001169) transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting(GO:0001187)
1.1 4.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.1 6.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
1.0 4.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.8 4.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.8 0.8 GO:0032451 demethylase activity(GO:0032451)
0.8 2.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.7 2.2 GO:0004100 chitin synthase activity(GO:0004100)
0.7 4.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.6 8.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.6 3.1 GO:0008443 phosphofructokinase activity(GO:0008443)
0.6 1.8 GO:0004805 trehalose-phosphatase activity(GO:0004805)
0.6 1.7 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.6 4.0 GO:0019201 nucleotide kinase activity(GO:0019201)
0.5 2.2 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.5 2.1 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.5 5.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.5 1.0 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.5 2.0 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.5 1.5 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.5 7.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.4 1.7 GO:0019206 nucleoside kinase activity(GO:0019206)
0.4 4.3 GO:0005216 ion channel activity(GO:0005216)
0.4 1.3 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.4 2.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.4 1.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 0.4 GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity(GO:0003825)
0.4 1.2 GO:0016872 intramolecular lyase activity(GO:0016872)
0.4 4.0 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.4 5.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 1.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.4 4.7 GO:0005199 structural constituent of cell wall(GO:0005199)
0.4 4.1 GO:0051213 dioxygenase activity(GO:0051213)
0.4 3.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.4 77.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 1.1 GO:0019901 protein kinase binding(GO:0019901)
0.4 3.6 GO:0001056 RNA polymerase III activity(GO:0001056)
0.3 1.4 GO:0030145 manganese ion binding(GO:0030145)
0.3 3.8 GO:0030295 protein kinase activator activity(GO:0030295)
0.3 1.6 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.3 1.6 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.3 1.9 GO:0004312 fatty acid synthase activity(GO:0004312)
0.3 6.3 GO:0030515 snoRNA binding(GO:0030515)
0.3 1.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.3 0.3 GO:0001082 transcription factor activity, RNA polymerase I transcription factor binding(GO:0001082)
0.3 4.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.3 1.2 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 0.9 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.3 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.3 6.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3 1.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.3 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 10.0 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.3 2.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.3 1.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.3 0.8 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.3 1.8 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.3 1.6 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 2.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 0.3 GO:1904680 peptide transmembrane transporter activity(GO:1904680)
0.2 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 2.2 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.2 1.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 2.8 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.2 0.9 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.2 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 14.0 GO:0003924 GTPase activity(GO:0003924)
0.2 2.2 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.2 0.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.2 0.6 GO:0070568 guanylyltransferase activity(GO:0070568)
0.2 0.4 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.2 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.2 2.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.2 1.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.2 0.8 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 0.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 3.9 GO:0008017 microtubule binding(GO:0008017)
0.2 1.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033) alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.2 0.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.2 0.6 GO:0016408 C-acyltransferase activity(GO:0016408)
0.2 0.5 GO:0016504 peptidase activator activity(GO:0016504)
0.2 1.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.2 1.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2 0.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 1.7 GO:0005516 calmodulin binding(GO:0005516)
0.2 0.8 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.2 0.3 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.2 1.0 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 0.5 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 0.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.2 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 0.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 1.8 GO:0042803 protein homodimerization activity(GO:0042803)
0.2 0.5 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.2 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078) signaling adaptor activity(GO:0035591)
0.1 4.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.7 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.4 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.1 0.7 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 2.5 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 0.8 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 0.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.4 GO:0019202 amino acid kinase activity(GO:0019202)
0.1 1.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 0.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.6 GO:0032934 steroid binding(GO:0005496) sterol binding(GO:0032934)
0.1 2.0 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 1.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.0 GO:0015631 tubulin binding(GO:0015631)
0.1 0.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 2.3 GO:0008170 N-methyltransferase activity(GO:0008170)
0.1 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.4 GO:0008252 nucleotidase activity(GO:0008252)
0.1 4.9 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.5 GO:0008312 7S RNA binding(GO:0008312)
0.1 2.0 GO:0016835 carbon-oxygen lyase activity(GO:0016835) hydro-lyase activity(GO:0016836)
0.1 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.9 GO:0051015 actin filament binding(GO:0051015)
0.1 0.3 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.1 0.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 2.6 GO:0030674 protein binding, bridging(GO:0030674)
0.1 0.2 GO:0043812 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.1 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.1 0.4 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 2.0 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.2 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.9 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 1.8 GO:0003779 actin binding(GO:0003779)
0.1 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 1.0 GO:0051087 chaperone binding(GO:0051087)
0.1 0.7 GO:0043495 protein anchor(GO:0043495)
0.1 0.7 GO:0019904 protein domain specific binding(GO:0019904)
0.1 0.3 GO:0042124 glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124)
0.1 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.9 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 0.2 GO:0004338 glucan exo-1,3-beta-glucosidase activity(GO:0004338)
0.1 0.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 0.1 GO:0015645 long-chain fatty acid-CoA ligase activity(GO:0004467) fatty acid ligase activity(GO:0015645)
0.1 0.2 GO:0016972 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) thiol oxidase activity(GO:0016972)
0.1 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 3.3 GO:0008289 lipid binding(GO:0008289)
0.0 0.3 GO:0001139 transcription factor activity, core RNA polymerase II recruiting(GO:0001139)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0008297 3'-5'-exodeoxyribonuclease activity(GO:0008296) single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.3 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 1.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 2.5 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.7 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139) ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483) transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 1.1 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.8 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0 0.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 3.7 GO:0003723 RNA binding(GO:0003723)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075) ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.0 GO:0015088 copper uptake transmembrane transporter activity(GO:0015088)
0.0 0.2 GO:0005525 GTP binding(GO:0005525) guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 1.8 PID ATR PATHWAY ATR signaling pathway
0.1 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 2.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.0 3.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.8 6.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.6 9.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.6 0.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.5 2.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.4 1.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.3 0.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.3 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.2 1.8 REACTOME SIGNALING BY GPCR Genes involved in Signaling by GPCR
0.1 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 0.8 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.9 REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS Genes involved in Metabolism of lipids and lipoproteins
0.0 0.5 REACTOME M G1 TRANSITION Genes involved in M/G1 Transition
0.0 0.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
0.0 0.2 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME TRANSCRIPTION Genes involved in Transcription
0.0 0.0 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.0 0.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane