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Results for YPR196W

Z-value: 0.72

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Transcription factors associated with YPR196W

Gene Symbol Gene ID Gene Info
S000006400 Putative maltose-responsive transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
YPR196W-0.203.2e-01Click!

Activity profile of YPR196W motif

Sorted Z-values of YPR196W motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YFR056C 2.82 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YHR095W 2.66 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YHR094C 2.44
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YGL035C 1.97
MIG1
Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase
YNL178W 1.90
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YFR054C 1.84 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDR278C 1.83 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YKR075C 1.80 Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YPL026C 1.68
SKS1
Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway
YGL033W 1.65
HOP2
Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair
YFR055W 1.49
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YJL106W 1.46
IME2
Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p
YJL214W 1.46
HXT8
Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose
YJL107C 1.39 Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi
YNL179C 1.39 Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; deletion in cyr1 mutant results in loss of stress resistance
YGR140W 1.35
CBF2
Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo
YLR308W 1.29
CDA2
Chitin deacetylase, together with Cda1p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall
YDR043C 1.28
NRG1
Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response
YNL180C 1.19
RHO5
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity
YNL065W 1.14
AQR1
Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids
YAR069C 1.07 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YHR093W 1.04
AHT1
Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; multicopy suppressor of glucose transport defects, likely due to the presence of an HXT4 regulatory element in the region
YLR154C 1.03
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YGR097W 1.02
ASK10
Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes
YJL215C 1.02 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YOR047C 1.02
STD1
Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p
YGL209W 0.99
MIG2
Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
YPR169W-A 0.99 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps two other dubious ORFs: YPR170C and YPR170W-B
YKL110C 0.98
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YDL241W 0.97 Putative protein of unknown function; YDL241W is not an essential gene
YKL063C 0.97 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
YML088W 0.95
UFO1
F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation
YNR062C 0.95 Putative membrane protein of unknown function
YKR099W 0.95
BAS1
Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways; also involved in regulation of meiotic recombination at specific genes
YGL177W 0.93 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOL045W 0.93
PSK2
One of two (see also PSK1) PAS domain containing S/T protein kinases; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation)
YOR306C 0.92
MCH5
Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport
YOR030W 0.92
DFG16
Probable multiple transmembrane protein, involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; required for accumulation of processed Rim101p
YMR290W-A 0.90 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase
YDR279W 0.85
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YBL063W 0.80
KIP1
Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p
YOR096W 0.80
RPS7A
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins
YGR242W 0.79 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C
YDL211C 0.79 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
YLR346C 0.77 Putative protein of unknown function found in mitochondria; expression is regulated by transcription factors involved in pleiotropic drug resistance, Pdr1p and Yrr1p; YLR346C is not an essential gene
YDR275W 0.76
BSC2
Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
YLR124W 0.75 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YKL062W 0.74
MSN4
Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
YLR108C 0.67 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YLR108C is not an esssential gene
YBR180W 0.66
DTR1
Putative dityrosine transporter, required for spore wall synthesis; expressed during sporulation; member of the major facilitator superfamily (DHA1 family) of multidrug resistance transporters
YOL156W 0.65
HXT11
Putative hexose transporter that is nearly identical to Hxt9p, has similarity to major facilitator superfamily (MFS) transporters and is involved in pleiotropic drug resistance
YAR070C 0.63 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YHR178W 0.62
STB5
Activator of multidrug resistance genes, forms a heterodimer with Pdr1p; contains a Zn(II)2Cys6 zinc finger domain that interacts with a PDRE (pleotropic drug resistance element) in vitro; binds Sin3p in a two-hybrid assay
YNR063W 0.60 Putative zinc-cluster protein of unknown function
YDL007C-A 0.60 Putative protein of unknown function
YJL162C 0.60
JJJ2
Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein
YNL235C 0.59 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF SIN4/YNL236W, a subunit of the mediator complex
YIL056W 0.58
VHR1
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations
YPL075W 0.58
GCR1
Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p
YGR034W 0.58
RPL26B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA
YJL105W 0.58
SET4
Protein of unknown function, contains a SET domain
YMR017W 0.57
SPO20
Meiosis-specific subunit of the t-SNARE complex, required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; SNAP-25 homolog
YOR050C 0.57 Hypothetical protein
YGL180W 0.56
ATG1
Protein serine/threonine kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for pre-autophagosome formation; during autophagy forms a complex with Atg13p and Atg17p
YDL022C-A 0.56 Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene DIA3; identified by fungal homology and RT-PCR
YKL109W 0.56
HAP4
Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex
YKR034W 0.55
DAL80
Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p
YAL018C 0.55 Putative protein of unknown function
YLR154W-C 0.53
TAR1
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand
YDR299W 0.52
BFR2
Essential protein possibly involved in secretion; multicopy suppressor of sensitivity to Brefeldin A
YJL112W 0.52
MDV1
Peripheral protein of the cytosolic face of the mitochondrial outer membrane, required for mitochondrial fission; interacts with Fis1p and with the dynamin-related GTPase Dnm1p; contains WD repeats
YOR063W 0.52
RPL3
Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
YAR053W 0.51 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YDL047W 0.50
SIT4
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
YPR119W 0.50
CLB2
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YBL085W 0.49
BOI1
Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
YDL048C 0.49
STP4
Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p
YBR292C 0.49 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YBR292C is not an essential gene
YOR029W 0.48 Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data
YLR013W 0.48
GAT3
Protein containing GATA family zinc finger motifs
YLL012W 0.48
YEH1
Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes
YOL100W 0.48
PKH2
Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh1p
YGL178W 0.48
MPT5
Member of the Puf family of RNA-binding proteins; binds to mRNAs encoding chromatin modifiers and spindle pole body components; involved in longevity, maintenance of cell wall integrity, and sensitivity to and recovery from pheromone arrest
YKL221W 0.47
MCH2
Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport
YOR130C 0.47
ORT1
Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome
YKR039W 0.47
GAP1
General amino acid permease; localization to the plasma membrane is regulated by nitrogen source
YPL141C 0.47 Putative protein kinase; similar to Kin4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL141C is not an essential gene
YGL158W 0.45
RCK1
Protein kinase involved in the response to oxidative stress; identified as suppressor of S. pombe cell cycle checkpoint mutations
YBR081C 0.45
SPT7
Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex
YGL201C 0.45
MCM6
Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
YOR274W 0.44
MOD5
Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; gene is nuclear and encodes two isozymic forms
YER169W 0.44
RPH1
JmjC domain-containing histone demethylase which can specifically demethylate H3K36 tri- and dimethyl modification states; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway
YBR034C 0.44
HMT1
Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; required for viability of npl3 mutants
YPL025C 0.44 Hypothetical protein
YOR388C 0.44
FDH1
NAD(+)-dependent formate dehydrogenase, may protect cells from exogenous formate
YCR092C 0.43
MSH3
Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability
YGR241C 0.43
YAP1802
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family
YPL062W 0.42 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation
YOR062C 0.41 Protein of unknown function; similar to YKR075Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YML053C 0.41 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; YML053C is not an essential gene
YDR259C 0.41
YAP6
Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance
YDR274C 0.40 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOR008C-A 0.40 Putative protein of unknown function, includes a potential transmembrane domain; deletion results in slightly lengthened telomeres
YNR072W 0.40
HXT17
Hexose transporter, up-regulated in media containing raffinose and galactose at pH 7.7 versus pH 4.7, repressed by high levels of glucose
YIL118W 0.40
RHO3
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
YMR037C 0.40
MSN2
Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
YGR287C 0.40 Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to alpha-D-glucosidase (maltase); authentic, non-tagged protein detected in purified mitochondria in high-throughput studies
YPR171W 0.40
BSP1
Adapter that links synaptojanins Inp52p and Inp53p to the cortical actin cytoskeleton
YMR290C 0.39
HAS1
ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles
YKR076W 0.39
ECM4
Omega class glutathione transferase; not essential; similar to Ygr154cp; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
YDR145W 0.39
TAF12
Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A
YNR001W-A 0.38 Dubious open reading frame unlikely to encode a functional protein; identified by homology
YKL166C 0.38
TPK3
cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk2p
YMR102C 0.38 Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene
YFL015W-A 0.38 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YBL037W 0.38
APL3
Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport
YIL119C 0.38
RPI1
Putative transcriptional regulator; overexpression suppresses the heat shock sensitivity of wild-type RAS2 overexpression and also suppresses the cell lysis defect of an mpk1 mutation
YIL057C 0.38 Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose
YEL007W 0.37 Putative protein with sequence similarity to S. pombe gti1+ (gluconate transport inducer 1)
YGR251W 0.37 Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene
YOR101W 0.37
RAS1
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes
YGR051C 0.36 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene
YCR093W 0.36
CDC39
Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor
YDR096W 0.36
GIS1
JmjC domain-containing histone demethylase; transcription factor involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1
YER137C 0.36 Putative protein of unknown function
YBR114W 0.36
RAD16
Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad7p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex
YOR058C 0.36
ASE1
Mitotic spindle midzone localized microtubule-associated protein (MAP) family member; required for spindle elongation and stabilization; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate
YMR124W 0.36 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; interacts with Crm1p in two-hybrid assay; YMR124W is not an essential gene
YBR238C 0.36 Mitochondrial membrane protein with similarity to Rmd9p; not required for respiratory growth but causes a synthetic respiratory defect in combination with rmd9 mutations; transcriptionally up-regulated by TOR; deletion increases life span
YMR100W 0.35
MUB1
Protein of unknown function, deletion causes multi-budding phenotype; has similarity to Aspergillus nidulans samB gene
YMR016C 0.35
SOK2
Nuclear protein that plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; negatively regulates pseudohyphal differentiation; homologous to several transcription factors
YDR095C 0.35 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YML091C 0.35
RPM2
Protein subunit of mitochondrial RNase P, has roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, and mitochondrial translation; distributed to mitochondria, cytoplasmic processing bodies, and the nucleus
YOR345C 0.35 Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene REV1; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2
YLR272C 0.34
YCS4
Non-SMC subunit of the condensin complex (Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p); required for establishment and maintenance of chromosome condensation, chromosome segregation, chromatin binding of condensin and silencing at the mating type locus
YDR170C 0.34
SEC7
Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles
YPL183C 0.33
RTT10
Cytoplasmic protein with a role in regulation of Ty1 transposition
YGR265W 0.33 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MES1/YGR264C, which encodes methionyl-tRNA synthetase
YOR355W 0.33
GDS1
Protein of unknown function, required for growth on glycerol as a carbon source; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YBR112C 0.33
CYC8
General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters
YHR006W 0.33
STP2
Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes
YDL187C 0.33 Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data
YML077W 0.32
BET5
Component of the TRAPP (transport protein particle) complex, which plays an essential role in the vesicular transport from endoplasmic reticulum to Golgi
YER131W 0.32
RPS26B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein
YER054C 0.32
GIP2
Putative regulatory subunit of the protein phosphatase Glc7p, involved in glycogen metabolism; contains a conserved motif (GVNK motif) that is also found in Gac1p, Pig1p, and Pig2p
YMR036C 0.32
MIH1
Protein tyrosine phosphatase involved in cell cycle control; regulates the phosphorylation state of Cdc28p; homolog of S. pombe cdc25
YER135C 0.32 Dubious open reading frame unlikely to encode a protein; YER135C is not an essential gene
YGL024W 0.32 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially/completely overlaps the verified ORF PGD1/YGL025C
YPL016W 0.32
SWI1
Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; can become prion [SWI+]
YIR019C 0.32
MUC1
GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)
YLR111W 0.32 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YLR255C 0.31 Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOR107W 0.31
RGS2
Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p
YNL118C 0.31
DCP2
Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; member of the Nudix hydrolase family
YJL194W 0.31
CDC6
Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p
YER164W 0.31
CHD1
Nucleosome remodeling factor that functions in regulation of transcription elongation; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SLIK complexes
YJR160C 0.31
MPH3
Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph2p; encoded in a subtelomeric position in a region likely to have undergone duplication
YER047C 0.31
SAP1
Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hybrid system
YLR263W 0.30
RED1
Protein component of the axial elements of the synaptonemal complex, involved in chromosome segregation during the first meiotic division; interacts with Hop1p; required for wild-type levels of Mek1p kinase activity
YIR028W 0.30
DAL4
Allantoin permease; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
YER059W 0.30
PCL6
Pho85p cyclin of the Pho80p subfamily; forms the major Glc8p kinase together with Pcl7p and Pho85p; involved in the control of glycogen storage by Pho85p; stabilized by Elongin C binding
YIL013C 0.30
PDR11
ATP-binding cassette (ABC) transporter, multidrug transporter involved in multiple drug resistance; mediates sterol uptake when sterol biosynthesis is compromisedregulated by Pdr1p; required for anaerobic growth
YER064C 0.30 Non-essential nuclear protein; null mutation has global effects on transcription
YBR106W 0.30
PHO88
Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations
YAL003W 0.29
EFB1
Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site
YKR032W 0.29 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YER037W 0.29
PHM8
Protein of unknown function, expression is induced by low phosphate levels and by inactivation of Pho85p
YHR212W-A 0.29 Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
YMR011W 0.29
HXT2
High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose
YBR007C 0.29
DSF2
Deletion suppressor of mpt5 mutation
YOL051W 0.29
GAL11
Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors
YLR448W 0.29
RPL6B
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA
YER062C 0.29
HOR2
One of two redundant DL-glycerol-3-phosphatases (RHR2/GPP1 encodes the other) involved in glycerol biosynthesis; induced in response to hyperosmotic stress and oxidative stress, and during the diauxic transition
YHR021C 0.28
RPS27B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Ap and has similarity to rat S27 ribosomal protein
YKL064W 0.28
MNR2
Putative magnesium transporter; has similarity to Alr1p and Alr2p, which mediate influx of Mg2+ and other divalent cations
YER097W 0.28 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YJR092W 0.28
BUD4
Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate
YFL034C-A 0.28
RPL22B
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Ap and to rat L22 ribosomal protein
YDR028C 0.28
REG1
Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-repressible genes
YPL143W 0.28
RPL33A
N-terminally acetylated ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Bp and has similarity to rat L35a; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable
YLR431C 0.28
ATG23
Peripheral membrane protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway; cycles between the pre-autophagosome (PAS) and non-PAS locations; forms a complex with Atg9p and Atg27p
YDL023C 0.28 Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance
YGR264C 0.28
MES1
Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs
YDR029W 0.28 Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data
YNL273W 0.28
TOF1
Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase
YDR441C 0.28
APT2
Apparent pseudogene, not transcribed or translated under normal conditions; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity
YLR191W 0.27
PEX13
Integral peroxisomal membrane required for the translocation of peroxisomal matrix proteins, interacts with the PTS1 signal recognition factor Pex5p and the PTS2 signal recognition factor Pex7p, forms a complex with Pex14p and Pex17p
YDR499W 0.27
LCD1
Essential protein required for the DNA integrity checkpoint pathways; interacts physically with Mec1p; putative homolog of S. pombe Rad26 and human ATRIP
YMR136W 0.27
GAT2
Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucine
YIL144W 0.27
TID3
Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, kinetochore assembly and clustering
YEL061C 0.27
CIN8
Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation
YJR128W 0.27 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RSF2
YMR135W-A 0.26 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YBR300C 0.26 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YBR301W; YBR300C is not an essential gene
YHR046C 0.26
INM1
Inositol monophosphatase, involved in biosynthesis of inositol and in phosphoinositide second messenger signaling; INM1 expression increases in the presence of inositol and decreases upon exposure to antibipolar drugs lithium and valproate
YLR223C 0.26
IFH1
Essential protein with a highly acidic N-terminal domain; IFH1 exhibits genetic interactions with FHL1, overexpression interferes with silencing at telomeres and HM loci; potential Cdc28p substrate
YDR442W 0.26 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDL122W 0.26
UBP1
Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; cleaves at the C terminus of ubiquitin fusions irrespective of their size; capable of cleaving polyubiquitin chains
YNL221C 0.26
POP1
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in RNase P
YPL219W 0.26
PCL8
Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk) to phosphorylate and regulate glycogen synthase, also activates Pho85p for Glc8p phosphorylation

Network of associatons between targets according to the STRING database.

First level regulatory network of YPR196W

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:1900436 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
0.5 1.5 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.5 1.4 GO:1900460 negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter(GO:1900460)
0.4 1.3 GO:0061422 positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH(GO:0061422)
0.4 1.5 GO:0000092 mitotic anaphase B(GO:0000092)
0.3 1.0 GO:0046495 nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637)
0.3 1.6 GO:1901072 aminoglycan catabolic process(GO:0006026) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.3 1.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 1.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.2 1.1 GO:0071406 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
0.2 0.8 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214) histone demethylation(GO:0016577) demethylation(GO:0070988)
0.2 0.6 GO:0072363 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
0.2 1.0 GO:0015793 glycerol transport(GO:0015793)
0.2 1.0 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.2 0.6 GO:0042126 nitrate metabolic process(GO:0042126) nitrate assimilation(GO:0042128)
0.2 1.1 GO:0032973 amino acid export(GO:0032973)
0.2 1.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 1.8 GO:0015758 glucose transport(GO:0015758)
0.2 1.0 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151)
0.2 1.4 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.1 0.4 GO:0018195 peptidyl-arginine modification(GO:0018195) peptidyl-arginine methylation(GO:0018216)
0.1 0.4 GO:0035953 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
0.1 1.0 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
0.1 0.7 GO:0007188 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger(GO:0007187) adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.1 2.3 GO:0007129 synapsis(GO:0007129)
0.1 0.1 GO:0006110 regulation of glycolytic process(GO:0006110)
0.1 0.8 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.3 GO:0044109 cellular alcohol catabolic process(GO:0044109)
0.1 0.3 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1 0.3 GO:0001178 regulation of transcriptional start site selection at RNA polymerase II promoter(GO:0001178)
0.1 0.5 GO:0032233 regulation of actin filament bundle assembly(GO:0032231) positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.3 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 0.4 GO:0014070 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
0.1 0.8 GO:0051180 vitamin transport(GO:0051180)
0.1 0.3 GO:0060963 positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter(GO:0060963)
0.1 0.2 GO:0071482 cellular response to radiation(GO:0071478) cellular response to light stimulus(GO:0071482)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:0008334 histone mRNA metabolic process(GO:0008334) histone mRNA catabolic process(GO:0071044)
0.1 0.4 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glycogen metabolic process(GO:0070873)
0.1 0.2 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111) regulation of microtubule depolymerization(GO:0031114)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.4 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 2.4 GO:0051445 regulation of meiotic nuclear division(GO:0040020) regulation of meiotic cell cycle(GO:0051445)
0.1 0.1 GO:2000002 regulation of cell cycle checkpoint(GO:1901976) negative regulation of cell cycle checkpoint(GO:1901977) regulation of DNA damage checkpoint(GO:2000001) negative regulation of DNA damage checkpoint(GO:2000002) negative regulation of response to DNA damage stimulus(GO:2001021)
0.1 0.4 GO:0000735 removal of nonhomologous ends(GO:0000735)
0.1 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957)
0.1 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.1 GO:0051303 meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.1 0.3 GO:0097271 protein localization to bud neck(GO:0097271)
0.1 0.3 GO:0000279 mitotic M phase(GO:0000087) M phase(GO:0000279)
0.1 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 1.1 GO:0000045 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.1 0.3 GO:0016036 cellular response to phosphate starvation(GO:0016036)
0.1 0.7 GO:0031070 intronic snoRNA processing(GO:0031070) intronic box C/D snoRNA processing(GO:0034965)
0.1 0.1 GO:0097306 positive regulation of transcription from RNA polymerase II promoter in response to ethanol(GO:0061410) cellular response to ethanol(GO:0071361) cellular response to alcohol(GO:0097306)
0.1 0.1 GO:0006343 establishment of chromatin silencing(GO:0006343)
0.1 0.6 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
0.1 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160) osmosensory signaling via phosphorelay pathway(GO:0007234)
0.1 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900) tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.1 1.4 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 0.2 GO:0071474 cellular hyperosmotic response(GO:0071474)
0.1 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.3 GO:0043007 maintenance of rDNA(GO:0043007)
0.1 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.1 0.1 GO:0006068 ethanol catabolic process(GO:0006068) primary alcohol catabolic process(GO:0034310)
0.1 0.1 GO:0061416 regulation of transcription from RNA polymerase II promoter in response to salt stress(GO:0061416)
0.1 0.3 GO:0048478 replication fork protection(GO:0048478)
0.1 0.2 GO:0015883 FAD transport(GO:0015883)
0.1 0.5 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.2 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 0.2 GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461)
0.1 0.2 GO:0048313 Golgi inheritance(GO:0048313)
0.1 0.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.6 GO:0006817 phosphate ion transport(GO:0006817)
0.1 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 1.1 GO:0042594 response to starvation(GO:0042594)
0.1 1.3 GO:0002098 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.1 7.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.0 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414) histone H3-K36 methylation(GO:0010452)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0051222 positive regulation of protein transport(GO:0051222) positive regulation of establishment of protein localization(GO:1904951)
0.0 0.2 GO:0072479 cellular response to biotic stimulus(GO:0071216) response to cell cycle checkpoint signaling(GO:0072396) response to mitotic cell cycle checkpoint signaling(GO:0072414) response to spindle checkpoint signaling(GO:0072417) response to mitotic spindle checkpoint signaling(GO:0072476) response to mitotic cell cycle spindle assembly checkpoint signaling(GO:0072479) response to spindle assembly checkpoint signaling(GO:0072485) negative regulation of protein import into nucleus during spindle assembly checkpoint(GO:1901925)
0.0 0.2 GO:0007119 budding cell isotropic bud growth(GO:0007119)
0.0 0.2 GO:0034503 protein localization to nucleolar rDNA repeats(GO:0034503)
0.0 0.1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.0 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 0.7 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.1 GO:0032186 cellular bud neck septin ring organization(GO:0032186)
0.0 0.2 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.0 0.2 GO:0007534 gene conversion at mating-type locus(GO:0007534)
0.0 0.2 GO:0001015 snoRNA transcription from an RNA polymerase II promoter(GO:0001015)
0.0 0.2 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.1 GO:0046320 regulation of fatty acid beta-oxidation(GO:0031998) positive regulation of fatty acid beta-oxidation(GO:0032000) regulation of fatty acid oxidation(GO:0046320) positive regulation of fatty acid oxidation(GO:0046321) regulation of lipid catabolic process(GO:0050994) positive regulation of lipid catabolic process(GO:0050996)
0.0 0.2 GO:0007535 donor selection(GO:0007535)
0.0 0.1 GO:1902750 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.1 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.1 GO:0031135 negative regulation of conjugation(GO:0031135) negative regulation of conjugation with cellular fusion(GO:0031138) negative regulation of multi-organism process(GO:0043901)
0.0 0.1 GO:0046136 regulation of vitamin metabolic process(GO:0030656) positive regulation of vitamin metabolic process(GO:0046136) regulation of thiamine biosynthetic process(GO:0070623) positive regulation of thiamine biosynthetic process(GO:0090180)
0.0 0.1 GO:0008272 sulfate transport(GO:0008272)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0016233 telomere capping(GO:0016233)
0.0 0.1 GO:0000949 aromatic amino acid family catabolic process to alcohol via Ehrlich pathway(GO:0000949)
0.0 0.0 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
0.0 0.5 GO:0031321 ascospore-type prospore assembly(GO:0031321)
0.0 0.1 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0070649 parallel actin filament bundle assembly(GO:0030046) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473)
0.0 0.0 GO:0010962 regulation of glucan biosynthetic process(GO:0010962) regulation of polysaccharide biosynthetic process(GO:0032885)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0019218 regulation of steroid metabolic process(GO:0019218) regulation of ergosterol biosynthetic process(GO:0032443) regulation of steroid biosynthetic process(GO:0050810)
0.0 0.3 GO:0030473 establishment of localization by movement along microtubule(GO:0010970) nuclear migration along microtubule(GO:0030473) organelle transport along microtubule(GO:0072384)
0.0 0.1 GO:0006075 (1->3)-beta-D-glucan biosynthetic process(GO:0006075)
0.0 0.4 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress(GO:0036003)
0.0 0.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0030474 spindle pole body duplication(GO:0030474)
0.0 0.2 GO:0031578 mitotic spindle orientation checkpoint(GO:0031578)
0.0 0.2 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 0.2 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.5 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:2001023 cellular response to drug(GO:0035690) regulation of response to drug(GO:2001023) positive regulation of response to drug(GO:2001025) regulation of cellular response to drug(GO:2001038) positive regulation of cellular response to drug(GO:2001040)
0.0 0.1 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.0 0.5 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0031032 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin structure organization(GO:0031032) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of mitotic spindle localization(GO:0040001) establishment of spindle orientation(GO:0051294)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.8 GO:0016485 protein processing(GO:0016485)
0.0 1.2 GO:0016573 histone acetylation(GO:0016573)
0.0 0.1 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.2 GO:0000921 septin ring assembly(GO:0000921)
0.0 0.1 GO:0043200 response to amino acid(GO:0043200)
0.0 0.2 GO:0045003 double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.2 GO:0055070 cellular copper ion homeostasis(GO:0006878) copper ion homeostasis(GO:0055070)
0.0 0.1 GO:0043419 urea catabolic process(GO:0043419)
0.0 0.4 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.0 GO:0051322 anaphase(GO:0051322)
0.0 0.7 GO:0006200 obsolete ATP catabolic process(GO:0006200)
0.0 0.5 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.1 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.8 GO:0070591 ascospore wall assembly(GO:0030476) spore wall assembly(GO:0042244) spore wall biogenesis(GO:0070590) ascospore wall biogenesis(GO:0070591) fungal-type cell wall assembly(GO:0071940)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0042173 regulation of sporulation resulting in formation of a cellular spore(GO:0042173)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.0 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.1 GO:0001402 signal transduction involved in filamentous growth(GO:0001402)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.0 GO:0042710 biofilm formation(GO:0042710)
0.0 0.2 GO:0042886 amide transport(GO:0042886)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0051666 actin cortical patch localization(GO:0051666)
0.0 0.0 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0034201 response to lipid(GO:0033993) response to oleic acid(GO:0034201) response to fatty acid(GO:0070542) cellular response to lipid(GO:0071396) cellular response to fatty acid(GO:0071398) cellular response to oleic acid(GO:0071400)
0.0 0.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.1 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.0 GO:0009202 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.0 0.1 GO:0030007 cellular potassium ion homeostasis(GO:0030007) potassium ion homeostasis(GO:0055075)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950) establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.1 GO:0006797 polyphosphate metabolic process(GO:0006797)
0.0 0.9 GO:0008033 tRNA processing(GO:0008033)
0.0 0.1 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.3 GO:0009304 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0019932 second-messenger-mediated signaling(GO:0019932)
0.0 0.2 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.0 GO:0031047 gene silencing involved in chronological cell aging(GO:0010978) gene silencing by RNA(GO:0031047)
0.0 0.1 GO:0072668 obsolete tubulin complex biogenesis(GO:0072668)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.0 GO:0001315 age-dependent response to reactive oxygen species(GO:0001315)
0.0 0.1 GO:0006284 base-excision repair(GO:0006284)
0.0 0.0 GO:0051601 exocyst localization(GO:0051601)
0.0 0.0 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.4 GO:0051302 regulation of cell division(GO:0051302)
0.0 0.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0009099 valine biosynthetic process(GO:0009099)
0.0 0.2 GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay(GO:0070481)
0.0 0.1 GO:0007323 peptide pheromone maturation(GO:0007323)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0043270 positive regulation of ion transport(GO:0043270)
0.0 0.0 GO:0090342 regulation of cell aging(GO:0090342) regulation of replicative cell aging(GO:1900062)
0.0 0.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.0 GO:0070478 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay(GO:0070478)
0.0 0.1 GO:0000372 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.0 0.0 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0007532 regulation of mating-type specific transcription, DNA-templated(GO:0007532)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.0 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.0 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.0 GO:0090522 vesicle tethering involved in exocytosis(GO:0090522)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106) lipoate biosynthetic process(GO:0009107)
0.0 0.8 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.0 GO:0032262 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.0 0.1 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0006768 biotin metabolic process(GO:0006768) biotin biosynthetic process(GO:0009102)
0.0 0.0 GO:0000433 negative regulation of transcription from RNA polymerase II promoter by glucose(GO:0000433) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound biosynthetic process(GO:0042559)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 2.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.3 1.4 GO:0031518 CBF3 complex(GO:0031518)
0.2 1.2 GO:0005871 kinesin complex(GO:0005871)
0.2 0.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 0.9 GO:0044426 cell wall part(GO:0044426) external encapsulating structure part(GO:0044462)
0.2 1.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.4 GO:0000113 nucleotide-excision repair factor 4 complex(GO:0000113)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.1 GO:0000112 nucleotide-excision repair factor 3 complex(GO:0000112)
0.1 0.3 GO:0030874 nucleolar chromatin(GO:0030874)
0.1 1.0 GO:0030677 ribonuclease P complex(GO:0030677)
0.1 0.5 GO:0032545 CURI complex(GO:0032545)
0.1 0.4 GO:0030669 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128) endocytic vesicle(GO:0030139) endocytic vesicle membrane(GO:0030666) clathrin-coated endocytic vesicle membrane(GO:0030669) clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.5 GO:0005771 multivesicular body(GO:0005771)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.6 GO:0051233 spindle midzone(GO:0051233)
0.1 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.2 GO:0032177 split septin rings(GO:0032176) cellular bud neck split septin rings(GO:0032177)
0.1 1.2 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.5 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 0.4 GO:0000796 condensin complex(GO:0000796) nuclear condensin complex(GO:0000799)
0.1 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 3.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.3 GO:0070775 NuA3 histone acetyltransferase complex(GO:0033100) H3 histone acetyltransferase complex(GO:0070775)
0.1 4.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.3 GO:0031499 TRAMP complex(GO:0031499)
0.1 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.4 GO:0005628 prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764)
0.0 0.2 GO:0005823 central plaque of spindle pole body(GO:0005823)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.1 GO:0030880 DNA-directed RNA polymerase complex(GO:0000428) RNA polymerase complex(GO:0030880)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0008278 nuclear cohesin complex(GO:0000798) cohesin complex(GO:0008278)
0.0 0.1 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.2 GO:0070772 PAS complex(GO:0070772)
0.0 1.8 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0097042 extrinsic component of fungal-type vacuolar membrane(GO:0097042)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0072380 ER membrane insertion complex(GO:0072379) TRC complex(GO:0072380)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0000144 cellular bud neck septin ring(GO:0000144)
0.0 0.4 GO:0000142 cellular bud neck contractile ring(GO:0000142)
0.0 0.1 GO:0097344 Rix1 complex(GO:0097344)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.9 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.5 GO:0030118 clathrin coat(GO:0030118)
0.0 0.1 GO:0033254 vacuolar transporter chaperone complex(GO:0033254)
0.0 0.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.0 GO:0000148 1,3-beta-D-glucan synthase complex(GO:0000148)
0.0 0.1 GO:0000417 HIR complex(GO:0000417)
0.0 0.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.0 GO:0033597 mitotic checkpoint complex(GO:0033597)
0.0 1.6 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0033101 cellular bud membrane(GO:0033101)
0.0 0.2 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.5 GO:0005935 cellular bud neck(GO:0005935)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.0 GO:0005825 half bridge of spindle pole body(GO:0005825)
0.0 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.2 GO:0098552 side of membrane(GO:0098552) cytoplasmic side of membrane(GO:0098562)
0.0 0.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0016587 Isw1 complex(GO:0016587)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.0 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.0 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0000136 alpha-1,6-mannosyltransferase complex(GO:0000136)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.0 GO:0070823 HDA1 complex(GO:0070823)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.2 GO:0016586 RSC complex(GO:0016586)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.0 GO:0032116 SMC loading complex(GO:0032116)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0035361 Cul8-RING ubiquitin ligase complex(GO:0035361)
0.0 0.0 GO:0000814 ESCRT II complex(GO:0000814)
0.0 12.8 GO:0005634 nucleus(GO:0005634)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0005354 galactose transmembrane transporter activity(GO:0005354)
0.5 1.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 2.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.3 5.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 0.9 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.2 1.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.4 GO:0000403 Y-form DNA binding(GO:0000403)
0.2 0.9 GO:0051183 vitamin transporter activity(GO:0051183)
0.2 0.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.4 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.4 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.3 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 0.4 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.1 1.9 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.9 GO:0019901 protein kinase binding(GO:0019901)
0.1 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.2 GO:0003951 NAD+ kinase activity(GO:0003951) NADH kinase activity(GO:0042736)
0.1 0.5 GO:0042887 amide transmembrane transporter activity(GO:0042887)
0.1 0.5 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 1.4 GO:0019213 deacetylase activity(GO:0019213)
0.1 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.3 GO:0008252 nucleotidase activity(GO:0008252)
0.1 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.4 GO:0015038 peptide disulfide oxidoreductase activity(GO:0015037) glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.1 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.1 0.2 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.1 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.3 GO:0004338 glucan exo-1,3-beta-glucosidase activity(GO:0004338)
0.1 0.2 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 1.3 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.2 GO:0008902 hydroxymethylpyrimidine kinase activity(GO:0008902) phosphomethylpyrimidine kinase activity(GO:0008972)
0.1 0.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 5.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 2.1 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 3.0 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 1.1 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 1.5 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.3 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 7.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0005186 mating pheromone activity(GO:0000772) pheromone activity(GO:0005186)
0.0 0.1 GO:0015116 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.0 1.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0090484 drug transporter activity(GO:0090484)
0.0 0.1 GO:0005034 osmosensor activity(GO:0005034)
0.0 0.2 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.3 GO:0019001 GTP binding(GO:0005525) guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561)
0.0 0.3 GO:0016896 exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.1 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.1 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.0 GO:0019842 vitamin binding(GO:0019842)
0.0 0.1 GO:0008251 adenosine deaminase activity(GO:0004000) tRNA-specific adenosine deaminase activity(GO:0008251)
0.0 0.1 GO:0070717 poly(A) binding(GO:0008143) poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.9 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.0 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.0 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.0 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.0 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 1.0 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.3 GO:0061733 histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 0.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.0 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.0 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.1 GO:0018456 aryl-alcohol dehydrogenase (NAD+) activity(GO:0018456)
0.0 0.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0034212 peptide alpha-N-acetyltransferase activity(GO:0004596) peptide N-acetyltransferase activity(GO:0034212)
0.0 0.1 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.0 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 0.1 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 0.4 PID MYC PATHWAY C-MYC pathway
0.1 0.4 PID E2F PATHWAY E2F transcription factor network
0.1 0.2 PID ATM PATHWAY ATM pathway
0.0 0.5 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 PID SHP2 PATHWAY SHP2 signaling
0.0 0.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 18.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.0 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 2.3 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.2 0.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.3 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.1 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 0.6 REACTOME RNA POL II TRANSCRIPTION Genes involved in RNA Polymerase II Transcription
0.0 0.2 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
0.0 0.1 REACTOME SIGNALLING TO ERKS Genes involved in Signalling to ERKs
0.0 0.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.1 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 18.6 REACTOME GLYCOSAMINOGLYCAN METABOLISM Genes involved in Glycosaminoglycan metabolism
0.0 0.1 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.0 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance