Results for YPR022C
Z-value: 2.04
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Transcription factors associated with YPR022C
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| S000006226 | Putative transcription factor, as suggested by computational analysis |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YHR217C Show fit | 34.08 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; located in the telomeric region TEL08R. |
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| YFL063W Show fit | 23.12 |
Dubious open reading frame, based on available experimental and comparative sequence data |
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| YKL217W Show fit | 22.80 |
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose |
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| YHR218W Show fit | 22.00 |
Helicase-like protein encoded within the telomeric Y' element |
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| YFL064C Show fit | 18.78 |
Putative protein of unknown function |
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| YBR117C Show fit | 18.10 |
Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids |
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| YFL052W Show fit | 17.23 |
Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity |
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| YGR067C Show fit | 14.82 |
Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p |
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| YDR536W Show fit | 14.77 |
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock |
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| YNL337W Show fit | 14.75 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
Network of associatons between targets according to the STRING database.
First level regulatory network of YPR022C
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 32.2 | GO:0006094 | gluconeogenesis(GO:0006094) |
| 1.5 | 31.9 | GO:0008645 | hexose transport(GO:0008645) monosaccharide transport(GO:0015749) |
| 0.5 | 26.5 | GO:0009060 | aerobic respiration(GO:0009060) |
| 6.3 | 25.3 | GO:0006848 | pyruvate transport(GO:0006848) |
| 1.4 | 23.1 | GO:0005978 | glycogen biosynthetic process(GO:0005978) |
| 2.2 | 21.9 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
| 4.1 | 20.7 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 1.4 | 19.8 | GO:0019682 | pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682) |
| 2.3 | 15.8 | GO:0000023 | maltose metabolic process(GO:0000023) |
| 1.6 | 14.7 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 83.8 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.2 | 28.5 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.2 | 27.5 | GO:0000323 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
| 0.9 | 24.7 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.8 | 14.0 | GO:0031307 | intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307) |
| 1.6 | 13.1 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.2 | 9.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.7 | 8.9 | GO:0045259 | mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259) |
| 0.9 | 7.5 | GO:0042597 | periplasmic space(GO:0042597) |
| 1.8 | 7.1 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.8 | 44.0 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 3.7 | 22.4 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
| 2.9 | 17.5 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
| 1.5 | 17.5 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 1.2 | 17.3 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 1.2 | 16.7 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578) |
| 3.7 | 14.8 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 14.6 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 2.9 | 14.3 | GO:0015294 | solute:cation symporter activity(GO:0015294) |
| 1.1 | 14.3 | GO:0044389 | ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 247.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 5.0 | 15.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 1.1 | 4.4 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.5 | 4.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.4 | 1.8 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.5 | 1.6 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.4 | 0.7 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.2 | 0.5 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.2 | 0.4 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.1 | 0.2 | PID NOTCH PATHWAY | Notch signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 240.2 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 2.9 | 26.4 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 1.4 | 4.2 | REACTOME PI3K EVENTS IN ERBB2 SIGNALING | Genes involved in PI3K events in ERBB2 signaling |
| 0.8 | 2.3 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 1.1 | 2.2 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 1.0 | 2.0 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.5 | 1.5 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.2 | 1.2 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 0.4 | 1.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.3 | 0.9 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |