Results for YML081W
Z-value: 0.47
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Transcription factors associated with YML081W
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TDA9
|
S000004546 | DNA-binding protein, putative transcription factor |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YFR055W Show fit | 8.50 |
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner |
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| YFR056C Show fit | 7.81 |
Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W |
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| YKR075C Show fit | 4.50 |
Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS |
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| YGR242W Show fit | 4.21 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C |
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| YDR041W Show fit | 4.02 |
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins |
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| YOR101W Show fit | 3.81 |
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes |
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| YDR033W Show fit | 3.78 |
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p |
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| YMR290W-A Show fit | 3.51 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase |
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| YGR241C Show fit | 3.45 |
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family |
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| YMR290C Show fit | 3.45 |
ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles |
Network of associatons between targets according to the STRING database.
First level regulatory network of YML081W
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 14.4 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 2.8 | 8.5 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.1 | 7.1 | GO:0032543 | mitochondrial translation(GO:0032543) |
| 0.7 | 6.2 | GO:0006814 | sodium ion transport(GO:0006814) |
| 0.0 | 5.5 | GO:0006364 | rRNA processing(GO:0006364) |
| 0.6 | 4.3 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 1.3 | 3.8 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
| 0.5 | 3.8 | GO:0010696 | positive regulation of spindle pole body separation(GO:0010696) |
| 0.4 | 3.6 | GO:0000947 | amino acid catabolic process to alcohol via Ehrlich pathway(GO:0000947) |
| 0.7 | 2.7 | GO:1900436 | filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 15.6 | GO:0005933 | cellular bud(GO:0005933) |
| 0.1 | 11.1 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.2 | 5.4 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.1 | 5.3 | GO:0015935 | small ribosomal subunit(GO:0015935) |
| 0.1 | 4.4 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 4.4 | GO:0098852 | fungal-type vacuole membrane(GO:0000329) lytic vacuole membrane(GO:0098852) |
| 1.4 | 4.2 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.3 | 3.8 | GO:0030118 | clathrin coat(GO:0030118) |
| 0.1 | 3.5 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.1 | 3.4 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 22.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 1.4 | 8.4 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.5 | 5.6 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.1 | 5.1 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.7 | 4.3 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 1.0 | 4.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.0 | 4.2 | GO:0003723 | RNA binding(GO:0003723) |
| 0.1 | 4.0 | GO:0008186 | RNA-dependent ATPase activity(GO:0008186) |
| 0.2 | 3.8 | GO:0019901 | protein kinase binding(GO:0019901) |
| 0.5 | 3.6 | GO:0015081 | sodium ion transmembrane transporter activity(GO:0015081) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.4 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.2 | 0.8 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 0.3 | PID FOXO PATHWAY | FoxO family signaling |
| 0.1 | 0.3 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.1 | 0.2 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 0.2 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.0 | 0.2 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.1 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 0.1 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.1 | PID ATR PATHWAY | ATR signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.5 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.2 | 1.2 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.3 | 1.0 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.3 | 0.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.3 | 0.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.2 | 0.9 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.2 | 0.8 | REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
| 0.2 | 0.7 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 0.6 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.2 | 0.5 | REACTOME TRIF MEDIATED TLR3 SIGNALING | Genes involved in TRIF mediated TLR3 signaling |