Results for YLL054C
Z-value: 0.84
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Transcription factors associated with YLL054C
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| S000003977 | Putative protein of unknown function with similarity to Pip2p |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YLR154W-A Show fit | 7.60 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YLR154W-B Show fit | 7.34 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YLR154C Show fit | 6.52 |
Ribonuclease H2 subunit, required for RNase H2 activity |
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| YLR349W Show fit | 5.34 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified ORF DIC1/YLR348C |
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| YJR094W-A Show fit | 5.07 |
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein |
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| YLR348C Show fit | 5.00 |
Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix |
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| YLL045C Show fit | 4.78 |
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits |
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| YLR154W-C Show fit | 4.53 |
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand |
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| YPL250W-A Show fit | 4.38 |
Identified by fungal homology and RT-PCR |
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| YKR092C Show fit | 4.11 |
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140 |
Network of associatons between targets according to the STRING database.
First level regulatory network of YLL054C
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 44.2 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.6 | 9.5 | GO:0051029 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
| 1.0 | 6.8 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 1.0 | 6.7 | GO:0006835 | dicarboxylic acid transport(GO:0006835) |
| 1.2 | 4.9 | GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461) |
| 0.5 | 4.6 | GO:0006817 | phosphate ion transport(GO:0006817) |
| 0.2 | 4.0 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 1.3 | 3.8 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
| 0.2 | 3.7 | GO:0006469 | negative regulation of protein kinase activity(GO:0006469) |
| 0.0 | 3.7 | GO:0006913 | nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 39.5 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.4 | 24.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 8.5 | GO:0005730 | nucleolus(GO:0005730) |
| 2.2 | 6.5 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.2 | 4.4 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 3.9 | GO:0005933 | cellular bud(GO:0005933) |
| 0.0 | 2.2 | GO:0005840 | ribosome(GO:0005840) |
| 0.3 | 1.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.2 | 1.5 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.1 | 1.4 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 60.0 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 8.4 | GO:0003924 | GTPase activity(GO:0003924) |
| 1.6 | 6.5 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.7 | 6.5 | GO:0005310 | dicarboxylic acid transmembrane transporter activity(GO:0005310) |
| 0.1 | 4.0 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 1.3 | 3.8 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.6 | 3.7 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.6 | 3.6 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
| 0.2 | 3.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.6 | 3.2 | GO:0070546 | L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.5 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 0.9 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 0.4 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.1 | 0.3 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 0.2 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 0.2 | PID MYC PATHWAY | C-MYC pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.7 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.6 | 4.5 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.8 | 2.5 | REACTOME SIGNALING BY INSULIN RECEPTOR | Genes involved in Signaling by Insulin receptor |
| 0.5 | 1.6 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.2 | 1.5 | REACTOME DEADENYLATION DEPENDENT MRNA DECAY | Genes involved in Deadenylation-dependent mRNA decay |
| 0.2 | 1.1 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.5 | 0.9 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.1 | 0.4 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.1 | 0.4 | REACTOME GPCR LIGAND BINDING | Genes involved in GPCR ligand binding |
| 0.2 | 0.3 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |