Results for YBR239C
Z-value: 1.31
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Transcription factors associated with YBR239C
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ERT1
|
S000000443 | Transcriptional regulator of nonfermentable carbon utilization |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YFR055W Show fit | 13.76 |
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner |
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| YGR108W Show fit | 12.52 |
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome |
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| YFR056C Show fit | 12.00 |
Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W |
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| YGR052W Show fit | 9.44 |
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation |
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| YER131W Show fit | 8.33 |
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein |
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| YLR154C Show fit | 8.32 |
Ribonuclease H2 subunit, required for RNase H2 activity |
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| YLR154W-B Show fit | 7.16 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YGR050C Show fit | 6.89 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YLR154W-A Show fit | 6.74 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YNR001W-A Show fit | 6.34 |
Dubious open reading frame unlikely to encode a functional protein; identified by homology |
Network of associatons between targets according to the STRING database.
First level regulatory network of YBR239C
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 21.2 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 1.1 | 20.0 | GO:0051029 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
| 2.0 | 14.1 | GO:0010696 | positive regulation of spindle pole body separation(GO:0010696) |
| 4.6 | 13.8 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 1.5 | 10.5 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 1.0 | 8.7 | GO:0000947 | amino acid catabolic process to alcohol via Ehrlich pathway(GO:0000947) |
| 0.3 | 7.3 | GO:0097384 | ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384) |
| 1.0 | 6.9 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501) |
| 0.3 | 6.8 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.5 | 6.7 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 24.9 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.3 | 22.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.9 | 15.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 3.5 | 10.5 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.1 | 8.5 | GO:0005933 | cellular bud(GO:0005933) |
| 0.8 | 7.6 | GO:0000144 | cellular bud neck septin ring(GO:0000144) |
| 0.4 | 5.8 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 5.7 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 1.7 | 5.1 | GO:0030428 | cell septum(GO:0030428) |
| 0.0 | 5.0 | GO:0005730 | nucleolus(GO:0005730) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 43.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.7 | 17.2 | GO:0019901 | protein kinase binding(GO:0019901) |
| 2.0 | 11.7 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 2.6 | 10.5 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.3 | 10.0 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
| 1.5 | 9.0 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.8 | 9.0 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
| 0.3 | 7.4 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 1.7 | 6.8 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
| 0.4 | 6.6 | GO:0003746 | translation elongation factor activity(GO:0003746) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.1 | 0.5 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.2 | 0.3 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.1 | 0.2 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 0.2 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.2 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 0.1 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.1 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.1 | PID PLK1 PATHWAY | PLK1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.4 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.3 | 2.1 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.3 | 1.2 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.3 | 0.9 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.2 | 0.6 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.5 | 0.5 | REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | Genes involved in Platelet activation, signaling and aggregation |
| 0.1 | 0.5 | REACTOME SIGNALING BY GPCR | Genes involved in Signaling by GPCR |
| 0.0 | 0.5 | REACTOME TRANSCRIPTION | Genes involved in Transcription |
| 0.1 | 0.4 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 0.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |