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Results for SWI5

Z-value: 0.84

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Transcription factors associated with SWI5

Gene Symbol Gene ID Gene Info
SWI5
S000002553 Transcription factor that recruits Mediator and Swi/Snf complexes

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SWI5YDR146C0.723.4e-05Click!

Activity profile of SWI5 motif

Sorted Z-values of SWI5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YFR055W 8.43
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YFR056C 8.12 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YER124C 5.91
DSE1
Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall
YDL055C 5.78
PSA1
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure
YLR154C 4.64
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YNL178W 3.79
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YIR021W 3.69
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YLR154W-C 3.54
TAR1
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand
YBR158W 3.46
AMN1
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YNL327W 3.43
EGT2
Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner
YFR054C 3.26 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YJL107C 3.19 Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi
YLR185W 3.07
RPL37A
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Bp and to rat L37 ribosomal protein
YJR094W-A 3.04
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YJL136C 3.00
RPS21B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein
YKL063C 2.87 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
YGL031C 2.74
RPL24A
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YFL022C 2.71
FRS2
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
YLR183C 2.52
TOS4
Transcription factor that binds to a number of promoter regions, particularly promoters of some genes involved in pheromone response and cell cycle; potential Cdc28p substrate; expression is induced in G1 by bound SBF
YKL164C 2.44
PIR1
O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle
YNL066W 2.43
SUN4
Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family
YNR067C 2.34
DSE4
Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother
YGR214W 2.32
RPS0A
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Bp; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal
YOR264W 2.31
DSE3
Daughter cell-specific protein, may help establish daughter fate
YIL018W 2.23
RPL2B
Protein component of the large (60S) ribosomal subunit, identical to Rpl2Ap and has similarity to E. coli L2 and rat L8 ribosomal proteins; expression is upregulated at low temperatures
YMR199W 2.23
CLN1
G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
YHR094C 2.15
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YLR154W-B 2.14 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YBL085W 2.11
BOI1
Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
YOR263C 2.10 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF DES3/YOR264W
YGL030W 2.08
RPL30
Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript
YLR300W 2.03
EXG1
Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes
YGL179C 2.00
TOS3
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
YDR044W 2.00
HEM13
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)
YJL106W 1.97
IME2
Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p
YPL062W 1.93 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation
YOR063W 1.89
RPL3
Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
YHR216W 1.88
IMD2
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation
YIL056W 1.87
VHR1
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations
YLR154W-A 1.87 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YOR342C 1.87 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus
YOR315W 1.86
SFG1
Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate
YKL182W 1.82
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YNL113W 1.82
RPC19
RNA polymerase subunit, common to RNA polymerases I and III
YKR094C 1.75
RPL40B
Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes
YDR385W 1.72
EFT2
Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
YKR092C 1.71
SRP40
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YDR025W 1.68
RPS11A
Protein component of the small (40S) ribosomal subunit; identical to Rps11Bp and has similarity to E. coli S17 and rat S11 ribosomal proteins
YDR345C 1.67
HXT3
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
YJR145C 1.62
RPS4A
Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein
YGL262W 1.62 Putative protein of unknown function; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein; YGL262W is not an essential gene
YER131W 1.61
RPS26B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein
YIL052C 1.51
RPL34B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Ap and has similarity to rat L34 ribosomal protein
YOL155C 1.51
HPF1
Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines
YGL028C 1.50
SCW11
Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p
YDL191W 1.47
RPL35A
Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and has similarity to rat L35 ribosomal protein
YHR180W-A 1.45 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps dubious ORF YHR180C-B and long terminal repeat YHRCsigma3
YNR001W-A 1.42 Dubious open reading frame unlikely to encode a functional protein; identified by homology
YJR105W 1.40
ADO1
Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle
YPL250W-A 1.40 Identified by fungal homology and RT-PCR
YGR189C 1.39
CRH1
Putative chitin transglycosidase, cell wall protein that functions in the transfer of chitin to beta(1-6)glucan; localizes to sites of polarized growth; expression is induced under cell wall stress conditions
YCR018C 1.35
SRD1
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
YGR118W 1.34
RPS23A
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Bp and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal
YKL219W 1.30
COS9
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
YKL062W 1.30
MSN4
Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
YBR191W 1.28
RPL21A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein
YLR413W 1.28 Putative protein of unknown function; YLR413W is not an essential gene
YBR088C 1.27
POL30
Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair
YGR050C 1.25 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YER052C 1.25
HOM3
Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis
YBR089W 1.24 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the verified gene POL30
YDR041W 1.21
RSM10
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins
YDR002W 1.21
YRB1
Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1
YGL158W 1.19
RCK1
Protein kinase involved in the response to oxidative stress; identified as suppressor of S. pombe cell cycle checkpoint mutations
YFR031C-A 1.19
RPL2A
Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins
YER180C-A 1.19
SLO1
Protein interacting with Arl3p, which is a GTPase of the Ras superfamily involved in vesicle-tethering at the Golgi; putative ortholog of human SCOCO
YDR040C 1.18
ENA1
P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
YOR050C 1.16 Hypothetical protein
YPL197C 1.15 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the ribosomal gene RPB7B
YHR053C 1.14
CUP1-1
Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C
YAL012W 1.14
CYS3
Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine
YLR150W 1.13
STM1
Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations
YML075C 1.12
HMG1
One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae
YDL047W 1.11
SIT4
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
YIR020W-A 1.10 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data
YOR313C 1.10
SPS4
Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage
YLR314C 1.09
CDC3
Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
YGR052W 1.09
FMP48
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation
YOR314W 1.08 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YJL200C 1.08
ACO2
Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol
YNL302C 1.08
RPS19B
Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Ap
YIR019C 1.06
MUC1
GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)
YIL053W 1.04
RHR2
Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress
YPR014C 1.00 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPR014C is not an essential gene
YFL034C-A 1.00
RPL22B
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Ap and to rat L22 ribosomal protein
YDR074W 0.99
TPS2
Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway
YGR249W 0.98
MGA1
Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants
YBL039C 0.97
URA7
Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis
YOR376W-A 0.97 Putative protein of unknown function; identified by fungal homology and RT-PCR
YDR384C 0.96
ATO3
Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family of putative transporters
YNL289W 0.96
PCL1
Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic cell cycle and regulation of morphogenesis, localizes to sites of polarized cell growth
YHR181W 0.96
SVP26
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment
YMR102C 0.96 Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene
YKL189W 0.95
HYM1
Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response
YER117W 0.94
RPL23B
Protein component of the large (60S) ribosomal subunit, identical to Rpl23Ap and has similarity to E. coli L14 and rat L23 ribosomal proteins
YOR073W-A 0.93 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially/completely overlaps the verified ORF CDC21/YOR074C; identified by RT-PCR
YJL222W-A 0.92 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YNR072W 0.92
HXT17
Hexose transporter, up-regulated in media containing raffinose and galactose at pH 7.7 versus pH 4.7, repressed by high levels of glucose
YML088W 0.91
UFO1
F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation
YNL153C 0.91
GIM3
Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
YDR095C 0.90 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDR133C 0.90 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C
YGR040W 0.90
KSS1
Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains
YMR049C 0.90
ERB1
Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
YBR210W 0.88
ERV15
Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p
YLR048W 0.88
RPS0B
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal
YLR029C 0.88
RPL15A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Bp and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA
YDL240W 0.88
LRG1
Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis
YJL150W 0.88 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YAL033W 0.87
POP5
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
YOR300W 0.87 Dubious open reading frame, unlikely to encode a protein; overlaps with verified gene BUD7/YOR299W; mutation affects bipolar budding and bud site selection, though phenotype could be due to the mutation's effects on BUD7
YLR286C 0.86
CTS1
Endochitinase, required for cell separation after mitosis; transcriptional activation during late G and early M cell cycle phases is mediated by transcription factor Ace2p
YOL124C 0.86
TRM11
Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain
YOL123W 0.86
HRP1
Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences
YHR010W 0.86
RPL27A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein
YGR086C 0.85
PIL1
Primary component of eisosomes, which are large immobile cell cortex structures associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; detected in phosphorylated state in mitochondria
YBR157C 0.84
ICS2
Protein of unknown function; null mutation does not confer any obvious defects in growth, spore germination, viability, or carbohydrate utilization
YDL211C 0.84 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
YGL178W 0.84
MPT5
Member of the Puf family of RNA-binding proteins; binds to mRNAs encoding chromatin modifiers and spindle pole body components; involved in longevity, maintenance of cell wall integrity, and sensitivity to and recovery from pheromone arrest
YCL063W 0.83
VAC17
Protein involved in vacuole inheritance; acts as a vacuole-specific receptor for myosin Myo2p
YLL044W 0.83 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLL044W and the overlapping gene RPL8B is reduced in the gcr1 null mutant
YCR099C 0.83 Putative protein of unknown function
YDR278C 0.82 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOL039W 0.82
RPP2A
Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
YKL211C 0.82
TRP3
Bifunctional enzyme exhibiting both indole-3-glycerol-phosphate synthase and anthranilate synthase activities, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p
YJL222W 0.82
VTH2
Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p/Vps10p, may be involved in vacuolar protein sorting
YLR262C 0.82
YPT6
GTPase, Ras-like GTP binding protein involved in the secretory pathway, required for fusion of endosome-derived vesicles with the late Golgi, maturation of the vacuolar carboxypeptidase Y; has similarity to the human GTPase, Rab6
YER102W 0.81
RPS8B
Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and has similarity to rat S8 ribosomal protein
YBL092W 0.81
RPL32
Protein component of the large (60S) ribosomal subunit, has similarity to rat L32 ribosomal protein; overexpression disrupts telomeric silencing
YGR148C 0.81
RPL24B
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YDR245W 0.80
MNN10
Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family
YOR096W 0.80
RPS7A
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins
YML124C 0.79
TUB3
Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p
YKL152C 0.79
GPM1
Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis
YOR046C 0.79
DBP5
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus; involved in translation termination
YOL161C 0.78
PAU20
Hypothetical protein
YER011W 0.78
TIR1
Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking
YKL153W 0.78 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLK153W and the overlapping essential gene GPM1 is reduced in the gcr1 null mutant
YHR143W 0.77
DSE2
Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP
YDL075W 0.77
RPL31A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YOL040C 0.76
RPS15
Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S19 and rat S15 ribosomal proteins
YKL110C 0.76
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YNR043W 0.75
MVD1
Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer
YGR285C 0.75
ZUO1
Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the Ssb proteins, as a chaperone for nascent polypeptide chains; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p
YHR055C 0.75
CUP1-2
Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C
YER181C 0.75 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative data; extensively overlaps a Ty1 LTR; protein product is detected in highly purified mitochondria in high-throughput studies
YBL108W 0.74 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YOL086C 0.74
ADH1
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
YOR234C 0.73
RPL33B
Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable
YAL067W-A 0.72 Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
YOR107W 0.71
RGS2
Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p
YLR112W 0.71 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YLR328W 0.71
NMA1
Nicotinic acid mononucleotide adenylyltransferase, involved in pathways of NAD biosynthesis, including the de novo, NAD(+) salvage, and nicotinamide riboside salvage pathways
YGR180C 0.71
RNR4
Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
YMR108W 0.71
ILV2
Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control
YLR049C 0.70 Putative protein of unknown function
YJL177W 0.70
RPL17B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins
YEL029C 0.69
BUD16
Putative pyridoxal kinase, key enzyme in vitamin B6 metabolism; involved in maintaining levels of pyridoxal 5'-phosphate, the active form of vitamin B6; required for genome integrity; homolog of E. coli PdxK; involved in bud-site selection
YOR025W 0.69
HST3
Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
YOR375C 0.69
GDH1
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources
YER046W 0.69
SPO73
Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensible for both nuclear divisions during meiosis
YLR110C 0.69
CCW12
Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor
YML074C 0.69
FPR3
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p
YLR333C 0.68
RPS25B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein
YOL109W 0.68
ZEO1
Peripheral membrane protein of the plasma membrane that interacts with Mid2p; regulates the cell integrity pathway mediated by Pkc1p and Slt2p; the authentic protein is detected in a phosphorylated state in highly purified mitochondria
YKL185W 0.68
ASH1
Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate
YBR300C 0.68 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YBR301W; YBR300C is not an essential gene
YGR090W 0.68
UTP22
Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
YLR448W 0.68
RPL6B
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA
YOR074C 0.68
CDC21
Thymidylate synthase, required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S
YBR106W 0.67
PHO88
Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations
YMR121C 0.66
RPL15B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA
YKR041W 0.66 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YNL079C 0.66
TPM1
Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently
YAL040C 0.65
CLN3
G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis
YIR020C 0.65 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YMR106C 0.65
YKU80
Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
YMR011W 0.65
HXT2
High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose
YBR190W 0.64 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the verified ribosomal protein gene RPL21A/YBR191W
YML063W 0.64
RPS1B
Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein
YER012W 0.63
PRE1
Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle
YHR020W 0.63 Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to proline-tRNA ligase; YHR020W is an essential gene
YPL037C 0.63
EGD1
Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b
YDR279W 0.63
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YOR029W 0.62 Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data
YKL218C 0.61
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YEL051W 0.61
VMA8
Subunit D of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; plays a role in the coupling of proton transport and ATP hydrolysis
YNL078W 0.61
NIS1
Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network
YMR217W 0.61
GUA1
GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation
YGR192C 0.60
TDH3
Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall

Network of associatons between targets according to the STRING database.

First level regulatory network of SWI5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.4 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
1.9 5.8 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
1.5 6.2 GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461)
1.4 15.1 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
0.9 2.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.8 5.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.7 2.1 GO:0006183 GTP biosynthetic process(GO:0006183) GTP metabolic process(GO:0046039)
0.6 1.9 GO:0043484 regulation of RNA splicing(GO:0043484) regulation of mRNA splicing, via spliceosome(GO:0048024)
0.6 1.7 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.5 8.7 GO:0006407 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.5 2.1 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.5 2.0 GO:0046688 response to copper ion(GO:0046688)
0.5 3.9 GO:0000372 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.4 1.3 GO:0097306 positive regulation of transcription from RNA polymerase II promoter in response to ethanol(GO:0061410) positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH(GO:0061422) cellular response to ethanol(GO:0071361) regulation of cell aging(GO:0090342) cellular response to alcohol(GO:0097306) regulation of replicative cell aging(GO:1900062)
0.4 1.7 GO:0019346 transsulfuration(GO:0019346)
0.4 1.3 GO:1901070 GMP biosynthetic process(GO:0006177) guanosine-containing compound biosynthetic process(GO:1901070)
0.4 0.8 GO:1903313 positive regulation of mRNA metabolic process(GO:1903313)
0.4 1.2 GO:0044209 AMP salvage(GO:0044209)
0.4 1.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.4 2.8 GO:0043457 regulation of cellular respiration(GO:0043457)
0.3 3.9 GO:0090529 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529)
0.3 1.3 GO:2000222 positive regulation of cell growth(GO:0030307) positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter(GO:1900461) positive regulation of pseudohyphal growth(GO:2000222)
0.3 0.9 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.3 1.2 GO:0009090 homoserine biosynthetic process(GO:0009090)
0.3 41.3 GO:0002181 cytoplasmic translation(GO:0002181)
0.3 0.9 GO:0035955 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
0.3 2.2 GO:0006814 sodium ion transport(GO:0006814)
0.3 0.8 GO:0023021 termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.3 1.1 GO:0031057 negative regulation of histone modification(GO:0031057)
0.3 0.8 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.3 0.8 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.3 0.3 GO:0051303 meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.2 3.7 GO:0001100 negative regulation of exit from mitosis(GO:0001100)
0.2 1.0 GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148)
0.2 1.0 GO:0098754 detoxification(GO:0098754)
0.2 0.9 GO:0051597 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
0.2 0.9 GO:0098609 agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.2 1.1 GO:0007535 donor selection(GO:0007535)
0.2 0.8 GO:0048313 Golgi inheritance(GO:0048313)
0.2 1.2 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.2 2.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 0.8 GO:0090337 regulation of formin-nucleated actin cable assembly(GO:0090337) positive regulation of formin-nucleated actin cable assembly(GO:0090338)
0.2 0.6 GO:0043419 urea catabolic process(GO:0043419)
0.2 2.2 GO:0030011 maintenance of cell polarity(GO:0030011)
0.2 0.6 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.2 1.0 GO:0009099 valine biosynthetic process(GO:0009099)
0.2 0.2 GO:0060188 regulation of protein desumoylation(GO:0060188)
0.2 1.1 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.2 0.8 GO:0000162 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.2 1.1 GO:0019655 glucose catabolic process(GO:0006007) glycolytic fermentation to ethanol(GO:0019655) glycolytic fermentation(GO:0019660) hexose catabolic process to ethanol(GO:1902707)
0.1 0.3 GO:0006827 high-affinity iron ion transmembrane transport(GO:0006827)
0.1 1.4 GO:0001402 signal transduction involved in filamentous growth(GO:0001402)
0.1 1.0 GO:0005992 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
0.1 0.7 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.1 0.3 GO:0070054 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) IRE1-mediated unfolded protein response(GO:0036498) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054)
0.1 0.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.4 GO:1900101 regulation of endoplasmic reticulum unfolded protein response(GO:1900101)
0.1 1.5 GO:0006273 lagging strand elongation(GO:0006273)
0.1 0.5 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
0.1 0.5 GO:0034473 U1 snRNA 3'-end processing(GO:0034473)
0.1 1.7 GO:0006037 cell wall chitin metabolic process(GO:0006037)
0.1 2.3 GO:0042797 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.7 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.1 1.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.4 GO:0045338 terpenoid metabolic process(GO:0006721) terpenoid biosynthetic process(GO:0016114) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.5 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.1 1.1 GO:0031070 intronic snoRNA processing(GO:0031070) intronic box C/D snoRNA processing(GO:0034965)
0.1 0.5 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.4 GO:0019419 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.1 0.1 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.1 0.9 GO:0033313 meiotic cell cycle checkpoint(GO:0033313) meiotic recombination checkpoint(GO:0051598)
0.1 1.0 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 1.0 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.2 GO:0071044 histone mRNA metabolic process(GO:0008334) histone mRNA catabolic process(GO:0071044)
0.1 0.7 GO:0070941 eisosome assembly(GO:0070941)
0.1 1.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 1.1 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 0.2 GO:0043065 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.1 0.6 GO:0007119 budding cell isotropic bud growth(GO:0007119)
0.1 0.6 GO:0001041 transcription from RNA polymerase III type 2 promoter(GO:0001009) transcription from a RNA polymerase III hybrid type promoter(GO:0001041)
0.1 1.2 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 1.2 GO:0007120 axial cellular bud site selection(GO:0007120)
0.1 0.3 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.1 0.2 GO:0001178 regulation of transcriptional start site selection at RNA polymerase II promoter(GO:0001178)
0.1 0.5 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054) negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.3 GO:0009847 spore germination(GO:0009847)
0.1 0.8 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1 1.8 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636) unsaturated fatty acid metabolic process(GO:0033559)
0.1 2.5 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.1 0.9 GO:0006817 phosphate ion transport(GO:0006817)
0.1 0.3 GO:2000134 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819) negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1 0.1 GO:0071168 establishment of protein localization to chromosome(GO:0070199) protein localization to chromatin(GO:0071168) establishment of protein localization to chromatin(GO:0071169)
0.1 2.0 GO:0002098 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.1 0.6 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 1.1 GO:0006415 translational termination(GO:0006415)
0.1 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.1 2.1 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 0.1 GO:0035307 positive regulation of phosphatase activity(GO:0010922) positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.1 0.2 GO:0071902 positive regulation of protein serine/threonine kinase activity(GO:0071902)
0.1 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.3 GO:0006448 regulation of translational elongation(GO:0006448)
0.1 0.5 GO:0048017 inositol lipid-mediated signaling(GO:0048017)
0.1 0.3 GO:0000296 spermine transport(GO:0000296)
0.1 0.8 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 0.6 GO:0000743 nuclear migration involved in conjugation with cellular fusion(GO:0000743)
0.1 0.3 GO:0031684 heterotrimeric G-protein complex cycle(GO:0031684)
0.1 0.5 GO:0009306 protein secretion(GO:0009306)
0.1 0.4 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 1.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.5 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.2 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 0.5 GO:0040031 snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031)
0.1 0.2 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 0.3 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 0.4 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.1 GO:0032262 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.1 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.7 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111) regulation of microtubule depolymerization(GO:0031114)
0.1 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 0.1 GO:0031384 regulation of initiation of mating projection growth(GO:0031384)
0.1 0.2 GO:0042992 regulation of transcription factor import into nucleus(GO:0042990) negative regulation of transcription factor import into nucleus(GO:0042992)
0.1 0.1 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.2 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1 0.6 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 0.4 GO:0031134 sister chromatid biorientation(GO:0031134)
0.1 0.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.8 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.2 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.1 1.0 GO:0043094 cellular metabolic compound salvage(GO:0043094)
0.1 0.2 GO:0051693 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) barbed-end actin filament capping(GO:0051016) actin filament capping(GO:0051693)
0.1 0.3 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.2 GO:0006571 tyrosine biosynthetic process(GO:0006571) L-phenylalanine biosynthetic process(GO:0009094) erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process(GO:1902223)
0.1 0.4 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.1 0.2 GO:0035753 maintenance of DNA trinucleotide repeats(GO:0035753)
0.1 0.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.1 0.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.4 GO:0000742 karyogamy involved in conjugation with cellular fusion(GO:0000742)
0.1 1.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.3 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304) endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.6 GO:0000011 vacuole inheritance(GO:0000011)
0.1 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.7 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0048255 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.0 0.9 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.2 GO:0042357 thiamine diphosphate biosynthetic process(GO:0009229) thiamine diphosphate metabolic process(GO:0042357)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.3 GO:0006901 vesicle coating(GO:0006901)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 1.1 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.0 1.5 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 0.7 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.3 GO:0010970 establishment of localization by movement along microtubule(GO:0010970) nuclear migration along microtubule(GO:0030473) organelle transport along microtubule(GO:0072384)
0.0 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0097033 mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0034963 box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.2 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.3 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.1 GO:0032102 negative regulation of macroautophagy(GO:0016242) negative regulation of response to external stimulus(GO:0032102) negative regulation of response to extracellular stimulus(GO:0032105) negative regulation of response to nutrient levels(GO:0032108)
0.0 0.3 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.1 GO:0034471 rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 1.1 GO:0000910 cytokinesis(GO:0000910)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0015691 cadmium ion transport(GO:0015691)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0015867 ATP transport(GO:0015867)
0.0 0.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.2 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.7 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.2 GO:0015677 copper ion import(GO:0015677)
0.0 1.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 3.0 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.3 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.8 GO:0006694 steroid biosynthetic process(GO:0006694) sterol biosynthetic process(GO:0016126)
0.0 0.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.1 GO:0072595 maintenance of protein location in nucleus(GO:0051457) maintenance of protein localization in organelle(GO:0072595)
0.0 0.1 GO:0061395 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061395) cellular response to arsenic-containing substance(GO:0071243)
0.0 0.2 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 1.0 GO:0006913 nucleocytoplasmic transport(GO:0006913)
0.0 1.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0015833 peptide transport(GO:0015833)
0.0 0.1 GO:0008299 isoprenoid metabolic process(GO:0006720) isoprenoid biosynthetic process(GO:0008299)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384) RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0097502 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.1 GO:0097549 heterochromatin organization involved in chromatin silencing(GO:0070868) chromatin organization involved in negative regulation of transcription(GO:0097549)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay(GO:0070481)
0.0 0.1 GO:0045862 positive regulation of proteolysis(GO:0045862)
0.0 0.2 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.0 0.1 GO:0016233 telomere capping(GO:0016233)
0.0 0.1 GO:0001196 regulation of mating-type specific transcription from RNA polymerase II promoter(GO:0001196) negative regulation of mating-type specific transcription from RNA polymerase II promoter(GO:0001198) regulation of cellular amine catabolic process(GO:0033241) negative regulation of mating-type specific transcription, DNA-templated(GO:0045894) positive regulation of mating-type specific transcription, DNA-templated(GO:0045895)
0.0 0.1 GO:0001109 promoter clearance during DNA-templated transcription(GO:0001109) promoter clearance from RNA polymerase II promoter(GO:0001111)
0.0 0.3 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.0 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of metal ion(GO:0051238) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.1 GO:0018208 protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208)
0.0 0.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.1 GO:0006673 inositolphosphoceramide metabolic process(GO:0006673)
0.0 0.1 GO:0009129 pyrimidine nucleoside monophosphate metabolic process(GO:0009129) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.1 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.1 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.0 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.0 GO:0070651 nonfunctional rRNA decay(GO:0070651)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0007015 actin filament organization(GO:0007015)
0.0 0.0 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.0 GO:0051647 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876) positive regulation of chromosome segregation(GO:0051984)
0.0 0.0 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.0 0.1 GO:0051666 actin cortical patch localization(GO:0051666)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.2 GO:0030428 cell septum(GO:0030428)
1.8 5.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.5 1.4 GO:0070545 PeBoW complex(GO:0070545)
0.4 35.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 25.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 1.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.4 1.5 GO:0032160 septin filament array(GO:0032160)
0.3 0.9 GO:0043529 GET complex(GO:0043529)
0.3 1.2 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
0.3 0.9 GO:0005827 polar microtubule(GO:0005827) tubulin complex(GO:0045298)
0.3 1.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.3 1.5 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 1.0 GO:0000131 incipient cellular bud site(GO:0000131)
0.2 0.7 GO:0031417 NatC complex(GO:0031417)
0.2 3.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 0.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2 0.8 GO:0044697 HICS complex(GO:0044697)
0.2 0.2 GO:0034455 t-UTP complex(GO:0034455)
0.2 1.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 0.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 1.0 GO:0034456 UTP-C complex(GO:0034456)
0.2 0.8 GO:0030689 Noc complex(GO:0030689)
0.2 0.8 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 0.6 GO:0005880 nuclear microtubule(GO:0005880)
0.2 1.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.4 GO:0071261 Ssh1 translocon complex(GO:0071261)
0.1 0.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 1.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.8 GO:0032126 eisosome(GO:0032126)
0.1 0.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.9 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.5 GO:0030869 RENT complex(GO:0030869)
0.1 1.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) multimeric ribonuclease P complex(GO:0030681)
0.1 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.3 GO:0000262 cytoplasmic chromosome(GO:0000229) mitochondrial chromosome(GO:0000262)
0.1 3.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.3 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.7 GO:0051233 spindle midzone(GO:0051233)
0.1 1.9 GO:0070210 Rpd3L-Expanded complex(GO:0070210)
0.1 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.7 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 0.4 GO:0034990 mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990)
0.1 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.0 GO:0005940 septin ring(GO:0005940)
0.1 0.7 GO:0032432 actin filament bundle(GO:0032432)
0.1 0.7 GO:0031933 nuclear heterochromatin(GO:0005720) nuclear telomeric heterochromatin(GO:0005724) telomeric heterochromatin(GO:0031933)
0.1 2.8 GO:0005844 polysome(GO:0005844)
0.1 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 6.5 GO:0005576 extracellular region(GO:0005576)
0.1 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.7 GO:0005688 U6 snRNP(GO:0005688)
0.1 14.3 GO:0005933 cellular bud(GO:0005933)
0.1 0.2 GO:0030874 nucleolar chromatin(GO:0030874)
0.1 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.4 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.8 GO:0034399 nuclear periphery(GO:0034399)
0.1 0.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.2 GO:0005825 half bridge of spindle pole body(GO:0005825)
0.1 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.1 2.2 GO:0005811 lipid particle(GO:0005811)
0.1 0.1 GO:0000133 polarisome(GO:0000133)
0.1 0.4 GO:0035339 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
0.1 0.2 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.1 0.9 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0032116 SMC loading complex(GO:0032116)
0.0 0.7 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0098827 cortical endoplasmic reticulum(GO:0032541) endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.3 GO:0031499 TRAMP complex(GO:0031499)
0.0 0.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.2 GO:0044453 nuclear outer membrane(GO:0005640) nuclear membrane part(GO:0044453)
0.0 1.5 GO:0005657 replication fork(GO:0005657)
0.0 0.3 GO:0005791 rough endoplasmic reticulum(GO:0005791) rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0000817 COMA complex(GO:0000817)
0.0 0.1 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0005823 central plaque of spindle pole body(GO:0005823)
0.0 0.6 GO:0016586 RSC complex(GO:0016586)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0070860 RNA polymerase I core factor complex(GO:0070860)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0034044 exomer complex(GO:0034044)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 1.1 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.1 GO:0097196 Shu complex(GO:0097196)
0.0 0.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0072379 ER membrane insertion complex(GO:0072379) TRC complex(GO:0072380)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.0 GO:0032545 CURI complex(GO:0032545)
0.0 0.1 GO:0034099 luminal surveillance complex(GO:0034099)
0.0 2.0 GO:0005730 nucleolus(GO:0005730)
0.0 0.6 GO:0005874 microtubule(GO:0005874)
0.0 0.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.0 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0000922 spindle pole(GO:0000922)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0070568 guanylyltransferase activity(GO:0070568)
1.5 9.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.3 5.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.0 3.8 GO:0042973 glucan endo-1,3-beta-D-glucosidase activity(GO:0042973)
0.9 2.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.9 2.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.7 2.0 GO:0008422 glucan exo-1,3-beta-glucosidase activity(GO:0004338) beta-glucosidase activity(GO:0008422)
0.6 3.8 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.5 2.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.4 2.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.4 1.7 GO:0016417 S-acyltransferase activity(GO:0016417)
0.4 1.1 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.4 1.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.4 1.4 GO:0019206 nucleoside kinase activity(GO:0019206)
0.3 0.3 GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity(GO:0003825)
0.3 1.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 1.8 GO:0005354 galactose transmembrane transporter activity(GO:0005354)
0.3 0.9 GO:0004805 trehalose-phosphatase activity(GO:0004805)
0.3 1.4 GO:0008536 Ran GTPase binding(GO:0008536)
0.3 0.9 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 13.0 GO:0019843 rRNA binding(GO:0019843)
0.3 0.8 GO:0004619 phosphoglycerate mutase activity(GO:0004619)
0.3 2.6 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.3 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 1.5 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 3.7 GO:0015926 glucosidase activity(GO:0015926)
0.2 43.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 3.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 0.6 GO:0016504 peptidase activator activity(GO:0016504)
0.2 0.6 GO:0004100 chitin synthase activity(GO:0004100)
0.2 0.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 3.6 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.2 0.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 1.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 3.3 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.2 0.7 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.2 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.2 1.5 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.2 0.5 GO:0019003 GDP binding(GO:0019003)
0.1 0.4 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1 0.4 GO:0035591 MAP-kinase scaffold activity(GO:0005078) signaling adaptor activity(GO:0035591)
0.1 0.7 GO:0043139 5'-3' DNA helicase activity(GO:0043139) ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.4 GO:0043812 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.9 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.9 GO:0043178 alcohol binding(GO:0043178)
0.1 0.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.4 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.5 GO:0016854 racemase and epimerase activity(GO:0016854)
0.1 0.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 1.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.4 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 2.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.6 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 1.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 1.2 GO:0043495 protein anchor(GO:0043495)
0.1 0.6 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.1 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.6 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.3 GO:0009922 fatty acid elongase activity(GO:0009922)
0.1 0.6 GO:0001008 RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) transcription factor activity, RNA polymerase III promoter sequence-specific binding, TFIIIB recruiting(GO:0001004) transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting(GO:0001005) transcription factor activity, RNA polymerase III type 2 promoter sequence-specific binding, TFIIIB recruiting(GO:0001008) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 0.3 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.1 0.5 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.0 GO:0015079 potassium ion transmembrane transporter activity(GO:0015079)
0.1 0.6 GO:0016778 diphosphotransferase activity(GO:0016778)
0.1 0.5 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) thiol oxidase activity(GO:0016972)
0.1 0.3 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.1 0.4 GO:0042123 glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124)
0.1 0.4 GO:0008312 7S RNA binding(GO:0008312)
0.1 0.2 GO:0008310 3'-5'-exodeoxyribonuclease activity(GO:0008296) single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.9 GO:0051015 actin filament binding(GO:0051015)
0.1 0.4 GO:0008198 ferrous iron binding(GO:0008198)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.1 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 0.3 GO:0019900 kinase binding(GO:0019900)
0.1 0.3 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 2.0 GO:0015631 tubulin binding(GO:0015631)
0.1 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 0.2 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.5 GO:0005216 ion channel activity(GO:0005216)
0.1 1.0 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 0.9 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.1 GO:0072341 modified amino acid binding(GO:0072341)
0.1 0.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.8 GO:0060090 binding, bridging(GO:0060090)
0.1 0.6 GO:0045182 translation regulator activity(GO:0045182)
0.1 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.5 GO:0015578 fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578)
0.0 0.3 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.0 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.4 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0001169 transcription factor activity, RNA polymerase I CORE element sequence-specific binding(GO:0001169) RNA polymerase I transcription factor binding(GO:0001179) transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting(GO:0001187)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 1.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.3 GO:0051920 thioredoxin peroxidase activity(GO:0008379) peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0050661 NADP binding(GO:0050661)
0.0 0.4 GO:0019239 deaminase activity(GO:0019239)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.2 GO:0001128 RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly(GO:0001128)
0.0 0.4 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.8 GO:0003779 actin binding(GO:0003779)
0.0 0.1 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.7 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0019201 nucleotide kinase activity(GO:0019201)
0.0 0.0 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.4 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.9 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 1.3 GO:0008289 lipid binding(GO:0008289)
0.0 0.1 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.2 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.0 1.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.5 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
0.0 0.1 GO:0016408 C-acyltransferase activity(GO:0016408)
0.0 0.0 GO:0019212 protein phosphatase inhibitor activity(GO:0004864) phosphatase inhibitor activity(GO:0019212)
0.0 0.0 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.0 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.0 GO:0000339 RNA cap binding(GO:0000339)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 PID SHP2 PATHWAY SHP2 signaling
0.3 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 0.9 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.2 0.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 0.7 PID E2F PATHWAY E2F transcription factor network
0.1 0.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 0.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 0.3 PID P73PATHWAY p73 transcription factor network
0.0 0.6 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 REACTOME INSULIN RECEPTOR SIGNALLING CASCADE Genes involved in Insulin receptor signalling cascade
0.7 15.7 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.4 1.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 0.8 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.2 0.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 0.7 REACTOME SIGNALING BY GPCR Genes involved in Signaling by GPCR
0.1 0.2 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 0.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.2 REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM Genes involved in Cytokine Signaling in Immune system
0.1 0.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 0.4 REACTOME METABOLISM OF RNA Genes involved in Metabolism of RNA
0.1 0.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME M G1 TRANSITION Genes involved in M/G1 Transition
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import