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Results for SFL1

Z-value: 1.23

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Transcription factors associated with SFL1

Gene Symbol Gene ID Gene Info
SFL1
S000005666 Transcriptional repressor and activator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SFL1YOR140W0.936.8e-12Click!

Activity profile of SFL1 motif

Sorted Z-values of SFL1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YAR053W 19.66 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YAL062W 15.53
GDH3
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources
YAR060C 13.64 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YHR212W-A 10.91 Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
YHR212C 10.78 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YKR097W 8.80
PCK1
Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol
YFR053C 8.78
HXK1
Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p
YFL051C 8.12 Putative protein of unknown function; YFL051C is not an essential gene
YLR307C-A 8.03 Putative protein of unknown function
YCL001W-B 7.76 Putative protein of unknown function; identified by homology
YMR206W 7.28 Putative protein of unknown function; YMR206W is not an essential gene
YER065C 7.10
ICL1
Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose
YKL217W 6.98
JEN1
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose
YGR142W 6.60
BTN2
v-SNARE binding protein that facilitates specific protein retrieval from a late endosome to the Golgi; modulates arginine uptake, possible role in mediating pH homeostasis between the vacuole and plasma membrane H(+)-ATPase
YMR118C 6.52 Protein of unknown function with similarity to succinate dehydrogenase cytochrome b subunit; YMR118C is not an essential gene
YOR192C 6.37
THI72
Transporter of thiamine or related compound; shares sequence similarity with Thi7p
YOR192C-C 6.15 Putative protein of unknown function; identified by expression profiling and mass spectrometry
YAR050W 6.04
FLO1
Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p
YGR067C 6.04 Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p
YOL084W 6.01
PHM7
Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole
YNL117W 5.90
MLS1
Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth in oleic acid medium
YDL169C 5.80
UGX2
Protein of unknown function, transcript accumulates in response to any combination of stress conditions
YPL171C 5.53
OYE3
Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism
YJR095W 5.45
SFC1
Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization
YMR107W 5.41
SPG4
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources
YPR192W 5.20
AQY1
Spore-specific water channel that mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance
YDR034C 5.17
LYS14
Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer
YIL057C 4.85 Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose
YKL031W 4.78 Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species
YAR047C 4.75 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YAL063C 4.75
FLO9
Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation
YLR122C 4.67 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR123C
YAR019W-A 4.67 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YPL223C 4.63
GRE1
Hydrophilin of unknown function; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway
YNL093W 4.55
YPT53
GTPase, similar to Ypt51p and Ypt52p and to mammalian rab5; required for vacuolar protein sorting and endocytosis
YLR346C 4.50 Putative protein of unknown function found in mitochondria; expression is regulated by transcription factors involved in pleiotropic drug resistance, Pdr1p and Yrr1p; YLR346C is not an essential gene
YER101C 4.34
AST2
Protein that may have a role in targeting of plasma membrane [H+]ATPase (Pma1p) to the plasma membrane, as suggested by analysis of genetic interactions
YDL210W 4.33
UGA4
Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane
YBR296C 4.29
PHO89
Na+/Pi cotransporter, active in early growth phase; similar to phosphate transporters of Neurospora crassa; transcription regulated by inorganic phosphate concentrations and Pho4p
YAR019C 4.26
CDC15
Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p
YEL012W 4.23
UBC8
Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro
YNL014W 4.22
HEF3
Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome; normally expressed in zinc deficient cells
YKL163W 4.16
PIR3
O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway
YLR123C 4.10 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR122C; contains characteristic aminoacyl-tRNA motif
YDR536W 4.02
STL1
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock
YPL021W 3.98
ECM23
Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth; homologous to Srd1p
YDR223W 3.80
CRF1
Transcriptional corepressor involved in the regulation of ribosomal protein gene transcription via the TOR signaling pathway and protein kinase A, phosphorylated by activated Yak1p which promotes accumulation of Crf1p in the nucleus
YGL045W 3.76
RIM8
Protein of unknown function, involved in the proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans PalF
YLR311C 3.72 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YPL230W 3.67
USV1
Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in protein folding, ATP binding, and cell wall biosynthesis
YDR343C 3.66
HXT6
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3
YMR013C 3.65
SEC59
Dolichol kinase, catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation
YJR048W 3.59
CYC1
Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration
YOL060C 3.57
MAM3
Protein required for normal mitochondrial morphology, has similarity to hemolysins
YBR201C-A 3.56 Putative protein of unknown function
YLR124W 3.53 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YDL223C 3.48
HBT1
Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (mating projection); mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis
YPL240C 3.46
HSP82
Hsp90 chaperone required for pheromone signaling and negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding and nucleotide addition; interacts with Cns1p, Cpr6p, Cpr7p, Sti1p
YJR150C 3.42
DAN1
Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth
YMR164C 3.39
MSS11
Transcription factor involved in regulation of invasive growth and starch degradation; controls the activation of MUC1 and STA2 in response to nutritional signals
YPR007C 3.37
REC8
Meiosis-specific component of sister chromatid cohesion complex; maintains cohesion between sister chromatids during meiosis I; maintains cohesion between centromeres of sister chromatids until meiosis II; homolog of S. pombe Rec8p
YER150W 3.33
SPI1
GPI-anchored cell wall protein involved in weak acid resistance; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; similar to Sed1p
YBR117C 3.29
TKL2
Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
YJL089W 3.19
SIP4
C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus
YER098W 3.18
UBP9
Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions
YBR200W-A 3.16 Putative protein of unknown function; identified by fungal homology and RT-PCR
YGR023W 3.14
MTL1
Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone-induced morphogenesis; suppresses rgd1 null mutations
YFL019C 3.13 Dubious open reading frame unlikely to encode a protein; YFL019C is not an essential gene
YLR334C 3.10 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps a stand-alone long terminal repeat sequence whose presence indicates a retrotransposition event occurred here
YDR542W 3.08
PAU10
Hypothetical protein
YKL161C 3.06 Protein kinase implicated in the Slt2p mitogen-activated (MAP) kinase signaling pathway; associates with Rlm1p
YGR043C 3.05
NQM1
Protein of unknown function; transcription is repressed by Mot1p and induced by alpha-factor and during diauxic shift; null mutant non-quiescent cells exhibit reduced reproductive capacity
YGR022C 3.04 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF MTL1/YGR023W
YLR111W 3.03 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YOL085W-A 3.01 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YOL085C
YDR379C-A 3.01 Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
YJR078W 3.00
BNA2
Putative tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p and Aft2p
YPL054W 2.98
LEE1
Zinc-finger protein of unknown function
YER097W 2.96 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YBL048W 2.89 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data
YER088C 2.87
DOT6
Protein of unknown function, involved in telomeric gene silencing and filamentation
YGR144W 2.84
THI4
Thiazole synthase, catalyzes formation of the thiazole moiety of thiamin pyrophosphate; required for thiamine biosynthesis and for mitochondrial genome stability
YLR307W 2.82
CDA1
Chitin deacetylase, together with Cda2p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall
YHR139C 2.81
SPS100
Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall
YLR149C 2.75 Putative protein of unknown function; YLR149C is not an essential gene
YGR286C 2.74
BIO2
Biotin synthase, catalyzes the conversion of dethiobiotin to biotin, which is the last step of the biotin biosynthesis pathway; complements E. coli bioB mutant
YAL039C 2.74
CYC3
Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)
YLR142W 2.73
PUT1
Proline oxidase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; PUT1 transcription is induced by Put3p in the presence of proline and the absence of a preferred nitrogen source
YML042W 2.71
CAT2
Carnitine acetyl-CoA transferase present in both mitochondria and peroxisomes, transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes
YDL054C 2.71
MCH1
Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport
YER116C 2.68
SLX8
Subunit of the Slx5-Slx8 substrate-specific ubiquitin ligase complex; stimulated by prior attachment of SUMO to the substrate
YMR017W 2.68
SPO20
Meiosis-specific subunit of the t-SNARE complex, required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; SNAP-25 homolog
YLR125W 2.68 Putative protein of unknown function; mutant has decreased Ty3 transposition; YLR125W is not an essential gene
YKL044W 2.66 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOR072W 2.66 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOR072W-A; diploid deletion strains are methotrexate, paraquat and wortmannin sensitive
YBL075C 2.63
SSA3
ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm
YDR342C 2.62
HXT7
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels
YKL171W 2.56 Putative protein of unknown function; predicted protein kinase; implicated in proteasome function; epitope-tagged protein localizes to the cytoplasm
YCR007C 2.56 Putative integral membrane protein, member of DUP240 gene family; YCR007C is not an essential gene
YOR343C 2.55 Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data
YOR346W 2.51
REV1
Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; involved in repair of abasic sites in damaged DNA
YOR345C 2.48 Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene REV1; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2
YMR034C 2.47 Putative transporter, member of the SLC10 carrier family; identified in a transposon mutagenesis screen as a gene involved in azole resistance; YMR034C is not an essential gene
YOR011W-A 2.46 Putative protein of unknown function
YGR256W 2.46
GND2
6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone
YDR540C 2.44
IRC4
Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YBL073W 2.43 Hypothetical protein; open reading frame overlaps 5' end of essential AAR2 gene encoding a component of the U5 snRNP required for splicing of U3 precursors
YKR102W 2.43
FLO10
Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation
YPL135W 2.42
ISU1
Conserved protein of the mitochondrial matrix, performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); isu1 isu2 double mutant is inviable
YLL060C 2.39
GTT2
Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p
YJR154W 2.39 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
YMR068W 2.38
AVO2
Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth
YNL180C 2.35
RHO5
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity
YJR160C 2.34
MPH3
Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph2p; encoded in a subtelomeric position in a region likely to have undergone duplication
YMR316C-B 2.32 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOR152C 2.31 Putative protein of unknown function; has no similarity to any known protein; YOR152C is not an essential gene
YMR165C 2.28
PAH1
Mg2+-dependent phosphatidate (PA) phosphatase, catalyzes the dephosphorylation of PA to yield diacylglycerol and Pi, responsible for de novo lipid synthesis; homologous to mammalian lipin 1
YEL039C 2.27
CYC7
Cytochrome c isoform 2, expressed under hypoxic conditions; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration
YDR218C 2.26
SPR28
Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; meiotic septin expressed at high levels during meiotic divisions and ascospore formation
YBL074C 2.24
AAR2
Component of the U5 snRNP, required for splicing of U3 precursors; originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron
YPR010C-A 2.24 Putative protein of unknown function; conserved among Saccharomyces sensu stricto species
YHR071W 2.24
PCL5
Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk), induced by Gcn4p at level of transcription, specifically required for Gcn4p degradation, may be sensor of cellular protein biosynthetic capacity
YIL162W 2.24
SUC2
Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively
YIL136W 2.24
OM45
Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane
YOR235W 2.23
IRC13
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutant displays increased levels of spontaneous Rad52 foci
YGR032W 2.21
GSC2
Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore wall; activity positively regulated by Rho1p and negatively by Smk1p; has similarity to an alternate catalytic subunit, Fks1p (Gsc1p)
YDR406W 2.20
PDR15
Plasma membrane ATP binding cassette (ABC) transporter, multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element
YKL071W 2.20 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
YMR014W 2.19
BUD22
Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
YEL028W 2.19 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YPR065W 2.17
ROX1
Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity
YMR244W 2.17 Putative protein of unknown function
YOR387C 2.16 Putative protein of unknown function; regulated by the metal-responsive Aft1p transcription factor; highly inducible in zinc-depleted conditions; localizes to the soluble fraction
YDR085C 2.16
AFR1
Alpha-factor pheromone receptor regulator, negatively regulates pheromone receptor signaling; required for normal mating projection (shmoo) formation; required for Spa2p to recruit Mpk1p to shmoo tip during mating; interacts with Cdc12p
YOR071C 2.16
NRT1
High-affinity nicotinamide riboside transporter; also transports thiamine with low affinity; shares sequence similarity with Thi7p and Thi72p; proposed to be involved in 5-fluorocytosine sensitivity
YGL258W-A 2.15 Putative protein of unknown function
YNL179C 2.13 Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; deletion in cyr1 mutant results in loss of stress resistance
YPR026W 2.11
ATH1
Acid trehalase required for utilization of extracellular trehalose
YLR356W 2.10 Putative protein of unknown function with similarity to SCM4; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YLR356W is not an essential gene
YMR317W 2.09 Putative protein of unknown function with some similarity to sialidase from Trypanosoma; YMR317W is not an essential gene
YHR211W 2.09
FLO5
Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p
YER187W 2.08 Putative protein of unknown function; induced in respiratory-deficient cells
YCL012C 2.05 Putative protein of unknown function; orthologs are present in S. bayanus, S. paradoxus and Ashbya gossypii; YCL012C is not an essential gene
YCL025C 2.04
AGP1
Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)
YLL056C 2.04 Putative protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in pleiotropic drug resistance (PDR) phenomenon; YLL056C is not an essential gene
YFL020C 2.03
PAU5
Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
YDR525W-A 2.03
SNA2
Protein of unknown function, has similarity to Pmp3p, which is involved in cation transport; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YBR035C 2.02
PDX3
Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism
YDR178W 2.00
SDH4
Membrane anchor subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone
YNR069C 1.97
BSC5
Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
YGL133W 1.95
ITC1
Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1
YLR164W 1.91 Mitochondrial inner membrane of unknown function; similar to Tim18p and Sdh4p; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YDR096W 1.88
GIS1
JmjC domain-containing histone demethylase; transcription factor involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1
YKL043W 1.87
PHD1
Transcriptional activator that enhances pseudohyphal growth; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental regulator; potential Cdc28p substrate
YLR342W 1.86
FKS1
Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling
YFR023W 1.86
PES4
Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation, similar to Mip6p
YIL160C 1.86
POT1
3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids
YPL222W 1.85
FMP40
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YBR169C 1.82
SSE2
Member of the heat shock protein 70 (HSP70) family; may be involved in protein folding; localized to the cytoplasm; highly homologous to the heat shock protein Sse1p
YMR081C 1.81
ISF1
Serine-rich, hydrophilic protein with similarity to Mbr1p; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant
YKL028W 1.80
TFA1
TFIIE large subunit, involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening
YMR271C 1.79
URA10
Minor orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in the de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; major OPRTase encoded by URA5
YER014C-A 1.78
BUD25
Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
YBL099W 1.77
ATP1
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated
YOR072W-A 1.76 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YOR072W; originally identified by fungal homology and RT-PCR
YDR022C 1.75
CIS1
Autophagy-specific protein required for autophagosome formation; may form a complex with Atg17p and Atg29p that localizes other proteins to the pre-autophagosomal structure; high-copy suppressor of CIK1 deletion
YCR005C 1.74
CIT2
Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle; expression is controlled by Rtg1p and Rtg2p transcription factors
YOR178C 1.73
GAC1
Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock
YPL183W-A 1.73
RTC6
Homolog of the prokaryotic ribosomal protein L36, likely to be a mitochondrial ribosomal protein coded in the nuclear genome; null mutation suppresses cdc13-1 temperature sensitivity
YPL089C 1.73
RLM1
MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p
YMR103C 1.73 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YMR096W 1.72
SNZ1
Protein involved in vitamin B6 biosynthesis; member of a stationary phase-induced gene family; coregulated with SNO1; interacts with Sno1p and with Yhr198p, perhaps as a multiprotein complex containing other Snz and Sno proteins
YAR035W 1.72
YAT1
Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated
YJR151C 1.72
DAN4
Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth
YDL244W 1.70
THI13
Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13
YHR145C 1.70 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YKL032C 1.69
IXR1
Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b
YBR226C 1.68 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YBR225W
YPR193C 1.68
HPA2
Tetrameric histone acetyltransferase with similarity to Gcn5p, Hat1p, Elp3p, and Hpa3p; acetylates histones H3 and H4 in vitro and exhibits autoacetylation activity
YPR027C 1.67 Putative protein of unknown function
YPL271W 1.67
ATP15
Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated
YLR366W 1.66 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR364C-A
YGL163C 1.66
RAD54
DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family
YOR214C 1.65 Putative protein of unknown function; YOR214C is not an essential gene
YLR425W 1.65
TUS1
Guanine nucleotide exchange factor (GEF) that functions to modulate Rho1p activity as part of the cell integrity signaling pathway; multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation; potential Cdc28p substrate
YGR039W 1.64 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the Autonomously Replicating Sequence ARS722
YOL035C 1.63 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGR225W 1.63
AMA1
Activator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis
YPL258C 1.63
THI21
Hydroxymethylpyrimidine phosphate kinase, involved in the last steps in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p
YBL100C 1.62 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the 5' end of ATP1
YDR043C 1.62
NRG1
Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response
YJR153W 1.60
PGU1
Endo-polygalacturonase, pectolytic enzyme that hydrolyzes the alpha-1,4-glycosidic bonds in the rhamnogalacturonan chains in pectins
YHR006W 1.60
STP2
Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes
YLR152C 1.60 Putative protein of unknown function; YLR152C is not an essential gene
YGL205W 1.60
POX1
Fatty-acyl coenzyme A oxidase, involved in the fatty acid beta-oxidation pathway; localized to the peroxisomal matrix
YFL055W 1.59
AGP3
Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation; plays a role in regulating Ty1 transposition
YFR026C 1.58 Putative protein of unknown function
YMR141C 1.57 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGL191W 1.56
COX13
Subunit VIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP
YHR048W 1.56
YHK8
Presumed antiporter of the DHA1 family of multidrug resistance transporters; contains 12 predicted transmembrane spans; expression of gene is up-regulated in cells exhibiting reduced susceptibility to azoles

Network of associatons between targets according to the STRING database.

First level regulatory network of SFL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
2.9 17.4 GO:0000501 flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501)
2.8 8.5 GO:0015888 thiamine transport(GO:0015888)
2.4 7.2 GO:0015755 fructose transport(GO:0015755)
2.0 2.0 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
1.8 3.7 GO:0061416 regulation of transcription from RNA polymerase II promoter in response to salt stress(GO:0061416)
1.7 7.0 GO:0006848 pyruvate transport(GO:0006848)
1.7 15.1 GO:0006097 glyoxylate cycle(GO:0006097)
1.7 3.3 GO:0035948 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061413) positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061414)
1.5 4.4 GO:0009437 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
1.3 1.3 GO:0046487 glyoxylate metabolic process(GO:0046487)
1.3 5.2 GO:0010688 negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter(GO:0010688)
1.2 3.7 GO:0015740 C4-dicarboxylate transport(GO:0015740)
1.1 5.5 GO:2000284 positive regulation of cellular amino acid biosynthetic process(GO:2000284)
1.1 4.4 GO:0006075 (1->3)-beta-D-glucan biosynthetic process(GO:0006075)
1.0 9.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.0 1.0 GO:0071361 positive regulation of transcription from RNA polymerase II promoter in response to ethanol(GO:0061410) cellular response to ethanol(GO:0071361) cellular response to alcohol(GO:0097306)
1.0 2.9 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.9 2.7 GO:0006562 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.8 4.1 GO:0015793 glycerol transport(GO:0015793)
0.8 3.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.8 2.3 GO:0019627 urea metabolic process(GO:0019627)
0.8 3.1 GO:0015847 putrescine transport(GO:0015847)
0.8 3.8 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.8 1.5 GO:0034287 detection of chemical stimulus(GO:0009593) detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) detection of stimulus(GO:0051606)
0.7 2.1 GO:0005993 trehalose catabolic process(GO:0005993)
0.7 0.7 GO:0036257 multivesicular body organization(GO:0036257)
0.7 1.3 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.7 4.6 GO:0071467 cellular response to pH(GO:0071467)
0.6 5.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.6 1.9 GO:0006545 glycine biosynthetic process(GO:0006545)
0.6 3.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.6 1.2 GO:0046323 glucose import(GO:0046323)
0.6 2.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.6 10.0 GO:0042724 thiamine biosynthetic process(GO:0009228) thiamine-containing compound biosynthetic process(GO:0042724)
0.6 2.3 GO:0000023 maltose metabolic process(GO:0000023)
0.6 5.2 GO:0046352 disaccharide catabolic process(GO:0046352)
0.6 2.9 GO:0034627 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627)
0.6 4.0 GO:0030026 cellular manganese ion homeostasis(GO:0030026) manganese ion homeostasis(GO:0055071)
0.6 1.7 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.5 2.7 GO:0016242 negative regulation of macroautophagy(GO:0016242) negative regulation of response to external stimulus(GO:0032102) negative regulation of response to extracellular stimulus(GO:0032105) negative regulation of response to nutrient levels(GO:0032108)
0.5 2.6 GO:0034487 amino acid transmembrane export from vacuole(GO:0032974) vacuolar transmembrane transport(GO:0034486) vacuolar amino acid transmembrane transport(GO:0034487) amino acid transmembrane export(GO:0044746)
0.5 1.6 GO:0051101 positive regulation of DNA binding(GO:0043388) regulation of DNA binding(GO:0051101)
0.5 3.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.5 5.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.5 0.5 GO:1900544 positive regulation of nucleotide metabolic process(GO:0045981) positive regulation of purine nucleotide metabolic process(GO:1900544)
0.5 2.0 GO:0016577 protein demethylation(GO:0006482) protein dealkylation(GO:0008214) histone demethylation(GO:0016577) demethylation(GO:0070988)
0.5 2.0 GO:0000949 aromatic amino acid family catabolic process to alcohol via Ehrlich pathway(GO:0000949)
0.5 4.9 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.5 1.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.5 1.4 GO:0034389 lipid particle organization(GO:0034389)
0.5 1.4 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.5 4.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.5 1.4 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.5 2.3 GO:0001113 transcriptional open complex formation at RNA polymerase II promoter(GO:0001113)
0.5 3.2 GO:0051322 anaphase(GO:0051322)
0.5 0.9 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.4 2.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.4 1.3 GO:0006108 malate metabolic process(GO:0006108)
0.4 7.9 GO:0008645 hexose transport(GO:0008645) monosaccharide transport(GO:0015749)
0.4 0.9 GO:0006740 NADPH regeneration(GO:0006740)
0.4 1.3 GO:0034764 positive regulation of lipid transport(GO:0032370) regulation of sterol transport(GO:0032371) positive regulation of sterol transport(GO:0032373) positive regulation of transmembrane transport(GO:0034764) regulation of sterol import by regulation of transcription from RNA polymerase II promoter(GO:0035968) positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter(GO:0035969) regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) regulation of sterol import(GO:2000909) positive regulation of sterol import(GO:2000911)
0.4 1.7 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077) positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.4 1.7 GO:0071456 cellular response to hypoxia(GO:0071456)
0.4 5.9 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.4 3.8 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.4 1.2 GO:0042843 D-xylose catabolic process(GO:0042843)
0.4 4.1 GO:0000272 polysaccharide catabolic process(GO:0000272)
0.4 0.8 GO:0009450 gamma-aminobutyric acid metabolic process(GO:0009448) gamma-aminobutyric acid catabolic process(GO:0009450)
0.4 1.6 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.4 0.8 GO:0090295 nitrogen catabolite repression of transcription(GO:0090295)
0.4 0.8 GO:1903321 negative regulation of protein ubiquitination(GO:0031397) negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.4 1.5 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.4 1.5 GO:0071168 protein localization to chromatin(GO:0071168)
0.4 1.5 GO:0019748 secondary metabolic process(GO:0019748)
0.4 1.5 GO:0046688 response to copper ion(GO:0046688)
0.4 1.1 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.3 2.1 GO:0006768 biotin metabolic process(GO:0006768) biotin biosynthetic process(GO:0009102)
0.3 0.7 GO:0006527 arginine catabolic process(GO:0006527)
0.3 1.0 GO:0019541 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) short-chain fatty acid catabolic process(GO:0019626) propionate catabolic process, 2-methylcitrate cycle(GO:0019629)
0.3 0.7 GO:0006538 glutamate catabolic process(GO:0006538)
0.3 0.3 GO:2000219 positive regulation of invasive growth in response to glucose limitation by positive regulation of transcription from RNA polymerase II promoter(GO:0036095) positive regulation of invasive growth in response to glucose limitation(GO:2000219)
0.3 1.6 GO:0046058 cAMP metabolic process(GO:0046058)
0.3 2.5 GO:0046686 response to cadmium ion(GO:0046686)
0.3 1.5 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.3 0.6 GO:0006824 cobalt ion transport(GO:0006824)
0.3 1.2 GO:0000435 regulation of transcription from RNA polymerase II promoter by galactose(GO:0000431) positive regulation of transcription from RNA polymerase II promoter by galactose(GO:0000435)
0.3 0.6 GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.3 1.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.3 1.8 GO:0016241 positive regulation of macroautophagy(GO:0016239) regulation of macroautophagy(GO:0016241)
0.3 3.3 GO:0006817 phosphate ion transport(GO:0006817)
0.3 4.7 GO:0007266 Rho protein signal transduction(GO:0007266)
0.3 0.9 GO:0090527 actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.3 0.9 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.3 1.4 GO:0000436 carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.3 2.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.3 0.3 GO:0043270 positive regulation of ion transport(GO:0043270)
0.3 0.6 GO:0043970 histone H3 acetylation(GO:0043966) histone H3-K9 acetylation(GO:0043970) histone H3-K14 acetylation(GO:0044154) histone H3-K9 modification(GO:0061647)
0.3 0.8 GO:0000409 regulation of transcription by galactose(GO:0000409) positive regulation of transcription by galactose(GO:0000411)
0.3 0.8 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of metal ion(GO:0051238) sequestering of iron ion(GO:0097577)
0.3 0.3 GO:0034225 cellular response to zinc ion starvation(GO:0034224) regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation(GO:0034225)
0.3 0.8 GO:0090399 replicative senescence(GO:0090399)
0.3 5.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.3 0.8 GO:0044783 G1 DNA damage checkpoint(GO:0044783)
0.3 3.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.3 4.9 GO:0001101 response to acid chemical(GO:0001101)
0.3 1.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.3 0.5 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.3 1.1 GO:0006598 polyamine catabolic process(GO:0006598)
0.3 2.9 GO:0016925 protein sumoylation(GO:0016925)
0.3 0.5 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.3 0.8 GO:0045117 azole transport(GO:0045117)
0.3 3.5 GO:0031321 ascospore-type prospore assembly(GO:0031321)
0.2 0.7 GO:0032874 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.2 1.0 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.2 0.7 GO:0032365 intracellular lipid transport(GO:0032365)
0.2 3.4 GO:0000767 cell morphogenesis involved in conjugation with cellular fusion(GO:0000753) cell morphogenesis involved in conjugation(GO:0000767)
0.2 3.6 GO:0015918 sterol transport(GO:0015918)
0.2 1.4 GO:0070058 tRNA gene clustering(GO:0070058)
0.2 2.1 GO:0000196 MAPK cascade involved in cell wall organization or biogenesis(GO:0000196)
0.2 2.9 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.2 1.6 GO:0000114 obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114)
0.2 0.9 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.2 0.7 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 3.5 GO:0016575 histone deacetylation(GO:0016575)
0.2 0.9 GO:0010677 negative regulation of cellular carbohydrate metabolic process(GO:0010677) negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of carbohydrate metabolic process(GO:0045912) negative regulation of glycogen metabolic process(GO:0070874)
0.2 1.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.2 0.2 GO:0032071 regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071)
0.2 1.0 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.2 0.6 GO:0030491 heteroduplex formation(GO:0030491)
0.2 0.6 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2 0.8 GO:0055088 lipid homeostasis(GO:0055088)
0.2 1.6 GO:0072348 sulfur compound transport(GO:0072348)
0.2 0.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 0.8 GO:0001308 negative regulation of chromatin silencing involved in replicative cell aging(GO:0001308)
0.2 1.2 GO:0000266 mitochondrial fission(GO:0000266)
0.2 1.3 GO:0015891 siderophore transport(GO:0015891)
0.2 0.9 GO:0051260 protein homooligomerization(GO:0051260)
0.2 0.9 GO:0030308 negative regulation of cell growth(GO:0030308) negative regulation of pseudohyphal growth(GO:2000221)
0.2 1.1 GO:0046020 negative regulation of transcription by pheromones(GO:0045996) negative regulation of transcription from RNA polymerase II promoter by pheromones(GO:0046020)
0.2 1.4 GO:0031167 rRNA methylation(GO:0031167)
0.2 0.4 GO:0070873 regulation of glycogen biosynthetic process(GO:0005979) regulation of glycogen metabolic process(GO:0070873)
0.2 0.9 GO:0032048 cardiolipin metabolic process(GO:0032048)
0.2 1.6 GO:0042775 respiratory electron transport chain(GO:0022904) ATP synthesis coupled electron transport(GO:0042773) mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.2 0.4 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.2 0.5 GO:0006000 fructose metabolic process(GO:0006000)
0.2 0.7 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993)
0.2 2.4 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress(GO:0036003)
0.2 0.7 GO:0019405 alditol catabolic process(GO:0019405) glycerol catabolic process(GO:0019563)
0.2 1.0 GO:0006279 premeiotic DNA replication(GO:0006279)
0.2 0.3 GO:0061013 regulation of mRNA catabolic process(GO:0061013)
0.2 0.3 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) protein-DNA complex remodeling(GO:0001120) macromolecular complex remodeling(GO:0034367)
0.2 1.0 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.2 1.2 GO:0015908 fatty acid transport(GO:0015908)
0.2 0.8 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.2 0.8 GO:0043605 allantoin metabolic process(GO:0000255) allantoin catabolic process(GO:0000256) cellular amide catabolic process(GO:0043605)
0.2 0.5 GO:0001927 exocyst assembly(GO:0001927)
0.2 0.2 GO:0009847 spore germination(GO:0009847)
0.2 5.2 GO:0006865 amino acid transport(GO:0006865)
0.2 1.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.2 2.2 GO:0001558 regulation of cell growth(GO:0001558)
0.2 0.5 GO:0031297 replication fork processing(GO:0031297)
0.2 3.0 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.2 0.9 GO:0006855 drug transmembrane transport(GO:0006855)
0.2 1.1 GO:0097034 mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.3 GO:0001080 nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) nitrogen catabolite activation of transcription(GO:0090294)
0.1 1.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.4 GO:0008105 asymmetric protein localization(GO:0008105)
0.1 2.8 GO:0016579 protein deubiquitination(GO:0016579)
0.1 0.4 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.1 0.6 GO:0001881 receptor recycling(GO:0001881) protein import into peroxisome matrix, receptor recycling(GO:0016562) receptor metabolic process(GO:0043112)
0.1 0.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 5.5 GO:0009060 aerobic respiration(GO:0009060)
0.1 1.1 GO:0070272 proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.5 GO:0097271 protein localization to bud neck(GO:0097271)
0.1 0.5 GO:0072417 cellular response to biotic stimulus(GO:0071216) response to cell cycle checkpoint signaling(GO:0072396) response to mitotic cell cycle checkpoint signaling(GO:0072414) response to spindle checkpoint signaling(GO:0072417) response to mitotic spindle checkpoint signaling(GO:0072476) response to mitotic cell cycle spindle assembly checkpoint signaling(GO:0072479) response to spindle assembly checkpoint signaling(GO:0072485) negative regulation of protein import into nucleus during spindle assembly checkpoint(GO:1901925)
0.1 0.9 GO:0043488 regulation of RNA stability(GO:0043487) regulation of mRNA stability(GO:0043488)
0.1 1.9 GO:0000209 protein polyubiquitination(GO:0000209)
0.1 0.8 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.4 GO:0071248 cellular response to metal ion(GO:0071248)
0.1 0.6 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 1.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 2.6 GO:0006312 mitotic recombination(GO:0006312)
0.1 0.4 GO:0045003 double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 0.4 GO:0042744 hydrogen peroxide metabolic process(GO:0042743) hydrogen peroxide catabolic process(GO:0042744)
0.1 0.5 GO:0072329 monocarboxylic acid catabolic process(GO:0072329)
0.1 7.5 GO:0048468 ascospore formation(GO:0030437) cell development(GO:0048468)
0.1 0.8 GO:0006639 neutral lipid metabolic process(GO:0006638) acylglycerol metabolic process(GO:0006639) triglyceride metabolic process(GO:0006641)
0.1 0.5 GO:0015893 drug transport(GO:0015893)
0.1 0.2 GO:1903313 positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.1 0.6 GO:0009231 riboflavin metabolic process(GO:0006771) riboflavin biosynthetic process(GO:0009231)
0.1 0.3 GO:0018105 peptidyl-serine phosphorylation(GO:0018105) peptidyl-serine modification(GO:0018209)
0.1 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.7 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 1.4 GO:0005977 glycogen metabolic process(GO:0005977) energy reserve metabolic process(GO:0006112)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.6 GO:0070096 mitochondrial outer membrane translocase complex assembly(GO:0070096)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.3 GO:0045033 peroxisome inheritance(GO:0045033)
0.1 0.2 GO:0001196 regulation of mating-type specific transcription from RNA polymerase II promoter(GO:0001196) negative regulation of mating-type specific transcription from RNA polymerase II promoter(GO:0001198) negative regulation of mating-type specific transcription, DNA-templated(GO:0045894)
0.1 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.2 GO:2001023 cellular response to drug(GO:0035690) regulation of response to drug(GO:2001023) positive regulation of response to drug(GO:2001025) regulation of cellular response to drug(GO:2001038) positive regulation of cellular response to drug(GO:2001040)
0.1 0.2 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.1 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.5 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.3 GO:0071450 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.3 GO:2000001 regulation of cell cycle checkpoint(GO:1901976) negative regulation of cell cycle checkpoint(GO:1901977) regulation of DNA damage checkpoint(GO:2000001) negative regulation of DNA damage checkpoint(GO:2000002) negative regulation of response to DNA damage stimulus(GO:2001021)
0.1 0.3 GO:0034762 regulation of transmembrane transport(GO:0034762)
0.1 0.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 0.3 GO:0046503 glycerophospholipid catabolic process(GO:0046475) glycerolipid catabolic process(GO:0046503)
0.1 0.4 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.1 0.6 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 0.1 GO:0098656 anion transmembrane transport(GO:0098656)
0.1 0.1 GO:0032872 stress-activated protein kinase signaling cascade(GO:0031098) regulation of stress-activated MAPK cascade(GO:0032872) stress-activated MAPK cascade(GO:0051403) regulation of stress-activated protein kinase signaling cascade(GO:0070302)
0.1 0.2 GO:0045895 positive regulation of mating-type specific transcription, DNA-templated(GO:0045895)
0.1 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.7 GO:0052803 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.1 0.2 GO:0006546 glycine catabolic process(GO:0006546)
0.1 0.3 GO:0043954 cellular component maintenance(GO:0043954)
0.1 0.4 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.1 0.2 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.1 0.2 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.1 0.4 GO:0055074 cellular calcium ion homeostasis(GO:0006874) calcium ion homeostasis(GO:0055074)
0.1 0.6 GO:1905037 autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.1 0.6 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 0.2 GO:0009746 response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.1 1.7 GO:0006200 obsolete ATP catabolic process(GO:0006200)
0.1 0.2 GO:0031578 mitotic spindle orientation checkpoint(GO:0031578)
0.1 0.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.5 GO:0006826 iron ion transport(GO:0006826)
0.1 0.7 GO:0000147 actin cortical patch assembly(GO:0000147) actin cortical patch organization(GO:0044396)
0.1 0.6 GO:0042026 protein refolding(GO:0042026)
0.1 0.2 GO:0006276 plasmid maintenance(GO:0006276)
0.1 2.7 GO:0030435 sporulation resulting in formation of a cellular spore(GO:0030435)
0.1 1.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 0.3 GO:0034508 centromere complex assembly(GO:0034508) kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.1 0.2 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.1 0.2 GO:0048313 Golgi inheritance(GO:0048313)
0.1 0.4 GO:0000321 re-entry into mitotic cell cycle after pheromone arrest(GO:0000321)
0.1 1.0 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.0 GO:0015688 iron chelate transport(GO:0015688)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059) response to decreased oxygen levels(GO:0036293) cellular response to decreased oxygen levels(GO:0036294) response to oxygen levels(GO:0070482) cellular response to oxygen levels(GO:0071453) cellular response to anoxia(GO:0071454)
0.0 0.4 GO:0019878 lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 0.0 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.0 0.7 GO:0043085 positive regulation of catalytic activity(GO:0043085)
0.0 0.3 GO:0033108 mitochondrial respiratory chain complex assembly(GO:0033108)
0.0 0.3 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of mitotic spindle localization(GO:0040001) establishment of spindle orientation(GO:0051294)
0.0 0.0 GO:0009268 response to pH(GO:0009268)
0.0 0.3 GO:0034401 chromatin organization involved in regulation of transcription(GO:0034401)
0.0 0.2 GO:0000080 mitotic G1 phase(GO:0000080) G1 phase(GO:0051318)
0.0 0.3 GO:0034087 establishment of sister chromatid cohesion(GO:0034085) establishment of mitotic sister chromatid cohesion(GO:0034087)
0.0 0.3 GO:0045005 DNA-dependent DNA replication maintenance of fidelity(GO:0045005)
0.0 0.2 GO:0051292 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:0000161 MAPK cascade involved in osmosensory signaling pathway(GO:0000161)
0.0 3.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.3 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.2 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.3 GO:0046854 lipid phosphorylation(GO:0046834) phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0051180 vitamin transport(GO:0051180)
0.0 0.0 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0060963 positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter(GO:0060963)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0035753 maintenance of DNA trinucleotide repeats(GO:0035753)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0010647 positive regulation of cell communication(GO:0010647)
0.0 0.1 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.0 GO:0006544 glycine metabolic process(GO:0006544)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.1 GO:0071850 mitotic cell cycle arrest in response to pheromone(GO:0000751) mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:0010388 protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.0 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:0015856 cytosine transport(GO:0015856) purine-containing compound transmembrane transport(GO:0072530)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0000148 1,3-beta-D-glucan synthase complex(GO:0000148)
0.9 4.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.8 10.9 GO:0005619 ascospore wall(GO:0005619)
0.8 9.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.8 3.8 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.7 2.2 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.7 2.2 GO:0000113 nucleotide-excision repair factor 4 complex(GO:0000113)
0.7 2.7 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.7 2.0 GO:0030061 mitochondrial crista(GO:0030061)
0.6 12.1 GO:0070469 respiratory chain(GO:0070469)
0.5 1.5 GO:0031422 RecQ helicase-Topo III complex(GO:0031422)
0.5 2.0 GO:0008623 CHRAC(GO:0008623)
0.5 1.0 GO:0032126 eisosome(GO:0032126)
0.5 2.0 GO:0001400 mating projection base(GO:0001400)
0.5 3.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 1.4 GO:0045265 mitochondrial proton-transporting ATP synthase, stator stalk(GO:0000274) proton-transporting ATP synthase, stator stalk(GO:0045265)
0.4 2.6 GO:0031932 TORC2 complex(GO:0031932)
0.4 1.2 GO:0032389 MutLalpha complex(GO:0032389)
0.4 1.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.4 1.1 GO:0045240 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial oxoglutarate dehydrogenase complex(GO:0009353) dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.3 13.2 GO:0005770 late endosome(GO:0005770)
0.3 4.9 GO:0033698 Rpd3L complex(GO:0033698)
0.3 0.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.3 1.9 GO:0034967 Set3 complex(GO:0034967)
0.3 1.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 0.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 0.9 GO:0032116 SMC loading complex(GO:0032116)
0.2 1.5 GO:0034657 GID complex(GO:0034657)
0.2 10.6 GO:0031225 anchored component of membrane(GO:0031225)
0.2 0.6 GO:0000111 nucleotide-excision repair factor 2 complex(GO:0000111)
0.2 0.6 GO:0030874 nucleolar chromatin(GO:0030874)
0.2 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 3.3 GO:0031307 intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307)
0.2 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.2 0.2 GO:0005775 vacuolar lumen(GO:0005775)
0.2 0.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 0.7 GO:0000796 condensin complex(GO:0000796) nuclear condensin complex(GO:0000799)
0.2 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.8 GO:0072380 ER membrane insertion complex(GO:0072379) TRC complex(GO:0072380)
0.2 0.5 GO:0031901 early endosome membrane(GO:0031901)
0.2 2.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 3.3 GO:0042763 prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764)
0.2 8.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 1.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.8 GO:0090544 SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544)
0.1 2.2 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.1 GO:0005871 kinesin complex(GO:0005871)
0.1 0.4 GO:0035649 Nrd1 complex(GO:0035649)
0.1 5.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.0 GO:0048188 histone methyltransferase complex(GO:0035097) Set1C/COMPASS complex(GO:0048188)
0.1 0.4 GO:0031518 CBF3 complex(GO:0031518)
0.1 0.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.7 GO:0000112 nucleotide-excision repair factor 3 complex(GO:0000112)
0.1 4.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.4 GO:0005769 early endosome(GO:0005769)
0.1 0.2 GO:0030478 actin cap(GO:0030478)
0.1 0.5 GO:0035361 Cul8-RING ubiquitin ligase complex(GO:0035361)
0.1 0.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 2.4 GO:0000322 storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324)
0.1 0.6 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 1.9 GO:0016592 mediator complex(GO:0016592)
0.1 0.3 GO:0032176 split septin rings(GO:0032176) cellular bud neck split septin rings(GO:0032177)
0.1 0.7 GO:0000145 exocyst(GO:0000145)
0.1 0.4 GO:0044233 ERMES complex(GO:0032865) ER-mitochondrion membrane contact site(GO:0044233)
0.1 3.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.1 1.4 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.0 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.3 GO:0030287 cell wall-bounded periplasmic space(GO:0030287)
0.1 0.2 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271)
0.1 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.3 GO:0033101 cellular bud membrane(GO:0033101)
0.1 1.4 GO:0098573 intrinsic component of mitochondrial membrane(GO:0098573)
0.1 0.5 GO:0000795 synaptonemal complex(GO:0000795)
0.1 9.9 GO:0005774 vacuolar membrane(GO:0005774)
0.1 0.1 GO:0070211 Snt2C complex(GO:0070211)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 34.3 GO:0005739 mitochondrion(GO:0005739)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0032806 carboxy-terminal domain protein kinase complex(GO:0032806)
0.0 1.1 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.1 GO:0033309 SBF transcription complex(GO:0033309)
0.0 0.2 GO:0033551 monopolin complex(GO:0033551)
0.0 0.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0000133 polarisome(GO:0000133)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784)
0.0 0.1 GO:0000417 HIR complex(GO:0000417)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 1.5 GO:0005815 microtubule organizing center(GO:0005815) spindle pole body(GO:0005816)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 1.3 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128) endocytic vesicle(GO:0030139) endocytic vesicle membrane(GO:0030666) clathrin-coated endocytic vesicle membrane(GO:0030669) clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.0 GO:0030907 MBF transcription complex(GO:0030907)
0.0 0.0 GO:0098562 side of membrane(GO:0098552) cytoplasmic side of membrane(GO:0098562)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.0 GO:0034990 mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990)
0.0 0.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 15.6 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
3.8 15.3 GO:0005537 mannose binding(GO:0005537)
3.2 16.1 GO:0015295 solute:proton symporter activity(GO:0015295)
1.8 7.2 GO:0004396 hexokinase activity(GO:0004396)
1.5 4.4 GO:0016406 carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406)
1.5 4.4 GO:0003843 1,3-beta-D-glucan synthase activity(GO:0003843)
1.2 4.8 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
1.2 2.3 GO:0015151 alpha-glucoside transmembrane transporter activity(GO:0015151) glucoside transmembrane transporter activity(GO:0042947)
1.1 4.6 GO:0015294 solute:cation symporter activity(GO:0015294)
1.1 8.6 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
1.1 7.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.0 5.0 GO:0008198 ferrous iron binding(GO:0008198)
1.0 2.9 GO:0048038 quinone binding(GO:0048038)
0.9 3.7 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.9 2.6 GO:0004564 beta-fructofuranosidase activity(GO:0004564) sucrose alpha-glucosidase activity(GO:0004575)
0.9 5.3 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.8 8.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.7 2.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.7 6.4 GO:0000149 SNARE binding(GO:0000149)
0.7 2.1 GO:0004555 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.7 2.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.7 2.7 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.7 3.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.6 1.9 GO:0008902 hydroxymethylpyrimidine kinase activity(GO:0008902) phosphomethylpyrimidine kinase activity(GO:0008972)
0.6 5.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.6 2.3 GO:0001097 TFIIH-class transcription factor binding(GO:0001097)
0.6 3.3 GO:0015293 symporter activity(GO:0015293)
0.5 2.2 GO:0015343 siderophore transmembrane transporter activity(GO:0015343) iron chelate transmembrane transporter activity(GO:0015603) siderophore transporter activity(GO:0042927)
0.5 3.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.5 9.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.5 5.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.5 3.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.5 1.5 GO:0005536 glucose binding(GO:0005536)
0.5 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.4 2.2 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.4 6.9 GO:0046906 heme binding(GO:0020037) tetrapyrrole binding(GO:0046906)
0.4 1.7 GO:0045118 azole transporter activity(GO:0045118)
0.4 5.5 GO:0015578 fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578)
0.4 1.9 GO:0018456 aryl-alcohol dehydrogenase (NAD+) activity(GO:0018456)
0.4 1.9 GO:0004075 biotin carboxylase activity(GO:0004075)
0.4 1.1 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.4 1.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.4 1.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.4 1.5 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.4 1.5 GO:0005186 mating pheromone activity(GO:0000772) pheromone activity(GO:0005186)
0.4 1.4 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.4 1.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.3 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 1.0 GO:0016878 AMP binding(GO:0016208) CoA-ligase activity(GO:0016405) acid-thiol ligase activity(GO:0016878)
0.3 16.2 GO:0001228 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3 1.3 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.3 1.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.3 1.6 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3 2.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 1.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 0.9 GO:0032183 SUMO binding(GO:0032183)
0.3 0.9 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.3 0.3 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.3 1.4 GO:0050253 triglyceride lipase activity(GO:0004806) retinyl-palmitate esterase activity(GO:0050253)
0.3 2.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.3 0.3 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.3 1.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.3 7.2 GO:0003684 damaged DNA binding(GO:0003684)
0.3 2.6 GO:0035064 methylated histone binding(GO:0035064)
0.3 4.9 GO:0019213 deacetylase activity(GO:0019213)
0.3 0.3 GO:0005261 cation channel activity(GO:0005261)
0.3 1.5 GO:0004030 aldehyde dehydrogenase (NAD) activity(GO:0004029) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2 1.0 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.2 1.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.2 0.9 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2 4.1 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.2 1.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 5.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 0.8 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.2 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 1.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.2 1.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 2.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.2 0.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 1.7 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.2 0.6 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.2 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 1.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 2.0 GO:0043495 protein anchor(GO:0043495)
0.2 0.7 GO:0016531 copper chaperone activity(GO:0016531)
0.2 0.9 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.2 1.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 2.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.2 1.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 0.5 GO:0004629 phospholipase C activity(GO:0004629)
0.2 1.3 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.2 1.4 GO:0000293 ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.2 2.0 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.2 1.1 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.4 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.1 GO:0031072 heat shock protein binding(GO:0031072)
0.1 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 1.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.9 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 1.5 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139) ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025) TFIIIC-class transcription factor binding(GO:0001156)
0.1 1.9 GO:0031491 nucleosome binding(GO:0031491)
0.1 1.7 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.1 1.4 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.3 GO:0001128 RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly(GO:0001128)
0.1 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.3 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 0.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 2.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 2.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 0.3 GO:0004100 chitin synthase activity(GO:0004100)
0.1 0.4 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.1 0.2 GO:0015489 putrescine transmembrane transporter activity(GO:0015489)
0.1 0.3 GO:0003954 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.1 0.1 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 1.0 GO:0045182 translation regulator activity(GO:0045182)
0.1 0.7 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.1 0.5 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.1 0.3 GO:0017022 myosin binding(GO:0017022)
0.1 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.5 GO:0001153 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) transcription factor activity, RNA polymerase III promoter sequence-specific binding, TFIIIB recruiting(GO:0001004) transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting(GO:0001005) transcription factor activity, RNA polymerase III type 2 promoter sequence-specific binding, TFIIIB recruiting(GO:0001008) RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034) transcription factor activity, RNA polymerase III transcription factor recruiting(GO:0001153) 5S rDNA binding(GO:0080084)
0.1 0.7 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.3 GO:0004180 carboxypeptidase activity(GO:0004180)
0.1 0.1 GO:0008106 aldo-keto reductase (NADP) activity(GO:0004033) alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 0.4 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.1 GO:0000150 recombinase activity(GO:0000150)
0.1 0.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.6 GO:0005507 copper ion binding(GO:0005507)
0.1 1.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.7 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 2.5 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 0.3 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.2 GO:0030414 endopeptidase inhibitor activity(GO:0004866) peptidase inhibitor activity(GO:0030414)
0.1 0.8 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.1 0.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.9 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0008897 holo-[acyl-carrier-protein] synthase activity(GO:0008897)
0.0 0.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.4 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 2.5 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.0 0.1 GO:0015085 calcium ion transmembrane transporter activity(GO:0015085)
0.0 0.2 GO:0004888 transmembrane signaling receptor activity(GO:0004888) signaling receptor activity(GO:0038023) transmembrane receptor activity(GO:0099600)
0.0 0.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.4 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.6 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.0 GO:0003951 NAD+ kinase activity(GO:0003951) NADH kinase activity(GO:0042736)
0.0 0.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.2 3.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.6 1.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.4 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.4 1.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.4 0.8 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 0.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 0.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 0.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 175.8 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
1.6 4.8 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.9 7.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 1.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.3 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.3 0.3 REACTOME LAGGING STRAND SYNTHESIS Genes involved in Lagging Strand Synthesis
0.2 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 2.3 REACTOME DNA REPAIR Genes involved in DNA Repair
0.1 0.1 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 0.8 REACTOME MEIOSIS Genes involved in Meiosis
0.1 174.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.1 REACTOME SIGNALING BY NOTCH Genes involved in Signaling by NOTCH
0.1 0.6 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.1 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.0 REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION Genes involved in Class I MHC mediated antigen processing & presentation