Results for REI1
Z-value: 1.34
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Transcription factors associated with REI1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
REI1
|
S000000471 | Cytoplasmic pre-60S factor |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YDR133C Show fit | 10.31 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C |
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| YNR001W-A Show fit | 9.11 |
Dubious open reading frame unlikely to encode a functional protein; identified by homology |
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| YFR055W Show fit | 8.59 |
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner |
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| YFR056C Show fit | 8.57 |
Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W |
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| YPL014W Show fit | 5.61 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus |
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| YGR249W Show fit | 5.37 |
Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants |
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| YBR126C Show fit | 5.27 |
Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway |
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| YOL086C Show fit | 5.18 |
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway |
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| YGL179C Show fit | 5.10 |
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome |
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| YIL162W Show fit | 4.94 |
Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively |
Network of associatons between targets according to the STRING database.
First level regulatory network of REI1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 11.8 | GO:0006757 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
| 0.1 | 9.8 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 1.3 | 9.2 | GO:0009312 | trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351) |
| 2.9 | 8.6 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.9 | 6.4 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501) |
| 1.5 | 6.2 | GO:0000296 | spermine transport(GO:0000296) |
| 0.3 | 5.9 | GO:0051029 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
| 1.3 | 5.1 | GO:0046513 | ceramide metabolic process(GO:0006672) ceramide biosynthetic process(GO:0046513) |
| 0.7 | 5.1 | GO:0019655 | glucose catabolic process(GO:0006007) glycolytic fermentation to ethanol(GO:0019655) glycolytic fermentation(GO:0019660) hexose catabolic process to ethanol(GO:1902707) |
| 1.7 | 5.0 | GO:0046466 | sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 22.3 | GO:0005576 | extracellular region(GO:0005576) |
| 0.1 | 11.9 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.1 | 11.2 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 8.8 | GO:0000139 | Golgi membrane(GO:0000139) |
| 2.1 | 8.6 | GO:0005946 | alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946) |
| 0.1 | 7.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 6.5 | GO:0009277 | fungal-type cell wall(GO:0009277) |
| 0.0 | 3.9 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 0.0 | 3.9 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 3.4 | GO:0005811 | lipid particle(GO:0005811) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 20.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 1.5 | 9.2 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 2.2 | 9.0 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 2.5 | 7.5 | GO:0003825 | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity(GO:0003825) |
| 0.5 | 6.6 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
| 1.1 | 6.5 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 1.5 | 6.2 | GO:0000297 | spermine transmembrane transporter activity(GO:0000297) |
| 1.4 | 5.8 | GO:0004396 | hexokinase activity(GO:0004396) |
| 1.6 | 4.9 | GO:0004564 | beta-fructofuranosidase activity(GO:0004564) sucrose alpha-glucosidase activity(GO:0004575) |
| 0.5 | 4.3 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 36.3 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 1.4 | 4.2 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.3 | 1.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.2 | 0.6 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 0.3 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.0 | 0.1 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.0 | PID LKB1 PATHWAY | LKB1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 38.5 | REACTOME GLYCOSAMINOGLYCAN METABOLISM | Genes involved in Glycosaminoglycan metabolism |
| 1.0 | 4.1 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 3.8 | REACTOME INFLUENZA LIFE CYCLE | Genes involved in Influenza Life Cycle |
| 0.3 | 2.2 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.7 | 2.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.7 | 2.1 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.4 | 1.4 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.2 | 1.1 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.1 | 0.7 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.2 | 0.6 | REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR | Genes involved in Downstream signaling of activated FGFR |