Results for NHP6B
Z-value: 0.64
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Transcription factors associated with NHP6B
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NHP6B
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S000002157 | High-mobility group (HMG) protein, binds to and remodels nucleosomes |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YPR169W-A Show fit | 2.10 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps two other dubious ORFs: YPR170C and YPR170W-B |
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| YKR034W Show fit | 1.90 |
Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p |
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| YHR126C Show fit | 1.11 |
Putative protein of unknown function; transcription dependent upon Azf1p |
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| YKR033C Show fit | 1.10 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene DAL80 |
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| YFL019C Show fit | 1.02 |
Dubious open reading frame unlikely to encode a protein; YFL019C is not an essential gene |
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| YMR107W Show fit | 1.01 |
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
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| YHR079C-A Show fit | 1.01 |
Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Mei5p; proposed to be an assembly factor for Dmc1p |
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| YKL221W Show fit | 0.99 |
Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport |
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| YBR292C Show fit | 0.97 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YBR292C is not an essential gene |
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| YPL026C Show fit | 0.92 |
Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway |
Network of associatons between targets according to the STRING database.
First level regulatory network of NHP6B
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.0 | GO:0090295 | nitrogen catabolite repression of transcription(GO:0090295) |
| 0.1 | 1.2 | GO:0070873 | regulation of glycogen biosynthetic process(GO:0005979) regulation of glycogen metabolic process(GO:0070873) |
| 0.2 | 1.0 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) DNA recombinase assembly(GO:0000730) |
| 0.1 | 0.9 | GO:0034284 | response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284) |
| 0.1 | 0.9 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.3 | 0.8 | GO:0051594 | detection of chemical stimulus(GO:0009593) detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) detection of stimulus(GO:0051606) |
| 0.2 | 0.8 | GO:0051099 | positive regulation of binding(GO:0051099) |
| 0.1 | 0.8 | GO:0000501 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 0.1 | 0.8 | GO:0000767 | cell morphogenesis involved in conjugation with cellular fusion(GO:0000753) cell morphogenesis involved in conjugation(GO:0000767) |
| 0.1 | 0.8 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.0 | 1.3 | GO:0042995 | mating projection(GO:0005937) cell projection(GO:0042995) |
| 0.2 | 0.9 | GO:0044462 | cell wall part(GO:0044426) external encapsulating structure part(GO:0044462) |
| 0.1 | 0.9 | GO:0034657 | GID complex(GO:0034657) |
| 0.1 | 0.9 | GO:0016586 | RSC complex(GO:0016586) |
| 0.1 | 0.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.8 | GO:0005628 | prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764) |
| 0.0 | 0.7 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.2 | 0.6 | GO:0031422 | RecQ helicase-Topo III complex(GO:0031422) |
| 0.1 | 0.6 | GO:0008180 | COP9 signalosome(GO:0008180) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.4 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 0.0 | 3.9 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.0 | 1.4 | GO:0000988 | transcription factor activity, protein binding(GO:0000988) |
| 0.1 | 1.3 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.3 | 1.2 | GO:0005186 | mating pheromone activity(GO:0000772) pheromone activity(GO:0005186) |
| 0.1 | 1.1 | GO:0019783 | ubiquitin-like protein-specific protease activity(GO:0019783) |
| 0.0 | 0.9 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.3 | 0.8 | GO:0005536 | glucose binding(GO:0005536) |
| 0.1 | 0.8 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.1 | 0.8 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 23.2 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.4 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 0.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 0.3 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.1 | 0.2 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.1 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.1 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.0 | 0.1 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.0 | PID FOXO PATHWAY | FoxO family signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 23.1 | REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.1 | 0.5 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 0.2 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.1 | 0.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 0.2 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 0.2 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.1 | 0.2 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.2 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 0.1 | 0.1 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.0 | 0.1 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |