Gene Symbol | Gene ID | Gene Info |
---|---|---|
MIG1
|
S000003003 | Transcription factor involved in glucose repression |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
YDR342C | 19.01 |
HXT7
|
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels |
|
YJL133C-A | 17.91 |
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
||
YGR067C | 17.62 |
Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p |
||
YDL210W | 15.41 |
UGA4
|
Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane |
|
YPR030W | 13.89 |
CSR2
|
Nuclear protein with a potential regulatory role in utilization of galactose and nonfermentable carbon sources; overproduction suppresses the lethality at high temperature of a chs5 spa2 double null mutation; potential Cdc28p substrate |
|
YFL052W | 13.20 |
Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity |
||
YIL162W | 13.03 |
SUC2
|
Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively |
|
YLR327C | 12.50 |
TMA10
|
Protein of unknown function that associates with ribosomes |
|
YAR035W | 12.32 |
YAT1
|
Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated |
|
YFR053C | 11.30 |
HXK1
|
Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p |
|
YIL057C | 11.15 |
Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose |
||
YPR184W | 9.90 |
GDB1
|
Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, required for glycogen degradation; phosphorylated in mitochondria |
|
YKL217W | 9.78 |
JEN1
|
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose |
|
YAL062W | 9.53 |
GDH3
|
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources |
|
YOR178C | 9.38 |
GAC1
|
Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock |
|
YNR073C | 8.62 |
Putative mannitol dehydrogenase |
||
YER084W | 8.25 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YDR277C | 8.16 |
MTH1
|
Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation |
|
YJR115W | 7.87 |
Putative protein of unknown function |
||
YOR100C | 7.78 |
CRC1
|
Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation |
|
YOR374W | 7.73 |
ALD4
|
Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed |
|
YDR059C | 7.52 |
UBC5
|
Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins, central component of the cellular stress response; expression is heat inducible |
|
YGR243W | 7.51 |
FMP43
|
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
|
YDL244W | 7.42 |
THI13
|
Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13 |
|
YOL052C-A | 7.15 |
DDR2
|
Multistress response protein, expression is activated by a variety of xenobiotic agents and environmental or physiological stresses |
|
YOR343C | 7.05 |
Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data |
||
YML089C | 6.83 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by calcium shortage |
||
YNR034W-A | 6.72 |
Putative protein of unknown function; expression is regulated by Msn2p/Msn4p |
||
YBR297W | 6.62 |
MAL33
|
MAL-activator protein, part of complex locus MAL3; nonfunctional in genomic reference strain S288C |
|
YDR536W | 6.43 |
STL1
|
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock |
|
YLR174W | 6.24 |
IDP2
|
Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose |
|
YOR383C | 6.07 |
FIT3
|
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
|
YNL052W | 5.79 |
COX5A
|
Subunit Va of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth |
|
YHR092C | 5.78 |
HXT4
|
High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose |
|
YOR393W | 5.67 |
ERR1
|
Protein of unknown function, has similarity to enolases |
|
YLR023C | 5.65 |
IZH3
|
Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity |
|
YJR095W | 5.60 |
SFC1
|
Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization |
|
YOR235W | 5.53 |
IRC13
|
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutant displays increased levels of spontaneous Rad52 foci |
|
YMR081C | 5.46 |
ISF1
|
Serine-rich, hydrophilic protein with similarity to Mbr1p; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant |
|
YPR150W | 5.41 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene SUE1/YPR151C |
||
YLR377C | 5.35 |
FBP1
|
Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism |
|
YCR091W | 5.23 |
KIN82
|
Putative serine/threonine protein kinase, most similar to cyclic nucleotide-dependent protein kinase subfamily and the protein kinase C subfamily |
|
YBR201C-A | 5.22 |
Putative protein of unknown function |
||
YBL048W | 5.18 |
Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data |
||
YFL051C | 5.16 |
Putative protein of unknown function; YFL051C is not an essential gene |
||
YGL062W | 5.12 |
PYC1
|
Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis |
|
YCL001W-B | 4.99 |
Putative protein of unknown function; identified by homology |
||
YDR216W | 4.87 |
ADR1
|
Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization |
|
YPR013C | 4.79 |
Putative zinc finger protein; YPR013C is not an essential gene |
||
YOL051W | 4.75 |
GAL11
|
Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors |
|
YLR149C | 4.68 |
Putative protein of unknown function; YLR149C is not an essential gene |
||
YOR065W | 4.65 |
CYT1
|
Cytochrome c1, component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex |
|
YPR010C-A | 4.55 |
Putative protein of unknown function; conserved among Saccharomyces sensu stricto species |
||
YEL011W | 4.54 |
GLC3
|
Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern |
|
YOR382W | 4.52 |
FIT2
|
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
|
YPL061W | 4.46 |
ALD6
|
Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress |
|
YGR043C | 4.45 |
NQM1
|
Protein of unknown function; transcription is repressed by Mot1p and induced by alpha-factor and during diauxic shift; null mutant non-quiescent cells exhibit reduced reproductive capacity |
|
YNL144C | 4.39 |
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YNL144C is not an essential gene |
||
YDL194W | 4.36 |
SNF3
|
Plasma membrane glucose sensor that regulates glucose transport; has 12 predicted transmembrane segments; long cytoplasmic C-terminal tail is required for low glucose induction of hexose transporter genes HXT2 and HXT4 |
|
YFL036W | 4.35 |
RPO41
|
Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; requires a specificity subunit encoded by MTF1 for promoter recognition |
|
YMR107W | 4.27 |
SPG4
|
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
|
YLR122C | 4.18 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR123C |
||
YDR018C | 4.15 |
Probable membrane protein with three predicted transmembrane domains; homologous to Ybr042cp, similar to C. elegans F55A11.5 and maize 1-acyl-glycerol-3-phosphate acyltransferase; null exhibits no apparent phenotype |
||
YCL054W | 4.14 |
SPB1
|
AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal subunit maturation; methylates G2922 in the tRNA docking site of the large subunit rRNA and in the absence of snR52, U2921; suppressor of PAB1 mutants |
|
YML090W | 4.13 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YML089C; exhibits growth defect on a non-fermentable (respiratory) carbon source |
||
YGR183C | 4.13 |
QCR9
|
Subunit 9 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex |
|
YPL024W | 4.09 |
RMI1
|
Involved in response to DNA damage; null mutants have increased rates of recombination and delayed S phase; interacts physically and genetically with Sgs1p (RecQ family member) and Top3p (topoisomerase III) |
|
YGL146C | 4.05 |
Putative protein of unknown function, contains two putative transmembrane spans, shows no significant homology to any other known protein sequence, YGL146C is not an essential gene |
||
YPR015C | 4.03 |
Putative protein of unknown function |
||
YBR051W | 3.98 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partiallly overlaps the REG2/YBR050C regulatory subunit of the Glc7p type-1 protein phosphatase |
||
YJL130C | 3.97 |
URA2
|
Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP |
|
YDR119W-A | 3.91 |
Putative protein of unknown function |
||
YDR178W | 3.90 |
SDH4
|
Membrane anchor subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone |
|
YBR050C | 3.90 |
REG2
|
Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease |
|
YPR005C | 3.87 |
HAL1
|
Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p |
|
YDL245C | 3.86 |
HXT15
|
Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose |
|
YEL049W | 3.82 |
PAU2
|
Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme |
|
YNL036W | 3.80 |
NCE103
|
Carbonic anhydrase; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; involved in non-classical protein export pathway |
|
YGR066C | 3.75 |
Putative protein of unknown function |
||
YHR033W | 3.73 |
Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm |
||
YKL093W | 3.71 |
MBR1
|
Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants |
|
YAL039C | 3.66 |
CYC3
|
Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS) |
|
YOR391C | 3.65 |
HSP33
|
Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp32p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease |
|
YPR065W | 3.59 |
ROX1
|
Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity |
|
YLR123C | 3.58 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR122C; contains characteristic aminoacyl-tRNA motif |
||
YER067W | 3.55 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YER067W is not an essential gene |
||
YKR102W | 3.52 |
FLO10
|
Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation |
|
YIL024C | 3.51 |
Putative protein of unknown function; non-essential gene; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p |
||
YML042W | 3.50 |
CAT2
|
Carnitine acetyl-CoA transferase present in both mitochondria and peroxisomes, transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes |
|
YPL026C | 3.49 |
SKS1
|
Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway |
|
YBR203W | 3.46 |
COS111
|
Protein required for resistance to the antifungal drug ciclopirox olamine; not related to the subtelomerically-encoded COS family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
|
YAL060W | 3.43 |
BDH1
|
NAD-dependent (R,R)-butanediol dehydrogenase, catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source |
|
YNL117W | 3.43 |
MLS1
|
Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth in oleic acid medium |
|
YJR151C | 3.41 |
DAN4
|
Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth |
|
YLR312C | 3.40 |
QNQ1
|
Protein of unknown function; null mutant quiescent and non-quiescent cells exhibit reduced reproductive capacity |
|
YGL033W | 3.38 |
HOP2
|
Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair |
|
YDR096W | 3.36 |
GIS1
|
JmjC domain-containing histone demethylase; transcription factor involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1 |
|
YBL064C | 3.28 |
PRX1
|
Mitochondrial peroxiredoxin (1-Cys Prx) with thioredoxin peroxidase activity, has a role in reduction of hydroperoxides; induced during respiratory growth and under conditions of oxidative stress; phosphorylated |
|
YML091C | 3.24 |
RPM2
|
Protein subunit of mitochondrial RNase P, has roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, and mitochondrial translation; distributed to mitochondria, cytoplasmic processing bodies, and the nucleus |
|
YAR050W | 3.22 |
FLO1
|
Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p |
|
YNL142W | 3.21 |
MEP2
|
Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation |
|
YDL079C | 3.21 |
MRK1
|
Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation |
|
YEL070W | 3.19 |
DSF1
|
Deletion suppressor of mpt5 mutation |
|
YHL021C | 3.17 |
AIM17
|
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) |
|
YER065C | 3.11 |
ICL1
|
Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose |
|
YHR211W | 3.05 |
FLO5
|
Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p |
|
YHL032C | 3.05 |
GUT1
|
Glycerol kinase, converts glycerol to glycerol-3-phosphate; glucose repression of expression is mediated by Adr1p and Ino2p-Ino4p; derepression of expression on non-fermentable carbon sources is mediated by Opi1p and Rsf1p |
|
YPL248C | 3.04 |
GAL4
|
DNA-binding transcription factor required for the activation of the GAL genes in response to galactose; repressed by Gal80p and activated by Gal3p |
|
YEL009C-A | 2.97 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YHR095W | 2.89 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YFR049W | 2.89 |
YMR31
|
Mitochondrial ribosomal protein of the small subunit, has similarity to human mitochondrial ribosomal protein MRP-S36 |
|
YJL116C | 2.88 |
NCA3
|
Protein that functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p ) of the Fo-F1 ATP synthase; member of the SUN family |
|
YER121W | 2.88 |
Putative protein of unknown function; may be involved in phosphatase regulation and/or generation of precursor metabolites and energy |
||
YEL008W | 2.85 |
Hypothetical protein predicted to be involved in metabolism |
||
YDL169C | 2.85 |
UGX2
|
Protein of unknown function, transcript accumulates in response to any combination of stress conditions |
|
YLR142W | 2.83 |
PUT1
|
Proline oxidase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; PUT1 transcription is induced by Put3p in the presence of proline and the absence of a preferred nitrogen source |
|
YOR152C | 2.82 |
Putative protein of unknown function; has no similarity to any known protein; YOR152C is not an essential gene |
||
YEL009C | 2.81 |
GCN4
|
Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels |
|
YNL018C | 2.78 |
Putative protein of unknown function |
||
YCR010C | 2.77 |
ADY2
|
Acetate transporter required for normal sporulation; phosphorylated in mitochondria |
|
YGL180W | 2.74 |
ATG1
|
Protein serine/threonine kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for pre-autophagosome formation; during autophagy forms a complex with Atg13p and Atg17p |
|
YGR258C | 2.74 |
RAD2
|
Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein |
|
YKL163W | 2.74 |
PIR3
|
O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway |
|
YMR105C | 2.72 |
PGM2
|
Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase |
|
YER150W | 2.69 |
SPI1
|
GPI-anchored cell wall protein involved in weak acid resistance; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; similar to Sed1p |
|
YAL063C | 2.67 |
FLO9
|
Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation |
|
YBR033W | 2.66 |
EDS1
|
Putative zinc cluster protein; YBR033W is not an essential gene |
|
YLR124W | 2.65 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YGL163C | 2.62 |
RAD54
|
DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family |
|
YJR160C | 2.58 |
MPH3
|
Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph2p; encoded in a subtelomeric position in a region likely to have undergone duplication |
|
YOL081W | 2.57 |
IRA2
|
GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin |
|
YPR002W | 2.56 |
PDH1
|
Mitochondrial protein that participates in respiration, induced by diauxic shift; homologous to E. coli PrpD, may take part in the conversion of 2-methylcitrate to 2-methylisocitrate |
|
YMR194C-B | 2.56 |
Putative protein of unknown function |
||
YAR047C | 2.54 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YNR002C | 2.49 |
ATO2
|
Putative transmembrane protein involved in export of ammonia, a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Ady2p and Y. lipolytica Gpr1p |
|
YBL015W | 2.46 |
ACH1
|
Acetyl-coA hydrolase, primarily localized to mitochondria; phosphorylated; required for acetate utilization and for diploid pseudohyphal growth |
|
YKL031W | 2.45 |
Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species |
||
YLR273C | 2.42 |
PIG1
|
Putative targeting subunit for the type-1 protein phosphatase Glc7p that tethers it to the Gsy2p glycogen synthase |
|
YCL025C | 2.40 |
AGP1
|
Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p) |
|
YOR328W | 2.38 |
PDR10
|
ATP-binding cassette (ABC) transporter, multidrug transporter involved in the pleiotropic drug resistance network; regulated by Pdr1p and Pdr3p |
|
YLR279W | 2.35 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YOL082W | 2.35 |
ATG19
|
Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway; recognizes cargo proteins aminopeptidase I (Lap4p) and alpha-mannosidase (Ams1p) and delivers them to the preautophagosomal structure for packaging into Cvt vesicles |
|
YJL045W | 2.34 |
Minor succinate dehydrogenase isozyme; homologous to Sdh1p, the major isozyme reponsible for the oxidation of succinate and transfer of electrons to ubiquinone; induced during the diauxic shift in a Cat8p-dependent manner |
||
YKL109W | 2.32 |
HAP4
|
Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex |
|
YPR151C | 2.31 |
SUE1
|
Mitochondrial protein required for degradation of unstable forms of cytochrome c |
|
YGR023W | 2.31 |
MTL1
|
Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone-induced morphogenesis; suppresses rgd1 null mutations |
|
YNL077W | 2.28 |
APJ1
|
Putative chaperone of the HSP40 (DNAJ) family; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
|
YLR393W | 2.27 |
ATP10
|
Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, interacts genetically with ATP6 |
|
YJR121W | 2.25 |
ATP2
|
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated |
|
YDR343C | 2.22 |
HXT6
|
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3 |
|
YPR006C | 2.21 |
ICL2
|
2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol |
|
YBR132C | 2.20 |
AGP2
|
High affinity polyamine permease, preferentially uses spermidine over putrescine; expression is down-regulated by osmotic stress; plasma membrane carnitine transporter, also functions as a low-affinity amino acid permease |
|
YGR022C | 2.19 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF MTL1/YGR023W |
||
YEL012W | 2.19 |
UBC8
|
Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro |
|
YLR037C | 2.17 |
DAN2
|
Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth |
|
YEL010W | 2.16 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YNL143C | 2.13 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YJL199C | 2.12 |
MBB1
|
Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; protein detected in large-scale protein-protein interaction studies |
|
YPL186C | 2.12 |
UIP4
|
Protein that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates; detected in a phosphorylated state in the mitochondrial outer membrane; also detected in ER and nuclear envelope |
|
YFL011W | 2.12 |
HXT10
|
Putative hexose transporter, expressed at low levels and expression is repressed by glucose |
|
YBR105C | 2.11 |
VID24
|
Peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulates fructose-1,6-bisphosphatase (FBPase) targeting to the vacuole; involved in proteasome-dependent catabolite degradation of FBPase |
|
YOR245C | 2.11 |
DGA1
|
Diacylglycerol acyltransferase, catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor, localized to lipid particles |
|
YPL089C | 2.10 |
RLM1
|
MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p |
|
YFL055W | 2.09 |
AGP3
|
Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation; plays a role in regulating Ty1 transposition |
|
YDR034C | 2.06 |
LYS14
|
Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer |
|
YOR120W | 2.06 |
GCY1
|
Putative NADP(+) coupled glycerol dehydrogenase, proposed to be involved in an alternative pathway for glycerol catabolism; member of the aldo-keto reductase (AKR) family |
|
YLR125W | 2.06 |
Putative protein of unknown function; mutant has decreased Ty3 transposition; YLR125W is not an essential gene |
||
YJL100W | 2.05 |
LSB6
|
Type II phosphatidylinositol 4-kinase that binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization |
|
YDR085C | 2.04 |
AFR1
|
Alpha-factor pheromone receptor regulator, negatively regulates pheromone receptor signaling; required for normal mating projection (shmoo) formation; required for Spa2p to recruit Mpk1p to shmoo tip during mating; interacts with Cdc12p |
|
YCR073W-A | 2.02 |
SOL2
|
Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol1p, Sol3p, and Sol4p |
|
YDL214C | 2.00 |
PRR2
|
Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor |
|
YOR394W | 2.00 |
PAU21
|
Hypothetical protein |
|
YMR017W | 1.99 |
SPO20
|
Meiosis-specific subunit of the t-SNARE complex, required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; SNAP-25 homolog |
|
YDR441C | 1.98 |
APT2
|
Apparent pseudogene, not transcribed or translated under normal conditions; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity |
|
YOR236W | 1.96 |
DFR1
|
Dihydrofolate reductase, part of the dTTP biosynthetic pathway, involved in folate metabolism, possibly required for mitochondrial function |
|
YNL037C | 1.94 |
IDH1
|
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle |
|
YAL067C | 1.94 |
SEO1
|
Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide |
|
YBL045C | 1.91 |
COR1
|
Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of the mitochondrial inner membrane electron transport chain |
|
YOR392W | 1.90 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; gene expression induced by heat |
||
YPL230W | 1.89 |
USV1
|
Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in protein folding, ATP binding, and cell wall biosynthesis |
|
YFL019C | 1.89 |
Dubious open reading frame unlikely to encode a protein; YFL019C is not an essential gene |
||
YOR376W | 1.89 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YOR376W is not an essential gene. |
||
YFR017C | 1.88 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YFR017C is not an essential gene |
||
YDR043C | 1.86 |
NRG1
|
Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response |
|
YER187W | 1.86 |
Putative protein of unknown function; induced in respiratory-deficient cells |
||
YPL185W | 1.86 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene UIP4/YPL186C |
||
YLL039C | 1.85 |
UBI4
|
Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats |
|
YOR388C | 1.85 |
FDH1
|
NAD(+)-dependent formate dehydrogenase, may protect cells from exogenous formate |
|
YIR027C | 1.84 |
DAL1
|
Allantoinase, converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression |
|
YIL060W | 1.84 |
Putative protein of unknown function; mutant accumulates less glycogen than does wild type; YIL060W is not an essential gene |
||
YPR196W | 1.83 |
Putative maltose activator |
||
YPL282C | 1.81 |
PAU22
|
Hypothetical protein |
|
YPR049C | 1.80 |
ATG11
|
Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; directs receptor-bound cargo to the pro-autophagosomal structure (PAS) for packaging into vesicles; required for recruiting other proteins to the PAS |
|
YFL054C | 1.79 |
Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol |
||
YHR080C | 1.78 |
Protein of unknown function that may interact with ribosomes, based on co-purification experiments; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
||
YFL034W | 1.77 |
Putative integral membrane protein that interacts with Rpp0p, which is a component of the ribosomal stalk |
||
YER014C-A | 1.76 |
BUD25
|
Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern |
|
YKL168C | 1.76 |
KKQ8
|
Putative serine/threonine protein kinase with unknown cellular role |
|
YKL188C | 1.75 |
PXA2
|
Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins |
|
YMR104C | 1.75 |
YPK2
|
Protein kinase with similarityto serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.3 | 15.8 | GO:0009437 | amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437) |
4.9 | 4.9 | GO:0034310 | ethanol catabolic process(GO:0006068) primary alcohol catabolic process(GO:0034310) |
4.4 | 13.1 | GO:0015755 | fructose transport(GO:0015755) |
4.2 | 16.7 | GO:0015847 | putrescine transport(GO:0015847) |
4.1 | 12.2 | GO:0019413 | acetate biosynthetic process(GO:0019413) |
3.7 | 14.9 | GO:0006848 | pyruvate transport(GO:0006848) |
2.4 | 12.1 | GO:0005980 | glycogen catabolic process(GO:0005980) |
2.2 | 13.0 | GO:0005985 | sucrose metabolic process(GO:0005985) sucrose catabolic process(GO:0005987) |
2.1 | 12.8 | GO:0000128 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
2.1 | 14.6 | GO:0000023 | maltose metabolic process(GO:0000023) |
1.9 | 5.7 | GO:0019543 | propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) short-chain fatty acid catabolic process(GO:0019626) propionate catabolic process, 2-methylcitrate cycle(GO:0019629) |
1.7 | 5.1 | GO:0015740 | C4-dicarboxylate transport(GO:0015740) |
1.7 | 5.0 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
1.6 | 8.2 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
1.6 | 14.1 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
1.6 | 4.7 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
1.4 | 4.3 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
1.3 | 10.5 | GO:0015891 | siderophore transport(GO:0015891) |
1.3 | 7.6 | GO:0006097 | glyoxylate cycle(GO:0006097) |
1.2 | 21.2 | GO:0005978 | glycogen biosynthetic process(GO:0005978) |
1.2 | 3.7 | GO:0017006 | protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063) |
1.2 | 4.8 | GO:0015976 | carbon utilization(GO:0015976) |
1.1 | 3.2 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
1.0 | 4.2 | GO:0019405 | alditol catabolic process(GO:0019405) glycerol catabolic process(GO:0019563) |
1.0 | 4.1 | GO:0051101 | positive regulation of DNA binding(GO:0043388) regulation of DNA binding(GO:0051101) |
1.0 | 10.0 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
1.0 | 4.8 | GO:0015793 | glycerol transport(GO:0015793) |
0.9 | 2.8 | GO:0010133 | proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133) |
0.9 | 6.6 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
0.9 | 3.7 | GO:0009190 | cAMP biosynthetic process(GO:0006171) cyclic nucleotide biosynthetic process(GO:0009190) cyclic purine nucleotide metabolic process(GO:0052652) |
0.8 | 3.3 | GO:0008214 | protein demethylation(GO:0006482) protein dealkylation(GO:0008214) histone demethylation(GO:0016577) demethylation(GO:0070988) |
0.8 | 3.3 | GO:0010688 | negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter(GO:0010688) |
0.8 | 3.9 | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone(GO:0006121) |
0.8 | 3.1 | GO:0000435 | regulation of transcription from RNA polymerase II promoter by galactose(GO:0000431) positive regulation of transcription from RNA polymerase II promoter by galactose(GO:0000435) |
0.7 | 0.7 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
0.7 | 2.1 | GO:0051469 | vesicle fusion with vacuole(GO:0051469) |
0.7 | 2.1 | GO:0042843 | D-xylose catabolic process(GO:0042843) |
0.7 | 2.1 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
0.7 | 6.1 | GO:0045332 | phospholipid translocation(GO:0045332) |
0.7 | 2.0 | GO:0044209 | AMP salvage(GO:0044209) |
0.7 | 3.3 | GO:0032070 | regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071) |
0.6 | 1.9 | GO:1900460 | negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter(GO:1900460) |
0.6 | 6.0 | GO:0009065 | glutamine family amino acid catabolic process(GO:0009065) |
0.6 | 5.7 | GO:0009743 | response to carbohydrate(GO:0009743) |
0.6 | 5.7 | GO:0055069 | cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069) |
0.6 | 9.5 | GO:0042724 | thiamine biosynthetic process(GO:0009228) thiamine-containing compound biosynthetic process(GO:0042724) |
0.6 | 2.2 | GO:0006083 | acetate metabolic process(GO:0006083) |
0.5 | 2.7 | GO:0033683 | nucleotide-excision repair, DNA incision(GO:0033683) |
0.5 | 1.6 | GO:0033499 | galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499) |
0.5 | 4.8 | GO:0000436 | carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) |
0.5 | 4.1 | GO:0031167 | rRNA methylation(GO:0031167) |
0.5 | 5.1 | GO:0046686 | response to cadmium ion(GO:0046686) |
0.5 | 2.0 | GO:0031135 | negative regulation of conjugation(GO:0031135) negative regulation of conjugation with cellular fusion(GO:0031138) negative regulation of multi-organism process(GO:0043901) |
0.5 | 1.0 | GO:0090295 | nitrogen catabolite repression of transcription(GO:0090295) |
0.5 | 0.5 | GO:1904951 | positive regulation of protein transport(GO:0051222) positive regulation of establishment of protein localization(GO:1904951) |
0.5 | 1.5 | GO:0071050 | snoRNA polyadenylation(GO:0071050) |
0.5 | 9.6 | GO:0000209 | protein polyubiquitination(GO:0000209) |
0.5 | 1.4 | GO:0015888 | thiamine transport(GO:0015888) |
0.5 | 1.8 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.4 | 1.8 | GO:2000284 | positive regulation of cellular amino acid biosynthetic process(GO:2000284) |
0.4 | 0.9 | GO:0008272 | sulfate transport(GO:0008272) |
0.4 | 1.3 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
0.4 | 6.0 | GO:0015718 | monocarboxylic acid transport(GO:0015718) |
0.4 | 2.1 | GO:0006071 | glycerol metabolic process(GO:0006071) alditol metabolic process(GO:0019400) |
0.4 | 1.2 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
0.4 | 2.4 | GO:0000256 | allantoin metabolic process(GO:0000255) allantoin catabolic process(GO:0000256) |
0.4 | 5.1 | GO:0046173 | polyol biosynthetic process(GO:0046173) |
0.4 | 3.8 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) proton-transporting ATP synthase complex assembly(GO:0043461) |
0.4 | 1.5 | GO:0006078 | (1->6)-beta-D-glucan biosynthetic process(GO:0006078) |
0.4 | 1.1 | GO:0008216 | spermidine metabolic process(GO:0008216) |
0.4 | 1.4 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
0.4 | 1.4 | GO:0090294 | nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) nitrogen catabolite activation of transcription(GO:0090294) |
0.3 | 4.3 | GO:0072593 | reactive oxygen species metabolic process(GO:0072593) |
0.3 | 2.0 | GO:0006089 | lactate metabolic process(GO:0006089) |
0.3 | 0.7 | GO:1905038 | regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) regulation of membrane lipid metabolic process(GO:1905038) |
0.3 | 1.3 | GO:0015886 | heme transport(GO:0015886) |
0.3 | 0.6 | GO:0042775 | respiratory electron transport chain(GO:0022904) ATP synthesis coupled electron transport(GO:0042773) mitochondrial ATP synthesis coupled electron transport(GO:0042775) |
0.3 | 3.3 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.3 | 1.2 | GO:0035968 | positive regulation of lipid transport(GO:0032370) regulation of sterol transport(GO:0032371) positive regulation of sterol transport(GO:0032373) positive regulation of transmembrane transport(GO:0034764) regulation of sterol import by regulation of transcription from RNA polymerase II promoter(GO:0035968) positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter(GO:0035969) regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) regulation of sterol import(GO:2000909) positive regulation of sterol import(GO:2000911) |
0.3 | 2.9 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
0.3 | 0.6 | GO:0046185 | aldehyde catabolic process(GO:0046185) |
0.3 | 2.5 | GO:0008277 | regulation of G-protein coupled receptor protein signaling pathway(GO:0008277) |
0.3 | 0.8 | GO:0000101 | sulfur amino acid transport(GO:0000101) |
0.3 | 1.9 | GO:0097034 | mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
0.3 | 0.8 | GO:0001113 | transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) |
0.3 | 0.3 | GO:0010993 | regulation of ubiquitin homeostasis(GO:0010993) |
0.2 | 0.5 | GO:0006537 | glutamate metabolic process(GO:0006536) glutamate biosynthetic process(GO:0006537) |
0.2 | 0.2 | GO:0008615 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819) |
0.2 | 9.6 | GO:0009060 | aerobic respiration(GO:0009060) |
0.2 | 2.4 | GO:1905037 | autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037) |
0.2 | 3.9 | GO:0007129 | synapsis(GO:0007129) |
0.2 | 0.8 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) manganese ion homeostasis(GO:0055071) |
0.2 | 2.8 | GO:0006757 | glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757) |
0.2 | 1.2 | GO:0009164 | nucleoside catabolic process(GO:0009164) glycosyl compound catabolic process(GO:1901658) |
0.2 | 1.2 | GO:0015851 | nucleobase transport(GO:0015851) |
0.2 | 2.6 | GO:0031321 | ascospore-type prospore assembly(GO:0031321) |
0.2 | 0.9 | GO:0031507 | heterochromatin assembly(GO:0031507) |
0.2 | 3.2 | GO:0051156 | glucose 6-phosphate metabolic process(GO:0051156) |
0.2 | 0.9 | GO:0032973 | amino acid export(GO:0032973) amino acid transmembrane export from vacuole(GO:0032974) vacuolar transmembrane transport(GO:0034486) vacuolar amino acid transmembrane transport(GO:0034487) amino acid transmembrane export(GO:0044746) |
0.2 | 0.2 | GO:1901678 | iron coordination entity transport(GO:1901678) |
0.2 | 0.5 | GO:1902751 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751) |
0.2 | 0.9 | GO:0070941 | eisosome assembly(GO:0070941) |
0.2 | 3.0 | GO:0015749 | hexose transport(GO:0008645) monosaccharide transport(GO:0015749) |
0.2 | 0.5 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
0.2 | 0.8 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
0.2 | 0.2 | GO:0006824 | cobalt ion transport(GO:0006824) |
0.2 | 0.6 | GO:0006075 | (1->3)-beta-D-glucan biosynthetic process(GO:0006075) |
0.1 | 1.0 | GO:0045740 | positive regulation of DNA replication(GO:0045740) |
0.1 | 1.6 | GO:0046854 | lipid phosphorylation(GO:0046834) phosphatidylinositol phosphorylation(GO:0046854) |
0.1 | 1.2 | GO:0019878 | lysine biosynthetic process via aminoadipic acid(GO:0019878) |
0.1 | 0.4 | GO:0071281 | response to iron ion(GO:0010039) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) cellular response to iron ion(GO:0071281) |
0.1 | 0.5 | GO:0030969 | mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) IRE1-mediated unfolded protein response(GO:0036498) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054) |
0.1 | 0.4 | GO:0000751 | mitotic cell cycle arrest in response to pheromone(GO:0000751) mitotic cell cycle arrest(GO:0071850) |
0.1 | 0.4 | GO:0071456 | cellular response to hypoxia(GO:0071456) |
0.1 | 4.8 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
0.1 | 2.8 | GO:0007266 | Rho protein signal transduction(GO:0007266) |
0.1 | 0.6 | GO:0008053 | mitochondrial fusion(GO:0008053) |
0.1 | 0.5 | GO:0060237 | regulation of fungal-type cell wall organization(GO:0060237) |
0.1 | 1.3 | GO:0016925 | protein sumoylation(GO:0016925) |
0.1 | 0.6 | GO:0070900 | mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864) |
0.1 | 0.6 | GO:0070124 | mitochondrial translational initiation(GO:0070124) |
0.1 | 1.6 | GO:0000422 | mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726) |
0.1 | 0.4 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
0.1 | 2.3 | GO:0022900 | electron transport chain(GO:0022900) |
0.1 | 0.2 | GO:0051098 | regulation of binding(GO:0051098) |
0.1 | 1.9 | GO:0031503 | protein complex localization(GO:0031503) |
0.1 | 0.3 | GO:0032006 | regulation of TOR signaling(GO:0032006) |
0.1 | 0.2 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.1 | 0.3 | GO:0032056 | positive regulation of translation in response to stress(GO:0032056) |
0.1 | 0.2 | GO:0045861 | negative regulation of proteolysis(GO:0045861) |
0.1 | 0.9 | GO:0006826 | iron ion transport(GO:0006826) |
0.1 | 1.6 | GO:0001101 | response to acid chemical(GO:0001101) |
0.1 | 0.6 | GO:0046020 | negative regulation of transcription by pheromones(GO:0045996) negative regulation of transcription from RNA polymerase II promoter by pheromones(GO:0046020) |
0.1 | 0.6 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.1 | 0.8 | GO:0051181 | cofactor transport(GO:0051181) |
0.1 | 0.4 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.1 | 0.3 | GO:0070304 | positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304) |
0.1 | 0.6 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.1 | 1.0 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
0.1 | 1.6 | GO:0006094 | gluconeogenesis(GO:0006094) |
0.1 | 0.4 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.1 | 0.2 | GO:0052547 | negative regulation of peptidase activity(GO:0010466) regulation of peptidase activity(GO:0052547) |
0.1 | 0.5 | GO:0045003 | double-strand break repair via synthesis-dependent strand annealing(GO:0045003) |
0.1 | 0.8 | GO:0006081 | cellular aldehyde metabolic process(GO:0006081) |
0.1 | 0.1 | GO:2000058 | regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058) |
0.1 | 0.3 | GO:0032581 | ER-dependent peroxisome organization(GO:0032581) |
0.1 | 1.3 | GO:0016579 | protein deubiquitination(GO:0016579) |
0.1 | 0.2 | GO:0001308 | negative regulation of chromatin silencing involved in replicative cell aging(GO:0001308) |
0.1 | 0.3 | GO:0046341 | CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341) |
0.1 | 0.4 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
0.1 | 0.4 | GO:0006452 | translational frameshifting(GO:0006452) |
0.1 | 0.3 | GO:0046931 | pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292) |
0.1 | 0.2 | GO:0032979 | protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) |
0.1 | 0.6 | GO:0009092 | homoserine metabolic process(GO:0009092) |
0.1 | 0.1 | GO:0001323 | age-dependent general metabolic decline involved in chronological cell aging(GO:0001323) age-dependent response to oxidative stress involved in chronological cell aging(GO:0001324) |
0.1 | 0.2 | GO:0051260 | protein homooligomerization(GO:0051260) |
0.1 | 0.2 | GO:0034090 | maintenance of meiotic sister chromatid cohesion(GO:0034090) |
0.1 | 0.2 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
0.1 | 0.2 | GO:0055088 | lipid homeostasis(GO:0055088) |
0.1 | 0.3 | GO:0034354 | 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627) |
0.1 | 0.1 | GO:0051204 | protein insertion into mitochondrial membrane(GO:0051204) |
0.1 | 0.6 | GO:0009968 | negative regulation of signal transduction(GO:0009968) negative regulation of signaling(GO:0023057) |
0.1 | 0.3 | GO:0006744 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) ketone biosynthetic process(GO:0042181) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663) |
0.1 | 0.4 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
0.0 | 0.2 | GO:0000196 | MAPK cascade involved in cell wall organization or biogenesis(GO:0000196) |
0.0 | 0.6 | GO:0072329 | monocarboxylic acid catabolic process(GO:0072329) |
0.0 | 0.2 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
0.0 | 0.1 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 0.1 | GO:0000709 | meiotic joint molecule formation(GO:0000709) |
0.0 | 1.5 | GO:0042176 | regulation of protein catabolic process(GO:0042176) |
0.0 | 0.2 | GO:0000338 | protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388) |
0.0 | 1.5 | GO:0070591 | ascospore wall assembly(GO:0030476) spore wall assembly(GO:0042244) spore wall biogenesis(GO:0070590) ascospore wall biogenesis(GO:0070591) fungal-type cell wall assembly(GO:0071940) |
0.0 | 0.7 | GO:0036003 | positive regulation of transcription from RNA polymerase II promoter in response to stress(GO:0036003) |
0.0 | 0.1 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.0 | 0.4 | GO:0015893 | drug transport(GO:0015893) |
0.0 | 0.4 | GO:0045910 | negative regulation of DNA recombination(GO:0045910) |
0.0 | 0.3 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
0.0 | 0.3 | GO:0045143 | homologous chromosome segregation(GO:0045143) |
0.0 | 0.5 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
0.0 | 0.2 | GO:0000161 | MAPK cascade involved in osmosensory signaling pathway(GO:0000161) |
0.0 | 0.5 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
0.0 | 0.2 | GO:0051598 | meiotic cell cycle checkpoint(GO:0033313) meiotic recombination checkpoint(GO:0051598) |
0.0 | 0.1 | GO:0030100 | regulation of endocytosis(GO:0030100) |
0.0 | 0.1 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
0.0 | 0.1 | GO:0000390 | spliceosomal complex disassembly(GO:0000390) |
0.0 | 0.3 | GO:0042493 | response to drug(GO:0042493) |
0.0 | 0.2 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
0.0 | 0.0 | GO:0045117 | azole transport(GO:0045117) |
0.0 | 0.1 | GO:0009410 | response to xenobiotic stimulus(GO:0009410) |
0.0 | 0.3 | GO:0006312 | mitotic recombination(GO:0006312) |
0.0 | 0.1 | GO:0030835 | regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) barbed-end actin filament capping(GO:0051016) actin filament capping(GO:0051693) |
0.0 | 0.1 | GO:0000114 | obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114) |
0.0 | 0.0 | GO:0006085 | acetyl-CoA biosynthetic process(GO:0006085) acetyl-CoA biosynthetic process from pyruvate(GO:0006086) |
0.0 | 0.2 | GO:0006272 | leading strand elongation(GO:0006272) |
0.0 | 0.1 | GO:0030149 | sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466) |
0.0 | 0.1 | GO:0019932 | second-messenger-mediated signaling(GO:0019932) |
0.0 | 0.2 | GO:0000349 | generation of catalytic spliceosome for first transesterification step(GO:0000349) |
0.0 | 0.3 | GO:0048278 | vesicle docking(GO:0048278) |
0.0 | 0.2 | GO:0006284 | base-excision repair(GO:0006284) |
0.0 | 0.1 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
0.0 | 0.2 | GO:0006749 | glutathione metabolic process(GO:0006749) |
0.0 | 0.0 | GO:0042173 | regulation of sporulation resulting in formation of a cellular spore(GO:0042173) |
0.0 | 0.2 | GO:0007020 | microtubule nucleation(GO:0007020) |
0.0 | 0.0 | GO:0035822 | meiotic gene conversion(GO:0006311) gene conversion(GO:0035822) |
0.0 | 0.1 | GO:0000753 | cell morphogenesis involved in conjugation with cellular fusion(GO:0000753) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.0 | 16.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
1.4 | 4.1 | GO:0031422 | RecQ helicase-Topo III complex(GO:0031422) |
1.2 | 11.1 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
0.9 | 2.8 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.9 | 2.7 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.8 | 7.6 | GO:0070069 | cytochrome complex(GO:0070069) |
0.8 | 3.9 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) respiratory chain complex(GO:0098803) |
0.7 | 2.9 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.7 | 3.3 | GO:0000275 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.7 | 3.3 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
0.6 | 2.6 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
0.6 | 2.5 | GO:0070469 | respiratory chain(GO:0070469) |
0.6 | 12.8 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
0.5 | 3.6 | GO:0042597 | periplasmic space(GO:0042597) |
0.4 | 21.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.4 | 2.7 | GO:0000112 | nucleotide-excision repair factor 3 complex(GO:0000112) |
0.4 | 4.6 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
0.3 | 1.7 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.3 | 1.7 | GO:0001400 | mating projection base(GO:0001400) |
0.3 | 2.3 | GO:0034657 | GID complex(GO:0034657) |
0.3 | 2.9 | GO:0030677 | ribonuclease P complex(GO:0030677) |
0.3 | 3.1 | GO:0005619 | ascospore wall(GO:0005619) |
0.3 | 0.8 | GO:0030870 | Mre11 complex(GO:0030870) |
0.3 | 12.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.3 | 40.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
0.3 | 5.1 | GO:0070847 | core mediator complex(GO:0070847) |
0.2 | 8.3 | GO:0005576 | extracellular region(GO:0005576) |
0.2 | 2.9 | GO:0031307 | intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307) |
0.2 | 0.4 | GO:0000111 | nucleotide-excision repair factor 2 complex(GO:0000111) |
0.2 | 0.9 | GO:0033100 | NuA3 histone acetyltransferase complex(GO:0033100) H3 histone acetyltransferase complex(GO:0070775) |
0.2 | 1.0 | GO:0009277 | fungal-type cell wall(GO:0009277) |
0.2 | 1.3 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.1 | 0.6 | GO:0000148 | 1,3-beta-D-glucan synthase complex(GO:0000148) |
0.1 | 0.8 | GO:0033263 | CORVET complex(GO:0033263) |
0.1 | 2.6 | GO:0005811 | lipid particle(GO:0005811) |
0.1 | 0.2 | GO:0070985 | TFIIK complex(GO:0070985) |
0.1 | 1.7 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
0.1 | 1.4 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.1 | 0.7 | GO:0035339 | serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339) |
0.1 | 16.3 | GO:0000324 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
0.1 | 1.4 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.1 | 69.7 | GO:0005739 | mitochondrion(GO:0005739) |
0.1 | 5.2 | GO:0000502 | proteasome complex(GO:0000502) |
0.1 | 0.4 | GO:0008623 | CHRAC(GO:0008623) |
0.1 | 0.6 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.1 | 0.3 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
0.1 | 0.5 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.1 | 1.4 | GO:0005628 | prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764) |
0.1 | 0.9 | GO:0000812 | Swr1 complex(GO:0000812) |
0.1 | 0.2 | GO:0000126 | transcription factor TFIIIB complex(GO:0000126) |
0.1 | 0.3 | GO:0033551 | monopolin complex(GO:0033551) |
0.1 | 0.4 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.1 | 0.2 | GO:0033186 | CAF-1 complex(GO:0033186) |
0.1 | 0.2 | GO:0000113 | nucleotide-excision repair factor 4 complex(GO:0000113) |
0.0 | 0.2 | GO:0033309 | SBF transcription complex(GO:0033309) |
0.0 | 0.2 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.2 | GO:0033101 | cellular bud membrane(GO:0033101) |
0.0 | 0.5 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
0.0 | 0.2 | GO:0031391 | Elg1 RFC-like complex(GO:0031391) |
0.0 | 0.3 | GO:0034967 | Set3 complex(GO:0034967) |
0.0 | 0.5 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827) |
0.0 | 0.1 | GO:0005884 | actin filament(GO:0005884) |
0.0 | 0.2 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012) |
0.0 | 0.2 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
0.0 | 0.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) condensed nuclear chromosome outer kinetochore(GO:0000942) |
0.0 | 0.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
6.7 | 33.4 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
5.3 | 15.8 | GO:0016406 | carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406) |
4.7 | 14.2 | GO:0004575 | beta-fructofuranosidase activity(GO:0004564) sucrose alpha-glucosidase activity(GO:0004575) |
3.3 | 9.9 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
3.1 | 12.5 | GO:0005537 | mannose binding(GO:0005537) |
2.4 | 9.7 | GO:0004396 | hexokinase activity(GO:0004396) |
2.1 | 6.2 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
2.0 | 12.2 | GO:0004030 | aldehyde dehydrogenase (NAD) activity(GO:0004029) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
1.7 | 3.5 | GO:0042947 | alpha-glucoside transmembrane transporter activity(GO:0015151) glucoside transmembrane transporter activity(GO:0042947) |
1.7 | 5.1 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
1.6 | 4.8 | GO:0005536 | glucose binding(GO:0005536) |
1.5 | 6.0 | GO:0015556 | C4-dicarboxylate transmembrane transporter activity(GO:0015556) |
1.5 | 6.0 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
1.3 | 4.0 | GO:0004088 | carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
1.3 | 3.9 | GO:0048038 | quinone binding(GO:0048038) |
1.3 | 5.0 | GO:0016885 | ligase activity, forming carbon-carbon bonds(GO:0016885) |
1.2 | 15.0 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
1.2 | 5.0 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
1.2 | 4.7 | GO:0001091 | RNA polymerase II basal transcription factor binding(GO:0001091) TFIIH-class transcription factor binding(GO:0001097) |
1.1 | 3.3 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
1.1 | 14.1 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389) |
1.0 | 4.1 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
1.0 | 1.9 | GO:0004448 | isocitrate dehydrogenase activity(GO:0004448) |
0.9 | 2.8 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.9 | 2.6 | GO:0004108 | citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440) |
0.9 | 2.6 | GO:0003954 | NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.8 | 2.5 | GO:0016289 | CoA hydrolase activity(GO:0016289) |
0.8 | 6.4 | GO:0016679 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.8 | 5.4 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
0.8 | 7.6 | GO:0016675 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.8 | 3.8 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
0.7 | 1.3 | GO:0015489 | putrescine transmembrane transporter activity(GO:0015489) |
0.6 | 3.9 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.6 | 2.5 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
0.6 | 6.4 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
0.5 | 7.1 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
0.5 | 1.6 | GO:0047066 | phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066) |
0.5 | 2.0 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.5 | 2.0 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
0.5 | 1.5 | GO:0004619 | phosphoglycerate mutase activity(GO:0004619) |
0.5 | 2.0 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
0.5 | 3.5 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
0.5 | 7.7 | GO:0046906 | heme binding(GO:0020037) tetrapyrrole binding(GO:0046906) |
0.5 | 1.4 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.4 | 1.8 | GO:0016411 | acylglycerol O-acyltransferase activity(GO:0016411) |
0.4 | 4.8 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
0.4 | 0.9 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116) |
0.4 | 3.4 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.4 | 1.7 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
0.4 | 2.7 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.4 | 9.1 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.4 | 1.8 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
0.4 | 1.1 | GO:0015294 | solute:cation symporter activity(GO:0015294) |
0.3 | 1.7 | GO:0005354 | galactose transmembrane transporter activity(GO:0005354) |
0.3 | 0.9 | GO:0008902 | hydroxymethylpyrimidine kinase activity(GO:0008902) phosphomethylpyrimidine kinase activity(GO:0008972) |
0.3 | 1.5 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.3 | 2.9 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.3 | 1.7 | GO:0030246 | carbohydrate binding(GO:0030246) |
0.3 | 1.7 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.3 | 0.8 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
0.3 | 2.4 | GO:0016723 | ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) |
0.3 | 1.3 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
0.3 | 0.8 | GO:0015293 | symporter activity(GO:0015293) |
0.3 | 1.8 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) peroxiredoxin activity(GO:0051920) |
0.3 | 2.3 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
0.3 | 0.8 | GO:0004555 | alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927) |
0.2 | 2.0 | GO:0015205 | nucleobase transmembrane transporter activity(GO:0015205) |
0.2 | 6.5 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.2 | 1.6 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.2 | 3.0 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
0.2 | 1.3 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
0.2 | 0.9 | GO:0042927 | siderophore transmembrane transporter activity(GO:0015343) iron chelate transmembrane transporter activity(GO:0015603) siderophore transporter activity(GO:0042927) |
0.2 | 0.2 | GO:0005346 | purine ribonucleotide transmembrane transporter activity(GO:0005346) |
0.2 | 2.6 | GO:0015616 | DNA translocase activity(GO:0015616) |
0.2 | 5.6 | GO:0008234 | cysteine-type peptidase activity(GO:0008234) |
0.2 | 0.7 | GO:0005310 | dicarboxylic acid transmembrane transporter activity(GO:0005310) |
0.2 | 0.5 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
0.2 | 0.8 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
0.2 | 0.6 | GO:0016531 | copper chaperone activity(GO:0016531) |
0.2 | 0.6 | GO:0008169 | C-methyltransferase activity(GO:0008169) |
0.2 | 0.8 | GO:0018456 | aryl-alcohol dehydrogenase (NAD+) activity(GO:0018456) |
0.2 | 1.8 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.1 | 2.1 | GO:0016645 | oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645) |
0.1 | 0.4 | GO:0004672 | protein kinase activity(GO:0004672) |
0.1 | 0.6 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
0.1 | 1.3 | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) |
0.1 | 1.1 | GO:0035064 | methylated histone binding(GO:0035064) |
0.1 | 2.1 | GO:0015297 | antiporter activity(GO:0015297) |
0.1 | 1.9 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
0.1 | 0.1 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
0.1 | 1.1 | GO:0099600 | receptor activity(GO:0004872) transmembrane signaling receptor activity(GO:0004888) signaling receptor activity(GO:0038023) molecular transducer activity(GO:0060089) transmembrane receptor activity(GO:0099600) |
0.1 | 14.0 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
0.1 | 0.4 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.1 | 12.8 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
0.1 | 0.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
0.1 | 0.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.1 | 0.2 | GO:0001026 | transcription factor activity, core RNA polymerase III binding(GO:0000995) TFIIIB-type transcription factor activity(GO:0001026) |
0.1 | 0.5 | GO:0019104 | DNA N-glycosylase activity(GO:0019104) |
0.1 | 0.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
0.1 | 0.5 | GO:0008198 | ferrous iron binding(GO:0008198) |
0.1 | 0.3 | GO:0016653 | oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653) |
0.1 | 1.1 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
0.1 | 0.7 | GO:0051184 | cofactor transporter activity(GO:0051184) |
0.1 | 0.4 | GO:0015146 | pentose transmembrane transporter activity(GO:0015146) |
0.1 | 0.8 | GO:0005507 | copper ion binding(GO:0005507) |
0.1 | 0.2 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) peptidase inhibitor activity(GO:0030414) |
0.1 | 0.6 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.1 | 0.1 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) alcohol dehydrogenase (NADP+) activity(GO:0008106) |
0.1 | 0.1 | GO:0019903 | phosphatase binding(GO:0019902) protein phosphatase binding(GO:0019903) |
0.1 | 0.2 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
0.1 | 0.3 | GO:0016782 | transferase activity, transferring sulfur-containing groups(GO:0016782) |
0.1 | 0.2 | GO:0045118 | azole transporter activity(GO:0045118) |
0.1 | 0.2 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
0.1 | 0.2 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
0.1 | 0.9 | GO:0051020 | GTPase binding(GO:0051020) |
0.1 | 0.3 | GO:0042123 | glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124) |
0.0 | 2.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.1 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
0.0 | 0.5 | GO:0000384 | first spliceosomal transesterification activity(GO:0000384) |
0.0 | 1.2 | GO:0008237 | metallopeptidase activity(GO:0008237) |
0.0 | 0.5 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.0 | 0.1 | GO:0004559 | alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923) |
0.0 | 0.1 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
0.0 | 0.2 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.0 | 0.6 | GO:0003684 | damaged DNA binding(GO:0003684) |
0.0 | 0.1 | GO:0008374 | O-acyltransferase activity(GO:0008374) |
0.0 | 1.9 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.0 | 0.8 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
0.0 | 0.5 | GO:0005509 | calcium ion binding(GO:0005509) |
0.0 | 0.1 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
0.0 | 0.1 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
0.0 | 0.5 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
0.0 | 0.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.1 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
0.0 | 0.1 | GO:0050661 | NADP binding(GO:0050661) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.4 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.9 | 2.7 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.6 | 1.9 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
0.5 | 4.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
0.3 | 1.6 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
0.1 | 0.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
0.1 | 0.5 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
0.1 | 0.4 | PID P73PATHWAY | p73 transcription factor network |
0.1 | 96.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
0.1 | 0.2 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.0 | 0.0 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 5.8 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
0.6 | 1.9 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.5 | 1.9 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
0.5 | 5.0 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
0.3 | 0.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
0.2 | 0.7 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
0.1 | 3.3 | REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS | Genes involved in Metabolism of lipids and lipoproteins |
0.1 | 0.7 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
0.1 | 0.5 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
0.1 | 94.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
0.1 | 0.3 | REACTOME CHROMOSOME MAINTENANCE | Genes involved in Chromosome Maintenance |
0.0 | 0.3 | REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES | Genes involved in Transmembrane transport of small molecules |
0.0 | 0.3 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
0.0 | 0.1 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
0.0 | 0.2 | REACTOME TRANSCRIPTION | Genes involved in Transcription |