Results for MIG1
Z-value: 1.45
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Transcription factors associated with MIG1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
MIG1
|
S000003003 | Transcription factor involved in glucose repression |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YDR342C Show fit | 19.01 |
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels |
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| YJL133C-A Show fit | 17.91 |
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
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| YGR067C Show fit | 17.62 |
Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p |
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| YDL210W Show fit | 15.41 |
Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane |
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| YPR030W Show fit | 13.89 |
Nuclear protein with a potential regulatory role in utilization of galactose and nonfermentable carbon sources; overproduction suppresses the lethality at high temperature of a chs5 spa2 double null mutation; potential Cdc28p substrate |
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| YFL052W Show fit | 13.20 |
Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity |
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| YIL162W Show fit | 13.03 |
Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively |
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| YLR327C Show fit | 12.50 |
Protein of unknown function that associates with ribosomes |
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| YAR035W Show fit | 12.32 |
Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated |
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| YFR053C Show fit | 11.30 |
Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p |
Network of associatons between targets according to the STRING database.
First level regulatory network of MIG1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 21.2 | GO:0005978 | glycogen biosynthetic process(GO:0005978) |
| 4.2 | 16.7 | GO:0015847 | putrescine transport(GO:0015847) |
| 5.3 | 15.8 | GO:0009437 | amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437) |
| 3.7 | 14.9 | GO:0006848 | pyruvate transport(GO:0006848) |
| 2.1 | 14.6 | GO:0000023 | maltose metabolic process(GO:0000023) |
| 1.6 | 14.1 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
| 4.4 | 13.1 | GO:0015755 | fructose transport(GO:0015755) |
| 2.2 | 13.0 | GO:0005985 | sucrose metabolic process(GO:0005985) sucrose catabolic process(GO:0005987) |
| 2.1 | 12.8 | GO:0000128 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 4.1 | 12.2 | GO:0019413 | acetate biosynthetic process(GO:0019413) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 69.7 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.3 | 40.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.4 | 21.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 16.3 | GO:0000324 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
| 2.0 | 16.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.6 | 12.8 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.3 | 12.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 1.2 | 11.1 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.2 | 8.3 | GO:0005576 | extracellular region(GO:0005576) |
| 0.8 | 7.6 | GO:0070069 | cytochrome complex(GO:0070069) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.7 | 33.4 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 5.3 | 15.8 | GO:0016406 | carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406) |
| 1.2 | 15.0 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 4.7 | 14.2 | GO:0004575 | beta-fructofuranosidase activity(GO:0004564) sucrose alpha-glucosidase activity(GO:0004575) |
| 1.1 | 14.1 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389) |
| 0.1 | 14.0 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.1 | 12.8 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 3.1 | 12.5 | GO:0005537 | mannose binding(GO:0005537) |
| 2.0 | 12.2 | GO:0004030 | aldehyde dehydrogenase (NAD) activity(GO:0004029) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 3.3 | 9.9 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 96.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.5 | 4.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 1.1 | 3.4 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.9 | 2.7 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.6 | 1.9 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.3 | 1.6 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 0.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 0.5 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 0.4 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 0.2 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 94.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 1.9 | 5.8 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.5 | 5.0 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 0.1 | 3.3 | REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS | Genes involved in Metabolism of lipids and lipoproteins |
| 0.6 | 1.9 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.5 | 1.9 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.2 | 0.7 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 0.7 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.3 | 0.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 0.5 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |