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Results for GAL80

Z-value: 1.06

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Transcription factors associated with GAL80

Gene Symbol Gene ID Gene Info
GAL80
S000004515 Transcriptional regulator involved in the repression of GAL genes

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GAL80YML051W-0.653.6e-04Click!

Activity profile of GAL80 motif

Sorted Z-values of GAL80 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YNL178W 13.57
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YLR154W-B 6.60 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154W-A 6.57 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154C 6.06
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YOL086C 5.64
ADH1
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
YHR010W 4.98
RPL27A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein
YDL023C 4.73 Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance
YDR508C 4.31
GNP1
High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids
YDR509W 4.30 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YJR105W 4.28
ADO1
Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle
YDR098C 4.14
GRX3
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
YDL022W 3.97
GPD1
NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p
YER102W 3.93
RPS8B
Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and has similarity to rat S8 ribosomal protein
YDL085C-A 3.91 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YIL009W 3.90
FAA3
Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YJL158C 3.49
CIS3
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
YDL022C-A 3.46 Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene DIA3; identified by fungal homology and RT-PCR
YIL009C-A 3.32
EST3
Component of the telomerase holoenzyme, involved in telomere replication
YPL112C 3.18
PEX25
Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with homologous protein Pex27p
YGR138C 3.13
TPO2
Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily
YLR154W-C 3.08
TAR1
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand
YKR038C 3.05
KAE1
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex
YLR109W 3.01
AHP1
Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p
YLR110C 2.97
CCW12
Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor
YDR344C 2.96 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDR345C 2.84
HXT3
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
YFL022C 2.76
FRS2
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
YDR279W 2.74
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YMR009W 2.74
ADI1
Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; transcribed with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions
YEL056W 2.71
HAT2
Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing
YML026C 2.68
RPS18B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins
YDR417C 2.62 Hypothetical protein
YBR032W 2.61 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data
YNL030W 2.60
HHF2
One of two identical histone H4 proteins (see also HHF1); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity
YLR441C 2.56
RPS1A
Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Bp and has similarity to rat S3a ribosomal protein
YML063W 2.54
RPS1B
Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein
YOL085C 2.50 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOL085W-A
YKL182W 2.43
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YMR199W 2.41
CLN1
G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
YOL039W 2.40
RPP2A
Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
YGR148C 2.37
RPL24B
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YNL327W 2.36
EGT2
Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner
YMR049C 2.32
ERB1
Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
YKR092C 2.30
SRP40
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YEL001C 2.30
IRC22
Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci
YJR094W-A 2.26
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YGR155W 2.26
CYS4
Cystathionine beta-synthase, catalyzes the synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis
YER001W 2.25
MNN1
Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family
YBL092W 2.24
RPL32
Protein component of the large (60S) ribosomal subunit, has similarity to rat L32 ribosomal protein; overexpression disrupts telomeric silencing
YIL052C 2.20
RPL34B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Ap and has similarity to rat L34 ribosomal protein
YGR279C 2.17
SCW4
Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating
YMR194W 2.14
RPL36A
N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Bp and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA
YLR081W 2.09
GAL2
Galactose permease, required for utilization of galactose; also able to transport glucose
YER074W 2.09
RPS24A
Protein component of the small (40S) ribosomal subunit; identical to Rps24Bp and has similarity to rat S24 ribosomal protein
YER023C-A 2.08 Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps verified gene PRO3; identified by gene-trapping, microarray expression analysis, and genome-wide homology searching
YMR083W 2.04
ADH3
Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production
YLR355C 2.04
ILV5
Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA and found in mitochondrial nucleoids
YOL040C 2.02
RPS15
Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S19 and rat S15 ribosomal proteins
YMR032W 2.00
HOF1
Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p
YNR001W-A 1.98 Dubious open reading frame unlikely to encode a functional protein; identified by homology
YGL039W 1.94 Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)
YER137C 1.93 Putative protein of unknown function
YGR140W 1.91
CBF2
Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo
YEL020C-B 1.87 Dubious open reading frame unlikely to encode a protein; partially overlaps verified gene YEL020W-A; identified by fungal homology and RT-PCR
YNL289W 1.87
PCL1
Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic cell cycle and regulation of morphogenesis, localizes to sites of polarized cell growth
YPR063C 1.83 ER-localized protein of unknown function
YEL054C 1.79
RPL12A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Bp; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins
YLR108C 1.78 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YLR108C is not an esssential gene
YFR055W 1.75
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YCL058C 1.75
FYV5
Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in ion homeostasis
YPL014W 1.72 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus
YJR145C 1.65
RPS4A
Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein
YGR139W 1.65 Dubious ORF unlikely to encode a functional protein, based on available experimental and comparative sequence data
YER177W 1.63
BMH1
14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling
YDL241W 1.60 Putative protein of unknown function; YDL241W is not an essential gene
YDL047W 1.60
SIT4
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
YDR400W 1.59
URH1
Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways
YIL123W 1.58
SIM1
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated
YLR183C 1.57
TOS4
Transcription factor that binds to a number of promoter regions, particularly promoters of some genes involved in pheromone response and cell cycle; potential Cdc28p substrate; expression is induced in G1 by bound SBF
YHR021C 1.56
RPS27B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Ap and has similarity to rat S27 ribosomal protein
YER056C-A 1.55
RPL34A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Bp and has similarity to rat L34 ribosomal protein
YGL040C 1.53
HEM2
Delta-aminolevulinate dehydratase, a homo-octameric enzyme, catalyzes the conversion of delta-aminolevulinic acid to porphobilinogen, the second step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus
YCL064C 1.49
CHA1
Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine
YLR351C 1.49
NIT3
Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member
YCL063W 1.49
VAC17
Protein involved in vacuole inheritance; acts as a vacuole-specific receptor for myosin Myo2p
YIL158W 1.48
AIM20
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; null mutant displays increased frequency of mitochondrial genome loss (petite formation)
YLR344W 1.48
RPL26A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Bp and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA
YMR144W 1.47 Putative protein of unknown function; localized to the nucleus; YMR144W is not an essential gene
YBR112C 1.47
CYC8
General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters
YIL056W 1.43
VHR1
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations
YGL034C 1.43 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDL075W 1.42
RPL31A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YFR056C 1.41 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YDR156W 1.41
RPA14
RNA polymerase I subunit A14
YNL031C 1.39
HHT2
One of two identical histone H3 proteins (see also HHT1); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation
YHR094C 1.38
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YKL120W 1.36
OAC1
Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and thiosulfate; member of the mitochondrial carrier family
YLR185W 1.35
RPL37A
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Bp and to rat L37 ribosomal protein
YML103C 1.32
NUP188
Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex and of the nuclear envelope, also involved in nuclear envelope permeability, interacts with Pom152p and Nic96p
YJL196C 1.31
ELO1
Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids
YMR105W-A 1.31 Putative protein of unknown function
YGR251W 1.30 Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene
YOR092W 1.29
ECM3
Non-essential protein of unknown function; involved in signal transduction and the genotoxic response; induced rapidly in response to treatment with 8-methoxypsoralen and UVA irradiation
YHR216W 1.28
IMD2
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation
YOR130C 1.27
ORT1
Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome
YLR257W 1.26 Putative protein of unknown function
YEL038W 1.26
UTR4
Protein of unknown function with sequence similarity to 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatases, found in both the cytoplasm and nucleus
YBR113W 1.25 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene CYC8
YPL265W 1.24
DIP5
Dicarboxylic amino acid permease, mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate; also a transporter for Gln, Asn, Ser, Ala, and Gly
YML123C 1.24
PHO84
High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p
YER088C-A 1.24 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGL009C 1.23
LEU1
Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway
YNL058C 1.21 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL058C is not an essential gene
YJL216C 1.21 Protein of unknown function, similar to alpha-D-glucosidases; transcriptionally activated by both Pdr8p and Yrm1p, along with transporters and other genes involved in the pleiotropic drug resistance (PDR) phenomenon
YDR033W 1.20
MRH1
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p
YDR112W 1.20
IRC2
Dubious open reading frame, unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR111C; null mutant displays increased levels of spontaneous Rad52p foci
YHR043C 1.20
DOG2
2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, similar to Dog1p, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed
YLR042C 1.19 Protein of unknown function; localizes to the cytoplasm; YLL042C is not an essential gene
YOR096W 1.16
RPS7A
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins
YER028C 1.15
MIG3
Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes
YIL148W 1.14
RPL40A
Fusion protein, identical to Rpl40Bp, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes
YCL018W 1.14
LEU2
Beta-isopropylmalate dehydrogenase (IMDH), catalyzes the third step in the leucine biosynthesis pathway
YNL057W 1.11 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YFR031C-A 1.11
RPL2A
Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins
YLR437C 1.10 Putative protein of unknown function; epitope tagged protein localizes to the cytoplasm
YGR090W 1.08
UTP22
Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
YAL038W 1.07
CDC19
Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration
YDL137W 1.05
ARF2
ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf1p
YGR040W 1.02
KSS1
Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains
YIL053W 1.01
RHR2
Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress
YMR246W 1.01
FAA4
Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids
YGL106W 1.00
MLC1
Essential light chain for Myo1p, light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition
YDR111C 0.98
ALT2
Putative alanine transaminase (glutamic pyruvic transaminase)
YDR395W 0.97
SXM1
Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm; similar to Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1
YGR055W 0.97
MUP1
High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake
YDL211C 0.96 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
YML111W 0.95
BUL2
Component of the Rsp5p E3-ubiquitin ligase complex, involved in intracellular amino acid permease sorting, functions in heat shock element mediated gene expression, essential for growth in stress conditions, functional homolog of BUL1
YLL045C 0.95
RPL8B
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
YJL200C 0.92
ACO2
Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol
YKL218C 0.91
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YCR102W-A 0.90 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YOR119C 0.89
RIO1
Essential serine kinase involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA
YGL201C 0.89
MCM6
Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
YKL110C 0.89
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YML064C 0.88
TEM1
GTP-binding protein of the ras superfamily involved in termination of M-phase; controls actomyosin and septin dynamics during cytokinesis
YHL003C 0.88
LAG1
Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p
YHR140W 0.88 Putative integral membrane protein of unknown function
YLR328W 0.87
NMA1
Nicotinic acid mononucleotide adenylyltransferase, involved in pathways of NAD biosynthesis, including the de novo, NAD(+) salvage, and nicotinamide riboside salvage pathways
YOR342C 0.87 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus
YPL250W-A 0.87 Identified by fungal homology and RT-PCR
YDR037W 0.87
KRS1
Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis
YAR029W 0.87 Member of DUP240 gene family but contains no transmembrane domains; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YKR093W 0.87
PTR2
Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p
YPR074C 0.86
TKL1
Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
YLR411W 0.85
CTR3
High-affinity copper transporter of the plasma membrane, acts as a trimer; gene is disrupted by a Ty2 transposon insertion in many laboratory strains of S. cerevisiae
YKL030W 0.85 Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; partially overlaps the verified gene MAE1
YFL026W 0.85
STE2
Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells
YPR014C 0.84 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPR014C is not an essential gene
YPR170W-B 0.83 Putative protein of unknown function, conserved in fungi; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C
YBR118W 0.82
TEF2
Translational elongation factor EF-1 alpha; also encoded by TEF1; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes
YBR106W 0.81
PHO88
Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations
YGL031C 0.81
RPL24A
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YLL027W 0.81
ISA1
Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources
YML102W 0.80
CAC2
Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans
YCR102C 0.78 Putative protein of unknown function; involved in copper metabolism; similar to C.carbonum toxD gene; YCR102C is not an essential gene
YMR008C 0.78
PLB1
Phospholipase B (lysophospholipase) involved in lipid metabolism, required for deacylation of phosphatidylcholine and phosphatidylethanolamine but not phosphatidylinositol
YNR016C 0.78
ACC1
Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids
YJR114W 0.77 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RSM7/YJR113C
YGL030W 0.77
RPL30
Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript
YMR290C 0.76
HAS1
ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles
YLR043C 0.76
TRX1
Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance
YJL198W 0.75
PHO90
Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YOL155C 0.75
HPF1
Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines
YDR041W 0.74
RSM10
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins
YOR029W 0.74 Dubious open reading frame unlikely to encode a functional protein; based on available experimental and comparative sequence data
YHR208W 0.74
BAT1
Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase
YDR510W 0.73
SMT3
Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics
YPL211W 0.73
NIP7
Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p
YJR123W 0.72
RPS5
Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins
YMR290W-A 0.71 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase
YKR075C 0.71 Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YJR104C 0.71
SOD1
Cytosolic superoxide dismutase; some mutations are analogous to those that cause ALS (amyotrophic lateral sclerosis) in humans
YIL163C 0.71 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YHR162W 0.70 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion
YCL050C 0.69
APA1
Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa2p
YDR040C 0.69
ENA1
P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
YIR031C 0.69
DAL7
Malate synthase, role in allantoin degradation unknown; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
YDR047W 0.69
HEM12
Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; activity inhibited by Cu2+, Zn2+, Fe2+, Fe3+ and sulfhydryl-specific reagents
YIL164C 0.68
NIT1
Nitrilase, member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene
YDL205C 0.67
HEM3
Phorphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p
YGL148W 0.67
ARO2
Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids
YNL239W 0.66
LAP3
Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH
YPL143W 0.66
RPL33A
N-terminally acetylated ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Bp and has similarity to rat L35a; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable
YGL105W 0.66
ARC1
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm; also binds quadruplex nucleic acids
YDR008C 0.66 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YDR155C 0.64
CPR1
Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A
YOR028C 0.64
CIN5
Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus
YJR113C 0.64
RSM7
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S7 ribosomal protein
YNL069C 0.63
RPL16B
N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Ap, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p
YBR084C-A 0.62
RPL19A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Bp and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal

Network of associatons between targets according to the STRING database.

First level regulatory network of GAL80

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0044209 AMP salvage(GO:0044209)
1.3 14.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
1.3 8.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
1.2 5.9 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
1.0 4.0 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.9 2.8 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.8 3.4 GO:0000296 spermine transport(GO:0000296)
0.8 7.4 GO:0000947 amino acid catabolic process to alcohol via Ehrlich pathway(GO:0000947)
0.8 2.4 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.7 3.0 GO:0098742 agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.7 2.1 GO:2000877 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
0.6 2.3 GO:0019346 transsulfuration(GO:0019346)
0.5 1.6 GO:1904667 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.5 1.6 GO:0042454 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) ribonucleoside catabolic process(GO:0042454) cytidine metabolic process(GO:0046087)
0.5 4.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.5 2.0 GO:0009099 valine biosynthetic process(GO:0009099)
0.5 1.5 GO:0006567 threonine catabolic process(GO:0006567)
0.5 2.3 GO:0009098 leucine biosynthetic process(GO:0009098)
0.5 1.4 GO:0008272 sulfate transport(GO:0008272) C4-dicarboxylate transport(GO:0015740)
0.4 1.3 GO:0046039 GTP biosynthetic process(GO:0006183) GTP metabolic process(GO:0046039)
0.4 2.9 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.4 2.3 GO:0006491 N-glycan processing(GO:0006491)
0.4 1.9 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.4 57.5 GO:0002181 cytoplasmic translation(GO:0002181)
0.3 2.7 GO:0016559 peroxisome fission(GO:0016559)
0.3 2.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.3 1.0 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.3 1.7 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.3 1.3 GO:0030497 fatty acid elongation(GO:0030497)
0.3 2.2 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.3 1.2 GO:0071478 response to UV(GO:0009411) cellular response to radiation(GO:0071478) cellular response to light stimulus(GO:0071482)
0.3 2.4 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.3 4.7 GO:0032508 DNA duplex unwinding(GO:0032508)
0.2 2.6 GO:0090529 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529)
0.2 0.7 GO:0009164 nucleoside catabolic process(GO:0009164) glycosyl compound catabolic process(GO:1901658)
0.2 0.7 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.2 0.9 GO:1900434 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
0.2 0.9 GO:0042938 dipeptide transport(GO:0042938)
0.2 0.9 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin structure organization(GO:0031032) actomyosin contractile ring organization(GO:0044837)
0.2 1.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 1.9 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.2 1.7 GO:0006797 polyphosphate metabolic process(GO:0006797)
0.2 0.6 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 5.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 1.4 GO:0006814 sodium ion transport(GO:0006814)
0.2 0.5 GO:0001196 regulation of mating-type specific transcription from RNA polymerase II promoter(GO:0001196) negative regulation of mating-type specific transcription from RNA polymerase II promoter(GO:0001198) negative regulation of cellular amine metabolic process(GO:0033239) regulation of cellular amine catabolic process(GO:0033241) negative regulation of mating-type specific transcription, DNA-templated(GO:0045894) positive regulation of mating-type specific transcription, DNA-templated(GO:0045895)
0.2 0.5 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.2 0.5 GO:0000101 sulfur amino acid transport(GO:0000101)
0.2 0.8 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.2 0.7 GO:0009423 chorismate biosynthetic process(GO:0009423)
0.2 0.5 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.2 0.6 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.2 0.6 GO:0019287 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.2 1.1 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.1 0.6 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.9 GO:0000084 mitotic S phase(GO:0000084) S phase(GO:0051320)
0.1 0.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 0.6 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.8 GO:0009102 biotin metabolic process(GO:0006768) biotin biosynthetic process(GO:0009102)
0.1 0.8 GO:0048255 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.1 0.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636) unsaturated fatty acid metabolic process(GO:0033559)
0.1 0.5 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.1 0.6 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.1 1.0 GO:0001402 signal transduction involved in filamentous growth(GO:0001402)
0.1 0.9 GO:0006672 ceramide metabolic process(GO:0006672) ceramide biosynthetic process(GO:0046513)
0.1 1.0 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.8 GO:0030031 cell projection organization(GO:0030030) cell projection assembly(GO:0030031)
0.1 1.3 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 0.4 GO:0000092 mitotic anaphase B(GO:0000092) plasmid partitioning(GO:0030541)
0.1 1.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 1.0 GO:0031070 intronic snoRNA processing(GO:0031070) intronic box C/D snoRNA processing(GO:0034965)
0.1 2.8 GO:0008361 regulation of cell size(GO:0008361)
0.1 0.2 GO:0009090 homoserine biosynthetic process(GO:0009090)
0.1 0.3 GO:0009097 isoleucine biosynthetic process(GO:0009097)
0.1 0.5 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 0.6 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.1 1.5 GO:0000011 vacuole inheritance(GO:0000011)
0.1 0.3 GO:0048313 Golgi inheritance(GO:0048313)
0.1 0.8 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 1.2 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.4 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 1.9 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.1 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.2 GO:0038032 termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.6 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 1.0 GO:0007120 axial cellular bud site selection(GO:0007120)
0.1 0.7 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.7 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.6 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.1 0.3 GO:0050810 regulation of steroid metabolic process(GO:0019218) regulation of ergosterol biosynthetic process(GO:0032443) regulation of steroid biosynthetic process(GO:0050810)
0.1 3.6 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.1 1.6 GO:0032005 pheromone-dependent signal transduction involved in conjugation with cellular fusion(GO:0000750) signal transduction involved in conjugation with cellular fusion(GO:0032005)
0.1 0.3 GO:0030042 actin filament depolymerization(GO:0030042)
0.1 0.2 GO:0048209 regulation of COPII vesicle coating(GO:0003400) regulation of vesicle targeting, to, from or within Golgi(GO:0048209) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.1 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.3 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 0.5 GO:0052803 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.1 0.3 GO:0090158 regulation of phosphatidylinositol dephosphorylation(GO:0060304) endoplasmic reticulum membrane organization(GO:0090158)
0.1 1.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0051457 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674) maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0032365 intracellular lipid transport(GO:0032365)
0.0 2.8 GO:0000747 conjugation with cellular fusion(GO:0000747)
0.0 0.2 GO:0051597 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
0.0 3.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.2 GO:0042435 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.0 1.8 GO:0000910 cytokinesis(GO:0000910)
0.0 1.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 1.0 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 3.6 GO:0006913 nucleocytoplasmic transport(GO:0006913)
0.0 0.3 GO:0031120 tRNA pseudouridine synthesis(GO:0031119) snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031)
0.0 0.1 GO:0044206 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.0 0.6 GO:0051666 actin cortical patch localization(GO:0051666)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0010458 exit from mitosis(GO:0010458)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0007009 plasma membrane organization(GO:0007009)
0.0 1.1 GO:0006694 steroid biosynthetic process(GO:0006694) sterol biosynthetic process(GO:0016126)
0.0 0.1 GO:0044070 regulation of anion transport(GO:0044070)
0.0 0.3 GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled(GO:0030846)
0.0 0.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.7 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.0 0.1 GO:0015883 FAD transport(GO:0015883)
0.0 0.2 GO:0061572 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.0 0.3 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.9 GO:0046939 nucleotide phosphorylation(GO:0046939)
0.0 0.2 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.2 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.4 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0 0.6 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:0070096 mitochondrial outer membrane translocase complex assembly(GO:0070096)
0.0 0.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.0 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.0 0.1 GO:0010688 negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter(GO:0010688)
0.0 0.2 GO:0051668 localization within membrane(GO:0051668)
0.0 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 2.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0034401 chromatin organization involved in regulation of transcription(GO:0034401)
0.0 0.2 GO:0030474 spindle pole body duplication(GO:0030474)
0.0 0.2 GO:0044396 actin cortical patch assembly(GO:0000147) actin cortical patch organization(GO:0044396)
0.0 0.5 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.1 GO:0055075 cellular potassium ion homeostasis(GO:0030007) potassium ion homeostasis(GO:0055075)
0.0 0.1 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.7 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.5 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.0 GO:0015677 copper ion import(GO:0015677)
0.0 0.0 GO:0019419 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.0 0.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0006826 iron ion transport(GO:0006826)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.8 GO:0032299 ribonuclease H2 complex(GO:0032299)
1.3 4.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
1.1 13.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.8 2.4 GO:0030428 cell septum(GO:0030428)
0.8 2.3 GO:0070545 PeBoW complex(GO:0070545)
0.6 3.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.5 2.0 GO:0044697 HICS complex(GO:0044697)
0.5 1.9 GO:0031518 CBF3 complex(GO:0031518)
0.5 3.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.5 1.8 GO:0044611 nuclear pore inner ring(GO:0044611)
0.4 35.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 1.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.4 23.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 4.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 1.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 0.5 GO:0000786 nucleosome(GO:0000786)
0.2 3.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 0.7 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.2 1.0 GO:0032545 CURI complex(GO:0032545)
0.2 0.6 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 0.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.2 1.0 GO:0042555 MCM complex(GO:0042555)
0.2 0.6 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.6 GO:0034448 EGO complex(GO:0034448)
0.1 1.0 GO:0016459 myosin complex(GO:0016459)
0.1 0.4 GO:0008275 gamma-tubulin small complex, spindle pole body(GO:0000928) gamma-tubulin complex(GO:0000930) gamma-tubulin small complex(GO:0008275)
0.1 1.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.0 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) multimeric ribonuclease P complex(GO:0030681)
0.1 3.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 0.3 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.7 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 1.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 2.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.3 GO:0043529 GET complex(GO:0043529)
0.1 0.5 GO:0030478 actin cap(GO:0030478)
0.1 0.6 GO:0034967 Set3 complex(GO:0034967)
0.1 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 6.0 GO:0005576 extracellular region(GO:0005576)
0.1 0.2 GO:0031985 Golgi cisterna(GO:0031985)
0.1 0.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.7 GO:0005940 septin ring(GO:0005940)
0.1 0.4 GO:0005871 kinesin complex(GO:0005871)
0.1 3.3 GO:0044445 cytosolic part(GO:0044445)
0.1 0.6 GO:0000243 commitment complex(GO:0000243)
0.1 0.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.4 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.3 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.4 GO:0030867 rough endoplasmic reticulum(GO:0005791) rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.6 GO:0016586 RSC complex(GO:0016586)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 1.5 GO:0030686 90S preribosome(GO:0030686)
0.0 4.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.3 GO:0034399 nuclear periphery(GO:0034399)
0.0 3.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.0 GO:0000131 incipient cellular bud site(GO:0000131)
0.0 0.3 GO:0036452 ESCRT complex(GO:0036452)
0.0 0.3 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 2.9 GO:0005730 nucleolus(GO:0005730)
0.0 1.6 GO:0005933 cellular bud(GO:0005933)
0.0 0.3 GO:0099512 supramolecular fiber(GO:0099512) polymeric cytoskeletal fiber(GO:0099513)
0.0 0.8 GO:0005815 microtubule organizing center(GO:0005815) spindle pole body(GO:0005816)
0.0 0.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0070210 Rpd3L-Expanded complex(GO:0070210)
0.0 0.2 GO:0005802 trans-Golgi network(GO:0005802)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 13.6 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
2.2 8.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.3 3.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.2 7.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
1.1 4.4 GO:0019206 nucleoside kinase activity(GO:0019206)
0.9 2.8 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.8 3.4 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.6 2.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.6 2.4 GO:0016417 S-acyltransferase activity(GO:0016417)
0.6 2.4 GO:0016841 ammonia-lyase activity(GO:0016841)
0.6 1.2 GO:0015645 long-chain fatty acid-CoA ligase activity(GO:0004467) fatty acid ligase activity(GO:0015645)
0.6 3.5 GO:0005354 galactose transmembrane transporter activity(GO:0005354)
0.5 1.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.5 2.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.5 1.4 GO:0019003 GDP binding(GO:0019003)
0.5 1.4 GO:0015116 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.4 1.3 GO:0009922 fatty acid elongase activity(GO:0009922)
0.4 1.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.4 1.6 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.4 2.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.4 1.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.3 0.7 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.3 1.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.3 3.8 GO:0005199 structural constituent of cell wall(GO:0005199)
0.3 2.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.3 60.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 0.8 GO:0015088 copper uptake transmembrane transporter activity(GO:0015088)
0.3 0.8 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.3 1.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.3 6.0 GO:0016836 hydro-lyase activity(GO:0016836)
0.3 4.3 GO:0042803 protein homodimerization activity(GO:0042803)
0.2 3.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 1.5 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.2 1.9 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 0.9 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 0.9 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 1.0 GO:0017022 myosin binding(GO:0017022)
0.2 0.8 GO:0016885 ligase activity, forming carbon-carbon bonds(GO:0016885)
0.2 5.3 GO:0046982 protein heterodimerization activity(GO:0046982)
0.2 0.5 GO:0016504 peptidase activator activity(GO:0016504)
0.2 0.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 1.8 GO:0043495 protein anchor(GO:0043495)
0.2 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.2 3.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 0.6 GO:0004338 glucan exo-1,3-beta-glucosidase activity(GO:0004338)
0.1 1.8 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.1 0.4 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.1 1.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.5 GO:0016725 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.4 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.0 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 4.1 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) hydrolase activity, acting on glycosyl bonds(GO:0016798)
0.1 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.6 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.1 2.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.3 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1 1.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.7 GO:0031386 protein tag(GO:0031386)
0.1 0.3 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 1.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.4 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.1 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.1 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.6 GO:0008144 drug binding(GO:0008144)
0.1 3.0 GO:0042393 histone binding(GO:0042393)
0.1 1.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.1 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.1 0.7 GO:0015079 potassium ion transmembrane transporter activity(GO:0015079)
0.1 0.2 GO:0019202 amino acid kinase activity(GO:0019202)
0.1 0.2 GO:0008251 adenosine deaminase activity(GO:0004000) tRNA-specific adenosine deaminase activity(GO:0008251)
0.1 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.7 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.1 0.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.2 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.1 0.3 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.8 GO:0051287 NAD binding(GO:0051287)
0.0 2.1 GO:0008092 cytoskeletal protein binding(GO:0008092)
0.0 0.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.6 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 1.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)
0.0 0.1 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0072509 divalent inorganic cation transmembrane transporter activity(GO:0072509)
0.0 0.2 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 PID SHP2 PATHWAY SHP2 signaling
0.3 0.3 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.1 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 16.3 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
1.0 4.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.9 2.8 REACTOME INSULIN RECEPTOR SIGNALLING CASCADE Genes involved in Insulin receptor signalling cascade
0.9 2.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.7 12.0 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.4 1.3 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.3 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 0.7 REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION Genes involved in Platelet activation, signaling and aggregation
0.1 1.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.0 0.2 REACTOME SIGNALING BY GPCR Genes involved in Signaling by GPCR
0.0 0.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis