Results for GAL80
Z-value: 1.06
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Transcription factors associated with GAL80
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
GAL80
|
S000004515 | Transcriptional regulator involved in the repression of GAL genes |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YNL178W Show fit | 13.57 |
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins |
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| YLR154W-B Show fit | 6.60 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YLR154W-A Show fit | 6.57 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YLR154C Show fit | 6.06 |
Ribonuclease H2 subunit, required for RNase H2 activity |
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| YOL086C Show fit | 5.64 |
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway |
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| YHR010W Show fit | 4.98 |
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein |
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| YDL023C Show fit | 4.73 |
Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance |
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| YDR508C Show fit | 4.31 |
High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids |
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| YDR509W Show fit | 4.30 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
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| YJR105W Show fit | 4.28 |
Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle |
Network of associatons between targets according to the STRING database.
First level regulatory network of GAL80
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 57.5 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 1.3 | 14.2 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 1.3 | 8.8 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.8 | 7.4 | GO:0000947 | amino acid catabolic process to alcohol via Ehrlich pathway(GO:0000947) |
| 1.2 | 5.9 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
| 0.2 | 5.4 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.5 | 4.7 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 0.3 | 4.7 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
| 1.4 | 4.3 | GO:0044209 | AMP salvage(GO:0044209) |
| 1.0 | 4.0 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 35.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.4 | 23.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 1.1 | 13.6 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 2.9 | 8.8 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.1 | 6.0 | GO:0005576 | extracellular region(GO:0005576) |
| 0.4 | 4.7 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 1.3 | 4.0 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 4.0 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 3.4 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.5 | 3.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 60.0 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 2.3 | 13.6 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 2.2 | 8.8 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 1.2 | 7.4 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.3 | 6.0 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.2 | 5.3 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 1.1 | 4.4 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
| 0.3 | 4.3 | GO:0042803 | protein homodimerization activity(GO:0042803) |
| 0.1 | 4.1 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) hydrolase activity, acting on glycosyl bonds(GO:0016798) |
| 1.3 | 3.9 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.8 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 0.7 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 0.4 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.3 | 0.3 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 0.1 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.1 | PID NOTCH PATHWAY | Notch signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 16.3 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.7 | 12.0 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 1.0 | 4.0 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.9 | 2.8 | REACTOME INSULIN RECEPTOR SIGNALLING CASCADE | Genes involved in Insulin receptor signalling cascade |
| 0.9 | 2.7 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.4 | 1.3 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.1 | 1.0 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.3 | 0.9 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.2 | 0.7 | REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | Genes involved in Platelet activation, signaling and aggregation |
| 0.2 | 0.4 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |