Results for FZF1
Z-value: 0.63
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Transcription factors associated with FZF1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
FZF1
|
S000003223 | Transcription factor involved in sulfite metabolism |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YER137C Show fit | 1.73 |
Putative protein of unknown function |
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| YLR154W-A Show fit | 1.61 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YDR098C Show fit | 1.60 |
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage |
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| YLR154W-B Show fit | 1.54 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YLR154C Show fit | 1.37 |
Ribonuclease H2 subunit, required for RNase H2 activity |
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| YMR049C Show fit | 1.27 |
Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1 |
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| YGR040W Show fit | 1.27 |
Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains |
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| YER097W Show fit | 1.26 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
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| YLR154W-C Show fit | 1.18 |
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand |
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| YAL033W Show fit | 1.14 |
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends |
Network of associatons between targets according to the STRING database.
First level regulatory network of FZF1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.0 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.3 | 2.2 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.0 | 2.1 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.0 | 2.1 | GO:0006913 | nucleocytoplasmic transport(GO:0006913) |
| 0.2 | 1.4 | GO:0042538 | hyperosmotic salinity response(GO:0042538) |
| 0.2 | 1.3 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.1 | 1.3 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.0 | 1.3 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.2 | 1.2 | GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433) |
| 0.3 | 1.1 | GO:0036170 | filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 3.1 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 3.1 | GO:0005730 | nucleolus(GO:0005730) |
| 0.7 | 2.0 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.0 | 1.4 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.0 | 1.4 | GO:0000131 | incipient cellular bud site(GO:0000131) |
| 0.4 | 1.3 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.1 | 1.2 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 1.1 | GO:0030681 | nucleolar ribonuclease P complex(GO:0005655) multimeric ribonuclease P complex(GO:0030681) |
| 0.2 | 0.9 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.5 | 2.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 1.6 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.1 | 1.6 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 1.4 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.1 | 1.3 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 1.3 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.2 | 1.2 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.1 | 1.2 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.1 | 1.2 | GO:0042162 | telomeric DNA binding(GO:0042162) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 0.3 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 0.2 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.2 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.1 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 0.1 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.1 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.0 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.0 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.0 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.9 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.9 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.1 | 0.7 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.1 | 0.7 | REACTOME GPCR DOWNSTREAM SIGNALING | Genes involved in GPCR downstream signaling |
| 0.1 | 0.4 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 0.3 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.1 | 0.3 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.2 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.2 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 0.1 | REACTOME G1 PHASE | Genes involved in G1 Phase |