Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Zkscan1

Z-value: 0.65

Motif logo

logo of

Transcription factors associated with Zkscan1

Gene Symbol Gene ID Gene Info
Zkscan1
ENSRNOG00000001335 zinc finger with KRAB and SCAN domains 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zkscan1rn6_v1_chr12_+_19231092_192310920.435.3e-16Click!

Activity profile of Zkscan1 motif

Sorted Z-values of Zkscan1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_143059764 20.88 ENSRNOT00000010660
ENSRNOT00000087370
Krt7
keratin 7
chr14_+_1462358 20.60 ENSRNOT00000077243
Csf2ra
colony stimulating factor 2 receptor alpha subunit
chr8_+_55603968 18.77 ENSRNOT00000066848
Pou2af1
POU class 2 associating factor 1
chr10_-_65692016 17.72 ENSRNOT00000085074
ENSRNOT00000038690
Slc13a2
solute carrier family 13 member 2
chr7_-_119797098 16.36 ENSRNOT00000009994
Rac2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_+_89220083 15.77 ENSRNOT00000093144
Dmkn
dermokine
chr5_-_137112927 12.92 ENSRNOT00000078302
Ptprf
protein tyrosine phosphatase, receptor type, F
chr5_+_151413382 12.77 ENSRNOT00000012626
Cd164l2
CD164 molecule like 2
chr15_+_31642169 12.23 ENSRNOT00000072362
AABR07017833.1

chr2_-_219097619 12.16 ENSRNOT00000078806
Vcam1
vascular cell adhesion molecule 1
chr5_+_154522119 12.07 ENSRNOT00000072618
E2f2
E2F transcription factor 2
chr7_-_123767797 11.94 ENSRNOT00000012699
Tcf20
transcription factor 20
chr10_-_65424802 11.65 ENSRNOT00000018468
Traf4
Tnf receptor associated factor 4
chr12_+_943006 11.39 ENSRNOT00000001449
Kl
Klotho
chr3_-_1584946 11.35 ENSRNOT00000031058
Pax8
paired box 8
chr6_-_142585188 10.97 ENSRNOT00000067437
AABR07065815.1

chr6_-_138632159 10.88 ENSRNOT00000082921
ENSRNOT00000040702
Ighm
immunoglobulin heavy constant mu
chr13_+_90244681 10.37 ENSRNOT00000078162
Cd84
CD84 molecule
chr6_-_142635763 10.31 ENSRNOT00000048908
AABR07065815.2

chr12_-_36587839 10.16 ENSRNOT00000001295
Bri3bp
Bri3 binding protein
chr15_-_29446332 9.88 ENSRNOT00000082901
AABR07017634.1

chr7_-_126913585 9.53 ENSRNOT00000036025
Celsr1
cadherin, EGF LAG seven-pass G-type receptor 1
chr3_-_151625644 8.72 ENSRNOT00000026657
Rbm12
RNA binding motif protein 12
chr6_+_139486775 8.68 ENSRNOT00000077771
AABR07065699.3

chr18_-_69944632 8.64 ENSRNOT00000047271
Mapk4
mitogen-activated protein kinase 4
chr8_+_67295727 8.59 ENSRNOT00000020443
Anp32a
acidic nuclear phosphoprotein 32 family member A
chr16_-_39476384 8.47 ENSRNOT00000092968
Gpm6a
glycoprotein m6a
chr7_-_116504853 8.38 ENSRNOT00000056557
RGD1565410
similar to Ly6-C antigen gene
chr5_-_159602251 8.31 ENSRNOT00000011394
Necap2
NECAP endocytosis associated 2
chr1_-_262014066 8.11 ENSRNOT00000087083
Hps1
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chr19_-_55257876 7.85 ENSRNOT00000017564
Cyba
cytochrome b-245 alpha chain
chr16_-_39476025 7.34 ENSRNOT00000014312
Gpm6a
glycoprotein m6a
chr6_-_140102325 7.13 ENSRNOT00000072238
AABR07065750.2

chr14_-_45165207 6.72 ENSRNOT00000002960
Klf3
Kruppel like factor 3
chr8_-_120446455 6.63 ENSRNOT00000085161
ENSRNOT00000042854
ENSRNOT00000037199
Arpp21
cAMP regulated phosphoprotein 21
chr5_+_34040258 6.48 ENSRNOT00000009758
Ggh
gamma-glutamyl hydrolase
chr14_-_45859908 6.44 ENSRNOT00000086994
Pgm2
phosphoglucomutase 2
chr7_+_18409147 6.36 ENSRNOT00000086336
ENSRNOT00000011849
Adamts10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr14_-_5378726 6.27 ENSRNOT00000002896
Lrrc8c
leucine rich repeat containing 8 family, member C
chr7_-_141001993 6.04 ENSRNOT00000092068
Fmnl3
formin-like 3
chr3_-_148312420 5.86 ENSRNOT00000047416
ENSRNOT00000081272
Bcl2l1
Bcl2-like 1
chr4_+_57378069 5.73 ENSRNOT00000080173
ENSRNOT00000011851
Nrf1
nuclear respiratory factor 1
chr6_-_102196138 5.65 ENSRNOT00000014132
Tmem229b
transmembrane protein 229B
chr2_-_30577218 5.60 ENSRNOT00000024674
Ocln
occludin
chr1_-_87147308 5.48 ENSRNOT00000027773
ENSRNOT00000089305
ENSRNOT00000090402
Actn4
actinin alpha 4
chrX_-_37705263 5.25 ENSRNOT00000043666
Map3k15
mitogen-activated protein kinase kinase kinase 15
chr7_-_118840634 5.04 ENSRNOT00000031568
Apol11a
apolipoprotein L 11a
chr5_-_153252021 5.01 ENSRNOT00000023221
Tmem50a
transmembrane protein 50A
chr17_+_9282675 4.99 ENSRNOT00000051702
H2afy
H2A histone family, member Y
chr3_-_80875817 4.74 ENSRNOT00000091265
Dgkz
diacylglycerol kinase zeta
chr1_+_220869805 4.70 ENSRNOT00000015962
Cfl1
cofilin 1
chr5_-_2803855 4.56 ENSRNOT00000009490
LOC297756
ribosomal protein S8-like
chr15_+_18399733 4.41 ENSRNOT00000061158
Fam107a
family with sequence similarity 107, member A
chr7_+_11301957 4.32 ENSRNOT00000027847
Tjp3
tight junction protein 3
chr1_-_204817080 4.28 ENSRNOT00000077956
Fam53b
family with sequence similarity 53, member B
chr3_-_148312791 4.19 ENSRNOT00000091419
Bcl2l1
Bcl2-like 1
chr7_-_23594133 4.15 ENSRNOT00000005746
Timp3
TIMP metallopeptidase inhibitor 3
chr7_-_12673659 4.12 ENSRNOT00000091650
ENSRNOT00000041277
ENSRNOT00000044865
Ptbp1
polypyrimidine tract binding protein 1
chr16_+_71738718 4.09 ENSRNOT00000022097
Plekha2
pleckstrin homology domain containing A2
chr6_-_138631997 3.93 ENSRNOT00000073304
AABR07065651.3

chr10_+_71278650 3.88 ENSRNOT00000092020
Synrg
synergin, gamma
chr4_+_77554269 3.80 ENSRNOT00000037248
Zfp282
zinc finger protein 282
chr1_+_219000844 3.71 ENSRNOT00000022486
Kmt5b
lysine methyltransferase 5B
chr8_-_111965889 3.49 ENSRNOT00000032376
Bfsp2
beaded filament structural protein 2
chr3_+_152909189 3.47 ENSRNOT00000066341
Tgif2
TGFB-induced factor homeobox 2
chr17_-_88140588 3.37 ENSRNOT00000006662
RGD1566369
similar to ribosomal protein S8
chr3_+_72134731 3.22 ENSRNOT00000083592
Ypel4
yippee-like 4
chr5_-_151473750 3.18 ENSRNOT00000011357
Tmem222
transmembrane protein 222
chr13_-_82753438 3.16 ENSRNOT00000075948
Atp1b1
ATPase Na+/K+ transporting subunit beta 1
chr1_-_262013619 3.10 ENSRNOT00000021278
Hps1
HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
chr3_-_10602672 3.04 ENSRNOT00000011648
Ncs1
neuronal calcium sensor 1
chr12_+_25093149 3.02 ENSRNOT00000050059
Eif4h
eukaryotic translation initiation factor 4H
chr1_-_228755866 2.99 ENSRNOT00000083283
Dtx4
deltex E3 ubiquitin ligase 4
chrX_+_31140960 2.96 ENSRNOT00000084395
ENSRNOT00000004494
Mospd2
motile sperm domain containing 2
chr6_+_126623015 2.92 ENSRNOT00000010672
Tmem251
transmembrane protein 251
chr15_-_18695133 2.88 ENSRNOT00000012271
Abhd6
abhydrolase domain containing 6
chr4_+_87293871 2.86 ENSRNOT00000090943
AABR07060628.1

chr8_+_116804451 2.70 ENSRNOT00000041402
Ip6k1
inositol hexakisphosphate kinase 1
chr1_+_203971152 2.61 ENSRNOT00000075540
Gpr26
G protein-coupled receptor 26
chr7_-_75288365 2.61 ENSRNOT00000036904
Ankrd46
ankyrin repeat domain 46
chr10_+_71217966 2.60 ENSRNOT00000076192
Hnf1b
HNF1 homeobox B
chr17_+_20619324 2.54 ENSRNOT00000079788
AABR07027235.1

chr8_-_28075514 2.49 ENSRNOT00000072851
Vps26b
VPS26 retromer complex component B
chr8_-_115358046 2.37 ENSRNOT00000017607
Grm2
glutamate metabotropic receptor 2
chr3_+_119805941 2.36 ENSRNOT00000018584
Adra2b
adrenoceptor alpha 2B
chr1_-_101054145 2.33 ENSRNOT00000082560
Prrg2
proline rich and Gla domain 2
chr6_+_10674371 2.24 ENSRNOT00000020337
Socs5
suppressor of cytokine signaling 5
chr7_-_73130740 2.10 ENSRNOT00000075584
9430069I07Rik
RIKEN cDNA 9430069I07 gene
chr8_+_19888667 2.09 ENSRNOT00000078593
Zfp317
zinc finger protein 317
chr8_-_21995806 1.98 ENSRNOT00000028034
S1pr2
sphingosine-1-phosphate receptor 2
chr18_+_29591611 1.91 ENSRNOT00000043271
Wdr55
WD repeat domain 55
chr13_-_97282299 1.82 ENSRNOT00000004244
Mixl1
Mix paired-like homeobox 1
chr17_-_10818835 1.77 ENSRNOT00000091046
Cplx2
complexin 2
chr19_-_38484611 1.76 ENSRNOT00000077960
Nfat5
nuclear factor of activated T-cells 5
chr16_+_64729221 1.73 ENSRNOT00000015297
Mak16
MAK16 homolog
chr14_+_113202419 1.58 ENSRNOT00000004764
Efemp1
EGF-containing fibulin-like extracellular matrix protein 1
chr5_+_148320438 1.35 ENSRNOT00000018742
Pef1
penta-EF hand domain containing 1
chr17_-_57816256 1.28 ENSRNOT00000051570
LOC103694120
isopentenyl-diphosphate delta-isomerase 2-like
chr5_+_171297850 1.21 ENSRNOT00000034284
Lrrc47
leucine rich repeat containing 47
chr3_-_10226286 1.20 ENSRNOT00000093627
Fubp3
far upstream element binding protein 3
chr1_+_274030978 0.94 ENSRNOT00000076387
Mxi1
MAX interactor 1, dimerization protein
chr4_+_57034675 0.92 ENSRNOT00000080223
Smo
smoothened, frizzled class receptor
chr10_+_110469290 0.89 ENSRNOT00000054919
Foxk2
forkhead box K2
chr4_-_85915099 0.88 ENSRNOT00000016182
Neurod6
neuronal differentiation 6
chr10_-_104718621 0.83 ENSRNOT00000011560
Fbf1
Fas binding factor 1
chr4_-_27755103 0.83 ENSRNOT00000012253
Fam133b
family with sequence similarity 133, member B
chr6_-_29999410 0.74 ENSRNOT00000075790
Sf3b6
splicing factor 3B, subunit 6
chr17_+_70684340 0.69 ENSRNOT00000051067
Pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr12_-_2540668 0.68 ENSRNOT00000001398
Snapc2
small nuclear RNA activating complex, polypeptide 2
chr17_+_26785029 0.63 ENSRNOT00000022065
Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr17_+_70684539 0.63 ENSRNOT00000025700
Pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr6_+_69971227 0.60 ENSRNOT00000075349
Foxg1
forkhead box G1
chr9_-_49950093 0.56 ENSRNOT00000023014
Fhl2
four and a half LIM domains 2
chr15_-_12513931 0.56 ENSRNOT00000010103
Atxn7
ataxin 7
chr8_+_128044084 0.55 ENSRNOT00000019106
Xylb
xylulokinase
chr6_+_93281408 0.54 ENSRNOT00000009610
Frmd6
FERM domain containing 6
chr5_-_169331163 0.24 ENSRNOT00000042301
Espn
espin
chr7_+_70292565 0.21 ENSRNOT00000073237
Avil
advillin
chr1_-_61686944 0.13 ENSRNOT00000059638
Vom1r23
vomeronasal 1 receptor 23
chr6_+_111642411 0.12 ENSRNOT00000016962
Adck1
aarF domain containing kinase 1
chr15_-_28733513 0.04 ENSRNOT00000078180
Sall2
spalt-like transcription factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Zkscan1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 20.6 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
3.9 15.8 GO:1903575 cornified envelope assembly(GO:1903575)
3.8 11.3 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
3.4 10.1 GO:1905218 cellular response to astaxanthin(GO:1905218)
3.2 9.5 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
2.6 7.9 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
2.6 10.4 GO:0032701 negative regulation of interleukin-18 production(GO:0032701)
2.2 12.9 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
2.0 16.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
2.0 12.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
1.7 5.0 GO:0033128 negative regulation of histone phosphorylation(GO:0033128) negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
1.6 4.7 GO:2000769 regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771)
1.4 11.4 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
1.4 11.2 GO:1903232 melanosome assembly(GO:1903232)
1.2 12.2 GO:0022614 membrane to membrane docking(GO:0022614)
1.1 5.5 GO:0048549 positive regulation of pinocytosis(GO:0048549)
1.1 11.6 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
1.1 3.2 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
1.0 4.1 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.0 3.0 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.9 2.6 GO:0061235 mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.7 2.9 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.6 2.4 GO:0035625 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.6 2.2 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.6 5.6 GO:0070673 response to interleukin-18(GO:0070673)
0.5 3.7 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.5 4.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.4 1.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.4 8.6 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.4 16.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 2.0 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 4.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.3 3.5 GO:0070307 lens fiber cell development(GO:0070307)
0.3 1.8 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.2 5.7 GO:0051593 response to folic acid(GO:0051593)
0.2 0.9 GO:0061113 positive regulation of hh target transcription factor activity(GO:0007228) pancreas morphogenesis(GO:0061113)
0.2 3.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 2.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.2 0.5 GO:0042732 D-xylose metabolic process(GO:0042732)
0.2 1.8 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.2 1.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 4.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 6.6 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 24.0 GO:0098656 anion transmembrane transport(GO:0098656)
0.1 1.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 4.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 1.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.6 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 2.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.1 0.9 GO:0021542 dentate gyrus development(GO:0021542)
0.1 3.8 GO:0010043 response to zinc ion(GO:0010043)
0.1 0.6 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.6 GO:0060347 heart trabecula formation(GO:0060347)
0.0 6.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 2.6 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 4.3 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 1.3 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 2.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 3.0 GO:0045921 positive regulation of exocytosis(GO:0045921)
0.0 0.7 GO:0001825 blastocyst formation(GO:0001825)
0.0 6.7 GO:1901653 cellular response to peptide(GO:1901653)
0.0 24.8 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.0 1.6 GO:0006006 glucose metabolic process(GO:0006006)
0.0 5.0 GO:0006897 endocytosis(GO:0006897)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 12.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
2.2 11.2 GO:0031085 BLOC-3 complex(GO:0031085)
1.4 10.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.8 7.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.6 5.0 GO:0001740 Barr body(GO:0001740)
0.6 6.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.4 1.8 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.4 12.2 GO:0030125 clathrin vesicle coat(GO:0030125)
0.4 3.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.4 5.5 GO:0031143 pseudopodium(GO:0031143)
0.4 16.7 GO:0044295 axonal growth cone(GO:0044295)
0.3 3.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 4.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 5.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 3.0 GO:0031045 dense core granule(GO:0031045)
0.1 18.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 3.7 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 16.6 GO:0005884 actin filament(GO:0005884)
0.1 1.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 2.5 GO:0030904 retromer complex(GO:0030904)
0.1 2.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 8.6 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.8 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 12.9 GO:0030426 growth cone(GO:0030426)
0.1 6.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 4.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 14.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 5.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0043296 apical junction complex(GO:0043296)
0.0 4.3 GO:0005923 bicellular tight junction(GO:0005923)
0.0 4.7 GO:0030027 lamellipodium(GO:0030027)
0.0 36.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 4.1 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 2.7 GO:0001650 fibrillar center(GO:0001650)
0.0 11.7 GO:0016604 nuclear body(GO:0016604)
0.0 1.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 26.0 GO:0005654 nucleoplasm(GO:0005654)
0.0 25.0 GO:0070062 extracellular exosome(GO:0070062)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 20.6 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
3.8 11.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
3.2 12.9 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.7 10.1 GO:0051434 BH3 domain binding(GO:0051434)
1.4 4.1 GO:0001069 regulatory region RNA binding(GO:0001069)
1.3 6.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.2 3.7 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.1 12.2 GO:0008131 primary amine oxidase activity(GO:0008131)
1.0 3.0 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.9 2.7 GO:0052724 inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.9 7.9 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.8 5.0 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.8 2.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.8 2.4 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.8 3.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.6 6.5 GO:0008242 omega peptidase activity(GO:0008242)
0.6 11.6 GO:0031996 thioesterase binding(GO:0031996)
0.5 6.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.4 1.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.4 4.7 GO:0001727 lipid kinase activity(GO:0001727)
0.4 18.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.3 3.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 1.3 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.3 8.6 GO:0004707 MAP kinase activity(GO:0004707)
0.3 6.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.3 2.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.2 3.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 2.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 4.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 3.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 5.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 1.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 24.8 GO:0001047 core promoter binding(GO:0001047)
0.1 17.7 GO:0015293 symporter activity(GO:0015293)
0.1 0.9 GO:0005113 patched binding(GO:0005113)
0.1 1.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 8.6 GO:0005178 integrin binding(GO:0005178)
0.1 13.9 GO:0019887 protein kinase regulator activity(GO:0019887)
0.1 9.0 GO:0005262 calcium channel activity(GO:0005262)
0.1 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 1.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 6.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 4.7 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 11.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 16.1 GO:0001159 core promoter proximal region DNA binding(GO:0001159)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 2.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 14.5 GO:0005198 structural molecule activity(GO:0005198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 32.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.8 16.8 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6 10.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4 16.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 11.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 7.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 2.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 5.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 8.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 5.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 4.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 4.8 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 5.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 2.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 17.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.7 12.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.5 20.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.5 10.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.5 16.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.4 11.4 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.4 5.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.3 4.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.3 6.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 5.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 12.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.2 7.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 3.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 3.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 2.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 8.6 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 6.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 3.0 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 2.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 4.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)