ISMARA results: Zic2

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zic2

Z-value: 0.95

Motif logo

Transcription factors associated with Zic2

Gene Symbol	Gene ID	Gene Info
Zic2 NCBI RGD Ensembl	ENSRNOG00000054879	Zic family member 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Zic2	rn6_v1_chr15_+_108908607_108908607	-0.11	5.2e-02	Click!

Activity profile of Zic2 motif

Sorted Z-values of Zic2 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_+_57855416 Show fit	20.40	ENSRNOT00000029608	Cpa2 NCBI RGD Ensembl Show fit	carboxypeptidase A2
chr6_+_139551751 Show fit	20.16	ENSRNOT00000081684	AABR07065699.2 NCBI RGD Ensembl Show fit
chr8_-_49308806 Show fit	19.82	ENSRNOT00000047291	Cd3e NCBI RGD Ensembl Show fit	CD3e molecule
chr5_-_160403373 Show fit	17.73	ENSRNOT00000018393	Ctrc NCBI RGD Ensembl Show fit	chymotrypsin C
chr1_+_279867034 Show fit	15.74	ENSRNOT00000024164	Pnliprp1 NCBI RGD Ensembl Show fit	pancreatic lipase-related protein 1
chr4_-_69268336 Show fit	15.51	ENSRNOT00000018042	Prss3b NCBI RGD Ensembl Show fit	protease, serine, 3B
chr3_+_17107861 Show fit	15.22	ENSRNOT00000043097	AABR07051563.1 NCBI RGD Ensembl Show fit
chr6_-_139719323 Show fit	15.01	ENSRNOT00000090133	AABR07065705.4 NCBI RGD Ensembl Show fit
chr3_+_16817051 Show fit	14.84	ENSRNOT00000071666	AABR07051550.1 NCBI RGD Ensembl Show fit
chr14_-_100217913 Show fit	14.79	ENSRNOT00000079167	Plek NCBI RGD Ensembl Show fit	pleckstrin
chr6_-_138772736 Show fit	14.60	ENSRNOT00000071492	AABR07065651.1 NCBI RGD Ensembl Show fit
chr6_-_138772894 Show fit	14.16	ENSRNOT00000080779	AABR07065651.1 NCBI RGD Ensembl Show fit
chr5_+_154522119 Show fit	14.16	ENSRNOT00000072618	E2f2 NCBI RGD Ensembl Show fit	E2F transcription factor 2
chr8_+_55603968 Show fit	12.89	ENSRNOT00000066848	Pou2af1 NCBI RGD Ensembl Show fit	POU class 2 associating factor 1
chr6_-_140216072 Show fit	12.45	ENSRNOT00000072365	AABR07065750.1 NCBI RGD Ensembl Show fit
chr17_-_34905117 Show fit	12.36	ENSRNOT00000088931	Irf4 NCBI RGD Ensembl Show fit	interferon regulatory factor 4
chr19_-_37907714 Show fit	12.28	ENSRNOT00000026361	Ctrl NCBI RGD Ensembl Show fit	chymotrypsin-like
chr1_-_215858034 Show fit	11.49	ENSRNOT00000027656	Ins2 NCBI RGD Ensembl Show fit	insulin 2
chr1_-_226791773 Show fit	11.09	ENSRNOT00000082482 ENSRNOT00000065376 ENSRNOT00000054812 ENSRNOT00000086669	LOC100911215 NCBI RGD Ensembl Show fit	T-cell surface glycoprotein CD5-like
chr6_-_45669148 Show fit	10.94	ENSRNOT00000010092	Rsad2 NCBI RGD Ensembl Show fit	radical S-adenosyl methionine domain containing 2
chr1_-_89543967 Show fit	10.81	ENSRNOT00000079631	Hpn NCBI RGD Ensembl Show fit	hepsin
chr17_-_42640221 Show fit	10.71	ENSRNOT00000018699	Cmah NCBI RGD Ensembl Show fit	cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr7_-_12741296 Show fit	10.45	ENSRNOT00000060648	Arhgap45 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 45
chr10_-_56506446 Show fit	10.21	ENSRNOT00000021357	Acap1 NCBI RGD Ensembl Show fit	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr17_-_15881327 Show fit	10.05	ENSRNOT00000022341	Ninj1 NCBI RGD Ensembl Show fit	ninjurin 1
chr10_+_103438303 Show fit	9.97	ENSRNOT00000085262	Cd300a NCBI RGD Ensembl Show fit	Cd300a molecule
chr17_-_43504604 Show fit	9.83	ENSRNOT00000083829 ENSRNOT00000066313	Slc17a1 NCBI RGD Ensembl Show fit	solute carrier family 17 member 1
chr14_+_77067503 Show fit	9.67	ENSRNOT00000085275	Slc2a9 NCBI RGD Ensembl Show fit	solute carrier family 2 member 9
chr9_-_52912293 Show fit	9.59	ENSRNOT00000005228	Slc40a1 NCBI RGD Ensembl Show fit	solute carrier family 40 member 1
chr2_-_203680083 Show fit	9.53	ENSRNOT00000021268	Cd2 NCBI RGD Ensembl Show fit	Cd2 molecule
chr2_-_123282214 Show fit	9.26	ENSRNOT00000021156	Ccna2 NCBI RGD Ensembl Show fit	cyclin A2
chr6_-_138744480 Show fit	9.15	ENSRNOT00000089387	AABR07065651.5 NCBI RGD Ensembl Show fit
chr10_-_15577977 Show fit	8.82	ENSRNOT00000052292	Hba-a3 NCBI RGD Ensembl Show fit	hemoglobin alpha, adult chain 3
chr6_+_129052503 Show fit	8.68	ENSRNOT00000044152	RGD1565462 NCBI RGD Ensembl Show fit	similar to BC049975 protein
chr2_-_123281856 Show fit	8.50	ENSRNOT00000079745	Ccna2 NCBI RGD Ensembl Show fit	cyclin A2
chrX_+_1311121 Show fit	8.35	ENSRNOT00000038909	Cfp NCBI RGD Ensembl Show fit	complement factor properdin
chr6_-_140418831 Show fit	8.31	ENSRNOT00000086301	AABR07065768.2 NCBI RGD Ensembl Show fit
chr15_-_29446332 Show fit	8.23	ENSRNOT00000082901	AABR07017634.1 NCBI RGD Ensembl Show fit
chrX_+_15273933 Show fit	8.16	ENSRNOT00000075082	LOC108348091 NCBI RGD Ensembl Show fit	erythroid transcription factor
chr1_-_261051498 Show fit	8.11	ENSRNOT00000071417	Arhgap19 NCBI RGD Ensembl Show fit	Rho GTPase activating protein 19
chr17_-_32783427 Show fit	8.04	ENSRNOT00000059921	Serpinb6b NCBI RGD Ensembl Show fit	serine (or cysteine) peptidase inhibitor, clade B, member 6b
chr6_-_139747579 Show fit	7.95	ENSRNOT00000075502	AABR07065705.3 NCBI RGD Ensembl Show fit
chr6_+_128048099 Show fit	7.95	ENSRNOT00000084685 ENSRNOT00000087017	LOC500712 NCBI RGD Ensembl Show fit	Ab1-233
chr2_+_209838869 Show fit	7.87	ENSRNOT00000092365	Kcna2 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily A member 2
chr15_+_32817343 Show fit	7.78	ENSRNOT00000073853	AABR07017902.1 NCBI RGD Ensembl Show fit
chr15_-_29987717 Show fit	7.72	ENSRNOT00000071501	AABR07017676.2 NCBI RGD Ensembl Show fit
chr6_-_138507294 Show fit	7.64	ENSRNOT00000078516	AABR07065640.1 NCBI RGD Ensembl Show fit
chr12_-_52452040 Show fit	7.49	ENSRNOT00000067453	Pole NCBI RGD Ensembl Show fit	DNA polymerase epsilon, catalytic subunit
chr9_+_16530074 Show fit	7.48	ENSRNOT00000091565	Ptcra NCBI RGD Ensembl Show fit	pre T-cell antigen receptor alpha
chrX_-_156891038 Show fit	7.42	ENSRNOT00000091495	Avpr2 NCBI RGD Ensembl Show fit	arginine vasopressin receptor 2
chr10_+_44271587 Show fit	7.35	ENSRNOT00000047700	Trim58 NCBI RGD Ensembl Show fit	tripartite motif-containing 58
chr6_-_99783047 Show fit	7.32	ENSRNOT00000009028	Sptb NCBI RGD Ensembl Show fit	spectrin, beta, erythrocytic
chr6_+_127927650 Show fit	7.31	ENSRNOT00000057271	LOC100909605 NCBI RGD Ensembl Show fit	serine protease inhibitor A3F-like
chr6_-_132608600 Show fit	7.31	ENSRNOT00000015855	Degs2 NCBI RGD Ensembl Show fit	delta(4)-desaturase, sphingolipid 2
chr10_+_57040267 Show fit	7.29	ENSRNOT00000026207	Arrb2 NCBI RGD Ensembl Show fit	arrestin, beta 2
chr10_-_90307658 Show fit	7.26	ENSRNOT00000092102	Slc4a1 NCBI RGD Ensembl Show fit	solute carrier family 4 member 1
chr8_+_33514042 Show fit	7.08	ENSRNOT00000081614 ENSRNOT00000081525	Kcnj1 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily J member 1
chr5_-_160620334 Show fit	7.06	ENSRNOT00000019171	Tmem51 NCBI RGD Ensembl Show fit	transmembrane protein 51
chr20_-_11620945 Show fit	7.04	ENSRNOT00000079725	Krtap12-2 NCBI RGD Ensembl Show fit	keratin associated protein 12-2
chr20_+_4020317 Show fit	7.01	ENSRNOT00000000526	RT1-DOb NCBI RGD Ensembl Show fit	RT1 class II, locus DOb
chr8_+_71822129 Show fit	7.00	ENSRNOT00000089147	Dapk2 NCBI RGD Ensembl Show fit	death-associated protein kinase 2
chr3_+_16590244 Show fit	6.99	ENSRNOT00000073229	AABR07051535.1 NCBI RGD Ensembl Show fit
chr16_+_74886719 Show fit	6.98	ENSRNOT00000089265	Atp7b NCBI RGD Ensembl Show fit	ATPase copper transporting beta
chr9_+_95285592 Show fit	6.96	ENSRNOT00000063853	Ugt1a5 NCBI RGD Ensembl Show fit	UDP glucuronosyltransferase family 1 member A5
chr16_+_20109200 Show fit	6.94	ENSRNOT00000079784	Jak3 NCBI RGD Ensembl Show fit	Janus kinase 3
chr7_-_78847974 Show fit	6.93	ENSRNOT00000006004	Dpys NCBI RGD Ensembl Show fit	dihydropyrimidinase
chr3_+_18706988 Show fit	6.86	ENSRNOT00000074650	AABR07051652.1 NCBI RGD Ensembl Show fit
chr11_+_71211768 Show fit	6.86	ENSRNOT00000079753	LOC100910650 NCBI RGD Ensembl Show fit	uncharacterized LOC100910650
chr16_+_19800463 Show fit	6.69	ENSRNOT00000023065	Ankle1 NCBI RGD Ensembl Show fit	ankyrin repeat and LEM domain containing 1
chr10_+_15697227 Show fit	6.54	ENSRNOT00000028008	Il9r NCBI RGD Ensembl Show fit	interleukin 9 receptor
chrX_+_70461718 Show fit	6.49	ENSRNOT00000078233 ENSRNOT00000003789	Kif4a NCBI RGD Ensembl Show fit	kinesin family member 4A
chr1_+_141986145 Show fit	6.48	ENSRNOT00000030914	Sema4b NCBI RGD Ensembl Show fit	semaphorin 4B
chr14_-_5378726 Show fit	6.46	ENSRNOT00000002896	Lrrc8c NCBI RGD Ensembl Show fit	leucine rich repeat containing 8 family, member C
chr6_-_138507135 Show fit	6.46	ENSRNOT00000071078	AABR07065640.1 NCBI RGD Ensembl Show fit
chr1_-_204605552 Show fit	6.44	ENSRNOT00000022904	Nkx1-2 NCBI RGD Ensembl Show fit	NK1 homeobox 2
chr16_-_7026540 Show fit	6.43	ENSRNOT00000051751	Itih1 NCBI RGD Ensembl Show fit	inter-alpha trypsin inhibitor, heavy chain 1
chr10_-_65692016 Show fit	6.40	ENSRNOT00000085074 ENSRNOT00000038690	Slc13a2 NCBI RGD Ensembl Show fit	solute carrier family 13 member 2
chr15_-_28104206 Show fit	6.35	ENSRNOT00000032536	Ang2 NCBI RGD Ensembl Show fit	angiogenin, ribonuclease A family, member 2
chr6_+_139523495 Show fit	6.31	ENSRNOT00000075467	AABR07065699.4 NCBI RGD Ensembl Show fit
chr20_+_4852671 Show fit	6.21	ENSRNOT00000001111	Lta NCBI RGD Ensembl Show fit	lymphotoxin alpha
chr4_-_122237754 Show fit	6.11	ENSRNOT00000029915	Chst13 NCBI RGD Ensembl Show fit	carbohydrate sulfotransferase 13
chr1_-_48360131 Show fit	6.06	ENSRNOT00000051927 ENSRNOT00000023116	Slc22a2 NCBI RGD Ensembl Show fit	solute carrier family 22 member 2
chr1_+_192233910 Show fit	6.06	ENSRNOT00000016418 ENSRNOT00000016442	Prkcb NCBI RGD Ensembl Show fit	protein kinase C, beta
chr17_+_43734461 Show fit	6.01	ENSRNOT00000072564	Hist1h1d NCBI RGD Ensembl Show fit	histone cluster 1, H1d
chr1_-_227932603 Show fit	6.01	ENSRNOT00000033795	Ms4a6a NCBI RGD Ensembl Show fit	membrane spanning 4-domains A6A
chr2_-_202816562 Show fit	6.00	ENSRNOT00000020401	Fam46c NCBI RGD Ensembl Show fit	family with sequence similarity 46, member C
chr10_-_87067456 Show fit	5.96	ENSRNOT00000014163	Ccr7 NCBI RGD Ensembl Show fit	C-C motif chemokine receptor 7
chr11_+_45462345 Show fit	5.92	ENSRNOT00000029420	Nit2 NCBI RGD Ensembl Show fit	nitrilase family, member 2
chr3_-_5975734 Show fit	5.91	ENSRNOT00000081376	Vav2 NCBI RGD Ensembl Show fit	vav guanine nucleotide exchange factor 2
chr10_-_56935141 Show fit	5.84	ENSRNOT00000025910	Alox12e NCBI RGD Ensembl Show fit	arachidonate 12-lipoxygenase, epidermal
chr11_-_60882379 Show fit	5.81	ENSRNOT00000002799	Cd200r1 NCBI RGD Ensembl Show fit	CD200 receptor 1
chr6_-_138536162 Show fit	5.77	ENSRNOT00000083031	AABR07065643.1 NCBI RGD Ensembl Show fit
chr11_+_54619129 Show fit	5.73	ENSRNOT00000059924	Trat1 NCBI RGD Ensembl Show fit	T cell receptor associated transmembrane adaptor 1
chrX_-_135342996 Show fit	5.70	ENSRNOT00000084848 ENSRNOT00000008503	Aifm1 NCBI RGD Ensembl Show fit	apoptosis inducing factor, mitochondria associated 1
chr2_-_219090874 Show fit	5.62	ENSRNOT00000019377	Vcam1 NCBI RGD Ensembl Show fit	vascular cell adhesion molecule 1
chr7_-_12634641 Show fit	5.54	ENSRNOT00000093132	Cfd NCBI RGD Ensembl Show fit	complement factor D
chr1_+_31967978 Show fit	5.53	ENSRNOT00000081471 ENSRNOT00000021532	Trip13 NCBI RGD Ensembl Show fit	thyroid hormone receptor interactor 13
chr6_+_144291974 Show fit	5.52	ENSRNOT00000035255	Ncapg2 NCBI RGD Ensembl Show fit	non-SMC condensin II complex, subunit G2
chr3_-_2727616 Show fit	5.50	ENSRNOT00000061904	C8g NCBI RGD Ensembl Show fit	complement C8 gamma chain
chr1_-_254671596 Show fit	5.47	ENSRNOT00000025450	Htr7 NCBI RGD Ensembl Show fit	5-hydroxytryptamine receptor 7
chr8_+_91368430 Show fit	5.44	ENSRNOT00000051612	Ttk NCBI RGD Ensembl Show fit	Ttk protein kinase
chr7_+_126939925 Show fit	5.44	ENSRNOT00000022746	Gramd4 NCBI RGD Ensembl Show fit	GRAM domain containing 4
chr17_-_9791781 Show fit	5.41	ENSRNOT00000090536	Rgs14 NCBI RGD Ensembl Show fit	regulator of G-protein signaling 14
chr20_+_4852496 Show fit	5.34	ENSRNOT00000088936	Lta NCBI RGD Ensembl Show fit	lymphotoxin alpha
chr1_-_164101578 Show fit	5.27	ENSRNOT00000022176	Uvrag NCBI RGD Ensembl Show fit	UV radiation resistance associated
chr6_+_123974798 Show fit	5.25	ENSRNOT00000075794	Kcnk13 NCBI RGD Ensembl Show fit	potassium two pore domain channel subfamily K member 13
chr1_-_88920291 Show fit	5.23	ENSRNOT00000028306	Kirrel2 NCBI RGD Ensembl Show fit	kin of IRRE like 2 (Drosophila)
chr13_-_41738622 Show fit	5.17	ENSRNOT00000004520 ENSRNOT00000084552	Actr3 NCBI RGD Ensembl Show fit	ARP3 actin related protein 3 homolog
chr5_+_34040258 Show fit	5.15	ENSRNOT00000009758	Ggh NCBI RGD Ensembl Show fit	gamma-glutamyl hydrolase
chr16_-_81434038 Show fit	5.11	ENSRNOT00000067508	Rasa3 NCBI RGD Ensembl Show fit	RAS p21 protein activator 3
chr13_+_82438697 Show fit	5.10	ENSRNOT00000003759	Selp NCBI RGD Ensembl Show fit	selectin P
chr15_+_31436302 Show fit	5.08	ENSRNOT00000071012	AABR07017825.2 NCBI RGD Ensembl Show fit
chr8_-_66893083 Show fit	5.06	ENSRNOT00000037028 ENSRNOT00000091755	Kif23 NCBI RGD Ensembl Show fit	kinesin family member 23
chr15_+_45422010 Show fit	5.04	ENSRNOT00000012231	Rnaseh2b NCBI RGD Ensembl Show fit	ribonuclease H2, subunit B
chr16_-_48692476 Show fit	4.97	ENSRNOT00000013118	Irf2 NCBI RGD Ensembl Show fit	interferon regulatory factor 2
chr9_+_98505259 Show fit	4.90	ENSRNOT00000051810	Erfe NCBI RGD Ensembl Show fit	erythroferrone
chr5_+_157801163 Show fit	4.88	ENSRNOT00000024160	Akr7a3 NCBI RGD Ensembl Show fit	aldo-keto reductase family 7 member A3
chr7_-_12635943 Show fit	4.85	ENSRNOT00000015029	Cfd NCBI RGD Ensembl Show fit	complement factor D
chr6_-_51498337 Show fit	4.79	ENSRNOT00000012487	Pik3cg NCBI RGD Ensembl Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr4_+_96252798 Show fit	4.78	ENSRNOT00000008947	RGD1560028 NCBI RGD Ensembl Show fit	similar to RIKEN cDNA C130060K24 gene
chr16_+_9023387 Show fit	4.77	ENSRNOT00000067761	RGD1561145 NCBI RGD Ensembl Show fit	similar to novel protein
chr7_-_12899004 Show fit	4.77	ENSRNOT00000011086	Gzmm NCBI RGD Ensembl Show fit	granzyme M
chr7_-_12646960 Show fit	4.77	ENSRNOT00000014687	Prtn3 NCBI RGD Ensembl Show fit	proteinase 3
chr12_+_30198822 Show fit	4.74	ENSRNOT00000041645	Gusb NCBI RGD Ensembl Show fit	glucuronidase, beta
chr15_-_27733785 Show fit	4.71	ENSRNOT00000029488	Ccnb1ip1 NCBI RGD Ensembl Show fit	cyclin B1 interacting protein 1
chr3_-_5976244 Show fit	4.67	ENSRNOT00000009893	Vav2 NCBI RGD Ensembl Show fit	vav guanine nucleotide exchange factor 2
chr11_-_70499200 Show fit	4.66	ENSRNOT00000002439	Slc12a8 NCBI RGD Ensembl Show fit	solute carrier family 12, member 8
chr3_+_2591331 Show fit	4.65	ENSRNOT00000017466	Sapcd2 NCBI RGD Ensembl Show fit	suppressor APC domain containing 2
chr10_+_18996523 Show fit	4.64	ENSRNOT00000046135	Lcp2 NCBI RGD Ensembl Show fit	lymphocyte cytosolic protein 2
chr1_+_21748261 Show fit	4.57	ENSRNOT00000019519	Enpp1 NCBI RGD Ensembl Show fit	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr10_-_82374171 Show fit	4.56	ENSRNOT00000032693	Eme1 NCBI RGD Ensembl Show fit	essential meiotic structure-specific endonuclease 1
chr17_-_9792007 Show fit	4.55	ENSRNOT00000021596	Rgs14 NCBI RGD Ensembl Show fit	regulator of G-protein signaling 14
chr10_-_70337532 Show fit	4.53	ENSRNOT00000055963	Slfn13 NCBI RGD Ensembl Show fit	schlafen family member 13
chr10_+_59529785 Show fit	4.51	ENSRNOT00000064840 ENSRNOT00000065181	Atp2a3 NCBI RGD Ensembl Show fit	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr8_-_49573742 Show fit	4.46	ENSRNOT00000021926	Il10ra NCBI RGD Ensembl Show fit	interleukin 10 receptor subunit alpha
chr7_-_130128589 Show fit	4.45	ENSRNOT00000079777 ENSRNOT00000009325	Mapk11 NCBI RGD Ensembl Show fit	mitogen-activated protein kinase 11
chr15_-_29976615 Show fit	4.45	ENSRNOT00000060396	AABR07017676.1 NCBI RGD Ensembl Show fit
chr15_-_44627765 Show fit	4.45	ENSRNOT00000058887	Dock5 NCBI RGD Ensembl Show fit	dedicator of cytokinesis 5
chr2_+_240396152 Show fit	4.44	ENSRNOT00000034565	Cenpe NCBI RGD Ensembl Show fit	centromere protein E
chr12_-_17322608 Show fit	4.43	ENSRNOT00000033038	LOC102546864 NCBI RGD Ensembl Show fit	uncharacterized LOC102546864
chr3_+_81283137 Show fit	4.42	ENSRNOT00000008986 ENSRNOT00000086217	Pex16 NCBI RGD Ensembl Show fit	peroxisomal biogenesis factor 16
chr1_-_48559162 Show fit	4.34	ENSRNOT00000080352	Plg NCBI RGD Ensembl Show fit	plasminogen
chr9_+_10956056 Show fit	4.32	ENSRNOT00000073930	Plin5 NCBI RGD Ensembl Show fit	perilipin 5
chr5_-_155204456 Show fit	4.30	ENSRNOT00000089574	Ephb2 NCBI RGD Ensembl Show fit	Eph receptor B2
chr8_+_91368111 Show fit	4.30	ENSRNOT00000083151	Ttk NCBI RGD Ensembl Show fit	Ttk protein kinase
chrX_-_72078551 Show fit	4.27	ENSRNOT00000076978	Rps4x NCBI RGD Ensembl Show fit	ribosomal protein S4, X-linked
chr18_+_12056113 Show fit	4.27	ENSRNOT00000038450	Dsg4 NCBI RGD Ensembl Show fit	desmoglein 4
chr2_-_104830898 Show fit	4.23	ENSRNOT00000050440	Hps3 NCBI RGD Ensembl Show fit	Hermansky-Pudlak syndrome 3
chr11_-_61499557 Show fit	4.23	ENSRNOT00000046208	Usf3 NCBI RGD Ensembl Show fit	upstream transcription factor family member 3
chr16_+_74752655 Show fit	4.21	ENSRNOT00000029266	Ckap2 NCBI RGD Ensembl Show fit	cytoskeleton associated protein 2
chr3_-_176744377 Show fit	4.21	ENSRNOT00000017787	Helz2 NCBI RGD Ensembl Show fit	helicase with zinc finger 2, transcriptional coactivator
chr3_+_159368273 Show fit	4.21	ENSRNOT00000041688	Sgk2 NCBI RGD Ensembl Show fit	serum/glucocorticoid regulated kinase 2
chr8_-_6061837 Show fit	4.14	ENSRNOT00000007702	Birc3 NCBI RGD Ensembl Show fit	baculoviral IAP repeat-containing 3
chr7_+_141258584 Show fit	4.11	ENSRNOT00000083570	Aqp6 NCBI RGD Ensembl Show fit	aquaporin 6
chr2_+_263895241 Show fit	4.11	ENSRNOT00000014126 ENSRNOT00000014034	Ptger3 NCBI RGD Ensembl Show fit	prostaglandin E receptor 3
chr20_+_40778927 Show fit	4.08	ENSRNOT00000001081	Smpdl3a NCBI RGD Ensembl Show fit	sphingomyelin phosphodiesterase, acid-like 3A
chr2_+_209839299 Show fit	4.06	ENSRNOT00000092450	Kcna2 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily A member 2
chr8_-_120446455 Show fit	4.03	ENSRNOT00000085161 ENSRNOT00000042854 ENSRNOT00000037199	Arpp21 NCBI RGD Ensembl Show fit	cAMP regulated phosphoprotein 21
chr12_-_22478752 Show fit	4.00	ENSRNOT00000089392 ENSRNOT00000086915	Ache NCBI RGD Ensembl Show fit	acetylcholinesterase
chr5_-_169630340 Show fit	4.00	ENSRNOT00000087043	Kcnab2 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr11_-_32508420 Show fit	3.99	ENSRNOT00000002717	Kcne1 NCBI RGD Ensembl Show fit	potassium voltage-gated channel subfamily E regulatory subunit 1
chr3_+_5624506 Show fit	3.98	ENSRNOT00000036995	Adamtsl2 NCBI RGD Ensembl Show fit	ADAMTS-like 2
chr1_-_254671778 Show fit	3.98	ENSRNOT00000025493	Htr7 NCBI RGD Ensembl Show fit	5-hydroxytryptamine receptor 7
chr10_-_87510629 Show fit	3.96	ENSRNOT00000084197	Krtap1-3 NCBI RGD Ensembl Show fit	keratin associated protein 1-3
chr4_+_62220736 Show fit	3.91	ENSRNOT00000086377	Cald1 NCBI RGD Ensembl Show fit	caldesmon 1
chr10_-_87535438 Show fit	3.90	ENSRNOT00000086873	Krtap2-4 NCBI RGD Ensembl Show fit	keratin associated protein 2-4
chr11_+_47260641 Show fit	3.88	ENSRNOT00000078856	Nfkbiz NCBI RGD Ensembl Show fit	NFKB inhibitor zeta
chr16_-_48981980 Show fit	3.88	ENSRNOT00000014235	Acsl1 NCBI RGD Ensembl Show fit	acyl-CoA synthetase long-chain family member 1
chrX_-_23187341 Show fit	3.87	ENSRNOT00000000180	Alas2 NCBI RGD Ensembl Show fit	5'-aminolevulinate synthase 2
chr1_+_282567674 Show fit	3.85	ENSRNOT00000090543	Ces2i NCBI RGD Ensembl Show fit	carboxylesterase 2I
chr10_+_86950557 Show fit	3.83	ENSRNOT00000014153	Igfbp4 NCBI RGD Ensembl Show fit	insulin-like growth factor binding protein 4
chr14_+_17228856 Show fit	3.81	ENSRNOT00000003082	Cxcl9 NCBI RGD Ensembl Show fit	C-X-C motif chemokine ligand 9
chr10_-_57739109 Show fit	3.79	ENSRNOT00000082171	Nlrp1a NCBI RGD Ensembl Show fit	NLR family, pyrin domain containing 1A
chr19_+_15139920 Show fit	3.76	ENSRNOT00000074479 ENSRNOT00000020775	Ces1f NCBI RGD Ensembl Show fit	carboxylesterase 1F
chr5_+_126668689 Show fit	3.76	ENSRNOT00000036072	Cyb5rl NCBI RGD Ensembl Show fit	cytochrome b5 reductase-like
chr3_+_161236898 Show fit	3.72	ENSRNOT00000082303 ENSRNOT00000020323	Ube2c NCBI RGD Ensembl Show fit	ubiquitin-conjugating enzyme E2C
chr12_-_41625403 Show fit	3.71	ENSRNOT00000001876	Sds NCBI RGD Ensembl Show fit	serine dehydratase
chr15_+_31164401 Show fit	3.71	ENSRNOT00000084286	AABR07017798.1 NCBI RGD Ensembl Show fit
chr7_-_3342491 Show fit	3.71	ENSRNOT00000081756	Rdh5 NCBI RGD Ensembl Show fit	retinol dehydrogenase 5
chr8_+_48382121 Show fit	3.70	ENSRNOT00000008685	Thy1 NCBI RGD Ensembl Show fit	Thy-1 cell surface antigen
chr12_+_52452273 Show fit	3.69	ENSRNOT00000056680 ENSRNOT00000088381	Pxmp2 NCBI RGD Ensembl Show fit	peroxisomal membrane protein 2
chr10_+_4313100 Show fit	3.68	ENSRNOT00000074487	LOC100911685 NCBI RGD Ensembl Show fit	eukaryotic peptide chain release factor GTP-binding subunit ERF3B-like
chr1_+_221596148 Show fit	3.66	ENSRNOT00000028536	Gpha2 NCBI RGD Ensembl Show fit	glycoprotein hormone alpha 2
chr10_-_87261717 Show fit	3.64	ENSRNOT00000015740	Krt27 NCBI RGD Ensembl Show fit	keratin 27
chr19_-_9843673 Show fit	3.63	ENSRNOT00000015795	Gins3 NCBI RGD Ensembl Show fit	GINS complex subunit 3
chr13_-_100450209 Show fit	3.63	ENSRNOT00000090712	Lbr NCBI RGD Ensembl Show fit	lamin B receptor
chr8_+_59507990 Show fit	3.62	ENSRNOT00000018003	Hykk NCBI RGD Ensembl Show fit	hydroxylysine kinase
chr8_+_5768811 Show fit	3.62	ENSRNOT00000013936	Mmp8 NCBI RGD Ensembl Show fit	matrix metallopeptidase 8
chr14_-_81472952 Show fit	3.61	ENSRNOT00000058111	Sh3bp2 NCBI RGD Ensembl Show fit	SH3-domain binding protein 2
chr10_-_64915148 Show fit	3.55	ENSRNOT00000048543	Sez6 NCBI RGD Ensembl Show fit	seizure related 6 homolog
chr5_-_136053210 Show fit	3.53	ENSRNOT00000025903	Kif2c NCBI RGD Ensembl Show fit	kinesin family member 2C
chr10_-_2229493 Show fit	3.51	ENSRNOT00000047732	LOC688899 NCBI RGD Ensembl Show fit	similar to 40S ribosomal protein S19
chr7_-_123892429 Show fit	3.50	ENSRNOT00000037681	Nfam1 NCBI RGD Ensembl Show fit	NFAT activating protein with ITAM motif 1
chr6_-_127337791 Show fit	3.48	ENSRNOT00000032015	Ifi27l2b NCBI RGD Ensembl Show fit	interferon, alpha-inducible protein 27 like 2B
chr2_-_30577218 Show fit	3.48	ENSRNOT00000024674	Ocln NCBI RGD Ensembl Show fit	occludin
chr1_-_256813711 Show fit	3.48	ENSRNOT00000021055	Rbp4 NCBI RGD Ensembl Show fit	retinol binding protein 4
chr5_-_68139199 Show fit	3.48	ENSRNOT00000009987	Plppr1 NCBI RGD Ensembl Show fit	phospholipid phosphatase related 1
chr6_-_129010271 Show fit	3.47	ENSRNOT00000075378	Serpina10 NCBI RGD Ensembl Show fit	serpin family A member 10
chr1_+_83573032 Show fit	3.46	ENSRNOT00000083650	AC142154.2 NCBI RGD Ensembl Show fit
chr8_-_75995371 Show fit	3.45	ENSRNOT00000014014	Foxb1 NCBI RGD Ensembl Show fit	forkhead box B1

Network of associatons between targets according to the STRING database.

First level regulatory network of Zic2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.1	12.4	GO:0045082	positive regulation of interleukin-10 biosynthetic process(GO:0045082)
3.9	11.6	GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
3.8	11.5	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
3.7	14.8	GO:0070560	protein secretion by platelet(GO:0070560)
3.6	10.9	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
3.6	10.8	GO:0034769	basement membrane disassembly(GO:0034769)
3.3	10.0	GO:0060101	negative regulation of phagocytosis, engulfment(GO:0060101) negative regulation of eosinophil activation(GO:1902567) negative regulation of eosinophil migration(GO:2000417)
3.3	10.0	GO:0010070	zygote asymmetric cell division(GO:0010070)
3.3	19.8	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
3.2	9.7	GO:1905132	metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
3.2	9.5	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
3.1	18.5	GO:0071314	cellular response to cocaine(GO:0071314)
2.4	7.3	GO:0006667	sphinganine metabolic process(GO:0006667)
2.4	9.6	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
2.4	7.1	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
2.3	7.0	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
2.3	7.0	GO:2000424	regulation of eosinophil chemotaxis(GO:2000422) positive regulation of eosinophil chemotaxis(GO:2000424)
2.3	7.0	GO:0015680	intracellular copper ion transport(GO:0015680)
2.3	6.9	GO:0045210	negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
2.3	9.1	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
2.2	8.7	GO:0002184	cytoplasmic translational termination(GO:0002184)
2.1	10.7	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
2.1	14.8	GO:0051256	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
2.0	8.2	GO:0030221	basophil differentiation(GO:0030221)
2.0	6.1	GO:0035408	histone H3-T6 phosphorylation(GO:0035408)
2.0	11.9	GO:0021633	optic nerve structural organization(GO:0021633)
2.0	9.9	GO:0019860	uracil metabolic process(GO:0019860)
1.9	7.5	GO:0006272	leading strand elongation(GO:0006272)
1.8	7.3	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
1.7	10.5	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
1.7	5.2	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344) regulation of bleb assembly(GO:1904170)
1.6	4.9	GO:0009407	toxin catabolic process(GO:0009407) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) secondary metabolite catabolic process(GO:0090487) organic heteropentacyclic compound catabolic process(GO:1901377)
1.5	4.6	GO:0030505	inorganic diphosphate transport(GO:0030505)
1.5	4.4	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
1.5	7.3	GO:0010037	response to carbon dioxide(GO:0010037)
1.4	7.2	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
1.4	4.3	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
1.4	4.1	GO:0001698	gastrin-induced gastric acid secretion(GO:0001698) positive regulation of actin filament-based movement(GO:1903116) negative regulation of forebrain neuron differentiation(GO:2000978)
1.3	6.7	GO:0045950	negative regulation of mitotic recombination(GO:0045950)
1.3	5.3	GO:0097680	maintenance of Golgi location(GO:0051684) double-strand break repair via classical nonhomologous end joining(GO:0097680)
1.3	6.4	GO:0071104	response to interleukin-9(GO:0071104)
1.2	3.7	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.2	3.5	GO:0046865	isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
1.1	4.6	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
1.1	5.7	GO:1904045	cellular response to aldosterone(GO:1904045)
1.1	3.3	GO:0010979	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) calcitriol biosynthetic process from calciol(GO:0036378) vitamin D catabolic process(GO:0042369) positive regulation of response to alcohol(GO:1901421)
1.1	4.3	GO:0099545	trans-synaptic signaling by trans-synaptic complex(GO:0099545)
1.0	19.5	GO:0046415	urate metabolic process(GO:0046415)
1.0	3.0	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
1.0	3.0	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
1.0	3.0	GO:0046968	cytosol to ER transport(GO:0046967) peptide antigen transport(GO:0046968)
1.0	5.9	GO:0006528	asparagine metabolic process(GO:0006528)
1.0	2.9	GO:0009946	inhibition of neuroepithelial cell differentiation(GO:0002085) proximal/distal axis specification(GO:0009946)
1.0	2.9	GO:1905168	positive regulation of double-strand break repair via homologous recombination(GO:1905168)
1.0	3.9	GO:1901423	response to benzene(GO:1901423)
1.0	9.5	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
1.0	2.9	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.9	3.7	GO:0010993	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.9	3.7	GO:0006565	L-serine catabolic process(GO:0006565)
0.9	4.5	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.9	4.4	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.9	2.6	GO:0046356	coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.9	3.5	GO:0061373	mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.9	6.0	GO:0007144	female meiosis I(GO:0007144)
0.8	5.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.8	3.4	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.8	7.0	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.8	10.0	GO:0060033	anatomical structure regression(GO:0060033)
0.8	6.1	GO:0015871	choline transport(GO:0015871)
0.8	6.0	GO:0016584	nucleosome positioning(GO:0016584)
0.7	4.4	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.7	2.2	GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.7	0.7	GO:0006649	phospholipid transfer to membrane(GO:0006649)
0.7	5.7	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.7	7.8	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.7	5.6	GO:0022614	membrane to membrane docking(GO:0022614)
0.7	2.8	GO:1904253	lipid transport involved in lipid storage(GO:0010877) positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.7	7.5	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.7	2.0	GO:0006083	acetate metabolic process(GO:0006083) propionate metabolic process(GO:0019541)
0.7	2.0	GO:1904569	regulation of selenocysteine incorporation(GO:1904569)
0.6	2.6	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.6	2.6	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.6	3.8	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.6	2.4	GO:1902896	terminal web assembly(GO:1902896)
0.6	1.8	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.6	1.8	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.6	8.8	GO:0015671	oxygen transport(GO:0015671)
0.6	1.8	GO:0036451	cap mRNA methylation(GO:0036451)
0.6	5.8	GO:0019372	lipoxygenase pathway(GO:0019372)
0.6	4.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.6	2.9	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.6	3.4	GO:0097117	guanylate kinase-associated protein clustering(GO:0097117)
0.6	3.4	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.5	2.6	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.5	2.6	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.5	2.5	GO:0060539	diaphragm development(GO:0060539)
0.5	6.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.5	3.5	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.5	4.0	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.5	4.0	GO:0060481	lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.5	1.5	GO:0090669	telomerase RNA stabilization(GO:0090669)
0.5	1.5	GO:0006431	methionyl-tRNA aminoacylation(GO:0006431)
0.5	3.4	GO:0071373	cellular response to luteinizing hormone stimulus(GO:0071373)
0.5	3.4	GO:0006477	protein sulfation(GO:0006477)
0.5	3.4	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.5	2.4	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.5	4.2	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.5	4.1	GO:0051026	chiasma assembly(GO:0051026)
0.4	4.0	GO:0070995	NADPH oxidation(GO:0070995)
0.4	3.9	GO:0034201	response to oleic acid(GO:0034201)
0.4	4.1	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.4	5.3	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.4	1.2	GO:1904760	myofibroblast differentiation(GO:0036446) cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939) regulation of myofibroblast differentiation(GO:1904760)
0.4	2.4	GO:0033504	floor plate development(GO:0033504)
0.4	10.3	GO:0019835	cytolysis(GO:0019835)
0.4	3.5	GO:0070673	response to interleukin-18(GO:0070673)
0.4	2.6	GO:0003164	His-Purkinje system development(GO:0003164)
0.4	1.1	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.4	2.9	GO:1903232	melanosome assembly(GO:1903232)
0.4	10.5	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.4	1.8	GO:1902732	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145) positive regulation of chondrocyte proliferation(GO:1902732)
0.4	1.8	GO:0018101	protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4	12.0	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.3	1.0	GO:0035793	negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling(GO:0060683) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) embryonic lung development(GO:1990401) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.3	1.4	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.3	1.0	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3	2.4	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.3	1.0	GO:0061188	negative regulation of chromatin silencing at rDNA(GO:0061188)
0.3	1.0	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.3	1.6	GO:0060005	vestibular reflex(GO:0060005)
0.3	3.3	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
0.3	2.2	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.3	0.9	GO:1903796	negative regulation of inorganic anion transmembrane transport(GO:1903796) negative regulation of chloride transport(GO:2001226)
0.3	1.9	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.3	1.2	GO:1902869	regulation of amacrine cell differentiation(GO:1902869)
0.3	2.8	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.3	0.6	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.3	2.4	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.3	2.0	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.3	0.9	GO:1903769	negative regulation of cell proliferation in bone marrow(GO:1903769)
0.3	5.1	GO:0006541	glutamine metabolic process(GO:0006541)
0.3	1.7	GO:1902416	positive regulation of mRNA binding(GO:1902416)
0.3	5.0	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.3	5.5	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.3	2.5	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.3	3.8	GO:0050930	positive regulation of cAMP-mediated signaling(GO:0043950) induction of positive chemotaxis(GO:0050930)
0.3	3.8	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.3	3.7	GO:0036065	fucosylation(GO:0036065)
0.3	4.4	GO:1902358	sulfate transport(GO:0008272) sulfate transmembrane transport(GO:1902358)
0.3	7.7	GO:0009225	nucleotide-sugar metabolic process(GO:0009225)
0.3	0.5	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2	0.5	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2	5.1	GO:2000193	positive regulation of fatty acid transport(GO:2000193)
0.2	1.4	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.2	1.4	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.2	4.6	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.2	1.8	GO:0014022	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2	1.5	GO:0006868	glutamine transport(GO:0006868)
0.2	2.0	GO:0090527	actin filament reorganization(GO:0090527)
0.2	8.9	GO:0006778	porphyrin-containing compound metabolic process(GO:0006778)
0.2	0.8	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2	0.8	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.2	1.5	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.2	1.3	GO:0048318	axial mesoderm development(GO:0048318)
0.2	3.4	GO:0006625	protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.2	0.5	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.2	0.7	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
0.2	1.5	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.2	1.7	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2	0.8	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2	1.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.2	0.7	GO:0097116	postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.2	0.6	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.2	1.3	GO:0000012	single strand break repair(GO:0000012)
0.2	2.2	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2	1.5	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.2	6.1	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.2	2.4	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.2	2.9	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2	2.0	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.3	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1	2.4	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.1	1.6	GO:0030903	notochord development(GO:0030903)
0.1	2.2	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.1	0.9	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.1	2.5	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.1	4.5	GO:1905144	acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1	3.0	GO:1900048	positive regulation of blood coagulation(GO:0030194) positive regulation of hemostasis(GO:1900048)
0.1	0.4	GO:0021918	pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) positive regulation of glucagon secretion(GO:0070094) sensory neuron migration(GO:1904937)
0.1	3.6	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.1	0.4	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.1	1.9	GO:0006677	glycosylceramide metabolic process(GO:0006677)
0.1	11.8	GO:0031016	pancreas development(GO:0031016)
0.1	3.5	GO:0060074	synapse maturation(GO:0060074)
0.1	4.2	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.1	1.0	GO:0010649	regulation of cell communication by electrical coupling(GO:0010649)
0.1	1.6	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.8	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	2.3	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.6	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	8.0	GO:0045576	mast cell activation(GO:0045576)
0.1	1.9	GO:0046037	GMP metabolic process(GO:0046037)
0.1	1.3	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.1	1.3	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.1	6.2	GO:0034605	cellular response to heat(GO:0034605)
0.1	0.4	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1	0.4	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
0.1	0.4	GO:0006824	cobalt ion transport(GO:0006824)
0.1	1.5	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	2.6	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
0.1	7.9	GO:1902476	chloride transmembrane transport(GO:1902476)
0.1	1.5	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	9.4	GO:0007586	digestion(GO:0007586)
0.1	1.0	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1	0.5	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.1	0.7	GO:0006021	inositol biosynthetic process(GO:0006021)
0.1	0.7	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1	0.4	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
0.1	0.9	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1	1.1	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1	5.0	GO:0046849	bone remodeling(GO:0046849)
0.1	2.4	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.1	0.8	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.1	0.2	GO:0035928	rRNA import into mitochondrion(GO:0035928)
0.1	7.5	GO:0090501	RNA phosphodiester bond hydrolysis(GO:0090501)
0.1	4.2	GO:0032411	positive regulation of transporter activity(GO:0032411)
0.1	0.9	GO:0006833	water transport(GO:0006833)
0.1	1.2	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1	0.2	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.1	0.9	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1	0.7	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.8	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1	0.5	GO:0007097	nuclear migration(GO:0007097)
0.1	1.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1	1.3	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.1	4.2	GO:0043473	pigmentation(GO:0043473)
0.1	12.5	GO:0010951	negative regulation of endopeptidase activity(GO:0010951)
0.0	0.8	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	3.0	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0	3.3	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	4.3	GO:0045727	positive regulation of translation(GO:0045727)
0.0	1.6	GO:0002763	positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0	1.1	GO:0006953	acute-phase response(GO:0006953)
0.0	0.2	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	8.6	GO:0006898	receptor-mediated endocytosis(GO:0006898)
0.0	1.7	GO:0030819	positive regulation of cAMP biosynthetic process(GO:0030819)
0.0	1.4	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.4	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	1.7	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	3.4	GO:0006334	nucleosome assembly(GO:0006334)
0.0	0.5	GO:0018195	peptidyl-arginine modification(GO:0018195)
0.0	0.5	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	2.4	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	0.2	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	1.1	GO:0002181	cytoplasmic translation(GO:0002181)
0.0	0.5	GO:0030857	negative regulation of epithelial cell differentiation(GO:0030857)
0.0	0.8	GO:0015914	phospholipid transport(GO:0015914)
0.0	1.9	GO:0042752	regulation of circadian rhythm(GO:0042752)
0.0	1.4	GO:2001022	positive regulation of response to DNA damage stimulus(GO:2001022)
0.0	0.5	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.4	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.3	GO:2000279	negative regulation of DNA biosynthetic process(GO:2000279)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.9	17.8	GO:0097124	cyclin A2-CDK2 complex(GO:0097124)
2.5	19.8	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
2.2	8.7	GO:0018444	translation release factor complex(GO:0018444)
1.6	4.8	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.5	7.5	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
1.4	5.6	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
1.3	5.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
1.3	5.1	GO:0097149	centralspindlin complex(GO:0097149)
1.3	5.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
1.2	6.2	GO:0048476	Holliday junction resolvase complex(GO:0048476)
1.2	4.6	GO:0036398	TCR signalosome(GO:0036398)
1.1	4.3	GO:0044279	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
1.0	15.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
1.0	5.8	GO:0030478	actin cap(GO:0030478)
0.9	3.4	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.8	4.1	GO:1990769	proximal neuron projection(GO:1990769)
0.8	8.8	GO:0005833	hemoglobin complex(GO:0005833)
0.8	59.7	GO:0045095	keratin filament(GO:0045095)
0.8	2.4	GO:0005760	gamma DNA polymerase complex(GO:0005760)
0.8	3.8	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.7	7.3	GO:0008091	spectrin(GO:0008091) spectrin-associated cytoskeleton(GO:0014731)
0.7	7.2	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.7	5.5	GO:0000796	condensin complex(GO:0000796)
0.7	18.4	GO:0000788	nuclear nucleosome(GO:0000788)
0.6	2.6	GO:1990005	granular vesicle(GO:1990005)
0.6	2.9	GO:0031085	BLOC-3 complex(GO:0031085)
0.6	5.7	GO:0042101	T cell receptor complex(GO:0042101)
0.5	1.6	GO:0071149	TEAD-2-YAP complex(GO:0071149)
0.5	10.3	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.5	3.0	GO:0042584	chromaffin granule membrane(GO:0042584) dendritic spine neck(GO:0044326)
0.5	1.4	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.5	13.4	GO:0042629	mast cell granule(GO:0042629)
0.5	11.8	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.4	7.0	GO:0042613	MHC class II protein complex(GO:0042613)
0.4	5.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.4	8.1	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.4	3.0	GO:0042825	TAP complex(GO:0042825)
0.4	1.9	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.4	2.7	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.4	5.9	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.4	4.4	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.3	5.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3	2.8	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.3	1.1	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.3	4.2	GO:0031082	BLOC complex(GO:0031082)
0.3	1.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.3	3.3	GO:0031983	vesicle lumen(GO:0031983)
0.2	7.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.2	10.0	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.2	4.1	GO:0005680	anaphase-promoting complex(GO:0005680)
0.2	1.6	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.2	0.6	GO:0097427	microtubule bundle(GO:0097427)
0.2	22.5	GO:0072562	blood microparticle(GO:0072562)
0.2	4.2	GO:0097386	glial cell projection(GO:0097386)
0.2	0.5	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	3.5	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	1.1	GO:0070449	elongin complex(GO:0070449)
0.1	3.5	GO:0097440	apical dendrite(GO:0097440)
0.1	2.4	GO:0032433	filopodium tip(GO:0032433)
0.1	3.5	GO:0035371	microtubule plus-end(GO:0035371)
0.1	5.9	GO:0045171	intercellular bridge(GO:0045171)
0.1	1.8	GO:0042581	specific granule(GO:0042581)
0.1	8.7	GO:0032587	ruffle membrane(GO:0032587)
0.1	10.4	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	3.6	GO:0016235	aggresome(GO:0016235)
0.1	0.5	GO:0097361	CIA complex(GO:0097361)
0.1	1.9	GO:0045120	pronucleus(GO:0045120)
0.1	9.8	GO:0016605	PML body(GO:0016605)
0.1	3.2	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	11.1	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.1	5.3	GO:0045335	phagocytic vesicle(GO:0045335)
0.1	5.7	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.1	7.4	GO:0030139	endocytic vesicle(GO:0030139)
0.1	12.0	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.1	1.0	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	4.3	GO:0005844	polysome(GO:0005844)
0.1	0.8	GO:0042555	MCM complex(GO:0042555)
0.1	0.5	GO:0097208	alveolar lamellar body(GO:0097208)
0.1	2.6	GO:0016328	lateral plasma membrane(GO:0016328)
0.1	1.1	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.1	1.7	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	2.8	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	1.3	GO:0001533	cornified envelope(GO:0001533)
0.1	0.4	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	8.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.9	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	55.4	GO:0005615	extracellular space(GO:0005615)
0.0	1.3	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0	3.3	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.6	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.3	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.8	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.0	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.7	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	4.0	GO:0005840	ribosome(GO:0005840)
0.0	3.5	GO:0000776	kinetochore(GO:0000776)
0.0	7.7	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.9	GO:0032809	neuronal cell body membrane(GO:0032809)
0.0	0.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	1.4	GO:0044291	cell-cell contact zone(GO:0044291)
0.0	0.7	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	1.2	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.4	GO:0000346	transcription export complex(GO:0000346)
0.0	0.9	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.8	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	2.4	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.8	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.5	GO:0032420	stereocilium(GO:0032420)
0.0	2.7	GO:0005759	mitochondrial matrix(GO:0005759)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	10.7	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
2.4	7.3	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
2.4	7.3	GO:0031826	follicle-stimulating hormone receptor binding(GO:0031762) type 2A serotonin receptor binding(GO:0031826)
2.0	6.1	GO:0005277	acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
2.0	6.1	GO:0035403	histone kinase activity (H3-T6 specific)(GO:0035403)
1.8	7.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.7	6.9	GO:0002061	uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061)
1.6	8.0	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
1.6	4.7	GO:0004566	beta-glucuronidase activity(GO:0004566)
1.6	14.2	GO:0043515	kinetochore binding(GO:0043515)
1.5	6.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
1.5	4.6	GO:0004528	phosphodiesterase I activity(GO:0004528)
1.5	5.9	GO:0003987	acetate-CoA ligase activity(GO:0003987)
1.5	5.8	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
1.4	4.3	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
1.4	7.0	GO:0043682	copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
1.3	4.0	GO:0003990	acetylcholinesterase activity(GO:0003990)
1.3	2.6	GO:0015116	sulfate transmembrane transporter activity(GO:0015116)
1.3	5.1	GO:0042806	fucose binding(GO:0042806)
1.2	3.7	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
1.2	3.7	GO:0031531	thyrotropin-releasing hormone receptor binding(GO:0031531)
1.2	6.0	GO:0032564	dATP binding(GO:0032564)
1.1	9.6	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
1.0	5.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
1.0	10.0	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
1.0	3.0	GO:0046980	peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
1.0	9.8	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
1.0	2.9	GO:0070698	type I activin receptor binding(GO:0070698)
1.0	9.7	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.9	10.8	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.9	4.5	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.9	2.6	GO:0004918	interleukin-8 receptor activity(GO:0004918)
0.8	21.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.8	2.3	GO:0016748	succinyltransferase activity(GO:0016748)
0.8	3.8	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.7	8.7	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.7	4.3	GO:0035473	lipase binding(GO:0035473)
0.7	4.3	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.7	7.5	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.7	9.5	GO:0051378	serotonin binding(GO:0051378)
0.7	1.3	GO:0038100	nodal binding(GO:0038100)
0.7	3.4	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.7	13.4	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.7	7.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.7	2.6	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.6	5.7	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.6	3.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.6	14.9	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.6	3.7	GO:0034235	GPI anchor binding(GO:0034235)
0.6	2.4	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.6	1.8	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.6	7.2	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.6	6.0	GO:0019957	C-C chemokine binding(GO:0019957)
0.6	8.8	GO:0005344	oxygen transporter activity(GO:0005344)
0.6	4.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.6	1.8	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.6	4.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.6	3.4	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.6	4.0	GO:0031433	telethonin binding(GO:0031433)
0.6	5.6	GO:0008131	primary amine oxidase activity(GO:0008131)
0.6	1.7	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.5	11.5	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.5	4.9	GO:0016778	diphosphotransferase activity(GO:0016778)
0.5	3.0	GO:0004954	prostanoid receptor activity(GO:0004954)
0.5	1.5	GO:0004825	methionine-tRNA ligase activity(GO:0004825)
0.5	2.0	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.5	3.8	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.5	5.1	GO:0008242	omega peptidase activity(GO:0008242)
0.5	14.5	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
0.5	1.4	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.5	9.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.5	3.6	GO:0070087	chromo shadow domain binding(GO:0070087)
0.4	9.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.4	6.5	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4	6.0	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.4	4.9	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4	4.0	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.4	1.2	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.4	7.0	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.4	1.5	GO:0004594	pantothenate kinase activity(GO:0004594)
0.4	1.5	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.4	4.6	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.4	4.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.4	3.4	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.4	1.9	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4	1.9	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.4	2.6	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.4	4.8	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.4	2.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.4	4.3	GO:1990405	protein antigen binding(GO:1990405)
0.4	1.8	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.3	3.5	GO:0019841	retinol binding(GO:0019841)
0.3	17.2	GO:0005044	scavenger receptor activity(GO:0005044)
0.3	13.5	GO:0001784	phosphotyrosine binding(GO:0001784)
0.3	2.0	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.3	3.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.3	11.4	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.3	5.5	GO:0001848	complement binding(GO:0001848)
0.3	1.9	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3	2.5	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.3	63.1	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.3	0.9	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.3	1.7	GO:1990715	mRNA CDS binding(GO:1990715)
0.3	2.8	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3	1.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.3	31.4	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.3	11.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.3	0.8	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.3	5.1	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.3	1.0	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2	3.2	GO:0008061	chitin binding(GO:0008061)
0.2	12.9	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.2	4.2	GO:0017081	chloride channel regulator activity(GO:0017081)
0.2	1.5	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.2	2.4	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2	6.1	GO:0004707	MAP kinase activity(GO:0004707)
0.2	3.7	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.2	7.0	GO:0015020	glucuronosyltransferase activity(GO:0015020)
0.2	3.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.2	0.9	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.2	13.7	GO:0016279	lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2	4.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.2	0.8	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2	3.9	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.2	2.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.2	1.3	GO:0030957	Tat protein binding(GO:0030957)
0.2	8.9	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2	1.8	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.2	4.1	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2	5.5	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.2	0.8	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	14.3	GO:0031490	chromatin DNA binding(GO:0031490)
0.1	3.3	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.7	GO:0090555	phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.1	1.0	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.1	0.4	GO:2001070	starch binding(GO:2001070)
0.1	2.8	GO:0017127	cholesterol transporter activity(GO:0017127)
0.1	1.9	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1	1.6	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.1	3.0	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1	6.6	GO:0003823	antigen binding(GO:0003823)
0.1	1.0	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.1	2.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	1.3	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	2.4	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.1	6.9	GO:0019843	rRNA binding(GO:0019843)
0.1	0.4	GO:0086077	gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1	0.1	GO:0016015	morphogen activity(GO:0016015)
0.1	0.7	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832)
0.1	2.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.6	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.7	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	3.0	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.1	0.9	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1	4.9	GO:0097110	scaffold protein binding(GO:0097110)
0.1	1.6	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.1	1.0	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.1	1.8	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	4.2	GO:0000049	tRNA binding(GO:0000049)
0.1	5.2	GO:0003724	RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1	3.0	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	4.6	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.1	0.8	GO:0019808	polyamine binding(GO:0019808)
0.1	2.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	5.1	GO:0017022	myosin binding(GO:0017022)
0.1	6.9	GO:0004540	ribonuclease activity(GO:0004540)
0.1	0.9	GO:0015250	water channel activity(GO:0015250)
0.1	1.4	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.1	5.2	GO:0051117	ATPase binding(GO:0051117)
0.1	9.4	GO:0001047	core promoter binding(GO:0001047)
0.1	1.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.1	1.0	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	0.9	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.1	1.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	2.7	GO:0031593	polyubiquitin binding(GO:0031593)
0.1	0.8	GO:0045125	bioactive lipid receptor activity(GO:0045125)
0.1	0.5	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.1	0.6	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	0.8	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.1	5.0	GO:0019955	cytokine binding(GO:0019955)
0.1	1.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.8	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.5	GO:0005521	lamin binding(GO:0005521)
0.0	1.3	GO:0004527	exonuclease activity(GO:0004527)
0.0	0.8	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.3	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.4	GO:0001671	ATPase activator activity(GO:0001671)
0.0	5.1	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.2	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	5.8	GO:0052689	carboxylic ester hydrolase activity(GO:0052689)
0.0	0.4	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.9	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.7	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	4.4	GO:0051015	actin filament binding(GO:0051015)
0.0	0.4	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.6	GO:0019239	deaminase activity(GO:0019239)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.4	GO:1900750	oligopeptide binding(GO:1900750)
0.0	1.2	GO:0046332	SMAD binding(GO:0046332)
0.0	4.1	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	1.4	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.0	1.7	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	1.6	GO:0070851	growth factor receptor binding(GO:0070851)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.2	GO:0043531	ADP binding(GO:0043531)
0.0	1.1	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
0.0	0.5	GO:0003725	double-stranded RNA binding(GO:0003725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	28.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.8	10.7	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.6	10.6	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.6	20.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.6	6.9	ST STAT3 PATHWAY	STAT3 Pathway
0.6	8.4	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.5	22.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4	32.7	PID IL4 2PATHWAY	IL4-mediated signaling events
0.4	8.6	PID CD40 PATHWAY	CD40/CD40L signaling
0.4	5.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.3	6.9	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3	12.9	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.2	4.8	PID IL23 PATHWAY	IL23-mediated signaling events
0.2	12.9	SIG CHEMOTAXIS	Genes related to chemotaxis
0.2	0.8	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2	15.5	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	3.3	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	2.6	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	5.9	PID AURORA B PATHWAY	Aurora B signaling
0.1	3.0	ST GA13 PATHWAY	G alpha 13 Pathway
0.1	4.8	PID PLK1 PATHWAY	PLK1 signaling events
0.1	4.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	2.0	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	1.6	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	2.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	2.0	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	4.2	PID P73PATHWAY	p73 transcription factor network
0.1	4.1	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	4.2	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	3.4	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	3.0	PID E2F PATHWAY	E2F transcription factor network
0.1	2.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	1.6	PID ALK1 PATHWAY	ALK1 signaling events
0.1	1.9	PID ENDOTHELIN PATHWAY	Endothelins
0.1	0.6	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	1.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	1.8	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	2.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	1.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.7	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.6	PID NOTCH PATHWAY	Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.5	19.8	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
1.2	18.6	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.9	7.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.7	9.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.7	6.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.6	4.8	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.5	6.0	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.5	7.0	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.5	6.9	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.5	10.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.5	8.4	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.5	6.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.5	26.9	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.5	7.7	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.5	5.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4	7.5	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.4	4.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.4	11.8	REACTOME KINESINS	Genes involved in Kinesins
0.4	4.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.4	3.4	REACTOME LAGGING STRAND SYNTHESIS	Genes involved in Lagging Strand Synthesis
0.4	5.5	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.4	7.0	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.3	9.9	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.3	3.0	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.3	8.6	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.3	7.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.3	7.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.3	5.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.3	29.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.3	3.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	6.1	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.3	2.0	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.2	11.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.2	4.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	10.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.2	4.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	7.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.2	7.0	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2	6.8	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.2	2.6	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.2	3.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.2	6.1	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.2	8.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.2	9.1	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.2	3.6	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.2	3.8	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.1	2.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	0.9	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	8.9	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.1	8.3	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.1	2.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	1.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	3.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	3.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	2.8	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1	1.1	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	2.0	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.1	1.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	0.8	REACTOME DNA STRAND ELONGATION	Genes involved in DNA strand elongation
0.1	0.7	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.1	0.9	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	1.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	4.3	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	1.9	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	1.0	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	1.8	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.1	1.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	3.6	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.1	3.1	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	4.7	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	1.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	0.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	4.2	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	0.8	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.1	0.6	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.1	2.3	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.8	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	1.1	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	1.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis

Results for Zic2

Z-value: 0.95

Motif logo

Transcription factors associated with Zic2

Activity-expression correlation:

Activity profile of Zic2 motif

Sorted Z-values of Zic2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zic2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: