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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfp784

Z-value: 1.01

Motif logo

Transcription factors associated with Zfp784

Gene Symbol Gene ID Gene Info

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp865rn6_v1_chr1_+_72356880_723568800.521.4e-23Click!

Activity profile of Zfp784 motif

Sorted Z-values of Zfp784 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_64554953 25.99 ENSRNOT00000067452
serine/arginine repetitive matrix protein 1-like
chr5_+_49311030 23.28 ENSRNOT00000010850
cannabinoid receptor 1
chr20_-_31956649 21.67 ENSRNOT00000072429
hexokinase 1
chr15_+_15275541 20.50 ENSRNOT00000012153
calcium dependent secretion activator
chr3_-_153893847 18.23 ENSRNOT00000085938
band 4.1-like protein 1-like
chr7_+_142912316 17.94 ENSRNOT00000010171
nuclear receptor subfamily 4, group A, member 1
chr7_-_113937941 17.68 ENSRNOT00000012408
potassium two pore domain channel subfamily K member 9
chr16_-_20097287 17.05 ENSRNOT00000025162
unc-13 homolog A
chr13_-_1946508 16.93 ENSRNOT00000043890
dermatan sulfate epimerase-like
chr2_-_200625434 16.73 ENSRNOT00000079754
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
chr7_+_117723263 16.66 ENSRNOT00000085152
kinesin family member C2
chr1_-_48825364 16.60 ENSRNOT00000024213
1-acylglycerol-3-phosphate O-acyltransferase 4
chr8_-_49038169 16.41 ENSRNOT00000047303
pleckstrin homology-like domain, family B, member 1
chr3_+_38559914 16.36 ENSRNOT00000085545
formin-like 2
chr14_-_43072843 16.31 ENSRNOT00000064263
LIM and calponin homology domains 1
chr7_-_139223116 16.07 ENSRNOT00000086559
endonuclease, poly(U)-specific
chr8_-_116361343 15.97 ENSRNOT00000066296
semaphorin 3B
chr1_+_168964202 15.66 ENSRNOT00000089102
hemoglobin subunit beta-2-like
chr3_+_152552822 15.61 ENSRNOT00000089719
erythrocyte membrane protein band 4.1-like 1
chr15_-_52317219 15.61 ENSRNOT00000016555
dematin actin binding protein
chr1_-_168972725 15.25 ENSRNOT00000090422
hemoglobin subunit beta
chr3_+_14467330 15.21 ENSRNOT00000078939
gelsolin
chr2_-_210454737 15.11 ENSRNOT00000079993
adenosylhomocysteinase-like 1
chr2_-_200692335 14.93 ENSRNOT00000026290
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
chr1_+_29225707 14.83 ENSRNOT00000018849
nuclear receptor coactivator 7
chr3_-_164055561 14.60 ENSRNOT00000064849
beta-1,4-galactosyltransferase 5
chr4_-_56114254 14.38 ENSRNOT00000010673
leucine rich repeat containing 4
chr10_+_107455845 14.27 ENSRNOT00000004373
C1q and tumor necrosis factor related protein 1
chr6_-_42616548 14.12 ENSRNOT00000081433
ATPase H+ transporting V1 subunit C2
chr11_-_11585078 14.08 ENSRNOT00000088878
roundabout guidance receptor 2
chr8_+_118333706 14.03 ENSRNOT00000028278
chondroitin sulfate proteoglycan 5
chr6_-_27190126 13.96 ENSRNOT00000068412
ENSRNOT00000013107
potassium two pore domain channel subfamily K member 3
chr12_+_25036605 13.88 ENSRNOT00000001996
ENSRNOT00000084427
LIM domain kinase 1
chr1_+_168945449 13.60 ENSRNOT00000087661
ENSRNOT00000019913
hemoglobin subunit beta-2-like
chr19_+_53723822 13.51 ENSRNOT00000023478
similar to RIKEN cDNA 6430548M08
chr1_-_81881549 12.95 ENSRNOT00000027497
ATPase Na+/K+ transporting subunit alpha 3
chr11_+_84396033 12.80 ENSRNOT00000002316
ATP binding cassette subfamily C member 5
chr2_+_199199845 12.74 ENSRNOT00000020932
tubulin alpha-1C chain-like
chr11_-_24641820 12.58 ENSRNOT00000044081
ENSRNOT00000048854
amyloid beta precursor protein
chr10_-_89130339 12.46 ENSRNOT00000027640
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr17_+_11101306 12.36 ENSRNOT00000030893
dopamine receptor D1
chr8_-_130127392 12.12 ENSRNOT00000026159
cholecystokinin
chr10_+_23661343 12.06 ENSRNOT00000047970
early B-cell factor 1
chr8_-_128754514 12.04 ENSRNOT00000025019
C-X3-C motif chemokine receptor 1
chr12_-_39850567 11.76 ENSRNOT00000001712
hydrogen voltage-gated channel 1
chr3_+_172374957 11.33 ENSRNOT00000035916
GNAS complex locus
chr5_+_74727494 11.32 ENSRNOT00000076683

chrX_-_156379189 11.26 ENSRNOT00000083148
plexin A3
chr19_+_25043680 11.25 ENSRNOT00000043971
adhesion G protein-coupled receptor L1
chr3_-_29996865 11.22 ENSRNOT00000080382
zinc finger E-box binding homeobox 2
chr7_+_11582984 11.16 ENSRNOT00000026893
G protein subunit gamma 7
chr13_-_49313940 10.59 ENSRNOT00000012190
contactin 2
chr19_+_54553419 10.10 ENSRNOT00000025392
junctophilin 3
chr9_-_19372673 10.00 ENSRNOT00000073667
ENSRNOT00000079517
chloride intracellular channel 5
chr1_+_171793782 9.81 ENSRNOT00000081351
olfactomedin-like 1
chr16_+_74810938 9.77 ENSRNOT00000058091
NIMA-related kinase 5
chr7_-_140617721 9.47 ENSRNOT00000081355
tubulin, alpha 1B
chr10_-_56831243 9.34 ENSRNOT00000025403
solute carrier family 16, member 13
chr2_-_231409988 9.33 ENSRNOT00000080637
ENSRNOT00000037255
ENSRNOT00000074002
ankyrin 2
chr3_+_145032200 9.32 ENSRNOT00000068210
synapse differentiation inducing 1
chr4_-_157252104 9.21 ENSRNOT00000082739
protein tyrosine phosphatase, non-receptor type 6
chrX_-_43592200 9.17 ENSRNOT00000005033
acyl-CoA thioesterase 9
chrX_-_71168612 9.17 ENSRNOT00000075934
interleukin 2 receptor subunit gamma
chr3_+_110442637 9.03 ENSRNOT00000010471
p21 (RAC1) activated kinase 6
chr8_+_111600532 9.03 ENSRNOT00000081952
RAB6B, member RAS oncogene family
chr10_+_84167331 9.02 ENSRNOT00000010965
homeo box B4
chr1_+_219403970 8.70 ENSRNOT00000029607
protein tyrosine phosphatase, receptor type, C-associated protein
chr20_-_4132604 8.52 ENSRNOT00000077630
ENSRNOT00000048332
RT1 class II, locus Da
chrX_+_78196300 8.43 ENSRNOT00000048695
purinergic receptor P2Y10
chr10_-_64657089 8.38 ENSRNOT00000080703
active BCR-related
chr6_+_9483594 8.34 ENSRNOT00000089272

chr12_+_52359310 8.05 ENSRNOT00000071857
ENSRNOT00000065893
fibrosin-like 1
chr5_-_148392689 7.70 ENSRNOT00000018464
ENSRNOT00000080166
tubulointerstitial nephritis antigen-like 1
chr5_+_118574801 7.65 ENSRNOT00000035949
ubiquitin-conjugating enzyme E2U (putative)
chr4_+_56805132 7.47 ENSRNOT00000010001
ENSRNOT00000085483
interferon regulatory factor 5
chr9_+_43889473 7.33 ENSRNOT00000024330
inositol polyphosphate-4-phosphatase type I A
chr6_-_39363367 7.14 ENSRNOT00000088687
ENSRNOT00000065531
family with sequence similarity 84, member A
chr8_+_132241134 6.89 ENSRNOT00000006055
C-type lectin domain family 3, member B
chrX_-_31851715 6.78 ENSRNOT00000068601
vascular endothelial growth factor D
chr14_-_45165207 6.74 ENSRNOT00000002960
Kruppel like factor 3
chr8_-_21968415 6.71 ENSRNOT00000067325
ENSRNOT00000064932
DNA methyltransferase 1
chr2_-_231648122 6.67 ENSRNOT00000014962
ankyrin 2
chr5_+_155660553 6.66 ENSRNOT00000081893
wingless-type MMTV integration site family, member 4
chr13_-_26768708 6.59 ENSRNOT00000092763
BCL2, apoptosis regulator
chr1_+_222672501 6.58 ENSRNOT00000051855
similar to RIKEN cDNA 2700081O15
chr10_+_23661013 6.37 ENSRNOT00000076664
early B-cell factor 1
chr2_+_72006099 6.22 ENSRNOT00000034044
cadherin 12
chr10_+_84182118 5.87 ENSRNOT00000011027
homeo box B3
chr4_+_88328061 5.77 ENSRNOT00000084775
vomeronasal 1 receptor 87
chr9_+_116652530 5.73 ENSRNOT00000029210
l(3)mbt-like 4 (Drosophila)
chr2_-_241545250 5.70 ENSRNOT00000073875
B-cell scaffold protein with ankyrin repeats 1
chr5_+_145079803 5.52 ENSRNOT00000084202
splicing factor proline and glutamine rich
chr1_+_69615603 5.51 ENSRNOT00000084806
zinc finger protein 418
chr1_+_276659542 5.46 ENSRNOT00000019681
transcription factor 7 like 2
chr20_+_46168177 5.39 ENSRNOT00000057175
zinc finger and BTB domain containing 24
chr7_-_144837583 5.35 ENSRNOT00000055289
chromobox 5
chr2_+_257568613 5.33 ENSRNOT00000066125
ubiquitin specific peptidase 33
chr4_+_7377563 5.24 ENSRNOT00000084826
potassium voltage-gated channel subfamily H member 2
chr4_+_155709613 5.24 ENSRNOT00000013272
NECAP endocytosis associated 1
chr18_-_37096132 5.19 ENSRNOT00000041188
protein phosphatase 2, regulatory subunit B, beta
chr1_+_69615434 4.96 ENSRNOT00000020751
zinc finger protein 418
chr12_+_32103198 4.90 ENSRNOT00000085464
transmembrane protein 132D
chr3_+_56861396 4.84 ENSRNOT00000000008
ENSRNOT00000084375
glutamate decarboxylase 1
chr4_-_119889949 4.83 ENSRNOT00000033687
H1 histone family, member X
chr1_-_82166363 4.80 ENSRNOT00000027774
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3
chr1_-_259674425 4.73 ENSRNOT00000091116
delta-1-pyrroline-5-carboxylate synthase
chr1_-_259089632 4.67 ENSRNOT00000020940
ENSRNOT00000091297
aldehyde dehydrogenase 18 family, member A1
chr3_+_148541909 4.64 ENSRNOT00000012187
CCM2 like scaffolding protein
chr14_-_84189266 4.57 ENSRNOT00000005934
transcobalamin 2
chr5_+_147714163 4.57 ENSRNOT00000012663
MARCKS-like 1
chr15_-_24199341 4.57 ENSRNOT00000015553
DLG associated protein 5
chr2_-_46042636 4.54 ENSRNOT00000087161

chr7_-_140502441 4.31 ENSRNOT00000089544
lysine methyltransferase 2D
chr17_+_81455955 4.28 ENSRNOT00000044313
solute carrier family 39 member 12
chr1_-_88826302 4.26 ENSRNOT00000028275
leucine rich repeat and fibronectin type III domain containing 3
chrX_+_123404518 4.17 ENSRNOT00000015085
solute carrier family 25 member 5
chr7_-_124367630 4.12 ENSRNOT00000055978
tubulin tyrosine ligase like 1
chr8_-_49308806 4.08 ENSRNOT00000047291
CD3e molecule
chr1_+_84685931 4.02 ENSRNOT00000063839
zinc finger protein 780B
chr1_+_280383579 3.99 ENSRNOT00000064022
ENSRNOT00000042977
potassium two pore domain channel subfamily K member 18
chr9_+_100489852 3.91 ENSRNOT00000022854
protein phosphatase 1, regulatory subunit 7
chr9_-_71852113 3.89 ENSRNOT00000083263
ENSRNOT00000072983

chr6_-_91518996 3.81 ENSRNOT00000005835
DNA polymerase epsilon 2, accessory subunit
chr8_+_127144903 3.76 ENSRNOT00000013530
eomesodermin
chr1_+_225184939 3.68 ENSRNOT00000079456
AHNAK nucleoprotein
chr11_-_14304603 3.67 ENSRNOT00000040202
ENSRNOT00000082143
SAM domain, SH3 domain and nuclear localization signals, 1
chr17_-_77527894 3.66 ENSRNOT00000032173
BEN domain containing 7
chr3_-_9822182 3.55 ENSRNOT00000076637
ENSRNOT00000010115
similar to Hypothetical protein MGC11690
chr1_-_16203838 3.53 ENSRNOT00000018556
ENSRNOT00000078586
phosphodiesterase 7B
chr9_-_20195566 3.52 ENSRNOT00000015223
adhesion G protein-coupled receptor F5
chr12_+_22153983 3.42 ENSRNOT00000080775
ENSRNOT00000001894
procollagen C-endopeptidase enhancer
chr3_-_10226286 3.40 ENSRNOT00000093627
far upstream element binding protein 3
chr2_-_211001258 3.39 ENSRNOT00000037336
ataxin 7-like 2
chr7_-_124286478 3.39 ENSRNOT00000088125
protein kinase C and casein kinase substrate in neurons 2
chr5_-_58198782 3.32 ENSRNOT00000023951
C-C motif chemokine ligand 21
chr1_+_1784078 3.31 ENSRNOT00000020098
large tumor suppressor kinase 1
chr2_-_184263564 3.28 ENSRNOT00000015279
F-box and WD repeat domain containing 7
chr17_-_56909992 3.23 ENSRNOT00000021801
BMP and activin membrane-bound inhibitor
chr3_+_91191837 3.18 ENSRNOT00000006097
recombination activating 2
chr7_+_122979021 3.18 ENSRNOT00000085707
zinc finger CCCH-type containing 7B
chr7_+_145068286 3.14 ENSRNOT00000088956
ENSRNOT00000065753
NCK associated protein 1 like
chr4_+_88832178 3.11 ENSRNOT00000088983
ATP-binding cassette, subfamily G (WHITE), member 2
chr2_-_205212681 3.05 ENSRNOT00000022575
thyroid stimulating hormone, beta
chrX_-_13116743 3.00 ENSRNOT00000004305
MID1 interacting protein 1
chr5_-_164844586 2.99 ENSRNOT00000011287
chloride voltage-gated channel 6
chrX_+_48196916 2.94 ENSRNOT00000045976
uncharacterized LOC302729
chr3_-_170378210 2.91 ENSRNOT00000055102
aurora kinase A
chr9_-_100306829 2.87 ENSRNOT00000038563
similar to hypothetical protein FLJ22671
chr18_+_72550219 2.85 ENSRNOT00000046847
SMAD family member 2
chr4_+_157513414 2.82 ENSRNOT00000078769
PILR alpha associated neural protein
chr14_-_5006594 2.82 ENSRNOT00000076571
zinc finger protein 326
chr17_+_6684621 2.81 ENSRNOT00000089138
similar to CG9752-PA
chr10_-_62032400 2.80 ENSRNOT00000086378
ENSRNOT00000004161
diphthamide biosynthesis 1
chr14_+_106153575 2.76 ENSRNOT00000010264
VPS54 GARP complex subunit
chr10_+_103703404 2.73 ENSRNOT00000086469
RAB37, member RAS oncogene family
chr16_+_50111306 2.70 ENSRNOT00000019302
cytochrome P450, family 4, subfamily v, polypeptide 3
chr14_+_100373129 2.69 ENSRNOT00000029980
WD repeat domain 92
chr8_-_131899023 2.65 ENSRNOT00000034690
zinc finger protein 445
chr5_+_172488708 2.49 ENSRNOT00000019930
MORN repeat containing 1
chr1_-_72464492 2.43 ENSRNOT00000068550
N-acetyltransferase 14
chr10_-_13075864 2.39 ENSRNOT00000005220
progestin and adipoQ receptor family member 4
chr11_-_68197772 2.35 ENSRNOT00000003060
ENSRNOT00000081875
Hspb associated protein 1
chr6_-_86924146 2.22 ENSRNOT00000029411
MIS18 binding protein 1
chr5_+_107711077 2.22 ENSRNOT00000029486
methylthioadenosine phosphorylase
chr1_-_234670113 2.20 ENSRNOT00000017133
similar to hypothetical protein D030056L22
chr16_+_32449116 2.19 ENSRNOT00000050549
chloride voltage-gated channel 3
chr10_+_52334240 2.16 ENSRNOT00000005518
zinc finger protein 18
chr5_+_152325871 2.07 ENSRNOT00000044711
ferritin light chain 1
chr9_-_100306194 2.05 ENSRNOT00000087584
similar to hypothetical protein FLJ22671
chr6_+_50528823 2.00 ENSRNOT00000008321
laminin subunit beta 1
chr8_-_94922017 2.00 ENSRNOT00000083934
centrosomal protein 162
chr13_+_101790865 1.98 ENSRNOT00000087784
TATA-box binding protein associated factor, RNA polymerase I subunit A
chr11_-_66759402 1.77 ENSRNOT00000003326
hematopoietic cell specific Lyn substrate 1
chrX_+_105575759 1.76 ENSRNOT00000088760
armadillo repeat containing, X-linked 3
chr15_+_28413461 1.72 ENSRNOT00000060521
transmembrane protein 253
chr12_-_38274036 1.71 ENSRNOT00000063990
kinetochore associated 1
chr19_+_33928356 1.63 ENSRNOT00000058162
endothelin receptor type A
chr1_-_72339395 1.63 ENSRNOT00000021772
zinc finger protein 580
chr7_+_24939498 1.59 ENSRNOT00000010601
cytoskeleton-associated protein 4
chr17_+_84881414 1.55 ENSRNOT00000034157
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr13_-_50261438 1.45 ENSRNOT00000051824
LRRGT00144
chr6_-_129509720 1.35 ENSRNOT00000006131
autophagy related 2B
chr1_-_101449829 1.35 ENSRNOT00000028315
ferritin light chain 1-like
chr5_+_78483893 1.33 ENSRNOT00000059183
ENSRNOT00000059181
regulator of G-protein signaling 3
chr7_-_144837395 1.29 ENSRNOT00000089024
chromobox 5
chr1_+_80777014 1.27 ENSRNOT00000079758
predicted gene, 19345
chr10_+_104523996 1.27 ENSRNOT00000065339
ENSRNOT00000086747
integrin subunit beta 4
chr12_-_39881352 1.20 ENSRNOT00000083296
protein phosphatase 1 catalytic subunit gamma
chr12_+_15857805 1.20 ENSRNOT00000001667
IQ motif containing E
chr7_+_2458833 1.20 ENSRNOT00000085092
nascent polypeptide-associated complex alpha subunit
chr1_+_165237847 1.14 ENSRNOT00000022963
phosphoglucomutase 2-like 1
chr11_-_33003021 1.14 ENSRNOT00000084134
runt-related transcription factor 1
chr1_-_221917901 1.11 ENSRNOT00000092270
solute carrier family 22 member 12
chr6_-_99843245 1.02 ENSRNOT00000080270
glutathione peroxidase 2
chr1_+_47942800 0.99 ENSRNOT00000079312
Wilms tumor 1 associated protein
chr7_-_116063078 0.99 ENSRNOT00000076932
ENSRNOT00000035496
glycosylphosphatidylinositol anchored molecule like
chr1_-_257498844 0.95 ENSRNOT00000019056
NOC3-like DNA replication regulator
chr12_+_38274297 0.95 ENSRNOT00000087905
ENSRNOT00000057788
arginine and serine rich coiled-coil 2
chr6_+_80108655 0.89 ENSRNOT00000006137
gem (nuclear organelle) associated protein 2
chr16_+_81756971 0.88 ENSRNOT00000044085
PCI domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp784

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 23.3 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
5.4 37.6 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
5.1 15.2 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of establishment of T cell polarity(GO:1903903) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
4.0 16.0 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
3.9 15.6 GO:0070560 protein secretion by platelet(GO:0070560)
3.8 15.2 GO:0010999 regulation of eIF2 alpha phosphorylation by heme(GO:0010999)
3.8 11.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
3.7 11.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
3.6 21.7 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
3.6 14.3 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
3.5 10.6 GO:0060167 clustering of voltage-gated potassium channels(GO:0045163) regulation of adenosine receptor signaling pathway(GO:0060167)
3.4 16.9 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
3.3 26.7 GO:0016199 axon midline choice point recognition(GO:0016199)
3.3 6.7 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
3.1 12.4 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
3.0 12.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
3.0 17.9 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
2.8 8.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
2.3 9.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
2.2 6.6 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) negative regulation of retinal cell programmed cell death(GO:0046671) cellular response to fluoride(GO:1902618)
2.2 15.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
2.1 29.3 GO:0015671 oxygen transport(GO:0015671)
2.0 31.7 GO:0042448 progesterone metabolic process(GO:0042448)
2.0 5.9 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
1.8 16.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
1.8 25.7 GO:0071294 cellular response to zinc ion(GO:0071294)
1.8 5.5 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
1.7 5.2 GO:1902303 negative regulation of potassium ion export(GO:1902303)
1.7 6.7 GO:0090309 DNA methylation on cytosine within a CG sequence(GO:0010424) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.6 11.3 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
1.5 4.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
1.5 14.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
1.4 53.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
1.4 13.0 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
1.4 8.5 GO:0002399 MHC class II protein complex assembly(GO:0002399) peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.3 9.0 GO:0048539 bone marrow development(GO:0048539)
1.3 16.4 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
1.2 12.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
1.1 3.3 GO:0035759 mesangial cell-matrix adhesion(GO:0035759)
1.1 3.3 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
1.1 3.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
1.0 3.1 GO:0019389 glucuronoside metabolic process(GO:0019389) response to 2,3,7,8-tetrachlorodibenzodioxine(GO:1904612)
1.0 4.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.0 12.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
1.0 6.8 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
1.0 4.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
1.0 2.9 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte maturation(GO:1900195)
0.9 9.4 GO:0006561 proline biosynthetic process(GO:0006561)
0.9 9.3 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.9 3.7 GO:1900224 zygotic specification of dorsal/ventral axis(GO:0007352) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.9 5.5 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.9 9.2 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.9 4.6 GO:0015889 cobalamin transport(GO:0015889)
0.9 14.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.9 4.3 GO:0001555 oocyte growth(GO:0001555)
0.8 11.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.8 3.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.8 5.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.8 3.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.7 2.2 GO:0070638 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.7 2.9 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.7 10.0 GO:0060088 diet induced thermogenesis(GO:0002024) auditory receptor cell stereocilium organization(GO:0060088)
0.7 8.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.7 2.0 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.6 6.9 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.6 7.5 GO:0032494 response to peptidoglycan(GO:0032494)
0.6 1.8 GO:0042531 regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.6 13.9 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.6 2.8 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.5 2.2 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.5 1.0 GO:0009609 response to symbiotic bacterium(GO:0009609)
0.5 10.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.5 3.4 GO:0070836 caveola assembly(GO:0070836)
0.5 5.7 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.5 4.2 GO:0015866 ADP transport(GO:0015866)
0.5 7.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.4 14.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.4 4.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.4 3.5 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.4 4.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.4 1.1 GO:2000870 regulation of progesterone secretion(GO:2000870) positive regulation of progesterone secretion(GO:2000872)
0.4 3.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.4 5.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.3 1.6 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.3 2.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.3 4.0 GO:0071435 potassium ion export(GO:0071435)
0.3 0.9 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.3 3.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.3 3.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 9.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.2 9.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 15.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2 13.5 GO:0031103 axon regeneration(GO:0031103)
0.2 5.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536) protein K48-linked deubiquitination(GO:0071108)
0.2 3.0 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.2 7.7 GO:0016574 histone ubiquitination(GO:0016574)
0.2 1.3 GO:0061450 trophoblast cell migration(GO:0061450)
0.1 3.7 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.1 9.8 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.1 0.4 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 1.1 GO:0015747 urate transport(GO:0015747)
0.1 0.8 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 3.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.4 GO:0044804 nucleophagy(GO:0044804)
0.1 0.6 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 15.3 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 3.0 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 3.1 GO:0033189 response to vitamin A(GO:0033189)
0.1 2.8 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.1 2.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 14.9 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 2.6 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 4.8 GO:0006334 nucleosome assembly(GO:0006334)
0.0 6.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 2.8 GO:0006400 tRNA modification(GO:0006400)
0.0 11.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 1.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.6 GO:0032757 positive regulation of interleukin-8 production(GO:0032757)
0.0 0.7 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 5.4 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 7.7 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.9 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 3.4 GO:0010952 positive regulation of peptidase activity(GO:0010952)
0.0 10.8 GO:0007017 microtubule-based process(GO:0007017)
0.0 0.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 3.1 GO:0007613 memory(GO:0007613)
0.0 5.2 GO:0006897 endocytosis(GO:0006897)
0.0 2.0 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 4.3 GO:0007409 axonogenesis(GO:0007409)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
4.2 25.3 GO:0044326 dendritic spine neck(GO:0044326)
4.2 12.6 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
4.0 44.5 GO:0005833 hemoglobin complex(GO:0005833)
2.8 14.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
2.5 15.2 GO:0030478 actin cap(GO:0030478)
2.1 17.1 GO:0044305 calyx of Held(GO:0044305) presynaptic active zone cytoplasmic component(GO:0098831)
1.9 7.7 GO:0033503 HULC complex(GO:0033503)
1.9 15.0 GO:0043203 axon hillock(GO:0043203)
1.8 5.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.7 13.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.3 20.5 GO:0031045 dense core granule(GO:0031045)
1.1 10.1 GO:0030314 junctional membrane complex(GO:0030314)
1.0 16.4 GO:0045180 basal cortex(GO:0045180)
1.0 6.9 GO:0001652 granular component(GO:0001652)
0.9 2.8 GO:0044609 DBIRD complex(GO:0044609)
0.9 3.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.8 5.5 GO:0042382 paraspeckles(GO:0042382)
0.8 3.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.7 4.2 GO:0071817 MMXD complex(GO:0071817)
0.7 2.8 GO:0000938 GARP complex(GO:0000938)
0.7 10.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.7 3.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.6 12.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.6 1.7 GO:1990423 RZZ complex(GO:1990423)
0.5 22.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 8.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.5 14.1 GO:0030673 axolemma(GO:0030673)
0.5 2.0 GO:0043259 laminin-1 complex(GO:0005606) laminin-2 complex(GO:0005607) laminin-10 complex(GO:0043259)
0.5 16.0 GO:0031430 M band(GO:0031430)
0.4 13.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.4 37.3 GO:0042734 presynaptic membrane(GO:0042734)
0.4 5.2 GO:0030125 clathrin vesicle coat(GO:0030125)
0.4 13.9 GO:0044295 axonal growth cone(GO:0044295)
0.4 2.0 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.4 3.1 GO:0031209 SCAR complex(GO:0031209)
0.4 4.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 11.5 GO:0097228 sperm principal piece(GO:0097228)
0.3 2.0 GO:0005879 axonemal microtubule(GO:0005879)
0.3 4.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.3 19.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.3 14.0 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.3 7.0 GO:0060077 inhibitory synapse(GO:0060077)
0.3 0.9 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 16.4 GO:0005871 kinesin complex(GO:0005871)
0.2 2.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.2 10.0 GO:0034707 chloride channel complex(GO:0034707)
0.2 5.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 14.3 GO:0005581 collagen trimer(GO:0005581)
0.2 9.3 GO:0031901 early endosome membrane(GO:0031901)
0.1 2.1 GO:0044754 autolysosome(GO:0044754)
0.1 38.6 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 0.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 3.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 20.4 GO:0008021 synaptic vesicle(GO:0008021)
0.1 1.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 5.3 GO:0005776 autophagosome(GO:0005776)
0.1 5.3 GO:0030315 T-tubule(GO:0030315)
0.1 5.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 36.9 GO:0031966 mitochondrial membrane(GO:0031966)
0.1 1.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 8.4 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.1 4.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.3 GO:0008305 integrin complex(GO:0008305)
0.0 5.0 GO:0001650 fibrillar center(GO:0001650)
0.0 9.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 5.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 5.4 GO:0016607 nuclear speck(GO:0016607)
0.0 1.3 GO:0000922 spindle pole(GO:0000922)
0.0 1.9 GO:0005874 microtubule(GO:0005874)
0.0 0.9 GO:0043679 axon terminus(GO:0043679)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.8 23.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
5.6 16.9 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
5.3 31.7 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
5.1 15.2 GO:0031720 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
4.1 12.4 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
3.8 15.2 GO:0045159 myosin II binding(GO:0045159)
3.8 15.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
3.6 21.7 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
3.1 12.6 GO:0051425 PTB domain binding(GO:0051425)
2.9 29.3 GO:0005344 oxygen transporter activity(GO:0005344)
2.8 14.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
2.4 7.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
2.4 12.0 GO:0019960 C-X3-C chemokine binding(GO:0019960)
2.4 11.8 GO:0015252 hydrogen ion channel activity(GO:0015252)
2.3 9.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
1.9 17.1 GO:0019992 diacylglycerol binding(GO:0019992)
1.9 11.3 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.8 12.5 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.6 14.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.6 9.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
1.5 9.2 GO:0019976 interleukin-2 binding(GO:0019976)
1.4 16.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
1.3 6.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.2 4.8 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
1.2 14.1 GO:0008046 axon guidance receptor activity(GO:0008046)
1.1 6.6 GO:0051434 BH3 domain binding(GO:0051434)
1.1 18.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
1.0 9.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
1.0 23.8 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
1.0 4.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.9 3.7 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.9 13.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.8 6.8 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.8 11.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.7 5.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.7 2.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.7 2.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.7 17.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.7 8.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.7 31.6 GO:0030507 spectrin binding(GO:0030507)
0.7 3.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.6 5.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.6 11.3 GO:0015643 toxic substance binding(GO:0015643)
0.6 4.6 GO:0031419 cobalamin binding(GO:0031419)
0.5 10.1 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.5 4.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.4 8.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.4 13.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.4 1.3 GO:0038132 neuregulin binding(GO:0038132)
0.4 11.2 GO:0070412 R-SMAD binding(GO:0070412)
0.4 9.0 GO:0031489 myosin V binding(GO:0031489)
0.3 3.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.3 1.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 23.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.3 3.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.3 3.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.3 4.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 23.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 11.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.2 2.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 17.7 GO:0005518 collagen binding(GO:0005518)
0.2 3.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 16.4 GO:0003777 microtubule motor activity(GO:0003777)
0.2 14.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 2.9 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 3.0 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 0.9 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 3.4 GO:0008199 ferric iron binding(GO:0008199)
0.2 16.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 10.6 GO:0043621 protein self-association(GO:0043621)
0.1 4.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 9.3 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 5.0 GO:0005109 frizzled binding(GO:0005109)
0.1 3.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 10.0 GO:0005254 chloride channel activity(GO:0005254)
0.1 2.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 3.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 10.7 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 3.3 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 13.9 GO:0031072 heat shock protein binding(GO:0031072)
0.1 7.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 1.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 5.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 1.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 3.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 3.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 7.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.2 GO:0005521 lamin binding(GO:0005521)
0.1 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 7.9 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 0.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 5.8 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 3.1 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 3.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 6.9 GO:0008201 heparin binding(GO:0008201)
0.0 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.4 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 1.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 2.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 6.9 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 2.7 GO:0004497 monooxygenase activity(GO:0004497)
0.0 4.8 GO:0045296 cadherin binding(GO:0045296)
0.0 2.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 2.7 GO:0003924 GTPase activity(GO:0003924)
0.0 0.8 GO:0030674 protein binding, bridging(GO:0030674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 22.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.8 38.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.5 17.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.4 26.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.4 9.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.4 17.9 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.3 24.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 53.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 15.6 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 9.2 PID EPO PATHWAY EPO signaling pathway
0.3 3.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 10.7 PID AURORA B PATHWAY Aurora B signaling
0.2 3.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 9.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.2 8.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 4.6 PID AURORA A PATHWAY Aurora A signaling
0.2 14.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 4.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 5.5 PID AP1 PATHWAY AP-1 transcription factor network
0.1 5.2 PID ATR PATHWAY ATR signaling pathway
0.1 3.3 PID MYC PATHWAY C-MYC pathway
0.1 6.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 3.2 PID BMP PATHWAY BMP receptor signaling
0.1 6.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 1.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 11.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.2 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 2.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.7 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 35.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
1.5 2.9 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.1 12.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
1.1 25.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.9 6.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.9 22.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.9 13.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.9 14.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.7 8.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.7 12.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.6 9.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.6 4.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.5 14.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.5 9.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 16.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.5 17.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.5 15.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.4 19.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.4 21.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.3 3.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 14.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.3 12.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 15.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.3 3.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 4.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 10.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 3.8 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.2 6.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.2 17.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 4.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 3.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 7.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 18.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 8.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 15.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 3.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 2.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 3.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 5.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 5.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 3.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 3.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 4.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation