ISMARA results: Zfp691

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfp691

Z-value: 1.33

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Transcription factors associated with Zfp691

Gene Symbol	Gene ID	Gene Info
Zfp691 NCBI RGD Ensembl	ENSRNOG00000007398	zinc finger protein 691

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Zfp691	rn6_v1_chr5_-_138222534_138222534	-0.34	4.2e-10	Click!

Activity profile of Zfp691 motif

Sorted Z-values of Zfp691 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr15_+_32811135 Show fit	61.37	ENSRNOT00000067689	AABR07017902.1 NCBI RGD Ensembl Show fit
chr11_-_37914983 Show fit	54.47	ENSRNOT00000039876	Mx1 NCBI RGD Ensembl Show fit	myxovirus (influenza virus) resistance 1
chr10_-_110232843 Show fit	46.72	ENSRNOT00000054934	Cd7 NCBI RGD Ensembl Show fit	Cd7 molecule
chr14_-_15258207 Show fit	46.23	ENSRNOT00000039383	Cxcl13 NCBI RGD Ensembl Show fit	C-X-C motif chemokine ligand 13
chr13_+_50164563 Show fit	45.85	ENSRNOT00000029533	Lax1 NCBI RGD Ensembl Show fit	lymphocyte transmembrane adaptor 1
chr6_-_138662365 Show fit	44.89	ENSRNOT00000066209 ENSRNOT00000084892	Ighm NCBI RGD Ensembl Show fit	immunoglobulin heavy constant mu
chr6_+_139486942 Show fit	42.66	ENSRNOT00000080320	AABR07065699.3 NCBI RGD Ensembl Show fit
chr6_-_138900915 Show fit	40.33	ENSRNOT00000075363	AABR07065656.3 NCBI RGD Ensembl Show fit
chr6_+_139486775 Show fit	39.95	ENSRNOT00000077771	AABR07065699.3 NCBI RGD Ensembl Show fit
chr10_-_31359699 Show fit	37.88	ENSRNOT00000081280	Cyfip2 NCBI RGD Ensembl Show fit	cytoplasmic FMR1 interacting protein 2

Showing 1 to 10 of 148 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp691

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
6.9	69.2	GO:0032831	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
6.1	54.5	GO:0003374	dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
1.1	46.7	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
11.6	46.2	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
1.7	45.9	GO:0000188	inactivation of MAPK activity(GO:0000188)
5.0	40.1	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
9.4	37.8	GO:0002913	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
4.5	36.0	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.5	32.6	GO:0006801	superoxide metabolic process(GO:0006801)
0.3	31.3	GO:0031532	actin cytoskeleton reorganization(GO:0031532)

Showing 1 to 10 of 69 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	91.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	62.9	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	60.0	GO:0005654	nucleoplasm(GO:0005654)
4.7	37.8	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.3	36.0	GO:0016363	nuclear matrix(GO:0016363)
0.1	34.6	GO:0098857	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	34.5	GO:0044421	extracellular region part(GO:0044421)
0.7	23.5	GO:0008305	integrin complex(GO:0008305)
0.1	23.0	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.7	19.5	GO:0042629	mast cell granule(GO:0042629)

Showing 1 to 10 of 49 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	86.3	GO:0003924	GTPase activity(GO:0003924)
11.5	69.2	GO:0019976	interleukin-2 binding(GO:0019976)
15.4	46.2	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
1.0	45.9	GO:0042169	SH2 domain binding(GO:0042169)
0.3	39.9	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.3	38.4	GO:0017124	SH3 domain binding(GO:0017124)
10.8	32.4	GO:0071791	chemokine (C-C motif) ligand 5 binding(GO:0071791)
0.1	28.3	GO:0005096	GTPase activator activity(GO:0005096)
2.4	24.0	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
3.9	23.5	GO:0070051	fibrinogen binding(GO:0070051)

Showing 1 to 10 of 55 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.3	69.5	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
2.0	69.2	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
1.1	65.2	PID IL12 2PATHWAY	IL12-mediated signaling events
0.7	46.7	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
1.3	46.2	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.7	31.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	30.5	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
1.6	24.0	PID S1P S1P4 PATHWAY	S1P4 pathway
1.0	23.5	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
2.0	22.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.

Showing 1 to 10 of 24 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.5	70.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
4.6	69.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.9	54.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
2.3	41.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
5.4	37.8	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
5.5	27.4	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	26.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
1.2	22.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.2	19.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	8.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing

Showing 1 to 10 of 22 entries

Results for Zfp691

Z-value: 1.33

Motif logo

Transcription factors associated with Zfp691

Activity-expression correlation:

Activity profile of Zfp691 motif

Sorted Z-values of Zfp691 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp691

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: