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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfp652

Z-value: 0.94

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Transcription factors associated with Zfp652

Gene Symbol Gene ID Gene Info
Zfp652
ENSRNOG00000017001 zinc finger protein 652

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp652rn6_v1_chr10_+_83556809_835568090.155.6e-03Click!

Activity profile of Zfp652 motif

Sorted Z-values of Zfp652 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_140483693 45.06 ENSRNOT00000089060
Ddn
dendrin
chrX_+_107496072 44.51 ENSRNOT00000003283
Plp1
proteolipid protein 1
chr8_+_55178289 43.55 ENSRNOT00000059127
Cryab
crystallin, alpha B
chr10_-_51778939 29.20 ENSRNOT00000078675
ENSRNOT00000057562
Myocd
myocardin
chr8_-_58542844 26.67 ENSRNOT00000012041
Elmod1
ELMO domain containing 1
chr6_+_119519714 25.52 ENSRNOT00000004955
Flrt2
fibronectin leucine rich transmembrane protein 2
chr5_-_152473868 25.29 ENSRNOT00000022130
Fam110d
family with sequence similarity 110, member D
chr6_-_42473738 24.52 ENSRNOT00000033327
Kcnf1
potassium voltage-gated channel modifier subfamily F member 1
chr18_-_61057365 22.86 ENSRNOT00000042352
Alpk2
alpha-kinase 2
chr2_+_187344056 22.48 ENSRNOT00000025314
Nes
nestin
chr15_-_28746042 22.46 ENSRNOT00000017730
Sall2
spalt-like transcription factor 2
chrX_-_134866210 21.44 ENSRNOT00000005331
Apln
apelin
chr1_-_72727112 21.39 ENSRNOT00000031172
Brsk1
BR serine/threonine kinase 1
chr4_+_114835064 21.04 ENSRNOT00000031964
LOC103692165
rhotekin
chr16_-_79973735 19.94 ENSRNOT00000057845
ENSRNOT00000086896
Dlgap2
DLG associated protein 2
chr3_-_66417741 19.35 ENSRNOT00000007662
Neurod1
neuronal differentiation 1
chr1_+_79989019 19.26 ENSRNOT00000020428
Dmpk
dystrophia myotonica-protein kinase
chr10_-_109224370 19.05 ENSRNOT00000005839
Aatk
apoptosis-associated tyrosine kinase
chr13_-_88436789 18.54 ENSRNOT00000003901
Ddr2
discoidin domain receptor tyrosine kinase 2
chr1_+_157920786 18.39 ENSRNOT00000014284
Fam181b
family with sequence similarity 181, member B
chr10_-_82852660 18.09 ENSRNOT00000005641
Pdk2
pyruvate dehydrogenase kinase 2
chr1_-_84254645 17.81 ENSRNOT00000077651
Sptbn4
spectrin, beta, non-erythrocytic 4
chr4_+_113968995 17.61 ENSRNOT00000079511
Rtkn
rhotekin
chr13_-_84331905 16.88 ENSRNOT00000004965
Dusp27
dual specificity phosphatase 27 (putative)
chr10_+_53466870 16.31 ENSRNOT00000057503
Pirt
phosphoinositide-interacting regulator of transient receptor potential channels
chr8_-_117237229 15.99 ENSRNOT00000071381
Klhdc8b
kelch domain containing 8B
chr17_-_15467320 15.82 ENSRNOT00000072490
ENSRNOT00000093561
Ogn
osteoglycin
chr18_+_61261418 15.73 ENSRNOT00000064250
Zfp532
zinc finger protein 532
chr9_-_113504605 15.57 ENSRNOT00000067974
Rab31
RAB31, member RAS oncogene family
chr10_+_31146107 15.39 ENSRNOT00000008184
Adam19
ADAM metallopeptidase domain 19
chr7_+_78558701 15.16 ENSRNOT00000006393
Rims2
regulating synaptic membrane exocytosis 2
chr13_+_60435946 15.05 ENSRNOT00000004342
B3galt2
Beta-1,3-galactosyltransferase 2
chr10_-_83332851 14.91 ENSRNOT00000007133
Nxph3
neurexophilin 3
chr2_+_50099576 14.79 ENSRNOT00000089218
Hcn1
hyperpolarization-activated cyclic nucleotide-gated potassium channel 1
chr4_+_140837745 14.66 ENSRNOT00000080663
Arl8b
ADP-ribosylation factor like GTPase 8B
chr17_-_14717420 14.39 ENSRNOT00000071131
LOC100910978
extracellular matrix protein 2-like
chr11_-_87017115 14.21 ENSRNOT00000051037
Rtn4r
reticulon 4 receptor
chr15_-_60766579 13.48 ENSRNOT00000079978
Akap11
A-kinase anchoring protein 11
chr1_+_150797084 12.96 ENSRNOT00000018990
Nox4
NADPH oxidase 4
chr4_+_7355574 12.68 ENSRNOT00000013800
Kcnh2
potassium voltage-gated channel subfamily H member 2
chr17_-_45154355 11.53 ENSRNOT00000084976
Zkscan4
zinc finger with KRAB and SCAN domains 4
chr10_+_56627411 11.33 ENSRNOT00000089108
ENSRNOT00000068493
Dlg4
discs large MAGUK scaffold protein 4
chr8_+_63600663 10.99 ENSRNOT00000012644
Hcn4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr4_-_84768249 10.94 ENSRNOT00000013205
Fkbp14
FK506 binding protein 14
chr17_-_15555919 10.61 ENSRNOT00000043852
Ecm2
extracellular matrix protein 2
chr6_-_51018050 10.59 ENSRNOT00000082691
Gpr22
G protein-coupled receptor 22
chr13_+_104284660 10.41 ENSRNOT00000005400
Dusp10
dual specificity phosphatase 10
chr3_+_45277348 10.24 ENSRNOT00000059246
Pkp4
plakophilin 4
chrX_+_82143789 9.98 ENSRNOT00000003724
Pou3f4
POU class 3 homeobox 4
chr11_+_74834050 9.57 ENSRNOT00000002333
Atp13a4
ATPase 13A4
chr3_-_162581610 9.27 ENSRNOT00000079324
Zmynd8
zinc finger, MYND-type containing 8
chr8_+_22189600 9.11 ENSRNOT00000061100
Pde4a
phosphodiesterase 4A
chr8_-_63350269 8.60 ENSRNOT00000042681
Cd276
Cd276 molecule
chr5_+_79055521 8.45 ENSRNOT00000010333
Col27a1
collagen type XXVII alpha 1 chain
chr1_+_199664173 7.46 ENSRNOT00000054980
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr10_+_18912865 7.28 ENSRNOT00000007393
Kcnmb1
potassium calcium-activated channel subfamily M regulatory beta subunit 1
chr10_-_86645529 6.75 ENSRNOT00000011947
Med24
mediator complex subunit 24
chr3_-_175601127 6.72 ENSRNOT00000081226
Lama5
laminin subunit alpha 5
chr11_+_57404196 6.67 ENSRNOT00000042754
ENSRNOT00000034097
Phldb2
pleckstrin homology-like domain, family B, member 2
chr1_-_248898607 6.16 ENSRNOT00000074393
NEWGENE_1307313
dickkopf WNT signaling pathway inhibitor 1
chr13_-_103080920 6.12 ENSRNOT00000034990
AABR07022022.1

chr13_+_71107465 5.45 ENSRNOT00000003239
Rgs8
regulator of G-protein signaling 8
chr10_-_81942188 5.43 ENSRNOT00000003784
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr12_-_31249118 5.42 ENSRNOT00000058586
ENSRNOT00000073105
Adgrd1
adhesion G protein-coupled receptor D1
chr1_-_239057732 4.41 ENSRNOT00000024775
Gda
guanine deaminase
chr9_+_93326283 4.01 ENSRNOT00000024578
B3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr6_-_102196138 3.81 ENSRNOT00000014132
Tmem229b
transmembrane protein 229B
chr6_+_99625306 3.67 ENSRNOT00000008573
Plekhg3
pleckstrin homology and RhoGEF domain containing G3
chr8_-_71052529 3.63 ENSRNOT00000033512
Ankdd1a
ankyrin repeat and death domain containing 1A
chr13_-_85443727 3.25 ENSRNOT00000090668
ENSRNOT00000076125
Uck2
uridine-cytidine kinase 2
chr7_-_123088819 2.78 ENSRNOT00000056077
AC096601.1

chr1_-_43638161 2.74 ENSRNOT00000024460
Ipcef1
interaction protein for cytohesin exchange factors 1
chr7_-_117259141 2.43 ENSRNOT00000040762
Plec
plectin
chr14_-_44845218 2.28 ENSRNOT00000004003
Klhl5
kelch-like family member 5
chr6_-_108596446 2.25 ENSRNOT00000031331
ENSRNOT00000077458
ENSRNOT00000082792
Ltbp2
latent transforming growth factor beta binding protein 2
chr12_+_22835019 2.18 ENSRNOT00000059530
Col26a1
collagen type XXVI alpha 1 chain
chr3_-_113423149 1.86 ENSRNOT00000021008
Serinc4
serine incorporator 4
chr2_-_189856090 1.77 ENSRNOT00000020307
Npr1
natriuretic peptide receptor 1
chr8_+_117648745 1.66 ENSRNOT00000027762
Slc26a6
solute carrier family 26 member 6
chr1_+_229461127 1.53 ENSRNOT00000035813
Olr332
olfactory receptor 332
chr1_-_84040433 0.86 ENSRNOT00000018696
Itpkc
inositol-trisphosphate 3-kinase C
chr6_+_76383446 0.39 ENSRNOT00000010188
Insm2
INSM transcriptional repressor 2
chr10_+_12929471 0.17 ENSRNOT00000036563
Zscan10
zinc finger and SCAN domain containing 10
chr4_+_157554794 0.03 ENSRNOT00000024116
Ing4
inhibitor of growth family, member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp652

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.7 29.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
5.6 22.5 GO:0045105 intermediate filament polymerization or depolymerization(GO:0045105)
5.4 43.6 GO:0007021 tubulin complex assembly(GO:0007021)
5.4 21.4 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
4.5 18.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
4.3 25.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
4.2 12.7 GO:1902303 negative regulation of potassium ion export(GO:1902303)
3.9 19.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
3.9 19.3 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
3.7 14.8 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
2.9 8.6 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
2.8 31.3 GO:0046710 GDP metabolic process(GO:0046710)
2.6 10.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
2.5 37.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
2.4 14.2 GO:0023041 neuronal signal transduction(GO:0023041)
2.3 9.3 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
2.2 11.0 GO:1904045 cellular response to aldosterone(GO:1904045)
2.1 8.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
2.0 17.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
1.9 18.5 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
1.8 7.3 GO:1903413 cellular response to bile acid(GO:1903413)
1.7 6.7 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
1.2 15.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
1.1 19.1 GO:0032482 Rab protein signal transduction(GO:0032482)
1.1 15.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
1.1 7.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
1.0 38.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.9 4.4 GO:0046098 guanine metabolic process(GO:0046098)
0.8 15.6 GO:0090382 phagosome maturation(GO:0090382)
0.7 13.0 GO:0050667 homocysteine metabolic process(GO:0050667)
0.7 22.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.7 10.0 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.6 1.7 GO:0046724 oxalic acid secretion(GO:0046724)
0.5 16.3 GO:0048266 behavioral response to pain(GO:0048266)
0.5 5.4 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.5 5.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.3 1.3 GO:0044211 CTP salvage(GO:0044211)
0.3 21.4 GO:0051298 centrosome duplication(GO:0051298)
0.3 15.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.3 17.6 GO:0048662 negative regulation of smooth muscle cell proliferation(GO:0048662)
0.2 10.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 6.7 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.2 10.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 14.7 GO:0032418 lysosome localization(GO:0032418)
0.2 1.9 GO:0015825 L-serine transport(GO:0015825)
0.1 14.1 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 2.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 6.8 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 19.6 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 2.3 GO:0097435 fibril organization(GO:0097435)
0.1 3.9 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 14.9 GO:0021915 neural tube development(GO:0021915)
0.1 6.2 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.1 6.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 16.9 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 11.6 GO:0016567 protein ubiquitination(GO:0016567)
0.0 2.9 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 2.4 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 25.8 GO:0098855 HCN channel complex(GO:0098855)
6.0 18.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
4.8 43.6 GO:0097512 cardiac myofibril(GO:0097512)
3.0 45.1 GO:0032591 dendritic spine membrane(GO:0032591)
2.2 17.8 GO:0043203 axon hillock(GO:0043203)
1.7 6.7 GO:0043259 laminin-10 complex(GO:0043259)
1.3 13.0 GO:0043020 NADPH oxidase complex(GO:0043020)
1.3 11.3 GO:0098839 postsynaptic density membrane(GO:0098839)
1.2 19.9 GO:0005883 neurofilament(GO:0005883)
1.0 22.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.8 14.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.7 24.9 GO:0051233 spindle midzone(GO:0051233)
0.7 8.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.7 19.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.6 15.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.5 6.7 GO:0045180 basal cortex(GO:0045180)
0.4 19.1 GO:0044295 axonal growth cone(GO:0044295)
0.4 44.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.4 15.2 GO:0060077 inhibitory synapse(GO:0060077)
0.2 18.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 4.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 5.4 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 2.4 GO:0030056 hemidesmosome(GO:0030056)
0.2 44.5 GO:0043209 myelin sheath(GO:0043209)
0.2 60.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 22.5 GO:0005882 intermediate filament(GO:0005882)
0.1 9.3 GO:0043198 dendritic shaft(GO:0043198)
0.1 21.4 GO:0008021 synaptic vesicle(GO:0008021)
0.1 1.7 GO:0097225 sperm midpiece(GO:0097225)
0.1 26.0 GO:0005925 focal adhesion(GO:0005925)
0.0 19.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 5.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 22.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 6.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 4.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 12.4 GO:0005794 Golgi apparatus(GO:0005794)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 25.0 GO:0070052 collagen V binding(GO:0070052)
4.8 38.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
4.5 18.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
3.7 44.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
3.1 31.3 GO:0004385 guanylate kinase activity(GO:0004385)
3.0 15.0 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
2.6 18.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
2.6 25.8 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
2.1 25.5 GO:0045499 chemorepellent activity(GO:0045499)
2.0 43.1 GO:0005212 structural constituent of eye lens(GO:0005212)
1.9 22.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
1.8 12.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
1.8 14.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.6 21.4 GO:0050321 tau-protein kinase activity(GO:0050321)
1.5 7.5 GO:0048495 Roundabout binding(GO:0048495)
1.4 13.0 GO:0016175 NAD(P)H oxidase activity(GO:0016174) superoxide-generating NADPH oxidase activity(GO:0016175)
1.0 29.2 GO:0070412 R-SMAD binding(GO:0070412)
1.0 10.0 GO:0003680 AT DNA binding(GO:0003680)
0.8 10.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.7 10.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6 13.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.6 1.8 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.6 14.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.6 1.7 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.5 21.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.5 20.2 GO:0030506 ankyrin binding(GO:0030506)
0.5 9.1 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.5 19.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.4 16.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.4 9.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.4 9.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 16.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 1.3 GO:0004849 uridine kinase activity(GO:0004849)
0.3 19.3 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.3 7.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 15.6 GO:0019003 GDP binding(GO:0019003)
0.2 19.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.2 6.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 4.4 GO:0019239 deaminase activity(GO:0019239)
0.2 1.9 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 5.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 8.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 4.0 GO:0008378 galactosyltransferase activity(GO:0008378)
0.1 19.1 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.1 15.2 GO:0044325 ion channel binding(GO:0044325)
0.1 15.4 GO:0017124 SH3 domain binding(GO:0017124)
0.1 26.7 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 3.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 22.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 5.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 15.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 6.7 GO:0045296 cadherin binding(GO:0045296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 15.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 11.3 ST GA12 PATHWAY G alpha 12 Pathway
0.3 21.4 PID LKB1 PATHWAY LKB1 signaling events
0.3 2.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 29.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 13.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 10.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 10.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 6.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 4.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 18.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.1 15.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.7 19.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.7 37.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.6 17.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.5 33.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.4 4.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 10.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 4.0 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 8.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 6.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 6.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 2.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events