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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfp524

Z-value: 1.19

Motif logo

Transcription factors associated with Zfp524

Gene Symbol Gene ID Gene Info
ENSRNOG00000016565 zinc finger protein 524

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp524rn6_v1_chr1_-_72377434_723774340.453.6e-17Click!

Activity profile of Zfp524 motif

Sorted Z-values of Zfp524 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_89386023 31.94 ENSRNOT00000086223
Fc fragment of IgG receptor IIIa
chr13_+_89385859 29.46 ENSRNOT00000047434
Fc fragment of IgG receptor IIIa
chr3_-_80012750 26.58 ENSRNOT00000018154
nuclear receptor subfamily 1, group H, member 3
chr19_+_24456976 26.49 ENSRNOT00000004900
uncoupling protein 1
chr4_+_99239115 25.55 ENSRNOT00000009515
CD8a molecule
chr1_-_73619356 24.78 ENSRNOT00000074352
leukocyte immunoglobulin like receptor B3
chr17_+_24416651 24.14 ENSRNOT00000024458
CD83 molecule
chr13_+_83996080 22.71 ENSRNOT00000004403
ENSRNOT00000070958
Cd247 molecule
chr13_-_50499060 21.83 ENSRNOT00000065347
ENSRNOT00000076924
ethanolamine kinase 2
chr9_-_9985358 20.51 ENSRNOT00000080856
crumbs 3, cell polarity complex component
chr20_+_3990820 20.20 ENSRNOT00000000528
proteasome subunit beta 8
chr8_-_62424303 19.54 ENSRNOT00000091223
c-src tyrosine kinase
chr10_-_70341837 19.14 ENSRNOT00000077261
schlafen family member 13
chr1_-_85317968 19.06 ENSRNOT00000026891
glia maturation factor, gamma
chr8_+_22035256 18.84 ENSRNOT00000028066
intercellular adhesion molecule 1
chr4_-_157252565 18.79 ENSRNOT00000079947
protein tyrosine phosphatase, non-receptor type 6
chr11_-_70499200 18.45 ENSRNOT00000002439
solute carrier family 12, member 8
chr5_+_137255924 18.09 ENSRNOT00000088022
ENSRNOT00000092755
ELOVL fatty acid elongase 1
chr3_-_14112851 17.84 ENSRNOT00000092736
complement C5
chr10_-_88442796 17.56 ENSRNOT00000077579
ENSRNOT00000023447
ENSRNOT00000043172
ATP citrate lyase
chr1_-_101095594 17.36 ENSRNOT00000027944
Fc fragment of IgG receptor and transporter
chr19_-_838099 16.61 ENSRNOT00000014234
CKLF-like MARVEL transmembrane domain containing 3
chr10_+_63803309 16.50 ENSRNOT00000036666
myosin 1C
chr4_-_163402561 16.31 ENSRNOT00000091890
killer cell lectin like receptor K1
chr2_-_23256158 16.30 ENSRNOT00000015336
betaine-homocysteine S-methyltransferase
chr13_-_47979797 16.07 ENSRNOT00000080035
Ras association domain family member 5
chr1_+_145770135 15.86 ENSRNOT00000015320
StAR-related lipid transfer domain containing 5
chr9_-_10471009 15.73 ENSRNOT00000072868
scaffold attachment factor B
chr14_-_82287706 15.51 ENSRNOT00000080695
fibroblast growth factor receptor 3
chr3_+_18706988 15.35 ENSRNOT00000074650

chr17_+_9639330 15.01 ENSRNOT00000018232
docking protein 3
chr11_+_87204175 14.74 ENSRNOT00000000306
solute carrier family 25 member 1
chr20_-_5212624 14.55 ENSRNOT00000074261
antigen peptide transporter 2
chr10_+_86340940 14.53 ENSRNOT00000073486
phenylethanolamine-N-methyltransferase
chr6_+_49968473 14.42 ENSRNOT00000007466
family with sequence similarity 110, member C
chr10_+_15241590 13.96 ENSRNOT00000037372
ENSRNOT00000037381
methyltransferase like 26
chr4_+_152995865 13.82 ENSRNOT00000014885
interleukin 17 receptor A
chr19_-_19376789 13.82 ENSRNOT00000065103
nucleotide-binding oligomerization domain containing 2
chr8_+_49282460 13.72 ENSRNOT00000021488
CD3d molecule
chr10_+_109707962 13.68 ENSRNOT00000054962
ENSRNOT00000088898
glucagon receptor
chr6_-_11298216 13.66 ENSRNOT00000021135
epithelial cell adhesion molecule
chr13_+_52976507 13.49 ENSRNOT00000090599
ENSRNOT00000011324
kinesin family member 21B
chr8_-_22336794 13.43 ENSRNOT00000066340
adaptor-related protein complex 1, mu 2 subunit
chr7_-_73270308 13.42 ENSRNOT00000007430
reactive intermediate imine deaminase A homolog
chr3_-_113405829 13.14 ENSRNOT00000036823
elongation factor for RNA polymerase II 3
chr8_+_67295727 12.93 ENSRNOT00000020443
acidic nuclear phosphoprotein 32 family member A
chr11_+_47243342 12.51 ENSRNOT00000041116
NFKB inhibitor zeta
chr10_-_55965216 12.46 ENSRNOT00000057058
chromodomain helicase DNA binding protein 3
chr7_-_3170146 12.38 ENSRNOT00000036373
diacylglycerol kinase, alpha
chr1_+_191829555 12.23 ENSRNOT00000067138
sodium channel epithelial 1 beta subunit
chr4_+_171748273 12.07 ENSRNOT00000009998
deoxyribose-phosphate aldolase
chr10_+_3218466 12.03 ENSRNOT00000093629
ENSRNOT00000093338
ENSRNOT00000077695
N-terminal asparagine amidase
chr20_+_3744395 11.88 ENSRNOT00000086065
transcription factor 19
chr2_-_47096961 11.76 ENSRNOT00000077401
integrin alpha 2
chr8_-_61919874 11.76 ENSRNOT00000064830
similar to human chromosome 15 open reading frame 39
chr8_-_128026841 11.72 ENSRNOT00000018341
myeloid differentiation primary response 88
chr7_+_97984862 11.58 ENSRNOT00000008508
ATPase family, AAA domain containing 2
chr3_-_55822551 11.57 ENSRNOT00000082624
LDL receptor related protein 2
chr3_+_66193059 11.56 ENSRNOT00000006880
integrin subunit alpha 4
chr3_-_10375826 11.51 ENSRNOT00000093365
argininosuccinate synthase 1
chr6_-_51356383 11.46 ENSRNOT00000012415
protein kinase cAMP-dependent type 2 regulatory subunit beta
chr19_+_54314865 11.46 ENSRNOT00000024069
interferon regulatory factor 8
chr11_+_47260641 11.45 ENSRNOT00000078856
NFKB inhibitor zeta
chr10_-_91448477 11.44 ENSRNOT00000038836
Rho GTPase activating protein 27
chr13_+_89774764 11.43 ENSRNOT00000005619
Rho GTPase activating protein 30
chr20_-_45259928 11.38 ENSRNOT00000087226
solute carrier family 16 member 10
chr4_-_119714302 11.36 ENSRNOT00000013299
RAB43, member RAS oncogene family
chr6_-_45669148 11.30 ENSRNOT00000010092
radical S-adenosyl methionine domain containing 2
chr8_+_11888591 11.17 ENSRNOT00000083967
coiled-coil domain containing 82
chr18_-_28425944 11.13 ENSRNOT00000084372
solute carrier family 23 member 1
chrX_+_123205869 11.00 ENSRNOT00000017101
ENSRNOT00000079231
progesterone receptor membrane component 1
chr7_+_2605719 11.00 ENSRNOT00000018737
glutaminase 2
chr1_-_88881460 11.00 ENSRNOT00000028287
hematopoietic cell signal transducer
chr4_-_69268336 10.98 ENSRNOT00000018042
protease, serine, 3B
chr1_+_217018916 10.88 ENSRNOT00000028195
ENSRNOT00000078979
7-dehydrocholesterol reductase
chr1_+_16910069 10.81 ENSRNOT00000020015
aldehyde dehydrogenase 8 family, member A1
chr9_+_20765296 10.71 ENSRNOT00000016291
CD2-associated protein
chr11_-_80981415 10.51 ENSRNOT00000002499
ENSRNOT00000002496
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr10_-_70744315 10.49 ENSRNOT00000014865
C-C motif chemokine ligand 5
chr5_+_154311998 10.45 ENSRNOT00000084085
UDP-galactose-4-epimerase
chr1_-_72941869 10.35 ENSRNOT00000032306
EPS8-like 1
chr4_+_109467272 10.35 ENSRNOT00000008212
regenerating family member 3 beta
chrX_-_104791210 10.33 ENSRNOT00000004921
synaptotagmin-like 4
chr7_+_41475163 10.25 ENSRNOT00000037844
dual specificity phosphatase 6
chr1_+_226687258 10.22 ENSRNOT00000079679
von Willebrand factor C and EGF domains
chr5_+_172648950 10.19 ENSRNOT00000055361
Fanconi anemia core complex associated protein 20
chr16_+_1749191 10.12 ENSRNOT00000014004
zinc finger, MIZ-type containing 1
chr5_-_152122542 10.10 ENSRNOT00000068634
ENSRNOT00000077248
ribosomal protein S6 kinase A1
chr15_+_40937708 10.09 ENSRNOT00000018407
spermatogenesis associated 13
chr14_-_33164141 10.04 ENSRNOT00000002844
RE1-silencing transcription factor
chr19_+_24800072 10.03 ENSRNOT00000005470
prostaglandin E receptor 1
chr15_+_28074953 10.03 ENSRNOT00000086427
ribonuclease pancreatic beta-type
chr13_+_49074644 10.01 ENSRNOT00000000041
kelch domain containing 8A
chr20_-_30749940 9.98 ENSRNOT00000065127
sphingosine-1-phosphate lyase 1
chr2_-_230273709 9.94 ENSRNOT00000012587
mitochondrial calcium uniporter dominant negative beta subunit
chr4_-_153465203 9.90 ENSRNOT00000016776
BH3 interacting domain death agonist
chr2_-_200513564 9.90 ENSRNOT00000056173
phosphoglycerate dehydrogenase
chr6_+_132762280 9.85 ENSRNOT00000004070
solute carrier family 25, member 47
chr7_-_107616038 9.83 ENSRNOT00000088752
src-like adaptor
chr20_+_3995544 9.83 ENSRNOT00000000527
transporter 2, ATP binding cassette subfamily B member
chr10_-_105116916 9.70 ENSRNOT00000012373
envoplakin
chr1_-_198486157 9.67 ENSRNOT00000022758
zymogen granule protein 16
chr19_-_15540773 9.60 ENSRNOT00000022359
lysophosphatidylcholine acyltransferase 2
chr16_+_19800463 9.49 ENSRNOT00000023065
ankyrin repeat and LEM domain containing 1
chr19_-_10513349 9.45 ENSRNOT00000061270
adhesion G protein-coupled receptor G5
chr12_-_16126953 9.42 ENSRNOT00000001682
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_78833157 9.35 ENSRNOT00000022461
prostaglandin I2 (prostacyclin) receptor (IP)
chr7_-_119768082 9.30 ENSRNOT00000009612
somatostatin receptor 3
chr10_+_75149814 9.28 ENSRNOT00000011500
Meckel syndrome, type 1
chr12_-_41448668 9.20 ENSRNOT00000001856
RAS protein activator like 1 (GAP1 like)
chr1_-_191007503 9.15 ENSRNOT00000023262
immunoglobulin superfamily, member 6
chr7_+_116355698 9.12 ENSRNOT00000076693
lymphocyte antigen 6 complex, locus E
chr10_+_76343847 9.10 ENSRNOT00000055674
tripartite motif-containing 25
chr10_+_4578469 9.07 ENSRNOT00000003332
thioredoxin domain containing 11
chr6_+_29012207 9.06 ENSRNOT00000079077
ATPase family, AAA domain containing 2B
chr11_+_73936750 8.97 ENSRNOT00000002350
ATPase 13A3
chr3_-_81282157 8.97 ENSRNOT00000051258
LARGE xylosyl- and glucuronyltransferase 2
chr10_-_70342411 8.95 ENSRNOT00000076269
ENSRNOT00000076477
schlafen family member 13
chr15_+_24141651 8.83 ENSRNOT00000082304
galectin 3
chr5_+_156215417 8.74 ENSRNOT00000067616
ENSRNOT00000077742
endothelin converting enzyme 1
chr10_-_72545141 8.72 ENSRNOT00000033684
amyloid beta precursor protein binding protein 2
chr3_+_161298962 8.61 ENSRNOT00000066028
cathepsin A
chr12_+_23473270 8.61 ENSRNOT00000001935
SH2B adaptor protein 2
chr7_+_116355911 8.47 ENSRNOT00000076182
lymphocyte antigen 6 complex, locus E
chr10_+_84182118 8.27 ENSRNOT00000011027
homeo box B3
chr5_-_139853247 8.24 ENSRNOT00000056644
exonuclease 5
chr1_+_137014272 8.22 ENSRNOT00000014802
A-kinase anchoring protein 13
chr10_-_94352880 8.21 ENSRNOT00000035973
LIM domain containing 2
chr12_-_41590244 8.19 ENSRNOT00000038736
solute carrier family 8 member B1
chr1_-_89474252 8.18 ENSRNOT00000028597
FXYD domain-containing ion transport regulator 5
chr5_-_24255606 8.15 ENSRNOT00000037483
pleckstrin homology and FYVE domain containing 2
chr1_-_89042176 8.10 ENSRNOT00000080842
lysine methyltransferase 2B
chr20_+_46199981 8.04 ENSRNOT00000000337
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr10_+_87774552 8.02 ENSRNOT00000044342
keratin associated protein 9-1
chr7_+_70612103 7.96 ENSRNOT00000057833
Rho GTPase activating protein 9
chr2_+_212247451 7.95 ENSRNOT00000027813
vav guanine nucleotide exchange factor 3
chr4_+_118207862 7.95 ENSRNOT00000085787
ENSRNOT00000023103
TIA1 cytotoxic granule-associated RNA binding protein
chr1_+_235166718 7.87 ENSRNOT00000020201
G protein subunit alpha 14
chr13_+_83073866 7.85 ENSRNOT00000075996
dermatopontin
chr16_-_20383337 7.79 ENSRNOT00000025977
interleukin 12 receptor subunit beta 1
chr12_-_46718355 7.76 ENSRNOT00000030031
RAB35, member RAS oncogene family
chr20_-_2212171 7.72 ENSRNOT00000085912
tripartite motif-containing 26
chr1_+_277355619 7.72 ENSRNOT00000022788
NHL repeat containing 2
chr7_+_11301957 7.63 ENSRNOT00000027847
tight junction protein 3
chr12_-_1512130 7.62 ENSRNOT00000086278

chr15_-_42517553 7.61 ENSRNOT00000081500
ENSRNOT00000021320
establishment of sister chromatid cohesion N-acetyltransferase 2
chr2_+_225005019 7.57 ENSRNOT00000015579
calponin 3
chr7_+_119820537 7.55 ENSRNOT00000077256
ENSRNOT00000056221
cytohesin 4
chr1_+_31967978 7.52 ENSRNOT00000081471
ENSRNOT00000021532
thyroid hormone receptor interactor 13
chr4_-_113886994 7.48 ENSRNOT00000037333
HtrA serine peptidase 2
chr16_+_20039969 7.44 ENSRNOT00000024866
collagen beta(1-O)galactosyltransferase 1
chr7_-_24004774 7.43 ENSRNOT00000007549
PWP1 homolog, endonuclein
chr1_-_221041401 7.40 ENSRNOT00000064136
pecanex homolog 3 (Drosophila)
chr1_-_80056574 7.35 ENSRNOT00000021200
glutaminyl-peptide cyclotransferase-like
chr8_+_49354115 7.34 ENSRNOT00000032837
myelin protein zero-like 3
chr19_+_41710102 7.33 ENSRNOT00000021866
ENSRNOT00000079730
MARVEL domain containing 3
chr7_+_2458264 7.26 ENSRNOT00000003550
nascent polypeptide-associated complex alpha subunit
chr1_+_157701089 7.23 ENSRNOT00000014271
prolylcarboxypeptidase
chr19_+_15094309 7.22 ENSRNOT00000083500
carboxylesterase 1F
chr12_-_38274036 7.17 ENSRNOT00000063990
kinetochore associated 1
chr6_+_29012007 7.14 ENSRNOT00000085612
ATPase family, AAA domain containing 2B
chr3_+_72385666 7.12 ENSRNOT00000011168
proteoglycan 2
chr8_-_7426611 7.05 ENSRNOT00000031492
Rho GTPase activating protein 42
chr6_+_107517668 6.97 ENSRNOT00000013753
acyl-CoA thioesterase 4
chr5_-_76632462 6.95 ENSRNOT00000085109
sushi domain containing 1
chr10_-_13898855 6.91 ENSRNOT00000004249
RAB26, member RAS oncogene family
chr1_-_80185882 6.89 ENSRNOT00000022214
vasodilator-stimulated phosphoprotein
chr9_-_14599594 6.88 ENSRNOT00000018138
triggering receptor expressed on myeloid cells-like 1
chr20_-_41209728 6.87 ENSRNOT00000000657
5'-nucleotidase domain containing 1
chr18_-_69784099 6.87 ENSRNOT00000049759
malic enzyme 2
chr10_-_57064600 6.87 ENSRNOT00000032926
C-X-C motif chemokine ligand 16
chr1_-_261986759 6.86 ENSRNOT00000021257
pyridine nucleotide-disulphide oxidoreductase domain 2
chr1_-_98570949 6.83 ENSRNOT00000033648
sialic acid binding Ig-like lectin 5
chr6_-_91518996 6.82 ENSRNOT00000005835
DNA polymerase epsilon 2, accessory subunit
chr1_+_91857057 6.79 ENSRNOT00000077993
ENSRNOT00000081465
ankyrin repeat domain 27
chr4_+_34282625 6.76 ENSRNOT00000011138
ENSRNOT00000086735
glucocorticoid induced 1
chr4_-_34282351 6.74 ENSRNOT00000011123
replication protein A3
chr19_+_58746313 6.72 ENSRNOT00000026986
mitogen-activated protein kinase kinase kinase 21
chr20_-_5192000 6.69 ENSRNOT00000079677
tumor necrosis factor
chr4_-_70747226 6.61 ENSRNOT00000044960
anionic trypsin-2-like
chr4_-_77489535 6.60 ENSRNOT00000008728
protein disulfide isomerase family A, member 4
chr20_+_3351303 6.60 ENSRNOT00000080419
ENSRNOT00000001065
ENSRNOT00000086503
alpha tubulin acetyltransferase 1
chr1_+_279798187 6.57 ENSRNOT00000024065
pancreatic lipase
chr3_+_11554457 6.56 ENSRNOT00000073087
family with sequence similarity 102, member A
chr4_-_163214678 6.55 ENSRNOT00000091602
C-type lectin domain family 1, member A
chr5_-_152358643 6.51 ENSRNOT00000021734
SH3 domain binding glutamate-rich protein like 3
chr3_+_111422267 6.51 ENSRNOT00000052312
nucleolar and spindle associated protein 1
chr1_+_260093641 6.48 ENSRNOT00000019521
cyclin J
chr2_-_27500654 6.45 ENSRNOT00000022055
3-hydroxy-3-methylglutaryl-CoA reductase
chr2_-_182038178 6.43 ENSRNOT00000040708
fibrinogen beta chain
chr5_-_164348713 6.37 ENSRNOT00000087044
similar to casein kinase 1, gamma 3 isoform 2
chr10_+_73333119 6.35 ENSRNOT00000004736
T-box 4
chr10_-_62287189 6.30 ENSRNOT00000004365
WD repeat domain 81
chr1_+_88885937 6.27 ENSRNOT00000029719
NFKB inhibitor delta
chr10_-_109840047 6.26 ENSRNOT00000054947
NOTUM, palmitoleoyl-protein carboxylesterase
chr9_-_9985630 6.25 ENSRNOT00000071780
crumbs 3, cell polarity complex component
chr1_-_98521551 6.24 ENSRNOT00000081922
sialic acid binding Ig-like lectin 10
chr11_-_77593171 6.22 ENSRNOT00000002645
ENSRNOT00000043498
interleukin 1 receptor accessory protein
chr10_+_88987558 6.21 ENSRNOT00000026878
hydroxysteroid (17-beta) dehydrogenase 1
chr3_-_3700200 6.17 ENSRNOT00000036231

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp524

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.5 25.5 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
5.5 22.1 GO:0050904 diapedesis(GO:0050904)
5.5 16.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
5.4 16.3 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223) negative regulation of natural killer cell chemotaxis(GO:2000502)
5.4 16.3 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
5.3 16.0 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
5.3 26.6 GO:0048550 negative regulation of pinocytosis(GO:0048550)
5.3 78.8 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
5.1 25.5 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
4.9 9.8 GO:0002585 positive regulation of antigen processing and presentation of peptide antigen(GO:0002585)
4.7 18.8 GO:0033277 abortive mitotic cell cycle(GO:0033277)
4.6 13.8 GO:0002777 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780) detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419)
4.1 12.3 GO:1901227 negative regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901227)
3.8 11.5 GO:0000053 argininosuccinate metabolic process(GO:0000053)
3.8 19.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
3.8 11.3 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
3.8 11.3 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
3.7 11.1 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
3.7 14.7 GO:0015746 citrate transport(GO:0015746)
3.6 25.5 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
3.6 10.9 GO:0016129 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
3.6 14.4 GO:0007386 compartment pattern specification(GO:0007386)
3.5 10.5 GO:1990743 protein sialylation(GO:1990743)
3.4 24.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
3.4 13.7 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
3.3 19.8 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
3.3 19.7 GO:0042414 epinephrine metabolic process(GO:0042414)
3.2 9.6 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
3.1 15.5 GO:0061144 alveolar secondary septum development(GO:0061144)
3.0 12.1 GO:1903576 response to L-arginine(GO:1903576)
3.0 17.8 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
2.9 8.8 GO:1903769 negative regulation of cell proliferation in bone marrow(GO:1903769)
2.9 8.7 GO:0010813 neuropeptide catabolic process(GO:0010813)
2.7 8.0 GO:0019417 sulfur oxidation(GO:0019417)
2.7 10.7 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
2.6 7.8 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
2.6 18.1 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
2.5 10.1 GO:0007296 vitellogenesis(GO:0007296)
2.5 27.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
2.5 10.0 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
2.5 12.5 GO:0006566 threonine metabolic process(GO:0006566)
2.5 5.0 GO:0019042 viral latency(GO:0019042) release from viral latency(GO:0019046)
2.5 9.8 GO:0015879 carnitine transport(GO:0015879)
2.5 7.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
2.4 12.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
2.4 7.2 GO:0006543 glutamine catabolic process(GO:0006543)
2.4 7.1 GO:0002215 defense response to nematode(GO:0002215)
2.3 7.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
2.3 11.7 GO:0097332 response to antipsychotic drug(GO:0097332)
2.3 11.4 GO:0015801 aromatic amino acid transport(GO:0015801)
2.3 6.8 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
2.2 6.6 GO:0071929 alpha-tubulin acetylation(GO:0071929)
2.1 4.2 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
2.1 16.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
2.1 6.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
2.1 8.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
2.1 8.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
2.0 6.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
2.0 6.0 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
2.0 6.0 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
1.9 7.6 GO:0034421 post-translational protein acetylation(GO:0034421)
1.9 9.5 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
1.9 5.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
1.8 27.5 GO:0002024 diet induced thermogenesis(GO:0002024)
1.8 14.5 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
1.8 5.4 GO:2000864 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
1.8 7.2 GO:1903334 positive regulation of protein folding(GO:1903334)
1.7 10.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
1.7 5.1 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
1.7 28.6 GO:0036297 interstrand cross-link repair(GO:0036297)
1.7 11.8 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
1.7 5.0 GO:0006407 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407)
1.6 13.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
1.6 14.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
1.6 9.3 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
1.5 1.5 GO:0044783 G1 DNA damage checkpoint(GO:0044783)
1.5 13.4 GO:0070314 G1 to G0 transition(GO:0070314)
1.5 4.4 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.5 21.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
1.4 5.7 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
1.4 4.3 GO:0033123 positive regulation of purine nucleotide catabolic process(GO:0033123)
1.4 8.6 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.4 5.7 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.4 13.7 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
1.4 4.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
1.4 13.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
1.4 4.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
1.4 4.1 GO:0042891 antibiotic transport(GO:0042891)
1.4 6.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
1.4 2.7 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
1.3 5.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.3 6.6 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
1.3 10.4 GO:0019388 galactose catabolic process(GO:0019388)
1.3 6.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.3 21.9 GO:0042415 norepinephrine metabolic process(GO:0042415)
1.3 3.8 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
1.3 3.8 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
1.3 6.3 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
1.2 7.5 GO:1901525 negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
1.2 3.7 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
1.2 9.9 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
1.2 6.2 GO:0016078 tRNA catabolic process(GO:0016078)
1.2 8.6 GO:0001922 B-1 B cell homeostasis(GO:0001922)
1.2 4.8 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
1.2 3.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
1.2 5.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.2 3.5 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
1.2 4.6 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
1.1 4.6 GO:1903575 cornified envelope assembly(GO:1903575)
1.1 7.8 GO:0048227 plasma membrane to endosome transport(GO:0048227)
1.1 5.5 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.1 7.5 GO:0007144 female meiosis I(GO:0007144)
1.1 7.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
1.1 15.0 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
1.1 5.3 GO:1903236 regulation of leukocyte tethering or rolling(GO:1903236)
1.1 7.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
1.1 15.9 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
1.1 5.3 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
1.0 2.1 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
1.0 10.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
1.0 4.0 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
1.0 4.0 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
1.0 12.0 GO:0045059 positive thymic T cell selection(GO:0045059)
1.0 4.8 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.9 6.6 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.9 1.9 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.9 3.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.9 2.7 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.9 8.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.9 1.8 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.9 24.8 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.9 17.6 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.9 2.6 GO:0043606 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) formamide metabolic process(GO:0043606)
0.9 6.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.9 6.0 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.9 6.9 GO:0006108 malate metabolic process(GO:0006108)
0.8 4.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.8 16.8 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.8 2.5 GO:0010070 zygote asymmetric cell division(GO:0010070)
0.8 12.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.8 10.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.8 2.3 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.8 4.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.8 6.9 GO:0010818 T cell chemotaxis(GO:0010818)
0.8 2.3 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.7 3.0 GO:0018992 germ-line sex determination(GO:0018992)
0.7 2.9 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.7 1.5 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
0.7 11.6 GO:0045056 transcytosis(GO:0045056)
0.7 10.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.7 3.5 GO:0038203 TORC2 signaling(GO:0038203)
0.7 6.3 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.7 4.9 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.7 6.2 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.7 4.8 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.7 12.9 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.7 10.8 GO:0042574 retinal metabolic process(GO:0042574)
0.7 3.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.7 2.6 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.7 5.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.7 4.6 GO:0000103 sulfate assimilation(GO:0000103)
0.6 1.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.6 10.0 GO:0030149 sphingolipid catabolic process(GO:0030149)
0.6 3.7 GO:0070914 UV-damage excision repair(GO:0070914)
0.6 3.7 GO:0006069 ethanol oxidation(GO:0006069)
0.6 3.1 GO:0035627 ceramide transport(GO:0035627)
0.6 3.0 GO:0015074 DNA integration(GO:0015074)
0.6 1.2 GO:0097694 establishment of RNA localization to telomere(GO:0097694)
0.6 7.9 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.6 10.2 GO:0006743 ubiquinone metabolic process(GO:0006743)
0.6 11.4 GO:0019068 virion assembly(GO:0019068)
0.6 3.0 GO:0051036 regulation of endosome size(GO:0051036)
0.6 9.4 GO:0043950 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642) positive regulation of cAMP-mediated signaling(GO:0043950)
0.6 1.7 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
0.6 2.3 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.6 2.9 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.6 5.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.6 3.4 GO:0001302 replicative cell aging(GO:0001302)
0.6 3.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.6 3.3 GO:0006983 ER overload response(GO:0006983)
0.6 1.7 GO:0040009 regulation of growth rate(GO:0040009)
0.5 3.3 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.5 8.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.5 3.3 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.5 5.3 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.5 1.0 GO:1990268 response to gold nanoparticle(GO:1990268)
0.5 2.6 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.5 6.2 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.5 1.5 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.5 9.2 GO:0030903 notochord development(GO:0030903)
0.5 7.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.5 4.4 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.5 3.9 GO:0072718 response to cisplatin(GO:0072718)
0.5 4.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.5 6.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.5 8.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.5 4.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.5 1.9 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.5 4.7 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.5 2.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.5 1.8 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.5 5.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.5 10.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 1.8 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.4 3.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.4 5.7 GO:0070989 oxidative demethylation(GO:0070989)
0.4 5.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.4 11.9 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.4 5.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.4 4.6 GO:0032367 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.4 0.8 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.4 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.4 3.3 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.4 4.1 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.4 5.7 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.4 3.6 GO:0099562 maintenance of postsynaptic specialization structure(GO:0098880) maintenance of postsynaptic density structure(GO:0099562)
0.4 1.6 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.4 12.2 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
0.4 4.7 GO:1990403 embryonic brain development(GO:1990403)
0.4 1.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.4 2.3 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.4 3.5 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.4 27.2 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.4 12.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.4 1.5 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.4 5.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.4 1.8 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.4 1.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.4 4.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.4 1.1 GO:0002462 tolerance induction to nonself antigen(GO:0002462)
0.4 20.4 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.3 1.0 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.3 1.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.3 2.6 GO:0006021 inositol biosynthetic process(GO:0006021)
0.3 1.9 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.3 3.2 GO:0008343 adult feeding behavior(GO:0008343)
0.3 8.0 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.3 10.0 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.3 9.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.3 1.5 GO:0044691 tooth eruption(GO:0044691)
0.3 4.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.3 3.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3 3.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.3 7.3 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.3 4.1 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.3 24.0 GO:0019882 antigen processing and presentation(GO:0019882)
0.3 4.3 GO:0002347 response to tumor cell(GO:0002347)
0.3 5.4 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.3 1.4 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.3 1.4 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3 2.8 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.3 2.8 GO:0006465 signal peptide processing(GO:0006465)
0.3 18.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.3 5.5 GO:0006298 mismatch repair(GO:0006298)
0.3 7.2 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.3 0.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.3 2.5 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.3 3.5 GO:0034389 lipid particle organization(GO:0034389)
0.3 0.8 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.3 1.9 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.3 5.8 GO:0006691 leukotriene metabolic process(GO:0006691)
0.3 0.5 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.3 1.6 GO:0098885 modification of postsynaptic actin cytoskeleton(GO:0098885)
0.2 5.0 GO:0007567 parturition(GO:0007567)
0.2 1.9 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.2 6.1 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.5 GO:0071440 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.2 0.9 GO:0009826 unidimensional cell growth(GO:0009826)
0.2 3.0 GO:0015816 glycine transport(GO:0015816)
0.2 1.7 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 1.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.2 0.9 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 5.0 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.2 2.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.2 10.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.2 3.7 GO:0006999 nuclear pore organization(GO:0006999)
0.2 2.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 3.3 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.2 0.8 GO:0006014 D-ribose metabolic process(GO:0006014)
0.2 4.5 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.2 0.6 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.2 0.8 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.2 5.6 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.2 0.8 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.2 1.1 GO:0060017 parathyroid gland development(GO:0060017)
0.2 1.1 GO:0044351 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) macropinocytosis(GO:0044351)
0.2 1.7 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.2 2.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.2 2.5 GO:2000641 regulation of early endosome to late endosome transport(GO:2000641)
0.2 1.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.2 6.8 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.2 4.7 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.2 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.5 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.2 3.4 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.2 4.6 GO:0009651 response to salt stress(GO:0009651)
0.2 8.0 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 3.5 GO:0097320 membrane tubulation(GO:0097320)
0.2 4.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 8.6 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.2 0.3 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909)
0.1 1.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 6.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 5.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 2.8 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 1.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 1.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 6.9 GO:0030168 platelet activation(GO:0030168)
0.1 1.9 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 3.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 9.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 1.6 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 1.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.6 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.1 11.0 GO:0007586 digestion(GO:0007586)
0.1 2.2 GO:0016180 snRNA processing(GO:0016180)
0.1 11.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 1.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 5.1 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 0.9 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 5.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 2.0 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 3.5 GO:0032092 positive regulation of protein binding(GO:0032092)
0.1 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 2.0 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 0.5 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 3.7 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 1.6 GO:0042119 neutrophil activation(GO:0042119)
0.1 2.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 1.9 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.1 3.8 GO:0048144 fibroblast proliferation(GO:0048144)
0.1 3.9 GO:0043966 histone H3 acetylation(GO:0043966)
0.1 1.5 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 1.6 GO:0007032 endosome organization(GO:0007032)
0.1 2.2 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 1.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.4 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.1 0.3 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.1 2.7 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 3.2 GO:0016575 histone deacetylation(GO:0016575)
0.1 3.3 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.6 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 0.9 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 3.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 0.3 GO:0006311 meiotic gene conversion(GO:0006311) male meiosis chromosome segregation(GO:0007060) gene conversion(GO:0035822)
0.1 2.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 7.6 GO:0048705 skeletal system morphogenesis(GO:0048705)
0.0 0.7 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 1.3 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.9 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 5.6 GO:0051607 defense response to virus(GO:0051607)
0.0 4.1 GO:1900180 regulation of protein localization to nucleus(GO:1900180)
0.0 0.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 1.0 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.1 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0 0.9 GO:0006400 tRNA modification(GO:0006400)
0.0 0.8 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 2.1 GO:0016042 lipid catabolic process(GO:0016042)
0.0 3.0 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.0 0.5 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 1.3 GO:0006333 chromatin assembly or disassembly(GO:0006333)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 55.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
3.9 11.8 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
3.5 24.4 GO:0042825 TAP complex(GO:0042825)
3.4 20.2 GO:1990111 spermatoproteasome complex(GO:1990111)
3.1 9.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
2.5 17.8 GO:0005579 membrane attack complex(GO:0005579)
2.4 7.2 GO:1990423 RZZ complex(GO:1990423)
1.8 16.5 GO:0016461 unconventional myosin complex(GO:0016461)
1.6 6.6 GO:0097427 microtubule bundle(GO:0097427)
1.6 11.2 GO:0001652 granular component(GO:0001652)
1.6 7.9 GO:0097165 nuclear stress granule(GO:0097165)
1.5 8.7 GO:0033093 Weibel-Palade body(GO:0033093)
1.4 4.3 GO:0044611 nuclear pore inner ring(GO:0044611)
1.4 4.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
1.4 9.7 GO:0060205 cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
1.4 6.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.3 4.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.3 4.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.3 11.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.3 3.8 GO:0008537 proteasome activator complex(GO:0008537)
1.2 5.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.2 7.1 GO:0031904 endosome lumen(GO:0031904)
1.2 10.5 GO:0000138 Golgi trans cisterna(GO:0000138)
1.1 6.8 GO:0097422 tubular endosome(GO:0097422)
1.1 6.8 GO:1990246 uniplex complex(GO:1990246)
1.1 4.5 GO:0071008 B cell receptor complex(GO:0019815) U2-type post-mRNA release spliceosomal complex(GO:0071008)
1.1 4.3 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
1.0 11.5 GO:0070852 cell body fiber(GO:0070852)
1.0 15.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.9 9.0 GO:0008290 F-actin capping protein complex(GO:0008290)
0.9 9.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.9 2.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.9 10.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.8 6.4 GO:0005577 fibrinogen complex(GO:0005577)
0.8 5.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.8 9.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.8 4.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.8 5.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.7 3.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.7 14.1 GO:0043196 varicosity(GO:0043196)
0.7 26.9 GO:0001772 immunological synapse(GO:0001772)
0.7 4.9 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.7 4.8 GO:0001739 sex chromatin(GO:0001739)
0.7 7.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.6 2.5 GO:0071203 WASH complex(GO:0071203)
0.6 1.9 GO:0005960 glycine cleavage complex(GO:0005960)
0.6 9.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.6 1.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.5 9.3 GO:0036038 MKS complex(GO:0036038)
0.5 12.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.5 8.2 GO:0030061 mitochondrial crista(GO:0030061)
0.5 12.2 GO:0034706 sodium channel complex(GO:0034706)
0.5 5.5 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.5 9.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.5 6.9 GO:0031091 platelet alpha granule(GO:0031091)
0.5 2.4 GO:0031501 mannosyltransferase complex(GO:0031501)
0.5 2.8 GO:0005787 signal peptidase complex(GO:0005787)
0.5 4.7 GO:0010369 chromocenter(GO:0010369)
0.5 4.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.4 139.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.4 5.7 GO:0042627 chylomicron(GO:0042627)
0.4 10.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.4 5.9 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.4 1.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.4 13.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.4 8.1 GO:0042588 zymogen granule(GO:0042588)
0.4 5.2 GO:0097542 ciliary tip(GO:0097542)
0.4 1.2 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.4 2.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.4 9.7 GO:0001533 cornified envelope(GO:0001533)
0.4 5.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.4 9.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.4 1.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.4 25.3 GO:0005811 lipid particle(GO:0005811)
0.4 4.2 GO:0016342 catenin complex(GO:0016342)
0.4 3.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.4 5.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.3 27.0 GO:0031526 brush border membrane(GO:0031526)
0.3 23.9 GO:0032587 ruffle membrane(GO:0032587)
0.3 2.4 GO:0070449 elongin complex(GO:0070449)
0.3 38.6 GO:0005884 actin filament(GO:0005884)
0.3 1.6 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.3 3.2 GO:0035102 PRC1 complex(GO:0035102)
0.3 10.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 3.9 GO:0030914 STAGA complex(GO:0030914)
0.3 2.7 GO:0043202 lysosomal lumen(GO:0043202)
0.3 5.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.3 0.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 4.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 0.8 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.3 8.0 GO:0008180 COP9 signalosome(GO:0008180)
0.3 2.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.3 3.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 3.5 GO:0031932 TORC2 complex(GO:0031932)
0.2 3.4 GO:0017119 Golgi transport complex(GO:0017119)
0.2 9.4 GO:0060170 ciliary membrane(GO:0060170)
0.2 2.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.2 12.5 GO:0030667 secretory granule membrane(GO:0030667)
0.2 27.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 31.1 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.2 1.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.2 0.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 15.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 2.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 6.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 5.2 GO:0051233 spindle midzone(GO:0051233)
0.2 4.7 GO:0000421 autophagosome membrane(GO:0000421)
0.2 2.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.2 3.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 1.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 2.5 GO:0030904 retromer complex(GO:0030904)
0.2 0.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 6.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 8.9 GO:0005876 spindle microtubule(GO:0005876)
0.2 1.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 2.4 GO:0030057 desmosome(GO:0030057)
0.2 4.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 20.7 GO:0005923 bicellular tight junction(GO:0005923)
0.2 10.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 1.2 GO:0070187 telosome(GO:0070187)
0.2 32.7 GO:0031965 nuclear membrane(GO:0031965)
0.1 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.1 2.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 3.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 4.8 GO:0016235 aggresome(GO:0016235)
0.1 8.1 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 2.2 GO:0032039 integrator complex(GO:0032039)
0.1 3.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 4.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 4.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 16.6 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 5.4 GO:0016605 PML body(GO:0016605)
0.1 20.7 GO:0005667 transcription factor complex(GO:0005667)
0.1 2.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 4.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 3.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 4.9 GO:0001726 ruffle(GO:0001726)
0.1 1.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 3.2 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 6.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 5.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 4.8 GO:0005581 collagen trimer(GO:0005581)
0.1 3.1 GO:0005903 brush border(GO:0005903)
0.1 4.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 12.7 GO:0000790 nuclear chromatin(GO:0000790)
0.1 2.0 GO:0016592 mediator complex(GO:0016592)
0.1 1.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 13.3 GO:0016607 nuclear speck(GO:0016607)
0.0 2.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 19.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.7 GO:0005776 autophagosome(GO:0005776)
0.0 1.1 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.0 GO:0031201 SNARE complex(GO:0031201)
0.0 35.0 GO:0005654 nucleoplasm(GO:0005654)
0.0 5.3 GO:0005874 microtubule(GO:0005874)
0.0 0.3 GO:0000801 central element(GO:0000801)
0.0 2.8 GO:0000785 chromatin(GO:0000785)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.6 GO:0055037 recycling endosome(GO:0055037)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
15.8 78.8 GO:0019770 IgG receptor activity(GO:0019770)
10.0 29.9 GO:0032810 sterol response element binding(GO:0032810)
6.6 26.5 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
5.9 17.8 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
4.9 24.4 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
4.4 21.8 GO:0004103 choline kinase activity(GO:0004103)
3.9 11.7 GO:0070976 TIR domain binding(GO:0070976)
3.7 11.1 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
3.7 14.7 GO:0015137 citrate transmembrane transporter activity(GO:0015137)
3.7 11.0 GO:0004359 glutaminase activity(GO:0004359)
3.5 17.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
3.4 13.7 GO:0004967 glucagon receptor activity(GO:0004967)
3.3 10.0 GO:0004522 ribonuclease A activity(GO:0004522)
3.3 9.8 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
2.9 11.6 GO:0019960 C-X3-C chemokine binding(GO:0019960)
2.6 18.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
2.6 10.5 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
2.5 10.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
2.4 9.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
2.4 11.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
2.3 6.8 GO:0015292 uniporter activity(GO:0015292)
2.2 17.7 GO:0008172 S-methyltransferase activity(GO:0008172)
2.2 8.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
2.1 18.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.1 6.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
2.1 8.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
2.0 4.1 GO:0042895 antibiotic transporter activity(GO:0042895)
2.0 14.3 GO:0048019 receptor antagonist activity(GO:0048019)
2.0 14.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
2.0 24.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
2.0 6.0 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
2.0 13.8 GO:0050700 CARD domain binding(GO:0050700)
2.0 5.9 GO:0008481 sphinganine kinase activity(GO:0008481)
1.9 7.8 GO:0005143 interleukin-12 receptor binding(GO:0005143)
1.9 13.4 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
1.9 5.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.9 11.4 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
1.9 5.6 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.9 5.6 GO:0004046 aminoacylase activity(GO:0004046)
1.8 5.5 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
1.8 8.8 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
1.8 15.9 GO:0032052 bile acid binding(GO:0032052)
1.7 13.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.7 6.9 GO:0019002 GMP binding(GO:0019002)
1.7 6.7 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
1.7 6.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
1.7 11.6 GO:0030492 hemoglobin binding(GO:0030492)
1.6 4.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.6 11.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
1.6 19.4 GO:0004955 prostaglandin receptor activity(GO:0004955)
1.6 12.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.6 4.8 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
1.6 6.2 GO:0070401 NADP+ binding(GO:0070401) estradiol binding(GO:1903924)
1.6 9.3 GO:0004994 somatostatin receptor activity(GO:0004994)
1.5 4.6 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
1.4 4.2 GO:0031893 vasopressin receptor binding(GO:0031893)
1.4 20.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.4 5.5 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
1.4 4.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
1.4 12.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
1.3 4.0 GO:0000171 ribonuclease MRP activity(GO:0000171)
1.3 28.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
1.3 26.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.3 17.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
1.2 3.7 GO:0005503 all-trans retinal binding(GO:0005503) benzaldehyde dehydrogenase activity(GO:0019115) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
1.2 5.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
1.2 16.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
1.2 11.7 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.2 3.5 GO:0019961 interferon binding(GO:0019961)
1.2 8.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
1.1 6.9 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
1.1 4.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
1.1 19.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
1.0 5.1 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-dependent protein binding(GO:0032767) copper-transporting ATPase activity(GO:0043682)
1.0 9.0 GO:0042285 xylosyltransferase activity(GO:0042285)
1.0 3.0 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.0 10.7 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
1.0 4.9 GO:0001007 transcription factor activity, RNA polymerase III transcription factor binding(GO:0001007) transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.0 19.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.9 3.7 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.9 3.7 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.9 5.5 GO:0048039 ubiquinone binding(GO:0048039)
0.9 3.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.9 2.7 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.9 5.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.9 11.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.9 2.7 GO:0070905 serine binding(GO:0070905)
0.9 10.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.8 2.5 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.8 2.5 GO:1990460 leptin receptor binding(GO:1990460)
0.8 3.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.8 0.8 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.8 16.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.8 22.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.8 4.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923) GPI anchor binding(GO:0034235)
0.8 6.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.7 3.7 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.7 10.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.7 1.5 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.7 3.7 GO:0005550 pheromone binding(GO:0005550)
0.7 4.3 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.7 4.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.7 6.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.7 4.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.7 15.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.6 2.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.6 10.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6 5.7 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.6 6.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.6 5.0 GO:0030957 Tat protein binding(GO:0030957)
0.6 7.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.6 12.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.6 9.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.6 9.7 GO:0019215 intermediate filament binding(GO:0019215)
0.6 4.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.6 11.5 GO:0015643 toxic substance binding(GO:0015643)
0.6 1.8 GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity(GO:0017168)
0.6 1.2 GO:0031177 phosphopantetheine binding(GO:0031177)
0.6 2.3 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.6 10.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.6 2.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.5 3.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.5 2.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.5 7.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.5 3.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.5 4.3 GO:0046870 cadmium ion binding(GO:0046870)
0.5 4.3 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.5 2.1 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.5 1.6 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.5 16.9 GO:0017025 TBP-class protein binding(GO:0017025)
0.5 11.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.5 1.5 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.5 5.1 GO:0051766 inositol trisphosphate kinase activity(GO:0051766)
0.5 5.6 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.5 6.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.5 6.5 GO:0070402 NADPH binding(GO:0070402)
0.5 2.9 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.5 5.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.5 12.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.5 3.3 GO:0042608 T cell receptor binding(GO:0042608)
0.5 6.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.5 2.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.5 4.1 GO:0005113 patched binding(GO:0005113)
0.4 11.6 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.4 5.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.4 5.7 GO:0098919 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of synapse(GO:0098918) structural constituent of postsynaptic density(GO:0098919)
0.4 1.7 GO:0019237 centromeric DNA binding(GO:0019237)
0.4 8.0 GO:0071949 FAD binding(GO:0071949)
0.4 10.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.4 1.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.4 1.7 GO:0019776 Atg8 ligase activity(GO:0019776)
0.4 22.2 GO:0000049 tRNA binding(GO:0000049)
0.4 27.3 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.4 5.9 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.4 8.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.4 4.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 1.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.4 8.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.3 4.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3 8.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.3 11.0 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.3 6.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 6.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.3 2.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.3 1.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.3 9.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 3.7 GO:0042301 phosphate ion binding(GO:0042301)
0.3 1.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 1.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 3.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.3 5.1 GO:0001972 retinoic acid binding(GO:0001972)
0.3 12.2 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.3 1.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.3 5.8 GO:0005112 Notch binding(GO:0005112)
0.3 9.5 GO:0032451 demethylase activity(GO:0032451)
0.3 20.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.3 35.3 GO:0017124 SH3 domain binding(GO:0017124)
0.3 7.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.3 5.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 4.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.3 2.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.3 2.1 GO:0043495 protein anchor(GO:0043495)
0.3 6.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 6.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 7.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 4.7 GO:0070717 poly-purine tract binding(GO:0070717)
0.2 10.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.2 13.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.2 2.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 6.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 1.8 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 1.6 GO:0050897 cobalt ion binding(GO:0050897)
0.2 2.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.2 7.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.2 9.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.2 28.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 13.1 GO:0035326 enhancer binding(GO:0035326)
0.2 5.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 3.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 9.3 GO:0003684 damaged DNA binding(GO:0003684)
0.2 1.5 GO:0060229 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.2 4.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.2 6.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 8.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 6.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.2 19.0 GO:0001047 core promoter binding(GO:0001047)
0.2 23.0 GO:0042393 histone binding(GO:0042393)
0.2 14.1 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.2 5.8 GO:0070330 aromatase activity(GO:0070330)
0.1 2.1 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 2.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.9 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 3.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 0.6 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.1 1.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.8 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 1.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 3.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 4.6 GO:0015485 cholesterol binding(GO:0015485)
0.1 1.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 1.9 GO:0015026 coreceptor activity(GO:0015026)
0.1 3.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 2.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 10.9 GO:0005178 integrin binding(GO:0005178)
0.1 2.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 2.5 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.1 GO:0004875 complement receptor activity(GO:0004875)
0.1 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 2.5 GO:0008483 transaminase activity(GO:0008483)
0.1 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.9 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 1.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 18.0 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 4.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 3.9 GO:0019003 GDP binding(GO:0019003)
0.1 0.2 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 2.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.3 GO:0050699 WW domain binding(GO:0050699)
0.1 1.4 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 1.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 15.9 GO:0003712 transcription cofactor activity(GO:0003712)
0.1 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 15.1 GO:0030246 carbohydrate binding(GO:0030246)
0.1 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 4.2 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.9 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.6 GO:0043176 amine binding(GO:0043176)
0.0 9.2 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 5.5 GO:0003924 GTPase activity(GO:0003924)
0.0 1.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.6 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 2.6 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0004177 aminopeptidase activity(GO:0004177)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 68.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.9 123.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
1.5 33.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.9 22.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.9 13.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.8 25.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.8 14.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.8 9.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.7 23.8 PID IL1 PATHWAY IL1-mediated signaling events
0.7 29.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.7 17.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.6 13.7 PID RAS PATHWAY Regulation of Ras family activation
0.6 10.7 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.6 17.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.6 3.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.6 8.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.5 14.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.4 10.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.4 7.8 PID IL27 PATHWAY IL27-mediated signaling events
0.4 15.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.4 17.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4 6.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.3 1.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 4.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 7.9 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.3 14.8 PID FGF PATHWAY FGF signaling pathway
0.3 2.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.3 9.4 PID BARD1 PATHWAY BARD1 signaling events
0.3 23.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.3 18.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.3 11.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 8.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 2.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 5.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 3.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.2 9.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 4.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 2.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.2 3.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 2.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 3.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 3.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 4.3 PID AP1 PATHWAY AP-1 transcription factor network
0.1 6.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 1.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 4.2 PID E2F PATHWAY E2F transcription factor network
0.1 3.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 5.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 3.6 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 56.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
3.5 157.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
3.1 18.8 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
2.4 19.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
1.9 13.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
1.9 44.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
1.6 21.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
1.5 10.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
1.3 11.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.2 20.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
1.1 16.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
1.0 34.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
1.0 13.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.9 31.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.9 11.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.9 20.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.9 9.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.9 16.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.8 11.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.8 6.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.8 7.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.8 13.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.8 4.6 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.7 11.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.7 12.4 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.7 23.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.7 8.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.6 11.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.6 35.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.6 10.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.6 6.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.6 16.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.6 13.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.6 3.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.6 16.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.6 7.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.5 22.7 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.5 18.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.5 14.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.5 19.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.5 8.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.5 12.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.5 6.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.5 5.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.4 9.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.4 21.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.4 8.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.4 6.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.4 4.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.4 3.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.4 6.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.4 9.6 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.4 24.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.4 4.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 10.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.3 8.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.3 12.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 10.7 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.3 3.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.3 1.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 15.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 4.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 7.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 5.0 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.2 17.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 4.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 9.0 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.2 3.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.2 5.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 3.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 3.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 2.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 0.9 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.2 2.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 2.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 4.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.2 23.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 10.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 9.8 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2 1.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 1.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 2.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 17.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 5.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 3.1 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 1.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 5.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 4.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 4.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.1 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 2.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 2.5 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation