ISMARA results: Zfp384

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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfp384

Z-value: 1.30

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Transcription factors associated with Zfp384

Gene Symbol	Gene ID	Gene Info
Zfp384 NCBI RGD Ensembl	ENSRNOG00000017066	zinc finger protein 384

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Zfp384	rn6_v1_chr4_+_157523320_157523320	0.65	4.2e-40	Click!

Activity profile of Zfp384 motif

Sorted Z-values of Zfp384 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_+_86094567 Show fit	41.62	ENSRNOT00000086514	LOC100361706 NCBI RGD Ensembl Show fit	lambda-chain C1-region-like
chr2_+_223029559 Show fit	25.84	ENSRNOT00000045584	AABR07013111.1 NCBI RGD Ensembl Show fit
chr4_+_69457472 Show fit	25.05	ENSRNOT00000067597	Trbv19 NCBI RGD Ensembl Show fit	T cell receptor beta, variable 19
chr6_-_138632159 Show fit	23.46	ENSRNOT00000082921 ENSRNOT00000040702	Ighm NCBI RGD Ensembl Show fit	immunoglobulin heavy constant mu
chr17_+_43423111 Show fit	22.94	ENSRNOT00000022630	Hist1h2ba NCBI RGD Ensembl Show fit	histone cluster 1 H2B family member a
chr17_+_43734461 Show fit	21.57	ENSRNOT00000072564	Hist1h1d NCBI RGD Ensembl Show fit	histone cluster 1, H1d
chr17_-_43422846 Show fit	21.07	ENSRNOT00000050526	Hist1h2aa NCBI RGD Ensembl Show fit	histone cluster 1 H2A family member a
chr17_-_44748188 Show fit	20.99	ENSRNOT00000081970	LOC103690190 NCBI RGD Ensembl Show fit	histone H2A type 1-E
chr1_-_16687817 Show fit	20.93	ENSRNOT00000091376 ENSRNOT00000081620	Myb NCBI RGD Ensembl Show fit	MYB proto-oncogene, transcription factor
chr17_+_44760056 Show fit	20.89	ENSRNOT00000052073	LOC690171 NCBI RGD Ensembl Show fit	similar to H3 histone, family 3B

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp384

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.7	136.4	GO:0006342	chromatin silencing(GO:0006342)
1.8	125.4	GO:0006334	nucleosome assembly(GO:0006334)
2.0	53.4	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
6.4	50.9	GO:0016584	nucleosome positioning(GO:0016584)
0.7	28.1	GO:0051310	metaphase plate congression(GO:0051310)
2.2	26.3	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
8.7	26.0	GO:2000620	positive regulation of histone H4-K16 acetylation(GO:2000620)
3.8	22.9	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.8	22.9	GO:0006270	DNA replication initiation(GO:0006270)
0.6	22.2	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)

Showing 1 to 10 of 591 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
4.1	404.0	GO:0000786	nucleosome(GO:0000786)
0.2	171.3	GO:0005730	nucleolus(GO:0005730)
0.3	74.4	GO:0009897	external side of plasma membrane(GO:0009897)
0.7	52.8	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.4	38.2	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
12.2	36.7	GO:0032173	septin collar(GO:0032173)
0.1	32.9	GO:0005694	chromosome(GO:0005694)
0.8	31.2	GO:0098636	protein complex involved in cell adhesion(GO:0098636)
1.8	29.5	GO:0042613	MHC class II protein complex(GO:0042613)
0.4	29.2	GO:0071013	catalytic step 2 spliceosome(GO:0071013)

Showing 1 to 10 of 233 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	233.4	GO:0046982	protein heterodimerization activity(GO:0046982)
0.6	124.5	GO:0042393	histone binding(GO:0042393)
0.0	81.5	GO:0003676	nucleic acid binding(GO:0003676)
0.2	53.0	GO:0003735	structural constituent of ribosome(GO:0003735)
0.2	45.1	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.7	41.5	GO:0003684	damaged DNA binding(GO:0003684)
0.2	39.1	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.4	34.6	GO:0031490	chromatin DNA binding(GO:0031490)
2.2	26.3	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	24.8	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)

Showing 1 to 10 of 353 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.8	86.0	PID FOXM1 PATHWAY	FOXM1 transcription factor network
1.0	65.5	PID AP1 PATHWAY	AP-1 transcription factor network
1.4	49.4	PID AURORA A PATHWAY	Aurora A signaling
0.8	41.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.6	36.1	PID E2F PATHWAY	E2F transcription factor network
1.0	27.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.7	25.1	PID AURORA B PATHWAY	Aurora B signaling
0.6	24.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.8	24.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.6	24.3	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events

Showing 1 to 10 of 89 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
5.3	138.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
1.6	70.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.6	63.3	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
2.2	58.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.6	49.3	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
4.3	47.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
2.0	47.1	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3	30.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
1.7	29.6	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
2.2	26.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors

Showing 1 to 10 of 131 entries

Results for Zfp384

Z-value: 1.30

Motif logo

Transcription factors associated with Zfp384

Activity-expression correlation:

Activity profile of Zfp384 motif

Sorted Z-values of Zfp384 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp384

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: