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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfp148

Z-value: 1.15

Motif logo

Transcription factors associated with Zfp148

Gene Symbol Gene ID Gene Info
ENSRNOG00000001789 zinc finger protein 148

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp148rn6_v1_chr11_-_70618347_706183470.461.7e-18Click!

Activity profile of Zfp148 motif

Sorted Z-values of Zfp148 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_113257688 38.74 ENSRNOT00000019320
microtubule-associated protein 1A
chr2_-_29768750 37.25 ENSRNOT00000023460
microtubule-associated protein 1B
chr14_-_18839420 37.16 ENSRNOT00000034090
chemokine (C-X-C motif) ligand 3
chr7_+_133400485 36.71 ENSRNOT00000006219
contactin 1
chr1_-_81881549 32.09 ENSRNOT00000027497
ATPase Na+/K+ transporting subunit alpha 3
chr16_+_10417185 30.56 ENSRNOT00000082186
annexin A8
chr16_-_20686317 30.52 ENSRNOT00000060097
cytokine receptor-like factor 1
chr10_+_91710495 29.64 ENSRNOT00000033276
reprimo-like
chr16_+_3851270 27.26 ENSRNOT00000014964
placenta-specific 9
chrX_+_39711201 26.90 ENSRNOT00000080512
ENSRNOT00000009802
connector enhancer of kinase suppressor of Ras 2
chr1_-_89483988 25.06 ENSRNOT00000028603
FXYD domain-containing ion transport regulator 7
chr14_+_84306466 24.86 ENSRNOT00000006116
SEC14-like lipid binding 4
chr10_-_90999506 22.75 ENSRNOT00000034401
glial fibrillary acidic protein
chr4_+_56711049 22.53 ENSRNOT00000027237
filamin C
chr4_+_21317695 22.39 ENSRNOT00000007572
glutamate metabotropic receptor 3
chr1_-_215536980 21.10 ENSRNOT00000027344
interferon induced transmembrane protein 10
chr2_+_54191538 20.75 ENSRNOT00000019524
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr4_+_56711275 20.67 ENSRNOT00000088149
filamin C
chr1_-_7480825 20.67 ENSRNOT00000048754
phosphatase and actin regulator 2
chr8_+_59278262 20.29 ENSRNOT00000017053
DnaJ heat shock protein family (Hsp40) member A4
chr4_-_14490446 19.61 ENSRNOT00000009132
semaphorin 3C
chr5_-_109651730 19.39 ENSRNOT00000093032
ELAV like RNA binding protein 2
chr5_+_147323240 18.89 ENSRNOT00000047152
fibronectin type III domain containing 5
chr5_-_141242131 18.62 ENSRNOT00000081482
microtubule-actin crosslinking factor 1
chr9_+_118842787 18.42 ENSRNOT00000090512
DLG associated protein 1
chr10_-_61361250 17.83 ENSRNOT00000092203
RAP1 GTPase activating protein 2
chr3_+_113818872 17.48 ENSRNOT00000044158
cancer susceptibility candidate 4
chr7_-_121232741 17.22 ENSRNOT00000023196
platelet derived growth factor subunit B
chr10_-_31258105 16.63 ENSRNOT00000008544
NIPA-like domain containing 4
chr4_-_114853868 16.43 ENSRNOT00000090828
WD repeat domain 54
chr4_-_16130848 16.23 ENSRNOT00000042914
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr8_+_130283542 15.86 ENSRNOT00000071573
vasoactive intestinal peptide receptor 1
chr6_+_1657331 15.86 ENSRNOT00000049672
ENSRNOT00000079864
glutaminyl-peptide cyclotransferase
chrX_-_124464963 15.58 ENSRNOT00000036472
ENSRNOT00000077697
transmembrane protein 255A
chr7_+_70364813 15.42 ENSRNOT00000084012
ENSRNOT00000031230
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr4_-_16130563 15.10 ENSRNOT00000090240
ENSRNOT00000034969
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr11_+_86903122 14.86 ENSRNOT00000048063
zinc finger, DHHC-type containing 8
chr3_-_2689084 14.53 ENSRNOT00000020926
prostaglandin D2 synthase
chr1_-_146556171 14.42 ENSRNOT00000017636
aryl hydrocarbon receptor nuclear translocator 2
chr7_-_136853957 13.78 ENSRNOT00000008985
neural EGFL like 2
chr1_+_89491654 13.72 ENSRNOT00000028632
leucine-rich repeat LGI family, member 4
chr1_+_282265370 13.65 ENSRNOT00000015687
G protein-coupled receptor kinase 5
chr14_-_82287108 13.59 ENSRNOT00000023144
fibroblast growth factor receptor 3
chr11_+_87722350 13.41 ENSRNOT00000000313
scavenger receptor class F, member 2
chr10_+_59529785 13.41 ENSRNOT00000064840
ENSRNOT00000065181
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr1_-_239057732 13.39 ENSRNOT00000024775
guanine deaminase
chr6_+_137164535 13.39 ENSRNOT00000018225
inverted formin, FH2 and WH2 domain containing
chr14_-_36554580 13.27 ENSRNOT00000002869
RAS-like family 11 member B
chr8_-_98738446 13.13 ENSRNOT00000019860
Zic family member 1
chr6_+_76675418 12.32 ENSRNOT00000076169
ENSRNOT00000010948
ENSRNOT00000082286
breast cancer metastasis-suppressor 1-like
breast cancer metastasis-suppressor 1-like
chr2_+_188844073 11.79 ENSRNOT00000028117
potassium calcium-activated channel subfamily N member 3
chr8_+_26413233 11.20 ENSRNOT00000063967
ENSRNOT00000008838
septin 7
chr7_-_14189688 11.19 ENSRNOT00000037456
notch 3
chr8_-_59239954 11.18 ENSRNOT00000016104
acyl-CoA synthetase bubblegum family member 1
chr13_-_72744295 11.11 ENSRNOT00000093366
ENSRNOT00000077157
immediate early response 5
chr7_-_70481796 11.02 ENSRNOT00000006815
deltex E3 ubiquitin ligase 3
chr14_-_18839595 10.94 ENSRNOT00000078746
chemokine (C-X-C motif) ligand 3
chr1_-_188245628 10.89 ENSRNOT00000022800
transmembrane channel-like 7
chr19_+_2393059 10.71 ENSRNOT00000018535
cadherin 11
chr20_+_2194709 10.66 ENSRNOT00000001017
tripartite motif containing 15
chr4_-_129515435 10.51 ENSRNOT00000039353
EGF domain specific O-linked N-acetylglucosamine transferase
chr10_+_92289107 10.46 ENSRNOT00000050070
microtubule-associated protein tau
chr10_+_92288910 10.11 ENSRNOT00000006947
ENSRNOT00000045127
microtubule-associated protein tau
chr1_+_226091774 9.66 ENSRNOT00000027693
fatty acid desaturase 3
chr5_+_103479767 9.49 ENSRNOT00000008999
SH3 domain-containing GRB2-like 2
chrX_-_142131545 9.42 ENSRNOT00000077402
fibroblast growth factor 13
chrX_+_15035569 9.38 ENSRNOT00000006491
ENSRNOT00000078392
porcupine homolog (Drosophila)
chr14_+_114152472 9.32 ENSRNOT00000042965
reticulon 4
chr1_-_215536770 9.25 ENSRNOT00000078030
interferon induced transmembrane protein 10
chr2_-_144467912 9.21 ENSRNOT00000040002
cyclin A1
chr4_-_113988246 9.20 ENSRNOT00000013128
WD repeat-containing protein 54
chr8_+_118013612 8.93 ENSRNOT00000056166
microtubule-associated protein 4
chr7_-_120636563 8.83 ENSRNOT00000091317
ENSRNOT00000031117
transmembrane protein 184B
chr4_+_85662892 8.82 ENSRNOT00000016175
ENSRNOT00000043851
ENSRNOT00000035722
ENSRNOT00000046192
adenylate cyclase activating polypeptide 1 receptor type 1
chr5_-_139227196 8.74 ENSRNOT00000050941
forkhead box O6
chr6_-_137733026 8.53 ENSRNOT00000019213
jagged 2
chr5_+_59128315 8.43 ENSRNOT00000021802
natriuretic peptide receptor 2
chr10_-_39405311 8.25 ENSRNOT00000074616
PDZ and LIM domain 4
chr10_+_108340240 8.10 ENSRNOT00000077535
coiled-coil domain containing 40
chr8_-_116391158 8.07 ENSRNOT00000078720
ENSRNOT00000022550
G protein subunit alpha i2
chr1_+_157920786 7.99 ENSRNOT00000014284
family with sequence similarity 181, member B
chr17_-_55709740 7.95 ENSRNOT00000033359
similar to OTTHUMP00000046255
chr3_-_112789282 7.86 ENSRNOT00000090680
ENSRNOT00000066181
tau tubulin kinase 2
chr7_-_143738237 7.84 ENSRNOT00000055320
SPRY domain containing 3
chr19_-_58399816 7.75 ENSRNOT00000026843
signal-induced proliferation-associated 1 like 2
chr7_-_141424225 7.67 ENSRNOT00000080109
ENSRNOT00000084292
ceramide synthase 5
chr7_-_116607408 7.65 ENSRNOT00000076009
ENSRNOT00000056554
lymphocyte antigen 6 complex, locus H
chr12_+_16170162 7.39 ENSRNOT00000001686
galectin-related inter-fiber protein
chr3_-_63535991 7.25 ENSRNOT00000015722
FK506 binding protein 7
chrX_+_119030419 7.22 ENSRNOT00000060168
plastin 3
chr9_-_46401911 7.17 ENSRNOT00000046557
cellular repressor of E1A-stimulated genes 2
chr1_+_220668544 6.78 ENSRNOT00000039842
galactose-3-O-sulfotransferase 3
chr7_+_130474508 6.68 ENSRNOT00000085191
SH3 and multiple ankyrin repeat domains 3
chr1_-_103256823 6.66 ENSRNOT00000018860
protein tyrosine phosphatase, non-receptor type 5
chr8_-_125645898 6.50 ENSRNOT00000036672
RNA binding motif, single stranded interacting protein 3
chr13_+_52588917 6.42 ENSRNOT00000011999
pleckstrin homology-like domain, family A, member 3
chr14_+_36687134 6.13 ENSRNOT00000002879
ubiquitin specific peptidase 46
chr8_-_94563760 6.03 ENSRNOT00000032792
synaptosomal-associated protein 91
chr14_-_80732010 5.98 ENSRNOT00000012322
adrenoceptor alpha 2C
chr2_+_211078334 5.95 ENSRNOT00000049127
sortilin 1
chr4_-_100883275 5.93 ENSRNOT00000022846
thymosin, beta 10-like
chr7_+_41114697 5.81 ENSRNOT00000041354
ATPase plasma membrane Ca2+ transporting 1
chr8_+_117246376 5.77 ENSRNOT00000074493
coiled-coil domain containing 71
chr9_+_82674202 5.56 ENSRNOT00000027208
transmembrane protein 198
chr5_-_151072766 5.54 ENSRNOT00000078048
ENSRNOT00000017227
ENSRNOT00000085573
syntaxin 12
chr5_-_166726794 5.54 ENSRNOT00000022799
solute carrier family 25 member 33
chr7_+_130474279 5.46 ENSRNOT00000092388
SH3 and multiple ankyrin repeat domains 3
chr13_+_99173484 5.45 ENSRNOT00000080574
ENSRNOT00000088654
Left-right determination factor 2
chr4_-_100883038 5.45 ENSRNOT00000041880
thymosin, beta 10-like
chr5_+_36076565 5.39 ENSRNOT00000013599
failed axon connections homolog
chr12_+_48481750 5.35 ENSRNOT00000000886
coronin 1C
chr7_-_117680004 5.33 ENSRNOT00000040422
solute carrier family 39 member 4
chr9_+_17340341 5.24 ENSRNOT00000026637
ENSRNOT00000026559
ENSRNOT00000042790
ENSRNOT00000044163
ENSRNOT00000083811
vascular endothelial growth factor A
chr19_-_55510460 5.22 ENSRNOT00000019820
CBFA2/RUNX1 translocation partner 3
chr9_-_45292047 5.15 ENSRNOT00000083256
AF4/FMR2 family, member 3
chr4_-_118595580 5.07 ENSRNOT00000024436
annexin A4
chr19_+_40855433 5.06 ENSRNOT00000023823
interleukin 34
chr3_-_177201525 5.05 ENSRNOT00000022451
regulator of G-protein signaling 19
chr13_-_48848864 5.04 ENSRNOT00000077857
ENSRNOT00000068003
major facilitator superfamily domain containing 4
chr9_+_82647071 5.02 ENSRNOT00000027135
acid sensing ion channel subunit family member 4
chr10_+_10644572 4.99 ENSRNOT00000004026
periplakin
chr4_-_83137527 4.89 ENSRNOT00000039580
JAZF zinc finger 1
chr7_-_142132173 4.85 ENSRNOT00000026613
cysteine and serine rich nuclear protein 2
chr9_-_82673898 4.81 ENSRNOT00000027165
chondroitin polymerizing factor
chr3_-_81886545 4.79 ENSRNOT00000057007
myb-related transcription factor, partner of profilin-like
chrX_+_24891156 4.75 ENSRNOT00000071173
WWC family member 3
chr1_+_87790104 4.75 ENSRNOT00000074580
zinc finger protein 383-like
chr1_+_202432366 4.70 ENSRNOT00000027681
phospholipid phosphatase 4
chrX_+_156463953 4.41 ENSRNOT00000079889
filamin A
chr2_+_196334626 4.23 ENSRNOT00000050914
ENSRNOT00000028645
ENSRNOT00000090729
semaphorin 6C
chr6_-_27190126 4.15 ENSRNOT00000068412
ENSRNOT00000013107
potassium two pore domain channel subfamily K member 3
chr12_+_47074200 4.12 ENSRNOT00000014910
dynein light chain LC8-type 1
chr2_+_198823366 4.00 ENSRNOT00000083769
ENSRNOT00000028814
protein inhibitor of activated STAT, 3
chr2_+_62150251 3.99 ENSRNOT00000016196
zinc finger RNA binding protein
chr13_-_48284990 3.98 ENSRNOT00000086928
SLIT-ROBO Rho GTPase activating protein 2
chr12_-_41448668 3.96 ENSRNOT00000001856
RAS protein activator like 1 (GAP1 like)
chr10_-_74679858 3.92 ENSRNOT00000003859
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr4_+_114854458 3.83 ENSRNOT00000013312
hypothetical gene supported by BC079424
chr2_-_210413985 3.48 ENSRNOT00000025036
striatin interacting protein 1
chr5_+_59063531 3.46 ENSRNOT00000085311
ENSRNOT00000065909
cAMP responsive element binding protein 3
chr7_-_139318455 3.42 ENSRNOT00000092029
histone deacetylase 7
chr1_-_222734184 3.35 ENSRNOT00000049812
ENSRNOT00000028785
reticulon 3
chr17_+_9837402 3.35 ENSRNOT00000076436
RAB24, member RAS oncogene family
chr6_-_38228379 3.32 ENSRNOT00000084924
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr1_-_215836641 3.30 ENSRNOT00000080246
insulin-like growth factor 2
chr1_-_142615673 3.29 ENSRNOT00000018021
IQ motif containing GTPase activating protein 1
chr19_+_14352411 3.16 ENSRNOT00000067519
HMG-box containing 4
chr3_+_11629556 3.13 ENSRNOT00000074401
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_+_201055644 3.10 ENSRNOT00000054937
ENSRNOT00000047161
transforming, acidic coiled-coil containing protein 2
chr6_-_23581052 3.07 ENSRNOT00000006190
protein phosphatase 1 catalytic subunit beta
chr5_-_58163584 3.03 ENSRNOT00000060594
C-C motif chemokine ligand 27
chr11_+_38035611 3.01 ENSRNOT00000087603
ENSRNOT00000002695
MX dynamin like GTPase 2
chr10_+_56453877 2.98 ENSRNOT00000031640
phospholipid scramblase 3
chr10_-_6870011 2.97 ENSRNOT00000003439
similar to CG4768-PA
chr13_+_34365147 2.96 ENSRNOT00000093066
cytoplasmic linker associated protein 1
chr12_-_18540166 2.94 ENSRNOT00000001792
interleukin 3 receptor subunit alpha
chr1_+_266105124 2.90 ENSRNOT00000043925
ENSRNOT00000088243
major facilitator superfamily domain containing 13A
chr10_-_13446135 2.71 ENSRNOT00000084991
potassium channel tetramerization domain containing 5
chr20_-_3438389 2.63 ENSRNOT00000001098
ENSRNOT00000090039
flotillin 1
chr6_-_86822094 2.43 ENSRNOT00000006531
FK506 binding protein 3
chr20_-_8574082 2.39 ENSRNOT00000048845
MAM domain containing glycosylphosphatidylinositol anchor 1
chr6_+_111049559 2.37 ENSRNOT00000015571
transmembrane protein 63c
chr7_+_140716113 2.35 ENSRNOT00000033450
tubulin, alpha 1C
chr3_-_112061796 2.30 ENSRNOT00000056258
phospholipase A2 group IVD
chr15_+_33555640 2.20 ENSRNOT00000021096
poly(A) binding protein, nuclear 1
chr11_+_38035450 2.04 ENSRNOT00000083067
MX dynamin like GTPase 2
chr19_+_10119253 2.01 ENSRNOT00000017971
zinc finger protein 319
chr1_-_102849430 1.99 ENSRNOT00000086856
serum amyloid A4
chr1_-_82108083 1.92 ENSRNOT00000027677
ENSRNOT00000084530
glycogen synthase kinase 3 alpha
chr20_-_5618254 1.92 ENSRNOT00000092326
ENSRNOT00000000576
BCL2-antagonist/killer 1
chr6_+_28235695 1.90 ENSRNOT00000047210
DNA methyltransferase 3 alpha
chr17_-_14091766 1.88 ENSRNOT00000075373

chr1_+_102849889 1.78 ENSRNOT00000066791
general transcription factor IIH subunit 1
chr5_-_154223536 1.75 ENSRNOT00000012258
proline-rich nuclear receptor coactivator 2
chr10_-_85574889 1.39 ENSRNOT00000072274
hypothetical protein LOC691153
chr12_+_2069959 1.33 ENSRNOT00000001298
patatin-like phospholipase domain containing 6
chr7_+_35069814 1.31 ENSRNOT00000089228
nuclear receptor subfamily 2, group C, member 1
chr1_+_216237697 1.27 ENSRNOT00000027760
Cd81 molecule
chr10_+_93811350 1.26 ENSRNOT00000077280
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr14_-_85350786 1.17 ENSRNOT00000012634
RNA-binding protein EWS-like
chr10_+_94280703 1.13 ENSRNOT00000088656
mitogen activated protein kinase kinase kinase 3
chr2_+_62150493 1.13 ENSRNOT00000080241
zinc finger RNA binding protein
chr8_-_36467627 1.06 ENSRNOT00000082346
family with sequence similarity 118, member B
chr16_+_74292438 1.00 ENSRNOT00000026197
voltage-dependent anion channel 3
chr4_+_100407658 0.96 ENSRNOT00000018562
capping actin protein, gelsolin like
chr1_+_46378807 0.93 ENSRNOT00000043521
zinc finger, DHHC-type containing 14
chr8_-_23084879 0.92 ENSRNOT00000018874
zinc finger protein 653
chr1_+_101012822 0.89 ENSRNOT00000027809
related RAS viral (r-ras) oncogene homolog
chr7_-_144880092 0.72 ENSRNOT00000055281
nuclear factor, erythroid 2
chr4_+_24612205 0.67 ENSRNOT00000057382
EWS RNA-binding protein 1
chr14_-_84937725 0.67 ENSRNOT00000083839
ubiquinol-cytochrome c reductase, complex III subunit X
chr1_+_282134981 0.64 ENSRNOT00000036203
nanos C2HC-type zinc finger 1
chr2_-_232245319 0.57 ENSRNOT00000014510
hypothetical protein LOC691931
chrX_+_71155601 0.56 ENSRNOT00000076453
ENSRNOT00000048521
forkhead box O4
chr7_+_35472102 0.52 ENSRNOT00000010316
transmembrane and coiled-coil domain family 3
chr19_+_25969255 0.46 ENSRNOT00000004370
phenylalanyl-tRNA synthetase, alpha subunit
chr6_-_146195819 0.44 ENSRNOT00000007625
Sp4 transcription factor
chr4_-_152380184 0.39 ENSRNOT00000091473
ELKS/RAB6-interacting/CAST family member 1
chrX_+_69730242 0.37 ENSRNOT00000075980
ENSRNOT00000076425
ectodysplasin-A
chr8_-_116635851 0.35 ENSRNOT00000024939
RNA binding motif protein 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp148

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 30.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
5.7 17.2 GO:0072254 metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254)
5.3 15.9 GO:0018199 peptidyl-glutamine modification(GO:0018199)
5.3 31.7 GO:1900034 regulation of cellular response to heat(GO:1900034)
5.2 31.3 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048) positive regulation of high voltage-gated calcium channel activity(GO:1901843)
4.9 19.6 GO:0003350 pulmonary myocardium development(GO:0003350)
4.4 30.6 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
3.8 22.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
3.7 11.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
3.6 14.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
3.6 10.7 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
3.2 32.1 GO:0036376 sodium ion export from cell(GO:0036376)
3.0 12.1 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
3.0 8.9 GO:0051012 microtubule sliding(GO:0051012)
2.8 35.9 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
2.7 13.6 GO:0061144 alveolar secondary septum development(GO:0061144)
2.4 18.9 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
2.3 18.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
2.3 18.4 GO:0070842 aggresome assembly(GO:0070842)
2.2 11.2 GO:0001552 ovarian follicle atresia(GO:0001552)
2.1 24.7 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
2.0 22.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
2.0 20.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
1.8 5.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
1.7 5.2 GO:0038189 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) cardiac vascular smooth muscle cell development(GO:0060948) positive regulation of lymphangiogenesis(GO:1901492)
1.7 13.6 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
1.7 8.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
1.6 8.1 GO:0046098 guanine metabolic process(GO:0046098)
1.5 6.0 GO:0071883 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
1.4 11.2 GO:0072104 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
1.3 8.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
1.3 51.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
1.3 48.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
1.3 4.0 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
1.2 8.5 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
1.2 6.0 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
1.2 16.6 GO:1903830 magnesium ion transport(GO:0015693) magnesium ion transmembrane transport(GO:1903830)
1.2 9.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
1.2 8.1 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
1.2 3.5 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
1.1 6.7 GO:2001025 positive regulation of response to drug(GO:2001025)
1.1 3.3 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
1.0 5.8 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
1.0 1.9 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.9 4.4 GO:1905031 regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905031)
0.9 6.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.9 13.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.8 5.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.8 4.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.8 10.7 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.8 5.4 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.7 5.2 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.7 36.7 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.7 10.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.7 5.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.7 3.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.7 8.8 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.7 3.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.7 3.3 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.7 2.6 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.7 5.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.6 1.3 GO:1904350 regulation of protein catabolic process in the vacuole(GO:1904350)
0.6 1.9 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.6 43.5 GO:0048747 muscle fiber development(GO:0048747)
0.6 5.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.6 7.2 GO:0051764 actin crosslink formation(GO:0051764)
0.5 13.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.5 6.1 GO:0008343 adult feeding behavior(GO:0008343)
0.5 13.7 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.5 15.8 GO:0018345 protein palmitoylation(GO:0018345)
0.5 2.9 GO:0036016 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.5 1.9 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.5 2.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.5 3.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.4 3.0 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.4 1.1 GO:0030576 Cajal body organization(GO:0030576)
0.3 3.1 GO:0030953 astral microtubule organization(GO:0030953)
0.3 4.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 4.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.3 13.1 GO:0007628 adult walking behavior(GO:0007628)
0.3 7.6 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.3 3.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 3.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.3 13.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.2 3.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 13.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 5.8 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.2 9.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 1.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 0.6 GO:0098749 cerebellar neuron development(GO:0098749)
0.2 8.7 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.2 10.5 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.2 0.4 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 9.4 GO:0006497 protein lipidation(GO:0006497)
0.2 3.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.2 4.0 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.2 4.2 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 6.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 11.8 GO:1903955 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 5.5 GO:0033344 cholesterol efflux(GO:0033344)
0.1 4.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.6 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.1 7.7 GO:0046467 membrane lipid biosynthetic process(GO:0046467)
0.1 0.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 2.8 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 2.3 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 21.0 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.7 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.1 1.1 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 4.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.0 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 1.0 GO:0001662 behavioral fear response(GO:0001662)
0.0 4.2 GO:0007411 axon guidance(GO:0007411)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
10.2 30.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
5.7 22.7 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
5.3 32.1 GO:0044326 dendritic spine neck(GO:0044326)
5.1 20.6 GO:0045298 tubulin complex(GO:0045298)
2.6 31.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
2.2 11.2 GO:0005940 septin ring(GO:0005940)
2.0 6.0 GO:0098833 presynaptic endosome(GO:0098830) presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
1.8 5.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
1.3 26.2 GO:0043196 varicosity(GO:0043196)
1.2 22.4 GO:0097449 astrocyte projection(GO:0097449)
1.0 43.2 GO:0043034 costamere(GO:0043034)
0.7 3.0 GO:0031592 centrosomal corona(GO:0031592)
0.7 6.7 GO:1990635 proximal dendrite(GO:1990635)
0.7 8.0 GO:0016600 flotillin complex(GO:0016600)
0.5 4.0 GO:0044327 dendritic spine head(GO:0044327)
0.4 5.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 38.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.4 11.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 3.2 GO:0016589 NURF complex(GO:0016589)
0.4 30.6 GO:0031902 late endosome membrane(GO:0031902)
0.4 13.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.4 9.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.4 12.1 GO:0060170 ciliary membrane(GO:0060170)
0.4 37.3 GO:0031225 anchored component of membrane(GO:0031225)
0.3 7.3 GO:0070822 Sin3-type complex(GO:0070822)
0.3 3.1 GO:0042587 glycogen granule(GO:0042587)
0.3 9.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.3 4.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 6.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 73.1 GO:0014069 postsynaptic density(GO:0014069)
0.2 7.9 GO:0035869 ciliary transition zone(GO:0035869)
0.2 12.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 6.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.2 6.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 1.8 GO:0000439 core TFIIH complex(GO:0000439)
0.2 1.0 GO:0090543 Flemming body(GO:0090543)
0.2 2.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.2 11.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 5.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 4.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 15.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 0.5 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 11.6 GO:0032432 actin filament bundle(GO:0032432)
0.1 11.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 13.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 1.9 GO:0001741 XY body(GO:0001741)
0.1 4.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 8.1 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 5.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 14.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 9.6 GO:0043204 perikaryon(GO:0043204)
0.1 2.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 15.7 GO:0043235 receptor complex(GO:0043235)
0.1 5.9 GO:0043679 axon terminus(GO:0043679)
0.1 15.5 GO:0031965 nuclear membrane(GO:0031965)
0.1 5.2 GO:0005604 basement membrane(GO:0005604)
0.1 3.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.3 GO:0001772 immunological synapse(GO:0001772)
0.0 12.1 GO:0005925 focal adhesion(GO:0005925)
0.0 1.7 GO:0015030 Cajal body(GO:0015030)
0.0 6.7 GO:0005769 early endosome(GO:0005769)
0.0 4.9 GO:0001650 fibrillar center(GO:0001650)
0.0 9.0 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 30.2 GO:0005615 extracellular space(GO:0005615)
0.0 7.0 GO:0005911 cell-cell junction(GO:0005911)
0.0 15.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 21.6 GO:0005794 Golgi apparatus(GO:0005794)
0.0 4.3 GO:0005874 microtubule(GO:0005874)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 31.3 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
8.2 24.7 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
7.5 22.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
5.1 20.6 GO:0099609 microtubule lateral binding(GO:0099609)
5.1 30.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
3.4 48.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
2.8 8.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
2.4 30.6 GO:0098879 structural constituent of postsynaptic specialization(GO:0098879) structural constituent of postsynaptic density(GO:0098919)
2.3 32.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
2.3 13.6 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
2.1 10.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.0 6.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
1.8 23.8 GO:0030215 semaphorin receptor binding(GO:0030215)
1.7 17.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.7 13.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.7 6.8 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
1.7 5.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
1.7 11.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.6 37.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
1.5 6.0 GO:0010465 nerve growth factor receptor activity(GO:0010465) G-protein coupled neurotensin receptor activity(GO:0016492)
1.2 14.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
1.1 43.2 GO:0030506 ankyrin binding(GO:0030506)
1.1 11.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.1 16.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
1.0 7.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.9 19.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.8 4.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.8 34.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.7 9.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.7 4.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.7 20.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.7 6.0 GO:0098748 clathrin heavy chain binding(GO:0032050) clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.7 15.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.6 3.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.6 4.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.6 5.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.6 3.5 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.5 7.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.5 15.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5 13.4 GO:0019239 deaminase activity(GO:0019239)
0.5 15.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.5 38.7 GO:0005518 collagen binding(GO:0005518)
0.4 14.5 GO:0005501 retinoid binding(GO:0005501)
0.4 1.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 8.5 GO:0005112 Notch binding(GO:0005112)
0.3 42.8 GO:0001948 glycoprotein binding(GO:0001948)
0.3 9.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.3 4.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 12.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.3 12.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 12.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 6.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.2 59.3 GO:0008017 microtubule binding(GO:0008017)
0.2 6.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 20.7 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.2 18.3 GO:0051087 chaperone binding(GO:0051087)
0.2 1.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 4.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 3.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 10.2 GO:0005080 protein kinase C binding(GO:0005080)
0.2 5.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.2 5.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 1.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 8.2 GO:0042805 actinin binding(GO:0042805)
0.2 42.3 GO:0005096 GTPase activator activity(GO:0005096)
0.2 3.0 GO:0008009 chemokine activity(GO:0008009)
0.1 3.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 5.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 18.9 GO:0005179 hormone activity(GO:0005179)
0.1 3.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.1 7.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 1.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 2.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 2.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 1.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 6.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 2.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.3 GO:0016151 nickel cation binding(GO:0016151)
0.1 1.0 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0048018 receptor agonist activity(GO:0048018)
0.0 23.4 GO:0005509 calcium ion binding(GO:0005509)
0.0 2.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 7.4 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.3 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 3.7 GO:0005525 GTP binding(GO:0005525)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 20.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.5 30.5 PID S1P S1P1 PATHWAY S1P1 pathway
1.2 52.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.9 39.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.8 55.7 PID NOTCH PATHWAY Notch signaling pathway
0.4 5.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.4 66.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4 13.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.4 4.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.3 12.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 13.6 PID FGF PATHWAY FGF signaling pathway
0.3 9.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 78.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.2 2.9 PID IL3 PATHWAY IL3-mediated signaling events
0.2 3.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 4.0 ST GA12 PATHWAY G alpha 12 Pathway
0.2 15.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.2 1.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 11.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 14.8 PID CMYB PATHWAY C-MYB transcription factor network
0.2 5.8 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 3.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 3.1 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 43.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
2.4 36.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
2.0 8.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
1.6 19.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.3 13.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
1.0 17.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.0 13.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
1.0 51.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
1.0 22.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.9 45.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.7 20.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.6 9.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.6 24.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.4 5.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.4 9.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.4 10.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 4.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 14.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.3 5.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3 5.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 3.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 5.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 4.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.2 16.9 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.2 7.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 5.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.2 4.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 3.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.2 1.9 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 3.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 6.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 11.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 2.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 5.8 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 2.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 4.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling