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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfp128

Z-value: 0.41

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Transcription factors associated with Zfp128

Gene Symbol Gene ID Gene Info
ENSRNOG00000031113 zinc finger protein 128
ENSRNOG00000031459 zinc finger protein 128

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp128rn6_v1_chr1_-_65701867_65701867-0.181.1e-03Click!

Activity profile of Zfp128 motif

Sorted Z-values of Zfp128 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_23256158 13.20 ENSRNOT00000015336
betaine-homocysteine S-methyltransferase
chr10_+_11240138 9.29 ENSRNOT00000048687
sarcalumenin
chr13_+_75111778 8.88 ENSRNOT00000006924
tumor protein p53 inducible protein 3
chr6_-_23316962 8.48 ENSRNOT00000065421
CAP-GLY domain containing linker protein family, member 4
chr5_-_78985990 8.31 ENSRNOT00000009248
alpha-1-microglobulin/bikunin precursor
chr8_-_130550388 8.12 ENSRNOT00000026355
cytochrome P450, family 8, subfamily b, polypeptide 1
chr1_+_101427195 6.93 ENSRNOT00000028271
glycogen synthase 1
chrX_+_156999826 6.11 ENSRNOT00000081819
isocitrate dehydrogenase 3 (NAD), gamma
chr10_+_102136283 5.97 ENSRNOT00000003735
somatostatin receptor 2
chr5_+_151692108 4.82 ENSRNOT00000086144
family with sequence similarity 46, member B
chr1_-_170471076 3.81 ENSRNOT00000025159
ADP-ribosylation factor interacting protein 2
chr2_+_210685197 3.75 ENSRNOT00000072342
glutathione S-transferase mu 3
chr1_+_170471238 3.68 ENSRNOT00000076961
ENSRNOT00000075597
ENSRNOT00000076631
ENSRNOT00000076783
translocase of inner mitochondrial membrane 10B
dynein heavy chain domain 1
chr8_-_59629133 3.14 ENSRNOT00000019458
cholinergic receptor nicotinic beta 4 subunit
chr6_-_128989812 3.03 ENSRNOT00000085943
ankyrin repeat and SOCS box protein 2-like
chr2_-_210839295 2.80 ENSRNOT00000025994
glutathione S-transferase mu 4
chr8_-_62215293 2.38 ENSRNOT00000080448
phosphopantothenoylcysteine decarboxylase
chr10_+_110631494 2.29 ENSRNOT00000054915
fructosamine 3 kinase
chr5_-_57168610 2.00 ENSRNOT00000090499
beta-1,4-galactosyltransferase 1
chr8_+_111107358 1.88 ENSRNOT00000011203
anaphase promoting complex subunit 13
chr20_+_32717564 1.55 ENSRNOT00000030642
regulatory factor X, 6
chr14_+_2892753 1.44 ENSRNOT00000061630
ecotropic viral integration site 5
chr5_-_147867583 1.38 ENSRNOT00000000139
karyopherin subunit alpha 6
chr4_-_150616895 1.19 ENSRNOT00000073562
ankyrin repeat domain 26
chr3_-_177089199 0.98 ENSRNOT00000020873
zinc finger protein 512B
chr7_+_117390285 0.95 ENSRNOT00000016464
exosome component 4
chr1_-_102970950 0.92 ENSRNOT00000018194
tumor susceptibility 101
chr8_-_21384131 0.83 ENSRNOT00000071010
zinc finger protein 560
chr8_-_64154396 0.76 ENSRNOT00000031262
Bardet-Biedl syndrome 4
chr7_-_19088972 0.74 ENSRNOT00000049266
vomeronasal 2 receptor, 57
chr10_-_71383378 0.70 ENSRNOT00000077025
dual specificity phosphatase 14
chr12_-_51341663 0.66 ENSRNOT00000066892
ENSRNOT00000052202
phosphatidylinositol transfer protein, beta
chr18_+_41022552 0.65 ENSRNOT00000005260
COMM domain containing 10
chr1_+_162320730 0.64 ENSRNOT00000035743
potassium channel tetramerization domain containing 21
chr1_-_170186462 0.61 ENSRNOT00000035798
olfactory receptor 202
chr10_-_71383602 0.55 ENSRNOT00000083300
dual specificity phosphatase 14
chr20_-_31598118 0.52 ENSRNOT00000046537
collagen type XIII alpha 1 chain
chr6_+_18877907 0.50 ENSRNOT00000084222
alkB homolog 8, tRNA methyltransferase
chr20_-_13581164 0.45 ENSRNOT00000033298
zinc finger protein 280B
chr7_-_22943159 0.40 ENSRNOT00000047547
vomeronasal 2 receptor, 57
chr3_-_8690305 0.39 ENSRNOT00000035002
zyg-11 related, cell cycle regulator
chr4_+_155532109 0.37 ENSRNOT00000077245
Nanog homeobox
chr4_+_155531906 0.31 ENSRNOT00000060937
Nanog homeobox
chr5_+_103251986 0.30 ENSRNOT00000008757
centlein
chr1_-_167971151 0.30 ENSRNOT00000043023
olfactory receptor 53
chrX_+_73475049 0.28 ENSRNOT00000050601
zinc finger protein 36, C3H type-like 3
chrX_-_156999650 0.22 ENSRNOT00000083557
signal sequence receptor subunit 4
chr1_-_174350196 0.15 ENSRNOT00000055158
similar to predicted gene ICRFP703B1614Q5.5
chr8_+_23014956 0.13 ENSRNOT00000018009
protein kinase C substrate 80K-H
chr4_+_99398494 0.05 ENSRNOT00000064374
ring finger protein 103
chr8_+_13305152 0.03 ENSRNOT00000012940
MRE11 homolog A, double strand break repair nuclease
chr11_-_45124423 0.03 ENSRNOT00000046383
filamin A interacting protein 1-like
chrX_-_57058526 0.01 ENSRNOT00000091191

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp128

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.2 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
2.3 9.3 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
1.0 3.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
1.0 6.1 GO:0006102 isocitrate metabolic process(GO:0006102)
1.0 6.0 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.9 2.8 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.8 8.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.5 2.0 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.3 0.9 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 3.8 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 0.8 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.2 8.9 GO:0006739 NADP metabolic process(GO:0006739)
0.2 1.0 GO:0071051 U4 snRNA 3'-end processing(GO:0034475) DNA deamination(GO:0045006) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2 1.5 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 6.9 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.7 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 1.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 2.3 GO:0006040 amino sugar metabolic process(GO:0006040)
0.0 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 1.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 1.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 3.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0045242 mitochondrial isocitrate dehydrogenase complex (NAD+)(GO:0005962) isocitrate dehydrogenase complex (NAD+)(GO:0045242)
0.7 3.7 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 2.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 3.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 3.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.8 GO:0034464 BBSome(GO:0034464)
0.1 6.9 GO:0016234 inclusion body(GO:0016234)
0.1 8.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 8.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.3 GO:0019862 IgA binding(GO:0019862)
1.7 13.2 GO:0008172 S-methyltransferase activity(GO:0008172)
1.5 6.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.5 8.9 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.0 6.0 GO:0004994 somatostatin receptor activity(GO:0004994)
1.0 6.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.7 2.0 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.3 8.1 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.2 3.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 2.8 GO:0043295 glutathione binding(GO:0043295)
0.1 0.7 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 3.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.9 GO:0046790 virion binding(GO:0046790)
0.1 0.8 GO:0034452 dynactin binding(GO:0034452)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 3.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 9.3 GO:0005525 GTP binding(GO:0005525)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 3.8 PID ARF 3PATHWAY Arf1 pathway
0.1 8.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 8.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5 13.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.3 6.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 3.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.9 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 6.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 1.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 6.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.1 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.7 REACTOME PI METABOLISM Genes involved in PI Metabolism