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GSE53960: rat RNA-Seq transcriptomic Bodymap
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Results for Zfp105
Z-value: 0.59
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Transcription factors associated with Zfp105
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zfp105 | rn6_v1_chr8_+_131998778_131998778 | -0.06 | 2.9e-01 | Click! |
Top targets:  
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_177196180 Show fit | 25.84 |
ENSRNOT00000018999
|
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
|
| chr9_+_2202511 Show fit | 15.92 |
ENSRNOT00000017556
|
SATB homeobox 1 |
|
| chr15_-_24199341 Show fit | 12.55 |
ENSRNOT00000015553
|
DLG associated protein 5 |
|
| chr5_-_160405050 Show fit | 12.00 |
ENSRNOT00000081899
|
chymotrypsin C |
|
| chr11_-_82366505 Show fit | 8.19 |
ENSRNOT00000041326
|
similar to ribosomal protein L27a |
|
| chr5_+_161889342 Show fit | 8.06 |
ENSRNOT00000040481
|
ribosomal protein S20-like |
|
| chr17_+_78876111 Show fit | 7.69 |
ENSRNOT00000057895
|
ribosomal protein L34, pseudogene 1 |
|
| chr9_-_1012450 Show fit | 7.52 |
ENSRNOT00000051449
|
ribosomal protein S20-like |
|
| chr10_-_57275708 Show fit | 7.40 |
ENSRNOT00000005370
|
profilin 1 |
|
| chr7_-_23953002 Show fit | 7.32 |
ENSRNOT00000047587
|
similar to 40S ribosomal protein S20 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Zfp105
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 28.3 | GO:0006412 | translation(GO:0006412) |
| 1.2 | 25.8 | GO:0097503 | sialylation(GO:0097503) |
| 1.1 | 15.9 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.0 | 12.6 | GO:0006470 | protein dephosphorylation(GO:0006470) |
| 0.7 | 7.4 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.7 | 5.3 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.1 | 5.2 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.2 | 4.4 | GO:0035067 | negative regulation of histone acetylation(GO:0035067) |
| 0.1 | 4.4 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.9 | 3.8 | GO:2000814 | positive regulation of barbed-end actin filament capping(GO:2000814) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 25.8 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.3 | 15.9 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.9 | 12.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 10.5 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 7.4 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.2 | 4.4 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 4.4 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 4.4 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.6 | 3.8 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.0 | 3.5 | GO:0045095 | keratin filament(GO:0045095) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 43.2 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 1.1 | 25.8 | GO:0008373 | sialyltransferase activity(GO:0008373) |
| 0.1 | 12.6 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
| 0.1 | 12.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 9.2 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.7 | 7.4 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 4.4 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 3.9 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.6 | 3.8 | GO:0035650 | AP-1 adaptor complex binding(GO:0035650) |
| 0.0 | 3.5 | GO:0030246 | carbohydrate binding(GO:0030246) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 15.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.3 | 12.6 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.2 | 12.0 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.2 | 7.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 4.4 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 3.8 | PID RAC1 PATHWAY | RAC1 signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 15.9 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 10.5 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 7.4 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 4.4 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.1 | 1.7 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |