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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfp105

Z-value: 0.59

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Transcription factors associated with Zfp105

Gene Symbol Gene ID Gene Info
Zfp105
ENSRNOG00000032919 zinc finger protein 105

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfp105rn6_v1_chr8_+_131998778_131998778-0.062.9e-01Click!

Activity profile of Zfp105 motif

Sorted Z-values of Zfp105 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_177196180 25.84 ENSRNOT00000018999
St8sia1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr9_+_2202511 15.92 ENSRNOT00000017556
Satb1
SATB homeobox 1
chr15_-_24199341 12.55 ENSRNOT00000015553
Dlgap5
DLG associated protein 5
chr5_-_160405050 12.00 ENSRNOT00000081899
Ctrc
chymotrypsin C
chr11_-_82366505 8.19 ENSRNOT00000041326
RGD1559972
similar to ribosomal protein L27a
chr5_+_161889342 8.06 ENSRNOT00000040481
LOC100362684
ribosomal protein S20-like
chr17_+_78876111 7.69 ENSRNOT00000057895
Rpl34-ps1
ribosomal protein L34, pseudogene 1
chr9_-_1012450 7.52 ENSRNOT00000051449
LOC100359951
ribosomal protein S20-like
chr10_-_57275708 7.40 ENSRNOT00000005370
Pfn1
profilin 1
chr7_-_23953002 7.32 ENSRNOT00000047587
RGD1563124
similar to 40S ribosomal protein S20
chr3_+_22964230 6.94 ENSRNOT00000041813
LOC100362149
ribosomal protein S20-like
chr13_+_91334004 5.73 ENSRNOT00000041384
LOC108352650
40S ribosomal protein S29
chr1_-_31528083 5.65 ENSRNOT00000061041
Rpl26-ps2
ribosomal protein L26, pseudogene 2
chr20_+_8486265 5.32 ENSRNOT00000072213
LOC100909911
40S ribosomal protein S20-like
chr2_-_199479309 5.30 ENSRNOT00000042661
Rpl38
ribosomal protein L38
chr1_-_219395623 5.24 ENSRNOT00000040261
Rpl35a
ribosomal protein L35a
chr7_-_2961873 4.90 ENSRNOT00000067441
Rps15-ps2
ribosomal protein S15, pseudogene 2
chrX_+_74824504 4.59 ENSRNOT00000048963
LOC680353
similar to 60S ribosomal protein L38
chr6_-_103605256 4.44 ENSRNOT00000006005
Dcaf5
DDB1 and CUL4 associated factor 5
chrX_-_115496045 4.43 ENSRNOT00000051134
LOC100361854
ribosomal protein S26-like
chr8_+_67295727 4.43 ENSRNOT00000020443
Anp32a
acidic nuclear phosphoprotein 32 family member A
chr15_+_28439317 4.39 ENSRNOT00000060519
LOC690384
similar to ribosomal protein L31
chr3_+_98695503 4.12 ENSRNOT00000042764
AABR07053304.1

chr9_+_81535483 3.77 ENSRNOT00000077285
Arpc2
actin related protein 2/3 complex, subunit 2
chr4_-_162680757 3.55 ENSRNOT00000085918
Klra5
killer cell lectin-like receptor, subfamily A, member 5
chr7_-_143167772 3.49 ENSRNOT00000011374
Krt85
keratin 85
chr7_-_80457816 3.43 ENSRNOT00000039430
AABR07057617.1

chr8_+_39164916 3.42 ENSRNOT00000011309
Acrv1
acrosomal vesicle protein 1
chrX_-_157200981 3.41 ENSRNOT00000087364
AABR07071935.1

chr10_+_87846947 2.74 ENSRNOT00000077436
Krtap9-5
keratin associated protein 9-5
chr1_-_246110218 2.46 ENSRNOT00000077544
Rfx3
regulatory factor X3
chr10_-_61088827 2.24 ENSRNOT00000047421
Olr1517
olfactory receptor 1517
chr9_+_61552374 2.18 ENSRNOT00000050090
Tmem258b
transmembrane protein 258 B
chr15_-_93765498 1.98 ENSRNOT00000093297
Mycbp2
MYC binding protein 2, E3 ubiquitin protein ligase
chr7_+_144503534 1.73 ENSRNOT00000021543
Tbca
tubulin folding cofactor A
chr10_+_92769031 1.66 ENSRNOT00000090759
AABR07030543.1

chr1_-_209641123 1.45 ENSRNOT00000021702
Ebf3
early B-cell factor 3
chr1_-_149441437 0.98 ENSRNOT00000041780
Vom2r41
vomeronasal 2 receptor, 41
chr3_-_78112770 0.11 ENSRNOT00000008396
Olr694
olfactory receptor 694
chr13_-_104156454 0.11 ENSRNOT00000031419
AABR07022046.1

chr3_-_74631883 0.08 ENSRNOT00000013215
Olr539
olfactory receptor 539

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp105

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 25.8 GO:0097503 sialylation(GO:0097503)
1.1 15.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.9 3.8 GO:2000814 positive regulation of barbed-end actin filament capping(GO:2000814)
0.8 2.5 GO:0002071 glandular epithelial cell maturation(GO:0002071) positive regulation of type B pancreatic cell development(GO:2000078)
0.7 7.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.7 5.3 GO:0048318 axial mesoderm development(GO:0048318)
0.2 1.7 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 4.4 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.2 2.0 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 4.4 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 5.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 3.5 GO:0030101 natural killer cell activation(GO:0030101)
0.0 28.3 GO:0006412 translation(GO:0006412)
0.0 12.6 GO:0006470 protein dephosphorylation(GO:0006470)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.6 3.8 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.5 25.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.3 15.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.2 4.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 10.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 4.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 7.4 GO:0072562 blood microparticle(GO:0072562)
0.0 3.5 GO:0045095 keratin filament(GO:0045095)
0.0 4.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 3.4 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 25.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.7 7.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.6 3.8 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.2 43.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 12.6 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 12.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 9.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 4.4 GO:0005178 integrin binding(GO:0005178)
0.0 3.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 3.5 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.6 PID AURORA A PATHWAY Aurora A signaling
0.2 15.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 12.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 7.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 4.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 15.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 7.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 10.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 4.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements