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GSE53960: rat RNA-Seq transcriptomic Bodymap

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Results for Zfhx3

Z-value: 1.04

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Transcription factors associated with Zfhx3

Gene Symbol Gene ID Gene Info
Zfhx3
ENSRNOG00000014452 zinc finger homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfhx3rn6_v1_chr19_-_42920344_429203440.394.9e-13Click!

Activity profile of Zfhx3 motif

Sorted Z-values of Zfhx3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_14229067 57.91 ENSRNOT00000025534
ENSRNOT00000092865
C5
complement C5
chr13_+_56598957 55.95 ENSRNOT00000016944
ENSRNOT00000080335
ENSRNOT00000089913
F13b
coagulation factor XIII B chain
chr6_+_80188943 55.66 ENSRNOT00000059335
Mia2
melanoma inhibitory activity 2
chr6_+_127743971 50.30 ENSRNOT00000013045
Serpina4
serpin family A member 4
chr17_-_43543172 47.48 ENSRNOT00000080684
ENSRNOT00000029626
ENSRNOT00000082719
Slc17a3
solute carrier family 17 member 3
chr5_+_117698764 43.58 ENSRNOT00000011486
Angptl3
angiopoietin-like 3
chr10_+_89285855 37.74 ENSRNOT00000028033
G6pc
glucose-6-phosphatase, catalytic subunit
chr20_+_30690810 37.64 ENSRNOT00000000687
Pcbd1
pterin-4 alpha-carbinolamine dehydratase 1
chr1_+_88955440 36.05 ENSRNOT00000091101
Prodh2
proline dehydrogenase 2
chr14_-_19132208 36.04 ENSRNOT00000060535
Afm
afamin
chr1_+_88955135 34.45 ENSRNOT00000083550
Prodh2
proline dehydrogenase 2
chr10_+_89286047 34.18 ENSRNOT00000085831
G6pc
glucose-6-phosphatase, catalytic subunit
chr1_+_107262659 32.88 ENSRNOT00000022499
Gas2
growth arrest-specific 2
chr8_-_77398156 31.60 ENSRNOT00000091858
ENSRNOT00000085349
ENSRNOT00000082763
Lipc
lipase C, hepatic type
chr1_-_48563776 31.07 ENSRNOT00000023368
Plg
plasminogen
chr2_-_88763733 30.72 ENSRNOT00000059424
LOC688389
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr3_+_117422704 28.49 ENSRNOT00000085647
Slc12a1
solute carrier family 12 member 1
chr9_+_95256627 26.60 ENSRNOT00000025291
Ugt1a5
UDP glucuronosyltransferase family 1 member A5
chr4_-_176294997 25.64 ENSRNOT00000015112
ENSRNOT00000051461
ENSRNOT00000000026
ENSRNOT00000039877
ENSRNOT00000049303
Slc21a4
kidney specific organic anion transporter
chr12_-_29743705 25.52 ENSRNOT00000001185
Caln1
calneuron 1
chr14_-_80973456 25.43 ENSRNOT00000013257
Hgfac
HGF activator
chr2_+_235264219 25.28 ENSRNOT00000086245
Cfi
complement factor I
chr10_-_103848035 23.71 ENSRNOT00000029001
Fads6
fatty acid desaturase 6
chr2_-_243407608 23.54 ENSRNOT00000014631
Mttp
microsomal triglyceride transfer protein
chr13_+_91080341 23.05 ENSRNOT00000000058
Crp
C-reactive protein
chr1_+_261291870 21.93 ENSRNOT00000049914
Hoga1
4-hydroxy-2-oxoglutarate aldolase 1
chr16_+_7758996 19.55 ENSRNOT00000061063
Btd
biotinidase
chr1_-_126211439 17.69 ENSRNOT00000014988
Tjp1
tight junction protein 1
chr2_-_88660449 13.20 ENSRNOT00000051741
Slc7a12
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr2_-_166682325 13.11 ENSRNOT00000091198
ENSRNOT00000012422
Sptssb
serine palmitoyltransferase, small subunit B
chr1_-_266428239 12.71 ENSRNOT00000027160
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
chr13_-_86671515 12.20 ENSRNOT00000082869
AABR07021704.1

chr5_+_8916633 11.55 ENSRNOT00000066395
Ppp1r42
protein phosphatase 1, regulatory subunit 42
chr13_+_99369126 11.38 ENSRNOT00000072695
LOC498300
similar to degenerative spermatocyte homolog
chr2_-_88553086 10.86 ENSRNOT00000042494
LOC361914
similar to solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr20_+_6869767 10.44 ENSRNOT00000000631
ENSRNOT00000086330
ENSRNOT00000093188
ENSRNOT00000093736
RGD735065
similar to GI:13385412-like protein splice form I
chr16_-_10802512 8.54 ENSRNOT00000079554
Bmpr1a
bone morphogenetic protein receptor type 1A
chr8_+_33239139 8.49 ENSRNOT00000011589
Arhgap32
Rho GTPase activating protein 32
chr14_+_18983853 8.41 ENSRNOT00000003836
Rassf6
Ras association domain family member 6
chr17_-_79085076 8.01 ENSRNOT00000057851
Fam171a1
family with sequence similarity 171, member A1
chr5_+_6373583 7.82 ENSRNOT00000084749
AABR07046778.1

chr17_-_78499881 7.47 ENSRNOT00000079260
Fam107b
family with sequence similarity 107, member B
chr14_-_103321270 7.43 ENSRNOT00000006157
Meis1
Meis homeobox 1
chr13_+_42008842 7.36 ENSRNOT00000038811
Gpr39
G protein-coupled receptor 39
chrM_+_9870 7.22 ENSRNOT00000044582
Mt-nd4l
mitochondrially encoded NADH 4L dehydrogenase
chr6_-_125723732 6.79 ENSRNOT00000084815
Fbln5
fibulin 5
chr9_+_77320726 6.17 ENSRNOT00000068450
Spag16
sperm associated antigen 16
chr19_-_38484611 5.82 ENSRNOT00000077960
Nfat5
nuclear factor of activated T-cells 5
chr11_+_65743892 5.41 ENSRNOT00000085226
AC106292.2

chr6_-_71199110 5.38 ENSRNOT00000081883
Prkd1
protein kinase D1
chrX_+_83597265 4.57 ENSRNOT00000066667
LOC100911639
uncharacterized LOC100911639
chr3_-_74868575 4.47 ENSRNOT00000051625
Olr544
olfactory receptor 544
chr2_-_27287605 4.43 ENSRNOT00000034041
Ankdd1b
ankyrin repeat and death domain containing 1B
chr4_-_167068838 4.34 ENSRNOT00000029713
Tas2r125
taste receptor, type 2, member 125
chr14_-_42560174 4.23 ENSRNOT00000003128
Tmem33
transmembrane protein 33
chr13_+_98231326 4.00 ENSRNOT00000003837
Cdc42bpa
CDC42 binding protein kinase alpha
chrM_-_14061 3.95 ENSRNOT00000051268
Mt-nd6
mitochondrially encoded NADH dehydrogenase 6
chr2_+_55747318 3.76 ENSRNOT00000050655
Dab2
DAB2, clathrin adaptor protein
chrX_+_83678339 3.59 ENSRNOT00000005997
Apool
apolipoprotein O-like
chr5_+_116420690 3.41 ENSRNOT00000087089
Nfia
nuclear factor I/A
chr18_-_28017925 3.24 ENSRNOT00000075420
Lrrtm2
leucine rich repeat transmembrane neuronal 2
chr8_-_53277859 3.11 ENSRNOT00000009574
Htr3b
5-hydroxytryptamine receptor 3B
chr13_-_98023829 2.92 ENSRNOT00000075426
Kif28p
kinesin family member 28, pseudogene
chr16_+_8211420 2.89 ENSRNOT00000079609
Oxnad1
oxidoreductase NAD-binding domain containing 1
chr9_-_63291350 2.41 ENSRNOT00000058831
Hsfy2
heat shock transcription factor, Y linked 2
chr19_-_56983807 2.16 ENSRNOT00000043529
Cox6c-ps1
cytochrome c oxidase subunit VIc, pseudogene
chr3_-_77883067 2.15 ENSRNOT00000087979
Olr677
olfactory receptor 677
chrM_+_2740 2.12 ENSRNOT00000047550
Mt-nd1
mitochondrially encoded NADH dehydrogenase 1
chrX_+_152999016 1.90 ENSRNOT00000088234
Zfp185
zinc finger protein 185
chr3_-_77389521 1.87 ENSRNOT00000043928
Olr657
olfactory receptor 657
chr3_-_77792014 1.78 ENSRNOT00000091085
Olr671
olfactory receptor 671
chr1_-_813517 1.71 ENSRNOT00000041332
Vom2r5
vomeronasal 2 receptor, 5
chr1_-_173456488 1.63 ENSRNOT00000044753
Olr282
olfactory receptor 282
chr10_+_87832743 1.61 ENSRNOT00000055286
Krtap31-1
keratin associated protein 31-1
chr11_+_43194348 1.56 ENSRNOT00000075303
Olr1532
olfactory receptor 1532
chr2_+_115074344 1.55 ENSRNOT00000073657
LOC100910500
olfactory receptor 144-like
chr1_-_134871167 1.48 ENSRNOT00000076300
Chd2
chromodomain helicase DNA binding protein 2
chr1_-_205030567 1.46 ENSRNOT00000023404
Ctbp2
C-terminal binding protein 2
chrM_+_14136 1.38 ENSRNOT00000042098
Mt-cyb
mitochondrially encoded cytochrome b
chr4_-_165774126 1.26 ENSRNOT00000007453
Tas2r107
taste receptor, type 2, member 107
chr8_-_126390801 1.05 ENSRNOT00000089732
AABR07071661.1

chr3_+_104816987 1.04 ENSRNOT00000042103
ENSRNOT00000044625
Fmn1
formin 1
chr3_+_102859815 0.87 ENSRNOT00000037906
Olr771
olfactory receptor 771
chr6_-_146861787 0.78 ENSRNOT00000074197
Abcb5
ATP binding cassette subfamily B member 5
chr7_-_144837395 0.70 ENSRNOT00000089024
Cbx5
chromobox 5
chr11_-_45616429 0.67 ENSRNOT00000046587
Olr1533
olfactory receptor 1533
chr2_-_242828629 0.48 ENSRNOT00000043369
LOC499715
LRRGT00095
chr1_-_149787308 0.44 ENSRNOT00000088514
LOC100909966
olfactory receptor 6F1-like
chr11_-_768644 0.40 ENSRNOT00000090197
Epha3
Eph receptor A3
chr6_-_86223052 0.22 ENSRNOT00000046828
Fscb
fibrous sheath CABYR binding protein
chr20_+_37587687 0.21 ENSRNOT00000001050
Msl3l2
male-specific lethal 3-like 2 (Drosophila)
chr11_-_13999862 0.08 ENSRNOT00000045835
Lipi
lipase I
chrX_-_35777243 0.03 ENSRNOT00000040912
Rs1
retinoschisin 1
chr1_-_252167752 0.03 ENSRNOT00000074115
LOC100360690
tear acid-lipase-like protein-like

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfhx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
23.5 70.5 GO:0010133 proline catabolic process to glutamate(GO:0010133)
14.8 44.3 GO:0010034 response to acetate(GO:0010034)
10.4 31.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
9.7 57.9 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
9.5 28.5 GO:0032978 protein insertion into membrane from inner side(GO:0032978)
9.3 55.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
8.7 43.6 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
7.2 71.9 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
6.4 25.6 GO:0051958 methotrexate transport(GO:0051958)
5.5 21.9 GO:0009436 glyoxylate catabolic process(GO:0009436)
4.7 37.6 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
4.3 47.5 GO:0015747 urate transport(GO:0015747)
3.8 23.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
3.3 13.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
3.0 26.6 GO:0052697 xenobiotic glucuronidation(GO:0052697)
2.9 23.5 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
2.8 8.5 GO:0048377 lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378) regulation of cardiac ventricle development(GO:1904412)
2.5 7.4 GO:0035483 gastric emptying(GO:0035483)
2.2 17.7 GO:0071000 response to magnetism(GO:0071000)
2.1 6.2 GO:0051012 microtubule sliding(GO:0051012)
1.6 15.8 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
1.3 3.8 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
1.2 47.3 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
1.1 4.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.9 36.0 GO:0051180 vitamin transport(GO:0051180)
0.9 25.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.8 6.8 GO:2000121 regulation of removal of superoxide radicals(GO:2000121)
0.6 19.5 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.4 3.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.3 7.4 GO:0035855 megakaryocyte development(GO:0035855)
0.3 4.0 GO:0007097 nuclear migration(GO:0007097)
0.3 55.9 GO:0007596 blood coagulation(GO:0007596)
0.3 1.0 GO:0072092 ureteric bud invasion(GO:0072092)
0.3 0.8 GO:0048749 compound eye development(GO:0048749)
0.3 3.6 GO:0042407 cristae formation(GO:0042407)
0.2 1.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 5.8 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.2 3.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.2 3.4 GO:0072189 ureter development(GO:0072189)
0.2 1.4 GO:0033590 response to cobalamin(GO:0033590)
0.2 50.3 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.4 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 7.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 2.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.1 1.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 11.6 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.1 7.5 GO:0007605 sensory perception of sound(GO:0007605)
0.1 4.0 GO:0042220 response to cocaine(GO:0042220)
0.0 3.7 GO:0050909 sensory perception of taste(GO:0050909)
0.0 2.9 GO:0072384 organelle transport along microtubule(GO:0072384)
0.0 2.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
10.4 31.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
8.3 57.9 GO:0005579 membrane attack complex(GO:0005579)
2.8 55.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.6 13.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.4 17.7 GO:0046581 intercellular canaliculus(GO:0046581)
1.4 6.8 GO:0071953 elastic fiber(GO:0071953)
1.2 6.2 GO:1990716 axonemal central apparatus(GO:1990716)
1.1 31.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
1.1 11.6 GO:0002177 manchette(GO:0002177)
0.9 3.8 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.9 25.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.9 23.2 GO:0031528 microvillus membrane(GO:0031528)
0.8 4.0 GO:0070469 respiratory chain(GO:0070469)
0.6 76.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.5 3.6 GO:0061617 MICOS complex(GO:0061617)
0.3 36.0 GO:0072562 blood microparticle(GO:0072562)
0.2 5.4 GO:0000421 autophagosome membrane(GO:0000421)
0.2 82.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 14.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 157.2 GO:0005615 extracellular space(GO:0005615)
0.1 8.5 GO:0005901 caveola(GO:0005901)
0.1 1.5 GO:0097470 ribbon synapse(GO:0097470)
0.1 10.4 GO:0030496 midbody(GO:0030496)
0.1 8.5 GO:0001650 fibrillar center(GO:0001650)
0.1 66.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 2.9 GO:0005871 kinesin complex(GO:0005871)
0.1 0.7 GO:0010369 chromocenter(GO:0010369)
0.0 1.6 GO:0045095 keratin filament(GO:0045095)
0.0 3.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 6.9 GO:0009986 cell surface(GO:0009986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
23.5 70.5 GO:0004657 proline dehydrogenase activity(GO:0004657)
19.3 57.9 GO:0031714 C5a anaphylatoxin chemotactic receptor binding(GO:0031714)
14.4 71.9 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
12.5 37.6 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
9.5 28.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
9.3 55.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
6.5 19.5 GO:0047708 biotinidase activity(GO:0047708)
6.4 25.6 GO:0015350 methotrexate transporter activity(GO:0015350)
5.5 21.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
5.3 31.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
4.8 43.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
4.8 48.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
3.3 23.0 GO:0001849 complement component C1q binding(GO:0001849)
2.7 54.6 GO:0034185 apolipoprotein binding(GO:0034185)
2.6 13.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
2.2 17.7 GO:0071253 connexin binding(GO:0071253)
1.4 8.5 GO:0098821 BMP receptor activity(GO:0098821)
0.9 12.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.9 26.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.6 47.3 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.5 25.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.5 12.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.4 50.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 11.6 GO:0070840 dynein complex binding(GO:0070840)
0.4 35.8 GO:0019842 vitamin binding(GO:0019842)
0.4 3.8 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 5.4 GO:0004697 protein kinase C activity(GO:0004697)
0.2 3.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 4.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 1.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 25.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 25.5 GO:0008017 microtubule binding(GO:0008017)
0.1 3.1 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.1 1.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 2.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 1.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 6.7 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 2.4 GO:0005178 integrin binding(GO:0005178)
0.0 4.0 GO:0000287 magnesium ion binding(GO:0000287)
0.0 4.8 GO:0005549 odorant binding(GO:0005549)
0.0 1.5 GO:0004386 helicase activity(GO:0004386)
0.0 15.3 GO:0004930 G-protein coupled receptor activity(GO:0004930)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 50.3 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
1.3 71.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.8 31.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.6 43.6 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.5 32.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.5 23.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.5 17.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.4 5.4 PID IGF1 PATHWAY IGF1 pathway
0.2 5.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 51.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 8.5 PID BMP PATHWAY BMP receptor signaling
0.1 8.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 3.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 3.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.0 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 17.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 6.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 55.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
3.2 55.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
3.1 106.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
1.6 31.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.5 71.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
1.4 26.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.3 17.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
1.2 32.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.1 12.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 3.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 8.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 24.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 37.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 5.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 3.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 7.3 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport