Project

GSE53960: rat RNA-Seq transcriptomic Bodymap

Navigation
Downloads

Results for Zbtb7b

Z-value: 0.76

Motif logo

Transcription factors associated with Zbtb7b

Gene Symbol Gene ID Gene Info
ENSRNOG00000020640 zinc finger and BTB domain containing 7B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb7brn6_v1_chr2_-_188718704_1887187040.159.0e-03Click!

Activity profile of Zbtb7b motif

Sorted Z-values of Zbtb7b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_255376833 25.88 ENSRNOT00000024941
protein phosphatase 1, regulatory subunit 3C
chr18_-_15540177 20.91 ENSRNOT00000022113
transthyretin
chr15_-_28313841 19.57 ENSRNOT00000085897
NDRG family member 2
chr1_-_215834704 19.57 ENSRNOT00000073850
insulin-like growth factor 2
chr10_+_39655455 18.64 ENSRNOT00000058817
acyl-CoA synthetase long-chain family member 6
chr4_-_4473307 17.47 ENSRNOT00000045773
dipeptidyl peptidase like 6
chr15_+_33600102 17.12 ENSRNOT00000022664
CKLF-like MARVEL transmembrane domain containing 5
chr17_-_69827112 15.58 ENSRNOT00000023835
aldo-keto reductase family 1, member C14
chr3_+_92640752 15.20 ENSRNOT00000007604
solute carrier family 1 member 2
chr10_+_86657285 14.98 ENSRNOT00000087346
thyroid hormone receptor alpha
chrX_-_142248369 14.59 ENSRNOT00000091330
fibroblast growth factor 13
chr14_-_92117923 14.25 ENSRNOT00000044726
growth factor receptor bound protein 10
chr2_-_179704629 13.96 ENSRNOT00000083361
ENSRNOT00000077941
glutamate ionotropic receptor AMPA type subunit 2
chr8_-_98738446 13.59 ENSRNOT00000019860
Zic family member 1
chr17_+_12762752 13.28 ENSRNOT00000044842
DIRAS family GTPase 2
chrX_+_110016995 13.14 ENSRNOT00000093542
Nik related kinase
chr1_-_80599572 13.02 ENSRNOT00000024832
apolipoprotein C4
chr4_-_125808281 12.85 ENSRNOT00000037848
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr15_+_33600337 12.35 ENSRNOT00000075965
CKLF-like MARVEL transmembrane domain containing 5
chr18_-_64177729 12.18 ENSRNOT00000022347
melanocortin 2 receptor
chr7_-_11018160 11.98 ENSRNOT00000092061
amino-terminal enhancer of split
chr4_-_179307095 11.97 ENSRNOT00000021193
branched chain amino acid transaminase 1
chr8_+_74868681 11.72 ENSRNOT00000039376

chr14_+_12218553 11.72 ENSRNOT00000003237
protein kinase, cGMP-dependent, type II
chr20_-_4823475 11.50 ENSRNOT00000082536
ENSRNOT00000001114
ATPase H+ transporting V1 subunit G2
chrX_-_152642531 11.30 ENSRNOT00000085037
gamma-aminobutyric acid type A receptor alpha3 subunit
chr5_+_139783951 10.96 ENSRNOT00000081333
regulating synaptic membrane exocytosis 3
chr7_-_138483612 10.96 ENSRNOT00000085620
solute carrier family 38, member 4
chr8_+_53411316 10.87 ENSRNOT00000011107
ENSRNOT00000086957
transmembrane protease, serine 5
chr3_-_48535909 10.51 ENSRNOT00000008148
fibroblast activation protein, alpha
chr17_-_10766253 10.19 ENSRNOT00000000117
complexin 2
chr3_+_63379031 9.99 ENSRNOT00000068199
oxysterol binding protein-like 6
chr1_-_222246765 9.86 ENSRNOT00000087285
ENSRNOT00000028731
DnaJ heat shock protein family (Hsp40) member C4
chr2_+_121165137 9.75 ENSRNOT00000016236
SRY box 2
chr5_-_2982603 9.64 ENSRNOT00000045460
potassium voltage-gated channel subfamily B member 2
chr3_+_56056925 9.58 ENSRNOT00000088351
ENSRNOT00000010508
kelch-like family member 23
chr8_-_39460844 9.24 ENSRNOT00000048875
PBX/knotted 1 homeobox 2
chr12_-_42492328 9.12 ENSRNOT00000011552
T-box 3
chr8_-_23063041 9.09 ENSRNOT00000018416
ELAV like RNA binding protein 3
chr3_-_176459533 8.84 ENSRNOT00000079283
Sodium/potassium transporting ATPase interacting 4
chr8_-_120446455 8.80 ENSRNOT00000085161
ENSRNOT00000042854
ENSRNOT00000037199
cAMP regulated phosphoprotein 21
chr20_-_5020150 8.76 ENSRNOT00000001146
suppressor APC domain containing 1
chr7_+_78131232 8.74 ENSRNOT00000039984
regulating synaptic membrane exocytosis 2
chr2_+_144861455 8.65 ENSRNOT00000093284
ENSRNOT00000019748
ENSRNOT00000072110
doublecortin-like kinase 1
chr10_-_27366665 8.57 ENSRNOT00000004725
gamma-aminobutyric acid type A receptor alpha1 subunit
chr3_+_172385672 8.49 ENSRNOT00000090989
GNAS complex locus
chr10_-_36323055 8.30 ENSRNOT00000081026
zinc finger protein 354C
chr8_+_117836701 8.17 ENSRNOT00000043345
plexin B1
chr19_-_37427989 8.16 ENSRNOT00000022863
tubulin polymerization-promoting protein family member 3
chr10_-_36322356 8.06 ENSRNOT00000000248
zinc finger protein 354C
chr1_-_89488223 7.88 ENSRNOT00000028624
FXYD domain-containing ion transport regulator 1
chrX_-_1704033 7.73 ENSRNOT00000051956
ubiquitin specific peptidase 11
chrX_-_13279082 7.67 ENSRNOT00000051898
ENSRNOT00000060857
tetraspanin 7
chr13_+_51034256 7.45 ENSRNOT00000004528
ENSRNOT00000046854
ENSRNOT00000087320
myosin binding protein H
chr1_-_198232344 7.35 ENSRNOT00000080988
aldolase, fructose-bisphosphate A
chr12_-_42492526 7.27 ENSRNOT00000084018
T-box 3
chr10_+_69737328 7.04 ENSRNOT00000055999
ENSRNOT00000076773
transmembrane protein 132E
chr3_+_95711555 6.79 ENSRNOT00000006302
paired box 6
chr11_+_86797557 6.54 ENSRNOT00000083049
ENSRNOT00000046594
transport and golgi organization 2 homolog
chr16_-_19872774 6.50 ENSRNOT00000000060
abhydrolase domain containing 8
chr19_+_60104804 6.49 ENSRNOT00000078559
par-3 family cell polarity regulator
chr19_+_25095089 6.26 ENSRNOT00000041717
protein kinase cAMP-activated catalytic subunit alpha
chr6_+_126018841 6.11 ENSRNOT00000089840
ENSRNOT00000088089
solute carrier family 24 member 4
chr1_+_213870502 6.04 ENSRNOT00000086483
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr6_-_104409005 5.96 ENSRNOT00000040965
coiled-coil domain containing 177
chr10_+_56627411 5.88 ENSRNOT00000089108
ENSRNOT00000068493
discs large MAGUK scaffold protein 4
chr8_-_77398156 5.81 ENSRNOT00000091858
ENSRNOT00000085349
ENSRNOT00000082763
lipase C, hepatic type
chr10_-_86004096 5.74 ENSRNOT00000091978
ENSRNOT00000066855
SH3 and cysteine rich domain 2
chr1_-_72335855 5.66 ENSRNOT00000021613
coiled-coil domain containing 106
chr1_-_164307084 5.63 ENSRNOT00000086091
serpin family H member 1
chr3_-_44522930 5.60 ENSRNOT00000006963
activin A receptor type 1
chr20_+_20105047 5.34 ENSRNOT00000082181
ankyrin 3
chr1_-_101085884 5.18 ENSRNOT00000085352
reticulocalbin 3
chr11_-_87081950 5.17 ENSRNOT00000002574
DiGeorge syndrome critical region gene 6
chr19_+_387374 5.16 ENSRNOT00000075433
uncharacterized LOC102547811
chr20_-_29579578 5.13 ENSRNOT00000000700

chr3_-_111469518 5.13 ENSRNOT00000006874
NADH:ubiquinone oxidoreductase complex assembly factor 1
chr8_-_36410612 4.91 ENSRNOT00000091308
FAD-dependent oxidoreductase domain containing 1
chr1_-_80615704 4.81 ENSRNOT00000041891
apolipoprotein E
chr12_+_18531990 4.69 ENSRNOT00000036606
acetylserotonin O-methyltransferase-like
chr2_+_60180215 4.62 ENSRNOT00000084624
prolactin receptor
chr2_+_140541619 4.60 ENSRNOT00000017396
RAB33B, member RAS oncogene family
chr18_-_5314511 4.58 ENSRNOT00000022637
ENSRNOT00000079682
zinc finger protein 521
chr2_+_193275507 4.56 ENSRNOT00000091537
hypothetical protein LOC100361951
chr12_+_18516946 4.43 ENSRNOT00000029485
dehydrogenase/reductase X-linked
chr10_+_66099531 4.43 ENSRNOT00000056192
LYR motif containing 9
chr10_-_103873246 4.43 ENSRNOT00000039387
Usher syndrome 1G
chr4_+_121760773 4.38 ENSRNOT00000087069
vomeronasal 1 receptor 92
chr10_+_88914276 4.38 ENSRNOT00000087076
ENSRNOT00000055238
ATPase H+ transporting V0 subunit a1
chr2_+_85377318 4.30 ENSRNOT00000016506
ENSRNOT00000085094
semaphorin 5A
chr1_-_80615525 4.28 ENSRNOT00000091574
apolipoprotein E
chr15_+_33755478 4.23 ENSRNOT00000034073
thiamine triphosphatase
chr9_-_65916949 4.10 ENSRNOT00000077483
transmembrane protein 237
chr20_-_422464 4.09 ENSRNOT00000051646
olfactory receptor 1673
chrX_+_77065397 4.06 ENSRNOT00000090007
cytochrome c oxidase subunit 7B
chr1_-_189911571 4.04 ENSRNOT00000080996
ENSRNOT00000088536
zona pellucida glycoprotein 2
chr1_-_173393390 4.00 ENSRNOT00000050657
olfactory receptor 285
chr3_-_2719513 3.98 ENSRNOT00000020997
lipocalin 12
chr7_+_6644643 3.93 ENSRNOT00000051670
olfactory receptor 962
chr13_-_89668473 3.85 ENSRNOT00000004938
ubiquitin-fold modifier conjugating enzyme 1
chr1_+_255185629 3.85 ENSRNOT00000083002
HECT domain E3 ubiquitin protein ligase 2
chr15_+_47373120 3.82 ENSRNOT00000070815
RP1 like 1
chr9_-_65917132 3.73 ENSRNOT00000031866
transmembrane protein 237
chr11_-_62396909 3.70 ENSRNOT00000093596
ENSRNOT00000093179
zinc finger and BTB domain containing 20
chr7_-_106695570 3.66 ENSRNOT00000083517
HERV-H LTR-associating 1
chr1_+_64101018 3.64 ENSRNOT00000078640
membrane bound O-acyltransferase domain containing 7
chr20_+_25990656 3.63 ENSRNOT00000081254
leucine rich repeat transmembrane neuronal 3
chr19_-_25366806 3.61 ENSRNOT00000003762
methylthioribose-1-phosphate isomerase 1
chr8_+_129205931 3.60 ENSRNOT00000082377
ectonucleoside triphosphate diphosphohydrolase 3
chr3_-_2719135 3.59 ENSRNOT00000080257
lipocalin 12
chr20_+_5455974 3.58 ENSRNOT00000000553
ENSRNOT00000092676
prefoldin subunit 6
chr3_-_23020441 3.56 ENSRNOT00000017651
nuclear receptor subfamily 5, group A, member 1
chr13_+_48689962 3.54 ENSRNOT00000079707
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr14_-_18076907 3.50 ENSRNOT00000003472
prostate androgen-regulated mucin-like protein 1
chr18_-_63357194 3.47 ENSRNOT00000089408
ENSRNOT00000066103
spire-type actin nucleation factor 1
chr1_+_84612448 3.44 ENSRNOT00000032991

chrX_-_110230610 3.33 ENSRNOT00000093401
serpin family A member 7
chr3_-_160465143 3.33 ENSRNOT00000040156
translocase of outer mitochondrial membrane 34
chr1_+_83714347 3.30 ENSRNOT00000085245
cytochrome P450, family 2, subfamily a, polypeptide 1
chr10_-_94406949 3.28 ENSRNOT00000012533
coiled-coil domain containing 47
chr9_+_3896337 3.25 ENSRNOT00000079166
protein tyrosine phosphatase type IVA 1
chr2_-_184951950 3.24 ENSRNOT00000093486
family with sequence similarity 160, member A1
chr15_-_5894854 3.23 ENSRNOT00000024427
CD99 molecule-like 2
chr1_-_261669584 3.22 ENSRNOT00000020568
ENSRNOT00000076555
cartilage acidic protein 1
chr15_+_5265307 3.16 ENSRNOT00000031807
CD99 antigen-like protein 2
chr12_+_38375416 3.14 ENSRNOT00000078530
CAP-GLY domain containing linker protein 1
chr7_-_2623781 3.04 ENSRNOT00000004173
SPRY domain containing 4
chr16_-_20641908 3.02 ENSRNOT00000026846
elongation factor for RNA polymerase II
chr10_-_14703668 2.94 ENSRNOT00000024767
tryptase alpha/beta 1
chr3_-_107760550 2.94 ENSRNOT00000077091
ENSRNOT00000051638
Meis homeobox 2
chr10_+_90550147 2.89 ENSRNOT00000032944
frizzled class receptor 2
chr2_-_105224295 2.89 ENSRNOT00000014178
angiotensin II receptor, type 1b
chr7_-_16068823 2.87 ENSRNOT00000073630
olfactory receptor 922
chr3_+_100788806 2.82 ENSRNOT00000083289
ENSRNOT00000090445
brain-derived neurotrophic factor
chr8_+_122003916 2.78 ENSRNOT00000091980
cytoplasmic linker associated protein 2
chr4_+_85427555 2.76 ENSRNOT00000015469
family with sequence similarity 188, member B
chr1_+_276309927 2.69 ENSRNOT00000067460
ENSRNOT00000066236
vesicle transport through interaction with t-SNAREs 1A
chr7_+_121311024 2.69 ENSRNOT00000092260
ENSRNOT00000023066
ENSRNOT00000081377
synaptogyrin 1
chr1_-_88780425 2.67 ENSRNOT00000074494
succinate dehydrogenase complex assembly factor 1
chr20_+_5456235 2.65 ENSRNOT00000092555
prefoldin subunit 6
chr7_-_116063078 2.55 ENSRNOT00000076932
ENSRNOT00000035496
glycosylphosphatidylinositol anchored molecule like
chr18_-_80865584 2.52 ENSRNOT00000021750
teashirt zinc finger homeobox 1
chr12_+_2046472 2.48 ENSRNOT00000001289
zinc finger protein 358
chr19_-_36157924 2.47 ENSRNOT00000072022

chr6_+_129538982 2.44 ENSRNOT00000083626
ENSRNOT00000082522
adenylate kinase 7
chr1_+_215460226 2.43 ENSRNOT00000027270
hypothetical protein LOC685544
chr19_+_85606 2.42 ENSRNOT00000015724
carboxylesterase 2E
chr10_+_70520206 2.39 ENSRNOT00000088198
ENSRNOT00000090446
ENSRNOT00000085799
adaptor-related protein complex 2, beta 1 subunit
chr1_-_225329770 2.37 ENSRNOT00000027459
asparaginase like 1
chr10_-_87578854 2.30 ENSRNOT00000065619
similar to keratin associated protein 4-7
chr5_+_58144705 2.23 ENSRNOT00000019886
galactose-1-phosphate uridylyltransferase
chr20_-_35342 2.20 ENSRNOT00000048277
olfactory receptor 2B11-like
chr16_-_81583916 2.18 ENSRNOT00000026281
transmembrane and coiled-coil domain-containing protein 3
chr12_+_4248808 2.18 ENSRNOT00000042410

chr2_-_198719202 2.12 ENSRNOT00000028801
RNA polymerase III subunit G like
chr11_+_30363280 2.11 ENSRNOT00000002885
superoxide dismutase 1, soluble
chr3_-_77525518 2.11 ENSRNOT00000049513
olfactory receptor 663
chr12_-_39641285 2.08 ENSRNOT00000001729
anaphase promoting complex subunit 7
chr19_+_37330930 2.02 ENSRNOT00000022439
pleckstrin homology and RhoGEF domain containing G4
chr9_-_104478959 1.98 ENSRNOT00000034533

chr4_+_121899292 1.94 ENSRNOT00000077949
vomeronasal 1 receptor 97
chr4_-_55740627 1.92 ENSRNOT00000010658
paired box 4
chr12_+_22229079 1.90 ENSRNOT00000001911
G protein subunit beta 2
chr5_+_156618962 1.87 ENSRNOT00000020069
SH2 domain containing 5
chr14_-_65153013 1.85 ENSRNOT00000071542

chr3_-_6017597 1.82 ENSRNOT00000065867
bromodomain containing 3
chr8_+_19972793 1.80 ENSRNOT00000068066
olfactory receptor 1159
chr1_+_86948918 1.78 ENSRNOT00000084839
sirtuin 2
chr10_+_105235289 1.73 ENSRNOT00000075548
galanin receptor 2
chr3_+_8547349 1.68 ENSRNOT00000079108
ENSRNOT00000091697
spectrin, alpha, non-erythrocytic 1
chr2_+_186630278 1.67 ENSRNOT00000021604
similar to elongation protein 4 homolog
chr16_-_2226121 1.62 ENSRNOT00000091513
sarcolemma associated protein
chr1_-_185569190 1.62 ENSRNOT00000090773
similar to sid2057p
chr6_-_108167185 1.61 ENSRNOT00000015545
aldehyde dehydrogenase 6 family, member A1
chr1_-_72339395 1.60 ENSRNOT00000021772
zinc finger protein 580
chr4_+_157057601 1.58 ENSRNOT00000040592
Zinc finger protein 42-like
chr20_+_4823662 1.56 ENSRNOT00000090028
NFKB inhibitor like 1
chr16_-_75028977 1.55 ENSRNOT00000058071
defensin beta 13
chr1_+_84009268 1.54 ENSRNOT00000057230
ENSRNOT00000081121
similar to FLJ41131 protein
chr1_-_65659945 1.54 ENSRNOT00000058574
ring finger protein 225
chr1_-_221431713 1.53 ENSRNOT00000028485
transmembrane 7 superfamily member 2
chr1_+_79898551 1.49 ENSRNOT00000019069
Myb-related transcription factor, partner of profilin
chr17_-_32953641 1.46 ENSRNOT00000023332
Werner helicase interacting protein 1
chr8_+_64531594 1.43 ENSRNOT00000036798
GRAM domain containing 2
chr10_+_14105750 1.42 ENSRNOT00000090552
methionine sulfoxide reductase B1
chr15_-_60289763 1.32 ENSRNOT00000038579
family with sequence similarity 216, member B
chr4_+_140247313 1.31 ENSRNOT00000040255
ENSRNOT00000064025
ENSRNOT00000041130
ENSRNOT00000043646
inositol 1,4,5-trisphosphate receptor, type 1
chr1_+_100593892 1.26 ENSRNOT00000027062
potassium voltage-gated channel subfamily C member 3
chr11_-_23063414 1.26 ENSRNOT00000043396
olfactory receptor 6C6-like
chr1_+_47972399 1.19 ENSRNOT00000033408
ENSRNOT00000077707
acetyl-CoA acetyltransferase 2
chr3_+_113131327 1.16 ENSRNOT00000018460
tubulin, gamma complex associated protein 4
chr20_-_10257044 1.16 ENSRNOT00000068289
WD repeat domain 4
chr5_-_137321121 1.15 ENSRNOT00000027414
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chrX_+_21499934 1.13 ENSRNOT00000090890
ENSRNOT00000081037
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
chr10_-_14072230 1.10 ENSRNOT00000018405
transducin (beta)-like 3
chr5_-_137901590 1.10 ENSRNOT00000044946
olfactory receptor 868
chrX_-_1369384 1.09 ENSRNOT00000013745
TIMP metallopeptidase inhibitor 1
chr5_-_136762986 1.04 ENSRNOT00000026852
artemin
chr4_-_157274755 1.04 ENSRNOT00000088895
atrophin-1-like
chr14_-_79987915 0.99 ENSRNOT00000089006
actin filament associated protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb7b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.2 18.6 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
5.5 16.4 GO:0060932 sinoatrial node cell development(GO:0060931) His-Purkinje system cell differentiation(GO:0060932)
5.0 15.0 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
4.9 19.6 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
4.0 12.0 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
3.9 11.7 GO:2001226 negative regulation of chloride transport(GO:2001226)
3.5 10.5 GO:0097325 melanocyte proliferation(GO:0097325)
3.0 15.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
3.0 9.1 GO:1903000 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
2.8 8.5 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
2.8 19.6 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
2.7 8.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
2.4 9.8 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
2.4 25.9 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
2.3 6.8 GO:0021918 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
2.2 24.2 GO:0070327 thyroid hormone transport(GO:0070327)
2.2 13.1 GO:0060721 regulation of spongiotrophoblast cell proliferation(GO:0060721) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
2.1 14.6 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
2.0 7.9 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
1.9 5.8 GO:0010034 response to acetate(GO:0010034)
1.9 5.6 GO:0061443 endocardial cushion cell differentiation(GO:0061443)
1.9 13.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.6 11.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
1.5 4.6 GO:0045054 constitutive secretory pathway(GO:0045054)
1.4 4.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
1.3 5.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.3 12.0 GO:2000210 positive regulation of anoikis(GO:2000210)
1.2 5.9 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
1.2 3.5 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
1.1 6.5 GO:0003383 apical constriction(GO:0003383)
1.0 6.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
1.0 4.0 GO:0060468 prevention of polyspermy(GO:0060468)
1.0 29.5 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.0 2.9 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
1.0 2.9 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.9 3.5 GO:0019042 viral latency(GO:0019042) release from viral latency(GO:0019046)
0.8 10.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.8 2.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.8 3.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.8 3.9 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.7 7.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.7 2.1 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.7 5.6 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.7 8.7 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.7 8.6 GO:0071420 cellular response to histamine(GO:0071420)
0.6 3.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.6 7.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.6 3.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.6 1.8 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.6 14.0 GO:0060992 response to fungicide(GO:0060992)
0.6 2.2 GO:0061622 UDP-glucose metabolic process(GO:0006011) glycolytic process through glucose-1-phosphate(GO:0061622)
0.6 4.4 GO:0050957 equilibrioception(GO:0050957)
0.5 4.3 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.5 1.6 GO:0006574 valine catabolic process(GO:0006574)
0.5 2.7 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.5 4.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.5 3.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.5 2.0 GO:1902606 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.5 1.4 GO:0030091 protein repair(GO:0030091)
0.5 3.3 GO:0009804 coumarin metabolic process(GO:0009804)
0.5 17.5 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.4 2.5 GO:0060023 soft palate development(GO:0060023)
0.4 14.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.4 3.6 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.4 6.3 GO:0019236 response to pheromone(GO:0019236)
0.4 1.2 GO:0016094 polyprenol biosynthetic process(GO:0016094) ketone body catabolic process(GO:0046952)
0.4 2.4 GO:0006528 asparagine metabolic process(GO:0006528)
0.4 4.4 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.4 3.6 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.4 11.0 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.3 1.0 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.3 1.0 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.3 6.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.3 1.6 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.3 9.6 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.3 1.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.3 2.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 3.3 GO:0006983 ER overload response(GO:0006983)
0.3 1.1 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
0.3 2.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 4.9 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 2.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 1.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2 1.3 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.2 3.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.2 8.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 0.8 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.2 1.6 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 1.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 12.2 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.2 11.9 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.2 15.6 GO:0021766 hippocampus development(GO:0021766)
0.1 14.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 11.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 17.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 0.8 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.9 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 3.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 6.7 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.6 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 4.8 GO:0018149 peptide cross-linking(GO:0018149)
0.1 8.8 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 3.5 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.7 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.9 GO:0010889 regulation of sequestering of triglyceride(GO:0010889)
0.1 6.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 0.5 GO:0001842 neural fold formation(GO:0001842)
0.1 4.9 GO:0031016 pancreas development(GO:0031016)
0.1 12.3 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 4.4 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0001927 exocyst assembly(GO:0001927)
0.0 1.1 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.6 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 1.7 GO:0051693 actin filament capping(GO:0051693)
0.0 0.3 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 1.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.9 GO:0021591 ventricular system development(GO:0021591)
0.0 1.4 GO:0032720 negative regulation of tumor necrosis factor production(GO:0032720)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.4 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 3.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 4.0 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 1.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 6.9 GO:0070997 neuron death(GO:0070997)
0.0 6.0 GO:0006869 lipid transport(GO:0006869)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 21.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 3.2 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 2.2 GO:0006898 receptor-mediated endocytosis(GO:0006898)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 25.9 GO:0042587 glycogen granule(GO:0042587)
1.8 9.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.7 10.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
1.7 19.8 GO:0098839 postsynaptic density membrane(GO:0098839)
1.1 5.6 GO:0048179 activin receptor complex(GO:0048179)
1.1 6.5 GO:0033269 internode region of axon(GO:0033269)
0.9 15.9 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.9 13.0 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.9 19.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.8 6.2 GO:0016272 prefoldin complex(GO:0016272)
0.8 3.0 GO:0035363 histone locus body(GO:0035363)
0.7 6.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.6 7.4 GO:0005859 muscle myosin complex(GO:0005859)
0.5 5.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.5 16.5 GO:0030673 axolemma(GO:0030673)
0.4 7.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.4 2.8 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.4 4.6 GO:0005796 Golgi lumen(GO:0005796)
0.4 5.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 19.7 GO:0048786 presynaptic active zone(GO:0048786)
0.3 1.7 GO:0008091 spectrin(GO:0008091)
0.3 1.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.3 3.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 8.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 9.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 19.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3 1.8 GO:0043219 lateral loop(GO:0043219)
0.2 7.8 GO:0035869 ciliary transition zone(GO:0035869)
0.2 14.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 2.9 GO:0031983 vesicle lumen(GO:0031983)
0.2 4.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 1.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 7.9 GO:0034707 chloride channel complex(GO:0034707)
0.2 9.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 17.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.2 1.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.2 9.2 GO:0045171 intercellular bridge(GO:0045171)
0.2 1.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 4.6 GO:0001533 cornified envelope(GO:0001533)
0.2 2.8 GO:0030061 mitochondrial crista(GO:0030061)
0.2 1.0 GO:0044326 dendritic spine neck(GO:0044326)
0.2 2.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 9.4 GO:0045178 basal part of cell(GO:0045178)
0.1 2.1 GO:0031045 dense core granule(GO:0031045)
0.1 4.0 GO:0005771 multivesicular body(GO:0005771)
0.1 1.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.7 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.1 4.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 1.0 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 5.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 5.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 2.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 12.2 GO:0030426 growth cone(GO:0030426)
0.0 0.8 GO:0000242 pericentriolar material(GO:0000242)
0.0 3.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 7.5 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 10.5 GO:0014069 postsynaptic density(GO:0014069)
0.0 11.6 GO:0031965 nuclear membrane(GO:0031965)
0.0 2.7 GO:0043195 terminal bouton(GO:0043195)
0.0 8.2 GO:0043235 receptor complex(GO:0043235)
0.0 3.6 GO:0001650 fibrillar center(GO:0001650)
0.0 3.3 GO:0031968 mitochondrial outer membrane(GO:0005741) organelle outer membrane(GO:0031968)
0.0 3.5 GO:0005770 late endosome(GO:0005770)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923)
0.0 7.5 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 27.6 GO:0005739 mitochondrion(GO:0005739)
0.0 1.6 GO:0042383 sarcolemma(GO:0042383)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 1.0 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.0 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
3.9 15.6 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
3.6 18.0 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
3.0 15.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
3.0 9.1 GO:0046911 metal chelating activity(GO:0046911)
3.0 35.9 GO:0070324 thyroid hormone binding(GO:0070324)
2.9 8.6 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
2.8 14.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
2.4 12.2 GO:0004977 melanocortin receptor activity(GO:0004977)
1.6 18.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
1.5 4.6 GO:0004925 prolactin receptor activity(GO:0004925)
1.4 8.5 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
1.3 11.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.1 4.3 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.1 7.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.0 19.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
1.0 5.9 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
1.0 5.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.9 5.6 GO:0016361 activin receptor activity, type I(GO:0016361)
0.9 6.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.7 6.8 GO:0003680 AT DNA binding(GO:0003680)
0.7 9.8 GO:0035198 miRNA binding(GO:0035198)
0.6 2.4 GO:0004127 cytidylate kinase activity(GO:0004127)
0.6 1.8 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.6 8.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.6 2.9 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.6 7.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.5 14.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.5 7.6 GO:0001972 retinoic acid binding(GO:0001972)
0.5 4.7 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.5 22.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.5 11.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.4 2.2 GO:0005534 galactose binding(GO:0005534)
0.4 2.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.4 9.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.4 3.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.4 1.2 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.4 9.1 GO:0017091 AU-rich element binding(GO:0017091)
0.4 3.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.4 12.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.4 1.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.4 2.8 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.3 17.8 GO:0015459 potassium channel regulator activity(GO:0015459)
0.3 1.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 1.3 GO:0032190 acrosin binding(GO:0032190)
0.3 9.2 GO:0003785 actin monomer binding(GO:0003785)
0.3 10.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.3 4.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.3 11.4 GO:0030507 spectrin binding(GO:0030507)
0.3 3.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.2 18.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.2 2.0 GO:0004966 galanin receptor activity(GO:0004966)
0.2 10.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 10.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 6.0 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 2.4 GO:0008242 omega peptidase activity(GO:0008242)
0.2 3.6 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.2 19.7 GO:0044325 ion channel binding(GO:0044325)
0.2 2.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 6.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 1.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 4.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.8 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 3.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 14.0 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.1 2.2 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.1 11.0 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.1 1.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 8.9 GO:0051082 unfolded protein binding(GO:0051082)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 8.9 GO:0005319 lipid transporter activity(GO:0005319)
0.1 1.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 6.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 3.6 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.1 3.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.6 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.9 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 4.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 14.0 GO:0003924 GTPase activity(GO:0003924)
0.0 3.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 2.4 GO:0030276 clathrin binding(GO:0030276)
0.0 1.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.9 GO:0017022 myosin binding(GO:0017022)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 3.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 1.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 2.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.4 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 21.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 2.1 GO:0019903 protein phosphatase binding(GO:0019903)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 22.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.4 20.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.4 20.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 5.2 PID ALK2 PATHWAY ALK2 signaling events
0.4 14.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.3 15.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 12.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.3 10.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 13.1 PID TNF PATHWAY TNF receptor signaling pathway
0.2 10.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 8.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 3.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 8.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 6.8 PID CDC42 PATHWAY CDC42 signaling events
0.1 15.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 6.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 5.7 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 2.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 19.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
1.0 18.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.0 11.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.9 14.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.9 19.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.9 16.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.8 13.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.8 13.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.5 20.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.5 11.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.5 26.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.4 10.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.4 6.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.3 6.2 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.3 6.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 18.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 7.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.2 4.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 4.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 7.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 8.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 3.6 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.2 10.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 4.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 4.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 2.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 3.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.0 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 6.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 5.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 13.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 4.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 4.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis